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CL:0000501

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Name:granulosa cell
Namespace:FANTOM
Definition:"A supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge. Granulosa cells form a single layer around the mammalian oocyte in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the ovum in the Graafian follicle. The major functions of granulosa cells include the production of steroids and LH receptors." [MESH:A.05.360.319.114.630.535.200]
Xrefs:
links:

BTO:0000542

FMA:18718
Synonyms: "granulosa cell of ovary" EXACT []


Ontology association
Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.

link to ontology dataset
data


Parents

is_a:CL:0000174(steroid hormone secreting cell),CL:0002174(follicular cell of ovary)



Children


derives from:FF:0102285 (granulosa cell line sample)

Ontology Tree: Loaded from BioPortal


FF samples
It includes FANTOM5 samples that overlay the Cell ontology.


Human (Homo sapiens)

Mouse (Mus musculus)


Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000501 (granulosa cell), sorted by p-values
Analyst: Hideya Kawaji

link to source dataset
human : data
mouse : data


P-valueFFCPShort description
4.66e-66FFCP PHASE2:Hg19::chr1:248067410..248067413,+#_47cd29ac5e38496c48e2f5fd7085a77ep@chr1:248067410..248067413, +
4.66e-66FFCP PHASE1:Hg19::chr1:248067410..248067413,+#_47cd29ac5e38496c48e2f5fd7085a77ep@chr1:248067410..248067413, +
1.46e-50FFCP PHASE2:Hg19::chr2:227587084..227587105,+#_84877510a455ccbedaa5b4d6566d8c4cp@chr2:227587084..227587105, +
1.46e-50FFCP PHASE1:Hg19::chr2:227587084..227587105,+#_84877510a455ccbedaa5b4d6566d8c4cp@chr2:227587084..227587105, +
2.42e-50FFCP PHASE2:Hg19::chr12:78359973..78359982,+#_9ad56f36d3143c94eca9625171e36178p34@NAV3
2.42e-50FFCP PHASE1:Hg19::chr12:78359973..78359982,+#_9ad56f36d3143c94eca9625171e36178p34@NAV3
1.48e-40FFCP PHASE1:Hg19::chr11:77282391..77282402,+#_9dafebf019e9e524d78c8f6ec25e517bp@chr11:77282391..77282402, +
1.48e-40FFCP PHASE2:Hg19::chr11:77282391..77282402,+#_9dafebf019e9e524d78c8f6ec25e517bp@chr11:77282391..77282402, +
2.21e-40FFCP PHASE2:Hg19::chr9:124044161..124044173,+#_d84423f5303d23c62b85aeb799a53297p@chr9:124044161..124044173, +
2.21e-40FFCP PHASE1:Hg19::chr9:124044161..124044173,+#_d84423f5303d23c62b85aeb799a53297p@chr9:124044161..124044173, +
3.61e-34FFCP PHASE2:Hg19::chr1:185853036..185853046,+#_1d3636ae16fc0e8273fe7068bd3f5b5cp@chr1:185853036..185853046, +
3.61e-34FFCP PHASE1:Hg19::chr1:185853036..185853046,+#_1d3636ae16fc0e8273fe7068bd3f5b5cp@chr1:185853036..185853046, +
5.05e-34FFCP PHASE2:Hg19::chr1:186116540..186116557,+#_23a499ee374415b78289ce75fe426532p@chr1:186116540..186116557, +
5.05e-34FFCP PHASE1:Hg19::chr1:186116540..186116557,+#_23a499ee374415b78289ce75fe426532p@chr1:186116540..186116557, +
5.05e-34FFCP PHASE2:Hg19::chr1:248080895..248080906,+#_23a499ee374415b78289ce75fe426532+, p@chr1:248080895..248080906
5.05e-34FFCP PHASE1:Hg19::chr4:138999555..138999575,-#_23a499ee374415b78289ce75fe426532p@chr4:138999555..138999575, -
5.05e-34FFCP PHASE2:Hg19::chr4:138999555..138999575,-#_23a499ee374415b78289ce75fe426532p@chr4:138999555..138999575, -
5.05e-34FFCP PHASE1:Hg19::chr1:248080895..248080906,+#_23a499ee374415b78289ce75fe426532p@chr1:248080895..248080906, +
7.06e-34FFCP PHASE1:Hg19::chr1:185720104..185720113,+#_022b59984677a7b0de98938e754e26cfp@chr1:185720104..185720113, +
7.06e-34FFCP PHASE2:Hg19::chr1:185720104..185720113,+#_022b59984677a7b0de98938e754e26cfp@chr1:185720104..185720113, +
9.99e-30FFCP PHASE1:Hg19::chr5:145427166..145427178,+#_924d0aa15b99ddbe47b99e62b4f14df5p@chr5:145427166..145427178, +
9.99e-30FFCP PHASE2:Hg19::chr5:145427166..145427178,+#_924d0aa15b99ddbe47b99e62b4f14df5+, p@chr5:145427166..145427178
1.33e-29FFCP PHASE1:Hg19::chr9:32783532..32783551,+#_ab9c120c26256af1688ebdddcd0ecc89p2@TMEM215
1.33e-29FFCP PHASE2:Hg19::chr9:32783532..32783551,+#_ab9c120c26256af1688ebdddcd0ecc89p2@TMEM215
1.33e-29FFCP PHASE1:Hg19::chr18:19748482..19748490,-#_ab9c120c26256af1688ebdddcd0ecc89p@chr18:19748482..19748490, -
1.33e-29FFCP PHASE2:Hg19::chr18:19748482..19748490,-#_ab9c120c26256af1688ebdddcd0ecc89p@chr18:19748482..19748490, -
1.33e-29FFCP PHASE2:Hg19::chr3:111633072..111633073,+#_ab9c120c26256af1688ebdddcd0ecc89p@chr3:111633072..111633073, +
1.33e-29FFCP PHASE1:Hg19::chr3:111633072..111633073,+#_ab9c120c26256af1688ebdddcd0ecc89p@chr3:111633072..111633073, +
2.37e-29FFCP PHASE2:Hg19::chr11:46848363..46848374,-#_678d8bfcbc7593eb013058ec0ce2694ap6@CKAP5
2.37e-29FFCP PHASE1:Hg19::chr8:11534512..11534519,+#_678d8bfcbc7593eb013058ec0ce2694ap7@GATA4
2.37e-29FFCP PHASE2:Hg19::chr6:5261661..5261664,-#_678d8bfcbc7593eb013058ec0ce2694ap7@LYRM4
2.37e-29FFCP PHASE1:Hg19::chr11:120110546..120110551,-#_678d8bfcbc7593eb013058ec0ce2694ap@chr11:120110546..120110551, -
2.37e-29FFCP PHASE1:Hg19::chr6:5261661..5261664,-#_678d8bfcbc7593eb013058ec0ce2694ap7@LYRM4
2.37e-29FFCP PHASE1:Hg19::chr11:46848363..46848374,-#_678d8bfcbc7593eb013058ec0ce2694ap6@CKAP5
2.37e-29FFCP PHASE2:Hg19::chr11:120110546..120110551,-#_678d8bfcbc7593eb013058ec0ce2694ap@chr11:120110546..120110551, -
2.37e-29FFCP PHASE2:Hg19::chr8:11534512..11534519,+#_678d8bfcbc7593eb013058ec0ce2694ap7@GATA4
3.16e-29FFCP PHASE1:Hg19::chr2:49381628..49381639,-#_d94d256d0375fe080a5047bd1052fc4bp2@FSHR
3.16e-29FFCP PHASE2:Hg19::chr2:49381628..49381639,-#_d94d256d0375fe080a5047bd1052fc4bp2@FSHR
2.16e-26FFCP PHASE2:Hg19::chr11:46887017..46887024,-#_0116f02832e4ffc2c896ccb5f44dac65p@chr11:46887017..46887024, -
2.16e-26FFCP PHASE1:Hg19::chr11:46887017..46887024,-#_0116f02832e4ffc2c896ccb5f44dac65p@chr11:46887017..46887024, -
3.58e-26FFCP PHASE2:Hg19::chr17:6374648..6374688,-#_f41141538d902162c73a5d5fd366f78ep@chr17:6374648..6374688, -
3.58e-26FFCP PHASE1:Hg19::chr17:6374648..6374688,-#_f41141538d902162c73a5d5fd366f78ep@chr17:6374648..6374688, -
1.26e-25FFCP PHASE1:Hg19::chr5:145340760..145340764,+#_8ec7c705ed225b85f3c73cc6cf649bb6p@chr5:145340760..145340764, +
1.26e-25FFCP PHASE2:Hg19::chr5:145340760..145340764,+#_8ec7c705ed225b85f3c73cc6cf649bb6p@chr5:145340760..145340764, +
1.34e-23FFCP PHASE2:Hg19::chr5:83644408..83644410,-#_e0f663952b062f22595e9edfe5813b94p@chr5:83644408..83644410, -
1.34e-23FFCP PHASE1:Hg19::chr5:83644408..83644410,-#_e0f663952b062f22595e9edfe5813b94p@chr5:83644408..83644410, -
1.67e-23FFCP PHASE1:Hg19::chr3:197026018..197026029,-#_cab4a601933c7360740597d1608b361bp34@DLG1
1.67e-23FFCP PHASE2:Hg19::chr3:197026018..197026029,-#_cab4a601933c7360740597d1608b361bp34@DLG1
3.28e-23FFCP PHASE2:Hg19::chr11:1580303..1580327,-#_0c01279392cc78ab23eaa943a1457a9dp@chr11:1580303..1580327, -
3.28e-23FFCP PHASE1:Hg19::chr11:1580303..1580327,-#_0c01279392cc78ab23eaa943a1457a9dp@chr11:1580303..1580327, -
4.1e-23FFCP PHASE2:Hg19::chr2:204534759..204534765,+#_1d703ff6f195dc4fc90d6978853daf3a+, p@chr2:204534759..204534765
4.1e-23FFCP PHASE1:Hg19::chr2:204534759..204534765,+#_1d703ff6f195dc4fc90d6978853daf3ap@chr2:204534759..204534765, +
5.13e-23FFCP PHASE1:Hg19::chr10:45496353..45496379,-#_8e3709ab2117b46ea636dbf54153784bp6@C10orf25
5.13e-23FFCP PHASE2:Hg19::chr10:45496353..45496379,-#_8e3709ab2117b46ea636dbf54153784bp6@C10orf25
1.88e-21FFCP PHASE2:Hg19::chr3:96336938..96336956,-#_61322040c8f1f0afe737743260dafa15p@chr3:96336938..96336956, -
1.88e-21FFCP PHASE1:Hg19::chr3:96336938..96336956,-#_61322040c8f1f0afe737743260dafa15p@chr3:96336938..96336956, -
2.3e-21FFCP PHASE1:Hg19::chr3:87004049..87004053,-#_8964e1f6be7e7451b3fafb642cfa2179p@chr3:87004049..87004053, -
2.3e-21FFCP PHASE2:Hg19::chr3:87004049..87004053,-#_8964e1f6be7e7451b3fafb642cfa2179p@chr3:87004049..87004053, -
2.82e-21FFCP PHASE1:Hg19::chr12:78359984..78359998,+#_a254cafe5dfbebe839eee5a8cfca6254p19@NAV3
2.82e-21FFCP PHASE2:Hg19::chr1:225962665..225962674,+#_a254cafe5dfbebe839eee5a8cfca6254p@chr1:225962665..225962674, +
2.82e-21FFCP PHASE1:Hg19::chr1:225962665..225962674,+#_a254cafe5dfbebe839eee5a8cfca6254p@chr1:225962665..225962674, +
2.82e-21FFCP PHASE2:Hg19::chr12:78359984..78359998,+#_a254cafe5dfbebe839eee5a8cfca6254p19@NAV3
5.16e-21FFCP PHASE1:Hg19::chr11:503354..503369,+#_22f7a49134497c72c8da35d51326160fp@chr11:503354..503369, +
5.16e-21FFCP PHASE2:Hg19::chr11:503354..503369,+#_22f7a49134497c72c8da35d51326160fp@chr11:503354..503369, +
1.08e-19FFCP PHASE1:Hg19::chr12:78359999..78360035,+#_9536e148840e35d4ec3dec1c66aba727p13@NAV3
1.08e-19FFCP PHASE2:Hg19::chr12:78359999..78360035,+#_9536e148840e35d4ec3dec1c66aba727p13@NAV3
1.3e-19FFCP PHASE2:Hg19::chr3:138666029..138666038,-#_59d1c68e3a0bc5bac8a320a230e85943p8@FOXL2
1.3e-19FFCP PHASE1:Hg19::chr3:138666029..138666038,-#_59d1c68e3a0bc5bac8a320a230e85943p8@FOXL2
2.25e-19FFCP PHASE2:Hg19::chr1:185880819..185880830,+#_1f53ff1f7955573a4340fdabac3810ddp@chr1:185880819..185880830, +
2.25e-19FFCP PHASE1:Hg19::chr1:185880819..185880830,+#_1f53ff1f7955573a4340fdabac3810ddp@chr1:185880819..185880830, +
2.71e-19FFCP PHASE2:Hg19::chr15:80843472..80843480,+#_94b91dad1e21c6d82ef6b3a76b09452cp22@ARNT2
2.71e-19FFCP PHASE2:Hg19::chr4:40848340..40848344,-#_94b91dad1e21c6d82ef6b3a76b09452cp@chr4:40848340..40848344, -
2.71e-19FFCP PHASE2:Hg19::chr13:45694574..45694578,+#_94b91dad1e21c6d82ef6b3a76b09452cp6@GTF2F2
2.71e-19FFCP PHASE1:Hg19::chr15:80843472..80843480,+#_94b91dad1e21c6d82ef6b3a76b09452cp22@ARNT2
2.71e-19FFCP PHASE1:Hg19::chr4:40848340..40848344,-#_94b91dad1e21c6d82ef6b3a76b09452cp@chr4:40848340..40848344, -
2.71e-19FFCP PHASE1:Hg19::chr10:47081891..47081936,+#_94b91dad1e21c6d82ef6b3a76b09452cp@chr10:47081891..47081936, +
2.71e-19FFCP PHASE2:Hg19::chr3:69442476..69442481,-#_94b91dad1e21c6d82ef6b3a76b09452cp@chr3:69442476..69442481, -
2.71e-19FFCP PHASE1:Hg19::chr13:45694574..45694578,+#_94b91dad1e21c6d82ef6b3a76b09452cp6@GTF2F2
2.71e-19FFCP PHASE1:Hg19::chr3:69442476..69442481,-#_94b91dad1e21c6d82ef6b3a76b09452cp@chr3:69442476..69442481, -
2.71e-19FFCP PHASE2:Hg19::chr10:47081891..47081936,+#_94b91dad1e21c6d82ef6b3a76b09452cp@chr10:47081891..47081936, +
3.25e-19FFCP PHASE2:Hg19::chr18:10979606..10979617,-#_5293471b760ade75302e04a22243af10p@chr18:10979606..10979617, -
3.25e-19FFCP PHASE1:Hg19::chr18:10979606..10979617,-#_5293471b760ade75302e04a22243af10p@chr18:10979606..10979617, -
4.69e-19FFCP PHASE1:Hg19::chr11:29450724..29450728,+#_fee80a739370e28a61a74ef03424c40dp@chr11:29450724..29450728, +
4.69e-19FFCP PHASE2:Hg19::chr11:29450724..29450728,+#_fee80a739370e28a61a74ef03424c40dp@chr11:29450724..29450728, +
5.26e-18FFCP PHASE2:Hg19::chr1:186159161..186159177,+#_a19d685480a2a73291e40c0bb9202a58p@chr1:186159161..186159177, +
5.26e-18FFCP PHASE1:Hg19::chr1:186159161..186159177,+#_a19d685480a2a73291e40c0bb9202a58p@chr1:186159161..186159177, +
6.23e-18FFCP PHASE1:Hg19::chr15:74220226..74220237,-#_2ec75ad8bc706e09da056a73346f9f21p6@LOC100287616
6.23e-18FFCP PHASE1:Hg19::chr3:197640146..197640157,-#_2ec75ad8bc706e09da056a73346f9f21p7@IQCG
6.23e-18FFCP PHASE2:Hg19::chr15:74220226..74220237,-#_2ec75ad8bc706e09da056a73346f9f21p6@LOC100287616
6.23e-18FFCP PHASE2:Hg19::chr3:197640146..197640157,-#_2ec75ad8bc706e09da056a73346f9f21p7@IQCG
7.37e-18FFCP PHASE1:Hg19::chr5:14231969..14231971,+#_8d371027c5c301237df502775656f309p@chr5:14231969..14231971, +
7.37e-18FFCP PHASE2:Hg19::chr5:14231969..14231971,+#_8d371027c5c301237df502775656f309p@chr5:14231969..14231971, +
7.37e-18FFCP PHASE2:Hg19::chr20:2795626..2795639,+#_8d371027c5c301237df502775656f309p1@C20orf141, p1@TMEM239
7.37e-18FFCP PHASE1:Hg19::chr20:2795626..2795639,+#_8d371027c5c301237df502775656f309p1@C20orf141, p1@TMEM239
1.03e-17FFCP PHASE1:Hg19::chr7:45928011..45928026,+#_a9560aa145c3a1dd05bf9f1f01a38f82p4@IGFBP1
1.03e-17FFCP PHASE2:Hg19::chr7:45928011..45928026,+#_a9560aa145c3a1dd05bf9f1f01a38f82p4@IGFBP1
1.22e-17FFCP PHASE2:Hg19::chr3:138666453..138666470,+#_143e3b8de90c9e28ab99e4b6664718eap4@C3orf72
1.22e-17FFCP PHASE1:Hg19::chr3:138666453..138666470,+#_143e3b8de90c9e28ab99e4b6664718eap4@C3orf72
1.04e-16FFCP PHASE1:Hg19::chr8:103367355..103367356,-#_10f6f5068c3ce0361bb3c8a5a46dca0ep@chr8:103367355..103367356, -
1.04e-16FFCP PHASE1:Hg19::chr2:49381646..49381667,-#_10f6f5068c3ce0361bb3c8a5a46dca0ep1@FSHR