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CL:0000767

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Name:basophil
Namespace:FANTOM
Definition:"Any of the immature or mature forms of a granular leukocyte that in its mature form has an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse, bluish-black granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. A basophil is CD123-positive, CD193-positive, CD203c-positive, and FceRIa-positive." [GOC:add, GOC:amm, GOC:dsd, GOC:tfm, ISBN:0721601464, MESH:D001491, PMCID:PMC2626675, PMID:11927641, PMID:19741522, PMID:21236338, PMID:9933081]
Xrefs:
links:

BTO:0000129

FMA:62862
Synonyms: "basophilic leucocyte" EXACT []
"basophilic leukocyte" EXACT []
"polymorphonuclear leucocyte" BROAD []
"polymorphonuclear leukocyte" BROAD []
Comments:Matures in the bone marrow and account for <1% of leukocytes in the peripheral blood, spleen, and bone marrow. Basophils are described as being CD11a-positive, CD11b-positive, CD13-positive, CD15-positive, CD18-positive, CD21-positive, CD25-positive, CD29-positive, CD35-positive, CD40-positive, CD40L-positive, CD44-positive, CD45R-negative, CD46-positive, CD49a-positive, CD49b-positive, CD49d-positive, CD55-positive, CD59-positive, CD62L-positive, CD63-positive, CD69-positive, CD90-negative, CD116-positive, CD117-negative, CD124-positive, CD125-positive, CD131-positive, CD161-positive, CD184-positive, CD191-positive, CD192-positive, CD197-positive, CD200R3-positive, CD218-positive, CD282-positive, CD284-positive, CD289-positive, CD290-positive, CD294-positive, natural killer cell receptor 2B4-positive, smad1-positive, CD3-negative, CD4-negative, CD7-negative, CD8-negative, CD14-negative, CD15-negative, CD16-negative, CD19-negative, CD20-negative, CD34-negative, CD36-negative, CD45R-negative, CD56-negative, CD57-negative, CD235a-negative, and GR1-negative. Transcription factors- GATA1-positive, PU.1-positive.


Ontology association
Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.

link to ontology dataset
data


Parents

is_a:CL:0000094(granulocyte)



Children


derives from:FF:0000013 (human basophil sample)

Ontology Tree: Loaded from BioPortal


FF samples
It includes FANTOM5 samples that overlay the Cell ontology.


Human (Homo sapiens)

Mouse (Mus musculus)


Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000767 (basophil), sorted by p-values
Analyst: Hideya Kawaji

link to source dataset
human : data
mouse : data


P-valueFFCPShort description
2.79e-195FFCP PHASE1:Hg19::chr11:2961841..2961848,-#_ca011a2e46da3e58070599a017fbf2eep@chr11:2961841..2961848, -
2.79e-195FFCP PHASE2:Hg19::chr11:2961841..2961848,-#_ca011a2e46da3e58070599a017fbf2eep@chr11:2961841..2961848, -
3.27e-147FFCP PHASE1:Hg19::chr13:47538203..47538205,-#_aa8e2d694081f7706e2d1e6d4087296bp@chr13:47538203..47538205, -
3.27e-147FFCP PHASE1:Hg19::chr6:159271714..159271721,+#_aa8e2d694081f7706e2d1e6d4087296bp@chr6:159271714..159271721, +
3.27e-147FFCP PHASE2:Hg19::chr13:47538203..47538205,-#_aa8e2d694081f7706e2d1e6d4087296bp@chr13:47538203..47538205, -
3.27e-147FFCP PHASE2:Hg19::chr6:159271714..159271721,+#_aa8e2d694081f7706e2d1e6d4087296bp@chr6:159271714..159271721, +
1.47e-146FFCP PHASE2:Hg19::chr8:102167891..102167895,+#_178752d67250761a871fb8730f4bbef8p@chr8:102167891..102167895, +
1.47e-146FFCP PHASE1:Hg19::chr8:102167891..102167895,+#_178752d67250761a871fb8730f4bbef8p@chr8:102167891..102167895, +
8.98e-131FFCP PHASE2:Hg19::chr13:74039989..74040003,+#_0acd15b2b5a9114e39bbb12895c0347fp@chr13:74039989..74040003, +
8.98e-131FFCP PHASE1:Hg19::chr4:47475231..47475236,-#_0acd15b2b5a9114e39bbb12895c0347fp@chr4:47475231..47475236, -
8.98e-131FFCP PHASE2:Hg19::chr11:128186999..128187003,+#_0acd15b2b5a9114e39bbb12895c0347fp@chr11:128186999..128187003, +
8.98e-131FFCP PHASE1:Hg19::chr11:128186999..128187003,+#_0acd15b2b5a9114e39bbb12895c0347fp@chr11:128186999..128187003, +
8.98e-131FFCP PHASE1:Hg19::chr13:74039989..74040003,+#_0acd15b2b5a9114e39bbb12895c0347fp@chr13:74039989..74040003, +
8.98e-131FFCP PHASE2:Hg19::chr4:47475231..47475236,-#_0acd15b2b5a9114e39bbb12895c0347fp@chr4:47475231..47475236, -
5.2e-118FFCP PHASE2:Hg19::chr4:47487155..47487166,-#_d18f6c25745917aac6c10c4fe2aceb74p@chr4:47487155..47487166, -
5.2e-118FFCP PHASE2:Hg19::chr10:17242471..17242477,-#_d18f6c25745917aac6c10c4fe2aceb74p@chr10:17242471..17242477, -
5.2e-118FFCP PHASE1:Hg19::chr4:47487155..47487166,-#_d18f6c25745917aac6c10c4fe2aceb74p@chr4:47487155..47487166, -
5.2e-118FFCP PHASE1:Hg19::chr10:17242471..17242477,-#_d18f6c25745917aac6c10c4fe2aceb74p@chr10:17242471..17242477, -
7.78e-118FFCP PHASE2:Hg19::chr2:85932253..85932262,+#_7ea746e9b3eb3a3080a5ae88e482cec4p@chr2:85932253..85932262, +
7.78e-118FFCP PHASE1:Hg19::chr2:85932253..85932262,+#_7ea746e9b3eb3a3080a5ae88e482cec4p@chr2:85932253..85932262, +
7.95e-99FFCP PHASE2:Hg19::chr4:47465894..47465904,+#_5014819755f7a49d61cd0bd4d2984fccp@chr4:47465894..47465904, +
7.95e-99FFCP PHASE1:Hg19::chr4:47465894..47465904,+#_5014819755f7a49d61cd0bd4d2984fccp@chr4:47465894..47465904, +
2.17e-98FFCP PHASE1:Hg19::chr4:130015616..130015630,-#_47bde682c0890f4b865563e50eec285cp@chr4:130015616..130015630, -
2.17e-98FFCP PHASE2:Hg19::chr4:130015616..130015630,-#_47bde682c0890f4b865563e50eec285cp@chr4:130015616..130015630, -
6.24e-88FFCP PHASE1:Hg19::chr2:98547746..98547784,-#_f12d6bd0ec067d97a62ebe75a6b09e1ap@chr2:98547746..98547784, -
6.24e-88FFCP PHASE2:Hg19::chr10:124304122..124304160,-#_f12d6bd0ec067d97a62ebe75a6b09e1ap@chr10:124304122..124304160, -
6.24e-88FFCP PHASE1:Hg19::chr10:124304122..124304160,-#_f12d6bd0ec067d97a62ebe75a6b09e1ap@chr10:124304122..124304160, -
6.24e-88FFCP PHASE2:Hg19::chr2:98547746..98547784,-#_f12d6bd0ec067d97a62ebe75a6b09e1ap@chr2:98547746..98547784, -
9.74e-88FFCP PHASE2:Hg19::chr21:15957203..15957206,-#_86fd1504dc16eb0fddd03a5f474fde6fp@chr21:15957203..15957206, -
9.74e-88FFCP PHASE1:Hg19::chr21:15957203..15957206,-#_86fd1504dc16eb0fddd03a5f474fde6fp@chr21:15957203..15957206, -
1.52e-87FFCP PHASE2:Hg19::chr4:175579439..175579451,-#_b9b7cb0fb1b864f3eccf3de75b1b1667p@chr4:175579439..175579451, -
1.52e-87FFCP PHASE1:Hg19::chr4:175579439..175579451,-#_b9b7cb0fb1b864f3eccf3de75b1b1667p@chr4:175579439..175579451, -
1.28e-84FFCP PHASE2:Hg19::chr10:129681159..129681175,-#_c32dd0332a2fdb7fee0bf874c0d396e9p@chr10:129681159..129681175, -
1.28e-84FFCP PHASE1:Hg19::chr10:129681159..129681175,-#_c32dd0332a2fdb7fee0bf874c0d396e9p@chr10:129681159..129681175, -
2.27e-84FFCP PHASE1:Hg19::chr13:73908778..73908786,+#_3a8d1dcbc71ba6f709ebcd1bcf480b2cp@chr13:73908778..73908786, +
2.27e-84FFCP PHASE2:Hg19::chr13:73908778..73908786,+#_3a8d1dcbc71ba6f709ebcd1bcf480b2cp@chr13:73908778..73908786, +
3.03e-84FFCP PHASE2:Hg19::chr5:131758672..131758682,+#_932aec986c7b39034be0474cfb0dac5ep@chr5:131758672..131758682, +
3.03e-84FFCP PHASE1:Hg19::chr5:131758672..131758682,+#_932aec986c7b39034be0474cfb0dac5ep@chr5:131758672..131758682, +
5.37e-84FFCP PHASE1:Hg19::chr11:121356186..121356201,+#_e979d630beb313284a76032cdf5061f9p@chr11:121356186..121356201, +
5.37e-84FFCP PHASE2:Hg19::chr11:121356186..121356201,+#_e979d630beb313284a76032cdf5061f9p@chr11:121356186..121356201, +
4.72e-75FFCP PHASE1:Hg19::chr1:15545407..15545411,+#_83dd435f81eebd61bea447bbc4edec82p@chr1:15545407..15545411, +
4.72e-75FFCP PHASE2:Hg19::chr1:15545407..15545411,+#_83dd435f81eebd61bea447bbc4edec82p@chr1:15545407..15545411, +
6.07e-75FFCP PHASE1:Hg19::chr4:124538142..124538152,-#_f80dcc094df6e4009c2b200851c2d18fp@chr4:124538142..124538152, -
6.07e-75FFCP PHASE1:Hg19::chr5:169831446..169831478,-#_f80dcc094df6e4009c2b200851c2d18fp@chr5:169831446..169831478, -
6.07e-75FFCP PHASE2:Hg19::chr5:169831446..169831478,-#_f80dcc094df6e4009c2b200851c2d18fp@chr5:169831446..169831478, -
6.07e-75FFCP PHASE2:Hg19::chr4:124538142..124538152,-#_f80dcc094df6e4009c2b200851c2d18fp@chr4:124538142..124538152, -
1.01e-74FFCP PHASE2:Hg19::chr1:247712219..247712230,+#_4727ec1003c3b089eafccf347e88aaeep5@C1orf150
1.01e-74FFCP PHASE1:Hg19::chr1:247712219..247712230,+#_4727ec1003c3b089eafccf347e88aaeep5@C1orf150
1.29e-74FFCP PHASE2:Hg19::chr5:106725747..106725757,+#_7944c49e6867a790ee9b33552736d7a3+, p@chr5:106725747..106725757
1.29e-74FFCP PHASE1:Hg19::chr5:106725747..106725757,+#_7944c49e6867a790ee9b33552736d7a3p@chr5:106725747..106725757, +
2.14e-74FFCP PHASE1:Hg19::chr6:167504549..167504554,-#_4525e05b6fdf1bf3bdc0c4f5527e011bp@chr6:167504549..167504554, -
2.14e-74FFCP PHASE2:Hg19::chr6:167504549..167504554,-#_4525e05b6fdf1bf3bdc0c4f5527e011bp@chr6:167504549..167504554, -
2.75e-74FFCP PHASE2:Hg19::chr6:170773733..170773744,+#_82065180a87e81f779429a6a908dcc4b+, p@chr6:170773733..170773744
2.75e-74FFCP PHASE2:Hg19::chr6:25006945..25006954,-#_82065180a87e81f779429a6a908dcc4bp@chr6:25006945..25006954, -
2.75e-74FFCP PHASE1:Hg19::chr6:170773733..170773744,+#_82065180a87e81f779429a6a908dcc4bp@chr6:170773733..170773744, +
2.75e-74FFCP PHASE1:Hg19::chr6:25006945..25006954,-#_82065180a87e81f779429a6a908dcc4bp@chr6:25006945..25006954, -
4.55e-74FFCP PHASE2:Hg19::chr12:92271427..92271444,+#_d69986aefda76491f695c6722541550ep@chr12:92271427..92271444, +
4.55e-74FFCP PHASE1:Hg19::chr12:92271427..92271444,+#_d69986aefda76491f695c6722541550e+, p@chr12:92271427..92271444
9.64e-74FFCP PHASE1:Hg19::chr3:4790645..4790663,+#_4f899352159ca0dad5b6a7d7e8e187d8p@chr3:4790645..4790663, +
9.64e-74FFCP PHASE2:Hg19::chr3:4790645..4790663,+#_4f899352159ca0dad5b6a7d7e8e187d8p@chr3:4790645..4790663, +
1.24e-73FFCP PHASE2:Hg19::chr8:125860500..125860504,+#_6b252e1c28511177712c9bdbc9b2f7f9p6@ENST00000525292
1.24e-73FFCP PHASE1:Hg19::chr12:129296519..129296565,+#_6b252e1c28511177712c9bdbc9b2f7f9p@chr12:129296519..129296565, +
1.24e-73FFCP PHASE2:Hg19::chr12:129296519..129296565,+#_6b252e1c28511177712c9bdbc9b2f7f9p@chr12:129296519..129296565, +
1.24e-73FFCP PHASE1:Hg19::chr8:125860500..125860504,+#_6b252e1c28511177712c9bdbc9b2f7f9p6@ENST00000525292
6.27e-67FFCP PHASE1:Hg19::chr6:20326681..20326699,+#_ca0c5f02c44e8b9876c227fffade1587p@chr6:20326681..20326699, +
6.27e-67FFCP PHASE2:Hg19::chr6:20326681..20326699,+#_ca0c5f02c44e8b9876c227fffade1587+, p@chr6:20326681..20326699
7.85e-67FFCP PHASE2:Hg19::chr10:48482432..48482435,+#_48d59d999164efd970ed9fe2656357b0p@chr10:48482432..48482435, +
7.85e-67FFCP PHASE1:Hg19::chr10:48482432..48482435,+#_48d59d999164efd970ed9fe2656357b0p@chr10:48482432..48482435, +
9.82e-67FFCP PHASE2:Hg19::chr2:216614478..216614489,-#_3c47dbf75163c789fc9c1d7214492b99p@chr2:216614478..216614489, -
9.82e-67FFCP PHASE1:Hg19::chr2:216614478..216614489,-#_3c47dbf75163c789fc9c1d7214492b99p@chr2:216614478..216614489, -
2.39e-66FFCP PHASE1:Hg19::chr1:212101868..212101870,+#_0ad0d3a1cbd7bc754b377b35eae4192bp@chr1:212101868..212101870, +
2.39e-66FFCP PHASE1:Hg19::chr1:30128875..30128876,+#_0ad0d3a1cbd7bc754b377b35eae4192bp@chr1:30128875..30128876, +
2.39e-66FFCP PHASE1:Hg19::chr1:33608559..33608582,+#_0ad0d3a1cbd7bc754b377b35eae4192bp@chr1:33608559..33608582, +
2.39e-66FFCP PHASE1:Hg19::chr20:809889..809897,+#_0ad0d3a1cbd7bc754b377b35eae4192bp@chr20:809889..809897, +
2.39e-66FFCP PHASE1:Hg19::chr22:25463318..25463319,-#_0ad0d3a1cbd7bc754b377b35eae4192bp@chr22:25463318..25463319, -
2.39e-66FFCP PHASE1:Hg19::chr2:28148771..28148776,-#_0ad0d3a1cbd7bc754b377b35eae4192bp@chr2:28148771..28148776, -
2.39e-66FFCP PHASE1:Hg19::chr7:128630152..128630186,-#_0ad0d3a1cbd7bc754b377b35eae4192bp@chr7:128630152..128630186, -
2.39e-66FFCP PHASE2:Hg19::chr12:12537737..12537747,+#_0ad0d3a1cbd7bc754b377b35eae4192bp@chr12:12537737..12537747, +
2.39e-66FFCP PHASE2:Hg19::chr2:28148771..28148776,-#_0ad0d3a1cbd7bc754b377b35eae4192bp@chr2:28148771..28148776, -
2.39e-66FFCP PHASE1:Hg19::chr12:12537737..12537747,+#_0ad0d3a1cbd7bc754b377b35eae4192bp@chr12:12537737..12537747, +
2.39e-66FFCP PHASE2:Hg19::chr7:128630152..128630186,-#_0ad0d3a1cbd7bc754b377b35eae4192bp@chr7:128630152..128630186, -
2.39e-66FFCP PHASE2:Hg19::chr1:154720840..154720844,-#_0ad0d3a1cbd7bc754b377b35eae4192bp@chr1:154720840..154720844, -
2.39e-66FFCP PHASE2:Hg19::chr1:212101868..212101870,+#_0ad0d3a1cbd7bc754b377b35eae4192bp@chr1:212101868..212101870, +
2.39e-66FFCP PHASE2:Hg19::chr1:30128875..30128876,+#_0ad0d3a1cbd7bc754b377b35eae4192bp@chr1:30128875..30128876, +
2.39e-66FFCP PHASE2:Hg19::chr1:33608559..33608582,+#_0ad0d3a1cbd7bc754b377b35eae4192bp@chr1:33608559..33608582, +
2.39e-66FFCP PHASE2:Hg19::chr5:171595590..171595593,+#_0ad0d3a1cbd7bc754b377b35eae4192bp@chr5:171595590..171595593, +
2.39e-66FFCP PHASE2:Hg19::chr18:50772425..50772426,+#_0ad0d3a1cbd7bc754b377b35eae4192bp@chr18:50772425..50772426, +
2.39e-66FFCP PHASE2:Hg19::chr19:14467251..14467255,-#_0ad0d3a1cbd7bc754b377b35eae4192bp@chr19:14467251..14467255, -
2.39e-66FFCP PHASE2:Hg19::chr15:26341798..26341807,-#_0ad0d3a1cbd7bc754b377b35eae4192bp@chr15:26341798..26341807, -
2.39e-66FFCP PHASE1:Hg19::chrX:119444947..119444949,+#_0ad0d3a1cbd7bc754b377b35eae4192bp@chrX:119444947..119444949, +
2.39e-66FFCP PHASE1:Hg19::chrX:51490163..51490164,-#_0ad0d3a1cbd7bc754b377b35eae4192bp@chrX:51490163..51490164, -
2.39e-66FFCP PHASE2:Hg19::chr4:3371692..3371695,-#_0ad0d3a1cbd7bc754b377b35eae4192bp@chr4:3371692..3371695, -
2.39e-66FFCP PHASE2:Hg19::chr4:3946864..3946865,+#_0ad0d3a1cbd7bc754b377b35eae4192bp@chr4:3946864..3946865, +
2.39e-66FFCP PHASE2:Hg19::chr4:47477113..47477121,+#_0ad0d3a1cbd7bc754b377b35eae4192bp@chr4:47477113..47477121, +
2.39e-66FFCP PHASE2:Hg19::chr4:47477135..47477138,+#_0ad0d3a1cbd7bc754b377b35eae4192bp@chr4:47477135..47477138, +
2.39e-66FFCP PHASE2:Hg19::chr16:86052259..86052261,-#_0ad0d3a1cbd7bc754b377b35eae4192bp@chr16:86052259..86052261, -
2.39e-66FFCP PHASE2:Hg19::chr20:809889..809897,+#_0ad0d3a1cbd7bc754b377b35eae4192bp@chr20:809889..809897, +
2.39e-66FFCP PHASE2:Hg19::chrX:119444947..119444949,+#_0ad0d3a1cbd7bc754b377b35eae4192bp@chrX:119444947..119444949, +
2.39e-66FFCP PHASE2:Hg19::chr22:25463318..25463319,-#_0ad0d3a1cbd7bc754b377b35eae4192bp@chr22:25463318..25463319, -
2.39e-66FFCP PHASE2:Hg19::chrX:51490163..51490164,-#_0ad0d3a1cbd7bc754b377b35eae4192bp@chrX:51490163..51490164, -