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CL:0000875

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Name:non-classical monocyte
Namespace:cell;;efo
Definition:"Subset of monocytes characterized by low expression of CCR2, low responsiveness to monocyte chemoattractant CCL2/MCP1, low phagocytic activity, but increased co-stimulatory activity. May also play a role in tissue repair." [GO_REF:0000031, PMID:16322748, PMID:18303997, PMID:20628149, PMID:20870168]
Synonyms: "patrolling monocyte" EXACT []
"resident monocyte" EXACT []
Comments:Markers: CCR2-CX3CCR1+ (human, mouse, rat); human: CD16+, CCR5+, CD32/FcgRII-high, MHCII+, CD86+; mouse: CD62L-Ly6C-.


Ontology association
Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.

link to ontology dataset
data


Parents

is_a:CL:0000576(monocyte)



Children


is a:CL:0002396 (CD14-low, CD16-positive monocyte)

Ontology Tree: Loaded from BioPortal


FF samples
It includes FANTOM5 samples that overlay the Cell ontology.


Human (Homo sapiens)

Mouse (Mus musculus)


Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000875 (non-classical monocyte), sorted by p-values
Analyst: Hideya Kawaji

link to source dataset
human : data
mouse : data


P-valueFFCPShort description
3.27e-147FFCP PHASE1:Hg19::chr8:144480343..144480350,-#_10f4afad32065d713da8df9482fc9195p@chr8:144480343..144480350, -
3.27e-147FFCP PHASE2:Hg19::chr8:144480343..144480350,-#_10f4afad32065d713da8df9482fc9195p@chr8:144480343..144480350, -
1.47e-146FFCP PHASE1:Hg19::chr15:22550731..22550738,+#_a7f5665d1ef30583f4388abe2936ff7dp@chr15:22550731..22550738, +
1.47e-146FFCP PHASE2:Hg19::chr15:22550731..22550738,+#_a7f5665d1ef30583f4388abe2936ff7d+, p@chr15:22550731..22550738
2.33e-118FFCP PHASE1:Hg19::chr10:43609342..43609351,+#_26a9739a0c15b051bf11b7797845a2aap@chr10:43609342..43609351, +
2.33e-118FFCP PHASE2:Hg19::chr10:43609342..43609351,+#_26a9739a0c15b051bf11b7797845a2aap@chr10:43609342..43609351, +
2.33e-118FFCP PHASE1:Hg19::chr15:22538560..22538601,-#_26a9739a0c15b051bf11b7797845a2aap@chr15:22538560..22538601, -
2.33e-118FFCP PHASE2:Hg19::chr15:22538560..22538601,-#_26a9739a0c15b051bf11b7797845a2aap@chr15:22538560..22538601, -
7.78e-118FFCP PHASE1:Hg19::chr15:22550782..22550787,+#_37f94897377b168045cb3ce25502f215p@chr15:22550782..22550787, +
7.78e-118FFCP PHASE2:Hg19::chr15:22550782..22550787,+#_37f94897377b168045cb3ce25502f215p@chr15:22550782..22550787, +
1.16e-117FFCP PHASE1:Hg19::chr7:101923267..101923278,+#_ba60fb76f89154a5e39d04bc84707d1fp@chr7:101923267..101923278, +
1.16e-117FFCP PHASE2:Hg19::chr7:101923267..101923278,+#_ba60fb76f89154a5e39d04bc84707d1fp@chr7:101923267..101923278, +
4.06e-99FFCP PHASE1:Hg19::chr10:115070193..115070207,-#_4fcc963540346e3c4a0b6b2eb4cf23f4p@chr10:115070193..115070207, -
4.06e-99FFCP PHASE2:Hg19::chr1:161519682..161519691,-#_4fcc963540346e3c4a0b6b2eb4cf23f4p7@FCGR3A
4.06e-99FFCP PHASE2:Hg19::chr10:115070193..115070207,-#_4fcc963540346e3c4a0b6b2eb4cf23f4p@chr10:115070193..115070207, -
4.06e-99FFCP PHASE1:Hg19::chr1:161519682..161519691,-#_4fcc963540346e3c4a0b6b2eb4cf23f4p7@FCGR3A
2.17e-98FFCP PHASE1:Hg19::chr15:22550810..22550816,+#_7ec7885e1be75087daf1c0a1eacad79ep@chr15:22550810..22550816, +
2.17e-98FFCP PHASE2:Hg19::chr15:22550810..22550816,+#_7ec7885e1be75087daf1c0a1eacad79ep@chr15:22550810..22550816, +
3.03e-98FFCP PHASE2:Hg19::chr17:40351201..40351230,+#_bf368cb0794b10a82988bc71491e27fdp@chr17:40351201..40351230, +
3.03e-98FFCP PHASE2:Hg19::chr10:134234820..134234825,+#_bf368cb0794b10a82988bc71491e27fdp@chr10:134234820..134234825, +
3.03e-98FFCP PHASE1:Hg19::chr10:134234820..134234825,+#_bf368cb0794b10a82988bc71491e27fdp@chr10:134234820..134234825, +
3.03e-98FFCP PHASE1:Hg19::chr17:40351201..40351230,+#_bf368cb0794b10a82988bc71491e27fdp@chr17:40351201..40351230, +
2.28e-85FFCP PHASE1:Hg19::chr15:22550722..22550726,+#_6640db1e0f300a83e7e2460829f91fd7p@chr15:22550722..22550726, +
2.28e-85FFCP PHASE2:Hg19::chr15:22550722..22550726,+#_6640db1e0f300a83e7e2460829f91fd7p@chr15:22550722..22550726, +
2.28e-85FFCP PHASE2:Hg19::chr17:47287786..47287800,-#_6640db1e0f300a83e7e2460829f91fd7p@chr17:47287786..47287800, -
2.28e-85FFCP PHASE1:Hg19::chr17:47287786..47287800,-#_6640db1e0f300a83e7e2460829f91fd7p@chr17:47287786..47287800, -
2.28e-85FFCP PHASE2:Hg19::chr7:20581331..20581339,-#_6640db1e0f300a83e7e2460829f91fd7p@chr7:20581331..20581339, -
2.28e-85FFCP PHASE2:Hg19::chr7:155055063..155055078,+#_6640db1e0f300a83e7e2460829f91fd7p@chr7:155055063..155055078, +
2.28e-85FFCP PHASE2:Hg19::chr7:20581377..20581387,-#_6640db1e0f300a83e7e2460829f91fd7p@chr7:20581377..20581387, -
2.28e-85FFCP PHASE1:Hg19::chr7:20581331..20581339,-#_6640db1e0f300a83e7e2460829f91fd7-, p@chr7:20581331..20581339
2.28e-85FFCP PHASE1:Hg19::chr12:29727591..29727616,-#_6640db1e0f300a83e7e2460829f91fd7p@chr12:29727591..29727616, -
2.28e-85FFCP PHASE2:Hg19::chr12:29727591..29727616,-#_6640db1e0f300a83e7e2460829f91fd7p@chr12:29727591..29727616, -
2.28e-85FFCP PHASE1:Hg19::chr7:20581377..20581387,-#_6640db1e0f300a83e7e2460829f91fd7p@chr7:20581377..20581387, -
2.28e-85FFCP PHASE1:Hg19::chr7:155055063..155055078,+#_6640db1e0f300a83e7e2460829f91fd7p@chr7:155055063..155055078, +
3.04e-85FFCP PHASE2:Hg19::chr16:1538765..1538796,-#_f978a64d323c9a23f82e1d9c2c5b2b6fp1@PTX4
3.04e-85FFCP PHASE1:Hg19::chr16:1538765..1538796,-#_f978a64d323c9a23f82e1d9c2c5b2b6fp1@PTX4
4.06e-85FFCP PHASE1:Hg19::chr15:75080883..75080890,+#_c28fa51f3c91aaab957447e4efe7d391p14@CSK
4.06e-85FFCP PHASE2:Hg19::chr15:75080883..75080890,+#_c28fa51f3c91aaab957447e4efe7d391p14@CSK
7.21e-85FFCP PHASE2:Hg19::chr4:2794535..2794549,-#_c9651190742648153934e0ba06587ad6p@chr4:2794535..2794549, -
7.21e-85FFCP PHASE1:Hg19::chr4:2794535..2794549,-#_c9651190742648153934e0ba06587ad6p@chr4:2794535..2794549, -
6.07e-75FFCP PHASE2:Hg19::chr9:137267629..137267639,-#_dcc5d3b12b021e189958c2ed7bc7c523p@chr9:137267629..137267639, -
6.07e-75FFCP PHASE1:Hg19::chr9:137267629..137267639,-#_dcc5d3b12b021e189958c2ed7bc7c523p@chr9:137267629..137267639, -
7.81e-75FFCP PHASE1:Hg19::chr6:31584663..31584673,-#_8ef1864bde45f5c25ed63060cab37ed4p@chr6:31584663..31584673, -
7.81e-75FFCP PHASE2:Hg19::chr6:31584663..31584673,-#_8ef1864bde45f5c25ed63060cab37ed4p@chr6:31584663..31584673, -
5.01e-67FFCP PHASE1:Hg19::chr3:101597149..101597179,+#_1db0e821783627536ffd5dea1b4a2c65p@chr3:101597149..101597179, +
5.01e-67FFCP PHASE2:Hg19::chr16:4563100..4563144,-#_1db0e821783627536ffd5dea1b4a2c65p12@C16orf5
5.01e-67FFCP PHASE2:Hg19::chr3:101597149..101597179,+#_1db0e821783627536ffd5dea1b4a2c65p@chr3:101597149..101597179, +
5.01e-67FFCP PHASE1:Hg19::chr10:114594528..114594539,-#_1db0e821783627536ffd5dea1b4a2c65p@chr10:114594528..114594539, -
5.01e-67FFCP PHASE2:Hg19::chr20:825297..825306,+#_1db0e821783627536ffd5dea1b4a2c65p7@FAM110A
5.01e-67FFCP PHASE1:Hg19::chr6:144952186..144952227,+#_1db0e821783627536ffd5dea1b4a2c65p@chr6:144952186..144952227, +
5.01e-67FFCP PHASE1:Hg19::chr20:825297..825306,+#_1db0e821783627536ffd5dea1b4a2c65p7@FAM110A
5.01e-67FFCP PHASE2:Hg19::chr10:114594528..114594539,-#_1db0e821783627536ffd5dea1b4a2c65p@chr10:114594528..114594539, -
5.01e-67FFCP PHASE1:Hg19::chr2:29337114..29337117,+#_1db0e821783627536ffd5dea1b4a2c65p21@CLIP4
5.01e-67FFCP PHASE2:Hg19::chr2:29337114..29337117,+#_1db0e821783627536ffd5dea1b4a2c65p21@CLIP4
5.01e-67FFCP PHASE2:Hg19::chr6:144952186..144952227,+#_1db0e821783627536ffd5dea1b4a2c65p@chr6:144952186..144952227, +
5.01e-67FFCP PHASE1:Hg19::chr16:4563100..4563144,-#_1db0e821783627536ffd5dea1b4a2c65p12@C16orf5
6.27e-67FFCP PHASE2:Hg19::chr11:67415202..67415246,-#_1eb841de3a8762c1013c5bfa8146d2bfp5@ACY3
6.27e-67FFCP PHASE1:Hg19::chr10:115080077..115080087,-#_1eb841de3a8762c1013c5bfa8146d2bfp@chr10:115080077..115080087, -
6.27e-67FFCP PHASE1:Hg19::chr11:67415202..67415246,-#_1eb841de3a8762c1013c5bfa8146d2bfp5@ACY3
6.27e-67FFCP PHASE2:Hg19::chr2:241906877..241906887,-#_1eb841de3a8762c1013c5bfa8146d2bfp3@LOC200772
6.27e-67FFCP PHASE2:Hg19::chr10:115080077..115080087,-#_1eb841de3a8762c1013c5bfa8146d2bfp@chr10:115080077..115080087, -
6.27e-67FFCP PHASE1:Hg19::chr2:241906877..241906887,-#_1eb841de3a8762c1013c5bfa8146d2bfp3@LOC200772
9.82e-67FFCP PHASE1:Hg19::chr19:50285177..50285181,+#_f69715357c0bbacfe5d9e3eac03e6789p@chr19:50285177..50285181, +
9.82e-67FFCP PHASE2:Hg19::chr20:827656..827661,-#_f69715357c0bbacfe5d9e3eac03e6789p@chr20:827656..827661, -
9.82e-67FFCP PHASE1:Hg19::chr20:827656..827661,-#_f69715357c0bbacfe5d9e3eac03e6789p@chr20:827656..827661, -
9.82e-67FFCP PHASE2:Hg19::chr19:50285177..50285181,+#_f69715357c0bbacfe5d9e3eac03e6789p@chr19:50285177..50285181, +
9.82e-67FFCP PHASE1:Hg19::chr2:2685878..2685892,+#_f69715357c0bbacfe5d9e3eac03e6789p@chr2:2685878..2685892, +
9.82e-67FFCP PHASE2:Hg19::chr2:2685878..2685892,+#_f69715357c0bbacfe5d9e3eac03e6789p@chr2:2685878..2685892, +
2.39e-66FFCP PHASE2:Hg19::chr5:172232848..172232850,-#_7520eb33c065d180fc24c375e67306b0-, p@chr5:172232848..172232850
2.39e-66FFCP PHASE1:Hg19::chr5:172232848..172232850,-#_7520eb33c065d180fc24c375e67306b0p@chr5:172232848..172232850, -
3.76e-66FFCP PHASE1:Hg19::chr8:56800914..56800925,+#_8398c5f2fe64ac896388d60705fa6e08p@chr8:56800914..56800925, +
3.76e-66FFCP PHASE2:Hg19::chr8:56800914..56800925,+#_8398c5f2fe64ac896388d60705fa6e08p@chr8:56800914..56800925, +
3.76e-66FFCP PHASE2:Hg19::chr2:121011117..121011127,+#_8398c5f2fe64ac896388d60705fa6e08p16@RALB
3.76e-66FFCP PHASE2:Hg19::chr17:4689735..4689745,-#_8398c5f2fe64ac896388d60705fa6e08p2@VMO1
3.76e-66FFCP PHASE1:Hg19::chr2:121011117..121011127,+#_8398c5f2fe64ac896388d60705fa6e08p16@RALB
3.76e-66FFCP PHASE1:Hg19::chr17:4689735..4689745,-#_8398c5f2fe64ac896388d60705fa6e08p2@VMO1
4.68e-66FFCP PHASE2:Hg19::chr2:241906961..241906992,+#_3a871d825844c08b452993ce16f50e5cp@chr2:241906961..241906992, +
4.68e-66FFCP PHASE1:Hg19::chr2:241906961..241906992,+#_3a871d825844c08b452993ce16f50e5cp@chr2:241906961..241906992, +
1.33e-60FFCP PHASE1:Hg19::chr14:23282256..23282282,-#_f35ffc3acfaa23f76294038ceaadad95p17@SLC7A7
1.33e-60FFCP PHASE2:Hg19::chr14:23282256..23282282,-#_f35ffc3acfaa23f76294038ceaadad95p17@SLC7A7
1.33e-60FFCP PHASE1:Hg19::chr16:1538881..1538887,+#_f35ffc3acfaa23f76294038ceaadad95p@chr16:1538881..1538887, +
1.33e-60FFCP PHASE2:Hg19::chr16:1538881..1538887,+#_f35ffc3acfaa23f76294038ceaadad95p@chr16:1538881..1538887, +
1.62e-60FFCP PHASE1:Hg19::chr5:56136714..56136717,+#_cd1e729eef9e835ef4b24b98da91ecb6p@chr5:56136714..56136717, +
1.62e-60FFCP PHASE2:Hg19::chr5:56136714..56136717,+#_cd1e729eef9e835ef4b24b98da91ecb6+, p@chr5:56136714..56136717
2.43e-60FFCP PHASE1:Hg19::chr6:144980558..144980569,+#_0cf5a92bd72b99a95e5e203dc21cb17dp30@UTRN
2.43e-60FFCP PHASE2:Hg19::chr3:50654306..50654308,-#_0cf5a92bd72b99a95e5e203dc21cb17dp@chr3:50654306..50654308, -
2.43e-60FFCP PHASE2:Hg19::chr6:144980558..144980569,+#_0cf5a92bd72b99a95e5e203dc21cb17dp30@UTRN
2.43e-60FFCP PHASE2:Hg19::chr3:50658125..50658131,+#_0cf5a92bd72b99a95e5e203dc21cb17dp@chr3:50658125..50658131, +
2.43e-60FFCP PHASE1:Hg19::chr3:50654306..50654308,-#_0cf5a92bd72b99a95e5e203dc21cb17dp@chr3:50654306..50654308, -
2.43e-60FFCP PHASE1:Hg19::chr3:50658125..50658131,+#_0cf5a92bd72b99a95e5e203dc21cb17dp@chr3:50658125..50658131, +
1.22e-59FFCP PHASE2:Hg19::chr7:2797828..2797848,-#_3324e9bfaa3adcbd86de9383df587de1p@chr7:2797828..2797848, -
1.22e-59FFCP PHASE1:Hg19::chr7:2797828..2797848,-#_3324e9bfaa3adcbd86de9383df587de1p@chr7:2797828..2797848, -
2.4e-55FFCP PHASE2:Hg19::chr19:14546214..14546245,+#_e68ab7b85940999b20e3448e4afbaee9p@chr19:14546214..14546245, +
2.4e-55FFCP PHASE1:Hg19::chr17:531709..531723,-#_e68ab7b85940999b20e3448e4afbaee9p@chr17:531709..531723, -
2.4e-55FFCP PHASE1:Hg19::chr19:14546214..14546245,+#_e68ab7b85940999b20e3448e4afbaee9p@chr19:14546214..14546245, +
2.4e-55FFCP PHASE1:Hg19::chr8:142384243..142384251,+#_e68ab7b85940999b20e3448e4afbaee9p@chr8:142384243..142384251, +
2.4e-55FFCP PHASE2:Hg19::chr17:531709..531723,-#_e68ab7b85940999b20e3448e4afbaee9p@chr17:531709..531723, -
2.4e-55FFCP PHASE2:Hg19::chr8:142384243..142384251,+#_e68ab7b85940999b20e3448e4afbaee9p@chr8:142384243..142384251, +
2.88e-55FFCP PHASE2:Hg19::chr2:86225195..86225216,-#_c5344efe978e028a1d2526995b337f96p@chr2:86225195..86225216, -
2.88e-55FFCP PHASE1:Hg19::chr2:86225195..86225216,-#_c5344efe978e028a1d2526995b337f96p@chr2:86225195..86225216, -