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CL:0002173

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Name:extraglomerular mesangial cell
Namespace:cell
Definition:"A cell that is a specialized type of pericyte providing structural support for the capillary loops of kidney. A flat, elongated cell with extensive fine cytoplasmic processes found outside the kidney glomerulus near the macula densa and bound laterally by afferent and efferent arterioles. Being phagocytic, this cell participates in the continuous turnover of the basal lamina by removing its outer portion containing residues of filtration, while the lamina is renewed on its inner surface by the endothelial cells." [GOC:tfm, http:/www.copewithcytokines.de/cope.cgi?key=Lacis%20cells, ISBN:0412046911]
Xrefs:
links:

FMA:84143

KUPO:0001033
Synonyms: "Goormaghtigh cell" EXACT []
"lacis cell" RELATED []
"polar cushion cells" EXACT []
Created by:tmeehan
Creation date:2010-08-25T02:20:55Z


Ontology association
Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.

link to ontology dataset
data


Parents

is_a:CL:0000650(mesangial cell),CL:1000500(kidney interstitial cell),CL:1000618(juxtaglomerular complex cell),CL:1001318(renal interstitial pericyte)
part_of:UBERON:0002321(extraglomerular mesangium)



Children


NA

Ontology Tree: Loaded from BioPortal


FF samples
It includes FANTOM5 samples that overlay the Cell ontology.


Human (Homo sapiens)

Mouse (Mus musculus)


Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0002173 (extraglomerular mesangial cell), sorted by p-values
Analyst: Hideya Kawaji

link to source dataset
human : data
mouse : data


P-valueFFCPShort description
2.34e-79FFCP PHASE2:Hg19::chr2:133426030..133426041,-#_3764715f1c4f5f084d92a7bed1c9bf70p@chr2:133426030..133426041, -
2.34e-79FFCP PHASE1:Hg19::chr2:133426030..133426041,-#_3764715f1c4f5f084d92a7bed1c9bf70p@chr2:133426030..133426041, -
3.49e-79FFCP PHASE1:Hg19::chr1:51791596..51791607,-#_d20190c0992240c3f7a9f66d59c51cc0p23@TTC39A
3.49e-79FFCP PHASE2:Hg19::chr1:51791596..51791607,-#_d20190c0992240c3f7a9f66d59c51cc0p23@TTC39A
2.03e-66FFCP PHASE1:Hg19::chr2:133426106..133426117,-#_cfa55f4caec5d9ebed816597fb402af2p@chr2:133426106..133426117, -
2.03e-66FFCP PHASE2:Hg19::chr2:133426106..133426117,-#_cfa55f4caec5d9ebed816597fb402af2p@chr2:133426106..133426117, -
1.46e-50FFCP PHASE1:Hg19::chr10:134535354..134535366,-#_96b6e6297e6ec14cc9436e2c231c2ec4p@chr10:134535354..134535366, -
1.46e-50FFCP PHASE1:Hg19::chr10:102495136..102495146,+#_96b6e6297e6ec14cc9436e2c231c2ec4p8@PAX2
1.46e-50FFCP PHASE2:Hg19::chr10:134535354..134535366,-#_96b6e6297e6ec14cc9436e2c231c2ec4p@chr10:134535354..134535366, -
1.46e-50FFCP PHASE2:Hg19::chr10:102495136..102495146,+#_96b6e6297e6ec14cc9436e2c231c2ec4p8@PAX2
3.11e-50FFCP PHASE1:Hg19::chr17:17480803..17480814,-#_fd98eb42c371fbab8b08d3c18015e112p19@PEMT
3.11e-50FFCP PHASE2:Hg19::chr17:17480803..17480814,-#_fd98eb42c371fbab8b08d3c18015e112p19@PEMT
4.52e-50FFCP PHASE1:Hg19::chr10:102505655..102505689,+#_c5ad551b8f0d4ac6c8ccbd0d266f1ab3p10@PAX2
4.52e-50FFCP PHASE1:Hg19::chr9:81641483..81641491,-#_c5ad551b8f0d4ac6c8ccbd0d266f1ab3p@chr9:81641483..81641491, -
4.52e-50FFCP PHASE2:Hg19::chr10:102505655..102505689,+#_c5ad551b8f0d4ac6c8ccbd0d266f1ab3p10@PAX2
4.52e-50FFCP PHASE2:Hg19::chr9:81641483..81641491,-#_c5ad551b8f0d4ac6c8ccbd0d266f1ab3p@chr9:81641483..81641491, -
8.98e-41FFCP PHASE2:Hg19::chr17:171082..171101,+#_61247ec7d7864e15f06bc923b303af47p@chr17:171082..171101, +
8.98e-41FFCP PHASE1:Hg19::chr17:171082..171101,+#_61247ec7d7864e15f06bc923b303af47p@chr17:171082..171101, +
1.1e-40FFCP PHASE2:Hg19::chr3:172384246..172384250,+#_5ac1b883d58ea400e18728864e4ec5c2p@chr3:172384246..172384250, +
1.1e-40FFCP PHASE1:Hg19::chr3:172384246..172384250,+#_5ac1b883d58ea400e18728864e4ec5c2p@chr3:172384246..172384250, +
1.64e-40FFCP PHASE2:Hg19::chr1:45087902..45087912,+#_b2f05db1f484f5359edd7a6958fdad7f+, p@chr1:45087902..45087912
1.64e-40FFCP PHASE1:Hg19::chr1:45087902..45087912,+#_b2f05db1f484f5359edd7a6958fdad7fp@chr1:45087902..45087912, +
3.68e-40FFCP PHASE2:Hg19::chr10:102505552..102505563,+#_4e283c226c145837d7a2a926519676d0p5@PAX2
3.68e-40FFCP PHASE1:Hg19::chr10:102505552..102505563,+#_4e283c226c145837d7a2a926519676d0p5@PAX2
8.2e-37FFCP PHASE1:Hg19::chr10:102505312..102505320,+#_253b2935b2fe9c92da92f42b409f7995p6@PAX2
8.2e-37FFCP PHASE2:Hg19::chr10:102505312..102505320,+#_253b2935b2fe9c92da92f42b409f7995p6@PAX2
9.84e-37FFCP PHASE2:Hg19::chr9:126131131..126131159,+#_1002acbcb22f799ea93652679bd8b735p3@CRB2
9.84e-37FFCP PHASE1:Hg19::chr9:126131131..126131159,+#_1002acbcb22f799ea93652679bd8b735p3@CRB2
6.0e-34FFCP PHASE1:Hg19::chr2:113984760..113984792,+#_77243232acb74a58ae4d96d4d2efd7edp@chr2:113984760..113984792, +
6.0e-34FFCP PHASE2:Hg19::chr2:113984760..113984792,+#_77243232acb74a58ae4d96d4d2efd7edp@chr2:113984760..113984792, +
7.05e-34FFCP PHASE2:Hg19::chr1:858638..858648,+#_80f3423ad58c25dc7649fe35077314dcp@chr1:858638..858648, +
7.05e-34FFCP PHASE2:Hg19::chr7:27164585..27164612,-#_80f3423ad58c25dc7649fe35077314dcp@chr7:27164585..27164612, -
7.05e-34FFCP PHASE1:Hg19::chr1:858638..858648,+#_80f3423ad58c25dc7649fe35077314dcp@chr1:858638..858648, +
7.05e-34FFCP PHASE1:Hg19::chr11:555661..555679,+#_80f3423ad58c25dc7649fe35077314dcp@chr11:555661..555679, +
7.05e-34FFCP PHASE2:Hg19::chr11:555661..555679,+#_80f3423ad58c25dc7649fe35077314dcp@chr11:555661..555679, +
7.05e-34FFCP PHASE1:Hg19::chr7:27164585..27164612,-#_80f3423ad58c25dc7649fe35077314dcp@chr7:27164585..27164612, -
8.39e-34FFCP PHASE1:Hg19::chr10:73848549..73848564,-#_aabbe3c334955ece794d51da167ae84fp13@SPOCK2
8.39e-34FFCP PHASE2:Hg19::chr10:73848549..73848564,-#_aabbe3c334955ece794d51da167ae84fp13@SPOCK2
1.17e-33FFCP PHASE1:Hg19::chr11:118477144..118477156,+#_0a3262603c7aaa933be8756e05e2a298p25@PHLDB1
1.17e-33FFCP PHASE2:Hg19::chr11:118477144..118477156,+#_0a3262603c7aaa933be8756e05e2a298p25@PHLDB1
3.35e-32FFCP PHASE1:Hg19::chr2:693362..693373,+#_1aa5e2159c20648a7229b31495fea1c3p@chr2:693362..693373, +
3.35e-32FFCP PHASE2:Hg19::chr2:693362..693373,+#_1aa5e2159c20648a7229b31495fea1c3p@chr2:693362..693373, +
2.54e-31FFCP PHASE1:Hg19::chrX:106146562..106146577,-#_3a48cde7f9b5f2787d1025a093a480d9p1@RIPPLY1
2.54e-31FFCP PHASE2:Hg19::chrX:106146562..106146577,-#_3a48cde7f9b5f2787d1025a093a480d9p1@RIPPLY1
8.05e-30FFCP PHASE1:Hg19::chr17:171147..171161,+#_0a006e5812b84d4f9e93df64c904b2a1p@chr17:171147..171161, +
8.05e-30FFCP PHASE2:Hg19::chr17:171147..171161,+#_0a006e5812b84d4f9e93df64c904b2a1p@chr17:171147..171161, +
2.96e-29FFCP PHASE1:Hg19::chr2:165477405..165477418,-#_e71cd3b0173ffb16bb2bae91dcc04f96-, p@chr2:165477405..165477418
2.96e-29FFCP PHASE2:Hg19::chr2:165477405..165477418,-#_e71cd3b0173ffb16bb2bae91dcc04f96p@chr2:165477405..165477418, -
4.55e-29FFCP PHASE2:Hg19::chr1:874109..874143,+#_d968e1ed08139f94a0b278c3e356d70ep@chr1:874109..874143, +
4.55e-29FFCP PHASE1:Hg19::chr1:874109..874143,+#_d968e1ed08139f94a0b278c3e356d70ep@chr1:874109..874143, +
1.43e-28FFCP PHASE1:Hg19::chr2:113999199..113999214,+#_d101b1847ff4f605f3084591a11b5d60p@chr2:113999199..113999214, +
1.43e-28FFCP PHASE2:Hg19::chr2:113999199..113999214,+#_d101b1847ff4f605f3084591a11b5d60p@chr2:113999199..113999214, +
1.83e-27FFCP PHASE2:Hg19::chr16:86604624..86604648,+#_42e184fdd230dd344833620059f4ed4fp@chr16:86604624..86604648, +
1.83e-27FFCP PHASE1:Hg19::chr16:86604624..86604648,+#_42e184fdd230dd344833620059f4ed4fp@chr16:86604624..86604648, +
1.83e-27FFCP PHASE2:Hg19::chr20:6034598..6034603,-#_42e184fdd230dd344833620059f4ed4fp7@LRRN4
1.83e-27FFCP PHASE1:Hg19::chr20:6034598..6034603,-#_42e184fdd230dd344833620059f4ed4fp7@LRRN4
2.74e-27FFCP PHASE2:Hg19::chr19:56091499..56091517,-#_6012ed948a39ca5683cb7de0a19ec9a8-, p@chr19:56091499..56091517
2.74e-27FFCP PHASE1:Hg19::chr19:56091499..56091517,-#_6012ed948a39ca5683cb7de0a19ec9a8p@chr19:56091499..56091517, -
2.78e-26FFCP PHASE2:Hg19::chr9:112260040..112260045,+#_e0b347159e504a1adc20f612f4aa6a78p@chr9:112260040..112260045, +
2.78e-26FFCP PHASE1:Hg19::chr9:112260040..112260045,+#_e0b347159e504a1adc20f612f4aa6a78p@chr9:112260040..112260045, +
4.63e-26FFCP PHASE2:Hg19::chr22:30645170..30645182,-#_52c1ca6a071b83ee28284b9e849b4e21p@chr22:30645170..30645182, -
4.63e-26FFCP PHASE1:Hg19::chr22:30645170..30645182,-#_52c1ca6a071b83ee28284b9e849b4e21p@chr22:30645170..30645182, -
7.14e-26FFCP PHASE1:Hg19::chr8:22419319..22419327,+#_2fa1dde28ec441490f83b2953be374b8p@chr8:22419319..22419327, +
7.14e-26FFCP PHASE2:Hg19::chr8:22419319..22419327,+#_2fa1dde28ec441490f83b2953be374b8p@chr8:22419319..22419327, +
9.18e-26FFCP PHASE2:Hg19::chr6:31833005..31833017,-#_37a191799dfd6be7f3426889dca2075ap@chr6:31833005..31833017, -
9.18e-26FFCP PHASE1:Hg19::chr10:102505946..102505949,+#_37a191799dfd6be7f3426889dca2075ap14@PAX2
9.18e-26FFCP PHASE2:Hg19::chr2:176973165..176973169,-#_37a191799dfd6be7f3426889dca2075ap@chr2:176973165..176973169, -
9.18e-26FFCP PHASE1:Hg19::chr11:32457397..32457404,-#_37a191799dfd6be7f3426889dca2075ap15@WT1
9.18e-26FFCP PHASE2:Hg19::chr17:15555143..15555150,-#_37a191799dfd6be7f3426889dca2075ap12@TRIM16
9.18e-26FFCP PHASE2:Hg19::chr11:32457397..32457404,-#_37a191799dfd6be7f3426889dca2075ap15@WT1
9.18e-26FFCP PHASE1:Hg19::chr6:31833005..31833017,-#_37a191799dfd6be7f3426889dca2075ap@chr6:31833005..31833017, -
9.18e-26FFCP PHASE1:Hg19::chr17:15555143..15555150,-#_37a191799dfd6be7f3426889dca2075ap12@TRIM16
9.18e-26FFCP PHASE2:Hg19::chr20:6031540..6031548,-#_37a191799dfd6be7f3426889dca2075ap@chr20:6031540..6031548, -
9.18e-26FFCP PHASE2:Hg19::chr10:102505946..102505949,+#_37a191799dfd6be7f3426889dca2075ap14@PAX2
9.18e-26FFCP PHASE1:Hg19::chr2:176973165..176973169,-#_37a191799dfd6be7f3426889dca2075ap@chr2:176973165..176973169, -
9.18e-26FFCP PHASE1:Hg19::chr20:6031540..6031548,-#_37a191799dfd6be7f3426889dca2075ap@chr20:6031540..6031548, -
9.18e-26FFCP PHASE1:Hg19::chr8:28196820..28196830,+#_37a191799dfd6be7f3426889dca2075ap@chr8:28196820..28196830, +
9.18e-26FFCP PHASE2:Hg19::chr8:28196820..28196830,+#_37a191799dfd6be7f3426889dca2075ap@chr8:28196820..28196830, +
2.37e-25FFCP PHASE1:Hg19::chr7:27160553..27160560,+#_c3b7d8fa0fe55052f432cb712e00eccap1@ENST00000523364, p1@uc010kux.1
2.37e-25FFCP PHASE2:Hg19::chr7:27160553..27160560,+#_c3b7d8fa0fe55052f432cb712e00eccap1@ENST00000523364, p1@uc010kux.1
4.38e-25FFCP PHASE1:Hg19::chr7:27219754..27219759,-#_7ae9e39f8b1fd46f4e6b10450b3d19bcp16@HOXA10
4.38e-25FFCP PHASE2:Hg19::chr7:27219754..27219759,-#_7ae9e39f8b1fd46f4e6b10450b3d19bcp16@HOXA10
4.43e-25FFCP PHASE2:Hg19::chr1:149908263..149908281,-#_afb251e2fb88ff012a0ed30a437a6d13p6@MTMR11
4.43e-25FFCP PHASE1:Hg19::chr1:149908263..149908281,-#_afb251e2fb88ff012a0ed30a437a6d13p6@MTMR11
7.09e-25FFCP PHASE1:Hg19::chr10:102495147..102495159,+#_d50a1efd619edc1342dddb1de4b93879p4@PAX2
7.09e-25FFCP PHASE2:Hg19::chr10:102495147..102495159,+#_d50a1efd619edc1342dddb1de4b93879p4@PAX2
3.76e-24FFCP PHASE1:Hg19::chr1:46797583..46797614,-#_9be0a028b1b2ca22e54ac0d9251769e3p@chr1:46797583..46797614, -
3.76e-24FFCP PHASE2:Hg19::chr1:46797583..46797614,-#_9be0a028b1b2ca22e54ac0d9251769e3p@chr1:46797583..46797614, -
7.62e-24FFCP PHASE2:Hg19::chr6:94129519..94129544,+#_c296944bb2e68a1665946c710d0f8b82p@chr6:94129519..94129544, +
7.62e-24FFCP PHASE1:Hg19::chr6:94129519..94129544,+#_c296944bb2e68a1665946c710d0f8b82p@chr6:94129519..94129544, +
8.02e-24FFCP PHASE1:Hg19::chr2:693380..693398,+#_081e9097c9db1dc1042637950ae774f0p@chr2:693380..693398, +
8.02e-24FFCP PHASE2:Hg19::chr2:693380..693398,+#_081e9097c9db1dc1042637950ae774f0p@chr2:693380..693398, +
8.98e-24FFCP PHASE2:Hg19::chr2:133426077..133426103,-#_1ae11a3ac6c07c2a594ab8abd09b4eb3p@chr2:133426077..133426103, -
8.98e-24FFCP PHASE1:Hg19::chr2:133426077..133426103,-#_1ae11a3ac6c07c2a594ab8abd09b4eb3p@chr2:133426077..133426103, -
1.99e-23FFCP PHASE1:Hg19::chr11:32457350..32457361,+#_49a80d3123879651e3de7b23765ae4aep5@WT1-AS
1.99e-23FFCP PHASE2:Hg19::chr11:32457350..32457361,+#_49a80d3123879651e3de7b23765ae4aep5@WT1-AS
4.37e-23FFCP PHASE2:Hg19::chr2:176968471..176968476,-#_4c00a9963a761cbe1ecb96de86696835p@chr2:176968471..176968476, -
4.37e-23FFCP PHASE1:Hg19::chr2:176968471..176968476,-#_4c00a9963a761cbe1ecb96de86696835p@chr2:176968471..176968476, -
4.89e-23FFCP PHASE2:Hg19::chr12:15592437..15592438,+#_620604ff6d6f0e9bb31bc43d4c587884p1@ENST00000469884
4.89e-23FFCP PHASE1:Hg19::chr12:15592437..15592438,+#_620604ff6d6f0e9bb31bc43d4c587884p1@ENST00000469884