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Coexpression cluster:C1023

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Full id: C1023_seminal_ductus_thyroid_pituitary_throat_small_epididymis



Phase1 CAGE Peaks

  Short description
Hg19::chr12:97856575..97856589,+ p@chr12:97856575..97856589
+
Hg19::chr12:97856596..97856615,+ p@chr12:97856596..97856615
+
Hg19::chr12:97856637..97856647,+ p@chr12:97856637..97856647
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Hg19::chr12:97869376..97869380,+ p@chr12:97869376..97869380
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Hg19::chr12:97874189..97874200,+ p@chr12:97874189..97874200
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Hg19::chr12:97904646..97904653,+ p@chr12:97904646..97904653
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Hg19::chr12:97926446..97926450,+ p@chr12:97926446..97926450
+
Hg19::chr12:97955435..97955440,+ p@chr12:97955435..97955440
+


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression clusterSummary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner

link to source dataset
data


No GOStat results

Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset

cell_data
uberon_data


Uber Anatomy
Ontology termp-valuen
neural tube1.62e-4456
neural rod1.62e-4456
future spinal cord1.62e-4456
neural keel1.62e-4456
adult organism1.46e-39114
regional part of nervous system4.63e-3953
regional part of brain4.63e-3953
neural plate5.47e-3982
presumptive neural plate5.47e-3982
neurectoderm1.34e-3686
central nervous system2.11e-3681
nervous system2.88e-3389
regional part of forebrain1.39e-3141
forebrain1.39e-3141
anterior neural tube1.39e-3141
future forebrain1.39e-3141
brain1.89e-3168
future brain1.89e-3168
ecto-epithelium8.98e-30104
pre-chordal neural plate1.65e-2861
brain grey matter2.46e-2534
gray matter2.46e-2534
telencephalon1.25e-2434
cerebral hemisphere4.05e-2432
structure with developmental contribution from neural crest1.39e-23132
regional part of telencephalon7.75e-2232
ectoderm-derived structure6.93e-21171
ectoderm6.93e-21171
presumptive ectoderm6.93e-21171
regional part of cerebral cortex3.00e-1922
cerebral cortex8.32e-1925
pallium8.32e-1925
neocortex8.68e-1920
brainstem4.40e-146
organ system subdivision5.31e-14223
posterior neural tube8.98e-1415
chordal neural plate8.98e-1415
parietal lobe1.08e-105
gland of diencephalon2.57e-104
neuroendocrine gland2.57e-104
anatomical cluster2.74e-10373
gyrus1.07e-086
segmental subdivision of hindbrain1.33e-0812
hindbrain1.33e-0812
presumptive hindbrain1.33e-0812
male genital duct1.40e-083
internal male genitalia1.40e-083
diencephalon1.59e-087
future diencephalon1.59e-087
tube1.78e-08192
ciliary epithelium2.65e-083
ciliary body2.65e-083
anatomical conduit4.54e-08240
neural nucleus5.78e-089
nucleus of brain5.78e-089
spinal cord6.38e-083
dorsal region element6.38e-083
dorsum6.38e-083
pons6.83e-083
medulla oblongata7.32e-083
myelencephalon7.32e-083
future myelencephalon7.32e-083
segmental subdivision of nervous system7.59e-0813
male reproductive organ4.47e-0711
multi-tissue structure6.44e-07342


Overrepresented TFBS (DNA) motifs on this co-expression clusterSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.00101002
MA0004.10.455723
MA0006.10.300178
MA0007.11.1148
MA0009.10.918715
MA0014.10.00962431
MA0017.10.337901
MA0019.10.602411
MA0024.10.813542
MA0025.11.05265
MA0027.12.5321
MA0028.10.315574
MA0029.10.832916
MA0030.10.821423
MA0031.10.756713
MA0038.10.557409
MA0040.10.838784
MA0041.10.474018
MA0042.10.442535
MA0043.10.919032
MA0046.10.90778
MA0048.10.0955945
MA0050.10.443405
MA0051.10.553205
MA0052.10.842664
MA0055.10.118169
MA0056.10
MA0057.10.0912556
MA0058.10.362328
MA0059.10.361075
MA0060.10.190336
MA0061.10.165998
MA0063.10
MA0066.10.557833
MA0067.11.23721
MA0068.10.133123
MA0069.10.903908
MA0070.10.892666
MA0071.10.518907
MA0072.10.888148
MA0073.19.20286e-05
MA0074.10.552456
MA0076.10.377799
MA0077.12.04187
MA0078.10.652193
MA0081.10.361233
MA0083.10.926258
MA0084.11.42483
MA0087.10.885691
MA0088.10.441522
MA0089.10
MA0090.10.391903
MA0091.10.458301
MA0092.10.421159
MA0093.10.303084
MA0095.10
MA0098.10
MA0100.10.571227
MA0101.10.30624
MA0103.10.291333
MA0105.10.279181
MA0106.10.59853
MA0107.10.236528
MA0108.20.753643
MA0109.10
MA0111.10.405141
MA0113.10.614917
MA0114.10.231781
MA0115.11.1606
MA0116.10.239768
MA0117.10.956472
MA0119.10.345493
MA0122.10.982472
MA0124.11.11898
MA0125.11.0347
MA0130.10
MA0131.10.670358
MA0132.10
MA0133.10
MA0135.10.949204
MA0136.10.564434
MA0139.10.155155
MA0140.10.516266
MA0141.10.359385
MA0142.11.72156
MA0143.11.49284
MA0144.10.218541
MA0145.10.0613434
MA0146.10.00761723
MA0147.10.243042
MA0148.11.20731
MA0149.10.506665
MA0062.20.161302
MA0035.20.515566
MA0039.20.00133745
MA0138.20.653421
MA0002.20.179788
MA0137.20.321796
MA0104.20.189646
MA0047.20.586412
MA0112.20.0572179
MA0065.20.226158
MA0150.10.386144
MA0151.10
MA0152.10.52279
MA0153.11.01778
MA0154.10.0799828
MA0155.10.0535085
MA0156.10.323987
MA0157.10.697424
MA0158.10
MA0159.10.243637
MA0160.10.495355
MA0161.10
MA0162.10.0163939
MA0163.10.0104024
MA0164.10.627336
MA0080.20.818924
MA0018.20.599912
MA0099.20.523145
MA0079.21.80475e-05
MA0102.21.46209
MA0258.10.209744
MA0259.10.25092
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysisSummary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner

link to source dataset

data


(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
NR3C1#290835.614883749189890.01292443946090990.0464620519364579
ZZZ3#26009259.85330310880830.0004797998935036410.00436724952742084



Relative expression of the co-expression clusterSummary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.
Analyst:NA

link to data source
data


This analysis result is provided for C0 - C305 clusters.