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Coexpression cluster:C1493

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Full id: C1493_clear_thyroid_endometrioid_serous_throat_anaplastic_renal



Phase1 CAGE Peaks

  Short description
Hg19::chr2:113982484..113982512,- p@chr2:113982484..113982512
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Hg19::chr2:113982581..113982590,- p@chr2:113982581..113982590
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Hg19::chr2:113982635..113982648,- p8@PAX8
Hg19::chr2:113994209..113994222,- p11@PAX8
Hg19::chr2:114002042..114002053,- p@chr2:114002042..114002053
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Hg19::chr2:114002106..114002117,- p@chr2:114002106..114002117
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Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression clusterSummary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner

link to source dataset
data


No GOStat results

Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset

cell_data
uberon_data
disease_data


Uber Anatomy
Ontology termp-valuen
cavitated compound organ4.68e-2431
kidney4.02e-2226
kidney mesenchyme4.02e-2226
upper urinary tract4.02e-2226
kidney rudiment4.02e-2226
kidney field4.02e-2226
nephron tubule epithelium1.07e-1710
urinary system structure1.28e-1447
renal system3.05e-1448
excretory tube5.96e-1416
kidney epithelium5.96e-1416
internal genitalia8.94e-1425
thyroid gland3.21e-135
pharyngeal pouch3.21e-135
thyroid diverticulum3.21e-135
pharyngeal pouch 23.21e-135
thyroid primordium3.21e-135
male genital duct1.39e-123
internal male genitalia1.39e-123
reproductive organ1.54e-1248
renal cortex tubule4.56e-123
region of nephron tubule4.56e-123
proximal tubule4.56e-123
nephron epithelium1.82e-1115
renal tubule1.82e-1115
nephron tubule1.82e-1115
nephron1.82e-1115
uriniferous tubule1.82e-1115
nephrogenic mesenchyme1.82e-1115
reproductive structure4.18e-1159
reproductive system4.18e-1159
female reproductive organ2.77e-1037
female reproductive system2.77e-1037
embryonic uterus5.31e-1022
duct of male reproductive system1.53e-094
abdomen element3.89e-0954
abdominal segment element3.89e-0954
compound organ4.47e-0968
female organism4.62e-0941
throat8.00e-092
uterus3.28e-0821
abdominal segment of trunk6.02e-0860
abdomen6.02e-0860
internal female genitalia8.63e-0822
cortex of kidney1.06e-0712
renal parenchyma1.06e-0712


Overrepresented TFBS (DNA) motifs on this co-expression clusterSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.0799681
MA0004.10.558729
MA0006.10.391183
MA0007.10.539222
MA0009.11.03681
MA0014.10.0254709
MA0017.10.432438
MA0019.10.7124
MA0024.10.929647
MA0025.11.17262
MA0027.12.65688
MA0028.10.408079
MA0029.10.949428
MA0030.10.937696
MA0031.10.871496
MA0038.10.665566
MA0040.10.955415
MA0041.10.578072
MA0042.10.544748
MA0043.11.03713
MA0046.11.02569
MA0048.10.152639
MA0050.10.545671
MA0051.11.58921
MA0052.10.959373
MA0055.10.0586456
MA0056.10
MA0057.10.147053
MA0058.10.458909
MA0059.10.457555
MA0060.10.267412
MA0061.10.23892
MA0063.10
MA0066.10.66601
MA0067.11.35893
MA0068.10.199491
MA0069.11.02175
MA0070.12.30704
MA0071.10.625297
MA0072.11.00572
MA0073.10.00076337
MA0074.10.660398
MA0076.10.475586
MA0077.10.997832
MA0078.11.80244
MA0081.11.15882
MA0083.11.04447
MA0084.11.5477
MA0087.11.00322
MA0088.10.0971959
MA0089.10
MA0090.10.490736
MA0091.11.37996
MA0092.10.522012
MA0093.10.394379
MA0095.10
MA0098.10
MA0100.10.679972
MA0101.10.397846
MA0103.10.381434
MA0105.10.134725
MA0106.10.70837
MA0107.10.320267
MA0108.20.868347
MA0109.10
MA0111.10.504913
MA0113.10.725375
MA0114.10.314898
MA0115.11.28169
MA0116.10.865577
MA0117.11.07516
MA0119.10.440684
MA0122.12.49233
MA0124.11.23968
MA0125.11.15445
MA0130.10
MA0131.10.782708
MA0132.10
MA0133.10
MA0135.11.06778
MA0136.11.61362
MA0139.10.226048
MA0140.11.50842
MA0141.11.15452
MA0142.10.838805
MA0143.10.725558
MA0144.10.299851
MA0145.10.347815
MA0146.10.093337
MA0147.10.327615
MA0148.11.42897
MA0149.10.612449
MA0062.20.23336
MA0035.20.621793
MA0039.20.00570825
MA0138.20.765223
MA0002.20.255126
MA0137.20.414885
MA0104.20.26661
MA0047.20.695777
MA0112.20.680553
MA0065.20.109623
MA0150.10.484557
MA0151.10
MA0152.10.629368
MA0153.11.13732
MA0154.10.413181
MA0155.10.65596
MA0156.10.417278
MA0157.10.810597
MA0158.10
MA0159.10.328286
MA0160.10.600559
MA0161.10
MA0162.10.0383129
MA0163.10.0270301
MA0164.10.738243
MA0080.21.02158
MA0018.20.709805
MA0099.20.629739
MA0079.25.9246e-06
MA0102.21.58513
MA0258.12.19851
MA0259.10.336472
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysisSummary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner

link to source dataset

data


No analysis results for this cluster

Relative expression of the co-expression clusterSummary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.
Analyst:NA

link to data source
data


This analysis result is provided for C0 - C305 clusters.