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Coexpression cluster:C1740

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Full id: C1740_Keratinocyte_Mammary_Mallassezderived_Gingival_Small_Sebocyte_Tracheal



Phase1 CAGE Peaks

  Short description
Hg19::chr15:45940864..45940902,+ p@chr15:45940864..45940902
+
Hg19::chr2:69026957..69026966,+ p@chr2:69026957..69026966
+
Hg19::chr2:69027041..69027079,+ p@chr2:69027041..69027079
+
Hg19::chr6:106975163..106975184,+ p@chr6:106975163..106975184
+
Hg19::chr6:106975193..106975220,+ p@chr6:106975193..106975220
+


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression clusterSummary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner

link to source dataset
data


No GOStat results

Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset

cell_data
uberon_data
disease_data


Cell Type
Ontology termp-valuen
endo-epithelial cell5.30e-3242
respiratory epithelial cell3.24e-3113
general ecto-epithelial cell6.43e-2914
epithelial cell1.60e-24253
endodermal cell7.09e-2258
mammary gland epithelial cell2.30e-174
epithelial cell of tracheobronchial tree1.79e-169
epithelial cell of lower respiratory tract1.79e-169
ecto-epithelial cell1.42e-1534
gingival epithelial cell3.87e-143
epithelial cell of Malassez1.08e-133
duct epithelial cell1.66e-133
branched duct epithelial cell1.66e-133
tracheal epithelial cell1.66e-133
tracheoblast1.66e-133
bronchial epithelial cell2.86e-133
epidermal cell4.12e-129
stratified squamous epithelial cell7.37e-126
keratin accumulating cell7.37e-126
stratified epithelial cell7.37e-126
keratinizing barrier epithelial cell7.37e-126
epithelial fate stem cell7.37e-126
stratified epithelial stem cell7.37e-126
surface ectodermal cell7.37e-126
sebum secreting cell8.75e-102
epithelial cell of sweat gland8.75e-102
epithelial cell of skin gland8.75e-102
acinar cell of sebaceous gland8.75e-102
squamous epithelial cell1.27e-0963
epithelial cell of alimentary canal1.59e-0920
corneal epithelial cell4.92e-092
embryonic cell5.43e-09250
keratinocyte1.44e-085
acinar cell2.04e-085
protein secreting cell4.48e-076
ectodermal cell6.50e-0772
Uber Anatomy
Ontology termp-valuen
mammary gland2.30e-174
mammary bud2.30e-174
mammary ridge2.30e-174
mammary placode2.30e-174
gingival epithelium3.87e-143
respiratory system4.00e-1474
epithelial fold5.95e-1447
surface structure1.27e-1399
epithelial bud1.74e-1337
lower respiratory tract epithelium2.86e-133
epithelium of bronchus2.86e-133
tracheobronchial tree8.92e-1315
lower respiratory tract8.92e-1315
endoderm-derived structure3.33e-11160
endoderm3.33e-11160
presumptive endoderm3.33e-11160
jaw skeleton2.22e-104
splanchnocranium2.22e-104
respiratory tract3.16e-1054
skin gland8.75e-102
epidermis gland8.75e-102
gland of integumental system8.75e-102
sebaceous gland8.75e-102
skin sebaceous gland8.75e-102
sweat gland8.75e-102
sweat gland placode8.75e-102
sebaceous gland placode8.75e-102
trachea9.80e-107
respiratory airway9.80e-107
orifice1.44e-0936
external ectoderm1.02e-088
primary subdivision of cranial skeletal system2.20e-085
thoracic cavity element2.85e-0834
thoracic cavity2.85e-0834
head2.88e-0856
bronchus3.89e-085
mouth mucosa4.89e-0813
thoracic segment organ5.44e-0835
ectodermal placode1.83e-0731
anterior region of body3.10e-0762
craniocervical region3.10e-0762
skin epidermis4.01e-0715
outer epithelium4.01e-0715
enveloping layer of ectoderm4.01e-0715
protuberance4.77e-076
pharyngeal arch4.77e-076
embryonic head4.77e-076
mucosa5.59e-0720
Disease
Ontology termp-valuen
squamous cell carcinoma1.81e-0914


Overrepresented TFBS (DNA) motifs on this co-expression clusterSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.136928
MA0004.10.626788
MA0006.10.452993
MA0007.10.606704
MA0009.11.11255
MA0014.10.369468
MA0017.10.496101
MA0019.10.784036
MA0024.11.00439
MA0025.11.24931
MA0027.12.73598
MA0028.10.470679
MA0029.11.02437
MA0030.11.01252
MA0031.10.945567
MA0038.10.736268
MA0040.11.03042
MA0041.10.64667
MA0042.10.612397
MA0043.11.11288
MA0046.11.10134
MA0048.10.195817
MA0050.11.48918
MA0051.10.731787
MA0052.11.03442
MA0055.10.288856
MA0056.10
MA0057.10.189508
MA0058.10.523638
MA0059.10.522232
MA0060.10.321781
MA0061.10.291022
MA0063.10
MA0066.10.736721
MA0067.11.43651
MA0068.10.247962
MA0069.11.09737
MA0070.11.08584
MA0071.10.695094
MA0072.11.0812
MA0073.10.0140295
MA0074.10.730989
MA0076.10.540943
MA0077.11.07324
MA0078.10.836493
MA0081.10.522409
MA0083.11.12028
MA0084.11.62584
MA0087.11.07867
MA0088.10.412364
MA0089.10
MA0090.10.556637
MA0091.10.629594
MA0092.11.43794
MA0093.10.456342
MA0095.10
MA0098.10
MA0100.10.750974
MA0101.11.16366
MA0103.10.442769
MA0105.10.175503
MA0106.10.779931
MA0107.10.985964
MA0108.20.94238
MA0109.10
MA0111.10.5713
MA0113.10.797251
MA0114.10.372523
MA0115.11.35895
MA0116.10.382106
MA0117.11.1512
MA0119.12.17648
MA0122.11.17777
MA0124.11.31673
MA0125.14.45169
MA0130.10
MA0131.10.855546
MA0132.10
MA0133.10
MA0135.12.57792
MA0136.10.743749
MA0139.10.277033
MA0140.10.692258
MA0141.10.520334
MA0142.10.912455
MA0143.10.797437
MA0144.10.356507
MA0145.10.143698
MA0146.10.143081
MA0147.10.386018
MA0148.10.653474
MA0149.10.681935
MA0062.20.284987
MA0035.20.691506
MA0039.20.0575907
MA0138.20.837782
MA0002.20.30855
MA0137.20.47779
MA0104.20.320919
MA0047.20.767096
MA0112.20.425004
MA0065.20.146576
MA0150.10.550239
MA0151.10
MA0152.10.69926
MA0153.11.21379
MA0154.10.514087
MA0155.10.130813
MA0156.10.480289
MA0157.10.883854
MA0158.10
MA0159.10.386729
MA0160.10.669748
MA0161.10
MA0162.10.0592265
MA0163.10.0439995
MA0164.10.810347
MA0080.20.456437
MA0018.20.781393
MA0099.20.699641
MA0079.20.0198381
MA0102.21.66336
MA0258.10.345771
MA0259.10.395396
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysisSummary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner

link to source dataset

data


No analysis results for this cluster

Relative expression of the co-expression clusterSummary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.
Analyst:NA

link to data source
data


This analysis result is provided for C0 - C305 clusters.