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Coexpression cluster:C1811

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Full id: C1811_Mesenchymal_Alveolar_Pericytes_Placental_Renal_Melanocyte_Fibroblast



Phase1 CAGE Peaks

  Short description
Hg19::chr19:15236470..15236542,- p1@ILVBL
Hg19::chr19:1905365..1905411,+ p1@ADAT3
p1@SCAMP4
Hg19::chr1:11986442..11986502,- p1@KIAA2013
Hg19::chr3:50396911..50396972,- p1@TMEM115
Hg19::chr3:51705222..51705281,+ p1@TEX264


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression clusterSummary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner

link to source dataset
data


No GOStat results

Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset

cell_data
uberon_data


Uber Anatomy
Ontology termp-valuen
epithelial tube1.54e-17117
epithelial vesicle9.66e-1678
splanchnic layer of lateral plate mesoderm1.13e-1583
unilaminar epithelium1.67e-14148
vasculature2.44e-1478
vascular system2.44e-1478
cell layer8.28e-14309
mesenchyme1.71e-13160
entire embryonic mesenchyme1.71e-13160
epithelium1.88e-13306
vessel5.79e-1368
somite5.82e-1371
presomitic mesoderm5.82e-1371
presumptive segmental plate5.82e-1371
dermomyotome5.82e-1371
trunk paraxial mesoderm5.82e-1371
artery6.05e-1342
arterial blood vessel6.05e-1342
arterial system6.05e-1342
dense mesenchyme tissue8.12e-1373
multilaminar epithelium1.00e-1283
paraxial mesoderm1.29e-1272
presumptive paraxial mesoderm1.29e-1272
trunk mesenchyme1.41e-12122
epithelial tube open at both ends6.89e-1259
blood vessel6.89e-1259
blood vasculature6.89e-1259
vascular cord6.89e-1259
skeletal muscle tissue1.20e-1162
striated muscle tissue1.20e-1162
myotome1.20e-1162
circulatory system1.35e-11112
multi-cellular organism1.39e-11656
trunk2.29e-11199
cardiovascular system3.14e-11109
muscle tissue3.33e-1164
musculature3.33e-1164
musculature of body3.33e-1164
organism subdivision4.03e-11264
anatomical group1.07e-09625
multi-tissue structure1.20e-09342
anatomical system1.33e-09624
systemic artery1.67e-0933
systemic arterial system1.67e-0933
anatomical conduit1.37e-08240
anatomical cluster2.11e-08373
mesoderm8.81e-08315
mesoderm-derived structure8.81e-08315
presumptive mesoderm8.81e-08315
developing anatomical structure3.40e-07581
tube3.65e-07192
parenchyma8.16e-0715
extraembryonic membrane9.31e-0714
membranous layer9.31e-0714


Overrepresented TFBS (DNA) motifs on this co-expression clusterSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.737422
MA0004.11.51734
MA0006.10.452993
MA0007.10.606704
MA0009.11.11255
MA0014.14.38573
MA0017.10.496101
MA0019.10.784036
MA0024.11.00439
MA0025.11.24931
MA0027.12.73598
MA0028.11.18667
MA0029.11.02437
MA0030.11.01252
MA0031.10.945567
MA0038.10.736268
MA0040.11.03042
MA0041.10.64667
MA0042.10.612397
MA0043.11.11288
MA0046.11.10134
MA0048.10.195817
MA0050.10.613347
MA0051.10.731787
MA0052.11.03442
MA0055.10.0853006
MA0056.10
MA0057.10.554727
MA0058.12.23895
MA0059.10.522232
MA0060.10.321781
MA0061.10.291022
MA0063.10
MA0066.10.736721
MA0067.11.43651
MA0068.10.247962
MA0069.11.09737
MA0070.11.08584
MA0071.10.695094
MA0072.11.0812
MA0073.10.215829
MA0074.10.730989
MA0076.10.540943
MA0077.11.07324
MA0078.10.836493
MA0081.10.522409
MA0083.11.12028
MA0084.11.62584
MA0087.11.07867
MA0088.11.92154
MA0089.10
MA0090.10.556637
MA0091.10.629594
MA0092.10.588959
MA0093.11.15584
MA0095.10
MA0098.10
MA0100.10.750974
MA0101.10.459973
MA0103.10.442769
MA0105.11.00065
MA0106.10.779931
MA0107.10.378225
MA0108.20.94238
MA0109.10
MA0111.10.5713
MA0113.10.797251
MA0114.10.372523
MA0115.11.35895
MA0116.10.382106
MA0117.11.1512
MA0119.10.504689
MA0122.11.17777
MA0124.11.31673
MA0125.11.23103
MA0130.10
MA0131.10.855546
MA0132.10
MA0133.10
MA0135.11.14377
MA0136.10.743749
MA0139.10.759606
MA0140.10.692258
MA0141.11.29278
MA0142.10.912455
MA0143.10.797437
MA0144.10.356507
MA0145.10.868598
MA0146.10.946108
MA0147.10.386018
MA0148.10.653474
MA0149.10.681935
MA0062.20.284987
MA0035.20.691506
MA0039.21.92202
MA0138.20.837782
MA0002.20.30855
MA0137.20.47779
MA0104.20.858845
MA0047.20.767096
MA0112.20.425004
MA0065.20.449243
MA0150.10.550239
MA0151.10
MA0152.10.69926
MA0153.11.21379
MA0154.10.98952
MA0155.10.130813
MA0156.10.480289
MA0157.10.883854
MA0158.10
MA0159.10.386729
MA0160.10.669748
MA0161.10
MA0162.11.23503
MA0163.10.168633
MA0164.10.810347
MA0080.20.456437
MA0018.20.781393
MA0099.20.699641
MA0079.21.81596
MA0102.21.66336
MA0258.10.345771
MA0259.10.395396
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysisSummary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner

link to source dataset

data


(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
ATF3#467417.9705396208071.89252338486495e-050.000428935003888694
ELF1#199754.258097958807540.0007142416939776840.00573188015040229
HEY1#2346254.040111043105710.0009288852205177990.00674348975015004
IRF1#365957.63716375356393.84754333311872e-050.000724285468939413
MXI1#460135.976942977255580.008653004889366880.0329532955674077
MYC#460944.177825497287520.005691969036823440.0256809899013653
NRF1#489949.768223558168730.0002101297748106790.00244520819514791
PAX5#507945.335652424942260.002223389586187790.0127790757246088
SIX5#147912310.25202921327540.001832291068677690.0108494527112841
SP1#666755.69838137814090.000166391843712550.00204300467499354
TAF1#687253.343046285745290.002394600090870310.0135381171921401
YY1#752843.928936599883080.007193866269917620.029843900669868



Relative expression of the co-expression clusterSummary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.
Analyst:NA

link to data source
data


This analysis result is provided for C0 - C305 clusters.