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Coexpression cluster:C3465

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Full id: C3465_testis_ductus_liver_seminal_Hepatocyte_hepatocellular_spleen



Phase1 CAGE Peaks

  Short description
Hg19::chr14:95047725..95047742,+ p3@SERPINA5
Hg19::chr14:95047744..95047805,+ p1@SERPINA5
Hg19::chr14:95053862..95053873,+ p6@SERPINA5


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression clusterSummary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner

link to source dataset
data


No GOStat results

Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset

cell_data
uberon_data


Cell Type
Ontology termp-valuen
metabolising cell7.08e-0912
endopolyploid cell7.08e-0912
parenchymal cell7.08e-0912
polyploid cell7.08e-0912
hepatocyte7.08e-0912
Uber Anatomy
Ontology termp-valuen
adult organism4.57e-33114
anatomical cluster1.04e-13373
neural plate3.19e-1382
presumptive neural plate3.19e-1382
organ system subdivision3.39e-12223
neurectoderm4.58e-1286
neural tube1.65e-1156
neural rod1.65e-1156
future spinal cord1.65e-1156
neural keel1.65e-1156
central nervous system2.39e-1181
anatomical conduit6.58e-11240
brain9.03e-1168
future brain9.03e-1168
regional part of nervous system2.10e-1053
regional part of brain2.10e-1053
multi-tissue structure4.29e-10342
epithelium of foregut-midgut junction1.79e-0925
anatomical boundary1.79e-0925
hepatobiliary system1.79e-0925
foregut-midgut junction1.79e-0925
septum transversum1.79e-0925
ecto-epithelium2.47e-09104
digestive tract diverticulum3.20e-0923
nervous system3.46e-0989
tube4.29e-09192
organ8.77e-09503
liver9.08e-0919
digestive gland9.08e-0919
liver bud9.08e-0919
hepatic diverticulum1.52e-0822
liver primordium1.52e-0822
abdomen element4.41e-0854
abdominal segment element4.41e-0854
endocrine gland4.96e-0835
structure with developmental contribution from neural crest5.18e-08132
cell layer8.05e-08309
ectoderm-derived structure9.51e-08171
ectoderm9.51e-08171
presumptive ectoderm9.51e-08171
exocrine gland1.13e-0731
exocrine system1.13e-0731
sac1.14e-0726
endocrine system1.63e-0745
multi-cellular organism1.67e-07656
male reproductive organ1.82e-0711
pre-chordal neural plate2.50e-0761
gland2.84e-0759
regional part of forebrain3.23e-0741
forebrain3.23e-0741
anterior neural tube3.23e-0741
future forebrain3.23e-0741
primordium4.41e-07160
epithelial sac4.69e-0725
epithelium6.96e-07306


Overrepresented TFBS (DNA) motifs on this co-expression clusterSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.708947
MA0004.10.826076
MA0006.10.639288
MA0007.10.804807
MA0009.11.3275
MA0014.10.758317
MA0017.10.686276
MA0019.10.990656
MA0024.11.21731
MA0025.11.46617
MA0027.12.95767
MA0028.10.658629
MA0029.12.76791
MA0030.11.22561
MA0031.11.15713
MA0038.10.94098
MA0040.11.24388
MA0041.10.847069
MA0042.10.810843
MA0043.11.32783
MA0046.11.31611
MA0048.10.904546
MA0050.10.81185
MA0051.10.936307
MA0052.11.24796
MA0055.10.557638
MA0056.10
MA0057.10.333427
MA0058.10.716037
MA0059.10.714521
MA0060.10.492218
MA0061.14.06645
MA0063.10
MA0066.10.941452
MA0067.11.65513
MA0068.11.04561
MA0069.11.31207
MA0070.11.30033
MA0071.10.897953
MA0072.11.29561
MA0073.10.0834661
MA0074.10.935474
MA0076.10.734647
MA0077.11.28751
MA0078.11.04495
MA0081.10.714712
MA0083.11.33535
MA0084.11.84562
MA0087.11.29304
MA0088.10.257905
MA0089.10
MA0090.11.77664
MA0091.11.93651
MA0092.10.785956
MA0093.10.642957
MA0095.10
MA0098.10
MA0100.10.956299
MA0101.10.646932
MA0103.10.628063
MA0105.12.3269
MA0106.10.986396
MA0107.10.556367
MA0108.21.15387
MA0109.10
MA0111.10.767139
MA0113.12.29491
MA0114.11.35563
MA0115.11.57693
MA0116.10.560723
MA0117.11.36676
MA0119.10.695578
MA0122.11.39371
MA0124.11.53432
MA0125.11.44766
MA0130.10
MA0131.11.06461
MA0132.10
MA0133.10
MA0135.11.35921
MA0136.10.948776
MA0139.10.440097
MA0140.10.894983
MA0141.10.712476
MA0142.11.12317
MA0143.11.00455
MA0144.15.73745
MA0145.10.273764
MA0146.10.107247
MA0147.10.565108
MA0148.10.854239
MA0149.10.884158
MA0062.20.449458
MA0035.20.894194
MA0039.21.15986
MA0138.21.04628
MA0002.21.20011
MA0137.23.92311
MA0104.20.491226
MA0047.20.973066
MA0112.20.264678
MA0065.20.760954
MA0150.10.744617
MA0151.10
MA0152.10.902317
MA0153.11.43021
MA0154.11.51687
MA0155.10.711948
MA0156.10.669101
MA0157.11.09377
MA0158.10
MA0159.12.37721
MA0160.10.871361
MA0161.10
MA0162.10.149099
MA0163.10.776149
MA0164.11.01792
MA0080.20.643061
MA0018.20.987913
MA0099.20.902716
MA0079.20.481578
MA0102.21.88331
MA0258.10.519674
MA0259.10.575594
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysisSummary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner

link to source dataset

data


No analysis results for this cluster

Relative expression of the co-expression clusterSummary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.
Analyst:NA

link to data source
data


This analysis result is provided for C0 - C305 clusters.