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Coexpression cluster:C514

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Full id: C514_Lymphatic_Endothelial_mycosis_appendix_heart_CD14_migratory



Phase1 CAGE Peaks

Hg19::chr12:47053880..47053887,+p@chr12:47053880..47053887
+
Hg19::chr15:89736241..89736275,+p@chr15:89736241..89736275
+
Hg19::chr17:28534879..28534889,-p@chr17:28534879..28534889
-
Hg19::chr17:28534912..28534942,-p@chr17:28534912..28534942
-
Hg19::chr17:38179836..38179841,-p3@MED24
Hg19::chr17:45933057..45933064,-p3@SP6
Hg19::chr17:75873825..75873826,+p@chr17:75873825..75873826
+
Hg19::chr19:48613987..48613999,-p5@PLA2G4C
Hg19::chr1:169703213..169703227,-p1@SELE
Hg19::chr1:43917566..43917577,-p6@HYI
Hg19::chr4:114238344..114238353,+p58@ANK2
Hg19::chr4:38057520..38057536,-p@chr4:38057520..38057536
-
Hg19::chr4:38057595..38057624,-p@chr4:38057595..38057624
-
Hg19::chr4:38057720..38057727,-p@chr4:38057720..38057727
-
Hg19::chr6:29527501..29527515,-p1@UBD
Hg19::chr8:80680913..80680917,-p@chr8:80680913..80680917
-
Hg19::chr8:90769563..90769576,-p1@ENST00000523859
Hg19::chr8:90769801..90769825,+p4@RIPK2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0006954inflammatory response0.00647906594947299
GO:0009611response to wounding0.00983701397986704
GO:0008903hydroxypyruvate isomerase activity0.0127385733489111
GO:0006952defense response0.0127385733489111
GO:0009605response to external stimulus0.0129117202217266
GO:0046475glycerophospholipid catabolic process0.0150696823597155
GO:0047499calcium-independent phospholipase A2 activity0.0193733097010132
GO:0019369arachidonic acid metabolic process0.022599866037022
GO:0050700CARD domain binding0.0271142515575275
GO:0030274LIM domain binding0.0271142515575275
GO:0007567parturition0.0328589881048493
GO:0006950response to stress0.0363166120593536
GO:0009395phospholipid catabolic process0.045157841689947
GO:0042809vitamin D receptor binding0.048153480631656
GO:0016455RNA polymerase II transcription mediator activity0.048153480631656



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
lymphoid system4.09e-3310
lymphatic vessel4.97e-318
lymph vasculature4.97e-318
lymphatic part of lymphoid system4.97e-318
blood vessel endothelium4.49e-2318
endothelium4.49e-2318
cardiovascular system endothelium4.49e-2318
microcirculatory vessel1.05e-213
endothelium of capillary1.05e-213
capillary1.05e-213
vessel1.22e-1968
simple squamous epithelium1.12e-1822
vasculature9.72e-1778
vascular system9.72e-1778
squamous epithelium2.67e-1625
cardiovascular system8.43e-13109
circulatory system2.26e-12112
anatomical conduit2.72e-08240
epididymis4.40e-081
epithelial tube open at both ends7.49e-0859
blood vessel7.49e-0859
blood vasculature7.49e-0859
vascular cord7.49e-0859
tonsil7.59e-081
mucosa-associated lymphoid tissue7.59e-081
lymphoid tissue7.59e-081
tonsillar ring7.59e-081
splanchnic layer of lateral plate mesoderm8.08e-0883
endothelial tube2.53e-079
arterial system endothelium2.53e-079
endothelium of artery2.53e-079
anatomical cluster2.54e-07373
vein4.62e-079
venous blood vessel4.62e-079
venous system4.62e-079


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.0970947
MA0004.11.12587
MA0006.10.101986
MA0007.10.193512
MA0009.10.600198
MA0014.10.0667705
MA0017.10.395274
MA0019.10.322194
MA0024.10.50459
MA0025.10.725013
MA0027.12.18072
MA0028.10.726268
MA0029.11.29635
MA0030.10.511665
MA0031.10.454061
MA0038.10.285594
MA0040.10.527306
MA0041.10.628965
MA0042.10.573464
MA0043.10.60049
MA0046.10.590147
MA0048.10.151328
MA0050.11.09032
MA0051.11.40916
MA0052.10.530811
MA0055.10.02381
MA0056.10
MA0057.10.288482
MA0058.10.858202
MA0059.10.854645
MA0060.10.384884
MA0061.14.09063
MA0063.10
MA0066.10.779889
MA0067.10.900956
MA0068.10.0967272
MA0069.10.586593
MA0070.10.576293
MA0071.10.255111
MA0072.10.572162
MA0073.10.103805
MA0074.10.281628
MA0076.10.461922
MA0077.10.565087
MA0078.10.363755
MA0081.10.434032
MA0083.10.607144
MA0084.11.08294
MA0087.10.569916
MA0088.10.149441
MA0089.10
MA0090.10.485893
MA0091.10.208918
MA0092.11.02629
MA0093.11.67826
MA0095.10
MA0098.10
MA0100.10.296726
MA0101.12.97963
MA0103.10.320022
MA0105.11.6918
MA0106.10.319
MA0107.13.70069
MA0108.22.97079
MA0109.10
MA0111.10.170509
MA0113.10.332535
MA0114.10.495259
MA0115.10.827474
MA0116.10.0681676
MA0117.10.635078
MA0119.10.407815
MA0122.10.659244
MA0124.10.787807
MA0125.10.708116
MA0130.10
MA0131.10.379172
MA0132.10
MA0133.10
MA0135.10.628343
MA0136.11.44198
MA0139.10.123548
MA0140.10.253051
MA0141.10.139313
MA0142.10.426146
MA0143.10.332682
MA0144.11.21536
MA0145.10.00456382
MA0146.10.511463
MA0147.10.245602
MA0148.10.225411
MA0149.10.245595
MA0062.21.28792
MA0035.20.252505
MA0039.20.000450969
MA0138.20.364793
MA0002.20.357374
MA0137.20.743725
MA0104.20.383074
MA0047.20.309071
MA0112.20.295259
MA0065.20.526971
MA0150.10.157331
MA0151.10
MA0152.10.258148
MA0153.10.692238
MA0154.10.664419
MA0155.10.665536
MA0156.10.749879
MA0157.10.402372
MA0158.10
MA0159.10.527394
MA0160.10.236884
MA0161.10
MA0162.10.0022059
MA0163.10.839051
MA0164.10.342871
MA0080.21.14336
MA0018.20.320136
MA0099.20.258426
MA0079.20.156887
MA0102.21.11935
MA0258.10.196984
MA0259.10.257452
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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