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MCL coexpression mm9:819

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Phase1 CAGE Peaks

 Short description
Mm9::chr14:122873784..122873795,+p@chr14:122873784..122873795
+
Mm9::chr14:122874593..122874610,+p2@Zic2
Mm9::chr9:91255836..91255853,-p@chr9:91255836..91255853
-
Mm9::chr9:91256536..91256556,-p@chr9:91256536..91256556
-
Mm9::chr9:91256573..91256584,-p@chr9:91256573..91256584
-
Mm9::chr9:91256933..91256954,+p4@Zic4
Mm9::chr9:91257451..91257460,-p@chr9:91257451..91257460
-
Mm9::chr9:91260594..91260612,-p1@Zic1
Mm9::chr9:91260616..91260653,-p2@Zic1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0007417central nervous system development0.0206579680104003
GO:0008270zinc ion binding0.0206579680104003
GO:0003677DNA binding0.0206579680104003
GO:0046914transition metal ion binding0.0236530812754747
GO:0008589regulation of smoothened signaling pathway0.0236530812754747
GO:0003676nucleic acid binding0.0287686637232217
GO:0007399nervous system development0.0287686637232217
GO:0007224smoothened signaling pathway0.0310192156016182
GO:0048066pigmentation during development0.0310192156016182
GO:0043169cation binding0.0310192156016182
GO:0046872metal ion binding0.0311320280117044
GO:0043167ion binding0.0311320280117044
GO:0001843neural tube closure0.0311320280117044
GO:0014020primary neural tube formation0.0311320280117044
GO:0001841neural tube formation0.0311320280117044
GO:0001839neural plate morphogenesis0.0311320280117044
GO:0001838embryonic epithelial tube formation0.0311320280117044
GO:0001840neural plate development0.0311320280117044
GO:0005634nucleus0.0315723399114208
GO:0021915neural tube development0.0319372748698152
GO:0016331morphogenesis of embryonic epithelium0.0341450274207378



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
CNS neuron (sensu Vertebrata)8.26e-1523
neuroblast (sensu Vertebrata)8.26e-1523
neural cell8.55e-1243
ectodermal cell2.56e-1144
neurectodermal cell2.56e-1144
non-terminally differentiated cell2.92e-0949
neuron2.82e-0833
neuronal stem cell2.82e-0833
neuroblast2.82e-0833
electrically signaling cell2.82e-0833

Uber Anatomy
Ontology termp-valuen
neurectoderm3.23e-2364
neural plate3.23e-2364
presumptive neural plate3.23e-2364
central nervous system1.04e-2273
regional part of nervous system2.24e-2254
ectoderm-derived structure3.27e-2295
ectoderm3.27e-2295
presumptive ectoderm3.27e-2295
nervous system1.19e-2175
neural tube2.99e-2052
neural rod2.99e-2052
future spinal cord2.99e-2052
neural keel2.99e-2052
ecto-epithelium2.93e-1973
brain9.52e-1647
future brain9.52e-1647
pre-chordal neural plate4.78e-1549
regional part of brain5.04e-1546
posterior neural tube5.81e-1212
chordal neural plate5.81e-1212
structure with developmental contribution from neural crest1.57e-1192
anterior neural tube8.72e-1140
regional part of forebrain2.59e-1039
forebrain2.59e-1039
future forebrain2.59e-1039
gray matter3.68e-1034
spinal cord3.28e-076
dorsal region element3.28e-076
dorsum3.28e-076
regional part of spinal cord9.76e-075
gray matter of spinal cord9.76e-075
basal ganglion9.96e-078
nuclear complex of neuraxis9.96e-078
aggregate regional part of brain9.96e-078
collection of basal ganglia9.96e-078
cerebral subcortex9.96e-078


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.11.1827
MA0004.11.02263
MA0006.10.238555
MA0007.10.38073
MA0009.10.82278
MA0014.10.433479
MA0017.10.726051
MA0019.10.642876
MA0024.10.779446
MA0025.11.05446
MA0027.12.46647
MA0028.10.24786
MA0029.10.757957
MA0030.10.764448
MA0031.10.729293
MA0038.10.534262
MA0040.10.835181
MA0041.10.323687
MA0042.10.311486
MA0043.10.918718
MA0046.10.858391
MA0048.10.589612
MA0050.10.431976
MA0051.10.542972
MA0052.10.84317
MA0055.10.424109
MA0056.10
MA0057.17.07247
MA0058.10.823526
MA0059.10.316585
MA0060.12.21405
MA0061.12.40227
MA0063.10
MA0066.16.9773
MA0067.11.16502
MA0068.10.954794
MA0069.10.843506
MA0070.10.833895
MA0071.10.431174
MA0072.10.825495
MA0073.16.90453
MA0074.10.488775
MA0076.10.279739
MA0077.10.804033
MA0078.10.575205
MA0081.10.897217
MA0083.10.917931
MA0084.11.49188
MA0087.10.87515
MA0088.10.18495
MA0089.10
MA0090.10.362551
MA0091.10.407455
MA0092.10.362847
MA0093.10.709711
MA0095.10
MA0098.10
MA0100.10.477594
MA0101.10.324888
MA0103.10.272167
MA0105.16.26525
MA0106.10.582805
MA0107.11.35172
MA0108.20.665343
MA0109.10
MA0111.10.375908
MA0113.10.555251
MA0114.11.68389
MA0115.10.921497
MA0116.10.238371
MA0117.10.88947
MA0119.10.868953
MA0122.10.909168
MA0124.11.11203
MA0125.11.03833
MA0130.10
MA0131.10.638414
MA0132.10
MA0133.10
MA0135.10.954884
MA0136.10.508047
MA0139.10.143341
MA0140.10.477483
MA0141.10.29014
MA0142.10.714976
MA0143.10.571221
MA0144.10.195095
MA0145.10.200183
MA0146.10.30073
MA0147.10.205697
MA0148.10.410398
MA0149.10.330018
MA0062.20.113962
MA0035.20.482026
MA0039.20.834829
MA0138.20.630612
MA0002.20.145685
MA0137.20.287486
MA0104.20.926067
MA0047.20.533516
MA0112.22.18867
MA0065.22.19286
MA0150.10.380623
MA0151.10
MA0152.10.53362
MA0153.10.971406
MA0154.10.0809407
MA0155.10.0631765
MA0156.10.278949
MA0157.10.683365
MA0158.10
MA0159.10.214506
MA0160.10.413266
MA0161.10
MA0162.10.875406
MA0163.11.95739
MA0164.10.508398
MA0080.20.267388
MA0018.20.51781
MA0099.20.624421
MA0079.220.8454
MA0102.21.5442
MA0258.13.06153
MA0259.11.08444
MA0442.10