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UBERON:0001043

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Name:esophagus
Namespace:FANTOM
Definition:"Tube that connects the pharynx to the stomach. In mammals, the oesophagus connects the buccal cavity with the stomach. The stratified squamous non-keratinised epithelium lining the buccal cavity is continued through the pharynx down into the oesophagus. The lowest part of the oesophagus (ca. 2 cm) is lined with gastric mucosa and covered by peritoneum. The main body of the oesophagus is lined with small, simple mucous glands. Each gland opens into the lumen by a long duct which pierces the muscularis mucosae (Wilson and Washington, 1989). A sphincter is situated at the point where the oesophagus enters the stomach to prevent gastro-oesophageal reflux, i.e. to prevent acidic gastric contents from reaching stratified epithelia of the oesophagus, where they can cause inflammation and irritation (Wilson and Washington, 1989; Brown et al., 1993)." Wikipedia:Esophagus
Xrefs:
links:

AAO:0000145
ANISEED:1235301
BTO:0000959
EFO:0000835
EHDAA2:0001285
EHDAA:2937
EMAPA:16833
EMAPA:18860
EV:0100069
FMA:7131
GAID:291
galen:Esophagus
[1]
MA:0000352
MAT:0000048
MESH:A.03.365
MIAA:0000048
ncithesaurus:Esophagus
OpenCyc:Mx4rvVj9Q5wpEbGdrcN5Y29ycA
SCTID:181245004
TAO:0000204
VHOG:0000450
XAO:0000127

ZFA:0000204
Synonyms: "gullet" EXACT []
"oesophagus" EXACT []
"��ソス驛スophagus" RELATED LATIN [Wikipedia:Esophagus]
Comments:esophagus NOT part of gut in MA. part of gut in ZFA. part_of gut (via UGIT) in FMA. Consider splitting. Interspecies: The human oesophagus is 25 cm long and has a diameter of ca. 2 cm. Only little information was found on the oesophagus in rat, rabbit and pig. The oesophagus of rat (75 x 2 mm) and rabbit has no mucous glands and the cardia of the stomach has a well-developed sphincter, which prevents them from vomiting (Hebel and Stromberg, 1988; Manning et al., 1994). Morphologically the oesophagus is similar in man and pig; both are omnivores and have a non-keratinised epithelium, submucous glands and similar membrane enzymes. Like in humans, pigs can suffer from reflux oesophagitis and stress ulceration of the oesophagus. The pig oesophagus may therefore be a good model for investigation compared to the human oesophagus (Christie et al., 1995)
Alt_id: UBERON:FBbt_00005381-FMA_7131-MA_0000352-MIAA_0000048-XAO_0000127-ZFA_0000204
Subset: major_organ
organ_slim
uberon_slim
vertebrate_core

Ontology association
Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.

link to ontology dataset
data


Parents

is_a:UBERON:0004921(subdivision of digestive tract),UBERON:0005178(thoracic cavity element),UBERON:0013765(digestive system element)
develops_from:UBERON:0001041(foregut)
part_of:UBERON:0004908(upper digestive tract)



Children

is a:FF:0102817 (esophageal cancer cell line)
derives from:FF:0010015 (human esophagus - adult sample)
part of:CL:0002252 (epithelial cell of esophagus),CL:0002599 (smooth muscle cell of the esophagus)

Ontology Tree: Loaded from BioPortal


FF samples
It includes FANTOM5 samples that overlay the Uberon ontology


Human (Homo sapiens)

... further results


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0001043 (esophagus), sorted by p-values
Analyst: Hideya Kawaji

link to source dataset
human : data
mouse : data


P-valueFFCPShort description
2.39e-66FFCP PHASE2:Hg19::chr12:9010623..9010637,+#_3fa8eaf43b112bf508a1d850ddaa1a07+, p@chr12:9010623..9010637
2.39e-66FFCP PHASE1:Hg19::chr1:118570971..118570976,-#_3fa8eaf43b112bf508a1d850ddaa1a07p@chr1:118570971..118570976, -
2.39e-66FFCP PHASE1:Hg19::chr12:53200931..53200932,-#_3fa8eaf43b112bf508a1d850ddaa1a07p@chr12:53200931..53200932, -
2.39e-66FFCP PHASE1:Hg19::chr12:8995874..8995875,+#_3fa8eaf43b112bf508a1d850ddaa1a07p26@A2ML1
2.39e-66FFCP PHASE1:Hg19::chr12:53202541..53202544,-#_3fa8eaf43b112bf508a1d850ddaa1a07p@chr12:53202541..53202544, -
2.39e-66FFCP PHASE2:Hg19::chr12:53200931..53200932,-#_3fa8eaf43b112bf508a1d850ddaa1a07p@chr12:53200931..53200932, -
2.39e-66FFCP PHASE2:Hg19::chr12:53202541..53202544,-#_3fa8eaf43b112bf508a1d850ddaa1a07p@chr12:53202541..53202544, -
2.39e-66FFCP PHASE2:Hg19::chr1:118570971..118570976,-#_3fa8eaf43b112bf508a1d850ddaa1a07p@chr1:118570971..118570976, -
2.39e-66FFCP PHASE1:Hg19::chr12:9008112..9008120,+#_3fa8eaf43b112bf508a1d850ddaa1a07p25@A2ML1
2.39e-66FFCP PHASE1:Hg19::chr12:9010623..9010637,+#_3fa8eaf43b112bf508a1d850ddaa1a07p@chr12:9010623..9010637, +
2.39e-66FFCP PHASE2:Hg19::chr12:8995874..8995875,+#_3fa8eaf43b112bf508a1d850ddaa1a07p26@A2ML1
2.39e-66FFCP PHASE2:Hg19::chr7:46193488..46193497,+#_3fa8eaf43b112bf508a1d850ddaa1a07p@chr7:46193488..46193497, +
2.39e-66FFCP PHASE1:Hg19::chr12:53201644..53201647,-#_3fa8eaf43b112bf508a1d850ddaa1a07p18@KRT4
2.39e-66FFCP PHASE1:Hg19::chr7:46193488..46193497,+#_3fa8eaf43b112bf508a1d850ddaa1a07p@chr7:46193488..46193497, +
2.39e-66FFCP PHASE2:Hg19::chr12:9008112..9008120,+#_3fa8eaf43b112bf508a1d850ddaa1a07p25@A2ML1
2.39e-66FFCP PHASE2:Hg19::chr12:53201644..53201647,-#_3fa8eaf43b112bf508a1d850ddaa1a07p18@KRT4
1.28e-53FFCP PHASE2:Hg19::chr10:105495838..105495848,-#_8773a9e3560d6f599e472f40fcf63c16p@chr10:105495838..105495848, -
1.28e-53FFCP PHASE1:Hg19::chr10:105495838..105495848,-#_8773a9e3560d6f599e472f40fcf63c16p@chr10:105495838..105495848, -
3.94e-34FFCP PHASE2:Hg19::chr11:8795787..8795804,-#_8ae68dc71e3a043ad23ca34958d45c53p26@ST5
3.94e-34FFCP PHASE1:Hg19::chr11:8795787..8795804,-#_8ae68dc71e3a043ad23ca34958d45c53p26@ST5
4.27e-34FFCP PHASE2:Hg19::chr18:29006862..29006869,-#_321618ec4a15cc7539d68a4c0fcdd7e5-, p@chr18:29006862..29006869
4.27e-34FFCP PHASE2:Hg19::chr14:80697396..80697402,-#_321618ec4a15cc7539d68a4c0fcdd7e5p25@DIO2
4.27e-34FFCP PHASE1:Hg19::chr8:126017792..126017808,+#_321618ec4a15cc7539d68a4c0fcdd7e5p15@SQLE
4.27e-34FFCP PHASE1:Hg19::chr15:90030191..90030200,-#_321618ec4a15cc7539d68a4c0fcdd7e5p@chr15:90030191..90030200, -
4.27e-34FFCP PHASE1:Hg19::chr6:31023284..31023287,-#_321618ec4a15cc7539d68a4c0fcdd7e5p@chr6:31023284..31023287, -
4.27e-34FFCP PHASE2:Hg19::chr17:39659243..39659248,+#_321618ec4a15cc7539d68a4c0fcdd7e5p@chr17:39659243..39659248, +
4.27e-34FFCP PHASE2:Hg19::chr6:30954191..30954198,-#_321618ec4a15cc7539d68a4c0fcdd7e5p@chr6:30954191..30954198, -
4.27e-34FFCP PHASE1:Hg19::chr16:70602961..70602972,+#_321618ec4a15cc7539d68a4c0fcdd7e5p@chr16:70602961..70602972, +
4.27e-34FFCP PHASE2:Hg19::chr6:30954100..30954103,+#_321618ec4a15cc7539d68a4c0fcdd7e5p10@MUC21
4.27e-34FFCP PHASE1:Hg19::chr3:259245..259270,+#_321618ec4a15cc7539d68a4c0fcdd7e5p19@CHL1
4.27e-34FFCP PHASE1:Hg19::chr7:75926905..75926913,-#_321618ec4a15cc7539d68a4c0fcdd7e5p@chr7:75926905..75926913, -
4.27e-34FFCP PHASE2:Hg19::chr7:75926905..75926913,-#_321618ec4a15cc7539d68a4c0fcdd7e5p@chr7:75926905..75926913, -
4.27e-34FFCP PHASE1:Hg19::chr6:30043497..30043501,-#_321618ec4a15cc7539d68a4c0fcdd7e5p4@RNF39
4.27e-34FFCP PHASE2:Hg19::chr15:90030191..90030200,-#_321618ec4a15cc7539d68a4c0fcdd7e5p@chr15:90030191..90030200, -
4.27e-34FFCP PHASE1:Hg19::chr14:80697396..80697402,-#_321618ec4a15cc7539d68a4c0fcdd7e5p25@DIO2
4.27e-34FFCP PHASE1:Hg19::chr18:29006862..29006869,-#_321618ec4a15cc7539d68a4c0fcdd7e5p@chr18:29006862..29006869, -
4.27e-34FFCP PHASE1:Hg19::chr12:53201621..53201631,-#_321618ec4a15cc7539d68a4c0fcdd7e5p14@KRT4
4.27e-34FFCP PHASE2:Hg19::chr6:31023284..31023287,-#_321618ec4a15cc7539d68a4c0fcdd7e5p@chr6:31023284..31023287, -
4.27e-34FFCP PHASE2:Hg19::chr3:259245..259270,+#_321618ec4a15cc7539d68a4c0fcdd7e5p19@CHL1
4.27e-34FFCP PHASE1:Hg19::chr17:39659243..39659248,+#_321618ec4a15cc7539d68a4c0fcdd7e5p@chr17:39659243..39659248, +
4.27e-34FFCP PHASE1:Hg19::chr7:75927025..75927030,-#_321618ec4a15cc7539d68a4c0fcdd7e5p@chr7:75927025..75927030, -
4.27e-34FFCP PHASE2:Hg19::chr7:75927025..75927030,-#_321618ec4a15cc7539d68a4c0fcdd7e5p@chr7:75927025..75927030, -
4.27e-34FFCP PHASE2:Hg19::chr8:17611395..17611403,-#_321618ec4a15cc7539d68a4c0fcdd7e5p50@MTUS1
4.27e-34FFCP PHASE2:Hg19::chr16:70602961..70602972,+#_321618ec4a15cc7539d68a4c0fcdd7e5p@chr16:70602961..70602972, +
4.27e-34FFCP PHASE2:Hg19::chr12:53201621..53201631,-#_321618ec4a15cc7539d68a4c0fcdd7e5p14@KRT4
4.27e-34FFCP PHASE1:Hg19::chr8:17611395..17611403,-#_321618ec4a15cc7539d68a4c0fcdd7e5p50@MTUS1
4.27e-34FFCP PHASE1:Hg19::chr6:30954191..30954198,-#_321618ec4a15cc7539d68a4c0fcdd7e5p@chr6:30954191..30954198, -
4.27e-34FFCP PHASE1:Hg19::chr6:30954100..30954103,+#_321618ec4a15cc7539d68a4c0fcdd7e5p10@MUC21
4.27e-34FFCP PHASE2:Hg19::chr6:30043497..30043501,-#_321618ec4a15cc7539d68a4c0fcdd7e5p4@RNF39
4.27e-34FFCP PHASE2:Hg19::chr8:126017792..126017808,+#_321618ec4a15cc7539d68a4c0fcdd7e5p15@SQLE
4.27e-34FFCP PHASE2:Hg19::chr1:152975795..152975798,+#_321618ec4a15cc7539d68a4c0fcdd7e5p22@AB587575
4.27e-34FFCP PHASE1:Hg19::chr1:152975795..152975798,+#_321618ec4a15cc7539d68a4c0fcdd7e5p22@AB587575
5.96e-34FFCP PHASE2:Hg19::chr1:55272540..55272552,+#_77fb3204fbe1972a3a05bf6aad42c645p@chr1:55272540..55272552, +
5.96e-34FFCP PHASE2:Hg19::chr15:101069325..101069330,-#_77fb3204fbe1972a3a05bf6aad42c645p7@CERS3
5.96e-34FFCP PHASE1:Hg19::chr15:99637405..99637416,+#_77fb3204fbe1972a3a05bf6aad42c645p@chr15:99637405..99637416, +
5.96e-34FFCP PHASE1:Hg19::chr15:71839224..71839247,+#_77fb3204fbe1972a3a05bf6aad42c645p11@THSD4
5.96e-34FFCP PHASE1:Hg19::chr1:55272540..55272552,+#_77fb3204fbe1972a3a05bf6aad42c645p@chr1:55272540..55272552, +
5.96e-34FFCP PHASE1:Hg19::chr17:39657548..39657549,-#_77fb3204fbe1972a3a05bf6aad42c645p@chr17:39657548..39657549, -
5.96e-34FFCP PHASE2:Hg19::chr3:37061825..37061832,+#_77fb3204fbe1972a3a05bf6aad42c645p@chr3:37061825..37061832, +
5.96e-34FFCP PHASE2:Hg19::chr2:31476953..31476977,+#_77fb3204fbe1972a3a05bf6aad42c645p@chr2:31476953..31476977, +
5.96e-34FFCP PHASE1:Hg19::chr3:37061825..37061832,+#_77fb3204fbe1972a3a05bf6aad42c645p@chr3:37061825..37061832, +
5.96e-34FFCP PHASE2:Hg19::chr15:99637405..99637416,+#_77fb3204fbe1972a3a05bf6aad42c645p@chr15:99637405..99637416, +
5.96e-34FFCP PHASE2:Hg19::chr15:71839224..71839247,+#_77fb3204fbe1972a3a05bf6aad42c645p11@THSD4
5.96e-34FFCP PHASE2:Hg19::chr17:39657548..39657549,-#_77fb3204fbe1972a3a05bf6aad42c645p@chr17:39657548..39657549, -
5.96e-34FFCP PHASE1:Hg19::chr2:31476953..31476977,+#_77fb3204fbe1972a3a05bf6aad42c645p@chr2:31476953..31476977, +
5.96e-34FFCP PHASE1:Hg19::chr15:101069325..101069330,-#_77fb3204fbe1972a3a05bf6aad42c645p7@CERS3
1.08e-33FFCP PHASE2:Hg19::chr17:18907460..18907461,-#_4b7d0da5a1379df5bdbaf2cb45cb5fe2p12@FAM83G
1.08e-33FFCP PHASE1:Hg19::chr17:18907460..18907461,-#_4b7d0da5a1379df5bdbaf2cb45cb5fe2p12@FAM83G
2.62e-23FFCP PHASE2:Hg19::chr17:39659331..39659336,-#_284fe9f6ae29ebe07f404dd460ca7793p20@KRT13
2.62e-23FFCP PHASE1:Hg19::chr12:53201485..53201493,-#_284fe9f6ae29ebe07f404dd460ca7793p15@KRT4
2.62e-23FFCP PHASE2:Hg19::chr6:30954084..30954093,-#_284fe9f6ae29ebe07f404dd460ca7793p@chr6:30954084..30954093, -
2.62e-23FFCP PHASE1:Hg19::chr20:46821059..46821069,+#_284fe9f6ae29ebe07f404dd460ca7793+, p@chr20:46821059..46821069
2.62e-23FFCP PHASE2:Hg19::chr2:178179611..178179619,-#_284fe9f6ae29ebe07f404dd460ca7793p4@ENST00000443132
2.62e-23FFCP PHASE2:Hg19::chr11:67786884..67786893,+#_284fe9f6ae29ebe07f404dd460ca7793p2@AK129943
2.62e-23FFCP PHASE2:Hg19::chr12:53201485..53201493,-#_284fe9f6ae29ebe07f404dd460ca7793p15@KRT4
2.62e-23FFCP PHASE2:Hg19::chr1:152382640..152382645,+#_284fe9f6ae29ebe07f404dd460ca7793p@chr1:152382640..152382645, +
2.62e-23FFCP PHASE1:Hg19::chr19:51530837..51530842,-#_284fe9f6ae29ebe07f404dd460ca7793p10@KLK11
2.62e-23FFCP PHASE2:Hg19::chr1:153362896..153362903,-#_284fe9f6ae29ebe07f404dd460ca7793p5@S100A8
2.62e-23FFCP PHASE1:Hg19::chr1:152382640..152382645,+#_284fe9f6ae29ebe07f404dd460ca7793p@chr1:152382640..152382645, +
2.62e-23FFCP PHASE2:Hg19::chr3:124535316..124535340,+#_284fe9f6ae29ebe07f404dd460ca7793p@chr3:124535316..124535340, +
2.62e-23FFCP PHASE1:Hg19::chr1:153362896..153362903,-#_284fe9f6ae29ebe07f404dd460ca7793p5@S100A8
2.62e-23FFCP PHASE1:Hg19::chr18:29006845..29006854,-#_284fe9f6ae29ebe07f404dd460ca7793p@chr18:29006845..29006854, -
2.62e-23FFCP PHASE1:Hg19::chr2:178179611..178179619,-#_284fe9f6ae29ebe07f404dd460ca7793p4@ENST00000443132
2.62e-23FFCP PHASE2:Hg19::chr20:46821059..46821069,+#_284fe9f6ae29ebe07f404dd460ca7793p@chr20:46821059..46821069, +
2.62e-23FFCP PHASE1:Hg19::chr12:53232854..53232870,-#_284fe9f6ae29ebe07f404dd460ca7793p@chr12:53232854..53232870, -
2.62e-23FFCP PHASE1:Hg19::chr17:39659331..39659336,-#_284fe9f6ae29ebe07f404dd460ca7793p20@KRT13
2.62e-23FFCP PHASE1:Hg19::chr3:124535316..124535340,+#_284fe9f6ae29ebe07f404dd460ca7793p@chr3:124535316..124535340, +
2.62e-23FFCP PHASE2:Hg19::chr12:53232854..53232870,-#_284fe9f6ae29ebe07f404dd460ca7793p@chr12:53232854..53232870, -
2.62e-23FFCP PHASE1:Hg19::chr6:30954084..30954093,-#_284fe9f6ae29ebe07f404dd460ca7793p@chr6:30954084..30954093, -
2.62e-23FFCP PHASE2:Hg19::chr18:29006845..29006854,-#_284fe9f6ae29ebe07f404dd460ca7793p@chr18:29006845..29006854, -
2.62e-23FFCP PHASE1:Hg19::chr12:53673418..53673427,+#_284fe9f6ae29ebe07f404dd460ca7793p9@ESPL1
2.62e-23FFCP PHASE1:Hg19::chr11:67786884..67786893,+#_284fe9f6ae29ebe07f404dd460ca7793p2@AK129943
2.62e-23FFCP PHASE2:Hg19::chr12:53673418..53673427,+#_284fe9f6ae29ebe07f404dd460ca7793p9@ESPL1
2.62e-23FFCP PHASE2:Hg19::chr19:51530837..51530842,-#_284fe9f6ae29ebe07f404dd460ca7793p10@KLK11
3.27e-23FFCP PHASE2:Hg19::chr8:77108050..77108053,-#_8618fd1ea389a2559894397ac0380954p@chr8:77108050..77108053, -
3.27e-23FFCP PHASE1:Hg19::chr5:175837672..175837682,-#_8618fd1ea389a2559894397ac0380954p@chr5:175837672..175837682, -
3.27e-23FFCP PHASE2:Hg19::chr17:39659966..39659969,-#_8618fd1ea389a2559894397ac0380954p@chr17:39659966..39659969, -
3.27e-23FFCP PHASE1:Hg19::chr11:698049..698054,-#_8618fd1ea389a2559894397ac0380954p@chr11:698049..698054, -
3.27e-23FFCP PHASE1:Hg19::chr18:61254221..61254236,+#_8618fd1ea389a2559894397ac0380954p4@SERPINB13
3.27e-23FFCP PHASE2:Hg19::chr18:52259392..52259401,+#_8618fd1ea389a2559894397ac0380954p@chr18:52259392..52259401, +










Property "Property value" (as page type) with input value "UBPROP:0000001 "Anterior end of the alimentary canal lined with smooth muscle. Bounded anteriorly by a constriction in the pharynx. Bounded posteriorly by and increase in circular and/or longitudinal smooth muscle associated with the stomach.[AAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.