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UBERON:0003072

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Name:optic cup
Namespace:FANTOM
Definition:"Multi-tissue structure that is comprised of neural and non-neural epithelial layers which will form the retina and retinal pigmented epithelium of the mature eye[ZFA]. double walled structured formed by expansion and invagination of the distal end of the optic vesicle that develops into the pigmented and sensory layers of the retina while the mouth of the optic cup eventually forms the pupil of the eye[MP]." [MP:0004269, Optic_cup_(embryology), ZFA:0001202]
Xrefs:
links:

EHDAA2:0001303
EHDAA:2912
EMAPA:16674
ncithesaurus:Optic_Cup
SCTID:308789007
TAO:0001202
VHOG:0000167

ZFA:0001202
Synonyms: "eye cup" RELATED []
Alt_id: UBERON:XAO_0000228-ZFA_0001202
Subset: vertebrate_core

Ontology association
Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.

link to ontology dataset
data


Parents

is_a:UBERON:0000481(multi-tissue structure),UBERON:0004121(ectoderm-derived structure)
develops_from:UBERON:0004128(optic vesicle)
part_of:UBERON:0010312(immature eye)



Children

develops from:UBERON:0000019 (camera-type eye),UBERON:0000966 (retina)
part of:UBERON:0005424 (presumptive retinal pigmented epithelium),UBERON:0005425 (presumptive neural retina)

Ontology Tree: Loaded from BioPortal


FF samples
It includes FANTOM5 samples that overlay the Uberon ontology




Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0003072 (optic cup), sorted by p-values
Analyst: Hideya Kawaji

link to source dataset
human : data
mouse : data


P-valueFFCPShort description
1.31e-86FFCP PHASE1:Mm9::chr11:3622163..3622187,-#_c3cd93807b79984356f159533c771a51p8@Osbp2
1.31e-86FFCP PHASE2:Mm9::chr17:31815126..31815139,-#_c3cd93807b79984356f159533c771a51p@chr17:31815126..31815139, -
1.31e-86FFCP PHASE1:Mm9::chr2:90827760..90827769,+#_c3cd93807b79984356f159533c771a51p6@Celf1
1.31e-86FFCP PHASE1:Mm9::chr10:127668442..127668453,+#_c3cd93807b79984356f159533c771a51p@chr10:127668442..127668453, +
1.31e-86FFCP PHASE1:Mm9::chr17:31817987..31818013,+#_c3cd93807b79984356f159533c771a51p@chr17:31817987..31818013, +
1.31e-86FFCP PHASE2:Mm9::chr11:3622163..3622187,-#_c3cd93807b79984356f159533c771a51p8@Osbp2
1.31e-86FFCP PHASE1:Mm9::chr11:77532391..77532408,-#_c3cd93807b79984356f159533c771a51p@chr11:77532391..77532408, -
1.31e-86FFCP PHASE1:Mm9::chr17:31818263..31818276,+#_c3cd93807b79984356f159533c771a51p@chr17:31818263..31818276, +
1.31e-86FFCP PHASE1:Mm9::chr11:3622192..3622225,-#_c3cd93807b79984356f159533c771a51p3@Osbp2
1.31e-86FFCP PHASE2:Mm9::chr16:21743134..21743139,-#_c3cd93807b79984356f159533c771a51p@chr16:21743134..21743139, -
1.31e-86FFCP PHASE2:Mm9::chr11:77532283..77532316,-#_c3cd93807b79984356f159533c771a51p@chr11:77532283..77532316, -
1.31e-86FFCP PHASE2:Mm9::chr4:133799669..133799683,+#_c3cd93807b79984356f159533c771a51p1@E130218I03Rik
1.31e-86FFCP PHASE2:Mm9::chr3:129525389..129525400,-#_c3cd93807b79984356f159533c771a51p@chr3:129525389..129525400, -
1.31e-86FFCP PHASE2:Mm9::chr11:77532391..77532408,-#_c3cd93807b79984356f159533c771a51p@chr11:77532391..77532408, -
1.31e-86FFCP PHASE1:Mm9::chr11:77532283..77532316,-#_c3cd93807b79984356f159533c771a51p@chr11:77532283..77532316, -
1.31e-86FFCP PHASE2:Mm9::chr2:90827760..90827769,+#_c3cd93807b79984356f159533c771a51p6@Celf1
1.31e-86FFCP PHASE1:Mm9::chr17:31818106..31818119,+#_c3cd93807b79984356f159533c771a51p@chr17:31818106..31818119, +
1.31e-86FFCP PHASE2:Mm9::chr11:3622192..3622225,-#_c3cd93807b79984356f159533c771a51p3@Osbp2
1.31e-86FFCP PHASE2:Mm9::chr17:31817987..31818013,+#_c3cd93807b79984356f159533c771a51p@chr17:31817987..31818013, +
1.31e-86FFCP PHASE2:Mm9::chr14:118451218..118451221,-#_c3cd93807b79984356f159533c771a51p4@Dct
1.31e-86FFCP PHASE2:Mm9::chr10:67364011..67364018,-#_c3cd93807b79984356f159533c771a51p5@Zfp365
1.31e-86FFCP PHASE2:Mm9::chr10:127668442..127668453,+#_c3cd93807b79984356f159533c771a51p@chr10:127668442..127668453, +
1.31e-86FFCP PHASE1:Mm9::chr14:118451218..118451221,-#_c3cd93807b79984356f159533c771a51p4@Dct
1.31e-86FFCP PHASE2:Mm9::chr9:89697580..89697585,-#_c3cd93807b79984356f159533c771a51p1@Mir184
1.31e-86FFCP PHASE1:Mm9::chr17:31815126..31815139,-#_c3cd93807b79984356f159533c771a51p@chr17:31815126..31815139, -
1.31e-86FFCP PHASE2:Mm9::chr17:31818263..31818276,+#_c3cd93807b79984356f159533c771a51p@chr17:31818263..31818276, +
1.31e-86FFCP PHASE1:Mm9::chr4:133799669..133799683,+#_c3cd93807b79984356f159533c771a51p1@E130218I03Rik
1.31e-86FFCP PHASE1:Mm9::chr9:89697580..89697585,-#_c3cd93807b79984356f159533c771a51p1@Mir184
1.31e-86FFCP PHASE1:Mm9::chr3:129525389..129525400,-#_c3cd93807b79984356f159533c771a51p@chr3:129525389..129525400, -
1.31e-86FFCP PHASE2:Mm9::chr17:31818106..31818119,+#_c3cd93807b79984356f159533c771a51p@chr17:31818106..31818119, +
1.31e-86FFCP PHASE1:Mm9::chr10:67364011..67364018,-#_c3cd93807b79984356f159533c771a51p5@Zfp365
1.31e-86FFCP PHASE1:Mm9::chr16:21743134..21743139,-#_c3cd93807b79984356f159533c771a51-, p@chr16:21743134..21743139
2.3e-78FFCP PHASE2:Mm9::chr10:127668637..127668650,+#_325fdbe4da15376563fd67c152125a12p3@LOC100504989, p3@Timeless
2.3e-78FFCP PHASE2:Mm9::chr7:64675015..64675028,+#_325fdbe4da15376563fd67c152125a12p@chr7:64675015..64675028, +
2.3e-78FFCP PHASE1:Mm9::chr10:127668637..127668650,+#_325fdbe4da15376563fd67c152125a12p3@LOC100504989, p3@Timeless
2.3e-78FFCP PHASE1:Mm9::chr7:64675015..64675028,+#_325fdbe4da15376563fd67c152125a12p@chr7:64675015..64675028, +
2.82e-78FFCP PHASE2:Mm9::chr2:105509100..105509107,+#_0a2f8d1c541b0652a534636663520f9cp6@Pax6
2.82e-78FFCP PHASE2:Mm9::chr6:97891135..97891147,+#_0a2f8d1c541b0652a534636663520f9cp@chr6:97891135..97891147, +
2.82e-78FFCP PHASE1:Mm9::chr2:105509100..105509107,+#_0a2f8d1c541b0652a534636663520f9cp6@Pax6
2.82e-78FFCP PHASE1:Mm9::chr6:97891135..97891147,+#_0a2f8d1c541b0652a534636663520f9cp@chr6:97891135..97891147, +
3.46e-78FFCP PHASE1:Mm9::chr14:49498256..49498278,+#_0592175738a5acdea87c0a484e51efe1p1@4933429O19Rik
3.46e-78FFCP PHASE2:Mm9::chr14:49498256..49498278,+#_0592175738a5acdea87c0a484e51efe1p1@4933429O19Rik
4.97e-77FFCP PHASE2:Mm9::chr5:112696408..112696421,-#_022d8341b370c6ca5b1301b32de1d706p@chr5:112696408..112696421, -
4.97e-77FFCP PHASE1:Mm9::chr1:65149656..65149674,-#_022d8341b370c6ca5b1301b32de1d706p2@Cryga
4.97e-77FFCP PHASE1:Mm9::chr3:129525452..129525463,-#_022d8341b370c6ca5b1301b32de1d706p3@Rrh
4.97e-77FFCP PHASE2:Mm9::chr5:112675556..112675574,-#_022d8341b370c6ca5b1301b32de1d706p@chr5:112675556..112675574, -
4.97e-77FFCP PHASE2:Mm9::chr14:35413322..35413333,-#_022d8341b370c6ca5b1301b32de1d706p1@Opn4
4.97e-77FFCP PHASE2:Mm9::chr14:49501519..49501530,-#_022d8341b370c6ca5b1301b32de1d706p@chr14:49501519..49501530, -
4.97e-77FFCP PHASE1:Mm9::chr1:38092602..38092616,+#_022d8341b370c6ca5b1301b32de1d706p@chr1:38092602..38092616, +
4.97e-77FFCP PHASE2:Mm9::chr10:93761330..93761358,-#_022d8341b370c6ca5b1301b32de1d706p1@Gm4792
4.97e-77FFCP PHASE2:Mm9::chr5:112690729..112690741,+#_022d8341b370c6ca5b1301b32de1d706p@chr5:112690729..112690741, +
4.97e-77FFCP PHASE2:Mm9::chr5:113506190..113506202,-#_022d8341b370c6ca5b1301b32de1d706p@chr5:113506190..113506202, -
4.97e-77FFCP PHASE1:Mm9::chr3:34488839..34488876,+#_022d8341b370c6ca5b1301b32de1d706p1@ENSMUST00000173365
4.97e-77FFCP PHASE1:Mm9::chr5:112692580..112692595,+#_022d8341b370c6ca5b1301b32de1d706p@chr5:112692580..112692595, +
4.97e-77FFCP PHASE2:Mm9::chr5:112688342..112688357,+#_022d8341b370c6ca5b1301b32de1d706p@chr5:112688342..112688357, +
4.97e-77FFCP PHASE2:Mm9::chr3:129525435..129525448,-#_022d8341b370c6ca5b1301b32de1d706p2@Rrh
4.97e-77FFCP PHASE1:Mm9::chr2:93906955..93906973,-#_022d8341b370c6ca5b1301b32de1d706p2@Hsd17b12
4.97e-77FFCP PHASE2:Mm9::chr5:112681470..112681483,-#_022d8341b370c6ca5b1301b32de1d706p@chr5:112681470..112681483, -
4.97e-77FFCP PHASE1:Mm9::chr5:112688342..112688357,+#_022d8341b370c6ca5b1301b32de1d706p@chr5:112688342..112688357, +
4.97e-77FFCP PHASE2:Mm9::chr17:31818215..31818239,-#_022d8341b370c6ca5b1301b32de1d706p@chr17:31818215..31818239, -
4.97e-77FFCP PHASE2:Mm9::chr11:77532270..77532280,-#_022d8341b370c6ca5b1301b32de1d706p@chr11:77532270..77532280, -
4.97e-77FFCP PHASE1:Mm9::chr15:36655026..36655032,+#_022d8341b370c6ca5b1301b32de1d706p@chr15:36655026..36655032, +
4.97e-77FFCP PHASE1:Mm9::chr16:56204438..56204451,+#_022d8341b370c6ca5b1301b32de1d706p1@Impg2
4.97e-77FFCP PHASE2:Mm9::chr1:65147201..65147212,-#_022d8341b370c6ca5b1301b32de1d706p@chr1:65147201..65147212, -
4.97e-77FFCP PHASE1:Mm9::chr1:65146997..65147021,-#_022d8341b370c6ca5b1301b32de1d706p@chr1:65146997..65147021, -
4.97e-77FFCP PHASE1:Mm9::chr1:38092538..38092550,+#_022d8341b370c6ca5b1301b32de1d706p@chr1:38092538..38092550, +
4.97e-77FFCP PHASE1:Mm9::chr5:112690963..112690994,+#_022d8341b370c6ca5b1301b32de1d706p@chr5:112690963..112690994, +
4.97e-77FFCP PHASE1:Mm9::chr5:113506006..113506025,-#_022d8341b370c6ca5b1301b32de1d706p@chr5:113506006..113506025, -
4.97e-77FFCP PHASE2:Mm9::chr5:113506006..113506025,-#_022d8341b370c6ca5b1301b32de1d706p@chr5:113506006..113506025, -
4.97e-77FFCP PHASE2:Mm9::chr11:95705150..95705170,+#_022d8341b370c6ca5b1301b32de1d706p3@Gngt2
4.97e-77FFCP PHASE2:Mm9::chr5:112690744..112690755,+#_022d8341b370c6ca5b1301b32de1d706p@chr5:112690744..112690755, +
4.97e-77FFCP PHASE1:Mm9::chr7:28282354..28282365,+#_022d8341b370c6ca5b1301b32de1d706p@chr7:28282354..28282365, +
4.97e-77FFCP PHASE1:Mm9::chr6:85969237..85969247,+#_022d8341b370c6ca5b1301b32de1d706p@chr6:85969237..85969247, +
4.97e-77FFCP PHASE2:Mm9::chr10:127668686..127668697,+#_022d8341b370c6ca5b1301b32de1d706p4@LOC100504989, p4@Timeless
4.97e-77FFCP PHASE1:Mm9::chr1:152166537..152166579,+#_022d8341b370c6ca5b1301b32de1d706p1@Pdc
4.97e-77FFCP PHASE1:Mm9::chr10:127668480..127668491,+#_022d8341b370c6ca5b1301b32de1d706p@chr10:127668480..127668491, +
4.97e-77FFCP PHASE2:Mm9::chr3:129525452..129525463,-#_022d8341b370c6ca5b1301b32de1d706p3@Rrh
4.97e-77FFCP PHASE1:Mm9::chr11:77532270..77532280,-#_022d8341b370c6ca5b1301b32de1d706p@chr11:77532270..77532280, -
4.97e-77FFCP PHASE2:Mm9::chr7:29477874..29477889,+#_022d8341b370c6ca5b1301b32de1d706p6@Fbxo27
4.97e-77FFCP PHASE1:Mm9::chr3:129525405..129525428,-#_022d8341b370c6ca5b1301b32de1d706p1@Rrh
4.97e-77FFCP PHASE1:Mm9::chr8:77582172..77582183,+#_022d8341b370c6ca5b1301b32de1d706p@chr8:77582172..77582183, +
4.97e-77FFCP PHASE2:Mm9::chr1:152166537..152166579,+#_022d8341b370c6ca5b1301b32de1d706p1@Pdc
4.97e-77FFCP PHASE2:Mm9::chr2:93906955..93906973,-#_022d8341b370c6ca5b1301b32de1d706p2@Hsd17b12
4.97e-77FFCP PHASE2:Mm9::chr1:65147224..65147236,-#_022d8341b370c6ca5b1301b32de1d706p@chr1:65147224..65147236, -
4.97e-77FFCP PHASE2:Mm9::chr1:38092602..38092616,+#_022d8341b370c6ca5b1301b32de1d706p@chr1:38092602..38092616, +
4.97e-77FFCP PHASE2:Mm9::chr8:77582172..77582183,+#_022d8341b370c6ca5b1301b32de1d706p@chr8:77582172..77582183, +
4.97e-77FFCP PHASE2:Mm9::chr3:34488839..34488876,+#_022d8341b370c6ca5b1301b32de1d706p1@ENSMUST00000173365
4.97e-77FFCP PHASE1:Mm9::chr4:19208009..19208054,+#_022d8341b370c6ca5b1301b32de1d706p1@Cngb3
4.97e-77FFCP PHASE1:Mm9::chr6:115162924..115162933,+#_022d8341b370c6ca5b1301b32de1d706p@chr6:115162924..115162933, +
4.97e-77FFCP PHASE1:Mm9::chr14:49501519..49501530,-#_022d8341b370c6ca5b1301b32de1d706p@chr14:49501519..49501530, -
4.97e-77FFCP PHASE1:Mm9::chr14:52730585..52730607,+#_022d8341b370c6ca5b1301b32de1d706p1@Rpgrip1
4.97e-77FFCP PHASE2:Mm9::chr6:85969237..85969247,+#_022d8341b370c6ca5b1301b32de1d706p@chr6:85969237..85969247, +
4.97e-77FFCP PHASE1:Mm9::chr17:31816514..31816526,+#_022d8341b370c6ca5b1301b32de1d706p@chr17:31816514..31816526, +
4.97e-77FFCP PHASE1:Mm9::chr5:112686483..112686494,+#_022d8341b370c6ca5b1301b32de1d706p@chr5:112686483..112686494, +
4.97e-77FFCP PHASE1:Mm9::chr11:95705150..95705170,+#_022d8341b370c6ca5b1301b32de1d706p3@Gngt2
4.97e-77FFCP PHASE2:Mm9::chr14:52730585..52730607,+#_022d8341b370c6ca5b1301b32de1d706p1@Rpgrip1
4.97e-77FFCP PHASE1:Mm9::chr17:31818629..31818644,+#_022d8341b370c6ca5b1301b32de1d706p@chr17:31818629..31818644, +
4.97e-77FFCP PHASE2:Mm9::chr10:127668799..127668810,+#_022d8341b370c6ca5b1301b32de1d706p5@LOC100504989, p5@Timeless
4.97e-77FFCP PHASE1:Mm9::chr5:112696408..112696421,-#_022d8341b370c6ca5b1301b32de1d706p@chr5:112696408..112696421, -
4.97e-77FFCP PHASE2:Mm9::chr17:31817947..31817965,+#_022d8341b370c6ca5b1301b32de1d706p@chr17:31817947..31817965, +