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CL:0000623

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Name:natural killer cell
Namespace:FANTOM
Definition:"A lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors and also regulate immune responses via cytokine release and direct contact with other cells." [GOC:add, ISBN:0781735149, PMID:15771571]
Xrefs:
links:

BTO:0000914
BTO:0004716
FMA:63147

FMA:83601
Synonyms: "large granular lymphocyte" BROAD []
"NK cell" EXACT []
"null cell" BROAD []


Ontology association
Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.

link to ontology dataset
data


Parents

is_a:CL:0000542(lymphocyte)
develops_from:CL:0000825(pro-NK cell)



Children


disjoint from:CL:0000084 (T cell)
derives from:FF:0000119 (human natural killer cell sample)

Ontology Tree: Loaded from BioPortal


FF samples
It includes FANTOM5 samples that overlay the Cell ontology.


Human (Homo sapiens)

Mouse (Mus musculus)


Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000623 (natural killer cell), sorted by p-values
Analyst: Hideya Kawaji

link to source dataset
human : data
mouse : data


P-valueFFCPShort description
2.79e-195FFCP PHASE1:Hg19::chr11:115085875..115085888,+#_a428f1fa76d08f93945cd96e423756fdp@chr11:115085875..115085888, +
2.79e-195FFCP PHASE1:Hg19::chr8:103110281..103110286,+#_a428f1fa76d08f93945cd96e423756fdp@chr8:103110281..103110286, +
2.79e-195FFCP PHASE2:Hg19::chr8:103110281..103110286,+#_a428f1fa76d08f93945cd96e423756fdp@chr8:103110281..103110286, +
2.79e-195FFCP PHASE2:Hg19::chr11:115085875..115085888,+#_a428f1fa76d08f93945cd96e423756fdp@chr11:115085875..115085888, +
2.79e-195FFCP PHASE1:Hg19::chr3:4892090..4892095,-#_a428f1fa76d08f93945cd96e423756fdp@chr3:4892090..4892095, -
2.79e-195FFCP PHASE2:Hg19::chr3:4892090..4892095,-#_a428f1fa76d08f93945cd96e423756fdp@chr3:4892090..4892095, -
3.27e-147FFCP PHASE2:Hg19::chr8:103120766..103120771,+#_1a317224837b1a65b5dc279c6c28d81dp@chr8:103120766..103120771, +
3.27e-147FFCP PHASE2:Hg19::chr8:103126233..103126242,-#_1a317224837b1a65b5dc279c6c28d81dp@chr8:103126233..103126242, -
3.27e-147FFCP PHASE2:Hg19::chr8:66750085..66750091,+#_1a317224837b1a65b5dc279c6c28d81dp@chr8:66750085..66750091, +
3.27e-147FFCP PHASE2:Hg19::chr9:136007795..136007801,-#_1a317224837b1a65b5dc279c6c28d81dp@chr9:136007795..136007801, -
3.27e-147FFCP PHASE2:Hg19::chr22:38597578..38597586,-#_1a317224837b1a65b5dc279c6c28d81dp@chr22:38597578..38597586, -
3.27e-147FFCP PHASE2:Hg19::chr2:240467130..240467134,+#_1a317224837b1a65b5dc279c6c28d81dp@chr2:240467130..240467134, +
3.27e-147FFCP PHASE1:Hg19::chr8:103120766..103120771,+#_1a317224837b1a65b5dc279c6c28d81dp@chr8:103120766..103120771, +
3.27e-147FFCP PHASE1:Hg19::chr8:103126233..103126242,-#_1a317224837b1a65b5dc279c6c28d81dp@chr8:103126233..103126242, -
3.27e-147FFCP PHASE1:Hg19::chr8:66750085..66750091,+#_1a317224837b1a65b5dc279c6c28d81dp@chr8:66750085..66750091, +
3.27e-147FFCP PHASE1:Hg19::chr9:136007795..136007801,-#_1a317224837b1a65b5dc279c6c28d81dp@chr9:136007795..136007801, -
3.27e-147FFCP PHASE1:Hg19::chr7:38357449..38357458,+#_1a317224837b1a65b5dc279c6c28d81dp@chr7:38357449..38357458, +
3.27e-147FFCP PHASE1:Hg19::chr11:65401401..65401406,+#_1a317224837b1a65b5dc279c6c28d81dp@chr11:65401401..65401406, +
3.27e-147FFCP PHASE1:Hg19::chr18:46360601..46360610,+#_1a317224837b1a65b5dc279c6c28d81dp@chr18:46360601..46360610, +
3.27e-147FFCP PHASE1:Hg19::chr19:45953439..45953444,+#_1a317224837b1a65b5dc279c6c28d81dp@chr19:45953439..45953444, +
3.27e-147FFCP PHASE1:Hg19::chr22:38597578..38597586,-#_1a317224837b1a65b5dc279c6c28d81d-, p@chr22:38597578..38597586
3.27e-147FFCP PHASE1:Hg19::chr2:145267967..145267972,-#_1a317224837b1a65b5dc279c6c28d81dp@chr2:145267967..145267972, -
3.27e-147FFCP PHASE1:Hg19::chr2:240467130..240467134,+#_1a317224837b1a65b5dc279c6c28d81dp@chr2:240467130..240467134, +
3.27e-147FFCP PHASE2:Hg19::chr2:145267967..145267972,-#_1a317224837b1a65b5dc279c6c28d81dp@chr2:145267967..145267972, -
3.27e-147FFCP PHASE2:Hg19::chr11:65401401..65401406,+#_1a317224837b1a65b5dc279c6c28d81dp@chr11:65401401..65401406, +
3.27e-147FFCP PHASE2:Hg19::chr18:46360601..46360610,+#_1a317224837b1a65b5dc279c6c28d81d+, p@chr18:46360601..46360610
3.27e-147FFCP PHASE2:Hg19::chr19:45953439..45953444,+#_1a317224837b1a65b5dc279c6c28d81d+, p@chr19:45953439..45953444
3.27e-147FFCP PHASE2:Hg19::chr7:38357449..38357458,+#_1a317224837b1a65b5dc279c6c28d81dp@chr7:38357449..38357458, +
8.93e-147FFCP PHASE2:Hg19::chr7:38320712..38320736,+#_4c1ca0598070f231b04b441724c1cf1dp@chr7:38320712..38320736, +
8.93e-147FFCP PHASE2:Hg19::chr1:167400749..167400756,-#_4c1ca0598070f231b04b441724c1cf1dp2@EF079882
8.93e-147FFCP PHASE2:Hg19::chr1:167420291..167420294,+#_4c1ca0598070f231b04b441724c1cf1dp@chr1:167420291..167420294, +
8.93e-147FFCP PHASE1:Hg19::chr7:38320712..38320736,+#_4c1ca0598070f231b04b441724c1cf1dp@chr7:38320712..38320736, +
8.93e-147FFCP PHASE1:Hg19::chr1:167400749..167400756,-#_4c1ca0598070f231b04b441724c1cf1dp2@EF079882
8.93e-147FFCP PHASE1:Hg19::chr1:167420291..167420294,+#_4c1ca0598070f231b04b441724c1cf1dp@chr1:167420291..167420294, +
8.98e-131FFCP PHASE1:Hg19::chr18:74804978..74804993,+#_22b494a5520b948f94bb6d6a8e37f288p@chr18:74804978..74804993, +
8.98e-131FFCP PHASE2:Hg19::chr22:38597593..38597598,-#_22b494a5520b948f94bb6d6a8e37f288p@chr22:38597593..38597598, -
8.98e-131FFCP PHASE1:Hg19::chr12:9994967..9994968,+#_22b494a5520b948f94bb6d6a8e37f288p@chr12:9994967..9994968, +
8.98e-131FFCP PHASE2:Hg19::chr5:172281403..172281405,-#_22b494a5520b948f94bb6d6a8e37f288p@chr5:172281403..172281405, -
8.98e-131FFCP PHASE2:Hg19::chr12:9994967..9994968,+#_22b494a5520b948f94bb6d6a8e37f288p@chr12:9994967..9994968, +
8.98e-131FFCP PHASE2:Hg19::chr18:74804978..74804993,+#_22b494a5520b948f94bb6d6a8e37f288p@chr18:74804978..74804993, +
8.98e-131FFCP PHASE2:Hg19::chr6:2940707..2940710,+#_22b494a5520b948f94bb6d6a8e37f288p@chr6:2940707..2940710, +
8.98e-131FFCP PHASE2:Hg19::chr6:37019056..37019063,-#_22b494a5520b948f94bb6d6a8e37f288p@chr6:37019056..37019063, -
8.98e-131FFCP PHASE1:Hg19::chr5:172281403..172281405,-#_22b494a5520b948f94bb6d6a8e37f288p@chr5:172281403..172281405, -
8.98e-131FFCP PHASE1:Hg19::chr6:2940707..2940710,+#_22b494a5520b948f94bb6d6a8e37f288p@chr6:2940707..2940710, +
8.98e-131FFCP PHASE1:Hg19::chr6:37019056..37019063,-#_22b494a5520b948f94bb6d6a8e37f288p@chr6:37019056..37019063, -
8.98e-131FFCP PHASE1:Hg19::chr22:38597593..38597598,-#_22b494a5520b948f94bb6d6a8e37f288p@chr22:38597593..38597598, -
2.33e-118FFCP PHASE1:Hg19::chr1:19275176..19275185,+#_5bff6ff16f029389f9e84a5e9cacacdf+, p@chr1:19275176..19275185
2.33e-118FFCP PHASE1:Hg19::chr22:23480066..23480080,-#_5bff6ff16f029389f9e84a5e9cacacdfp@chr22:23480066..23480080, -
2.33e-118FFCP PHASE1:Hg19::chr22:39474405..39474438,-#_5bff6ff16f029389f9e84a5e9cacacdf-, p@chr22:39474405..39474438
2.33e-118FFCP PHASE1:Hg19::chr2:111610415..111610439,+#_5bff6ff16f029389f9e84a5e9cacacdfp@chr2:111610415..111610439, +
2.33e-118FFCP PHASE1:Hg19::chr2:145263300..145263311,-#_5bff6ff16f029389f9e84a5e9cacacdfp@chr2:145263300..145263311, -
2.33e-118FFCP PHASE1:Hg19::chr7:50428238..50428247,+#_5bff6ff16f029389f9e84a5e9cacacdfp@chr7:50428238..50428247, +
2.33e-118FFCP PHASE1:Hg19::chr10:98431336..98431339,-#_5bff6ff16f029389f9e84a5e9cacacdfp@chr10:98431336..98431339, -
2.33e-118FFCP PHASE1:Hg19::chr11:121353266..121353274,-#_5bff6ff16f029389f9e84a5e9cacacdfp@chr11:121353266..121353274, -
2.33e-118FFCP PHASE1:Hg19::chr11:67037100..67037109,+#_5bff6ff16f029389f9e84a5e9cacacdfp@chr11:67037100..67037109, +
2.33e-118FFCP PHASE1:Hg19::chr12:129281246..129281271,+#_5bff6ff16f029389f9e84a5e9cacacdfp@chr12:129281246..129281271, +
2.33e-118FFCP PHASE1:Hg19::chr17:33776655..33776667,-#_5bff6ff16f029389f9e84a5e9cacacdfp@chr17:33776655..33776667, -
2.33e-118FFCP PHASE1:Hg19::chr17:34401981..34401994,+#_5bff6ff16f029389f9e84a5e9cacacdfp@chr17:34401981..34401994, +
2.33e-118FFCP PHASE1:Hg19::chr18:46341777..46341782,+#_5bff6ff16f029389f9e84a5e9cacacdfp@chr18:46341777..46341782, +
2.33e-118FFCP PHASE1:Hg19::chr19:41804394..41804429,+#_5bff6ff16f029389f9e84a5e9cacacdfp@chr19:41804394..41804429, +
2.33e-118FFCP PHASE1:Hg19::chr1:162518235..162518252,+#_5bff6ff16f029389f9e84a5e9cacacdfp@chr1:162518235..162518252, +
2.33e-118FFCP PHASE1:Hg19::chr1:167458837..167458845,-#_5bff6ff16f029389f9e84a5e9cacacdfp@chr1:167458837..167458845, -
2.33e-118FFCP PHASE2:Hg19::chr7:50428238..50428247,+#_5bff6ff16f029389f9e84a5e9cacacdfp@chr7:50428238..50428247, +
2.33e-118FFCP PHASE2:Hg19::chr1:162518235..162518252,+#_5bff6ff16f029389f9e84a5e9cacacdfp@chr1:162518235..162518252, +
2.33e-118FFCP PHASE2:Hg19::chr1:167458837..167458845,-#_5bff6ff16f029389f9e84a5e9cacacdf-, p@chr1:167458837..167458845
2.33e-118FFCP PHASE2:Hg19::chr1:19275176..19275185,+#_5bff6ff16f029389f9e84a5e9cacacdfp@chr1:19275176..19275185, +
2.33e-118FFCP PHASE2:Hg19::chr22:23480066..23480080,-#_5bff6ff16f029389f9e84a5e9cacacdfp@chr22:23480066..23480080, -
2.33e-118FFCP PHASE2:Hg19::chr22:39474405..39474438,-#_5bff6ff16f029389f9e84a5e9cacacdfp@chr22:39474405..39474438, -
2.33e-118FFCP PHASE2:Hg19::chr4:48116513..48116522,-#_5bff6ff16f029389f9e84a5e9cacacdfp9@TXK
2.33e-118FFCP PHASE2:Hg19::chr17:33776655..33776667,-#_5bff6ff16f029389f9e84a5e9cacacdfp@chr17:33776655..33776667, -
2.33e-118FFCP PHASE2:Hg19::chr17:34401981..34401994,+#_5bff6ff16f029389f9e84a5e9cacacdfp@chr17:34401981..34401994, +
2.33e-118FFCP PHASE2:Hg19::chr5:169705868..169705875,-#_5bff6ff16f029389f9e84a5e9cacacdfp@chr5:169705868..169705875, -
2.33e-118FFCP PHASE1:Hg19::chr4:48116513..48116522,-#_5bff6ff16f029389f9e84a5e9cacacdfp9@TXK
2.33e-118FFCP PHASE1:Hg19::chr5:169705868..169705875,-#_5bff6ff16f029389f9e84a5e9cacacdfp@chr5:169705868..169705875, -
2.33e-118FFCP PHASE2:Hg19::chr12:129281246..129281271,+#_5bff6ff16f029389f9e84a5e9cacacdfp@chr12:129281246..129281271, +
2.33e-118FFCP PHASE1:Hg19::chr7:38320586..38320596,+#_5bff6ff16f029389f9e84a5e9cacacdfp@chr7:38320586..38320596, +
2.33e-118FFCP PHASE2:Hg19::chr2:111610415..111610439,+#_5bff6ff16f029389f9e84a5e9cacacdfp@chr2:111610415..111610439, +
2.33e-118FFCP PHASE2:Hg19::chr2:145263300..145263311,-#_5bff6ff16f029389f9e84a5e9cacacdfp@chr2:145263300..145263311, -
2.33e-118FFCP PHASE2:Hg19::chr10:98431336..98431339,-#_5bff6ff16f029389f9e84a5e9cacacdfp@chr10:98431336..98431339, -
2.33e-118FFCP PHASE2:Hg19::chr11:121353266..121353274,-#_5bff6ff16f029389f9e84a5e9cacacdfp@chr11:121353266..121353274, -
2.33e-118FFCP PHASE2:Hg19::chr11:67037100..67037109,+#_5bff6ff16f029389f9e84a5e9cacacdfp@chr11:67037100..67037109, +
2.33e-118FFCP PHASE2:Hg19::chr18:46341777..46341782,+#_5bff6ff16f029389f9e84a5e9cacacdfp@chr18:46341777..46341782, +
2.33e-118FFCP PHASE2:Hg19::chr19:41804394..41804429,+#_5bff6ff16f029389f9e84a5e9cacacdfp@chr19:41804394..41804429, +
2.33e-118FFCP PHASE2:Hg19::chr7:38320586..38320596,+#_5bff6ff16f029389f9e84a5e9cacacdfp@chr7:38320586..38320596, +
3.48e-118FFCP PHASE2:Hg19::chr18:74804800..74804840,-#_e7137141ed38fcee58f4cafddfb4bc0dp@chr18:74804800..74804840, -
3.48e-118FFCP PHASE2:Hg19::chr19:10213257..10213267,+#_e7137141ed38fcee58f4cafddfb4bc0dp@chr19:10213257..10213267, +
3.48e-118FFCP PHASE2:Hg19::chr1:100494394..100494399,-#_e7137141ed38fcee58f4cafddfb4bc0dp@chr1:100494394..100494399, -
3.48e-118FFCP PHASE2:Hg19::chr1:172502793..172502831,-#_e7137141ed38fcee58f4cafddfb4bc0dp3@BC034700
3.48e-118FFCP PHASE1:Hg19::chr18:74804800..74804840,-#_e7137141ed38fcee58f4cafddfb4bc0dp@chr18:74804800..74804840, -
3.48e-118FFCP PHASE1:Hg19::chr19:10213257..10213267,+#_e7137141ed38fcee58f4cafddfb4bc0dp@chr19:10213257..10213267, +
3.48e-118FFCP PHASE1:Hg19::chr1:100494394..100494399,-#_e7137141ed38fcee58f4cafddfb4bc0dp@chr1:100494394..100494399, -
3.48e-118FFCP PHASE1:Hg19::chr1:172502793..172502831,-#_e7137141ed38fcee58f4cafddfb4bc0dp3@BC034700
5.2e-118FFCP PHASE2:Hg19::chr4:103421745..103421751,+#_e249bbf32d1f82790fe8fdd62d7db2f8p@chr4:103421745..103421751, +
5.2e-118FFCP PHASE1:Hg19::chr4:103421745..103421751,+#_e249bbf32d1f82790fe8fdd62d7db2f8p@chr4:103421745..103421751, +
7.78e-118FFCP PHASE1:Hg19::chr14:64108359..64108365,-#_3fd24065d3812ff4149c345c8732a3b3p9@WDR89
7.78e-118FFCP PHASE2:Hg19::chr14:64108359..64108365,-#_3fd24065d3812ff4149c345c8732a3b3p9@WDR89
7.78e-118FFCP PHASE2:Hg19::chr18:43268301..43268305,-#_3fd24065d3812ff4149c345c8732a3b3p@chr18:43268301..43268305, -
7.78e-118FFCP PHASE1:Hg19::chr18:43268301..43268305,-#_3fd24065d3812ff4149c345c8732a3b3p@chr18:43268301..43268305, -
4.06e-99FFCP PHASE1:Hg19::chr17:47465290..47465299,+#_daeeaf77e193fca6144e154223269365p@chr17:47465290..47465299, +
4.06e-99FFCP PHASE1:Hg19::chr17:66249672..66249675,+#_daeeaf77e193fca6144e154223269365p@chr17:66249672..66249675, +