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Coexpression cluster:C149

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Full id: C149_occipital_medial_brain_amygdala_parietal_cerebral_cerebellum



Phase1 CAGE Peaks

Hg19::chr11:109295305..109295312,+p13@C11orf87
Hg19::chr11:117708272..117708286,-p@chr11:117708272..117708286
-
Hg19::chr11:117711055..117711088,-p@chr11:117711055..117711088
-
Hg19::chr11:124616783..124616814,+p@chr11:124616783..124616814
+
Hg19::chr11:124616829..124616838,+p@chr11:124616829..124616838
+
Hg19::chr11:124616862..124616874,+p@chr11:124616862..124616874
+
Hg19::chr11:124616993..124617007,+p@chr11:124616993..124617007
+
Hg19::chr11:1579486..1579500,-p@chr11:1579486..1579500
-
Hg19::chr11:35276496..35276513,-p@chr11:35276496..35276513
-
Hg19::chr11:62475766..62475783,+p2@GNG3
Hg19::chr11:62476322..62476329,+p@chr11:62476322..62476329
+
Hg19::chr11:62476418..62476427,+p@chr11:62476418..62476427
+
Hg19::chr11:788371..788384,-p7@CEND1
Hg19::chr11:788579..788588,-p10@CEND1
Hg19::chr12:50264369..50264380,-p13@FAIM2
Hg19::chr12:50284493..50284508,-p@chr12:50284493..50284508
-
Hg19::chr12:50291815..50291826,-p@chr12:50291815..50291826
-
Hg19::chr12:57957251..57957258,+p@chr12:57957251..57957258
+
Hg19::chr12:57974899..57974914,+p12@KIF5A
Hg19::chr12:6804679..6804701,-p@chr12:6804679..6804701
-
Hg19::chr12:99145213..99145224,-p21@ANKS1B
Hg19::chr14:103986341..103986353,-p@chr14:103986341..103986353
-
Hg19::chr14:60063355..60063387,-p@chr14:60063355..60063387
-
Hg19::chr14:60063439..60063448,-p@chr14:60063439..60063448
-
Hg19::chr14:60063478..60063487,-p@chr14:60063478..60063487
-
Hg19::chr14:90873274..90873290,+p43@CALM1
Hg19::chr15:43813238..43813252,+p17@MAP1A
Hg19::chr15:43823079..43823119,+p@chr15:43823079..43823119
+
Hg19::chr15:90809459..90809470,+p16@NGRN
Hg19::chr16:19871596..19871607,-p@chr16:19871596..19871607
-
Hg19::chr16:56388775..56388786,+p@chr16:56388775..56388786
+
Hg19::chr16:743174..743190,-p@chr16:743174..743190
-
Hg19::chr16:743985..744004,-p@chr16:743985..744004
-
Hg19::chr16:747239..747260,-p13@FBXL16
Hg19::chr16:7568245..7568260,+p@chr16:7568245..7568260
+
Hg19::chr17:26369560..26369599,+p5@NLK
Hg19::chr17:7560287..7560299,+p13@ATP1B2
Hg19::chr17:77111716..77111739,-p1@AB528944
Hg19::chr18:3814105..3814117,-p@chr18:3814105..3814117
-
Hg19::chr19:18308079..18308090,-p@chr19:18308079..18308090
-
Hg19::chr19:18731255..18731287,+p@chr19:18731255..18731287
+
Hg19::chr19:36523273..36523285,-p13@CLIP3
Hg19::chr19:42474687..42474704,-p7@ATP1A3
Hg19::chr19:42485760..42485786,-p@chr19:42485760..42485786
-
Hg19::chr19:47112153..47112167,+p3@AK124456
Hg19::chr19:49933161..49933172,-p@chr19:49933161..49933172
-
Hg19::chr19:55684730..55684739,-p@chr19:55684730..55684739
-
Hg19::chr19:6494544..6494555,-p@chr19:6494544..6494555
-
Hg19::chr1:155851785..155851821,+p@chr1:155851785..155851821
+
Hg19::chr1:20810135..20810150,-p12@CAMK2N1
Hg19::chr1:240370881..240370888,+p@chr1:240370881..240370888
+
Hg19::chr1:26609014..26609025,-p@chr1:26609014..26609025
-
Hg19::chr1:41107481..41107490,-p5@RIMS3
Hg19::chr1:50661281..50661326,+p@chr1:50661281..50661326
+
Hg19::chr1:77987565..77987576,+p@chr1:77987565..77987576
+
Hg19::chr1:78024449..78024457,+p@chr1:78024449..78024457
+
Hg19::chr20:10256108..10256138,+p5@SNAP25
Hg19::chr20:10256139..10256151,+p6@SNAP25
Hg19::chr20:10258344..10258353,+p@chr20:10258344..10258353
+
Hg19::chr20:10277603..10277615,+p@chr20:10277603..10277615
+
Hg19::chr20:23356084..23356097,-p@chr20:23356084..23356097
-
Hg19::chr20:34820071..34820089,+p@chr20:34820071..34820089
+
Hg19::chr20:36572681..36572688,+p@chr20:36572681..36572688
+
Hg19::chr20:44038648..44038659,+p@chr20:44038648..44038659
+
Hg19::chr21:27394184..27394203,-p35@APP
Hg19::chr2:149679712..149679726,+p@chr2:149679712..149679726
+
Hg19::chr2:149679731..149679740,+p@chr2:149679731..149679740
+
Hg19::chr2:166246839..166246855,+p6@SCN2A
Hg19::chr2:17836942..17836979,+p@chr2:17836942..17836979
+
Hg19::chr2:210557572..210557587,+p@chr2:210557572..210557587
+
Hg19::chr2:241724426..241724440,-p@chr2:241724426..241724440
-
Hg19::chr2:26205144..26205178,-p8@KIF3C
Hg19::chr2:44546521..44546539,-p@chr2:44546521..44546539
-
Hg19::chr3:149684096..149684130,-p@chr3:149684096..149684130
-
Hg19::chr3:49662624..49662643,+p@chr3:49662624..49662643
+
Hg19::chr3:85008200..85008248,+p2@CADM2
Hg19::chr4:176556169..176556177,-p@chr4:176556169..176556177
-
Hg19::chr4:780193..780202,-p@chr4:780193..780202
-
Hg19::chr4:786348..786365,-p7@CPLX1
Hg19::chr5:149601723..149601751,-p@chr5:149601723..149601751
-
Hg19::chr5:149601763..149601781,-p@chr5:149601763..149601781
-
Hg19::chr5:149602244..149602265,-p@chr5:149602244..149602265
-
Hg19::chr5:149644556..149644576,-p@chr5:149644556..149644576
-
Hg19::chr5:175305938..175305959,+p@chr5:175305938..175305959
+
Hg19::chr5:175307176..175307188,+p@chr5:175307176..175307188
+
Hg19::chr5:176047349..176047358,-p@chr5:176047349..176047358
-
Hg19::chr5:176047426..176047433,-p@chr5:176047426..176047433
-
Hg19::chr5:176047734..176047748,-p@chr5:176047734..176047748
-
Hg19::chr6:17463258..17463269,+p@chr6:17463258..17463269
+
Hg19::chr6:31513145..31513194,-p@chr6:31513145..31513194
-
Hg19::chr6:31513206..31513220,-p@chr6:31513206..31513220
-
Hg19::chr6:31513929..31513944,-p@chr6:31513929..31513944
-
Hg19::chr6:46191004..46191017,-p@chr6:46191004..46191017
-
Hg19::chr6:5999372..5999383,-p@chr6:5999372..5999383
-
Hg19::chr6:96463946..96463957,+p4@FUT9
Hg19::chr7:104844144..104844161,-p7@SRPK2
Hg19::chr7:54617830..54617836,+p@chr7:54617830..54617836
+
Hg19::chr7:75959123..75959144,-p@chr7:75959123..75959144
-
Hg19::chr7:98445661..98445681,-p11@TMEM130
Hg19::chr7:98452904..98452938,-p@chr7:98452904..98452938
-
Hg19::chr7:98457898..98457907,-p@chr7:98457898..98457907
-
Hg19::chr7:98457936..98457953,-p@chr7:98457936..98457953
-
Hg19::chr8:107531209..107531222,+p@chr8:107531209..107531222
+
Hg19::chr8:24810399..24810424,-p@chr8:24810399..24810424
-
Hg19::chr8:24811752..24811777,-p@chr8:24811752..24811777
-
Hg19::chr9:130454420..130454442,+p@chr9:130454420..130454442
+
Hg19::chr9:137982097..137982113,+p@chr9:137982097..137982113
+
Hg19::chr9:138011822..138011833,+p17@OLFM1
Hg19::chr9:35748867..35748868,-p13@GBA2
Hg19::chr9:93375167..93375214,-p6@DIRAS2
Hg19::chr9:99220754..99220765,+p6@HABP4
Hg19::chrX:38525424..38525435,+p8@TSPAN7
Hg19::chrX:38547270..38547317,+p@chrX:38547270..38547317
+
Hg19::chrX:48689784..48689807,-p@chrX:48689784..48689807
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0006836neurotransmitter transport0.00897919041513745
GO:0031402sodium ion binding0.00897919041513745
GO:0005391sodium:potassium-exchanging ATPase activity0.00897919041513745
GO:0006887exocytosis0.00897919041513745
GO:0005871kinesin complex0.0173895998883744
GO:0044459plasma membrane part0.0184246069135385
GO:0006814sodium ion transport0.018569695369367
GO:0005875microtubule associated complex0.018569695369367
GO:0005886plasma membrane0.018569695369367
GO:0031420alkali metal ion binding0.0217426956653378
GO:0044425membrane part0.0217426956653378
GO:0016142O-glycoside catabolic process0.0217426956653378
GO:0033130acetylcholine receptor binding0.0217426956653378
GO:0016140O-glycoside metabolic process0.0217426956653378
GO:0045045secretory pathway0.0229413380745906
GO:0016020membrane0.0231312271272513
GO:0016192vesicle-mediated transport0.0266852479449219
GO:0007268synaptic transmission0.0266852479449219
GO:0051649establishment of cellular localization0.0266852479449219
GO:0016137glycoside metabolic process0.0266852479449219
GO:0016139glycoside catabolic process0.0266852479449219
GO:0035235ionotropic glutamate receptor signaling pathway0.0266852479449219
GO:0032940secretion by cell0.0266852479449219
GO:0005874microtubule0.0266852479449219
GO:0051641cellular localization0.026699697161869
GO:0005794Golgi apparatus0.0294353054527756
GO:0019226transmission of nerve impulse0.0294353054527756
GO:0005737cytoplasm0.0294353054527756
GO:0035253ciliary rootlet0.0294353054527756
GO:0016081synaptic vesicle docking during exocytosis0.0294353054527756
GO:0008422beta-glucosidase activity0.0294353054527756
GO:0006810transport0.0351884991944362
GO:0007243protein kinase cascade0.0374902103733455
GO:0046903secretion0.0380766997085923
GO:0051234establishment of localization0.0380766997085923
GO:0044464cell part0.0403543762700639
GO:0004348glucosylceramidase activity0.0410719101615185
GO:0030054cell junction0.0467409041374484
GO:0046920alpha(1,3)-fucosyltransferase activity0.0467409041374484
GO:0000287magnesium ion binding0.0476209460943883
GO:0044441cilium part0.0476209460943883
GO:0008542visual learning0.0476209460943883
GO:0003777microtubule motor activity0.0476209460943883
GO:0030955potassium ion binding0.0476209460943883
GO:0015662ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism0.0476209460943883
GO:0051179localization0.0476209460943883
GO:0016079synaptic vesicle exocytosis0.0476209460943883
GO:0001504neurotransmitter uptake0.0476209460943883
GO:0050796regulation of insulin secretion0.0476209460943883
GO:0006878cellular copper ion homeostasis0.0476209460943883
GO:0005890sodium:potassium-exchanging ATPase complex0.0476209460943883



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism2.09e-38115
central nervous system4.38e-3282
neural tube5.63e-3157
neural rod5.63e-3157
future spinal cord5.63e-3157
neural keel5.63e-3157
regional part of nervous system7.85e-3194
nervous system7.85e-3194
anterior neural tube1.70e-2542
regional part of forebrain1.81e-2541
forebrain1.81e-2541
future forebrain1.81e-2541
brain3.38e-2569
future brain3.38e-2569
regional part of brain1.29e-2459
neurectoderm1.01e-2190
gray matter1.84e-2134
brain grey matter1.84e-2134
telencephalon2.06e-2134
neural plate2.92e-2186
presumptive neural plate2.92e-2186
regional part of telencephalon8.56e-2133
cerebral hemisphere2.27e-2032
cerebral cortex3.51e-1625
pallium3.51e-1625
pre-chordal neural plate1.17e-1561
regional part of cerebral cortex1.30e-1522
ectoderm5.24e-15173
presumptive ectoderm5.24e-15173
ectoderm-derived structure1.82e-14169
neocortex2.39e-1420
anterior region of body4.81e-12129
craniocervical region4.81e-12129
head8.72e-12123
tube3.44e-11194
anatomical conduit4.59e-11241
multi-cellular organism4.97e-10659
epithelium4.31e-09309
anatomical cluster6.54e-09286
organism subdivision8.44e-09365
cell layer1.35e-08312
embryo1.38e-08612
embryonic structure3.29e-07605
developing anatomical structure3.29e-07605
germ layer3.91e-07604
embryonic tissue3.91e-07604
presumptive structure3.91e-07604
epiblast (generic)3.91e-07604
anatomical system4.89e-07625
anatomical group6.71e-07626
basal ganglion6.93e-079
nuclear complex of neuraxis6.93e-079
aggregate regional part of brain6.93e-079
collection of basal ganglia6.93e-079
cerebral subcortex6.93e-079
posterior neural tube7.88e-0715
chordal neural plate7.88e-0715
nucleus of brain9.78e-079
neural nucleus9.78e-079


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


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