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Coexpression cluster:C3240

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Full id: C3240_immature_CD14_Mast_Hair_Basophils_CD34_embryonic



Phase1 CAGE Peaks

  Short description
Hg19::chr12:111843149..111843189,- p@chr12:111843149..111843189
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Hg19::chr17:75319211..75319234,- p@chr17:75319211..75319234
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Hg19::chr3:5022272..5022321,+ p7@BHLHE40


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression clusterSummary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner

link to source dataset
data


No GOStat results

Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset

cell_data
uberon_data


Cell Type
Ontology termp-valuen
CD14-positive, CD16-negative classical monocyte1.99e-2242
classical monocyte4.12e-2045
myeloid leukocyte3.36e-1976
granulocyte monocyte progenitor cell1.31e-1771
myeloid lineage restricted progenitor cell1.74e-1770
mesenchymal cell9.07e-17358
connective tissue cell4.17e-16365
macrophage dendritic cell progenitor1.38e-1565
leukocyte5.09e-15140
motile cell7.84e-15390
monopoietic cell1.89e-1463
monocyte1.89e-1463
monoblast1.89e-1463
promonocyte1.89e-1463
somatic cell8.74e-14591
multi fate stem cell1.17e-13430
somatic stem cell5.39e-13436
myeloid cell5.83e-13112
common myeloid progenitor5.83e-13112
stem cell1.52e-12444
animal cell1.91e-11679
eukaryotic cell1.91e-11679
hematopoietic lineage restricted progenitor cell3.04e-11124
hematopoietic cell3.24e-11182
hematopoietic stem cell3.33e-10172
angioblastic mesenchymal cell3.33e-10172
nongranular leukocyte3.12e-09119
hematopoietic oligopotent progenitor cell3.76e-09165
hematopoietic multipotent progenitor cell3.76e-09165
native cell2.34e-08722
Uber Anatomy
Ontology termp-valuen
bone marrow3.66e-1680
connective tissue6.63e-16375
bone element1.06e-1586
skeletal element8.08e-14101
skeletal system8.08e-14101
lateral plate mesoderm1.72e-11216
hematopoietic system4.01e-11102
blood island4.01e-11102
immune system1.18e-09115
hemolymphoid system1.84e-09112
musculoskeletal system9.08e-09167


Overrepresented TFBS (DNA) motifs on this co-expression clusterSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysisSummary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner

link to source dataset

data


No analysis results for this cluster

Relative expression of the co-expression clusterSummary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.
Analyst:NA

link to data source
data


This analysis result is provided for C0 - C305 clusters.