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Coexpression cluster:C3840

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Full id: C3840_optic_cerebellum_Neutrophils_Eosinophils_occipital_skeletal_substantia



Phase1 CAGE Peaks

  Short description
Hg19::chr1:10270620..10270637,+ p1@KIF1B
Hg19::chr1:10270675..10270686,+ p5@KIF1B
Hg19::chr5:147763388..147763474,- p1@ENST00000501695
p1@uc003lpb.1


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression clusterSummary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner

link to source dataset
data


GO IDGO nameFDR corrected p-value
GO:0008089anterograde axon cargo transport0.00476863299187566
GO:0008088axon cargo transport0.00476863299187566
GO:0019894kinesin binding0.00476863299187566
GO:0007274neuromuscular synaptic transmission0.00476863299187566
GO:0007270nerve-nerve synaptic transmission0.00805369127516778
GO:0030659cytoplasmic vesicle membrane0.029936418226775
GO:0044433cytoplasmic vesicle part0.029936418226775
GO:0012506vesicle membrane0.029936418226775
GO:0003777microtubule motor activity0.0332038149063935
GO:0007018microtubule-based movement0.0346167432002826
GO:0005875microtubule associated complex0.0346167432002826
GO:0030705cytoskeleton-dependent intracellular transport0.0346167432002826
GO:0007268synaptic transmission0.0414458966207465
GO:0005874microtubule0.0414458966207465
GO:0007017microtubule-based process0.0414458966207465
GO:0019226transmission of nerve impulse0.0414458966207465
GO:0016023cytoplasmic membrane-bound vesicle0.0414458966207465
GO:0031988membrane-bound vesicle0.0414458966207465
GO:0031410cytoplasmic vesicle0.0457788767220064
GO:0031982vesicle0.0457788767220064



Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset

cell_data
uberon_data
disease_data


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


Overrepresented TFBS (DNA) motifs on this co-expression clusterSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysisSummary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner

link to source dataset

data


No analysis results for this cluster

Relative expression of the co-expression clusterSummary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.
Analyst:NA

link to data source
data


This analysis result is provided for C0 - C305 clusters.