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Coexpression cluster:C79

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Full id: C79_chorionic_Chondrocyte_Cardiac_Smooth_Fibroblast_Preadipocyte_Mesenchymal



Phase1 CAGE Peaks

Hg19::chr2:216225840..216225880,-p@chr2:216225840..216225880
-
Hg19::chr2:216226019..216226027,-p@chr2:216226019..216226027
-
Hg19::chr2:216226037..216226109,-p@chr2:216226037..216226109
-
Hg19::chr2:216226202..216226289,-p@chr2:216226202..216226289
-
Hg19::chr2:216226270..216226299,+p@chr2:216226270..216226299
+
Hg19::chr2:216226295..216226355,-p@chr2:216226295..216226355
-
Hg19::chr2:216226715..216226720,-p@chr2:216226715..216226720
-
Hg19::chr2:216226723..216226776,-p@chr2:216226723..216226776
-
Hg19::chr2:216226780..216226807,-p@chr2:216226780..216226807
-
Hg19::chr2:216229624..216229711,-p@chr2:216229624..216229711
-
Hg19::chr2:216230236..216230260,+p@chr2:216230236..216230260
+
Hg19::chr2:216230257..216230303,-p49@FN1
Hg19::chr2:216230308..216230359,-p50@FN1
Hg19::chr2:216232618..216232759,-p12@FN1
Hg19::chr2:216235008..216235020,-p70@FN1
Hg19::chr2:216235036..216235163,-p26@FN1
Hg19::chr2:216236330..216236334,-p@chr2:216236330..216236334
-
Hg19::chr2:216236659..216236746,-p38@FN1
Hg19::chr2:216236755..216236764,-p75@FN1
Hg19::chr2:216236789..216236803,-p64@FN1
Hg19::chr2:216236849..216236935,-p36@FN1
Hg19::chr2:216236941..216236998,-p45@FN1
Hg19::chr2:216236944..216236994,+p@chr2:216236944..216236994
+
Hg19::chr2:216236997..216237046,+p@chr2:216236997..216237046
+
Hg19::chr2:216237000..216237103,-p28@FN1
Hg19::chr2:216237128..216237139,-p79@FN1
Hg19::chr2:216237349..216237362,-p67@FN1
Hg19::chr2:216238037..216238075,+p@chr2:216238037..216238075
+
Hg19::chr2:216238068..216238142,-p31@FN1
Hg19::chr2:216239959..216240125,-p4@FN1
Hg19::chr2:216240035..216240051,+p@chr2:216240035..216240051
+
Hg19::chr2:216240376..216240402,+p@chr2:216240376..216240402
+
Hg19::chr2:216240380..216240381,-p82@FN1
Hg19::chr2:216240386..216240458,-p23@FN1
Hg19::chr2:216241210..216241264,+p@chr2:216241210..216241264
+
Hg19::chr2:216241247..216241253,-p71@FN1
Hg19::chr2:216241256..216241335,-p10@FN1
Hg19::chr2:216241304..216241361,+p@chr2:216241304..216241361
+
Hg19::chr2:216241339..216241404,-p7@FN1
Hg19::chr2:216242889..216242900,+p@chr2:216242889..216242900
+
Hg19::chr2:216242906..216242955,+p@chr2:216242906..216242955
+
Hg19::chr2:216242925..216242993,-p27@FN1
Hg19::chr2:216243869..216243940,+p@chr2:216243869..216243940
+
Hg19::chr2:216243872..216244063,-p@chr2:216243872..216244063
-
Hg19::chr2:216243953..216243994,+p@chr2:216243953..216243994
+
Hg19::chr2:216244346..216244358,-p@chr2:216244346..216244358
-
Hg19::chr2:216244391..216244398,-p@chr2:216244391..216244398
-
Hg19::chr2:216245562..216245577,-p58@FN1
Hg19::chr2:216245579..216245596,-p57@FN1
Hg19::chr2:216245602..216245652,-p33@FN1
Hg19::chr2:216245657..216245732,-p18@FN1
Hg19::chr2:216245737..216245751,-p65@FN1
Hg19::chr2:216245756..216245767,-p62@FN1
Hg19::chr2:216245779..216245803,-p52@FN1
Hg19::chr2:216246957..216246989,+p@chr2:216246957..216246989
+
Hg19::chr2:216246960..216247057,-p13@FN1
Hg19::chr2:216247013..216247028,+p@chr2:216247013..216247028
+
Hg19::chr2:216248054..216248100,+p@chr2:216248054..216248100
+
Hg19::chr2:216248075..216248078,-p76@FN1
Hg19::chr2:216248091..216248096,-p72@FN1
Hg19::chr2:216248100..216248102,-p80@FN1
Hg19::chr2:216248106..216248212,-p11@FN1
Hg19::chr2:216248785..216248799,-p32@FN1
Hg19::chr2:216248805..216248814,-p40@FN1
Hg19::chr2:216248820..216248848,-p15@FN1
Hg19::chr2:216248830..216248863,+p@chr2:216248830..216248863
+
Hg19::chr2:216248853..216248891,-p2@FN1
Hg19::chr2:216248896..216248910,-p24@FN1
Hg19::chr2:216249575..216249598,+p@chr2:216249575..216249598
+
Hg19::chr2:216249608..216249613,-p68@FN1
Hg19::chr2:216249615..216249696,-p14@FN1
Hg19::chr2:216251434..216251483,+p@chr2:216251434..216251483
+
Hg19::chr2:216251438..216251451,-p@chr2:216251438..216251451
-
Hg19::chr2:216251453..216251544,-p@chr2:216251453..216251544
-
Hg19::chr2:216251489..216251515,+p@chr2:216251489..216251515
+
Hg19::chr2:216251537..216251550,+p@chr2:216251537..216251550
+
Hg19::chr2:216251545..216251580,-p@chr2:216251545..216251580
-
Hg19::chr2:216251581..216251601,-p@chr2:216251581..216251601
-
Hg19::chr2:216251602..216251632,-p@chr2:216251602..216251632
-
Hg19::chr2:216251633..216251692,-p@chr2:216251633..216251692
-
Hg19::chr2:216252936..216252952,+p@chr2:216252936..216252952
+
Hg19::chr2:216252958..216252995,+p@chr2:216252958..216252995
+
Hg19::chr2:216252959..216253014,-p@chr2:216252959..216253014
-
Hg19::chr2:216253021..216253036,-p@chr2:216253021..216253036
-
Hg19::chr2:216256353..216256364,+p@chr2:216256353..216256364
+
Hg19::chr2:216256377..216256419,-p@chr2:216256377..216256419
-
Hg19::chr2:216256378..216256407,+p@chr2:216256378..216256407
+
Hg19::chr2:216256414..216256432,+p@chr2:216256414..216256432
+
Hg19::chr2:216256427..216256438,-p@chr2:216256427..216256438
-
Hg19::chr2:216256433..216256470,+p@chr2:216256433..216256470
+
Hg19::chr2:216256439..216256547,-p5@FN1
Hg19::chr2:216256489..216256512,+p@chr2:216256489..216256512
+
Hg19::chr2:216256725..216256736,-p74@FN1
Hg19::chr2:216257754..216257766,-p69@FN1
Hg19::chr2:216257770..216257790,-p60@FN1
Hg19::chr2:216259188..216259201,-p@chr2:216259188..216259201
-
Hg19::chr2:216259270..216259317,+p@chr2:216259270..216259317
+
Hg19::chr2:216259278..216259288,-p51@FN1
Hg19::chr2:216259298..216259308,-p55@FN1
Hg19::chr2:216259313..216259329,-p46@FN1
Hg19::chr2:216259325..216259350,+p@chr2:216259325..216259350
+
Hg19::chr2:216259334..216259354,-p41@FN1
Hg19::chr2:216259354..216259419,+p@chr2:216259354..216259419
+
Hg19::chr2:216259356..216259399,-p17@FN1
Hg19::chr2:216259404..216259444,-p21@FN1
Hg19::chr2:216259445..216259455,-p53@FN1
Hg19::chr2:216261849..216261862,+p@chr2:216261849..216261862
+
Hg19::chr2:216261870..216261879,+p@chr2:216261870..216261879
+
Hg19::chr2:216261885..216261914,+p@chr2:216261885..216261914
+
Hg19::chr2:216261906..216261920,-p@chr2:216261906..216261920
-
Hg19::chr2:216262426..216262440,-p56@FN1
Hg19::chr2:216262447..216262454,-p66@FN1
Hg19::chr2:216262464..216262489,-p25@FN1
Hg19::chr2:216262492..216262555,-p6@FN1
Hg19::chr2:216262556..216262578,-p20@FN1
Hg19::chr2:216264013..216264051,+p@chr2:216264013..216264051
+
Hg19::chr2:216264027..216264048,-p34@FN1
Hg19::chr2:216264051..216264090,-p3@FN1
Hg19::chr2:216269109..216269248,-p@chr2:216269109..216269248
-
Hg19::chr2:216269135..216269225,+p@chr2:216269135..216269225
+
Hg19::chr2:216269250..216269274,-p@chr2:216269250..216269274
-
Hg19::chr2:216269265..216269289,+p@chr2:216269265..216269289
+
Hg19::chr2:216269285..216269305,-p@chr2:216269285..216269305
-
Hg19::chr2:216269309..216269333,-p@chr2:216269309..216269333
-
Hg19::chr2:216269322..216269342,+p@chr2:216269322..216269342
+
Hg19::chr2:216269340..216269352,-p@chr2:216269340..216269352
-
Hg19::chr2:216269367..216269374,-p@chr2:216269367..216269374
-
Hg19::chr2:216269379..216269384,-p@chr2:216269379..216269384
-
Hg19::chr2:216270982..216270997,+p@chr2:216270982..216270997
+
Hg19::chr2:216270984..216271000,-p@chr2:216270984..216271000
-
Hg19::chr2:216271005..216271137,-p@chr2:216271005..216271137
-
Hg19::chr2:216271094..216271145,+p@chr2:216271094..216271145
+
Hg19::chr2:216271143..216271154,-p@chr2:216271143..216271154
-
Hg19::chr2:216271146..216271196,+p@chr2:216271146..216271196
+
Hg19::chr2:216271160..216271176,-p@chr2:216271160..216271176
-
Hg19::chr2:216271178..216271208,-p@chr2:216271178..216271208
-
Hg19::chr2:216271223..216271235,-p@chr2:216271223..216271235
-
Hg19::chr2:216271841..216271920,+p@chr2:216271841..216271920
+
Hg19::chr2:216271872..216271915,-p@chr2:216271872..216271915
-
Hg19::chr2:216271920..216271987,-p@chr2:216271920..216271987
-
Hg19::chr2:216271921..216271932,+p@chr2:216271921..216271932
+
Hg19::chr2:216271985..216272019,+p@chr2:216271985..216272019
+
Hg19::chr2:216271991..216272051,-p@chr2:216271991..216272051
-
Hg19::chr2:216272837..216272858,+p@chr2:216272837..216272858
+
Hg19::chr2:216272850..216272854,-p@chr2:216272850..216272854
-
Hg19::chr2:216272860..216272923,-p@chr2:216272860..216272923
-
Hg19::chr2:216273040..216273062,+p@chr2:216273040..216273062
+
Hg19::chr2:216273041..216273156,-p@chr2:216273041..216273156
-
Hg19::chr2:216274317..216274350,-p43@FN1
Hg19::chr2:216274354..216274463,-p8@FN1
Hg19::chr2:216274423..216274443,+p@chr2:216274423..216274443
+
Hg19::chr2:216274641..216274703,+p@chr2:216274641..216274703
+
Hg19::chr2:216274684..216274712,-p37@FN1
Hg19::chr2:216274715..216274759,-p22@FN1
Hg19::chr2:216274738..216274750,+p@chr2:216274738..216274750
+
Hg19::chr2:216274762..216274777,-p48@FN1
Hg19::chr2:216274784..216274843,-p16@FN1
Hg19::chr2:216274786..216274797,+p@chr2:216274786..216274797
+
Hg19::chr2:216274803..216274815,+p@chr2:216274803..216274815
+
Hg19::chr2:216279555..216279566,+p@chr2:216279555..216279566
+
Hg19::chr2:216279570..216279641,+p@chr2:216279570..216279641
+
Hg19::chr2:216279600..216279620,-p@chr2:216279600..216279620
-
Hg19::chr2:216279623..216279686,-p@chr2:216279623..216279686
-
Hg19::chr2:216279653..216279654,+p@chr2:216279653..216279654
+
Hg19::chr2:216283958..216283993,+p@chr2:216283958..216283993
+
Hg19::chr2:216283990..216284004,-p@chr2:216283990..216284004
-
Hg19::chr2:216284007..216284022,+p@chr2:216284007..216284022
+
Hg19::chr2:216284024..216284054,+p@chr2:216284024..216284054
+
Hg19::chr2:216284048..216284059,-p@chr2:216284048..216284059
-
Hg19::chr2:216284075..216284086,-p@chr2:216284075..216284086
-
Hg19::chr2:216285392..216285435,+p@chr2:216285392..216285435
+
Hg19::chr2:216285416..216285421,-p@chr2:216285416..216285421
-
Hg19::chr2:216285430..216285470,-p@chr2:216285430..216285470
-
Hg19::chr2:216285441..216285489,+p@chr2:216285441..216285489
+
Hg19::chr2:216285472..216285532,-p30@FN1
Hg19::chr2:216285491..216285502,+p@chr2:216285491..216285502
+
Hg19::chr2:216286809..216286870,+p@chr2:216286809..216286870
+
Hg19::chr2:216286835..216286854,-p@chr2:216286835..216286854
-
Hg19::chr2:216286866..216286877,-p@chr2:216286866..216286877
-
Hg19::chr2:216286896..216286907,+p@chr2:216286896..216286907
+
Hg19::chr2:216286896..216286912,-p@chr2:216286896..216286912
-
Hg19::chr2:216286919..216286942,+p@chr2:216286919..216286942
+
Hg19::chr2:216286925..216286942,-p@chr2:216286925..216286942
-
Hg19::chr2:216286951..216286963,-p@chr2:216286951..216286963
-
Hg19::chr2:216288084..216288131,+p@chr2:216288084..216288131
+
Hg19::chr2:216288096..216288100,-p@chr2:216288096..216288100
-
Hg19::chr2:216288105..216288140,-p@chr2:216288105..216288140
-
Hg19::chr2:216288133..216288158,+p@chr2:216288133..216288158
+
Hg19::chr2:216288145..216288156,-p@chr2:216288145..216288156
-
Hg19::chr2:216288165..216288235,-p@chr2:216288165..216288235
-
Hg19::chr2:216288167..216288200,+p@chr2:216288167..216288200
+
Hg19::chr2:216288213..216288229,+p@chr2:216288213..216288229
+
Hg19::chr2:216288238..216288248,-p@chr2:216288238..216288248
-
Hg19::chr2:216288862..216288879,+p@chr2:216288862..216288879
+
Hg19::chr2:216288881..216288922,+p@chr2:216288881..216288922
+
Hg19::chr2:216288893..216288957,-p@chr2:216288893..216288957
-
Hg19::chr2:216288924..216288958,+p@chr2:216288924..216288958
+
Hg19::chr2:216288963..216288992,+p@chr2:216288963..216288992
+
Hg19::chr2:216288963..216289017,-p@chr2:216288963..216289017
-
Hg19::chr2:216289001..216289015,+p@chr2:216289001..216289015
+
Hg19::chr2:216289020..216289031,-p@chr2:216289020..216289031
-
Hg19::chr2:216289040..216289056,-p@chr2:216289040..216289056
-
Hg19::chr2:216289824..216289844,+p@chr2:216289824..216289844
+
Hg19::chr2:216289849..216289895,+p@chr2:216289849..216289895
+
Hg19::chr2:216289851..216289877,-p42@FN1
Hg19::chr2:216289880..216289901,-p44@FN1
Hg19::chr2:216289907..216289919,-p47@FN1
Hg19::chr2:216289922..216290014,-p9@FN1
Hg19::chr2:216289931..216289975,+p@chr2:216289931..216289975
+
Hg19::chr2:216292922..216293012,-p@chr2:216292922..216293012
-
Hg19::chr2:216292925..216292962,+p@chr2:216292925..216292962
+
Hg19::chr2:216292976..216293025,+p@chr2:216292976..216293025
+
Hg19::chr2:216293013..216293070,-p@chr2:216293013..216293070
-
Hg19::chr2:216293031..216293041,+p@chr2:216293031..216293041
+
Hg19::chr2:216295443..216295487,+p@chr2:216295443..216295487
+
Hg19::chr2:216295480..216295498,-p@chr2:216295480..216295498
-
Hg19::chr2:216295498..216295542,+p@chr2:216295498..216295542
+
Hg19::chr2:216295510..216295544,-p@chr2:216295510..216295544
-
Hg19::chr2:216295550..216295567,-p@chr2:216295550..216295567
-
Hg19::chr2:216296541..216296600,+p@chr2:216296541..216296600
+
Hg19::chr2:216296603..216296619,+p@chr2:216296603..216296619
+
Hg19::chr2:216296612..216296623,-p@chr2:216296612..216296623
-
Hg19::chr2:216296625..216296645,+p@chr2:216296625..216296645
+
Hg19::chr2:216296635..216296642,-p@chr2:216296635..216296642
-
Hg19::chr2:216296649..216296678,-p@chr2:216296649..216296678
-
Hg19::chr2:216298040..216298094,+p@chr2:216298040..216298094
+
Hg19::chr2:216298063..216298110,-p29@FN1
Hg19::chr2:216298108..216298152,+p@chr2:216298108..216298152
+
Hg19::chr2:216298113..216298192,-p19@FN1
Hg19::chr2:216299432..216299457,+p@chr2:216299432..216299457
+
Hg19::chr2:216299437..216299441,-p@chr2:216299437..216299441
-
Hg19::chr2:216299443..216299554,-p@chr2:216299443..216299554
-
Hg19::chr2:216299463..216299527,+p@chr2:216299463..216299527
+
Hg19::chr2:216300364..216300450,+p@chr2:216300364..216300450
+
Hg19::chr2:216300557..216300586,+p2@ENST00000412951
Hg19::chr2:216300597..216300650,+p1@ENST00000412951
Hg19::chr2:216300784..216300798,-p1@FN1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0005518collagen binding0.0141227416041969
GO:0006953acute-phase response0.0141227416041969
GO:0005793ER-Golgi intermediate compartment0.0141227416041969
GO:0008201heparin binding0.0141227416041969
GO:0002526acute inflammatory response0.0141227416041969
GO:0005539glycosaminoglycan binding0.0141227416041969
GO:0030247polysaccharide binding0.0141227416041969
GO:0005201extracellular matrix structural constituent0.0141227416041969
GO:0001871pattern binding0.0141227416041969
GO:0007169transmembrane receptor protein tyrosine kinase signaling pathway0.0210173083716001
GO:0016477cell migration0.0211992764094495
GO:0006954inflammatory response0.0230959432654946
GO:0007167enzyme linked receptor protein signaling pathway0.0230959432654946
GO:0051674localization of cell0.0249028611797951
GO:0006928cell motility0.0249028611797951
GO:0005578proteinaceous extracellular matrix0.0249028611797951
GO:0009611response to wounding0.0249028611797951
GO:0030246carbohydrate binding0.0265774428614414
GO:0006952defense response0.0307621756616904
GO:0009605response to external stimulus0.0316760861886259
GO:0044421extracellular region part0.0417735321671555
GO:0022610biological adhesion0.0417735321671555
GO:0007155cell adhesion0.0417735321671555



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
somite4.18e-1871
presomitic mesoderm4.18e-1871
presumptive segmental plate4.18e-1871
dermomyotome4.18e-1871
trunk paraxial mesoderm4.18e-1871
dense mesenchyme tissue4.44e-1873
epithelial vesicle6.54e-1878
paraxial mesoderm1.60e-1772
presumptive paraxial mesoderm1.60e-1772
trunk mesenchyme8.34e-17122
multilaminar epithelium3.18e-1683
mesenchyme2.37e-15160
entire embryonic mesenchyme2.37e-15160
skeletal muscle tissue7.73e-1562
striated muscle tissue7.73e-1562
myotome7.73e-1562
muscle tissue2.00e-1464
musculature2.00e-1464
musculature of body2.00e-1464
unilaminar epithelium8.90e-14148
splanchnic layer of lateral plate mesoderm6.09e-1383
epithelial tube1.67e-11117
vasculature3.81e-1178
vascular system3.81e-1178
mesoderm1.19e-10315
mesoderm-derived structure1.19e-10315
presumptive mesoderm1.19e-10315
cardiovascular system1.57e-10109
integument1.75e-1046
integumental system1.75e-1046
circulatory system2.48e-10112
artery6.28e-1042
arterial blood vessel6.28e-1042
arterial system6.28e-1042
surface structure1.52e-0999
organ component layer1.93e-0966
trunk1.00e-08199
skin of body1.10e-0841
vessel1.69e-0868
connective tissue3.46e-08371
epithelial tube open at both ends6.68e-0859
blood vessel6.68e-0859
blood vasculature6.68e-0859
vascular cord6.68e-0859
extraembryonic structure7.60e-0824
heart1.43e-0724
primitive heart tube1.43e-0724
primary heart field1.43e-0724
anterior lateral plate mesoderm1.43e-0724
heart tube1.43e-0724
heart primordium1.43e-0724
cardiac mesoderm1.43e-0724
cardiogenic plate1.43e-0724
heart rudiment1.43e-0724
systemic artery1.74e-0733
systemic arterial system1.74e-0733
adipose tissue2.03e-0714
organism subdivision2.20e-07264
extraembryonic membrane2.76e-0714
membranous layer2.76e-0714
primary circulatory organ6.13e-0727


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
FOXA1#3169331.542982496749870.008488753747321770.0324105049578321
POLR2A#54301981.794074805732063.76660584990767e-321.65285944688448e-29



Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data