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{{Coexpression_clusters
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348369,0.46359,0.236531,0.712999,0.68716,0.191625,0.116269,0.0470551,0.274046,0.805814,0.396189,0.233338,0.314616,0.537051,0.641011,0.39419,1.25378,0.281506,0.935963,0.722879,0.165252,0.352585,0.20845,0.0313677,0.20579,0.404426,0.547451,0.395523,0.207288,0.340749,1.26659,0.235234,0.235672,0.301189,0.47544,0.365597,0.518466,0.675323,0.550604,0.486559,0.214602,0.797754,0.947672,0.466348,0.244111,0.435652,0.281305,0.434711,0.762758,0.477672,0.848838,0.660336,0.494624,0.627106,1.0348,1.4,0.712787,1.2388,0.328852,1.40734,0.0579262,0.945703,0.104203,0.0955465,0.610619,0.644006,0.709631,0.832314,1.24887,0.659298,0.49429,0.439665,0.89511,0.0102458,0.175904,0.272913,0.575506,1.4989,1.12715,0.868602,0.739223,0.509773,0.238337,1.62266,0.743843,0.780743,0.579925,0.0696508,0.187593,0.733724,0.775299,0.690713,0.616014,0.37138,0.675372,0.460348,0.31439,0.22412,0.283874,0.772599,0.741574,0.384185,1.07963,0.204477,0.171258,0.354459,0.624851,0.515375,0.937551,0.57318,0.400807,0.504966,1.18924,0.644741,0.468435,0.744085,2.24435,0.182384,0.869279,0.358161,0.993705,0.50181,1.13991,0.0752959,0.9239,0.394712,1.09788,1.95265,1.55112,1.06096,0.470062,0.777301,0.617705,0.42776,0.601672,1.79367,1.60827,0.168379,0.193209,0.0287097,0.869654,1.33157,0.477214,1.26919,0.560015,1.19853,0.314669,0.28899,1.05976,0.851493,0.708865,0.793294,0.633206,0.493542,0.158769,0.473159,0.393553|tfbs_overrepresentation_jaspar=MA0003.1;0.0250581,MA0004.1;0.380329,MA0006.1;0.236135,MA0007.1;0.363007,MA0009.1;0.828613,MA0014.1;0.0036779,MA0017.1;0.270554,MA0019.1;0.520264,MA0024.1;0.725404,MA0025.1;0.960689,MA0027.1;2.43535,MA0028.1;0.25013,MA0029.1;0.744375,MA0030.1;0.733118,MA0031.1;0.669876,MA0038.1;0.477043,MA0040.1;0.750125,MA0041.1;0.397617,MA0042.1;0.367902,MA0043.1;0.828925,MA0046.1;0.817858,MA0048.1;0.0613414,MA0050.1;0.368721,MA0051.1;0.473017,MA0052.1;0.753928,MA0055.1;0.344701,MA0056.1;0,MA0057.1;0.211138,MA0058.1;0.293055,MA0059.1;0.291897,MA0060.1;0.138988,MA0061.1;1.80643,MA0063.1;0,MA0066.1;0.477449,MA0067.1;1.1435,MA0068.1;2.13887,MA0069.1;0.814052,MA0070.1;0.803003,MA0071.1;0.440254,MA0072.1;0.798564,MA0073.1;0.0824235,MA0074.1;0.4723,MA0076.1;0.307383,MA0077.1;0.790956,MA0078.1;0.568317,MA0081.1;0.292043,MA0083.1;0.836033,MA0084.1;1.32998,MA0087.1;0.79615,MA0088.1;1.25978,MA0089.1;0,MA0090.1;0.320494,MA0091.1;0.382762,MA0092.1;0.347826,MA0093.1;0.238771,MA0095.1;0,MA0098.1;0,MA0100.1;0.49029,MA0101.1;1.95071,MA0103.1;1.20737,MA0105.1;2.70068,MA0106.1;0.516528,MA0107.1;1.60878,MA0108.2;0.666881,MA0109.1;0,MA0111.1;0.33284,MA0113.1;0.532314,MA0114.1;0.174997,MA0115.1;1.06753,MA0116.1;0.182037,MA0117.1;0.865782,MA0119.1;0.277531,MA0122.1;0.891407,MA0124.1;1.0263,MA0125.1;0.942948,MA0130.1;0,MA0131.1;0.585907,MA0132.1;0,MA0133.1;0,MA0135.1;0.858623,MA0136.1;0.483775,MA0139.1;0.109245,MA0140.1;0.437738,MA0141.1;0.290336,MA0142.1;0.638837,MA0143.1;0.532484,MA0144.1;0.951129,MA0145.1;0.14293,MA0146.1;0.606611,MA0147.1;0.184931,MA0148.1;0.403564,MA0149.1;0.428597,MA0062.2;0.114378,MA0035.2;0.437071,MA0039.2;0.0109452,MA0138.2;0.569505,MA0002.2;0.407187,MA0137.2;0.255808,MA0104.2;0.138396,MA0047.2;0.504873,MA0112.2;0.0329985,MA0065.2;0.0371828,MA0150.1;0.315136,MA0151.1;0,MA0152.1;0.443956,MA0153.1;0.926242,MA0154.1;0.185581,MA0155.1;0.296882,MA0156.1;0.257809,MA0157.1;0.612166,MA0158.1;0,MA0159.1;1.64451,MA0160.1;0.417847,MA0161.1;0,MA0162.1;0.108522,MA0163.1;0.299639,MA0164.1;0.544294,MA0080.2;0.238846,MA0018.2;1.28752,MA0099.2;0.444294,MA0079.2;0.000284498,MA0102.2;1.36707,MA0258.1;0.155735,MA0259.1;0.191914,MA0442.1;0}}
|full_id=C810_b_cord_xeroderma_adult_plasma_splenic_hairy
 
|id=C810
 
|ontology_enrichment_celltype=CL:0000738!4.70e-30!140;CL:0002087!6.32e-27!119;CL:0000542!1.44e-26!53;CL:0000051!1.44e-26!53;CL:0002031!2.65e-26!124;CL:0000838!8.64e-26!52;CL:0000037!3.95e-20!172;CL:0000566!3.95e-20!172;CL:0002032!1.53e-19!165;CL:0000837!1.53e-19!165;CL:0000988!1.80e-19!182;CL:0000945!6.66e-19!24;CL:0000826!6.66e-19!24;CL:0000236!6.41e-11!14;CL:0000084!7.01e-08!25;CL:0000827!7.01e-08!25
 
|ontology_enrichment_disease=DOID:0060058!3.51e-07!10
 
|ontology_enrichment_uberon=UBERON:0002390!1.61e-13!102;UBERON:0003061!1.61e-13!102;UBERON:0002193!7.10e-13!112;UBERON:0000178!5.26e-08!15;UBERON:0000179!5.26e-08!15;UBERON:0000463!5.26e-08!15
 
}}
 

Latest revision as of 02:31, 17 September 2013


Full id: C810_b_cord_xeroderma_adult_plasma_splenic_hairy



Phase1 CAGE Peaks

  Short description
Hg19::chr12:104319130..104319137,+ p@chr12:104319130..104319137
+
Hg19::chr14:75982215..75982255,+ p@chr14:75982215..75982255
+
Hg19::chr19:36204309..36204335,+ p1@ZBTB32
Hg19::chr19:6592539..6592560,- -
p@chr19:6592539..6592560
Hg19::chr6:149353782..149353788,- p5@ENST00000433442
Hg19::chr6:149353827..149353847,- p2@ENST00000433442
Hg19::chr6:149353899..149353911,- p4@ENST00000433442
Hg19::chr6:149373615..149373627,+ p@chr6:149373615..149373627
+
Hg19::chr9:137283392..137283414,+ p@chr9:137283392..137283414
+
Hg19::chr9:137284044..137284078,+ p@chr9:137284044..137284078
+


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression clusterSummary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner

link to source dataset
data


No GOStat results

Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset

cell_data
uberon_data
disease_data


Disease
Ontology termp-valuen
lymphoma6.80e-3310
hematologic cancer1.44e-0951
immune system cancer1.44e-0951
genetic disease2.02e-081
monogenic disease2.02e-081
xeroderma pigmentosum2.02e-081
non-Hodgkin lymphoma2.17e-081
cutaneous T cell lymphoma2.17e-081
mycosis fungoides2.17e-081
anemia2.50e-081
acute leukemia3.57e-081


Overrepresented TFBS (DNA) motifs on this co-expression clusterSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.0250581
MA0004.10.380329
MA0006.10.236135
MA0007.10.363007
MA0009.10.828613
MA0014.10.0036779
MA0017.10.270554
MA0019.10.520264
MA0024.10.725404
MA0025.10.960689
MA0027.12.43535
MA0028.10.25013
MA0029.10.744375
MA0030.10.733118
MA0031.10.669876
MA0038.10.477043
MA0040.10.750125
MA0041.10.397617
MA0042.10.367902
MA0043.10.828925
MA0046.10.817858
MA0048.10.0613414
MA0050.10.368721
MA0051.10.473017
MA0052.10.753928
MA0055.10.344701
MA0056.10
MA0057.10.211138
MA0058.10.293055
MA0059.10.291897
MA0060.10.138988
MA0061.11.80643
MA0063.10
MA0066.10.477449
MA0067.11.1435
MA0068.12.13887
MA0069.10.814052
MA0070.10.803003
MA0071.10.440254
MA0072.10.798564
MA0073.10.0824235
MA0074.10.4723
MA0076.10.307383
MA0077.10.790956
MA0078.10.568317
MA0081.10.292043
MA0083.10.836033
MA0084.11.32998
MA0087.10.79615
MA0088.11.25978
MA0089.10
MA0090.10.320494
MA0091.10.382762
MA0092.10.347826
MA0093.10.238771
MA0095.10
MA0098.10
MA0100.10.49029
MA0101.11.95071
MA0103.11.20737
MA0105.12.70068
MA0106.10.516528
MA0107.11.60878
MA0108.20.666881
MA0109.10
MA0111.10.33284
MA0113.10.532314
MA0114.10.174997
MA0115.11.06753
MA0116.10.182037
MA0117.10.865782
MA0119.10.277531
MA0122.10.891407
MA0124.11.0263
MA0125.10.942948
MA0130.10
MA0131.10.585907
MA0132.10
MA0133.10
MA0135.10.858623
MA0136.10.483775
MA0139.10.109245
MA0140.10.437738
MA0141.10.290336
MA0142.10.638837
MA0143.10.532484
MA0144.10.951129
MA0145.10.14293
MA0146.10.606611
MA0147.10.184931
MA0148.10.403564
MA0149.10.428597
MA0062.20.114378
MA0035.20.437071
MA0039.20.0109452
MA0138.20.569505
MA0002.20.407187
MA0137.20.255808
MA0104.20.138396
MA0047.20.504873
MA0112.20.0329985
MA0065.20.0371828
MA0150.10.315136
MA0151.10
MA0152.10.443956
MA0153.10.926242
MA0154.10.185581
MA0155.10.296882
MA0156.10.257809
MA0157.10.612166
MA0158.10
MA0159.11.64451
MA0160.10.417847
MA0161.10
MA0162.10.108522
MA0163.10.299639
MA0164.10.544294
MA0080.20.238846
MA0018.21.28752
MA0099.20.444294
MA0079.20.000284498
MA0102.21.36707
MA0258.10.155735
MA0259.10.191914
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysisSummary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner

link to source dataset

data


(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
BATF#10538819.48624143384293.35986009675805e-103.37080142790887e-08
BCL11A#53335925.53250959324648.09175691577641e-131.15292633086872e-10
BCL3#602517.27355140186924.52539555281746e-060.00014146297100889
EBF1#187965.34388010794140.0002809265931316460.00298957534747055
EGR1#195862.992907456886080.006446587185075730.0280111132893212
IRF4#3662715.34015888072094.36532178232436e-082.86555525848003e-06
MAFF#23764316.89460694698350.0006113627942544190.00507552614222077
MAFK#797538.130219941348970.004957565697075180.0231630297426222
MEF2A#4205916.86890781867963.32312367299441e-113.82228759123197e-09
MEF2C#4208520.6556772463121.88780031393599e-066.9520443225374e-05
NFKB1#479094.939257081774451.84959706943667e-066.85729742047911e-05
PAX5#507985.335652424942268.62942979482416e-060.000234212322853857
POLR2A#5430102.147453176558070.0004793377491637920.00436494508544052
POU2F2#545276.374286840419771.70647444265859e-050.000390924510455846
SP1#666773.988866964698630.0003734365591501510.00371158553493363
SRF#672245.518871304867120.004058059466626480.0194127735725084
TAF1#687272.34013240002170.01040839844348330.0386366705185338
TBP#690882.965416549677110.0007302875668644710.00581684740663198
TCF12#693877.44412543153056.0261004481986e-060.000179407042391509



Relative expression of the co-expression clusterSummary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.
Analyst:NA

link to data source
data


This analysis result is provided for C0 - C305 clusters.