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DOID:2531

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Name:hematologic cancer
Namespace:FANTOM
Definition:"An immune system cancer located_in the hematological system that is characterized by uncontrolled cellular proliferation in blood, bone marrow and lymph nodes." [url:http://en.wikipedia.org/wiki/Blood_cancer, url:http://www.cancer.gov/dictionary/?CdrID
Xrefs:
links:

MSH:D019337
NCI:C27134
SNOMEDCT_2010_1_31:414388001
SNOMEDCT_2010_1_31:414644002

UMLS_CUI:C0376544
Synonyms: "blood cancer" EXACT [CSP2005:2004-0139]
"Hematologic malignancy" EXACT [SNOMEDCT_2005_07_31:269475001]
"Hematologic malignancy (disorder)" EXACT [SNOMEDCT_2005_07_31:127221002]
"Hematologic neoplasm (disorder)" EXACT [SNOMEDCT_2005_07_31:129154003]
"Hematological tumors" EXACT [NCI2004_11_17:C27134]
"hematopoietic and lymphoid system tumor" EXACT []
"hematopoietic cancer" EXACT []
"hematopoietic neoplasm (morphologic abnormality)" EXACT [SNOMEDCT_2005_07_31:414388001]
"hematopoietic tumors" EXACT [NCI2004_11_17:C27134]
"malignant hematopoietic neoplasm (morphologic abnormality)" EXACT [SNOMEDCT_2005_07_31:414644002]
Alt_id: DOID:1034
DOID:2532

Ontology association
Each term has an is_a parent in the Disease Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to DISEASE ontologies.

link to ontology dataset
data


Parents

is_a:DOID:0060083(immune system cancer)



Children


is a:DOID:0060058 (lymphoma),DOID:1240 (leukemia),DOID:4960 (bone marrow cancer)


Ontology Tree: Loaded from BioPortal

FF samples

Human (Homo sapiens)

  • 10399-106A3 (acute myeloid leukemia (FAB M5) cell line:THP-1 (fresh))
  • 10400-106A4 (acute myeloid leukemia (FAB M5) cell line:THP-1 (revived))
  • 10405-106A9 (acute myeloid leukemia (FAB M5) cell line:THP-1 (thawed))
  • 10409-106B4 (chronic myelogenous leukemia cell line:KU812)
  • 10416-106C2 (chronic lymphocytic leukemia (T-CLL) cell line:SKW-3)
  • 10421-106C7 (adult T-cell leukemia cell line:ATN-1)
  • 10422-106C8 (Burkitt's lymphoma cell line:DAUDI)
  • 10424-106D1 (splenic lymphoma with villous lymphocytes cell line:SLVL)
  • 10429-106D6 (acute lymphoblastic leukemia (T-ALL) cell line:HPB-ALL)
  • 10435-106E3 (Hodgkin's lymphoma cell line:HD-Mar2)

... further results Mouse (Mus musculus)

  • 10399-106A3 (acute myeloid leukemia (FAB M5) cell line:THP-1 (fresh))
  • 10400-106A4 (acute myeloid leukemia (FAB M5) cell line:THP-1 (revived))
  • 10405-106A9 (acute myeloid leukemia (FAB M5) cell line:THP-1 (thawed))
  • 10409-106B4 (chronic myelogenous leukemia cell line:KU812)
  • 10416-106C2 (chronic lymphocytic leukemia (T-CLL) cell line:SKW-3)
  • 10421-106C7 (adult T-cell leukemia cell line:ATN-1)
  • 10422-106C8 (Burkitt's lymphoma cell line:DAUDI)
  • 10424-106D1 (splenic lymphoma with villous lymphocytes cell line:SLVL)
  • 10429-106D6 (acute lymphoblastic leukemia (T-ALL) cell line:HPB-ALL)
  • 10435-106E3 (Hodgkin's lymphoma cell line:HD-Mar2)

... further results

Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with DOID:2531 (hematologic cancer), sorted by p-values
Analyst: Hideya Kawaji

link to source dataset
human : data
mouse : data


P-valueFFCPShort description
7.91e-91FFCP PHASE2:Hg19::chr6:135513595..135513617,+#_a20eb265833d1e6cc9022a91dc375fc6p4@MYB
7.91e-91FFCP PHASE1:Hg19::chr6:135513595..135513617,+#_a20eb265833d1e6cc9022a91dc375fc6p4@MYB
1.58e-86FFCP PHASE1:Mm9::chr10:76688454..76688462,+#_32c0398a2d5eea688b99633ad877d6fap@chr10:76688454..76688462, +
1.58e-86FFCP PHASE2:Mm9::chr11:102331415..102331424,-#_32c0398a2d5eea688b99633ad877d6fap9@Itga2b
1.58e-86FFCP PHASE1:Mm9::chr10:76688464..76688474,+#_32c0398a2d5eea688b99633ad877d6fap@chr10:76688464..76688474, +
1.58e-86FFCP PHASE1:Mm9::chr11:102331415..102331424,-#_32c0398a2d5eea688b99633ad877d6fap9@Itga2b
1.58e-86FFCP PHASE2:Mm9::chr10:76688454..76688462,+#_32c0398a2d5eea688b99633ad877d6fap@chr10:76688454..76688462, +
1.58e-86FFCP PHASE2:Mm9::chr10:76688464..76688474,+#_32c0398a2d5eea688b99633ad877d6fap@chr10:76688464..76688474, +
3.61e-86FFCP PHASE2:Hg19::chr12:58329793..58329806,-#_38b14e5ff00ce6017583d44d6a49e81ep2@ENST00000547492
3.61e-86FFCP PHASE1:Hg19::chr12:58329793..58329806,-#_38b14e5ff00ce6017583d44d6a49e81ep2@ENST00000547492
1.2e-85FFCP PHASE2:Hg19::chr12:58329776..58329791,-#_f218044066aa1b4044348e9e878e50d3p3@ENST00000547492
1.2e-85FFCP PHASE1:Hg19::chr12:58329776..58329791,-#_f218044066aa1b4044348e9e878e50d3p3@ENST00000547492
4.4e-85FFCP PHASE2:Hg19::chr6:135533394..135533403,+#_56353b6a30b232628212414a487bca05p@chr6:135533394..135533403, +
4.4e-85FFCP PHASE1:Hg19::chr6:135533394..135533403,+#_56353b6a30b232628212414a487bca05p@chr6:135533394..135533403, +
2.22e-77FFCP PHASE2:Hg19::chr6:135502472..135502489,+#_571b16c6de62d105bc30cfd931653e94p3@MYB
2.22e-77FFCP PHASE1:Hg19::chr6:135502472..135502489,+#_571b16c6de62d105bc30cfd931653e94p3@MYB
9.4e-76FFCP PHASE2:Hg19::chr6:68598272..68598298,-#_1c20b7e1e044bf18182d7d7cbe5b1b69p@chr6:68598272..68598298, -
9.4e-76FFCP PHASE1:Hg19::chr6:68598272..68598298,-#_1c20b7e1e044bf18182d7d7cbe5b1b69p@chr6:68598272..68598298, -
2.03e-75FFCP PHASE1:Hg19::chr16:29674970..29675007,+#_071eab6eb6b5b23c25ed8cdd46c1f0d2p4@SPN
2.03e-75FFCP PHASE2:Hg19::chr16:29674970..29675007,+#_071eab6eb6b5b23c25ed8cdd46c1f0d2p4@SPN
7.69e-75FFCP PHASE2:Hg19::chr12:58329762..58329773,-#_db0c148d1c4b9f19a85e60f2021a87adp5@ENST00000547492
7.69e-75FFCP PHASE1:Hg19::chr12:58329762..58329773,-#_db0c148d1c4b9f19a85e60f2021a87adp5@ENST00000547492
1.51e-73FFCP PHASE2:Hg19::chr1:202129105..202129140,-#_cc3d9a859d7f5c9041f4240c599a1dd8p2@PTPN7
1.51e-73FFCP PHASE1:Hg19::chr1:202129105..202129140,-#_cc3d9a859d7f5c9041f4240c599a1dd8p2@PTPN7
1.25e-71FFCP PHASE1:Hg19::chr6:68592986..68593000,-#_a282651b8f9239b01fffc30b8adc6674p@chr6:68592986..68593000, -
1.25e-71FFCP PHASE2:Hg19::chr6:68592986..68593000,-#_a282651b8f9239b01fffc30b8adc6674p@chr6:68592986..68593000, -
1.49e-71FFCP PHASE2:Hg19::chr6:68598314..68598325,-#_23d335eb9923a0dec315c31d67aaa239p@chr6:68598314..68598325, -
1.49e-71FFCP PHASE1:Hg19::chr6:68598314..68598325,-#_23d335eb9923a0dec315c31d67aaa239p@chr6:68598314..68598325, -
7.94e-68FFCP PHASE1:Hg19::chr6:68593536..68593560,-#_56d155c7f85e0ef73d39dec803e7e845p@chr6:68593536..68593560, -
7.94e-68FFCP PHASE1:Hg19::chr6:68596384..68596400,-#_56d155c7f85e0ef73d39dec803e7e845p@chr6:68596384..68596400, -
7.94e-68FFCP PHASE2:Hg19::chr6:68593536..68593560,-#_56d155c7f85e0ef73d39dec803e7e845p@chr6:68593536..68593560, -
7.94e-68FFCP PHASE2:Hg19::chr6:68596384..68596400,-#_56d155c7f85e0ef73d39dec803e7e845p@chr6:68596384..68596400, -
7.94e-68FFCP PHASE1:Hg19::chr6:68591611..68591627,-#_56d155c7f85e0ef73d39dec803e7e845p@chr6:68591611..68591627, -
7.94e-68FFCP PHASE2:Hg19::chr6:68591611..68591627,-#_56d155c7f85e0ef73d39dec803e7e845p@chr6:68591611..68591627, -
3.59e-67FFCP PHASE2:Hg19::chr16:29675010..29675041,+#_153785aaa3545f8fa39fe9637628409ep5@SPN
3.59e-67FFCP PHASE1:Hg19::chr16:29675010..29675041,+#_153785aaa3545f8fa39fe9637628409ep5@SPN
1.24e-65FFCP PHASE2:Hg19::chr6:135516978..135516993,+#_de3cbb14e2bb319f3dac3ed3556a7862p7@MYB
1.24e-65FFCP PHASE1:Hg19::chr6:135516978..135516993,+#_de3cbb14e2bb319f3dac3ed3556a7862p7@MYB
1.33e-65FFCP PHASE1:Mm9::chrX:160480258..160480272,-#_fee63bdc12ab2100f254cee5375e40cdp@chrX:160480258..160480272, -
1.33e-65FFCP PHASE2:Mm9::chr19:8798483..8798487,+#_fee63bdc12ab2100f254cee5375e40cdp1@ENSMUST00000082787
1.33e-65FFCP PHASE1:Mm9::chr2:156853485..156853494,-#_fee63bdc12ab2100f254cee5375e40cdp13@9830001H06Rik
1.33e-65FFCP PHASE2:Mm9::chrX:160480258..160480272,-#_fee63bdc12ab2100f254cee5375e40cdp@chrX:160480258..160480272, -
1.33e-65FFCP PHASE2:Mm9::chr2:156853485..156853494,-#_fee63bdc12ab2100f254cee5375e40cdp13@9830001H06Rik
1.33e-65FFCP PHASE1:Mm9::chr19:8798483..8798487,+#_fee63bdc12ab2100f254cee5375e40cdp1@ENSMUST00000082787
1.56e-64FFCP PHASE1:Hg19::chr6:68598245..68598268,-#_c24d5dc18edd1a1582d07cad66ffc958p@chr6:68598245..68598268, -
1.56e-64FFCP PHASE2:Hg19::chr6:68598245..68598268,-#_c24d5dc18edd1a1582d07cad66ffc958p@chr6:68598245..68598268, -
3.76e-64FFCP PHASE1:Hg19::chr6:68598507..68598519,-#_bb905090403d5bf872bb0fb28ea3eecep@chr6:68598507..68598519, -
3.76e-64FFCP PHASE2:Hg19::chr6:68598507..68598519,-#_bb905090403d5bf872bb0fb28ea3eecep@chr6:68598507..68598519, -
4.16e-64FFCP PHASE1:Hg19::chr6:68598587..68598598,-#_fb2ad0a96ba2594fe0e224b9197e9d11p@chr6:68598587..68598598, -
4.16e-64FFCP PHASE1:Hg19::chr6:68595369..68595417,-#_fb2ad0a96ba2594fe0e224b9197e9d11p@chr6:68595369..68595417, -
4.16e-64FFCP PHASE2:Hg19::chr6:68595369..68595417,-#_fb2ad0a96ba2594fe0e224b9197e9d11p@chr6:68595369..68595417, -
4.16e-64FFCP PHASE2:Hg19::chr6:68598587..68598598,-#_fb2ad0a96ba2594fe0e224b9197e9d11p@chr6:68598587..68598598, -
2.54e-62FFCP PHASE1:Hg19::chr11:17297848..17297868,+#_203606c2f0ddd23c1582a1762009e2f5p9@NUCB2
2.54e-62FFCP PHASE2:Hg19::chr11:17297848..17297868,+#_203606c2f0ddd23c1582a1762009e2f5p9@NUCB2
1.55e-60FFCP PHASE2:Hg19::chr6:135526382..135526388,+#_036d20cc396ac332cc7bb1d0c6c6a4b6p@chr6:135526382..135526388, +
1.55e-60FFCP PHASE1:Hg19::chr6:135526382..135526388,+#_036d20cc396ac332cc7bb1d0c6c6a4b6p@chr6:135526382..135526388, +
2.15e-60FFCP PHASE2:Hg19::chr6:68598534..68598555,-#_aafe90a944e339f71f5103241b4c22cbp@chr6:68598534..68598555, -
2.15e-60FFCP PHASE1:Hg19::chr6:68596826..68596859,-#_aafe90a944e339f71f5103241b4c22cbp@chr6:68596826..68596859, -
2.15e-60FFCP PHASE1:Hg19::chr6:68592948..68592958,-#_aafe90a944e339f71f5103241b4c22cbp@chr6:68592948..68592958, -
2.15e-60FFCP PHASE2:Hg19::chr6:68592948..68592958,-#_aafe90a944e339f71f5103241b4c22cbp@chr6:68592948..68592958, -
2.15e-60FFCP PHASE1:Hg19::chr6:68597599..68597612,-#_aafe90a944e339f71f5103241b4c22cbp@chr6:68597599..68597612, -
2.15e-60FFCP PHASE2:Hg19::chr6:68596826..68596859,-#_aafe90a944e339f71f5103241b4c22cbp@chr6:68596826..68596859, -
2.15e-60FFCP PHASE1:Hg19::chr6:68596698..68596715,-#_aafe90a944e339f71f5103241b4c22cbp@chr6:68596698..68596715, -
2.15e-60FFCP PHASE2:Hg19::chr6:68596698..68596715,-#_aafe90a944e339f71f5103241b4c22cbp@chr6:68596698..68596715, -
2.15e-60FFCP PHASE1:Hg19::chr6:68598534..68598555,-#_aafe90a944e339f71f5103241b4c22cbp@chr6:68598534..68598555, -
2.15e-60FFCP PHASE2:Hg19::chr6:68597599..68597612,-#_aafe90a944e339f71f5103241b4c22cbp@chr6:68597599..68597612, -
2.4e-60FFCP PHASE1:Hg19::chr19:695494..695510,-#_188392a4d9e355bf221f43a4f759f009p3@PRSS57
2.4e-60FFCP PHASE2:Hg19::chr19:695494..695510,-#_188392a4d9e355bf221f43a4f759f009p3@PRSS57
5.98e-60FFCP PHASE2:Hg19::chr6:68599042..68599067,-#_7c0ae6a1d9ff45b7059dbee72c19ba09p1@uc003pes.1, p1@uc003pet.1
5.98e-60FFCP PHASE1:Hg19::chr6:68599042..68599067,-#_7c0ae6a1d9ff45b7059dbee72c19ba09p1@uc003pes.1, p1@uc003pet.1
1.21e-59FFCP PHASE1:Hg19::chr11:33913475..33913549,-#_99b606b685c616b429973e3d35510aa0p5@LMO2
1.21e-59FFCP PHASE2:Hg19::chr11:33913475..33913549,-#_99b606b685c616b429973e3d35510aa0p5@LMO2
1.58e-59FFCP PHASE2:Hg19::chr6:135501708..135501716,+#_b8123b60492bcc97e43edbc77361535dp@chr6:135501708..135501716, +
1.58e-59FFCP PHASE1:Hg19::chr6:135501708..135501716,+#_b8123b60492bcc97e43edbc77361535dp@chr6:135501708..135501716, +
1.6e-59FFCP PHASE2:Hg19::chrX:65146038..65146063,-#_0af9d4bed3f3740cb864e7e512e2630cp@chrX:65146038..65146063, -
1.6e-59FFCP PHASE1:Hg19::chrX:65146038..65146063,-#_0af9d4bed3f3740cb864e7e512e2630cp@chrX:65146038..65146063, -
2.35e-59FFCP PHASE2:Hg19::chr8:130560794..130560810,-#_b3cb338bb44c16b3fe5e4f0597215a4fp@chr8:130560794..130560810, -
2.35e-59FFCP PHASE1:Hg19::chr8:130560794..130560810,-#_b3cb338bb44c16b3fe5e4f0597215a4fp@chr8:130560794..130560810, -
2.1e-58FFCP PHASE1:Hg19::chr8:130560752..130560768,-#_7d3ecd07304adca936492b4038ae4c38p@chr8:130560752..130560768, -
2.1e-58FFCP PHASE2:Hg19::chr8:130560752..130560768,-#_7d3ecd07304adca936492b4038ae4c38p@chr8:130560752..130560768, -
3.28e-58FFCP PHASE2:Mm9::chr11:104171122..104171127,+#_8a8d0c934e883278e89abfeeb8aed2dfp@chr11:104171122..104171127, +
3.28e-58FFCP PHASE1:Mm9::chr11:104171122..104171127,+#_8a8d0c934e883278e89abfeeb8aed2dfp@chr11:104171122..104171127, +
9.68e-58FFCP PHASE1:Hg19::chr6:68598984..68598997,-#_5898f8b18fa99e8434d573803c425453p2@uc003pes.1, p2@uc003pet.1
9.68e-58FFCP PHASE2:Hg19::chr6:68598984..68598997,-#_5898f8b18fa99e8434d573803c425453p2@uc003pes.1, p2@uc003pet.1
9.63e-57FFCP PHASE2:Hg19::chr6:68593520..68593534,-#_6c18fdc2a4f16a466c67006d34e33254p@chr6:68593520..68593534, -
9.63e-57FFCP PHASE1:Hg19::chr6:68593520..68593534,-#_6c18fdc2a4f16a466c67006d34e33254p@chr6:68593520..68593534, -
1.09e-56FFCP PHASE1:Hg19::chr6:68596783..68596797,-#_7e5f1d8628ac340812353dd6506a8204p@chr6:68596783..68596797, -
1.09e-56FFCP PHASE2:Hg19::chr6:68596343..68596355,-#_7e5f1d8628ac340812353dd6506a8204p@chr6:68596343..68596355, -
1.09e-56FFCP PHASE2:Hg19::chr6:68596783..68596797,-#_7e5f1d8628ac340812353dd6506a8204-, p@chr6:68596783..68596797
1.09e-56FFCP PHASE1:Hg19::chr6:68596343..68596355,-#_7e5f1d8628ac340812353dd6506a8204p@chr6:68596343..68596355, -
4.1e-55FFCP PHASE1:Hg19::chr6:68593206..68593218,-#_a2aeff6d2fb0e8eb9e207b3e53b12d8ap@chr6:68593206..68593218, -
4.1e-55FFCP PHASE2:Hg19::chr6:68593206..68593218,-#_a2aeff6d2fb0e8eb9e207b3e53b12d8ap@chr6:68593206..68593218, -
1.62e-54FFCP PHASE2:Hg19::chr12:58329689..58329704,-#_0d13799af4f6aef077f5afe06f36ad5fp4@ENST00000547492
1.62e-54FFCP PHASE1:Hg19::chr12:58329689..58329704,-#_0d13799af4f6aef077f5afe06f36ad5fp4@ENST00000547492
2.35e-54FFCP PHASE2:Hg19::chr3:53231298..53231310,+#_2c3e2cfe5f2b489325141f108844c723p@chr3:53231298..53231310, +
2.35e-54FFCP PHASE1:Hg19::chr3:53231298..53231310,+#_2c3e2cfe5f2b489325141f108844c723p@chr3:53231298..53231310, +
3.68e-54FFCP PHASE2:Hg19::chr3:18020982..18021001,+#_ae9b3d6638504ee2a258f3e63d0114abp@chr3:18020982..18021001, +
3.68e-54FFCP PHASE1:Hg19::chr3:18020982..18021001,+#_ae9b3d6638504ee2a258f3e63d0114abp@chr3:18020982..18021001, +
1.18e-53FFCP PHASE1:Hg19::chr11:17297872..17297908,+#_82879a884ca84ad0d3381d27452ff722p7@NUCB2
1.18e-53FFCP PHASE2:Hg19::chr11:17297872..17297908,+#_82879a884ca84ad0d3381d27452ff722p7@NUCB2