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{{Novel_motif
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Latest revision as of 06:12, 9 September 2013

name:motif124_AATNCANCACT

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0034332 adherens junction organization 4.676747e-15
GO:0050896 response to stimulus 8.128399e-15
GO:0048583 regulation of response to stimulus 1.587519e-13
GO:0070584 mitochondrion morphogenesis 3.253570e-13
GO:0006955 immune response 5.038678e-13
GO:0023052 signaling 5.292504e-13
GO:0002376 immune system process 6.718726e-13
GO:0007165 signal transduction 6.756497e-13
GO:0007154 cell communication 7.040683e-13
GO:0051716 cellular response to stimulus 2.768604e-12
GO:0065008 regulation of biological quality 1.652654e-11
GO:0070972 protein localization in endoplasmic reticulum 3.910387e-11
GO:0045216 cell-cell junction organization 4.273008e-11
GO:0007166 cell surface receptor linked signaling pathway 5.157190e-11
GO:0032501 multicellular organismal process 2.442033e-10
GO:0034329 cell junction assembly 2.747252e-10
GO:0006626 protein targeting to mitochondrion 1.149764e-9
GO:0071636 positive regulation of transforming growth factor beta production 1.573204e-9
GO:0033036 macromolecule localization 1.786731e-9
GO:0034330 cell junction organization 2.189839e-9
GO:0007186 G-protein coupled receptor protein signaling pathway 3.327249e-9
GO:0007275 multicellular organismal development 3.732867e-9
GO:0006621 protein retention in ER lumen 6.870480e-9
GO:0070585 protein localization in mitochondrion 7.552075e-9
GO:0008104 protein localization 7.776208e-9
GO:0072655 establishment of protein localization in mitochondrion 7.887131e-9
GO:0048513 organ development 8.278199e-9
GO:0048518 positive regulation of biological process 9.035453e-9
GO:0021572 rhombomere 6 development 1.142648e-8
GO:0032502 developmental process 1.260300e-8
GO:0051336 regulation of hydrolase activity 1.464655e-8
GO:0045321 leukocyte activation 1.761741e-8
GO:0001798 positive regulation of type IIa hypersensitivity 2.017845e-8
GO:0006952 defense response 2.242763e-8
GO:0042403 thyroid hormone metabolic process 2.741257e-8
GO:0070050 neuron homeostasis 3.163111e-8
GO:0006612 protein targeting to membrane 3.296047e-8
GO:0002706 regulation of lymphocyte mediated immunity 3.716477e-8
GO:0033365 protein localization to organelle 4.461418e-8
GO:0042110 T cell activation 4.758896e-8
GO:0009913 epidermal cell differentiation 6.269384e-8
GO:0071634 regulation of transforming growth factor beta production 6.346441e-8
GO:0048856 anatomical structure development 6.618919e-8
GO:0001819 positive regulation of cytokine production 7.094939e-8
GO:0045040 protein import into mitochondrial outer membrane 7.383440e-8
GO:0042445 hormone metabolic process 7.557807e-8
GO:0045766 positive regulation of angiogenesis 7.926618e-8
GO:0035621 ER to Golgi ceramide transport 7.982914e-8
GO:0032101 regulation of response to external stimulus 1.020525e-7
GO:0051270 regulation of cellular component movement 1.057842e-7
GO:0048731 system development 1.059735e-7
GO:0001952 regulation of cell-matrix adhesion 1.066097e-7
GO:0002682 regulation of immune system process 1.197280e-7
GO:0008588 release of cytoplasmic sequestered NF-kappaB 1.264918e-7
GO:0072594 establishment of protein localization to organelle 1.279991e-7
GO:0042221 response to chemical stimulus 1.564899e-7
GO:0048630 skeletal muscle tissue growth 1.626688e-7
GO:0042592 homeostatic process 1.839806e-7
GO:0045765 regulation of angiogenesis 1.894823e-7
GO:0006605 protein targeting 2.113010e-7
GO:0002885 positive regulation of hypersensitivity 2.635099e-7
GO:0030216 keratinocyte differentiation 3.369833e-7
GO:0051179 localization 3.480711e-7
GO:0050776 regulation of immune response 3.523247e-7
GO:0040012 regulation of locomotion 3.681285e-7
GO:0007005 mitochondrion organization 3.862986e-7
GO:0010817 regulation of hormone levels 3.867747e-7
GO:0006590 thyroid hormone generation 3.966899e-7
GO:0031641 regulation of myelination 4.038871e-7
GO:0048522 positive regulation of cellular process 4.126423e-7
GO:2000145 regulation of cell motility 4.287227e-7
GO:0001970 positive regulation of activation of membrane attack complex 4.374365e-7
GO:0023051 regulation of signaling 4.475781e-7
GO:0046716 muscle cell homeostasis 4.481278e-7
GO:0045056 transcytosis 4.493270e-7
GO:2000146 negative regulation of cell motility 5.186238e-7
GO:0030336 negative regulation of cell migration 5.327142e-7
GO:0002703 regulation of leukocyte mediated immunity 5.888134e-7
GO:0051271 negative regulation of cellular component movement 6.322929e-7
GO:0090072 positive regulation of sodium ion transport via voltage-gated sodium channel activity 6.351379e-7
GO:0070613 regulation of protein processing 7.637720e-7
GO:0050766 positive regulation of phagocytosis 8.282006e-7
GO:0050793 regulation of developmental process 8.770449e-7
GO:0032879 regulation of localization 9.258649e-7
GO:0030334 regulation of cell migration 9.497591e-7
GO:0042993 positive regulation of transcription factor import into nucleus 1.028797e-6
GO:0009268 response to pH 1.132971e-6
GO:0007267 cell-cell signaling 1.159776e-6
GO:0051893 regulation of focal adhesion assembly 1.162106e-6
GO:0022407 regulation of cell-cell adhesion 1.278853e-6
GO:0030878 thyroid gland development 1.330169e-6
GO:0034619 cellular chaperone-mediated protein complex assembly 1.363757e-6
GO:0002709 regulation of T cell mediated immunity 1.419663e-6
GO:0046649 lymphocyte activation 1.487542e-6
GO:0010575 positive regulation vascular endothelial growth factor production 1.514649e-6
GO:0002883 regulation of hypersensitivity 1.558982e-6
GO:0051056 regulation of small GTPase mediated signal transduction 1.685351e-6
GO:0051131 chaperone-mediated protein complex assembly 1.803495e-6
GO:0032908 regulation of transforming growth factor beta1 production 1.880773e-6
GO:0048468 cell development 1.936457e-6
GO:0001654 eye development 1.960261e-6
GO:0072376 protein activation cascade 1.989450e-6
GO:0046578 regulation of Ras protein signal transduction 1.995367e-6
GO:0050789 regulation of biological process 2.074484e-6
GO:0040013 negative regulation of locomotion 2.089983e-6
GO:0015031 protein transport 2.321496e-6
GO:0048584 positive regulation of response to stimulus 2.703209e-6
GO:0032318 regulation of Ras GTPase activity 2.720702e-6
GO:0032914 positive regulation of transforming growth factor beta1 production 3.302736e-6
GO:0042178 xenobiotic catabolic process 3.544265e-6
GO:0048869 cellular developmental process 3.589194e-6
GO:0010954 positive regulation of protein processing 3.669333e-6
GO:0006184 GTP catabolic process 3.788947e-6
GO:0070727 cellular macromolecule localization 3.790913e-6
GO:0042098 T cell proliferation 3.797002e-6
GO:0034613 cellular protein localization 3.965754e-6
GO:0007156 homophilic cell adhesion 4.078180e-6
GO:0045834 positive regulation of lipid metabolic process 4.417627e-6
GO:0007423 sensory organ development 4.597697e-6
GO:0017038 protein import 4.882954e-6
GO:0030449 regulation of complement activation 5.076239e-6
GO:0048732 gland development 5.281701e-6
GO:0006958 complement activation, classical pathway 5.414634e-6
GO:0042462 eye photoreceptor cell development 5.996158e-6
GO:0050877 neurological system process 6.276163e-6
GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus 6.364837e-6
GO:0033561 regulation of water loss via skin 6.455358e-6
GO:0046039 GTP metabolic process 7.007592e-6
GO:0051641 cellular localization 7.364990e-6
GO:0001953 negative regulation of cell-matrix adhesion 7.586606e-6
GO:0051494 negative regulation of cytoskeleton organization 7.659070e-6
GO:0015705 iodide transport 8.052872e-6
GO:0001775 cell activation 8.269655e-6
GO:0031347 regulation of defense response 9.100673e-6
GO:0065009 regulation of molecular function 9.441228e-6
GO:0045410 positive regulation of interleukin-6 biosynthetic process 9.753657e-6
GO:0071786 endoplasmic reticulum tubular network organization 1.004196e-5
GO:0002088 lens development in camera-type eye 1.016885e-5
GO:0009888 tissue development 1.023020e-5
GO:0009988 cell-cell recognition 1.042520e-5
GO:0051128 regulation of cellular component organization 1.063717e-5
GO:0030155 regulation of cell adhesion 1.109635e-5
GO:0050790 regulation of catalytic activity 1.117189e-5
GO:0042446 hormone biosynthetic process 1.121585e-5
GO:0080134 regulation of response to stress 1.123170e-5
GO:0045184 establishment of protein localization 1.146555e-5
GO:0072595 maintenance of protein localization to organelle 1.177771e-5
GO:0030154 cell differentiation 1.247619e-5
GO:0021571 rhombomere 5 development 1.258227e-5
GO:0050794 regulation of cellular process 1.316846e-5
GO:0070887 cellular response to chemical stimulus 1.379262e-5
GO:0018958 phenol-containing compound metabolic process 1.383282e-5
GO:0019933 cAMP-mediated signaling 1.396794e-5
GO:0008544 epidermis development 1.426051e-5
GO:0032938 negative regulation of translation in response to oxidative stress 1.437359e-5
GO:0030799 regulation of cyclic nucleotide metabolic process 1.441577e-5
GO:0045006 DNA deamination 1.563567e-5
GO:0007191 activation of adenylate cyclase activity by dopamine receptor signaling pathway 1.570841e-5
GO:0046651 lymphocyte proliferation 1.625330e-5
GO:0048294 negative regulation of isotype switching to IgE isotypes 1.682738e-5
GO:0042461 photoreceptor cell development 1.804551e-5
GO:0006810 transport 1.818091e-5
GO:0002456 T cell mediated immunity 1.853072e-5
GO:0044093 positive regulation of molecular function 1.917674e-5
GO:0015889 cobalamin transport 1.965591e-5
GO:0006935 chemotaxis 1.971834e-5
GO:0050764 regulation of phagocytosis 2.143411e-5
GO:0010646 regulation of cell communication 2.216559e-5
GO:0035270 endocrine system development 2.315554e-5
GO:0032320 positive regulation of Ras GTPase activity 2.383691e-5
GO:0002708 positive regulation of lymphocyte mediated immunity 2.481428e-5
GO:2000026 regulation of multicellular organismal development 2.516126e-5
GO:0051234 establishment of localization 2.528793e-5
GO:0032943 mononuclear cell proliferation 2.585807e-5
GO:0048521 negative regulation of behavior 2.599700e-5
GO:0046463 acylglycerol biosynthetic process 2.663209e-5
GO:0043010 camera-type eye development 2.742382e-5
GO:0006140 regulation of nucleotide metabolic process 2.773217e-5
GO:0032368 regulation of lipid transport 2.798266e-5
GO:0046755 non-lytic virus budding 2.845416e-5
GO:0060341 regulation of cellular localization 2.908157e-5
GO:0010765 positive regulation of sodium ion transport 2.948480e-5
GO:0006956 complement activation 2.955885e-5
GO:0035690 cellular response to drug 2.958764e-5
GO:0030217 T cell differentiation 3.021941e-5
GO:0090003 regulation of establishment of protein localization in plasma membrane 3.051608e-5
GO:0009653 anatomical structure morphogenesis 3.086053e-5
GO:0007190 activation of adenylate cyclase activity 3.169257e-5
GO:0050663 cytokine secretion 3.334812e-5
GO:0090273 regulation of somatostatin secretion 3.437419e-5
GO:0001817 regulation of cytokine production 3.488433e-5
GO:0065007 biological regulation 3.497084e-5
GO:0031394 positive regulation of prostaglandin biosynthetic process 3.515199e-5
GO:0071466 cellular response to xenobiotic stimulus 3.531843e-5
GO:0051239 regulation of multicellular organismal process 3.534403e-5
GO:0050808 synapse organization 3.774354e-5
GO:0070206 protein trimerization 3.822147e-5
GO:0002864 regulation of acute inflammatory response to antigenic stimulus 3.897223e-5
GO:0042537 benzene-containing compound metabolic process 3.909810e-5
GO:0006805 xenobiotic metabolic process 3.969776e-5
GO:0046504 glycerol ether biosynthetic process 3.991282e-5
GO:0044281 small molecule metabolic process 4.100101e-5
GO:0043154 negative regulation of caspase activity 4.114292e-5
GO:0019432 triglyceride biosynthetic process 4.148659e-5
GO:0007029 endoplasmic reticulum organization 4.326166e-5
GO:0032851 positive regulation of Rab GTPase activity 4.440055e-5
GO:0009966 regulation of signal transduction 4.510691e-5
GO:0019935 cyclic-nucleotide-mediated signaling 4.588019e-5
GO:0071622 regulation of granulocyte chemotaxis 4.609789e-5
GO:0042346 positive regulation of NF-kappaB import into nucleus 4.652028e-5
GO:0032916 positive regulation of transforming growth factor beta3 production 4.669377e-5
GO:0090201 negative regulation of release of cytochrome c from mitochondria 4.724647e-5
GO:0060249 anatomical structure homeostasis 4.842662e-5
GO:0007043 cell-cell junction assembly 4.848804e-5
GO:0007292 female gamete generation 4.908138e-5
GO:0038003 opioid receptor signaling pathway 4.936786e-5
GO:0006629 lipid metabolic process 4.993196e-5
GO:0018149 peptide cross-linking 5.014018e-5
GO:0002455 humoral immune response mediated by circulating immunoglobulin 5.138595e-5
GO:0030814 regulation of cAMP metabolic process 5.158163e-5
GO:0019216 regulation of lipid metabolic process 5.162478e-5
GO:0031281 positive regulation of cyclase activity 5.493730e-5
GO:0051349 positive regulation of lyase activity 5.691214e-5
GO:0070661 leukocyte proliferation 5.763747e-5
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 5.853829e-5
GO:0010034 response to acetate 5.853829e-5
GO:0042108 positive regulation of cytokine biosynthetic process 6.050085e-5
GO:0048469 cell maturation 6.179853e-5
GO:2000191 regulation of fatty acid transport 6.222136e-5
GO:0009894 regulation of catabolic process 6.224827e-5
GO:0071260 cellular response to mechanical stimulus 6.348725e-5
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 6.433129e-5
GO:0010574 regulation of vascular endothelial growth factor production 6.457006e-5
GO:0070201 regulation of establishment of protein localization 6.723012e-5
GO:0010639 negative regulation of organelle organization 6.926022e-5
GO:0070163 regulation of adiponectin secretion 6.995524e-5
GO:0030728 ovulation 7.125637e-5
GO:0033617 mitochondrial respiratory chain complex IV assembly 7.153544e-5
GO:0050727 regulation of inflammatory response 7.175597e-5
GO:0060429 epithelium development 7.175955e-5
GO:0071310 cellular response to organic substance 7.200653e-5
GO:0045762 positive regulation of adenylate cyclase activity 7.223118e-5
GO:0048709 oligodendrocyte differentiation 7.387318e-5
GO:0001525 angiogenesis 7.431879e-5
GO:0009410 response to xenobiotic stimulus 7.443467e-5
GO:0043085 positive regulation of catalytic activity 7.484146e-5
GO:0006620 posttranslational protein targeting to membrane 7.528042e-5
GO:0042512 negative regulation of tyrosine phosphorylation of Stat1 protein 7.528042e-5
GO:0015966 diadenosine tetraphosphate biosynthetic process 7.659548e-5
GO:0071345 cellular response to cytokine stimulus 8.131703e-5
GO:0032066 nucleolus to nucleoplasm transport 8.179299e-5
GO:0070105 positive regulation of interleukin-6-mediated signaling pathway 8.179299e-5
GO:0071675 regulation of mononuclear cell migration 8.234875e-5
GO:0019932 second-messenger-mediated signaling 8.308609e-5
GO:0007289 spermatid nucleus differentiation 8.350849e-5
GO:0042574 retinal metabolic process 8.551227e-5
GO:0043374 CD8-positive, alpha-beta T cell differentiation 8.735758e-5
GO:0021553 olfactory nerve development 9.485714e-5
GO:0051050 positive regulation of transport 1.007892e-4
GO:0033043 regulation of organelle organization 1.027293e-4
GO:0043001 Golgi to plasma membrane protein transport 1.028954e-4
GO:0010823 negative regulation of mitochondrion organization 1.028954e-4
GO:0030817 regulation of cAMP biosynthetic process 1.029740e-4
GO:0010759 positive regulation of macrophage chemotaxis 1.033210e-4
GO:0006954 inflammatory response 1.048397e-4
GO:0051240 positive regulation of multicellular organismal process 1.083047e-4
GO:0048293 regulation of isotype switching to IgE isotypes 1.108608e-4
GO:0007600 sensory perception 1.120052e-4
GO:0032231 regulation of actin filament bundle assembly 1.135563e-4
GO:0010951 negative regulation of endopeptidase activity 1.136103e-4
GO:0002250 adaptive immune response 1.163697e-4
GO:0071712 ER-associated misfolded protein catabolic process 1.178129e-4
GO:0050778 positive regulation of immune response 1.183146e-4
GO:0030802 regulation of cyclic nucleotide biosynthetic process 1.209716e-4
GO:0009146 purine nucleoside triphosphate catabolic process 1.266802e-4
GO:0010466 negative regulation of peptidase activity 1.286823e-4
GO:0002829 negative regulation of type 2 immune response 1.290102e-4
GO:0002689 negative regulation of leukocyte chemotaxis 1.290102e-4
GO:0046826 negative regulation of protein export from nucleus 1.290689e-4
GO:0032880 regulation of protein localization 1.303233e-4
GO:0052548 regulation of endopeptidase activity 1.334983e-4
GO:0051492 regulation of stress fiber assembly 1.367174e-4
GO:0060043 regulation of cardiac muscle cell proliferation 1.374779e-4
GO:0046825 regulation of protein export from nucleus 1.388462e-4
GO:0071897 DNA biosynthetic process 1.406423e-4
GO:0030098 lymphocyte differentiation 1.419389e-4
GO:0050922 negative regulation of chemotaxis 1.422312e-4
GO:0006097 glyoxylate cycle 1.445696e-4
GO:0006959 humoral immune response 1.463496e-4
GO:0018879 biphenyl metabolic process 1.479341e-4
GO:0006921 cellular component disassembly involved in apoptosis 1.494100e-4
GO:0031349 positive regulation of defense response 1.494637e-4
GO:0043316 cytotoxic T cell degranulation 1.521503e-4
GO:0006911 phagocytosis, engulfment 1.536109e-4
GO:0030432 peristalsis 1.554852e-4
GO:0040011 locomotion 1.602386e-4
GO:0010754 negative regulation of cGMP-mediated signaling 1.616628e-4
GO:0043652 engulfment of apoptotic cell 1.616628e-4
GO:0002605 negative regulation of dendritic cell antigen processing and presentation 1.616628e-4
GO:0010751 negative regulation of nitric oxide mediated signal transduction 1.616628e-4
GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 1.616628e-4
GO:0043242 negative regulation of protein complex disassembly 1.639800e-4
GO:0050795 regulation of behavior 1.647141e-4
GO:0006426 glycyl-tRNA aminoacylation 1.669895e-4
GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1.675263e-4
GO:0046677 response to antibiotic 1.713892e-4
GO:0030593 neutrophil chemotaxis 1.731743e-4
GO:0009143 nucleoside triphosphate catabolic process 1.751162e-4
GO:0001568 blood vessel development 1.781441e-4
GO:0033600 negative regulation of mammary gland epithelial cell proliferation 1.797068e-4
GO:0010758 regulation of macrophage chemotaxis 1.803509e-4
GO:0009207 purine ribonucleoside triphosphate catabolic process 1.814050e-4
GO:0002253 activation of immune response 1.841635e-4
GO:0051094 positive regulation of developmental process 1.845876e-4
GO:0033124 regulation of GTP catabolic process 1.854985e-4
GO:0009605 response to external stimulus 1.965104e-4
GO:0071285 cellular response to lithium ion 1.968839e-4
GO:0032989 cellular component morphogenesis 1.985838e-4
GO:0035338 long-chain fatty-acyl-CoA biosynthetic process 1.994458e-4
GO:0002673 regulation of acute inflammatory response 2.008070e-4
GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint 2.040083e-4
GO:0050996 positive regulation of lipid catabolic process 2.080974e-4
GO:0048537 mucosal-associated lymphoid tissue development 2.105081e-4
GO:0010033 response to organic substance 2.258899e-4
GO:0030300 regulation of intestinal cholesterol absorption 2.294108e-4
GO:0060355 positive regulation of cell adhesion molecule production 2.346430e-4
GO:0070164 negative regulation of adiponectin secretion 2.346430e-4
GO:0035505 positive regulation of myosin light chain kinase activity 2.346430e-4
GO:0006725 cellular aromatic compound metabolic process 2.396671e-4
GO:0051493 regulation of cytoskeleton organization 2.433572e-4
GO:0001754 eye photoreceptor cell differentiation 2.468054e-4
GO:0071639 positive regulation of monocyte chemotactic protein-1 production 2.493488e-4
GO:0048585 negative regulation of response to stimulus 2.503342e-4
GO:0032731 positive regulation of interleukin-1 beta production 2.628876e-4
GO:0002696 positive regulation of leukocyte activation 2.650831e-4
GO:0048514 blood vessel morphogenesis 2.677616e-4
GO:0040009 regulation of growth rate 2.694561e-4
GO:0016052 carbohydrate catabolic process 2.739175e-4
GO:0001944 vasculature development 2.746233e-4
GO:0046326 positive regulation of glucose import 2.852337e-4
GO:0016486 peptide hormone processing 2.888290e-4
GO:0034589 hydroxyproline transport 2.895110e-4
GO:0000958 mitochondrial mRNA catabolic process 2.895110e-4
GO:0015826 threonine transport 2.895110e-4
GO:0000965 mitochondrial RNA 3'-end processing 2.895110e-4
GO:0000962 positive regulation of mitochondrial RNA catabolic process 2.895110e-4
GO:0045796 negative regulation of intestinal cholesterol absorption 3.004303e-4
GO:0010949 negative regulation of intestinal phytosterol absorption 3.004303e-4
GO:0048741 skeletal muscle fiber development 3.040775e-4
GO:0043087 regulation of GTPase activity 3.042175e-4
GO:0048878 chemical homeostasis 3.061297e-4
GO:0032713 negative regulation of interleukin-4 production 3.145816e-4
GO:0017085 response to insecticide 3.178340e-4
GO:0060847 endothelial cell fate specification 3.313652e-4
GO:0050920 regulation of chemotaxis 3.319699e-4
GO:0001659 temperature homeostasis 3.351513e-4
GO:0007189 activation of adenylate cyclase activity by G-protein signaling pathway 3.376401e-4
GO:2000116 regulation of cysteine-type endopeptidase activity 3.385271e-4
GO:0030182 neuron differentiation 3.482698e-4
GO:0007155 cell adhesion 3.517396e-4
GO:0006637 acyl-CoA metabolic process 3.523195e-4
GO:0046949 fatty-acyl-CoA biosynthetic process 3.568882e-4
GO:0032369 negative regulation of lipid transport 3.635196e-4
GO:0031058 positive regulation of histone modification 3.637077e-4
GO:0051930 regulation of sensory perception of pain 3.691055e-4
GO:0006082 organic acid metabolic process 3.707936e-4
GO:0000902 cell morphogenesis 3.726398e-4
GO:0006014 D-ribose metabolic process 3.727702e-4
GO:0008283 cell proliferation 3.731723e-4
GO:0050867 positive regulation of cell activation 3.758537e-4
GO:0002711 positive regulation of T cell mediated immunity 3.799656e-4
GO:0031536 positive regulation of exit from mitosis 3.843169e-4
GO:0014050 negative regulation of glutamate secretion 3.894053e-4
GO:0048592 eye morphogenesis 3.929825e-4
GO:0051130 positive regulation of cellular component organization 3.936005e-4
GO:0046415 urate metabolic process 3.944918e-4
GO:0051346 negative regulation of hydrolase activity 3.965892e-4
GO:0022409 positive regulation of cell-cell adhesion 4.007124e-4
GO:0031279 regulation of cyclase activity 4.012077e-4
GO:0034201 response to oleic acid 4.121104e-4
GO:0019725 cellular homeostasis 4.191230e-4
GO:0030855 epithelial cell differentiation 4.338901e-4
GO:0031424 keratinization 4.359952e-4
GO:0044057 regulation of system process 4.370504e-4
GO:0009154 purine ribonucleotide catabolic process 4.392294e-4
GO:0071229 cellular response to acid 4.422112e-4
GO:0031329 regulation of cellular catabolic process 4.447376e-4
GO:0045017 glycerolipid biosynthetic process 4.460033e-4
GO:0006950 response to stress 4.510158e-4
GO:0044087 regulation of cellular component biogenesis 4.544011e-4
GO:0048646 anatomical structure formation involved in morphogenesis 4.577460e-4
GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production 4.624668e-4
GO:0001910 regulation of leukocyte mediated cytotoxicity 4.640137e-4
GO:0015959 diadenosine polyphosphate metabolic process 4.641558e-4
GO:0055021 regulation of cardiac muscle tissue growth 4.692867e-4
GO:0060022 hard palate development 4.721004e-4
GO:0035036 sperm-egg recognition 4.924212e-4
GO:0051339 regulation of lyase activity 4.998492e-4
GO:0033129 positive regulation of histone phosphorylation 5.019513e-4
GO:0009261 ribonucleotide catabolic process 5.054336e-4
GO:0007188 G-protein signaling, coupled to cAMP nucleotide second messenger 5.110655e-4
GO:0009408 response to heat 5.208829e-4
GO:0046883 regulation of hormone secretion 5.218606e-4
GO:0046530 photoreceptor cell differentiation 5.266405e-4
GO:0046473 phosphatidic acid metabolic process 5.319590e-4
GO:0035284 brain segmentation 5.366899e-4
GO:0007187 G-protein signaling, coupled to cyclic nucleotide second messenger 5.421336e-4
GO:0042851 L-alanine metabolic process 5.477952e-4
GO:0045087 innate immune response 5.547531e-4
GO:0022603 regulation of anatomical structure morphogenesis 5.567446e-4
GO:0000904 cell morphogenesis involved in differentiation 5.610546e-4
GO:0006066 alcohol metabolic process 5.610688e-4
GO:0045047 protein targeting to ER 5.640255e-4
GO:0030212 hyaluronan metabolic process 5.648414e-4
GO:0030837 negative regulation of actin filament polymerization 5.677176e-4
GO:0015825 L-serine transport 5.738204e-4
GO:0051835 positive regulation of synapse structural plasticity 5.803689e-4
GO:0043163 cell envelope organization 5.803689e-4
GO:0008616 queuosine biosynthetic process 5.861770e-4
GO:0032956 regulation of actin cytoskeleton organization 5.872861e-4
GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 5.919261e-4
GO:0007528 neuromuscular junction development 6.005991e-4
GO:0023057 negative regulation of signaling 6.084468e-4
GO:0051574 positive regulation of histone H3-K9 methylation 6.166346e-4
GO:0044085 cellular component biogenesis 6.181023e-4
GO:0007026 negative regulation of microtubule depolymerization 6.195709e-4
GO:0022607 cellular component assembly 6.283883e-4
GO:0032910 regulation of transforming growth factor beta3 production 6.323754e-4
GO:0060695 negative regulation of cholesterol transporter activity 6.388101e-4
GO:0010648 negative regulation of cell communication 6.410094e-4
GO:0015698 inorganic anion transport 6.416939e-4
GO:0032103 positive regulation of response to external stimulus 6.471053e-4
GO:0002819 regulation of adaptive immune response 6.526804e-4
GO:0032854 positive regulation of Rap GTPase activity 6.568623e-4
GO:0048871 multicellular organismal homeostasis 6.584919e-4
GO:0060045 positive regulation of cardiac muscle cell proliferation 6.737941e-4
GO:0071236 cellular response to antibiotic 6.747661e-4
GO:0045760 positive regulation of action potential 6.747661e-4
GO:0051049 regulation of transport 6.774452e-4
GO:0090004 positive regulation of establishment of protein localization in plasma membrane 6.858265e-4
GO:0045761 regulation of adenylate cyclase activity 6.949107e-4
GO:0033632 regulation of cell-cell adhesion mediated by integrin 7.036661e-4
GO:0045646 regulation of erythrocyte differentiation 7.118131e-4
GO:0045161 neuronal ion channel clustering 7.224282e-4
GO:0009628 response to abiotic stimulus 7.227975e-4
GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway 7.268046e-4
GO:0032763 regulation of mast cell cytokine production 7.360318e-4
GO:0048041 focal adhesion assembly 7.466628e-4
GO:0009056 catabolic process 7.563061e-4
GO:0071637 regulation of monocyte chemotactic protein-1 production 7.849820e-4
GO:0002684 positive regulation of immune system process 8.143269e-4
GO:0046631 alpha-beta T cell activation 8.478384e-4
GO:0034340 response to type I interferon 8.532271e-4
GO:0032673 regulation of interleukin-4 production 8.917342e-4
GO:0052547 regulation of peptidase activity 8.957542e-4
GO:0010638 positive regulation of organelle organization 9.157401e-4
GO:0045070 positive regulation of viral genome replication 9.310412e-4
GO:0007214 gamma-aminobutyric acid signaling pathway 9.419214e-4
GO:0048541 Peyer's patch development 9.499197e-4
GO:0007193 inhibition of adenylate cyclase activity by G-protein signaling pathway 9.576791e-4
GO:0016337 cell-cell adhesion 9.604378e-4
GO:0006032 chitin catabolic process 1.000644e-3
GO:0051345 positive regulation of hydrolase activity 1.014425e-3
GO:0034764 positive regulation of transmembrane transport 1.016193e-3
GO:0042127 regulation of cell proliferation 1.028011e-3
GO:0006461 protein complex assembly 1.029783e-3
GO:0006575 cellular modified amino acid metabolic process 1.033117e-3
GO:0050919 negative chemotaxis 1.040174e-3
GO:0006195 purine nucleotide catabolic process 1.044675e-3
GO:0000731 DNA synthesis involved in DNA repair 1.047553e-3
GO:0048519 negative regulation of biological process 1.052366e-3
GO:0007416 synapse assembly 1.053196e-3
GO:0070271 protein complex biogenesis 1.054358e-3
GO:0032743 positive regulation of interleukin-2 production 1.066957e-3
GO:0001666 response to hypoxia 1.068470e-3
GO:0051704 multi-organism process 1.092140e-3
GO:0031114 regulation of microtubule depolymerization 1.092349e-3
GO:0019693 ribose phosphate metabolic process 1.114487e-3
GO:0060166 olfactory pit development 1.123082e-3
GO:0019695 choline metabolic process 1.128665e-3
GO:0006893 Golgi to plasma membrane transport 1.147636e-3
GO:0016525 negative regulation of angiogenesis 1.153906e-3
GO:0034762 regulation of transmembrane transport 1.157964e-3
GO:0060326 cell chemotaxis 1.172669e-3
GO:0021514 ventral spinal cord interneuron differentiation 1.180470e-3
GO:0002443 leukocyte mediated immunity 1.183489e-3
GO:0051495 positive regulation of cytoskeleton organization 1.184032e-3
GO:0007268 synaptic transmission 1.185015e-3
GO:0045647 negative regulation of erythrocyte differentiation 1.197389e-3
GO:0055082 cellular chemical homeostasis 1.201314e-3
GO:0051129 negative regulation of cellular component organization 1.215353e-3
GO:0044255 cellular lipid metabolic process 1.223781e-3
GO:0031644 regulation of neurological system process 1.225829e-3
GO:0007204 elevation of cytosolic calcium ion concentration 1.231839e-3
GO:0010755 regulation of plasminogen activation 1.270994e-3
GO:0045408 regulation of interleukin-6 biosynthetic process 1.290154e-3
GO:0051051 negative regulation of transport 1.290445e-3
GO:0042063 gliogenesis 1.294590e-3
GO:0042307 positive regulation of protein import into nucleus 1.304229e-3
GO:0006680 glucosylceramide catabolic process 1.316911e-3


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0046627 negative regulation of insulin receptor signaling pathway 1.282270e-15
GO:0050896 response to stimulus 9.924003e-13
GO:0035802 adrenal cortex formation 9.367306e-12
GO:0051180 vitamin transport 1.084091e-11
GO:0046626 regulation of insulin receptor signaling pathway 9.804896e-11
GO:0006950 response to stress 8.030283e-10
GO:0032846 positive regulation of homeostatic process 1.484203e-9
GO:0031100 organ regeneration 1.912120e-9
GO:0070168 negative regulation of biomineral tissue development 2.713651e-9
GO:0072302 negative regulation of metanephric glomerular mesangial cell proliferation 4.578375e-9
GO:2001076 positive regulation of metanephric ureteric bud development 4.578375e-9
GO:0007356 thorax and anterior abdomen determination 4.578375e-9
GO:0030279 negative regulation of ossification 6.231913e-9
GO:0048814 regulation of dendrite morphogenesis 1.324128e-8
GO:0030502 negative regulation of bone mineralization 1.513529e-8
GO:0032501 multicellular organismal process 1.770830e-8
GO:0032502 developmental process 2.434902e-8
GO:0031099 regeneration 3.649988e-8
GO:0072284 metanephric S-shaped body morphogenesis 5.012883e-8
GO:0072278 metanephric comma-shaped body morphogenesis 5.012883e-8
GO:0023052 signaling 8.065820e-8
GO:0050773 regulation of dendrite development 9.031383e-8
GO:0048583 regulation of response to stimulus 9.576017e-8
GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway 1.126985e-7
GO:0007154 cell communication 1.500891e-7
GO:0007354 zygotic determination of anterior/posterior axis, embryo 1.841700e-7
GO:0045780 positive regulation of bone resorption 1.882004e-7
GO:0060923 cardiac muscle cell fate commitment 2.036609e-7
GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling 2.613894e-7
GO:0006952 defense response 2.986983e-7
GO:0007275 multicellular organismal development 3.251832e-7
GO:0001542 ovulation from ovarian follicle 3.463273e-7
GO:0046649 lymphocyte activation 3.654545e-7
GO:0048856 anatomical structure development 3.947620e-7
GO:0006420 arginyl-tRNA aminoacylation 4.942287e-7
GO:0045807 positive regulation of endocytosis 5.025633e-7
GO:0006955 immune response 6.068436e-7
GO:0010873 positive regulation of cholesterol esterification 6.502125e-7
GO:0042448 progesterone metabolic process 6.577852e-7
GO:0034105 positive regulation of tissue remodeling 8.577611e-7
GO:0002376 immune system process 9.412014e-7
GO:0010872 regulation of cholesterol esterification 9.453399e-7
GO:0045065 cytotoxic T cell differentiation 1.015930e-6
GO:0010951 negative regulation of endopeptidase activity 1.280619e-6
GO:0070837 dehydroascorbic acid transport 1.339896e-6
GO:0050766 positive regulation of phagocytosis 1.426795e-6
GO:0072166 posterior mesonephric tubule development 1.470166e-6
GO:0009258 10-formyltetrahydrofolate catabolic process 1.624850e-6
GO:0045911 positive regulation of DNA recombination 2.178885e-6
GO:0030728 ovulation 2.179367e-6
GO:0045188 regulation of circadian sleep/wake cycle, non-REM sleep 2.194659e-6
GO:0031640 killing of cells of other organism 2.215504e-6
GO:0051239 regulation of multicellular organismal process 2.797533e-6
GO:0072301 regulation of metanephric glomerular mesangial cell proliferation 3.029566e-6
GO:0048731 system development 3.103538e-6
GO:0002077 acrosome matrix dispersal 3.192638e-6
GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep 3.496462e-6
GO:0051716 cellular response to stimulus 3.984246e-6
GO:0051240 positive regulation of multicellular organismal process 4.229893e-6
GO:0048584 positive regulation of response to stimulus 4.298541e-6
GO:0002385 mucosal immune response 4.973526e-6
GO:0034370 triglyceride-rich lipoprotein particle remodeling 5.897979e-6
GO:0051883 killing of cells in other organism involved in symbiotic interaction 5.897979e-6
GO:0032957 inositol trisphosphate metabolic process 6.547369e-6
GO:0006982 response to lipid hydroperoxide 6.720784e-6
GO:0060539 diaphragm development 7.777949e-6
GO:0010898 positive regulation of triglyceride catabolic process 7.789745e-6
GO:0050775 positive regulation of dendrite morphogenesis 8.525678e-6
GO:0001944 vasculature development 8.788784e-6
GO:0046850 regulation of bone remodeling 9.075072e-6
GO:0019430 removal of superoxide radicals 9.108173e-6
GO:0002251 organ or tissue specific immune response 9.292100e-6
GO:0044243 multicellular organismal catabolic process 9.331399e-6
GO:0000305 response to oxygen radical 9.352343e-6
GO:0072539 T-helper 17 cell differentiation 9.784431e-6
GO:0001516 prostaglandin biosynthetic process 9.888913e-6
GO:0019836 hemolysis by symbiont of host erythrocytes 1.058248e-5
GO:0055090 acylglycerol homeostasis 1.061786e-5
GO:0007159 leukocyte cell-cell adhesion 1.066049e-5
GO:0001701 in utero embryonic development 1.102770e-5
GO:0032844 regulation of homeostatic process 1.124584e-5
GO:0018158 protein oxidation 1.142038e-5
GO:0033194 response to hydroperoxide 1.150232e-5
GO:0008595 anterior/posterior axis specification, embryo 1.387825e-5
GO:0045577 regulation of B cell differentiation 1.390244e-5
GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway 1.449478e-5
GO:0019371 cyclooxygenase pathway 1.590412e-5
GO:0007281 germ cell development 1.602837e-5
GO:0006633 fatty acid biosynthetic process 1.670361e-5
GO:0006953 acute-phase response 1.685248e-5
GO:0044003 modification by symbiont of host morphology or physiology 2.026607e-5
GO:0007165 signal transduction 2.047628e-5
GO:0042744 hydrogen peroxide catabolic process 2.118812e-5
GO:0060627 regulation of vesicle-mediated transport 2.146423e-5
GO:0048265 response to pain 2.256445e-5
GO:0032817 regulation of natural killer cell proliferation 2.473489e-5
GO:0014034 neural crest cell fate commitment 2.513400e-5
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis 2.515839e-5
GO:0050748 negative regulation of lipoprotein metabolic process 2.837833e-5
GO:0060421 positive regulation of heart growth 2.936633e-5
GO:0001568 blood vessel development 3.012197e-5
GO:0072273 metanephric nephron morphogenesis 3.057297e-5
GO:0045926 negative regulation of growth 3.325819e-5
GO:2000195 negative regulation of female gonad development 3.366799e-5
GO:0002440 production of molecular mediator of immune response 3.377899e-5
GO:0003006 developmental process involved in reproduction 3.397250e-5
GO:0060911 cardiac cell fate commitment 3.612009e-5
GO:0090074 negative regulation of protein homodimerization activity 3.815481e-5
GO:0051659 maintenance of mitochondrion location 3.843069e-5
GO:0042753 positive regulation of circadian rhythm 3.843069e-5
GO:0001658 branching involved in ureteric bud morphogenesis 4.041618e-5
GO:0023051 regulation of signaling 4.209327e-5
GO:0071436 sodium ion export 4.460615e-5
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 4.460615e-5
GO:0045321 leukocyte activation 4.481435e-5
GO:0051006 positive regulation of lipoprotein lipase activity 4.527183e-5
GO:2000020 positive regulation of male gonad development 4.936165e-5
GO:0048513 organ development 5.130514e-5
GO:0034103 regulation of tissue remodeling 5.382978e-5
GO:0050865 regulation of cell activation 5.409395e-5
GO:0040008 regulation of growth 5.416755e-5
GO:0072125 negative regulation of glomerular mesangial cell proliferation 5.600119e-5
GO:0090049 regulation of cell migration involved in sprouting angiogenesis 5.631098e-5
GO:0045938 positive regulation of circadian sleep/wake cycle, sleep 5.713468e-5
GO:0042346 positive regulation of NF-kappaB import into nucleus 5.861341e-5
GO:0019358 nicotinate nucleotide salvage 5.942473e-5
GO:0016337 cell-cell adhesion 5.970797e-5
GO:0048268 clathrin coat assembly 6.170400e-5
GO:0061032 visceral serous pericardium development 6.264916e-5
GO:0002526 acute inflammatory response 6.348027e-5
GO:0050746 regulation of lipoprotein metabolic process 6.624245e-5
GO:0030100 regulation of endocytosis 7.030475e-5
GO:0035095 behavioral response to nicotine 7.079931e-5
GO:0006901 vesicle coating 7.193737e-5
GO:0032733 positive regulation of interleukin-10 production 7.205091e-5
GO:0050668 positive regulation of homocysteine metabolic process 7.479944e-5
GO:0045963 negative regulation of dopamine metabolic process 7.479944e-5
GO:2000194 regulation of female gonad development 7.594919e-5
GO:0070904 transepithelial L-ascorbic acid transport 8.233239e-5
GO:0009311 oligosaccharide metabolic process 8.430967e-5
GO:0002227 innate immune response in mucosa 8.456088e-5
GO:0006760 folic acid-containing compound metabolic process 8.682744e-5
GO:0060395 SMAD protein signal transduction 8.763683e-5
GO:0035117 embryonic arm morphogenesis 8.841543e-5
GO:0051924 regulation of calcium ion transport 8.968929e-5
GO:0032879 regulation of localization 9.327315e-5
GO:0042345 regulation of NF-kappaB import into nucleus 9.442025e-5
GO:0090273 regulation of somatostatin secretion 9.620226e-5
GO:0035104 positive regulation of transcription via sterol regulatory element binding 9.771680e-5
GO:0030838 positive regulation of actin filament polymerization 9.961951e-5
GO:0042908 xenobiotic transport 1.011182e-4
GO:0048609 multicellular organismal reproductive process 1.027585e-4
GO:0006599 phosphagen metabolic process 1.053688e-4
GO:0044130 negative regulation of growth of symbiont in host 1.094845e-4
GO:0050996 positive regulation of lipid catabolic process 1.094845e-4
GO:0045830 positive regulation of isotype switching 1.111499e-4
GO:0070541 response to platinum ion 1.130037e-4
GO:0035590 purinergic nucleotide receptor signaling pathway 1.176437e-4
GO:0002694 regulation of leukocyte activation 1.181768e-4
GO:0006471 protein ADP-ribosylation 1.201460e-4
GO:2000271 positive regulation of fibroblast apoptosis 1.237820e-4
GO:2000270 negative regulation of fibroblast apoptosis 1.237820e-4
GO:0044345 stromal-epithelial cell signaling involved in prostate gland development 1.237820e-4
GO:2000080 negative regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation 1.237820e-4
GO:0045578 negative regulation of B cell differentiation 1.246330e-4
GO:0014043 negative regulation of neuron maturation 1.246330e-4
GO:0051657 maintenance of organelle location 1.296038e-4
GO:0060137 maternal process involved in parturition 1.310665e-4
GO:0009408 response to heat 1.351909e-4
GO:0002377 immunoglobulin production 1.373161e-4
GO:0006941 striated muscle contraction 1.392892e-4
GO:0048266 behavioral response to pain 1.399644e-4
GO:0060732 positive regulation of inositol phosphate biosynthetic process 1.407809e-4
GO:0006693 prostaglandin metabolic process 1.434592e-4
GO:0042110 T cell activation 1.469487e-4
GO:0034445 negative regulation of plasma lipoprotein particle oxidation 1.499287e-4
GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism 1.520197e-4
GO:0006713 glucocorticoid catabolic process 1.568136e-4
GO:0050795 regulation of behavior 1.592927e-4
GO:0051176 positive regulation of sulfur metabolic process 1.630765e-4
GO:0043901 negative regulation of multi-organism process 1.645191e-4
GO:0003166 bundle of His development 1.798484e-4
GO:0009611 response to wounding 1.838503e-4
GO:0010919 regulation of inositol phosphate biosynthetic process 1.940884e-4
GO:2000079 regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation 1.958985e-4
GO:0071380 cellular response to prostaglandin E stimulus 1.958985e-4
GO:0006994 positive regulation of transcription via sterol regulatory element binding involved in ER-nuclear sterol response pathway 1.958985e-4
GO:0000303 response to superoxide 1.963600e-4
GO:0003161 cardiac conduction system development 1.972523e-4
GO:0050850 positive regulation of calcium-mediated signaling 1.986530e-4
GO:0034372 very-low-density lipoprotein particle remodeling 1.993279e-4
GO:0045124 regulation of bone resorption 2.027594e-4
GO:0033600 negative regulation of mammary gland epithelial cell proliferation 2.061984e-4
GO:0072015 glomerular visceral epithelial cell development 2.128582e-4
GO:0014029 neural crest formation 2.128582e-4
GO:0030278 regulation of ossification 2.163602e-4
GO:0070389 chaperone cofactor-dependent protein refolding 2.176597e-4
GO:0033239 negative regulation of cellular amine metabolic process 2.176597e-4
GO:0061008 hepaticobiliary system development 2.220528e-4
GO:0051127 positive regulation of actin nucleation 2.233292e-4
GO:0019953 sexual reproduction 2.281449e-4
GO:0001889 liver development 2.373299e-4
GO:0048610 cellular process involved in reproduction 2.391434e-4
GO:0072124 regulation of glomerular mesangial cell proliferation 2.428466e-4
GO:0006810 transport 2.451084e-4
GO:0043647 inositol phosphate metabolic process 2.471600e-4
GO:0002639 positive regulation of immunoglobulin production 2.496718e-4
GO:0002683 negative regulation of immune system process 2.502506e-4
GO:0001775 cell activation 2.524522e-4
GO:0010033 response to organic substance 2.540280e-4
GO:0034442 regulation of lipoprotein oxidation 2.552720e-4
GO:0051234 establishment of localization 2.556599e-4
GO:0030574 collagen catabolic process 2.558262e-4
GO:0008284 positive regulation of cell proliferation 2.558577e-4
GO:0014829 vascular smooth muscle contraction 2.561432e-4
GO:0060231 mesenchymal to epithelial transition 2.626745e-4
GO:0060136 embryonic process involved in female pregnancy 2.641764e-4
GO:2000018 regulation of male gonad development 2.641764e-4
GO:0060133 somatotropin secreting cell development 2.714882e-4
GO:0034553 mitochondrial respiratory chain complex II assembly 2.714882e-4
GO:0010845 positive regulation of reciprocal meiotic recombination 2.714882e-4
GO:0045187 regulation of circadian sleep/wake cycle, sleep 2.726864e-4
GO:0008207 C21-steroid hormone metabolic process 2.829022e-4
GO:0048304 positive regulation of isotype switching to IgG isotypes 2.901428e-4
GO:0015669 gas transport 2.910892e-4
GO:0006590 thyroid hormone generation 3.136061e-4
GO:0051049 regulation of transport 3.353976e-4
GO:0051607 defense response to virus 3.363508e-4
GO:0050764 regulation of phagocytosis 3.373273e-4
GO:0045137 development of primary sexual characteristics 3.419895e-4
GO:0001906 cell killing 3.455113e-4
GO:0007292 female gamete generation 3.489879e-4
GO:0007341 penetration of zona pellucida 3.552450e-4
GO:0009966 regulation of signal transduction 3.676079e-4
GO:0009948 anterior/posterior axis specification 3.731745e-4
GO:0051125 regulation of actin nucleation 3.747246e-4
GO:0007271 synaptic transmission, cholinergic 3.756613e-4
GO:2000466 negative regulation of glycogen (starch) synthase activity 3.776702e-4
GO:0006107 oxaloacetate metabolic process 3.924081e-4
GO:0072358 cardiovascular system development 3.962670e-4
GO:0002706 regulation of lymphocyte mediated immunity 3.978943e-4
GO:0045588 positive regulation of gamma-delta T cell differentiation 4.076797e-4
GO:0042993 positive regulation of transcription factor import into nucleus 4.099524e-4
GO:0045663 positive regulation of myoblast differentiation 4.132142e-4
GO:0042127 regulation of cell proliferation 4.188453e-4
GO:0045766 positive regulation of angiogenesis 4.204986e-4
GO:0065007 biological regulation 4.207469e-4
GO:0006103 2-oxoglutarate metabolic process 4.280693e-4
GO:0007167 enzyme linked receptor protein signaling pathway 4.343493e-4
GO:0050727 regulation of inflammatory response 4.361813e-4
GO:0048537 mucosal-associated lymphoid tissue development 4.376866e-4
GO:0010591 regulation of lamellipodium assembly 4.376866e-4
GO:0006688 glycosphingolipid biosynthetic process 4.386396e-4
GO:0090362 positive regulation of platelet-derived growth factor production 4.429590e-4
GO:0090336 positive regulation of brown fat cell differentiation 4.429590e-4
GO:0008208 C21-steroid hormone catabolic process 4.429590e-4
GO:0090271 positive regulation of fibroblast growth factor production 4.429590e-4
GO:0016192 vesicle-mediated transport 4.432817e-4
GO:0008054 cyclin catabolic process 4.436484e-4
GO:0048514 blood vessel morphogenesis 4.547112e-4
GO:0007276 gamete generation 4.560001e-4
GO:0060762 regulation of branching involved in mammary gland duct morphogenesis 4.722572e-4
GO:0009247 glycolipid biosynthetic process 4.878516e-4
GO:0007585 respiratory gaseous exchange 4.968098e-4
GO:0042221 response to chemical stimulus 5.000501e-4
GO:0010896 regulation of triglyceride catabolic process 5.087787e-4
GO:0035645 enteric smooth muscle cell differentiation 5.166526e-4
GO:0007497 posterior midgut development 5.166526e-4
GO:0014041 regulation of neuron maturation 5.242774e-4
GO:2000653 regulation of genetic imprinting 5.347088e-4
GO:0015670 carbon dioxide transport 5.384466e-4
GO:0006491 N-glycan processing 5.422706e-4
GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway 5.808050e-4
GO:0006888 ER to Golgi vesicle-mediated transport 5.827992e-4
GO:0003338 metanephros morphogenesis 5.849731e-4
GO:0006954 inflammatory response 6.275244e-4
GO:0060540 diaphragm morphogenesis 6.303845e-4
GO:0060464 lung lobe formation 6.303845e-4
GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway 6.341216e-4
GO:0001910 regulation of leukocyte mediated cytotoxicity 6.500371e-4
GO:0032819 positive regulation of natural killer cell proliferation 6.654999e-4
GO:0022412 cellular process involved in reproduction in multicellular organism 6.690176e-4
GO:0001912 positive regulation of leukocyte mediated cytotoxicity 6.720083e-4
GO:0032962 positive regulation of inositol trisphosphate biosynthetic process 6.768602e-4
GO:0046070 dGTP metabolic process 6.768602e-4
GO:0061002 negative regulation of dendritic spine morphogenesis 6.768602e-4
GO:0045338 farnesyl diphosphate metabolic process 6.768602e-4
GO:0048520 positive regulation of behavior 6.804951e-4
GO:0010646 regulation of cell communication 6.813925e-4
GO:0051050 positive regulation of transport 6.869770e-4
GO:0007517 muscle organ development 6.893208e-4
GO:0002682 regulation of immune system process 6.895765e-4
GO:0048646 anatomical structure formation involved in morphogenesis 6.927197e-4
GO:0003171 atrioventricular valve development 7.009014e-4
GO:0031347 regulation of defense response 7.036377e-4
GO:0002381 immunoglobulin production involved in immunoglobulin mediated immune response 7.186877e-4
GO:0019233 sensory perception of pain 7.339558e-4
GO:0007166 cell surface receptor linked signaling pathway 7.349815e-4
GO:0090208 positive regulation of triglyceride metabolic process 7.393165e-4
GO:0000003 reproduction 7.578737e-4
GO:0000090 mitotic anaphase 7.701782e-4
GO:0016973 poly(A)+ mRNA export from nucleus 7.701782e-4
GO:0030490 maturation of SSU-rRNA 7.718836e-4
GO:0014821 phasic smooth muscle contraction 7.890195e-4
GO:0034435 cholesterol esterification 7.983396e-4
GO:0043496 regulation of protein homodimerization activity 8.041051e-4
GO:0070167 regulation of biomineral tissue development 8.116879e-4
GO:2000026 regulation of multicellular organismal development 8.342834e-4
GO:0033700 phospholipid efflux 8.590038e-4
GO:2000021 regulation of ion homeostasis 8.827485e-4
GO:0010592 positive regulation of lamellipodium assembly 8.907110e-4
GO:0061138 morphogenesis of a branching epithelium 8.926811e-4
GO:0060055 angiogenesis involved in wound healing 9.084909e-4
GO:0072050 S-shaped body morphogenesis 9.186267e-4
GO:0072049 comma-shaped body morphogenesis 9.186267e-4
GO:0015914 phospholipid transport 9.191714e-4
GO:0001657 ureteric bud development 9.211297e-4
GO:0072283 metanephric renal vesicle morphogenesis 9.304335e-4
GO:0035587 purinergic receptor signaling pathway 9.391836e-4
GO:0050871 positive regulation of B cell activation 9.434431e-4
GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 9.947117e-4
GO:0003181 atrioventricular valve morphogenesis 1.024126e-3
GO:0030500 regulation of bone mineralization 1.078773e-3
GO:0001892 embryonic placenta development 1.089905e-3
GO:0044106 cellular amine metabolic process 1.120339e-3
GO:0006939 smooth muscle contraction 1.124122e-3
GO:0060675 ureteric bud morphogenesis 1.127776e-3
GO:0032958 inositol phosphate biosynthetic process 1.139212e-3
GO:0002268 follicular dendritic cell differentiation 1.172359e-3
GO:0000578 embryonic axis specification 1.191330e-3
GO:0097039 protein linear polyubiquitination 1.195784e-3
GO:0072520 seminiferous tubule development 1.195784e-3
GO:0051383 kinetochore organization 1.203028e-3
GO:0030382 sperm mitochondrion organization 1.203028e-3
GO:0000132 establishment of mitotic spindle orientation 1.230413e-3
GO:0010901 regulation of very-low-density lipoprotein particle remodeling 1.244903e-3
GO:0000018 regulation of DNA recombination 1.290641e-3
GO:0035050 embryonic heart tube development 1.297228e-3
GO:0008202 steroid metabolic process 1.313832e-3
GO:0031341 regulation of cell killing 1.314068e-3
GO:0022414 reproductive process 1.319767e-3
GO:0043519 regulation of myosin II filament organization 1.344574e-3
GO:0070672 response to interleukin-15 1.344574e-3
GO:0043206 fibril organization 1.347317e-3
GO:0001893 maternal placenta development 1.361235e-3
GO:0014826 vein smooth muscle contraction 1.411945e-3
GO:0001911 negative regulation of leukocyte mediated cytotoxicity 1.445708e-3
GO:0033108 mitochondrial respiratory chain complex assembly 1.449067e-3
GO:0006600 creatine metabolic process 1.454014e-3
GO:0002456 T cell mediated immunity 1.455989e-3
GO:0006090 pyruvate metabolic process 1.465085e-3
GO:0046620 regulation of organ growth 1.466735e-3
GO:0006481 C-terminal protein methylation 1.480589e-3
GO:0000461 endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1.480589e-3
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1.480589e-3
GO:0031343 positive regulation of cell killing 1.503197e-3
GO:0008406 gonad development 1.505288e-3
GO:0046653 tetrahydrofolate metabolic process 1.529140e-3
GO:0070460 thyroid-stimulating hormone secretion 1.536673e-3
GO:0048738 cardiac muscle tissue development 1.540125e-3
GO:0060993 kidney morphogenesis 1.550327e-3
GO:0031342 negative regulation of cell killing 1.552960e-3
GO:0008594 photoreceptor cell morphogenesis 1.593210e-3
GO:0061011 hepatic duct development 1.593210e-3
GO:0051641 cellular localization 1.645424e-3
GO:0002920 regulation of humoral immune response 1.651090e-3
GO:0046394 carboxylic acid biosynthetic process 1.685661e-3
GO:0060158 activation of phospholipase C activity by dopamine receptor signaling pathway 1.697588e-3
GO:0042304 regulation of fatty acid biosynthetic process 1.713680e-3
GO:2000507 positive regulation of energy homeostasis 1.731189e-3
GO:0001831 trophectodermal cellular morphogenesis 1.731189e-3
GO:2000253 positive regulation of feeding behavior 1.731189e-3
GO:0009617 response to bacterium 1.740511e-3
GO:0044236 multicellular organismal metabolic process 1.750897e-3
GO:0071560 cellular response to transforming growth factor beta stimulus 1.774591e-3
GO:0010959 regulation of metal ion transport 1.820882e-3
GO:0022410 circadian sleep/wake cycle process 1.840016e-3
GO:0042113 B cell activation 1.853548e-3
GO:0033555 multicellular organismal response to stress 1.858823e-3
GO:0006730 one-carbon metabolic process 1.870367e-3
GO:0060262 negative regulation of N-terminal protein palmitoylation 1.915396e-3
GO:2000009 negative regulation of protein localization at cell surface 1.915396e-3
GO:0021771 lateral geniculate nucleus development 1.915396e-3
GO:0009443 pyridoxal 5'-phosphate salvage 1.915396e-3
GO:0040001 establishment of mitotic spindle localization 1.915592e-3
GO:0071214 cellular response to abiotic stimulus 1.937620e-3
GO:0033554 cellular response to stress 1.967185e-3
GO:0060537 muscle tissue development 1.983500e-3
GO:0030308 negative regulation of cell growth 1.985099e-3
GO:0002637 regulation of immunoglobulin production 1.999329e-3
GO:0031344 regulation of cell projection organization 2.031194e-3
GO:0051382 kinetochore assembly 2.071655e-3
GO:0060252 positive regulation of glial cell proliferation 2.081995e-3
GO:0016554 cytidine to uridine editing 2.086063e-3
GO:0006979 response to oxidative stress 2.104048e-3
GO:0051255 spindle midzone assembly 2.118740e-3
GO:0042592 homeostatic process 2.139374e-3
GO:0001710 mesodermal cell fate commitment 2.185653e-3
GO:0042840 D-glucuronate catabolic process 2.188875e-3
GO:0010667 negative regulation of cardiac muscle cell apoptosis 2.191717e-3
GO:0045747 positive regulation of Notch signaling pathway 2.198779e-3
GO:0051817 modification of morphology or physiology of other organism involved in symbiotic interaction 2.246621e-3
GO:0048535 lymph node development 2.246738e-3
GO:0072077 renal vesicle morphogenesis 2.269136e-3
GO:0071481 cellular response to X-ray 2.345221e-3
GO:0015884 folic acid transport 2.345221e-3
GO:0051649 establishment of localization in cell 2.368221e-3
GO:0048302 regulation of isotype switching to IgG isotypes 2.404990e-3
GO:0032101 regulation of response to external stimulus 2.411763e-3
GO:0046185 aldehyde catabolic process 2.419287e-3
GO:0005989 lactose biosynthetic process 2.446438e-3
GO:0046544 development of secondary male sexual characteristics 2.446438e-3
GO:0045579 positive regulation of B cell differentiation 2.450693e-3
GO:0009312 oligosaccharide biosynthetic process 2.465752e-3
GO:0060056 mammary gland involution 2.477415e-3
GO:0003229 ventricular cardiac muscle tissue development 2.514256e-3
GO:0050864 regulation of B cell activation 2.584066e-3
GO:0003283 atrial septum development 2.599006e-3
GO:0009719 response to endogenous stimulus 2.644347e-3
GO:0050789 regulation of biological process 2.662138e-3
GO:0009988 cell-cell recognition 2.699858e-3
GO:0050848 regulation of calcium-mediated signaling 2.720407e-3
GO:0009725 response to hormone stimulus 2.736791e-3
GO:0044281 small molecule metabolic process 2.737466e-3
GO:0060126 somatotropin secreting cell differentiation 2.741774e-3
GO:0045079 negative regulation of chemokine biosynthetic process 2.741774e-3
GO:0033128 negative regulation of histone phosphorylation 2.824722e-3
GO:0003094 glomerular filtration 2.824722e-3
GO:0042745 circadian sleep/wake cycle 2.874028e-3
GO:0032496 response to lipopolysaccharide 2.892201e-3
GO:0006936 muscle contraction 2.903496e-3
GO:0050866 negative regulation of cell activation 2.912642e-3
GO:0050432 catecholamine secretion 2.926073e-3
GO:0071257 cellular response to electrical stimulus 2.944010e-3
GO:0051179 localization 2.952309e-3
GO:0016553 base conversion or substitution editing 2.954591e-3
GO:0032864 activation of Cdc42 GTPase activity 2.954591e-3
GO:0032653 regulation of interleukin-10 production 2.976955e-3
GO:0007204 elevation of cytosolic calcium ion concentration 2.985564e-3
GO:0007163 establishment or maintenance of cell polarity 2.987364e-3
GO:0006575 cellular modified amino acid metabolic process 2.988536e-3
GO:0070669 response to interleukin-2 3.036297e-3
GO:0060022 hard palate development 3.047068e-3
GO:2000027 regulation of organ morphogenesis 3.113510e-3
GO:0010613 positive regulation of cardiac muscle hypertrophy 3.132606e-3
GO:0046651 lymphocyte proliferation 3.182134e-3
GO:0071305 cellular response to vitamin D 3.184392e-3
GO:0051891 positive regulation of cardioblast differentiation 3.184392e-3
GO:0019054 modulation by virus of host cellular process 3.210535e-3
GO:0001702 gastrulation with mouth forming second 3.369413e-3
GO:0009266 response to temperature stimulus 3.378531e-3
GO:0030098 lymphocyte differentiation 3.378537e-3
GO:0032259 methylation 3.390937e-3
GO:0072028 nephron morphogenesis 3.456666e-3
GO:0003218 cardiac left ventricle formation 3.488595e-3
GO:0001573 ganglioside metabolic process 3.513487e-3
GO:0032472 Golgi calcium ion transport 3.517247e-3
GO:0032468 Golgi calcium ion homeostasis 3.517247e-3
GO:0030026 cellular manganese ion homeostasis 3.517247e-3
GO:0060420 regulation of heart growth 3.525135e-3
GO:0046456 icosanoid biosynthetic process 3.540455e-3
GO:0050873 brown fat cell differentiation 3.540455e-3
GO:0002707 negative regulation of lymphocyte mediated immunity 3.546084e-3
GO:0009628 response to abiotic stimulus 3.594440e-3
GO:0018345 protein palmitoylation 3.595658e-3
GO:0001675 acrosome assembly 3.598207e-3
GO:0002252 immune effector process 3.638379e-3
GO:0071371 cellular response to gonadotropin stimulus 3.670112e-3
GO:0006344 maintenance of chromatin silencing 3.689123e-3
GO:2000522 positive regulation of immunological synapse formation 3.691243e-3
GO:0072500 negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor 3.691243e-3
GO:0010918 positive regulation of mitochondrial membrane potential 3.691243e-3
GO:0050925 negative regulation of negative chemotaxis 3.731049e-3
GO:0048241 epinephrine transport 3.731070e-3
GO:0051004 regulation of lipoprotein lipase activity 3.735166e-3
GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 3.765153e-3
GO:0001915 negative regulation of T cell mediated cytotoxicity 3.779006e-3
GO:0006900 membrane budding 3.811709e-3
GO:0048630 skeletal muscle tissue growth 3.812768e-3
GO:0006868 glutamine transport 3.812768e-3
GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway 3.820284e-3
GO:0035335 peptidyl-tyrosine dephosphorylation 3.827519e-3
GO:0019439 aromatic compound catabolic process 3.874073e-3
GO:0046622 positive regulation of organ growth 3.973917e-3
GO:0051249 regulation of lymphocyte activation 3.974832e-3
GO:0016310 phosphorylation 4.000181e-3
GO:0070849 response to epidermal growth factor stimulus 4.064082e-3
GO:0048242 epinephrine secretion 4.096357e-3
GO:0002689 negative regulation of leukocyte chemotaxis 4.096357e-3
GO:0042098 T cell proliferation 4.120886e-3
GO:0002820 negative regulation of adaptive immune response 4.126005e-3
GO:0090276 regulation of peptide hormone secretion 4.162827e-3
GO:0050796 regulation of insulin secretion 4.210090e-3
GO:0072511 divalent inorganic cation transport 4.231899e-3
GO:0010647 positive regulation of cell communication 4.293947e-3
GO:0001821 histamine secretion 4.318980e-3
GO:0050912 detection of chemical stimulus involved in sensory perception of taste 4.366347e-3
GO:2000117 negative regulation of cysteine-type endopeptidase activity 4.398476e-3
GO:0006520 cellular amino acid metabolic process 4.414776e-3
GO:0022603 regulation of anatomical structure morphogenesis 4.425143e-3