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Novel motif:6

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name:motif6_AAGACT

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0006950 response to stress 3.013363e-32
GO:0009611 response to wounding 9.956981e-30
GO:0050896 response to stimulus 4.222681e-29
GO:0032501 multicellular organismal process 2.844920e-24
GO:0030168 platelet activation 4.207682e-21
GO:0032502 developmental process 6.732643e-21
GO:0009987 cellular process 6.811661e-21
GO:0050794 regulation of cellular process 7.110139e-21
GO:0042060 wound healing 1.349589e-20
GO:0051716 cellular response to stimulus 1.421063e-20
GO:0065007 biological regulation 6.229882e-20
GO:0048513 organ development 1.043606e-19
GO:0050789 regulation of biological process 1.263640e-19
GO:0002576 platelet degranulation 9.719479e-19
GO:0048856 anatomical structure development 1.131207e-18
GO:0065008 regulation of biological quality 1.689314e-18
GO:0001775 cell activation 2.755466e-18
GO:0055013 cardiac muscle cell development 6.167854e-18
GO:0006954 inflammatory response 1.685224e-17
GO:0050793 regulation of developmental process 2.980133e-17
GO:0009888 tissue development 3.262791e-17
GO:0051179 localization 6.269522e-17
GO:0006952 defense response 6.384939e-17
GO:0042221 response to chemical stimulus 6.501779e-17
GO:0007165 signal transduction 8.735498e-17
GO:0051234 establishment of localization 9.863847e-17
GO:0051240 positive regulation of multicellular organismal process 1.033581e-16
GO:0006810 transport 1.130987e-16
GO:0007154 cell communication 2.223716e-16
GO:0002376 immune system process 2.232505e-16
GO:0048731 system development 4.043001e-16
GO:0055003 cardiac myofibril assembly 5.340179e-16
GO:0032101 regulation of response to external stimulus 3.864834e-15
GO:0043170 macromolecule metabolic process 4.144877e-15
GO:0007275 multicellular organismal development 5.637486e-15
GO:0051239 regulation of multicellular organismal process 7.445602e-15
GO:0032879 regulation of localization 1.109134e-14
GO:0007525 somatic muscle development 1.150811e-14
GO:0007596 blood coagulation 1.212150e-14
GO:0023052 signaling 1.623856e-14
GO:0048518 positive regulation of biological process 1.868397e-14
GO:0032940 secretion by cell 1.882794e-14
GO:0048769 sarcomerogenesis 2.010253e-14
GO:0007599 hemostasis 2.195467e-14
GO:0006955 immune response 2.537771e-14
GO:0051094 positive regulation of developmental process 2.603630e-14
GO:0042127 regulation of cell proliferation 2.775101e-14
GO:2000026 regulation of multicellular organismal development 4.693327e-14
GO:0003006 developmental process involved in reproduction 6.801638e-14
GO:0007076 mitotic chromosome condensation 7.497848e-14
GO:0032103 positive regulation of response to external stimulus 8.993297e-14
GO:0030240 skeletal muscle thin filament assembly 1.154332e-13
GO:0042493 response to drug 1.357903e-13
GO:0008152 metabolic process 2.149723e-13
GO:0018149 peptide cross-linking 2.343818e-13
GO:0072358 cardiovascular system development 4.022462e-13
GO:0022414 reproductive process 4.627991e-13
GO:0010033 response to organic substance 4.842128e-13
GO:0046903 secretion 5.028101e-13
GO:0044260 cellular macromolecule metabolic process 6.417094e-13
GO:0000003 reproduction 6.447467e-13
GO:0006928 cellular component movement 8.090050e-13
GO:0007166 cell surface receptor linked signaling pathway 8.351183e-13
GO:0044238 primary metabolic process 9.561937e-13
GO:0048583 regulation of response to stimulus 9.655470e-13
GO:0048522 positive regulation of cellular process 2.217614e-12
GO:0003008 system process 2.447932e-12
GO:0048468 cell development 2.476131e-12
GO:0071103 DNA conformation change 2.803638e-12
GO:0006464 protein modification process 3.023721e-12
GO:0019538 protein metabolic process 3.100228e-12
GO:0050878 regulation of body fluid levels 3.223126e-12
GO:0048523 negative regulation of cellular process 3.337439e-12
GO:0030261 chromosome condensation 3.538423e-12
GO:0048519 negative regulation of biological process 3.547689e-12
GO:0010035 response to inorganic substance 4.076871e-12
GO:0043067 regulation of programmed cell death 5.359353e-12
GO:0048520 positive regulation of behavior 6.707999e-12
GO:0045765 regulation of angiogenesis 7.188307e-12
GO:0010574 regulation of vascular endothelial growth factor production 7.343914e-12
GO:0042325 regulation of phosphorylation 8.030978e-12
GO:0042981 regulation of apoptosis 9.413985e-12
GO:0010941 regulation of cell death 9.966383e-12
GO:0051606 detection of stimulus 1.377174e-11
GO:0019220 regulation of phosphate metabolic process 2.052516e-11
GO:0060255 regulation of macromolecule metabolic process 2.062278e-11
GO:0055007 cardiac muscle cell differentiation 2.129579e-11
GO:0019222 regulation of metabolic process 2.148305e-11
GO:0009893 positive regulation of metabolic process 2.883221e-11
GO:0043412 macromolecule modification 3.077724e-11
GO:0050795 regulation of behavior 3.134533e-11
GO:0045595 regulation of cell differentiation 3.616695e-11
GO:0001819 positive regulation of cytokine production 4.869476e-11
GO:0051093 negative regulation of developmental process 4.977785e-11
GO:0051641 cellular localization 5.419325e-11
GO:0043069 negative regulation of programmed cell death 5.482331e-11
GO:0048646 anatomical structure formation involved in morphogenesis 6.377771e-11
GO:0048869 cellular developmental process 6.480324e-11
GO:0051649 establishment of localization in cell 7.839392e-11
GO:0030241 skeletal muscle myosin thick filament assembly 9.994243e-11
GO:0050776 regulation of immune response 1.122209e-10
GO:0043066 negative regulation of apoptosis 1.196909e-10
GO:0050727 regulation of inflammatory response 1.217144e-10
GO:0031323 regulation of cellular metabolic process 1.357819e-10
GO:0048608 reproductive structure development 1.371689e-10
GO:0030049 muscle filament sliding 1.427338e-10
GO:0060548 negative regulation of cell death 1.452175e-10
GO:0000819 sister chromatid segregation 2.095297e-10
GO:0031394 positive regulation of prostaglandin biosynthetic process 2.211368e-10
GO:0007049 cell cycle 2.391950e-10
GO:0010604 positive regulation of macromolecule metabolic process 2.415625e-10
GO:0040012 regulation of locomotion 2.668930e-10
GO:0032496 response to lipopolysaccharide 2.856431e-10
GO:0090304 nucleic acid metabolic process 2.872949e-10
GO:0070252 actin-mediated cell contraction 2.910504e-10
GO:0006887 exocytosis 2.985787e-10
GO:0044267 cellular protein metabolic process 3.008047e-10
GO:0048739 cardiac muscle fiber development 3.659496e-10
GO:0030154 cell differentiation 3.710457e-10
GO:0006323 DNA packaging 3.952663e-10
GO:0030334 regulation of cell migration 3.984424e-10
GO:0060324 face development 4.176197e-10
GO:0007155 cell adhesion 4.966382e-10
GO:0032268 regulation of cellular protein metabolic process 5.282211e-10
GO:0002683 negative regulation of immune system process 5.605155e-10
GO:0045597 positive regulation of cell differentiation 5.746541e-10
GO:0048585 negative regulation of response to stimulus 5.918534e-10
GO:0000070 mitotic sister chromatid segregation 6.031728e-10
GO:0044237 cellular metabolic process 6.246785e-10
GO:0051592 response to calcium ion 6.875683e-10
GO:0051049 regulation of transport 7.099982e-10
GO:0016192 vesicle-mediated transport 7.977692e-10
GO:0040017 positive regulation of locomotion 9.214063e-10
GO:0045214 sarcomere organization 1.169370e-9
GO:0045087 innate immune response 1.226017e-9
GO:0048609 multicellular organismal reproductive process 1.278402e-9
GO:0002237 response to molecule of bacterial origin 1.291972e-9
GO:0035051 cardiac cell differentiation 1.391509e-9
GO:0014866 skeletal myofibril assembly 1.496751e-9
GO:0033036 macromolecule localization 1.709313e-9
GO:0030728 ovulation 1.713629e-9
GO:0051050 positive regulation of transport 1.870047e-9
GO:0050864 regulation of B cell activation 2.216380e-9
GO:0043032 positive regulation of macrophage activation 2.273904e-9
GO:2000145 regulation of cell motility 2.363685e-9
GO:0007067 mitosis 2.472504e-9
GO:0023057 negative regulation of signaling 2.630693e-9
GO:0022402 cell cycle process 2.647679e-9
GO:0030048 actin filament-based movement 2.743106e-9
GO:0048644 muscle organ morphogenesis 2.926181e-9
GO:0007186 G-protein coupled receptor protein signaling pathway 2.947852e-9
GO:0010648 negative regulation of cell communication 2.981302e-9
GO:0016525 negative regulation of angiogenesis 3.066529e-9
GO:0001932 regulation of protein phosphorylation 3.151895e-9
GO:0032735 positive regulation of interleukin-12 production 3.341665e-9
GO:0030239 myofibril assembly 3.695187e-9
GO:0008585 female gonad development 3.752156e-9
GO:0043615 astrocyte cell migration 3.940346e-9
GO:0000087 M phase of mitotic cell cycle 3.963731e-9
GO:0050869 negative regulation of B cell activation 4.249829e-9
GO:0002690 positive regulation of leukocyte chemotaxis 4.987932e-9
GO:0008406 gonad development 5.069303e-9
GO:0031099 regeneration 5.134554e-9
GO:0050921 positive regulation of chemotaxis 5.261837e-9
GO:0050865 regulation of cell activation 5.284469e-9
GO:0060322 head development 5.412673e-9
GO:0048285 organelle fission 5.723050e-9
GO:0046660 female sex differentiation 6.733744e-9
GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process 6.771477e-9
GO:0051409 response to nitrosative stress 7.082919e-9
GO:0007517 muscle organ development 7.756516e-9
GO:0031100 organ regeneration 7.852779e-9
GO:0002688 regulation of leukocyte chemotaxis 8.505618e-9
GO:0045723 positive regulation of fatty acid biosynthetic process 8.813888e-9
GO:0050920 regulation of chemotaxis 9.021996e-9
GO:0046545 development of primary female sexual characteristics 9.213053e-9
GO:0040008 regulation of growth 9.376450e-9
GO:0051769 regulation of nitric-oxide synthase biosynthetic process 9.534823e-9
GO:0008285 negative regulation of cell proliferation 1.103224e-8
GO:0048511 rhythmic process 1.115439e-8
GO:0051704 multi-organism process 1.116464e-8
GO:0010468 regulation of gene expression 1.128812e-8
GO:0055001 muscle cell development 1.153693e-8
GO:0031032 actomyosin structure organization 1.210557e-8
GO:0007507 heart development 1.229838e-8
GO:0032026 response to magnesium ion 1.570782e-8
GO:0051270 regulation of cellular component movement 1.583744e-8
GO:0010758 regulation of macrophage chemotaxis 1.619844e-8
GO:0021854 hypothalamus development 1.702469e-8
GO:0090265 positive regulation of immune complex clearance by monocytes and macrophages 1.830767e-8
GO:0007548 sex differentiation 1.926952e-8
GO:0050778 positive regulation of immune response 2.329641e-8
GO:0051246 regulation of protein metabolic process 2.354371e-8
GO:0048771 tissue remodeling 2.425650e-8
GO:0009628 response to abiotic stimulus 2.565893e-8
GO:0002673 regulation of acute inflammatory response 2.661596e-8
GO:0002684 positive regulation of immune system process 2.707553e-8
GO:0002694 regulation of leukocyte activation 2.830912e-8
GO:0030888 regulation of B cell proliferation 2.936575e-8
GO:0042180 cellular ketone metabolic process 2.951212e-8
GO:0001817 regulation of cytokine production 3.106840e-8
GO:0051707 response to other organism 3.144463e-8
GO:0002687 positive regulation of leukocyte migration 3.321318e-8
GO:0045137 development of primary sexual characteristics 3.463006e-8
GO:0009889 regulation of biosynthetic process 3.511991e-8
GO:0048584 positive regulation of response to stimulus 3.593225e-8
GO:0003012 muscle system process 3.932031e-8
GO:0000255 allantoin metabolic process 4.143049e-8
GO:0045346 regulation of MHC class II biosynthetic process 4.644054e-8
GO:0080090 regulation of primary metabolic process 4.730703e-8
GO:0006807 nitrogen compound metabolic process 5.086979e-8
GO:0055008 cardiac muscle tissue morphogenesis 5.807326e-8
GO:0060452 positive regulation of cardiac muscle contraction 5.944097e-8
GO:0032317 regulation of Rap GTPase activity 6.327876e-8
GO:0009306 protein secretion 6.773814e-8
GO:0042554 superoxide anion generation 6.782686e-8
GO:0071310 cellular response to organic substance 6.808734e-8
GO:0030335 positive regulation of cell migration 6.848908e-8
GO:0009968 negative regulation of signal transduction 7.986079e-8
GO:0002685 regulation of leukocyte migration 8.482639e-8
GO:0071622 regulation of granulocyte chemotaxis 8.750593e-8
GO:0045766 positive regulation of angiogenesis 9.062970e-8
GO:2000147 positive regulation of cell motility 9.091285e-8
GO:0031325 positive regulation of cellular metabolic process 9.459361e-8
GO:2000379 positive regulation of reactive oxygen species metabolic process 9.653906e-8
GO:0050729 positive regulation of inflammatory response 9.674567e-8
GO:0030595 leukocyte chemotaxis 9.699882e-8
GO:0070887 cellular response to chemical stimulus 1.075112e-7
GO:0000278 mitotic cell cycle 1.107201e-7
GO:0048738 cardiac muscle tissue development 1.146737e-7
GO:0060415 muscle tissue morphogenesis 1.158908e-7
GO:0009617 response to bacterium 1.179737e-7
GO:0008284 positive regulation of cell proliferation 1.188129e-7
GO:0010038 response to metal ion 1.199340e-7
GO:2001021 negative regulation of response to DNA damage stimulus 1.210945e-7
GO:0048066 developmental pigmentation 1.218163e-7
GO:0022602 ovulation cycle process 1.298034e-7
GO:0035684 helper T cell extravasation 1.336778e-7
GO:0009581 detection of external stimulus 1.363257e-7
GO:0032728 positive regulation of interferon-beta production 1.425924e-7
GO:0010556 regulation of macromolecule biosynthetic process 1.448208e-7
GO:0031399 regulation of protein modification process 1.592708e-7
GO:0009891 positive regulation of biosynthetic process 1.662074e-7
GO:0009653 anatomical structure morphogenesis 1.843077e-7
GO:0042535 positive regulation of tumor necrosis factor biosynthetic process 1.898083e-7
GO:0006911 phagocytosis, engulfment 1.950753e-7
GO:0031349 positive regulation of defense response 1.992474e-7
GO:0071222 cellular response to lipopolysaccharide 2.007713e-7
GO:0034641 cellular nitrogen compound metabolic process 2.125507e-7
GO:0006259 DNA metabolic process 2.165520e-7
GO:0055098 response to low-density lipoprotein particle stimulus 2.213328e-7
GO:0050867 positive regulation of cell activation 2.313502e-7
GO:0010575 positive regulation vascular endothelial growth factor production 2.338313e-7
GO:0042698 ovulation cycle 2.369269e-7
GO:0033554 cellular response to stress 2.414513e-7
GO:0009607 response to biotic stimulus 2.438226e-7
GO:0019752 carboxylic acid metabolic process 2.480491e-7
GO:0060740 prostate gland epithelium morphogenesis 2.543741e-7
GO:0010759 positive regulation of macrophage chemotaxis 2.700383e-7
GO:0048870 cell motility 2.714237e-7
GO:0034059 response to anoxia 3.021332e-7
GO:0000165 MAPKKK cascade 3.112645e-7
GO:0001655 urogenital system development 3.175010e-7
GO:0061008 hepaticobiliary system development 3.222474e-7
GO:0055002 striated muscle cell development 3.267339e-7
GO:0032479 regulation of type I interferon production 3.305192e-7
GO:0045091 regulation of retroviral genome replication 3.321432e-7
GO:0048729 tissue morphogenesis 3.375974e-7
GO:0051272 positive regulation of cellular component movement 3.736308e-7
GO:0071219 cellular response to molecule of bacterial origin 3.985108e-7
GO:0006082 organic acid metabolic process 4.246888e-7
GO:0045740 positive regulation of DNA replication 4.348589e-7
GO:0070663 regulation of leukocyte proliferation 4.363052e-7
GO:0031326 regulation of cellular biosynthetic process 4.583259e-7
GO:0060537 muscle tissue development 4.621939e-7
GO:0032854 positive regulation of Rap GTPase activity 4.857530e-7
GO:0071840 cellular component organization or biogenesis 5.138102e-7
GO:0010955 negative regulation of protein processing 5.145654e-7
GO:0010754 negative regulation of cGMP-mediated signaling 5.184666e-7
GO:0043652 engulfment of apoptotic cell 5.184666e-7
GO:0010751 negative regulation of nitric oxide mediated signal transduction 5.184666e-7
GO:0002605 negative regulation of dendritic cell antigen processing and presentation 5.184666e-7
GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 5.184666e-7
GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator 5.186198e-7
GO:0010608 posttranscriptional regulation of gene expression 5.263140e-7
GO:0006916 anti-apoptosis 5.283838e-7
GO:0032642 regulation of chemokine production 5.456031e-7
GO:0050953 sensory perception of light stimulus 5.584634e-7
GO:0060512 prostate gland morphogenesis 5.596600e-7
GO:0001889 liver development 5.884804e-7
GO:0016477 cell migration 6.417797e-7
GO:0071216 cellular response to biotic stimulus 6.456350e-7
GO:0042327 positive regulation of phosphorylation 6.602968e-7
GO:0008104 protein localization 6.667134e-7
GO:0070668 positive regulation of mast cell proliferation 6.783079e-7
GO:0008206 bile acid metabolic process 6.883708e-7
GO:0034605 cellular response to heat 7.033615e-7
GO:0045859 regulation of protein kinase activity 7.091053e-7
GO:0002674 negative regulation of acute inflammatory response 7.115912e-7
GO:0071675 regulation of mononuclear cell migration 7.189716e-7
GO:0045596 negative regulation of cell differentiation 7.789502e-7
GO:0032655 regulation of interleukin-12 production 7.865668e-7
GO:0050931 pigment cell differentiation 7.937881e-7
GO:0040036 regulation of fibroblast growth factor receptor signaling pathway 8.073263e-7
GO:0061061 muscle structure development 8.215070e-7
GO:0007600 sensory perception 8.629864e-7
GO:0010165 response to X-ray 9.479143e-7
GO:0014823 response to activity 9.616782e-7
GO:2000112 regulation of cellular macromolecule biosynthetic process 1.063888e-6
GO:0034694 response to prostaglandin stimulus 1.065754e-6
GO:0007601 visual perception 1.077834e-6
GO:0032481 positive regulation of type I interferon production 1.089703e-6
GO:0042035 regulation of cytokine biosynthetic process 1.101898e-6
GO:0002520 immune system development 1.139193e-6
GO:0002682 regulation of immune system process 1.203898e-6
GO:0050900 leukocyte migration 1.208627e-6
GO:0030889 negative regulation of B cell proliferation 1.220115e-6
GO:0080134 regulation of response to stress 1.235588e-6
GO:0006936 muscle contraction 1.235797e-6
GO:0002696 positive regulation of leukocyte activation 1.271734e-6
GO:0023051 regulation of signaling 1.308560e-6
GO:0010646 regulation of cell communication 1.312773e-6
GO:0043405 regulation of MAP kinase activity 1.330431e-6
GO:0016043 cellular component organization 1.359762e-6
GO:0006941 striated muscle contraction 1.391524e-6
GO:0014706 striated muscle tissue development 1.412653e-6
GO:0060137 maternal process involved in parturition 1.418583e-6
GO:0070365 hepatocyte differentiation 1.450677e-6
GO:0010757 negative regulation of plasminogen activation 1.458853e-6
GO:0042663 regulation of endodermal cell fate specification 1.495010e-6
GO:0008347 glial cell migration 1.499257e-6
GO:0015031 protein transport 1.524721e-6
GO:0030029 actin filament-based process 1.531943e-6
GO:0034097 response to cytokine stimulus 1.582187e-6
GO:0006629 lipid metabolic process 1.593094e-6
GO:0043536 positive regulation of blood vessel endothelial cell migration 1.641685e-6
GO:0008584 male gonad development 1.692812e-6
GO:0042438 melanin biosynthetic process 1.725345e-6
GO:0045937 positive regulation of phosphate metabolic process 1.789254e-6
GO:0090066 regulation of anatomical structure size 1.974678e-6
GO:0043030 regulation of macrophage activation 1.982587e-6
GO:0002246 wound healing involved in inflammatory response 2.007098e-6
GO:0045347 negative regulation of MHC class II biosynthetic process 2.018107e-6
GO:0090362 positive regulation of platelet-derived growth factor production 2.018970e-6
GO:0090336 positive regulation of brown fat cell differentiation 2.018970e-6
GO:0090271 positive regulation of fibroblast growth factor production 2.018970e-6
GO:0071985 multivesicular body sorting pathway 2.091692e-6
GO:0043549 regulation of kinase activity 2.113091e-6
GO:0031644 regulation of neurological system process 2.118217e-6
GO:0006930 substrate-dependent cell migration, cell extension 2.182561e-6
GO:0007292 female gamete generation 2.190551e-6
GO:0008207 C21-steroid hormone metabolic process 2.223166e-6
GO:0010557 positive regulation of macromolecule biosynthetic process 2.241464e-6
GO:0012501 programmed cell death 2.398742e-6
GO:0019428 allantoin biosynthetic process 2.398783e-6
GO:0019915 lipid storage 2.416791e-6
GO:0006796 phosphate-containing compound metabolic process 2.677096e-6
GO:0022403 cell cycle phase 2.683790e-6
GO:0010594 regulation of endothelial cell migration 2.828720e-6
GO:0006508 proteolysis 2.851664e-6
GO:0010942 positive regulation of cell death 2.889632e-6
GO:0048638 regulation of developmental growth 2.902873e-6
GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator 2.970150e-6
GO:0009966 regulation of signal transduction 3.019084e-6
GO:0043068 positive regulation of programmed cell death 3.112666e-6
GO:0050906 detection of stimulus involved in sensory perception 3.157824e-6
GO:0071634 regulation of transforming growth factor beta production 3.207387e-6
GO:0045076 regulation of interleukin-2 biosynthetic process 3.300032e-6
GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway 3.308369e-6
GO:0001937 negative regulation of endothelial cell proliferation 3.395234e-6
GO:0030001 metal ion transport 3.431242e-6
GO:0045069 regulation of viral genome replication 3.435130e-6
GO:0031646 positive regulation of neurological system process 3.496240e-6
GO:0032760 positive regulation of tumor necrosis factor production 3.546480e-6
GO:0009058 biosynthetic process 3.548428e-6
GO:0007276 gamete generation 3.587828e-6
GO:0042264 peptidyl-aspartic acid hydroxylation 3.598621e-6
GO:0051338 regulation of transferase activity 3.812799e-6
GO:0032680 regulation of tumor necrosis factor production 3.875984e-6
GO:0019725 cellular homeostasis 3.877422e-6
GO:0007059 chromosome segregation 3.980784e-6
GO:0042100 B cell proliferation 4.043448e-6
GO:0009266 response to temperature stimulus 4.151457e-6
GO:0009408 response to heat 4.258264e-6
GO:0043603 cellular amide metabolic process 4.261249e-6
GO:0031328 positive regulation of cellular biosynthetic process 4.360737e-6
GO:0043065 positive regulation of apoptosis 4.456720e-6
GO:0071636 positive regulation of transforming growth factor beta production 4.476351e-6
GO:0032989 cellular component morphogenesis 4.590682e-6
GO:0030518 steroid hormone receptor signaling pathway 4.612698e-6
GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway 4.791653e-6
GO:0051971 positive regulation of transmission of nerve impulse 4.838694e-6
GO:0051276 chromosome organization 4.862822e-6
GO:0048747 muscle fiber development 4.922787e-6
GO:0006811 ion transport 4.990712e-6
GO:0071726 cellular response to diacyl bacterial lipopeptide 4.992680e-6
GO:0042496 detection of diacyl bacterial lipopeptide 4.992680e-6
GO:0030098 lymphocyte differentiation 5.057902e-6
GO:0061039 ovum-producing ovary development 5.058400e-6
GO:0090270 regulation of fibroblast growth factor production 5.078017e-6
GO:0048534 hemopoietic or lymphoid organ development 5.239775e-6
GO:0032227 negative regulation of synaptic transmission, dopaminergic 5.275295e-6
GO:0032648 regulation of interferon-beta production 5.505248e-6
GO:0022603 regulation of anatomical structure morphogenesis 5.681097e-6
GO:0046677 response to antibiotic 5.819520e-6
GO:0001936 regulation of endothelial cell proliferation 5.895749e-6
GO:0002544 chronic inflammatory response 5.988971e-6
GO:0045921 positive regulation of exocytosis 6.116304e-6
GO:0030832 regulation of actin filament length 6.189476e-6
GO:0051171 regulation of nitrogen compound metabolic process 6.280608e-6
GO:0030318 melanocyte differentiation 6.283666e-6
GO:0042448 progesterone metabolic process 6.293731e-6
GO:0071223 cellular response to lipoteichoic acid 6.502197e-6
GO:0010755 regulation of plasminogen activation 6.515579e-6
GO:0010595 positive regulation of endothelial cell migration 6.583490e-6
GO:0008283 cell proliferation 6.684802e-6
GO:0016337 cell-cell adhesion 6.998358e-6
GO:0006139 nucleobase-containing compound metabolic process 7.000775e-6
GO:0030097 hemopoiesis 7.073146e-6
GO:0032570 response to progesterone stimulus 7.082463e-6
GO:0034754 cellular hormone metabolic process 7.352223e-6
GO:0032741 positive regulation of interleukin-18 production 7.461005e-6
GO:0007530 sex determination 7.527288e-6
GO:0009605 response to external stimulus 7.629093e-6
GO:0010212 response to ionizing radiation 7.744886e-6
GO:0006275 regulation of DNA replication 7.885738e-6
GO:0019219 regulation of nucleobase-containing compound metabolic process 7.918079e-6
GO:0071345 cellular response to cytokine stimulus 7.936269e-6
GO:0043535 regulation of blood vessel endothelial cell migration 8.194840e-6
GO:0048863 stem cell differentiation 8.272535e-6
GO:0051895 negative regulation of focal adhesion assembly 8.288633e-6
GO:0001547 antral ovarian follicle growth 8.346424e-6
GO:0006417 regulation of translation 8.506240e-6
GO:0015721 bile acid and bile salt transport 8.582459e-6
GO:0016339 calcium-dependent cell-cell adhesion 8.815690e-6
GO:0008202 steroid metabolic process 9.246317e-6
GO:0048545 response to steroid hormone stimulus 9.613854e-6
GO:0043473 pigmentation 9.798580e-6
GO:0009593 detection of chemical stimulus 9.935805e-6
GO:0046219 indolalkylamine biosynthetic process 1.008007e-5
GO:0045086 positive regulation of interleukin-2 biosynthetic process 1.008642e-5
GO:0048240 sperm capacitation 1.010714e-5
GO:0006582 melanin metabolic process 1.017252e-5
GO:0042534 regulation of tumor necrosis factor biosynthetic process 1.025200e-5
GO:0055082 cellular chemical homeostasis 1.030816e-5
GO:0045989 positive regulation of striated muscle contraction 1.041671e-5
GO:0051047 positive regulation of secretion 1.090223e-5
GO:0019953 sexual reproduction 1.090443e-5
GO:0010715 regulation of extracellular matrix disassembly 1.152734e-5
GO:0030259 lipid glycosylation 1.188925e-5
GO:0007281 germ cell development 1.192062e-5
GO:0002312 B cell activation involved in immune response 1.231134e-5
GO:0006338 chromatin remodeling 1.268018e-5
GO:0000279 M phase 1.297900e-5
GO:0007622 rhythmic behavior 1.316292e-5
GO:0072678 T cell migration 1.318215e-5
GO:0031645 negative regulation of neurological system process 1.351895e-5
GO:0051247 positive regulation of protein metabolic process 1.372205e-5
GO:0034695 response to prostaglandin E stimulus 1.377293e-5
GO:0044249 cellular biosynthetic process 1.391581e-5
GO:0070374 positive regulation of ERK1 and ERK2 cascade 1.402266e-5
GO:0060284 regulation of cell development 1.450894e-5
GO:0051642 centrosome localization 1.454850e-5
GO:0030186 melatonin metabolic process 1.475681e-5
GO:0070779 D-aspartate import 1.494848e-5
GO:0001525 angiogenesis 1.554875e-5
GO:0032722 positive regulation of chemokine production 1.590658e-5
GO:0052548 regulation of endopeptidase activity 1.640301e-5
GO:0032102 negative regulation of response to external stimulus 1.646167e-5
GO:0002757 immune response-activating signal transduction 1.676257e-5
GO:0045909 positive regulation of vasodilation 1.687545e-5
GO:0032273 positive regulation of protein polymerization 1.706472e-5
GO:0050871 positive regulation of B cell activation 1.711119e-5
GO:0070482 response to oxygen levels 1.716474e-5
GO:0048245 eosinophil chemotaxis 1.730383e-5
GO:0006542 glutamine biosynthetic process 1.733886e-5
GO:0070098 chemokine-mediated signaling pathway 1.739190e-5
GO:0001816 cytokine production 1.749576e-5
GO:0051969 regulation of transmission of nerve impulse 1.841388e-5
GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway 1.850429e-5
GO:0060442 branching involved in prostate gland morphogenesis 1.893955e-5
GO:0045184 establishment of protein localization 1.909957e-5
GO:0030036 actin cytoskeleton organization 1.919698e-5
GO:0033026 negative regulation of mast cell apoptosis 1.923726e-5
GO:0045598 regulation of fat cell differentiation 1.942401e-5
GO:0030730 sequestering of triglyceride 2.055972e-5
GO:0035583 negative regulation of transforming growth factor beta receptor signaling pathway by extracellular sequestering of TGFbeta 2.072830e-5
GO:0046622 positive regulation of organ growth 2.073537e-5
GO:0050670 regulation of lymphocyte proliferation 2.084935e-5
GO:2000370 positive regulation of clathrin-mediated endocytosis 2.133842e-5
GO:0022605 oogenesis stage 2.140216e-5
GO:0032409 regulation of transporter activity 2.149420e-5
GO:0015810 aspartate transport 2.163101e-5
GO:0002764 immune response-regulating signaling pathway 2.207573e-5
GO:0000096 sulfur amino acid metabolic process 2.219786e-5
GO:0030850 prostate gland development 2.258812e-5
GO:0045933 positive regulation of muscle contraction 2.261845e-5
GO:0051252 regulation of RNA metabolic process 2.332053e-5
GO:0051970 negative regulation of transmission of nerve impulse 2.540356e-5
GO:0010628 positive regulation of gene expression 2.548832e-5


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0021854 hypothalamus development 9.240589e-10
GO:0022408 negative regulation of cell-cell adhesion 1.138578e-8
GO:0040017 positive regulation of locomotion 8.351531e-8
GO:0043056 forward locomotion 1.117029e-7
GO:0033058 directional locomotion 1.912454e-7
GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response 2.428167e-7
GO:0046640 regulation of alpha-beta T cell proliferation 3.225887e-7
GO:0006278 RNA-dependent DNA replication 3.467510e-7
GO:0006613 cotranslational protein targeting to membrane 3.779829e-7
GO:0060009 Sertoli cell development 4.385844e-7
GO:0060907 positive regulation of macrophage cytokine production 5.071554e-7
GO:0060008 Sertoli cell differentiation 8.403804e-7
GO:0010935 regulation of macrophage cytokine production 8.461705e-7
GO:0007162 negative regulation of cell adhesion 1.099598e-6
GO:0006614 SRP-dependent cotranslational protein targeting to membrane 1.307666e-6
GO:0009743 response to carbohydrate stimulus 2.085968e-6
GO:0046642 negative regulation of alpha-beta T cell proliferation 2.106090e-6
GO:0051272 positive regulation of cellular component movement 2.254064e-6
GO:2000147 positive regulation of cell motility 2.528090e-6
GO:0071223 cellular response to lipoteichoic acid 2.534258e-6
GO:0000187 activation of MAPK activity 2.573743e-6
GO:0043406 positive regulation of MAP kinase activity 2.719179e-6
GO:0032735 positive regulation of interleukin-12 production 3.593206e-6
GO:0032653 regulation of interleukin-10 production 4.143396e-6
GO:0006811 ion transport 4.351153e-6
GO:0071956 cellular component maintenance at cellular level 4.881105e-6
GO:0006756 AMP phosphorylation 5.587701e-6
GO:0046709 IDP catabolic process 6.775703e-6
GO:0046032 ADP catabolic process 6.775703e-6
GO:0045338 farnesyl diphosphate metabolic process 6.927811e-6
GO:0040012 regulation of locomotion 9.103205e-6
GO:0021700 developmental maturation 9.652829e-6
GO:0021604 cranial nerve structural organization 1.092406e-5
GO:0002861 regulation of inflammatory response to antigenic stimulus 1.103425e-5
GO:0048240 sperm capacitation 1.111900e-5
GO:0070663 regulation of leukocyte proliferation 1.116119e-5
GO:0032944 regulation of mononuclear cell proliferation 1.248452e-5
GO:0050670 regulation of lymphocyte proliferation 1.323242e-5
GO:0006629 lipid metabolic process 1.424132e-5
GO:0002891 positive regulation of immunoglobulin mediated immune response 1.427968e-5
GO:0002922 positive regulation of humoral immune response 1.491287e-5
GO:0051297 centrosome organization 1.589970e-5
GO:0045060 negative thymic T cell selection 1.589970e-5
GO:0045061 thymic T cell selection 1.757217e-5
GO:0009617 response to bacterium 1.830124e-5
GO:0030335 positive regulation of cell migration 1.845103e-5
GO:0051346 negative regulation of hydrolase activity 1.858695e-5
GO:0010466 negative regulation of peptidase activity 2.041112e-5
GO:0022610 biological adhesion 2.370412e-5
GO:0015672 monovalent inorganic cation transport 2.541226e-5
GO:0042753 positive regulation of circadian rhythm 2.715480e-5
GO:0042130 negative regulation of T cell proliferation 2.728993e-5
GO:0050777 negative regulation of immune response 2.859397e-5
GO:0002720 positive regulation of cytokine production involved in immune response 2.882155e-5
GO:0002683 negative regulation of immune system process 3.005406e-5
GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter 3.214722e-5
GO:0034126 positive regulation of MyD88-dependent toll-like receptor signaling pathway 3.258648e-5
GO:0021553 olfactory nerve development 3.403116e-5
GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine 3.478227e-5
GO:0001810 regulation of type I hypersensitivity 3.478227e-5
GO:0060324 face development 3.488663e-5
GO:0090074 negative regulation of protein homodimerization activity 3.567433e-5
GO:0021629 olfactory nerve structural organization 3.567433e-5
GO:0022407 regulation of cell-cell adhesion 3.581308e-5
GO:0060307 regulation of ventricular cardiomyocyte membrane repolarization 3.930081e-5
GO:0060299 negative regulation of sarcomere organization 3.930081e-5
GO:0006812 cation transport 4.099421e-5
GO:0046940 nucleoside monophosphate phosphorylation 4.125255e-5
GO:0043954 cellular component maintenance 4.223089e-5
GO:0050672 negative regulation of lymphocyte proliferation 4.281221e-5
GO:0007155 cell adhesion 4.900134e-5
GO:0070314 G1 to G0 transition 5.077137e-5
GO:0060271 cilium morphogenesis 5.210564e-5
GO:0032760 positive regulation of tumor necrosis factor production 5.421595e-5
GO:0002761 regulation of myeloid leukocyte differentiation 5.528265e-5
GO:0043383 negative T cell selection 5.656086e-5
GO:0051915 induction of synaptic plasticity by chemical substance 5.862093e-5
GO:0002883 regulation of hypersensitivity 6.051916e-5
GO:0043486 histone exchange 6.094469e-5
GO:0071805 potassium ion transmembrane transport 6.451833e-5
GO:0007263 nitric oxide mediated signal transduction 6.518670e-5
GO:0046185 aldehyde catabolic process 6.607828e-5
GO:0051270 regulation of cellular component movement 7.092248e-5
GO:0051707 response to other organism 7.148354e-5
GO:0070664 negative regulation of leukocyte proliferation 7.152886e-5
GO:0002606 positive regulation of dendritic cell antigen processing and presentation 7.269860e-5
GO:0021602 cranial nerve morphogenesis 7.412389e-5
GO:0032273 positive regulation of protein polymerization 7.835684e-5
GO:0021631 optic nerve morphogenesis 7.999663e-5
GO:0031023 microtubule organizing center organization 8.409499e-5
GO:0072108 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 8.604691e-5
GO:0070206 protein trimerization 8.615295e-5
GO:0032655 regulation of interleukin-12 production 8.624420e-5
GO:0060322 head development 9.011451e-5
GO:0051704 multi-organism process 9.031909e-5
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I 9.908372e-5
GO:0042129 regulation of T cell proliferation 1.033790e-4
GO:0071404 cellular response to low-density lipoprotein particle stimulus 1.057481e-4
GO:0045059 positive thymic T cell selection 1.076861e-4
GO:0032755 positive regulation of interleukin-6 production 1.089315e-4
GO:0006547 histidine metabolic process 1.215183e-4
GO:0071731 response to nitric oxide 1.277894e-4
GO:0009636 response to toxin 1.309688e-4
GO:0051101 regulation of DNA binding 1.319897e-4
GO:0044262 cellular carbohydrate metabolic process 1.353998e-4
GO:0043519 regulation of myosin II filament organization 1.357847e-4
GO:0048630 skeletal muscle tissue growth 1.386507e-4
GO:0051817 modification of morphology or physiology of other organism involved in symbiotic interaction 1.400464e-4
GO:0001819 positive regulation of cytokine production 1.434614e-4
GO:0002604 regulation of dendritic cell antigen processing and presentation 1.478636e-4
GO:0015724 formate transport 1.492833e-4
GO:0006548 histidine catabolic process 1.496068e-4
GO:2000145 regulation of cell motility 1.500808e-4
GO:0060364 frontal suture morphogenesis 1.541743e-4
GO:0032656 regulation of interleukin-13 production 1.544949e-4
GO:0033993 response to lipid 1.774324e-4
GO:0048793 pronephros development 1.803640e-4
GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 1.823508e-4
GO:0070430 positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 1.823508e-4
GO:0045362 positive regulation of interleukin-1 biosynthetic process 1.823508e-4
GO:0032707 negative regulation of interleukin-23 production 1.823508e-4
GO:0071402 cellular response to lipoprotein particle stimulus 1.870481e-4
GO:0006952 defense response 1.952139e-4
GO:0008610 lipid biosynthetic process 1.952839e-4
GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway 1.955578e-4
GO:0009408 response to heat 1.993508e-4
GO:0045217 cell-cell junction maintenance 1.997849e-4
GO:0055096 low-density lipoprotein particle mediated signaling 2.024230e-4
GO:0020028 hemoglobin import 2.048929e-4
GO:0046634 regulation of alpha-beta T cell activation 2.078184e-4
GO:0050868 negative regulation of T cell activation 2.126818e-4
GO:0034097 response to cytokine stimulus 2.146077e-4
GO:0008299 isoprenoid biosynthetic process 2.155463e-4
GO:0060042 retina morphogenesis in camera-type eye 2.194798e-4
GO:0009181 purine ribonucleoside diphosphate catabolic process 2.260861e-4
GO:0097035 regulation of membrane lipid distribution 2.467418e-4
GO:0009607 response to biotic stimulus 2.475867e-4
GO:0050770 regulation of axonogenesis 2.497927e-4
GO:0072384 organelle transport along microtubule 2.529464e-4
GO:0032570 response to progesterone stimulus 2.640984e-4
GO:0055114 oxidation-reduction process 2.659005e-4
GO:0033189 response to vitamin A 2.695478e-4
GO:0006950 response to stress 2.707119e-4
GO:0055085 transmembrane transport 2.821726e-4
GO:0007243 intracellular protein kinase cascade 2.853515e-4
GO:0045843 negative regulation of striated muscle tissue development 2.861309e-4
GO:0047497 mitochondrion transport along microtubule 2.908121e-4
GO:0007184 SMAD protein import into nucleus 2.908121e-4
GO:0007257 activation of JUN kinase activity 3.044788e-4
GO:0031638 zymogen activation 3.045288e-4
GO:0016090 prenol metabolic process 3.275032e-4
GO:0006820 anion transport 3.315608e-4
GO:0032534 regulation of microvillus assembly 3.353124e-4
GO:0005975 carbohydrate metabolic process 3.374031e-4
GO:0051531 NFAT protein import into nucleus 3.397746e-4
GO:0034605 cellular response to heat 3.512101e-4
GO:0010951 negative regulation of endopeptidase activity 3.564823e-4
GO:0042775 mitochondrial ATP synthesis coupled electron transport 3.611250e-4
GO:0051795 positive regulation of catagen 3.611889e-4
GO:0042628 mating plug formation 3.611889e-4
GO:0051654 establishment of mitochondrion localization 3.746033e-4
GO:0015695 organic cation transport 3.871542e-4
GO:0006882 cellular zinc ion homeostasis 3.992728e-4
GO:0050730 regulation of peptidyl-tyrosine phosphorylation 4.106120e-4
GO:0010638 positive regulation of organelle organization 4.209242e-4
GO:0015701 bicarbonate transport 4.298520e-4
GO:0060100 positive regulation of phagocytosis, engulfment 4.345674e-4
GO:0061153 trachea gland development 4.498991e-4
GO:0007217 tachykinin receptor signaling pathway 4.498991e-4
GO:0032733 positive regulation of interleukin-10 production 4.500269e-4
GO:0071902 positive regulation of protein serine/threonine kinase activity 4.521781e-4
GO:0007584 response to nutrient 4.613689e-4
GO:0002864 regulation of acute inflammatory response to antigenic stimulus 4.670165e-4
GO:0006054 N-acetylneuraminate metabolic process 4.820674e-4
GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin 4.883122e-4
GO:0050896 response to stimulus 4.889190e-4
GO:0043967 histone H4 acetylation 5.045606e-4
GO:0048818 positive regulation of hair follicle maturation 5.063632e-4
GO:0009611 response to wounding 5.156292e-4
GO:0046636 negative regulation of alpha-beta T cell activation 5.326978e-4
GO:0021965 spinal cord ventral commissure morphogenesis 5.401978e-4
GO:0050771 negative regulation of axonogenesis 5.423777e-4
GO:0032673 regulation of interleukin-4 production 5.439431e-4
GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin 5.442156e-4
GO:0071732 cellular response to nitric oxide 5.650427e-4
GO:0033630 positive regulation of cell adhesion mediated by integrin 5.650427e-4
GO:0008272 sulfate transport 5.650427e-4
GO:0034509 centromeric core chromatin assembly 5.665454e-4
GO:0034080 CenH3-containing nucleosome assembly at centromere 5.665454e-4
GO:0033634 positive regulation of cell-cell adhesion mediated by integrin 5.691142e-4
GO:0006463 steroid hormone receptor complex assembly 5.691142e-4
GO:0097115 neurexin clustering 5.795400e-4
GO:0046031 ADP metabolic process 5.795400e-4
GO:0019934 cGMP-mediated signaling 5.836128e-4
GO:0043615 astrocyte cell migration 5.947456e-4
GO:0051250 negative regulation of lymphocyte activation 6.038294e-4
GO:0031953 negative regulation of protein autophosphorylation 6.091227e-4
GO:0030334 regulation of cell migration 6.131867e-4
GO:0002718 regulation of cytokine production involved in immune response 6.154425e-4
GO:0045605 negative regulation of epidermal cell differentiation 6.230434e-4
GO:0060056 mammary gland involution 6.339330e-4
GO:0048469 cell maturation 6.437699e-4
GO:0032789 unsaturated monocarboxylic acid metabolic process 6.547660e-4
GO:0042840 D-glucuronate catabolic process 6.547660e-4
GO:0032788 saturated monocarboxylic acid metabolic process 6.547660e-4
GO:0000379 tRNA-type intron splice site recognition and cleavage 6.547660e-4
GO:0006760 folic acid-containing compound metabolic process 6.559225e-4
GO:0044403 symbiosis, encompassing mutualism through parasitism 6.691349e-4
GO:0009167 purine ribonucleoside monophosphate metabolic process 6.870172e-4
GO:0031344 regulation of cell projection organization 6.966720e-4
GO:0071221 cellular response to bacterial lipopeptide 6.988167e-4
GO:0061205 paramesonephric duct development 6.989786e-4
GO:0007098 centrosome cycle 7.137237e-4
GO:0045047 protein targeting to ER 7.162324e-4
GO:0048635 negative regulation of muscle organ development 7.170517e-4
GO:0031334 positive regulation of protein complex assembly 7.200408e-4
GO:2000334 positive regulation of blood microparticle formation 7.251278e-4
GO:2000412 positive regulation of thymocyte migration 7.251278e-4
GO:0021536 diencephalon development 7.307254e-4
GO:0002885 positive regulation of hypersensitivity 7.456551e-4
GO:0042953 lipoprotein transport 7.661912e-4
GO:0045938 positive regulation of circadian sleep/wake cycle, sleep 8.030495e-4
GO:0032103 positive regulation of response to external stimulus 8.107479e-4
GO:0007519 skeletal muscle tissue development 8.136834e-4
GO:0010975 regulation of neuron projection development 8.168505e-4
GO:0050866 negative regulation of cell activation 8.210905e-4
GO:0002862 negative regulation of inflammatory response to antigenic stimulus 8.267239e-4
GO:0031116 positive regulation of microtubule polymerization 8.295118e-4
GO:0032355 response to estradiol stimulus 8.381153e-4
GO:2000594 positive regulation of metanephric DCT cell differentiation 8.406942e-4
GO:0039003 pronephric field specification 8.406942e-4
GO:0072305 negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis 8.406942e-4
GO:0043405 regulation of MAP kinase activity 8.439300e-4
GO:0031099 regeneration 8.657950e-4
GO:0046033 AMP metabolic process 8.797479e-4
GO:0010942 positive regulation of cell death 8.861236e-4
GO:0006909 phagocytosis 9.145452e-4
GO:0051646 mitochondrion localization 9.187269e-4
GO:0055098 response to low-density lipoprotein particle stimulus 9.264359e-4
GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep 9.564213e-4
GO:0031952 regulation of protein autophosphorylation 9.799514e-4
GO:0050764 regulation of phagocytosis 9.801582e-4
GO:0055069 zinc ion homeostasis 9.836760e-4
GO:0010793 regulation of mRNA export from nucleus 1.020377e-3
GO:0015711 organic anion transport 1.048625e-3
GO:0050792 regulation of viral reproduction 1.051142e-3
GO:0048679 regulation of axon regeneration 1.055870e-3
GO:0035880 embryonic nail plate morphogenesis 1.058679e-3
GO:0042320 regulation of circadian sleep/wake cycle, REM sleep 1.071472e-3
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 1.074870e-3
GO:0002700 regulation of production of molecular mediator of immune response 1.099841e-3
GO:0044419 interspecies interaction between organisms 1.103184e-3
GO:0015697 quaternary ammonium group transport 1.107039e-3
GO:0061360 optic chiasma development 1.123965e-3
GO:0035799 ureter maturation 1.123965e-3
GO:2000597 positive regulation of optic nerve formation 1.123965e-3
GO:0021650 vestibulocochlear nerve formation 1.123965e-3
GO:0021633 optic nerve structural organization 1.123965e-3
GO:0048532 anatomical structure arrangement 1.133244e-3
GO:0046069 cGMP catabolic process 1.148764e-3
GO:0070670 response to interleukin-4 1.150058e-3
GO:0002863 positive regulation of inflammatory response to antigenic stimulus 1.159679e-3
GO:0010592 positive regulation of lamellipodium assembly 1.166518e-3
GO:0051280 negative regulation of release of sequestered calcium ion into cytosol 1.173749e-3
GO:0048069 eye pigmentation 1.175583e-3
GO:0009396 folic acid-containing compound biosynthetic process 1.175583e-3
GO:0030307 positive regulation of cell growth 1.178566e-3
GO:0018298 protein-chromophore linkage 1.181327e-3
GO:0050766 positive regulation of phagocytosis 1.188872e-3
GO:0001558 regulation of cell growth 1.230903e-3
GO:0072003 kidney rudiment formation 1.268490e-3
GO:0021562 vestibulocochlear nerve development 1.268490e-3
GO:0051597 response to methylmercury 1.316368e-3
GO:0048545 response to steroid hormone stimulus 1.318155e-3
GO:0008202 steroid metabolic process 1.320503e-3
GO:0032689 negative regulation of interferon-gamma production 1.402027e-3
GO:0032722 positive regulation of chemokine production 1.427409e-3
GO:0034113 heterotypic cell-cell adhesion 1.430973e-3
GO:0042773 ATP synthesis coupled electron transport 1.437634e-3
GO:0002407 dendritic cell chemotaxis 1.446447e-3
GO:0046459 short-chain fatty acid metabolic process 1.446447e-3
GO:0021761 limbic system development 1.452277e-3
GO:0009108 coenzyme biosynthetic process 1.455449e-3
GO:0005996 monosaccharide metabolic process 1.472311e-3
GO:0060363 cranial suture morphogenesis 1.472583e-3
GO:0046641 positive regulation of alpha-beta T cell proliferation 1.476916e-3
GO:0042060 wound healing 1.480179e-3
GO:0006561 proline biosynthetic process 1.481975e-3
GO:0060040 retinal bipolar neuron differentiation 1.545576e-3
GO:0042276 error-prone translesion synthesis 1.545576e-3
GO:2000696 regulation of epithelial cell differentiation involved in kidney development 1.555646e-3
GO:0072307 regulation of metanephric nephron tubule epithelial cell differentiation 1.584448e-3
GO:0009612 response to mechanical stimulus 1.594591e-3
GO:0009179 purine ribonucleoside diphosphate metabolic process 1.608897e-3
GO:0050830 defense response to Gram-positive bacterium 1.615072e-3
GO:0048520 positive regulation of behavior 1.619125e-3
GO:0043065 positive regulation of apoptosis 1.663997e-3
GO:0061379 inferior colliculus development 1.665731e-3
GO:0061381 cell migration in diencephalon 1.665731e-3
GO:0061374 mammillothalamic axonal tract development 1.665731e-3
GO:0046292 formaldehyde metabolic process 1.665731e-3
GO:0021855 hypothalamus cell migration 1.665731e-3
GO:0032387 negative regulation of intracellular transport 1.688523e-3
GO:0010720 positive regulation of cell development 1.696387e-3
GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation 1.708361e-3
GO:0030852 regulation of granulocyte differentiation 1.713191e-3
GO:0030854 positive regulation of granulocyte differentiation 1.715203e-3
GO:0006732 coenzyme metabolic process 1.738061e-3
GO:0002920 regulation of humoral immune response 1.738665e-3
GO:0071447 cellular response to hydroperoxide 1.778682e-3
GO:0015911 plasma membrane long-chain fatty acid transport 1.778682e-3
GO:0018149 peptide cross-linking 1.786738e-3
GO:0060323 head morphogenesis 1.794735e-3
GO:0021943 formation of radial glial scaffolds 1.800332e-3
GO:0010738 regulation of protein kinase A signaling cascade 1.814212e-3
GO:0034284 response to monosaccharide stimulus 1.818642e-3
GO:0034969 histone arginine methylation 1.818693e-3
GO:0006360 transcription from RNA polymerase I promoter 1.830846e-3
GO:0010763 positive regulation of fibroblast migration 1.830846e-3
GO:0032649 regulation of interferon-gamma production 1.845607e-3
GO:0003339 regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 1.847400e-3
GO:0051299 centrosome separation 1.861409e-3
GO:0048676 axon extension involved in development 1.940797e-3
GO:0002682 regulation of immune system process 1.976644e-3
GO:0060554 induction of necroptosis of activated-T cells 1.982052e-3
GO:0006104 succinyl-CoA metabolic process 1.982052e-3
GO:0043068 positive regulation of programmed cell death 1.984023e-3
GO:0060538 skeletal muscle organ development 1.993987e-3
GO:0060325 face morphogenesis 2.010085e-3
GO:0009311 oligosaccharide metabolic process 2.071716e-3
GO:0031112 positive regulation of microtubule polymerization or depolymerization 2.097381e-3
GO:0009566 fertilization 2.160652e-3
GO:0001805 positive regulation of type III hypersensitivity 2.180903e-3
GO:0050854 regulation of antigen receptor-mediated signaling pathway 2.210664e-3
GO:0090072 positive regulation of sodium ion transport via voltage-gated sodium channel activity 2.221943e-3
GO:0046666 retinal cell programmed cell death 2.221943e-3
GO:0001812 positive regulation of type I hypersensitivity 2.221943e-3
GO:0050806 positive regulation of synaptic transmission 2.233272e-3
GO:0045368 positive regulation of interleukin-13 biosynthetic process 2.280744e-3
GO:0001959 regulation of cytokine-mediated signaling pathway 2.298643e-3
GO:0002063 chondrocyte development 2.302067e-3
GO:0048515 spermatid differentiation 2.322702e-3
GO:0071895 odontoblast differentiation 2.331186e-3
GO:0030195 negative regulation of blood coagulation 2.335997e-3
GO:0007165 signal transduction 2.397618e-3
GO:0050900 leukocyte migration 2.476139e-3
GO:0051495 positive regulation of cytoskeleton organization 2.506636e-3
GO:0034383 low-density lipoprotein particle clearance 2.523089e-3
GO:0007530 sex determination 2.575594e-3
GO:0043507 positive regulation of JUN kinase activity 2.585788e-3
GO:0032680 regulation of tumor necrosis factor production 2.585788e-3
GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus 2.594591e-3
GO:0097022 lymphocyte migration into lymph node 2.618839e-3
GO:0072610 interleukin-12 secretion 2.618839e-3
GO:0070571 negative regulation of neuron projection regeneration 2.631415e-3
GO:0051130 positive regulation of cellular component organization 2.643726e-3
GO:0050857 positive regulation of antigen receptor-mediated signaling pathway 2.696989e-3
GO:0002889 regulation of immunoglobulin mediated immune response 2.703943e-3
GO:0007041 lysosomal transport 2.715702e-3
GO:0008347 glial cell migration 2.751419e-3
GO:0021861 forebrain radial glial cell differentiation 2.751970e-3
GO:0010171 body morphogenesis 2.760728e-3
GO:0045063 T-helper 1 cell differentiation 2.762294e-3
GO:0010996 response to auditory stimulus 2.776185e-3
GO:0030328 prenylcysteine catabolic process 2.776185e-3
GO:0015969 guanosine tetraphosphate metabolic process 2.776185e-3
GO:0002638 negative regulation of immunoglobulin production 2.776185e-3
GO:0001811 negative regulation of type I hypersensitivity 2.776185e-3
GO:0042742 defense response to bacterium 2.817663e-3
GO:0009746 response to hexose stimulus 2.820092e-3
GO:0043506 regulation of JUN kinase activity 2.857661e-3
GO:0007320 insemination 2.878723e-3
GO:0044003 modification by symbiont of host morphology or physiology 2.881171e-3
GO:0045348 positive regulation of MHC class II biosynthetic process 2.882515e-3
GO:0048592 eye morphogenesis 2.892307e-3
GO:0046939 nucleotide phosphorylation 2.916830e-3
GO:0046381 CMP-N-acetylneuraminate metabolic process 2.917285e-3
GO:0030595 leukocyte chemotaxis 2.922663e-3
GO:0048732 gland development 2.925894e-3
GO:0046037 GMP metabolic process 2.929226e-3
GO:0034088 maintenance of mitotic sister chromatid cohesion 2.929226e-3
GO:0000086 G2/M transition of mitotic cell cycle 2.977353e-3
GO:0031111 negative regulation of microtubule polymerization or depolymerization 2.981949e-3
GO:0032329 serine transport 3.015800e-3
GO:0051919 positive regulation of fibrinolysis 3.015800e-3
GO:0033563 dorsal/ventral axon guidance 3.015800e-3
GO:0051615 histamine uptake 3.028922e-3
GO:0033603 positive regulation of dopamine secretion 3.028922e-3
GO:0034498 early endosome to Golgi transport 3.028922e-3
GO:0060900 embryonic camera-type eye formation 3.060332e-3
GO:0071780 mitotic cell cycle G2/M transition checkpoint 3.100807e-3
GO:0032781 positive regulation of ATPase activity 3.119132e-3
GO:0042558 pteridine-containing compound metabolic process 3.208983e-3
GO:0030001 metal ion transport 3.210152e-3
GO:0070371 ERK1 and ERK2 cascade 3.273658e-3
GO:0070076 histone lysine demethylation 3.273658e-3
GO:0030516 regulation of axon extension 3.285355e-3
GO:0045058 T cell selection 3.294595e-3
GO:0002820 negative regulation of adaptive immune response 3.403151e-3
GO:0006813 potassium ion transport 3.414038e-3
GO:2000756 regulation of peptidyl-lysine acetylation 3.430795e-3
GO:0021983 pituitary gland development 3.434257e-3
GO:0060759 regulation of response to cytokine stimulus 3.456453e-3
GO:0048193 Golgi vesicle transport 3.469065e-3
GO:0031345 negative regulation of cell projection organization 3.494988e-3
GO:0014012 peripheral nervous system axon regeneration 3.516944e-3
GO:0032023 trypsinogen activation 3.533920e-3
GO:0061037 negative regulation of cartilage development 3.586373e-3
GO:0050765 negative regulation of phagocytosis 3.586373e-3
GO:0045627 positive regulation of T-helper 1 cell differentiation 3.621755e-3
GO:0002830 positive regulation of type 2 immune response 3.621755e-3
GO:0035106 operant conditioning 3.633477e-3
GO:0045860 positive regulation of protein kinase activity 3.634307e-3
GO:0048845 venous blood vessel morphogenesis 3.648412e-3
GO:0045596 negative regulation of cell differentiation 3.651806e-3
GO:0031645 negative regulation of neurological system process 3.710845e-3
GO:0032530 regulation of microvillus organization 3.724835e-3
GO:0031529 ruffle organization 3.739761e-3
GO:0051971 positive regulation of transmission of nerve impulse 3.742690e-3
GO:0048639 positive regulation of developmental growth 3.743792e-3
GO:0032496 response to lipopolysaccharide 3.773806e-3
GO:0031113 regulation of microtubule polymerization 3.776863e-3
GO:0006006 glucose metabolic process 3.790777e-3
GO:0014059 regulation of dopamine secretion 3.812517e-3
GO:0010812 negative regulation of cell-substrate adhesion 3.888882e-3
GO:0033273 response to vitamin 3.892586e-3
GO:0097026 dendritic cell dendrite assembly 3.897621e-3
GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c 3.897621e-3
GO:0002237 response to molecule of bacterial origin 3.903431e-3
GO:0051494 negative regulation of cytoskeleton organization 3.904519e-3
GO:0010639 negative regulation of organelle organization 3.946589e-3
GO:0060019 radial glial cell differentiation 3.970909e-3
GO:0048524 positive regulation of viral reproduction 3.983897e-3
GO:0002762 negative regulation of myeloid leukocyte differentiation 3.983897e-3
GO:0032713 negative regulation of interleukin-4 production 4.005154e-3
GO:0070507 regulation of microtubule cytoskeleton organization 4.041647e-3
GO:0001960 negative regulation of cytokine-mediated signaling pathway 4.049078e-3
GO:0002669 positive regulation of T cell anergy 4.064748e-3
GO:2000171 negative regulation of dendrite development 4.093361e-3
GO:0050855 regulation of B cell receptor signaling pathway 4.170495e-3
GO:0010769 regulation of cell morphogenesis involved in differentiation 4.179865e-3
GO:0060992 response to fungicide 4.193822e-3
GO:0010544 negative regulation of platelet activation 4.211374e-3
GO:0052547 regulation of peptidase activity 4.243345e-3
GO:0018195 peptidyl-arginine modification 4.275571e-3
GO:0035710 CD4-positive, alpha-beta T cell activation 4.339130e-3
GO:0022409 positive regulation of cell-cell adhesion 4.347740e-3
GO:0032615 interleukin-12 production 4.353571e-3
GO:0043310 negative regulation of eosinophil degranulation 4.372480e-3
GO:2000409 positive regulation of T cell extravasation 4.372480e-3
GO:0035705 T-helper 17 cell chemotaxis 4.372480e-3
GO:0033210 leptin-mediated signaling pathway 4.372480e-3
GO:0035696 monocyte extravasation 4.372480e-3
GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation 4.372480e-3
GO:0006637 acyl-CoA metabolic process 4.382318e-3
GO:0048170 positive regulation of long-term neuronal synaptic plasticity 4.462117e-3
GO:0002678 positive regulation of chronic inflammatory response 4.462117e-3
GO:0030223 neutrophil differentiation 4.462117e-3
GO:0022600 digestive system process 4.496141e-3
GO:0072300 positive regulation of metanephric glomerulus development 4.521225e-3
GO:0033605 positive regulation of catecholamine secretion 4.521225e-3
GO:2000378 negative regulation of reactive oxygen species metabolic process 4.549913e-3
GO:2000121 regulation of removal of superoxide radicals 4.555213e-3
GO:0015825 L-serine transport 4.586737e-3
GO:0010519 negative regulation of phospholipase activity 4.640939e-3
GO:0060452 positive regulation of cardiac muscle contraction 4.640939e-3
GO:0032729 positive regulation of interferon-gamma production 4.650234e-3
GO:0043044 ATP-dependent chromatin remodeling 4.679668e-3
GO:0060841 venous blood vessel development 4.731147e-3
GO:0031646 positive regulation of neurological system process 4.767000e-3
GO:0051970 negative regulation of transmission of nerve impulse 4.803267e-3
GO:0090023 positive regulation of neutrophil chemotaxis 4.813166e-3
GO:0015893 drug transport 4.869922e-3
GO:2000401 regulation of lymphocyte migration 4.881804e-3
GO:0070972 protein localization in endoplasmic reticulum 4.890636e-3
GO:0070849 response to epidermal growth factor stimulus 4.890636e-3
GO:0042147 retrograde transport, endosome to Golgi 4.891250e-3
GO:0032642 regulation of chemokine production 4.893218e-3
GO:0044255 cellular lipid metabolic process 4.978024e-3
GO:0046635 positive regulation of alpha-beta T cell activation 4.980716e-3
GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 4.994429e-3
GO:0006482 protein demethylation 4.994429e-3
GO:0061387 regulation of extent of cell growth 5.033027e-3
GO:0045074 regulation of interleukin-10 biosynthetic process 5.035046e-3
GO:0010560 positive regulation of glycoprotein biosynthetic process 5.035046e-3
GO:0050865 regulation of cell activation 5.035169e-3
GO:0010040 response to iron(II) ion 5.089234e-3
GO:0001774 microglial cell activation 5.089234e-3
GO:0045081 negative regulation of interleukin-10 biosynthetic process 5.101209e-3
GO:0010389 regulation of G2/M transition of mitotic cell cycle 5.133098e-3
GO:0002702 positive regulation of production of molecular mediator of immune response 5.192422e-3
GO:0008333 endosome to lysosome transport 5.194427e-3
GO:0070542 response to fatty acid 5.205325e-3
GO:2000602 regulation of interphase of mitotic cell cycle 5.209651e-3
GO:0016577 histone demethylation 5.210328e-3
GO:0035246 peptidyl-arginine N-methylation 5.280983e-3
GO:0043923 positive regulation by host of viral transcription 5.290298e-3
GO:0002695 negative regulation of leukocyte activation 5.369701e-3
GO:0043551 regulation of phosphatidylinositol 3-kinase activity 5.426543e-3
GO:0045071 negative regulation of viral genome replication 5.437517e-3