UBERON:0002303
From FANTOM5_SSTAR
| Name: | juxtaglomerular apparatus | ||
|---|---|---|---|
| Definition: | "An anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate[GO]. a microscopic structure in the kidney, which regulates the function of each nephron. The juxtaglomerular apparatus is named for its proximity to the glomerulus: it is found between the vascular pole of the renal corpuscle and the returning distal convoluted tubule of the same nephron. This location is critical to its function in regulating renal blood flow and glomerular filtration rate. The three cellular components of the apparatus are the macula densa, extraglomerular mesangial cells, and juxtaglomerular cells (also known as granular cells)[WP]." [GO:0072206, Wikipedia:Juxtaglomerular_apparatus] | ||
| Xrefs: |
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| Synonyms: | "juxtaglomerular complex" EXACT [] | ||
| Alt_id: | UBERON:FMA_83599-MA_0002546 | ||
| Subset: | uberon_slim |
Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data
Parents
| is_a: | UBERON:0000477(anatomical cluster),UBERON:0006554(urinary system structure) |
|---|---|
| part_of: | UBERON:0001225(cortex of kidney) |
Children
| part of: | UBERON:0002321 (extraglomerular mesangium),CL:1000618 (juxtaglomerular complex cell) |
|---|
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology
Human (Homo sapiens)
- 11518-119H6 (Renal Mesangial Cells, donor1)
- 11598-120H5 (Renal Mesangial Cells, donor2)
- 11679-122H5 (Renal Mesangial Cells, donor3)
Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0002303 (juxtaglomerular apparatus), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
| P-value | FFCP | Short description |
|---|---|---|
| 2.34e-79 | FFCP PHASE2:Hg19::chr2:133426030..133426041,-#_dcbda99bebc66206d6ce6bef07b59d2e | p@chr2:133426030..133426041, - |
| 2.34e-79 | FFCP PHASE1:Hg19::chr2:133426030..133426041,-#_dcbda99bebc66206d6ce6bef07b59d2e | p@chr2:133426030..133426041, - |
| 3.49e-79 | FFCP PHASE1:Hg19::chr1:51791596..51791607,-#_592857946cdb2026e8c371ae350f7fb5 | p23@TTC39A |
| 3.49e-79 | FFCP PHASE2:Hg19::chr1:51791596..51791607,-#_592857946cdb2026e8c371ae350f7fb5 | p23@TTC39A |
| 2.03e-66 | FFCP PHASE1:Hg19::chr2:133426106..133426117,-#_aed7f16c48d50e77fadd3cf2b99272fd | p@chr2:133426106..133426117, - |
| 2.03e-66 | FFCP PHASE2:Hg19::chr2:133426106..133426117,-#_aed7f16c48d50e77fadd3cf2b99272fd | p@chr2:133426106..133426117, - |
| 1.46e-50 | FFCP PHASE2:Hg19::chr10:134535354..134535366,-#_63f4d6c5597dea3779358f72a403160b | p@chr10:134535354..134535366, - |
| 1.46e-50 | FFCP PHASE2:Hg19::chr10:102495136..102495146,+#_63f4d6c5597dea3779358f72a403160b | p8@PAX2 |
| 1.46e-50 | FFCP PHASE1:Hg19::chr10:134535354..134535366,-#_63f4d6c5597dea3779358f72a403160b | p@chr10:134535354..134535366, - |
| 1.46e-50 | FFCP PHASE1:Hg19::chr10:102495136..102495146,+#_63f4d6c5597dea3779358f72a403160b | p8@PAX2 |
| 3.11e-50 | FFCP PHASE1:Hg19::chr17:17480803..17480814,-#_bdf7aff4d559ec3b983b96249c02d6c5 | p19@PEMT |
| 3.11e-50 | FFCP PHASE2:Hg19::chr17:17480803..17480814,-#_bdf7aff4d559ec3b983b96249c02d6c5 | p19@PEMT |
| 4.52e-50 | FFCP PHASE1:Hg19::chr9:81641483..81641491,-#_c195db9aaefab477c1ebb6184bc3f09e | p@chr9:81641483..81641491, - |
| 4.52e-50 | FFCP PHASE2:Hg19::chr10:102505655..102505689,+#_c195db9aaefab477c1ebb6184bc3f09e | p10@PAX2 |
| 4.52e-50 | FFCP PHASE1:Hg19::chr10:102505655..102505689,+#_c195db9aaefab477c1ebb6184bc3f09e | p10@PAX2 |
| 4.52e-50 | FFCP PHASE2:Hg19::chr9:81641483..81641491,-#_c195db9aaefab477c1ebb6184bc3f09e | p@chr9:81641483..81641491, - |
| 8.98e-41 | FFCP PHASE2:Hg19::chr17:171082..171101,+#_3da6e1735aff62cd330456d0dbbf3141 | p@chr17:171082..171101, + |
| 8.98e-41 | FFCP PHASE1:Hg19::chr17:171082..171101,+#_3da6e1735aff62cd330456d0dbbf3141 | p@chr17:171082..171101, + |
| 1.1e-40 | FFCP PHASE2:Hg19::chr3:172384246..172384250,+#_314df96c7ca898e294c045524fa90e7c | p@chr3:172384246..172384250, + |
| 1.1e-40 | FFCP PHASE1:Hg19::chr3:172384246..172384250,+#_314df96c7ca898e294c045524fa90e7c | p@chr3:172384246..172384250, + |
| 1.64e-40 | FFCP PHASE2:Hg19::chr1:45087902..45087912,+#_dbb14b674816f6fd1c8d1c4848847a6e | p@chr1:45087902..45087912, + |
| 1.64e-40 | FFCP PHASE1:Hg19::chr1:45087902..45087912,+#_dbb14b674816f6fd1c8d1c4848847a6e | p@chr1:45087902..45087912, + |
| 3.68e-40 | FFCP PHASE2:Hg19::chr10:102505552..102505563,+#_4813e042b9e11fe773988ed91e77c0a9 | p5@PAX2 |
| 3.68e-40 | FFCP PHASE1:Hg19::chr10:102505552..102505563,+#_4813e042b9e11fe773988ed91e77c0a9 | p5@PAX2 |
| 8.2e-37 | FFCP PHASE2:Hg19::chr10:102505312..102505320,+#_8751b21fa63c0c0ef3b562ca89090b60 | p6@PAX2 |
| 8.2e-37 | FFCP PHASE1:Hg19::chr10:102505312..102505320,+#_8751b21fa63c0c0ef3b562ca89090b60 | p6@PAX2 |
| 9.84e-37 | FFCP PHASE2:Hg19::chr9:126131131..126131159,+#_dd87a773d2cac3e879ca38ae25c20a61 | p3@CRB2 |
| 9.84e-37 | FFCP PHASE1:Hg19::chr9:126131131..126131159,+#_dd87a773d2cac3e879ca38ae25c20a61 | p3@CRB2 |
| 6.0e-34 | FFCP PHASE1:Hg19::chr2:113984760..113984792,+#_89389f6a33a931850ffea315292e2098 | p@chr2:113984760..113984792, + |
| 6.0e-34 | FFCP PHASE2:Hg19::chr2:113984760..113984792,+#_89389f6a33a931850ffea315292e2098 | p@chr2:113984760..113984792, + |
| 7.05e-34 | FFCP PHASE2:Hg19::chr11:555661..555679,+#_95788940942799a20fdc43c3dce0932b | p@chr11:555661..555679, + |
| 7.05e-34 | FFCP PHASE2:Hg19::chr1:858638..858648,+#_95788940942799a20fdc43c3dce0932b | p@chr1:858638..858648, + |
| 7.05e-34 | FFCP PHASE2:Hg19::chr7:27164585..27164612,-#_95788940942799a20fdc43c3dce0932b | p@chr7:27164585..27164612, - |
| 7.05e-34 | FFCP PHASE1:Hg19::chr11:555661..555679,+#_95788940942799a20fdc43c3dce0932b | p@chr11:555661..555679, + |
| 7.05e-34 | FFCP PHASE1:Hg19::chr1:858638..858648,+#_95788940942799a20fdc43c3dce0932b | p@chr1:858638..858648, + |
| 7.05e-34 | FFCP PHASE1:Hg19::chr7:27164585..27164612,-#_95788940942799a20fdc43c3dce0932b | p@chr7:27164585..27164612, - |
| 8.39e-34 | FFCP PHASE2:Hg19::chr10:73848549..73848564,-#_4ae1e0d766cd940576e6bac067ada613 | p13@SPOCK2 |
| 8.39e-34 | FFCP PHASE1:Hg19::chr10:73848549..73848564,-#_4ae1e0d766cd940576e6bac067ada613 | p13@SPOCK2 |
| 1.17e-33 | FFCP PHASE2:Hg19::chr11:118477144..118477156,+#_78f145044ee25735cf8b7c9d391d185a | p25@PHLDB1 |
| 1.17e-33 | FFCP PHASE1:Hg19::chr11:118477144..118477156,+#_78f145044ee25735cf8b7c9d391d185a | p25@PHLDB1 |
| 3.35e-32 | FFCP PHASE1:Hg19::chr2:693362..693373,+#_8e66c8b5855db7d1bbf581d695413d2a | p@chr2:693362..693373, + |
| 3.35e-32 | FFCP PHASE2:Hg19::chr2:693362..693373,+#_8e66c8b5855db7d1bbf581d695413d2a | p@chr2:693362..693373, + |
| 2.54e-31 | FFCP PHASE1:Hg19::chrX:106146562..106146577,-#_4ca2126aba23e0e8c89e556e2831ee7d | p1@RIPPLY1 |
| 2.54e-31 | FFCP PHASE2:Hg19::chrX:106146562..106146577,-#_4ca2126aba23e0e8c89e556e2831ee7d | p1@RIPPLY1 |
| 8.05e-30 | FFCP PHASE1:Hg19::chr17:171147..171161,+#_f6dab331726d6e23a7368735fb29924b | p@chr17:171147..171161, + |
| 8.05e-30 | FFCP PHASE2:Hg19::chr17:171147..171161,+#_f6dab331726d6e23a7368735fb29924b | p@chr17:171147..171161, + |
| 2.96e-29 | FFCP PHASE1:Hg19::chr2:165477405..165477418,-#_3b18f523e760e777c7540865e9a20071 | p@chr2:165477405..165477418, - |
| 2.96e-29 | FFCP PHASE2:Hg19::chr2:165477405..165477418,-#_3b18f523e760e777c7540865e9a20071 | p@chr2:165477405..165477418, - |
| 4.55e-29 | FFCP PHASE2:Hg19::chr1:874109..874143,+#_9676b015c49cf446beb00b54fa3b7de2 | p@chr1:874109..874143, + |
| 4.55e-29 | FFCP PHASE1:Hg19::chr1:874109..874143,+#_9676b015c49cf446beb00b54fa3b7de2 | p@chr1:874109..874143, + |
| 1.43e-28 | FFCP PHASE2:Hg19::chr2:113999199..113999214,+#_0383a530910c5794abae63b757c70ce2 | p@chr2:113999199..113999214, + |
| 1.43e-28 | FFCP PHASE1:Hg19::chr2:113999199..113999214,+#_0383a530910c5794abae63b757c70ce2 | p@chr2:113999199..113999214, + |
| 1.83e-27 | FFCP PHASE2:Hg19::chr20:6034598..6034603,-#_49dcb18d7cff528c9b1d85eeddeda35a | p7@LRRN4 |
| 1.83e-27 | FFCP PHASE2:Hg19::chr16:86604624..86604648,+#_49dcb18d7cff528c9b1d85eeddeda35a | p@chr16:86604624..86604648, + |
| 1.83e-27 | FFCP PHASE1:Hg19::chr16:86604624..86604648,+#_49dcb18d7cff528c9b1d85eeddeda35a | p@chr16:86604624..86604648, + |
| 1.83e-27 | FFCP PHASE1:Hg19::chr20:6034598..6034603,-#_49dcb18d7cff528c9b1d85eeddeda35a | p7@LRRN4 |
| 2.74e-27 | FFCP PHASE2:Hg19::chr19:56091499..56091517,-#_fd3ed4ddcfd6a4f24892294a1260e95b | p@chr19:56091499..56091517, - |
| 2.74e-27 | FFCP PHASE1:Hg19::chr19:56091499..56091517,-#_fd3ed4ddcfd6a4f24892294a1260e95b | p@chr19:56091499..56091517, - |
| 2.78e-26 | FFCP PHASE2:Hg19::chr9:112260040..112260045,+#_ee3cd0787f5a9c9fefa53afba5e0e235 | p@chr9:112260040..112260045, + |
| 2.78e-26 | FFCP PHASE1:Hg19::chr9:112260040..112260045,+#_ee3cd0787f5a9c9fefa53afba5e0e235 | p@chr9:112260040..112260045, + |
| 4.63e-26 | FFCP PHASE2:Hg19::chr22:30645170..30645182,-#_efebf90341ea2a3bf28b38df54ae58b5 | p@chr22:30645170..30645182, - |
| 4.63e-26 | FFCP PHASE1:Hg19::chr22:30645170..30645182,-#_efebf90341ea2a3bf28b38df54ae58b5 | p@chr22:30645170..30645182, - |
| 7.14e-26 | FFCP PHASE2:Hg19::chr8:22419319..22419327,+#_92a1ffa85605d59efcea50f310780391 | p@chr8:22419319..22419327, + |
| 7.14e-26 | FFCP PHASE1:Hg19::chr8:22419319..22419327,+#_92a1ffa85605d59efcea50f310780391 | p@chr8:22419319..22419327, + |
| 9.18e-26 | FFCP PHASE2:Hg19::chr6:31833005..31833017,-#_1f8ea54c22760bc7cadced968ceda6b9 | p@chr6:31833005..31833017, - |
| 9.18e-26 | FFCP PHASE2:Hg19::chr8:28196820..28196830,+#_1f8ea54c22760bc7cadced968ceda6b9 | p@chr8:28196820..28196830, + |
| 9.18e-26 | FFCP PHASE2:Hg19::chr2:176973165..176973169,-#_1f8ea54c22760bc7cadced968ceda6b9 | p@chr2:176973165..176973169, - |
| 9.18e-26 | FFCP PHASE2:Hg19::chr20:6031540..6031548,-#_1f8ea54c22760bc7cadced968ceda6b9 | p@chr20:6031540..6031548, - |
| 9.18e-26 | FFCP PHASE2:Hg19::chr10:102505946..102505949,+#_1f8ea54c22760bc7cadced968ceda6b9 | p14@PAX2 |
| 9.18e-26 | FFCP PHASE1:Hg19::chr6:31833005..31833017,-#_1f8ea54c22760bc7cadced968ceda6b9 | p@chr6:31833005..31833017, - |
| 9.18e-26 | FFCP PHASE1:Hg19::chr10:102505946..102505949,+#_1f8ea54c22760bc7cadced968ceda6b9 | p14@PAX2 |
| 9.18e-26 | FFCP PHASE2:Hg19::chr11:32457397..32457404,-#_1f8ea54c22760bc7cadced968ceda6b9 | p15@WT1 |
| 9.18e-26 | FFCP PHASE2:Hg19::chr17:15555143..15555150,-#_1f8ea54c22760bc7cadced968ceda6b9 | p12@TRIM16 |
| 9.18e-26 | FFCP PHASE1:Hg19::chr11:32457397..32457404,-#_1f8ea54c22760bc7cadced968ceda6b9 | p15@WT1 |
| 9.18e-26 | FFCP PHASE1:Hg19::chr8:28196820..28196830,+#_1f8ea54c22760bc7cadced968ceda6b9 | p@chr8:28196820..28196830, + |
| 9.18e-26 | FFCP PHASE1:Hg19::chr2:176973165..176973169,-#_1f8ea54c22760bc7cadced968ceda6b9 | p@chr2:176973165..176973169, - |
| 9.18e-26 | FFCP PHASE1:Hg19::chr20:6031540..6031548,-#_1f8ea54c22760bc7cadced968ceda6b9 | p@chr20:6031540..6031548, - |
| 9.18e-26 | FFCP PHASE1:Hg19::chr17:15555143..15555150,-#_1f8ea54c22760bc7cadced968ceda6b9 | p12@TRIM16 |
| 2.37e-25 | FFCP PHASE1:Hg19::chr7:27160553..27160560,+#_b552d88ff11ea0dbd194cfc73970714b | p1@ENST00000523364, p1@uc010kux.1 |
| 2.37e-25 | FFCP PHASE2:Hg19::chr7:27160553..27160560,+#_b552d88ff11ea0dbd194cfc73970714b | p1@ENST00000523364, p1@uc010kux.1 |
| 4.38e-25 | FFCP PHASE1:Hg19::chr7:27219754..27219759,-#_d3043d4d253b6eb896735c921442fa64 | p16@HOXA10 |
| 4.38e-25 | FFCP PHASE2:Hg19::chr7:27219754..27219759,-#_d3043d4d253b6eb896735c921442fa64 | p16@HOXA10 |
| 4.43e-25 | FFCP PHASE2:Hg19::chr1:149908263..149908281,-#_96371ef65c1838106f727bed245bfd0a | p6@MTMR11 |
| 4.43e-25 | FFCP PHASE1:Hg19::chr1:149908263..149908281,-#_96371ef65c1838106f727bed245bfd0a | p6@MTMR11 |
| 7.09e-25 | FFCP PHASE2:Hg19::chr10:102495147..102495159,+#_53872b6be914681a15e6d53b5dd5cd24 | p4@PAX2 |
| 7.09e-25 | FFCP PHASE1:Hg19::chr10:102495147..102495159,+#_53872b6be914681a15e6d53b5dd5cd24 | p4@PAX2 |
| 3.76e-24 | FFCP PHASE1:Hg19::chr1:46797583..46797614,-#_8d62271982664afee71b33b9889835e9 | p@chr1:46797583..46797614, - |
| 3.76e-24 | FFCP PHASE2:Hg19::chr1:46797583..46797614,-#_8d62271982664afee71b33b9889835e9 | p@chr1:46797583..46797614, - |
| 7.62e-24 | FFCP PHASE1:Hg19::chr6:94129519..94129544,+#_159975c4012aa573ef7adf273fe2592d | p@chr6:94129519..94129544, + |
| 7.62e-24 | FFCP PHASE2:Hg19::chr6:94129519..94129544,+#_159975c4012aa573ef7adf273fe2592d | p@chr6:94129519..94129544, + |
| 8.02e-24 | FFCP PHASE1:Hg19::chr2:693380..693398,+#_24ffabb38cf5d188d2484737bbec1d75 | p@chr2:693380..693398, + |
| 8.02e-24 | FFCP PHASE2:Hg19::chr2:693380..693398,+#_24ffabb38cf5d188d2484737bbec1d75 | p@chr2:693380..693398, + |
| 8.98e-24 | FFCP PHASE1:Hg19::chr2:133426077..133426103,-#_a865618d97ec06958853157194dfe2ca | p@chr2:133426077..133426103, - |
| 8.98e-24 | FFCP PHASE2:Hg19::chr2:133426077..133426103,-#_a865618d97ec06958853157194dfe2ca | p@chr2:133426077..133426103, - |
| 1.99e-23 | FFCP PHASE2:Hg19::chr11:32457350..32457361,+#_840bd6886d51d720cad08d0445a87cb9 | p5@WT1-AS |
| 1.99e-23 | FFCP PHASE1:Hg19::chr11:32457350..32457361,+#_840bd6886d51d720cad08d0445a87cb9 | p5@WT1-AS |
| 4.37e-23 | FFCP PHASE2:Hg19::chr2:176968471..176968476,-#_42126684df4c32190250d543a34e91a6 | p@chr2:176968471..176968476, - |
| 4.37e-23 | FFCP PHASE1:Hg19::chr2:176968471..176968476,-#_42126684df4c32190250d543a34e91a6 | p@chr2:176968471..176968476, - |
| 4.89e-23 | FFCP PHASE2:Hg19::chr12:15592437..15592438,+#_1b02a885eba09eb88d88fa7e475d92f9 | p1@ENST00000469884 |
| 4.89e-23 | FFCP PHASE1:Hg19::chr12:15592437..15592438,+#_1b02a885eba09eb88d88fa7e475d92f9 | p1@ENST00000469884 |
