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UBERON:0002371

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Name:bone marrow
Namespace:FANTOM
Definition:"flexible tissue found in the hollow interior of bones. In adults, marrow in large bones produces new blood cells[WP]." [Wikipedia:Bone_marrow]
Xrefs:
links:

AAO:0011007
BTO:0000141
BTO:0000829
EFO:0000868
EV:0100046
FMA:9608
GAID:1287
galen:BoneMarrow
[1]
MA:0000134
MAT:0000084
MESH:A.15.382.216
MIAA:0000084
ncithesaurus:Bone_Marrow
OpenCyc:Mx4rvVm-FpwpEbGdrcN5Y29ycA
SCTID:421320006
VHOG:0001218

XAO:0000123
Synonyms: "anterior kidney" RELATED []
"head kidney" BROAD []
"kidney marrow" RELATED []
"medulla of bone" RELATED [BTO:0000141]
"medulla ossea" EXACT []
"medulla ossium" RELATED LATIN [Wikipedia:Bone_marrow]
"medulla ossium" RELATED [BTO:0000141]
Comments:TODO - create superclass for bone marrow / head kidney. both are portions of tissue in the hematopoetic system. also consider adding as subclass of zone of bone organ for consistency with FMA. See also: Leydig and epigonal organs
Alt_id: UBERON:FMA_9608-MA_0000134-MIAA_0000084-XAO_0000123-ZFA_0000669
Subset: uberon_slim

Ontology association
Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.

link to ontology dataset
data


Parents

is_a:UBERON:0012429(hemopoietic tissue)
part_of:UBERON:0001474(bone element),UBERON:0002390(hematopoietic system),UBERON:0002405(immune system)



Children

derives from:FF:0010192 (human bone marrow - adult sample),FF:0200020 (osteoclast, bone marrow-derived sample),FF:0200029 (hematopoietic stem cell, bone marrow derived sample)
part of:CL:0000556 (megakaryocyte),CL:0000557 (granulocyte monocyte progenitor cell),CL:0002092 (bone marrow cell),CL:0002476 (bone marrow macrophage),CL:0002540 (mesenchymal stem cell of the bone marrow),UBERON:0007195 (stroma of bone marrow),CL:1001610 (bone marrow hematopoietic cell)

Ontology Tree: Loaded from BioPortal


FF samples
It includes FANTOM5 samples that overlay the Uberon ontology


Human (Homo sapiens)

... further results Mouse (Mus musculus)

... further results


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0002371 (bone marrow), sorted by p-values
Analyst: Hideya Kawaji

link to source dataset
human : data
mouse : data


P-valueFFCPShort description
3.02e-119FFCP PHASE1:Hg19::chr1:161187824..161187847,+#_fb288fb0dd4490ba420de939d7b549c6p@chr1:161187824..161187847, +
3.02e-119FFCP PHASE2:Hg19::chr1:161187824..161187847,+#_fb288fb0dd4490ba420de939d7b549c6p@chr1:161187824..161187847, +
7.29e-115FFCP PHASE2:Hg19::chr16:50313426..50313459,+#_0f7bf86989a2da0c0782b39d099bd003p@chr16:50313426..50313459, +
7.29e-115FFCP PHASE1:Hg19::chr16:50313426..50313459,+#_0f7bf86989a2da0c0782b39d099bd003p@chr16:50313426..50313459, +
1.19e-114FFCP PHASE1:Hg19::chr1:161188661..161188679,+#_f05fbde14200f076ddb4fbaa2a643511p@chr1:161188661..161188679, +
1.19e-114FFCP PHASE2:Hg19::chr1:161188661..161188679,+#_f05fbde14200f076ddb4fbaa2a643511p@chr1:161188661..161188679, +
4.24e-113FFCP PHASE2:Hg19::chr18:2847062..2847071,+#_b3c9078f5b6cbfc07d37145982131b60p7@EMILIN2
4.24e-113FFCP PHASE1:Hg19::chr18:2847062..2847071,+#_b3c9078f5b6cbfc07d37145982131b60p7@EMILIN2
1.01e-112FFCP PHASE2:Hg19::chr7:77050554..77050601,+#_2e0774b534916bd0083c05f67a9b4bdcp@chr7:77050554..77050601, +
1.01e-112FFCP PHASE1:Hg19::chr7:77050554..77050601,+#_2e0774b534916bd0083c05f67a9b4bdcp@chr7:77050554..77050601, +
1.9e-111FFCP PHASE1:Hg19::chr1:161188746..161188758,+#_c358df2711241791bf4fc993444f90c0p@chr1:161188746..161188758, +
1.9e-111FFCP PHASE2:Hg19::chr1:161188746..161188758,+#_c358df2711241791bf4fc993444f90c0p@chr1:161188746..161188758, +
7.78e-111FFCP PHASE2:Hg19::chr17:7482481..7482508,-#_fea5d07b0a7ac31f193be8b2dd36553dp@chr17:7482481..7482508, -
7.78e-111FFCP PHASE1:Hg19::chr17:7482481..7482508,-#_fea5d07b0a7ac31f193be8b2dd36553dp@chr17:7482481..7482508, -
2.59e-110FFCP PHASE1:Hg19::chr19:18288651..18288682,+#_8420d68ef0d380fba0fee47cc4bf47c6p5@IFI30
2.59e-110FFCP PHASE2:Hg19::chr19:18288651..18288682,+#_8420d68ef0d380fba0fee47cc4bf47c6p5@IFI30
5.16e-109FFCP PHASE2:Hg19::chr4:3387239..3387324,-#_72086cba4aa5b69ab20eee096ff962c4p@chr4:3387239..3387324, -
5.16e-109FFCP PHASE1:Hg19::chr4:3387239..3387324,-#_72086cba4aa5b69ab20eee096ff962c4p@chr4:3387239..3387324, -
1.18e-107FFCP PHASE1:Hg19::chr7:2832730..2832791,+#_536c1801722acc7850108a0aefb2bac6+, p@chr7:2832730..2832791
1.18e-107FFCP PHASE2:Hg19::chr7:2832730..2832791,+#_536c1801722acc7850108a0aefb2bac6p@chr7:2832730..2832791, +
7.69e-107FFCP PHASE2:Hg19::chr5:180242646..180242657,-#_00a7aef9980fdd13dbb72f4993ca7431p15@MGAT1
7.69e-107FFCP PHASE1:Hg19::chr5:180242646..180242657,-#_00a7aef9980fdd13dbb72f4993ca7431p15@MGAT1
2.19e-106FFCP PHASE2:Hg19::chr19:18288828..18288861,+#_86423e31ee228d41f7578b87f9cbd65fp7@IFI30
2.19e-106FFCP PHASE1:Hg19::chr19:18288828..18288861,+#_86423e31ee228d41f7578b87f9cbd65fp7@IFI30
4.2e-106FFCP PHASE1:Hg19::chr1:111743000..111743011,+#_edaee5933a9448bc812c28369aaa999dp8@CHI3L2
4.2e-106FFCP PHASE2:Hg19::chr1:111743000..111743011,+#_edaee5933a9448bc812c28369aaa999dp8@CHI3L2
9.25e-106FFCP PHASE2:Hg19::chr17:40168698..40168726,-#_9d42f22ed206a684bd783c92e03ceafcp1@AK126179
9.25e-106FFCP PHASE1:Hg19::chr17:40168698..40168726,-#_9d42f22ed206a684bd783c92e03ceafcp1@AK126179
6.0e-105FFCP PHASE1:Hg19::chr2:145429606..145429658,+#_fe5c7ce6cec85a35db1f1742408f3fbep@chr2:145429606..145429658, +
6.0e-105FFCP PHASE2:Hg19::chr2:145429606..145429658,+#_fe5c7ce6cec85a35db1f1742408f3fbep@chr2:145429606..145429658, +
1.54e-104FFCP PHASE1:Hg19::chr19:18286116..18286156,+#_37ab9a6aa1d27a2728af9a15e0a16317p@chr19:18286116..18286156, +
1.54e-104FFCP PHASE2:Hg19::chr19:18286116..18286156,+#_37ab9a6aa1d27a2728af9a15e0a16317p@chr19:18286116..18286156, +
3.16e-104FFCP PHASE2:Hg19::chr17:72542163..72542182,-#_3a3a7b8f3ab968ecc956e6614f9a10c6p2@CD300C
3.16e-104FFCP PHASE1:Hg19::chr17:72542163..72542182,-#_3a3a7b8f3ab968ecc956e6614f9a10c6p2@CD300C
2.33e-103FFCP PHASE2:Hg19::chr2:38358217..38358244,+#_525ade17346c48bec4dee470edcf267cp1@CYP1B1-AS1
2.33e-103FFCP PHASE1:Hg19::chr2:38358217..38358244,+#_525ade17346c48bec4dee470edcf267cp1@CYP1B1-AS1
3.32e-103FFCP PHASE2:Hg19::chr15:65174546..65174583,-#_275d4c4bbe0182dfc53910d2a26aa518p@chr15:65174546..65174583, -
3.32e-103FFCP PHASE1:Hg19::chr15:65174546..65174583,-#_275d4c4bbe0182dfc53910d2a26aa518p@chr15:65174546..65174583, -
6.1e-103FFCP PHASE2:Hg19::chr4:159727272..159727307,+#_13028d7e697d6a5ca6fa36e0abc17c4cp7@FNIP2
6.1e-103FFCP PHASE1:Hg19::chr4:159727272..159727307,+#_13028d7e697d6a5ca6fa36e0abc17c4cp7@FNIP2
1.77e-102FFCP PHASE1:Hg19::chr4:185314125..185314143,-#_356752c12b6ba55692e1e2ac59a532d1p@chr4:185314125..185314143, -
1.77e-102FFCP PHASE2:Hg19::chr4:185314125..185314143,-#_356752c12b6ba55692e1e2ac59a532d1p@chr4:185314125..185314143, -
3.48e-102FFCP PHASE2:Hg19::chr3:149531627..149531651,+#_4c67fa311721a70714ee3ed1474222ebp7@RNF13
3.48e-102FFCP PHASE1:Hg19::chr3:149531627..149531651,+#_4c67fa311721a70714ee3ed1474222ebp7@RNF13
9.05e-102FFCP PHASE1:Hg19::chr19:52299474..52299504,-#_9a853885e7d51cfad8df78758a993a25p@chr19:52299474..52299504, -
9.05e-102FFCP PHASE2:Hg19::chr19:52299474..52299504,-#_9a853885e7d51cfad8df78758a993a25p@chr19:52299474..52299504, -
1.3e-101FFCP PHASE2:Hg19::chr1:161188686..161188721,+#_5356f7331a9a7f1e4acca94148ff9da0+, p@chr1:161188686..161188721
1.3e-101FFCP PHASE1:Hg19::chr1:161188686..161188721,+#_5356f7331a9a7f1e4acca94148ff9da0p@chr1:161188686..161188721, +
2.05e-101FFCP PHASE1:Hg19::chr5:131280548..131280574,-#_544475e36132fd7889ad7b5283b019bdp1@ENST00000425320
2.05e-101FFCP PHASE2:Hg19::chr5:131280548..131280574,-#_544475e36132fd7889ad7b5283b019bdp1@ENST00000425320
2.11e-101FFCP PHASE2:Hg19::chr2:119726719..119726744,+#_dbc8fd4ac3ddc66319ec55f1b8ec9f13p@chr2:119726719..119726744, +
2.11e-101FFCP PHASE1:Hg19::chr2:119726719..119726744,+#_dbc8fd4ac3ddc66319ec55f1b8ec9f13p@chr2:119726719..119726744, +
6.02e-101FFCP PHASE1:Hg19::chr10:73648356..73648408,-#_5ec94b6bb82431e45a3d80174933669ep@chr10:73648356..73648408, -
6.02e-101FFCP PHASE2:Hg19::chr10:73648356..73648408,-#_5ec94b6bb82431e45a3d80174933669ep@chr10:73648356..73648408, -
7.24e-101FFCP PHASE1:Hg19::chr4:185314151..185314178,-#_e3fa43a7157d560a401f9d82edfb1695p@chr4:185314151..185314178, -
7.24e-101FFCP PHASE2:Hg19::chr4:185314151..185314178,-#_e3fa43a7157d560a401f9d82edfb1695p@chr4:185314151..185314178, -
8.21e-101FFCP PHASE2:Hg19::chr19:18288064..18288080,+#_cf4fad3c0f83846e35209968edef3b93p@chr19:18288064..18288080, +
8.21e-101FFCP PHASE1:Hg19::chr19:18288064..18288080,+#_cf4fad3c0f83846e35209968edef3b93p@chr19:18288064..18288080, +
3.82e-100FFCP PHASE1:Hg19::chrX:153286067..153286101,-#_03a1bfd7d43b897cb5fbbbbd9661ffdcp@chrX:153286067..153286101, -
3.82e-100FFCP PHASE2:Hg19::chrX:153286067..153286101,-#_03a1bfd7d43b897cb5fbbbbd9661ffdcp@chrX:153286067..153286101, -
4.64e-100FFCP PHASE2:Hg19::chr4:185314188..185314207,-#_c6bd6d4e94f4e2f7729de93bcc41c515p@chr4:185314188..185314207, -
4.64e-100FFCP PHASE1:Hg19::chr4:185314188..185314207,-#_c6bd6d4e94f4e2f7729de93bcc41c515p@chr4:185314188..185314207, -
7.34e-100FFCP PHASE1:Hg19::chrX:37664331..37664352,+#_57f4cdc1a6cd84f45f77e50503072795p@chrX:37664331..37664352, +
7.34e-100FFCP PHASE2:Hg19::chrX:37664331..37664352,+#_57f4cdc1a6cd84f45f77e50503072795p@chrX:37664331..37664352, +
1.26e-99FFCP PHASE1:Hg19::chr1:150724282..150724308,-#_055516f08a1e8e4aa32e040230133b0dp8@CTSS
1.26e-99FFCP PHASE2:Hg19::chr1:150724282..150724308,-#_055516f08a1e8e4aa32e040230133b0dp8@CTSS
1.49e-99FFCP PHASE2:Hg19::chr1:161188826..161188842,+#_a5a92d3282e357a6cf89b988635d70bap@chr1:161188826..161188842, +
1.49e-99FFCP PHASE2:Hg19::chr2:145276939..145276960,+#_a5a92d3282e357a6cf89b988635d70bap2@ZEB2-AS1
1.49e-99FFCP PHASE1:Hg19::chr2:145276939..145276960,+#_a5a92d3282e357a6cf89b988635d70bap2@ZEB2-AS1
1.49e-99FFCP PHASE1:Hg19::chr1:161188826..161188842,+#_a5a92d3282e357a6cf89b988635d70bap@chr1:161188826..161188842, +
2.41e-99FFCP PHASE2:Hg19::chr8:116588888..116588904,+#_2c5ba577e02efe5816e70bac70a99fbap@chr8:116588888..116588904, +
2.41e-99FFCP PHASE1:Hg19::chr8:116588888..116588904,+#_2c5ba577e02efe5816e70bac70a99fbap@chr8:116588888..116588904, +
3.12e-99FFCP PHASE2:Hg19::chr1:145610717..145610730,+#_0ab46bde54cfc4ce5c8bf28d85cd4756p4@RNF115
3.12e-99FFCP PHASE1:Hg19::chr1:145610717..145610730,+#_0ab46bde54cfc4ce5c8bf28d85cd4756p4@RNF115
6.31e-99FFCP PHASE1:Hg19::chr19:18285955..18285972,+#_140e54e20c44befb3ff954848a52272bp@chr19:18285955..18285972, +
6.31e-99FFCP PHASE2:Hg19::chr19:18285955..18285972,+#_140e54e20c44befb3ff954848a52272bp@chr19:18285955..18285972, +
6.91e-99FFCP PHASE2:Hg19::chr2:129283966..129283970,+#_d97a175e30bb7bf19a262cc3252ee96cp@chr2:129283966..129283970, +
6.91e-99FFCP PHASE1:Hg19::chr2:129283966..129283970,+#_d97a175e30bb7bf19a262cc3252ee96cp@chr2:129283966..129283970, +
1.67e-98FFCP PHASE1:Hg19::chr1:26602990..26603008,+#_5a97f2199be8cbab7d998771cec7d267p@chr1:26602990..26603008, +
1.67e-98FFCP PHASE2:Hg19::chr1:26602990..26603008,+#_5a97f2199be8cbab7d998771cec7d267p@chr1:26602990..26603008, +
1.95e-98FFCP PHASE2:Hg19::chr1:108593061..108593077,+#_7efb429297c773ee1bacd6bd91a50feap@chr1:108593061..108593077, +
1.95e-98FFCP PHASE1:Hg19::chr1:108593061..108593077,+#_7efb429297c773ee1bacd6bd91a50feap@chr1:108593061..108593077, +
2.14e-98FFCP PHASE1:Hg19::chr19:18288914..18288931,-#_68820a8b835e7042b19099f3ade35078p5@CU676849, p5@CU689079
2.14e-98FFCP PHASE2:Hg19::chr19:18288914..18288931,-#_68820a8b835e7042b19099f3ade35078p5@CU676849, p5@CU689079
2.9e-98FFCP PHASE2:Hg19::chr20:1517991..1518011,-#_6e836f25f30cbd565f1b8d1c01d2fb1ep@chr20:1517991..1518011, -
2.9e-98FFCP PHASE1:Hg19::chr20:1517991..1518011,-#_6e836f25f30cbd565f1b8d1c01d2fb1ep@chr20:1517991..1518011, -
5.04e-98FFCP PHASE2:Hg19::chr19:18283959..18283993,+#_ee27b2938749d19386fd16683bc24e4bp@chr19:18283959..18283993, +
5.04e-98FFCP PHASE1:Hg19::chr19:18283959..18283993,+#_ee27b2938749d19386fd16683bc24e4bp@chr19:18283959..18283993, +
1.42e-97FFCP PHASE1:Hg19::chr19:18288514..18288554,+#_78e2402cbac4cff40b9afff0ae776073p6@IFI30
1.42e-97FFCP PHASE2:Hg19::chr19:18288514..18288554,+#_78e2402cbac4cff40b9afff0ae776073p6@IFI30
1.8e-97FFCP PHASE2:Hg19::chr5:180242576..180242585,-#_3a6ebe3e9d7da1bd59c8c0e104545391p12@MGAT1
1.8e-97FFCP PHASE1:Hg19::chr5:180242576..180242585,-#_3a6ebe3e9d7da1bd59c8c0e104545391p12@MGAT1
3.13e-97FFCP PHASE2:Hg19::chr8:53373491..53373506,-#_21c3a637a76eb46823f602b6f207d3a6p4@ST18
3.13e-97FFCP PHASE1:Hg19::chr8:53373491..53373506,-#_21c3a637a76eb46823f602b6f207d3a6p4@ST18
4.98e-97FFCP PHASE1:Hg19::chr7:6066589..6066602,-#_07a3dde7adcb3a69e4b98aa8a6cc758cp4@EIF2AK1
4.98e-97FFCP PHASE2:Hg19::chr7:6066589..6066602,-#_07a3dde7adcb3a69e4b98aa8a6cc758cp4@EIF2AK1
6.22e-97FFCP PHASE2:Hg19::chr17:7483714..7483726,+#_6449b142b2152f554c25e3f79a6c5491p@chr17:7483714..7483726, +
6.22e-97FFCP PHASE1:Hg19::chr17:7483714..7483726,+#_6449b142b2152f554c25e3f79a6c5491p@chr17:7483714..7483726, +
7.99e-97FFCP PHASE1:Hg19::chr7:128503395..128503414,+#_66a8556a0aed7d6b48946b1d4df7ad5fp@chr7:128503395..128503414, +
7.99e-97FFCP PHASE2:Hg19::chr7:128503395..128503414,+#_66a8556a0aed7d6b48946b1d4df7ad5fp@chr7:128503395..128503414, +