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Coexpression cluster:C117

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Full id: C117_serous_clear_kidney_neuroectodermal_mesothelioma_endometrial_Intestinal



Phase1 CAGE Peaks

Hg19::chr10:3305882..3305893,+p@chr10:3305882..3305893
+
Hg19::chr10:85857839..85857840,-p@chr10:85857839..85857840
-
Hg19::chr10:85931768..85931785,-p4@ENST00000514797
p4@uc001kct.2
Hg19::chr10:85931846..85931867,-p1@ENST00000514797
p1@uc001kct.2
Hg19::chr10:96731879..96731924,+p@chr10:96731879..96731924
+
Hg19::chr11:11833036..11833048,-p@chr11:11833036..11833048
-
Hg19::chr11:89223721..89223728,-p@chr11:89223721..89223728
-
Hg19::chr12:123070114..123070123,+p@chr12:123070114..123070123
+
Hg19::chr12:132680939..132680977,+p@chr12:132680939..132680977
+
Hg19::chr12:132681008..132681011,+p@chr12:132681008..132681011
+
Hg19::chr12:132681018..132681026,+p@chr12:132681018..132681026
+
Hg19::chr12:132681039..132681046,+p@chr12:132681039..132681046
+
Hg19::chr12:132681059..132681070,+p@chr12:132681059..132681070
+
Hg19::chr12:31652588..31652610,-p@chr12:31652588..31652610
-
Hg19::chr12:39104065..39104071,-p@chr12:39104065..39104071
-
Hg19::chr13:23467567..23467577,+p@chr13:23467567..23467577
+
Hg19::chr13:23479449..23479452,+p@chr13:23479449..23479452
+
Hg19::chr13:23486051..23486062,+p@chr13:23486051..23486062
+
Hg19::chr14:64405176..64405183,+p@chr14:64405176..64405183
+
Hg19::chr15:75397998..75398004,-p@chr15:75397998..75398004
-
Hg19::chr16:2106134..2106163,+p18@TSC2
Hg19::chr16:831621..831649,+p@chr16:831621..831649
+
Hg19::chr17:36003553..36003559,-p6@DDX52
Hg19::chr17:36068486..36068493,+p@chr17:36068486..36068493
+
Hg19::chr17:73554365..73554374,+p@chr17:73554365..73554374
+
Hg19::chr17:74128596..74128610,-p@chr17:74128596..74128610
-
Hg19::chr17:74134377..74134388,-p@chr17:74134377..74134388
-
Hg19::chr18:11959017..11959052,+p@chr18:11959017..11959052
+
Hg19::chr18:52274330..52274344,-p@chr18:52274330..52274344
-
Hg19::chr18:69246146..69246156,-p3@LOC100505776
Hg19::chr18:69246167..69246179,-p2@LOC100505776
Hg19::chr18:69246186..69246197,-p1@LOC100505776
Hg19::chr18:6982576..6982589,-p@chr18:6982576..6982589
-
Hg19::chr19:40697978..40698010,+p6@MAP3K10
Hg19::chr19:40762956..40762973,-p@chr19:40762956..40762973
-
Hg19::chr1:205601064..205601087,-p4@ELK4
Hg19::chr1:214650069..214650072,-p@chr1:214650069..214650072
-
Hg19::chr1:214650077..214650084,-p@chr1:214650077..214650084
-
Hg19::chr1:214650108..214650118,-p@chr1:214650108..214650118
-
Hg19::chr1:215257098..215257110,+p@chr1:215257098..215257110
+
Hg19::chr1:215257112..215257119,+p@chr1:215257112..215257119
+
Hg19::chr1:224370589..224370611,+p3@DEGS1
Hg19::chr1:46787487..46787492,-p@chr1:46787487..46787492
-
Hg19::chr1:46797583..46797614,-p@chr1:46797583..46797614
-
Hg19::chr1:94780142..94780153,-p@chr1:94780142..94780153
-
Hg19::chr1:94780176..94780187,-p@chr1:94780176..94780187
-
Hg19::chr20:15866720..15866725,-p@chr20:15866720..15866725
-
Hg19::chr20:15871874..15871910,-p@chr20:15871874..15871910
-
Hg19::chr20:15872559..15872568,-p@chr20:15872559..15872568
-
Hg19::chr20:15873011..15873014,-p@chr20:15873011..15873014
-
Hg19::chr20:15878694..15878728,-p@chr20:15878694..15878728
-
Hg19::chr20:15879525..15879530,-p@chr20:15879525..15879530
-
Hg19::chr20:15891295..15891297,-p@chr20:15891295..15891297
-
Hg19::chr20:15896547..15896555,-p@chr20:15896547..15896555
-
Hg19::chr20:15896790..15896803,-p@chr20:15896790..15896803
-
Hg19::chr20:15898490..15898493,-p@chr20:15898490..15898493
-
Hg19::chr20:15916678..15916682,-p@chr20:15916678..15916682
-
Hg19::chr20:15942024..15942025,-p@chr20:15942024..15942025
-
Hg19::chr20:15948322..15948327,-p@chr20:15948322..15948327
-
Hg19::chr20:15954227..15954237,-p@chr20:15954227..15954237
-
Hg19::chr20:15966439..15966448,-p@chr20:15966439..15966448
-
Hg19::chr20:15967531..15967544,+p@chr20:15967531..15967544
+
Hg19::chr20:15967629..15967655,+p@chr20:15967629..15967655
+
Hg19::chr20:15967658..15967661,+p@chr20:15967658..15967661
+
Hg19::chr20:15967691..15967705,+p@chr20:15967691..15967705
+
Hg19::chr20:58319374..58319386,-p@chr20:58319374..58319386
-
Hg19::chr20:60934189..60934206,-p@chr20:60934189..60934206
-
Hg19::chr20:60934239..60934260,-p@chr20:60934239..60934260
-
Hg19::chr20:62113538..62113571,-p@chr20:62113538..62113571
-
Hg19::chr21:44441260..44441273,+p3@PKNOX1
Hg19::chr22:31495739..31495756,+p33@SMTN
Hg19::chr22:31739255..31739259,-p28@PATZ1
Hg19::chr22:46812806..46812838,-p@chr22:46812806..46812838
-
Hg19::chr2:231906019..231906031,+p6@C2orf72
Hg19::chr2:239066313..239066357,+p@chr2:239066313..239066357
+
Hg19::chr2:28503793..28503800,+p@chr2:28503793..28503800
+
Hg19::chr2:31637816..31637836,-p7@XDH
Hg19::chr2:34902620..34902625,+p1@ENST00000423663
Hg19::chr2:34902895..34902908,+p1@uc002rpc.1
Hg19::chr2:34935472..34935477,+p@chr2:34935472..34935477
+
Hg19::chr2:34971950..34971953,+p@chr2:34971950..34971953
+
Hg19::chr3:168582660..168582692,+p@chr3:168582660..168582692
+
Hg19::chr3:168802151..168802153,-p@chr3:168802151..168802153
-
Hg19::chr3:168861573..168861582,-p@chr3:168861573..168861582
-
Hg19::chr3:168864427..168864464,-p19@MECOM
Hg19::chr3:168864831..168864851,-p9@MECOM
Hg19::chr3:168864936..168864953,-p8@MECOM
Hg19::chr3:168865144..168865160,-p6@MECOM
Hg19::chr3:168865250..168865272,-p5@MECOM
Hg19::chr3:168865278..168865292,-p14@MECOM
Hg19::chr3:168865323..168865337,-p15@MECOM
Hg19::chr3:168865364..168865376,-p11@MECOM
Hg19::chr3:168865497..168865516,-p16@MECOM
Hg19::chr4:135331403..135331405,-p@chr4:135331403..135331405
-
Hg19::chr4:135507221..135507238,-p@chr4:135507221..135507238
-
Hg19::chr4:159430869..159430885,-p1@ENST00000502566
Hg19::chr4:159442958..159442977,+p4@RXFP1
Hg19::chr4:159443003..159443018,+p3@RXFP1
Hg19::chr4:159443024..159443056,+p1@RXFP1
Hg19::chr4:159446395..159446403,+p@chr4:159446395..159446403
+
Hg19::chr4:159541085..159541093,+p@chr4:159541085..159541093
+
Hg19::chr4:175184004..175184014,-p16@FBXO8
Hg19::chr4:175184030..175184041,-p13@FBXO8
Hg19::chr4:175184051..175184061,-p18@FBXO8
Hg19::chr4:175184162..175184175,-p9@FBXO8
Hg19::chr4:175184180..175184194,-p2@FBXO8
Hg19::chr4:175184203..175184220,-p6@FBXO8
Hg19::chr4:175184241..175184250,-p14@FBXO8
Hg19::chr4:175204717..175204728,-p17@FBXO8
Hg19::chr4:25649638..25649642,+p@chr4:25649638..25649642
+
Hg19::chr5:175799252..175799262,-p@chr5:175799252..175799262
-
Hg19::chr5:31936363..31936370,+p19@PDZD2
Hg19::chr5:31936389..31936400,+p11@PDZD2
Hg19::chr5:36105527..36105539,-p@chr5:36105527..36105539
-
Hg19::chr6:137844183..137844191,-p@chr6:137844183..137844191
-
Hg19::chr6:13925318..13925342,+p2@RNF182
Hg19::chr6:14049473..14049508,+p@chr6:14049473..14049508
+
Hg19::chr6:24323980..24323989,-p@chr6:24323980..24323989
-
Hg19::chr6:47602833..47602848,+p@chr6:47602833..47602848
+
Hg19::chr6:64025774..64025778,-p@chr6:64025774..64025778
-
Hg19::chr6:64043904..64043907,-p@chr6:64043904..64043907
-
Hg19::chr6:64049378..64049403,-p@chr6:64049378..64049403
-
Hg19::chr6:64050722..64050726,-p@chr6:64050722..64050726
-
Hg19::chr6:64145806..64145815,-p@chr6:64145806..64145815
-
Hg19::chr6:64151611..64151636,-p@chr6:64151611..64151636
-
Hg19::chr6:64152250..64152255,-p@chr6:64152250..64152255
-
Hg19::chr6:72241518..72241524,+p@chr6:72241518..72241524
+
Hg19::chr6:75233360..75233363,+p@chr6:75233360..75233363
+
Hg19::chr7:107643719..107643730,-p9@LAMB1
Hg19::chr7:107644847..107644884,-p@chr7:107644847..107644884
-
Hg19::chr7:107707064..107707079,-p@chr7:107707064..107707079
-
Hg19::chr7:107707083..107707099,-p@chr7:107707083..107707099
-
Hg19::chr7:134627808..134627842,+p@chr7:134627808..134627842
+
Hg19::chr7:138816862..138816869,-p@chr7:138816862..138816869
-
Hg19::chr7:151791137..151791153,+p3@GALNT11
Hg19::chr7:151791485..151791495,+p15@GALNT11
Hg19::chr7:98735181..98735195,-p@chr7:98735181..98735195
-
Hg19::chr7:98735218..98735228,-p@chr7:98735218..98735228
-
Hg19::chr7:98735238..98735250,-p@chr7:98735238..98735250
-
Hg19::chr8:101363016..101363029,+p@chr8:101363016..101363029
+
Hg19::chr8:142247795..142247863,-p@chr8:142247795..142247863
-
Hg19::chr8:142247940..142247948,-p@chr8:142247940..142247948
-
Hg19::chr8:144124493..144124500,+p8@C8orf31
Hg19::chr8:144124531..144124572,+p2@C8orf31
Hg19::chr8:20070210..20070250,+p@chr8:20070210..20070250
+
Hg19::chr9:132472174..132472192,+p@chr9:132472174..132472192
+
Hg19::chr9:136856204..136856219,+p@chr9:136856204..136856219
+
Hg19::chr9:138466794..138466798,+p1@ENST00000445997
Hg19::chr9:90000420..90000454,-p@chr9:90000420..90000454
-
Hg19::chr9:90680465..90680480,-p1@uc004apv.1
Hg19::chrX:16329834..16329838,-p@chrX:16329834..16329838
-
Hg19::chrX:16422567..16422570,-p@chrX:16422567..16422570
-
Hg19::chrX:16530591..16530601,-p@chrX:16530591..16530601
-
Hg19::chrX:16530614..16530628,-p@chrX:16530614..16530628
-
Hg19::chrX:35711783..35711785,+p@chrX:35711783..35711785
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0005515protein binding0.0291416460614624
GO:0004855xanthine oxidase activity0.0291416460614624
GO:0043257laminin-8 complex0.0291416460614624
GO:0005607laminin-2 complex0.0291416460614624
GO:0016727oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor0.0291416460614624
GO:0016726oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor0.0364195514862496
GO:0004854xanthine dehydrogenase activity0.0364195514862496
GO:0043259laminin-10 complex0.0364195514862496
GO:0050794regulation of cellular process0.0436944567728137
GO:0004706JUN kinase kinase kinase activity0.0436944567728137
GO:0033559unsaturated fatty acid metabolic process0.0477161790289686
GO:0006636unsaturated fatty acid biosynthetic process0.0477161790289686
GO:0044424intracellular part0.0477161790289686
GO:0050789regulation of biological process0.0477161790289686
GO:0042803protein homodimerization activity0.0477161790289686



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br>disease_data<br>


Uber Anatomy
Ontology termp-valuen
anatomical conduit1.45e-16241
tube1.97e-16194
adult organism2.59e-16115
anatomical cluster2.80e-16286
organ1.61e-10511
epithelium1.84e-10309
anterior neural tube2.68e-1042
telencephalon3.30e-1034
cerebral hemisphere3.65e-1032
gray matter4.12e-1034
brain grey matter4.12e-1034
multi-tissue structure4.36e-10347
neural tube4.58e-1057
neural rod4.58e-1057
future spinal cord4.58e-1057
neural keel4.58e-1057
regional part of forebrain4.85e-1041
forebrain4.85e-1041
future forebrain4.85e-1041
organ part7.92e-10219
regional part of telencephalon7.98e-1033
cell layer1.28e-09312
regional part of cerebral cortex3.05e-0922
abdomen element3.05e-0955
abdominal segment element3.05e-0955
anatomical group3.26e-09626
neocortex4.87e-0920
anatomical system5.84e-09625
cerebral cortex1.62e-0825
pallium1.62e-0825
trunk region element1.97e-08107
body cavity precursor2.40e-0863
cavitated compound organ3.56e-0832
immaterial anatomical entity3.92e-08126
neural plate3.93e-0886
presumptive neural plate3.93e-0886
multi-cellular organism4.99e-08659
anatomical cavity5.34e-0870
regional part of brain5.86e-0859
abdominal segment of trunk6.53e-0861
abdomen6.53e-0861
central nervous system9.11e-0882
neurectoderm1.64e-0790
kidney1.75e-0727
kidney mesenchyme1.75e-0727
kidney rudiment1.75e-0727
kidney field1.75e-0727
brain2.17e-0769
future brain2.17e-0769
intraembryonic coelom2.17e-0721
subdivision of digestive tract4.11e-07129
endodermal part of digestive tract4.11e-07129
compound organ4.72e-0769
regional part of nervous system5.56e-0794
nervous system5.56e-0794
epithelial tube5.83e-07118
organism subdivision6.05e-07365
renal system8.24e-0745
Disease
Ontology termp-valuen
carcinoma4.54e-10106
cell type cancer5.19e-09143


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


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