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Coexpression cluster:C120

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Full id: C120_immature_salivary_tongue_skin_cervical_CD14_CD34



Phase1 CAGE Peaks

  Short description
Hg19::chr10:103893775..103893800,- p@chr10:103893775..103893800
-
Hg19::chr10:135337169..135337187,- p@chr10:135337169..135337187
-
Hg19::chr10:135337234..135337244,- p@chr10:135337234..135337244
-
Hg19::chr10:135337292..135337307,- p@chr10:135337292..135337307
-
Hg19::chr10:81701830..81701837,- p@chr10:81701830..81701837
-
Hg19::chr10:85954269..85954280,+ p4@CDHR1
Hg19::chr10:85954282..85954314,+ p1@CDHR1
Hg19::chr10:97592419..97592428,+ p@chr10:97592419..97592428
+
Hg19::chr11:108408895..108408924,- p3@EXPH5
Hg19::chr11:113258495..113258506,+ p1@ANKK1
Hg19::chr11:12214399..12214404,- p@chr11:12214399..12214404
-
Hg19::chr11:12214548..12214586,+ p@chr11:12214548..12214586
+
Hg19::chr11:57543275..57543296,+ p@chr11:57543275..57543296
+
Hg19::chr11:62311004..62311025,+ p@chr11:62311004..62311025
+
Hg19::chr11:65363259..65363275,- p1@KCNK7
Hg19::chr12:112587704..112587710,+ p@chr12:112587704..112587710
+
Hg19::chr12:322653..322665,- p8@SLC6A12
Hg19::chr12:52541319..52541358,+ p@chr12:52541319..52541358
+
Hg19::chr12:53045991..53045996,- p1@KRT2
Hg19::chr12:53268328..53268340,+ p@chr12:53268328..53268340
+
Hg19::chr13:23490561..23490568,- p1@ENST00000379093
Hg19::chr13:78130718..78130733,+ p@chr13:78130718..78130733
+
Hg19::chr13:79979347..79979384,+ p@chr13:79979347..79979384
+
Hg19::chr14:104583456..104583460,+ p1@MIR203
Hg19::chr14:24017647..24017657,- p15@ZFHX2
Hg19::chr14:50234166..50234170,+ p6@KLHDC2
Hg19::chr14:67879076..67879080,+ p@chr14:67879076..67879080
+
Hg19::chr14:69192856..69192867,- p@chr14:69192856..69192867
-
Hg19::chr14:69223811..69223817,+ p@chr14:69223811..69223817
+
Hg19::chr14:94833955..94833966,+ p@chr14:94833955..94833966
+
Hg19::chr15:42313237..42313242,- p@chr15:42313237..42313242
-
Hg19::chr15:42448788..42448849,- p1@PLA2G4F
Hg19::chr15:59949497..59949508,- p3@GTF2A2
Hg19::chr16:10915414..10915421,+ p@chr16:10915414..10915421
+
Hg19::chr16:10953616..10953637,+ p@chr16:10953616..10953637
+
Hg19::chr16:10970721..10970727,- p@chr16:10970721..10970727
-
Hg19::chr16:1257038..1257050,+ p@chr16:1257038..1257050
+
Hg19::chr16:31454377..31454381,+ p@chr16:31454377..31454381
+
Hg19::chr16:33722353..33722359,+ p@chr16:33722353..33722359
+
Hg19::chr16:34571309..34571314,- p@chr16:34571309..34571314
-
Hg19::chr16:75018508..75018512,+ p@chr16:75018508..75018512
+
Hg19::chr16:85894104..85894112,- p@chr16:85894104..85894112
-
Hg19::chr17:10009524..10009534,- p@chr17:10009524..10009534
-
Hg19::chr17:10009535..10009542,- p@chr17:10009535..10009542
-
Hg19::chr17:25874072..25874076,+ p@chr17:25874072..25874076
+
Hg19::chr17:29887192..29887207,- p@chr17:29887192..29887207
-
Hg19::chr17:39812242..39812247,+ p@chr17:39812242..39812247
+
Hg19::chr17:48546232..48546247,- p1@CHAD
Hg19::chr17:7154246..7154280,+ p@chr17:7154246..7154280
+
Hg19::chr17:7183607..7183612,- p@chr17:7183607..7183612
-
Hg19::chr17:7819599..7819609,- p1@ENST00000324348
Hg19::chr17:79874727..79874731,+ p@chr17:79874727..79874731
+
Hg19::chr18:13562948..13562955,+ p@chr18:13562948..13562955
+
Hg19::chr18:23806437..23806449,+ p2@TAF4B
Hg19::chr18:53545728..53545733,+ p@chr18:53545728..53545733
+
Hg19::chr18:53548086..53548099,- p@chr18:53548086..53548099
-
Hg19::chr19:10024468..10024484,- p@chr19:10024468..10024484
-
Hg19::chr19:1180737..1180757,+ p@chr19:1180737..1180757
+
Hg19::chr19:1180760..1180775,+ p@chr19:1180760..1180775
+
Hg19::chr19:1180783..1180800,+ p@chr19:1180783..1180800
+
Hg19::chr19:2090131..2090140,- p@chr19:2090131..2090140
-
Hg19::chr19:33783896..33783902,+ p@chr19:33783896..33783902
+
Hg19::chr19:35481293..35481296,- p@chr19:35481293..35481296
-
Hg19::chr19:40440897..40440908,- p2@FCGBP
Hg19::chr19:55581103..55581143,- p4@RDH13
Hg19::chr19:6062602..6062619,+ p@chr19:6062602..6062619
+
Hg19::chr19:6063658..6063670,- p@chr19:6063658..6063670
-
Hg19::chr19:6063965..6063994,+ p@chr19:6063965..6063994
+
Hg19::chr19:9732460..9732472,- p2@ZNF561
Hg19::chr1:1100457..1100470,+ p@chr1:1100457..1100470
+
Hg19::chr1:117602977..117602984,+ p3@TTF2
Hg19::chr1:11865532..11865537,- p11@MTHFR
Hg19::chr1:152878978..152878994,+ p@chr1:152878978..152878994
+
Hg19::chr1:157926828..157926838,+ p@chr1:157926828..157926838
+
Hg19::chr1:158224235..158224244,+ p10@CD1A
Hg19::chr1:16481684..16481727,+ p1@ENST00000424774
Hg19::chr1:183442112..183442126,- p@chr1:183442112..183442126
-
Hg19::chr1:19283116..19283132,- p1@IFFO2
Hg19::chr1:19283143..19283154,- p3@IFFO2
Hg19::chr1:212780312..212780339,+ p@chr1:212780312..212780339
+
Hg19::chr1:212780356..212780372,+ p@chr1:212780356..212780372
+
Hg19::chr1:27181551..27181558,- p@chr1:27181551..27181558
-
Hg19::chr1:29270212..29270216,- p@chr1:29270212..29270216
-
Hg19::chr1:39571788..39571799,- p@chr1:39571788..39571799
-
Hg19::chr1:42902892..42902896,+ p@chr1:42902892..42902896
+
Hg19::chr1:85462278..85462283,+ p@chr1:85462278..85462283
+
Hg19::chr20:1762918..1762921,- p@chr20:1762918..1762921
-
Hg19::chr20:19095317..19095322,+ p@chr20:19095317..19095322
+
Hg19::chr20:23117745..23117783,+ p@chr20:23117745..23117783
+
Hg19::chr20:24933916..24933922,- p@chr20:24933916..24933922
-
Hg19::chr20:43588041..43588075,+ p@chr20:43588041..43588075
+
Hg19::chr20:44639343..44639375,+ p@chr20:44639343..44639375
+
Hg19::chr20:44639385..44639400,+ p@chr20:44639385..44639400
+
Hg19::chr2:122041216..122041223,- p@chr2:122041216..122041223
-
Hg19::chr2:173867941..173867955,+ p@chr2:173867941..173867955
+
Hg19::chr2:208368220..208368233,+ p@chr2:208368220..208368233
+
Hg19::chr2:216002151..216002158,+ p@chr2:216002151..216002158
+
Hg19::chr2:216003243..216003282,- p2@ABCA12
Hg19::chr2:216003447..216003472,+ p@chr2:216003447..216003472
+
Hg19::chr2:230990020..230990046,+ p1@ENST00000445199
Hg19::chr2:38948032..38948038,- p@chr2:38948032..38948038
-
Hg19::chr2:64587249..64587257,- p@chr2:64587249..64587257
-
Hg19::chr2:64680581..64680593,+ +
p@chr2:64680581..64680593
Hg19::chr2:64680611..64680624,+ p11@LGALSL
Hg19::chr2:71057780..71057794,- p@chr2:71057780..71057794
-
Hg19::chr2:71057873..71057874,- p@chr2:71057873..71057874
-
Hg19::chr2:71058922..71058927,- p@chr2:71058922..71058927
-
Hg19::chr2:73340735..73340740,- p@chr2:73340735..73340740
-
Hg19::chr3:186252359..186252380,+ p@chr3:186252359..186252380
+
Hg19::chr3:52099097..52099134,- p1@C3orf74
Hg19::chr3:71080443..71080455,- p@chr3:71080443..71080455
-
Hg19::chr3:71080630..71080635,+ p@chr3:71080630..71080635
+
Hg19::chr4:100484667..100484671,- p8@RG9MTD2
Hg19::chr4:106817137..106817150,- p4@INTS12
Hg19::chr4:108745881..108745897,+ p4@SGMS2
Hg19::chr4:159149804..159149824,- p@chr4:159149804..159149824
-
Hg19::chr4:3392220..3392256,+ p@chr4:3392220..3392256
+
Hg19::chr5:133773054..133773060,+ p@chr5:133773054..133773060
+
Hg19::chr5:159933217..159933221,- p@chr5:159933217..159933221
-
Hg19::chr5:79551098..79551103,+ p@chr5:79551098..79551103
+
Hg19::chr6:10413321..10413336,+ p@chr6:10413321..10413336
+
Hg19::chr6:10413345..10413356,+ p@chr6:10413345..10413356
+
Hg19::chr6:106943050..106943075,+ p@chr6:106943050..106943075
+
Hg19::chr6:122532780..122532793,+ p1@RNU1-18P
Hg19::chr6:132452229..132452234,+ p@chr6:132452229..132452234
+
Hg19::chr6:138137434..138137443,+ p@chr6:138137434..138137443
+
Hg19::chr6:32140886..32140902,- p26@AGPAT1
Hg19::chr6:32632755..32632783,- p5@HLA-DQB1
Hg19::chr6:32729494..32729506,- p1@M95729
Hg19::chr6:32729634..32729642,- p2@M95729
Hg19::chr6:36992669..36992691,+ p@chr6:36992669..36992691
+
Hg19::chr7:2284179..2284201,+ p3@NUDT1
Hg19::chr7:39767535..39767539,+ +
p@chr7:39767535..39767539
Hg19::chr7:42928540..42928555,+ p@chr7:42928540..42928555
+
Hg19::chr7:55594397..55594400,+ +
p@chr7:55594397..55594400
Hg19::chr8:144261054..144261063,- p@chr8:144261054..144261063
-
Hg19::chr8:22069222..22069228,+ p@chr8:22069222..22069228
+
Hg19::chr8:57233103..57233123,- p2@SDR16C5
Hg19::chr8:62629856..62629862,+ p@chr8:62629856..62629862
+
Hg19::chr8:987779..987786,+ p@chr8:987779..987786
+
Hg19::chr9:109626921..109626926,- p@chr9:109626921..109626926
-
Hg19::chr9:111314011..111314037,+ p@chr9:111314011..111314037
+
Hg19::chr9:134510706..134510711,- p@chr9:134510706..134510711
-
Hg19::chr9:136004782..136004793,- p23@RALGDS
Hg19::chr9:34662651..34662656,- p1@CCL27
Hg19::chr9:87445344..87445355,+ p@chr9:87445344..87445355
+
Hg19::chrX:131156808..131156816,+ p6@MST4
Hg19::chrX:135838814..135838818,+ p@chrX:135838814..135838818
+
Hg19::chrY:27869488..27869491,+ p1@ENST00000516617


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression clusterSummary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner

link to source dataset
data


GO IDGO nameFDR corrected p-value
GO:0016591DNA-directed RNA polymerase II, holoenzyme0.0331363952634676
GO:0044451nucleoplasm part0.0455375014718003
GO:0006644phospholipid metabolic process0.0455375014718003
GO:0005654nucleoplasm0.0455375014718003
GO:0032980keratinocyte activation0.0455375014718003
GO:0003717RNA polymerase II transcription termination factor activity0.0455375014718003
GO:0006643membrane lipid metabolic process0.0481807030480791
GO:00084138-oxo-7,8-dihydroguanine triphosphatase activity0.0481807030480791
GO:0033188sphingomyelin synthase activity0.0481807030480791
GO:0047493ceramide cholinephosphotransferase activity0.0481807030480791
GO:0031981nuclear lumen0.0481807030480791
GO:0006352transcription initiation0.0481807030480791
GO:0008654phospholipid biosynthetic process0.0481807030480791
GO:0004489methylenetetrahydrofolate reductase (NADPH) activity0.0481807030480791
GO:0006654phosphatidic acid biosynthetic process0.0481807030480791
GO:0051546keratinocyte migration0.0481807030480791
GO:0006686sphingomyelin biosynthetic process0.0481807030480791



Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset

cell_data
uberon_data
disease_data


Cell Type
Ontology termp-valuen
CD14-positive, CD16-negative classical monocyte5.51e-2242
classical monocyte4.41e-2145
leukocyte1.47e-15140
myeloid leukocyte1.72e-1576
macrophage dendritic cell progenitor1.53e-1465
granulocyte monocyte progenitor cell2.56e-1471
monopoietic cell2.00e-1363
monocyte2.00e-1363
monoblast2.00e-1363
promonocyte2.00e-1363
myeloid lineage restricted progenitor cell1.32e-1170
nongranular leukocyte3.40e-11119
hematopoietic lineage restricted progenitor cell1.95e-10124
endo-epithelial cell2.15e-0943
hematopoietic stem cell4.91e-09172
angioblastic mesenchymal cell4.91e-09172
myeloid cell2.23e-08112
common myeloid progenitor2.23e-08112
hematopoietic cell4.92e-08182
hematopoietic oligopotent progenitor cell7.90e-08165
hematopoietic multipotent progenitor cell7.90e-08165
epithelial cell1.38e-07254
Uber Anatomy
Ontology termp-valuen
hematopoietic system3.85e-11102
blood island3.85e-11102
bone marrow6.61e-1180
hemolymphoid system2.03e-09112
bone element2.07e-0986
adult organism4.41e-08115
organ2.96e-07511
respiratory system6.86e-0772
Disease
Ontology termp-valuen
carcinoma1.88e-07106
squamous cell carcinoma7.60e-0714


Overrepresented TFBS (DNA) motifs on this co-expression clusterSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysisSummary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner

link to source dataset

data


(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
GATA3#2625122.193544941519950.009168760899619630.0346822245416651



Relative expression of the co-expression clusterSummary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.
Analyst:NA

link to data source
data