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{{Coexpression_clusters
{{Coexpression_clusters
|full_id=C1357_Mesenchymal_Alveolar_Renal_Placental_acantholytic_Tracheal_Bronchial
|full_id=C1357_Mesenchymal_Alveolar_Renal_Placental_acantholytic_Tracheal_Bronchial
|gostat_on_coexpression_clusters=GO:0007199!G-protein signaling, coupled to cGMP nucleotide second messenger!0.011538404895764!10607$GO:0019934!cGMP-mediated signaling!0.011538404895764!10607$GO:0006357!regulation of transcription from RNA polymerase II promoter!0.0172999664284364!10155;6895$GO:0030515!snoRNA binding!0.0172999664284364!79050$GO:0005634!nucleus!0.0172999664284364!10155;10607;79050;6895$GO:0043193!positive regulation of gene-specific transcription!0.0172999664284364!10155$GO:0001837!epithelial to mesenchymal transition!0.0172999664284364!10155$GO:0032583!regulation of gene-specific transcription!0.0172999664284364!10155$GO:0005732!small nucleolar ribonucleoprotein complex!0.0192196385985799!79050$GO:0006366!transcription from RNA polymerase II promoter!0.0203185721744452!10155;6895$GO:0048762!mesenchymal cell differentiation!0.0230544017185297!10155$GO:0014031!mesenchymal cell development!0.0230544017185297!10155$GO:0043231!intracellular membrane-bound organelle!0.0295162839166376!10155;10607;79050;6895$GO:0043227!membrane-bound organelle!0.0295162839166376!10155;10607;79050;6895$GO:0003723!RNA binding!0.0295162839166376!79050;6895$GO:0044452!nucleolar part!0.0295162839166376!79050$GO:0003725!double-stranded RNA binding!0.0358917455404646!6895
|id=C1357
|id=C1357
}}
}}

Revision as of 17:34, 18 May 2012


Full id: C1357_Mesenchymal_Alveolar_Renal_Placental_acantholytic_Tracheal_Bronchial



Phase1 CAGE Peaks

Hg19::chr12:132628963..132629027,+p1@NOC4L
Hg19::chr12:53895052..53895143,+p1@TARBP2
Hg19::chr16:2022036..2022112,+p1@TBL3
Hg19::chr16:88772866..88772947,+p1@CTU2
Hg19::chr19:59055814..59055835,+p1@TRIM28
Hg19::chr19:984313..984357,+p1@WDR18


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0007199G-protein signaling, coupled to cGMP nucleotide second messenger0.011538404895764
GO:0019934cGMP-mediated signaling0.011538404895764
GO:0006357regulation of transcription from RNA polymerase II promoter0.0172999664284364
GO:0030515snoRNA binding0.0172999664284364
GO:0005634nucleus0.0172999664284364
GO:0043193positive regulation of gene-specific transcription0.0172999664284364
GO:0001837epithelial to mesenchymal transition0.0172999664284364
GO:0032583regulation of gene-specific transcription0.0172999664284364
GO:0005732small nucleolar ribonucleoprotein complex0.0192196385985799
GO:0006366transcription from RNA polymerase II promoter0.0203185721744452
GO:0048762mesenchymal cell differentiation0.0230544017185297
GO:0014031mesenchymal cell development0.0230544017185297
GO:0043231intracellular membrane-bound organelle0.0295162839166376
GO:0043227membrane-bound organelle0.0295162839166376
GO:0003723RNA binding0.0295162839166376
GO:0044452nucleolar part0.0295162839166376
GO:0003725double-stranded RNA binding0.0358917455404646



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.