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Coexpression cluster:C1382

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Full id: C1382_CD14_Natural_CD8_CD4_Basophils_CD19_Neutrophils



Phase1 CAGE Peaks

  Short description
Hg19::chr13:42037742..42037760,+ p5@C13orf15
Hg19::chr17:39845542..39845569,- p@chr17:39845542..39845569
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Hg19::chr18:33077635..33077682,+ p@chr18:33077635..33077682
+
Hg19::chr1:198126705..198126726,- p@chr1:198126705..198126726
-
Hg19::chr2:128459741..128459755,- p@chr2:128459741..128459755
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Hg19::chr2:128459765..128459803,- p@chr2:128459765..128459803
-


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression clusterSummary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner

link to source dataset
data


No GOStat results

Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset

cell_data
uberon_data


Cell Type
Ontology termp-valuen
hematopoietic stem cell3.01e-39172
angioblastic mesenchymal cell3.01e-39172
hematopoietic cell1.88e-38182
leukocyte1.36e-36140
hematopoietic oligopotent progenitor cell1.52e-35165
hematopoietic multipotent progenitor cell1.52e-35165
nongranular leukocyte3.74e-32119
hematopoietic lineage restricted progenitor cell1.25e-31124
CD14-positive, CD16-negative classical monocyte1.59e-2542
classical monocyte3.38e-2545
myeloid cell1.91e-19112
common myeloid progenitor1.91e-19112
myeloid leukocyte8.98e-1876
granulocyte monocyte progenitor cell8.84e-1771
macrophage dendritic cell progenitor3.65e-1665
myeloid lineage restricted progenitor cell2.58e-1570
lymphocyte2.91e-1553
common lymphoid progenitor2.91e-1553
monopoietic cell3.15e-1563
monocyte3.15e-1563
monoblast3.15e-1563
promonocyte3.15e-1563
lymphoid lineage restricted progenitor cell3.42e-1552
mature alpha-beta T cell3.20e-1018
alpha-beta T cell3.20e-1018
immature T cell3.20e-1018
mature T cell3.20e-1018
immature alpha-beta T cell3.20e-1018
T cell5.99e-0925
pro-T cell5.99e-0925
mesenchymal cell1.63e-08358
connective tissue cell4.42e-08365
native cell5.19e-08722
B cell4.02e-0714
Uber Anatomy
Ontology termp-valuen
hematopoietic system2.64e-18102
blood island2.64e-18102
hemolymphoid system1.31e-17112
immune system1.41e-14115
bone marrow4.97e-1480
bone element9.32e-1286
lateral plate mesoderm7.91e-09216
skeletal element4.10e-08101
skeletal system4.10e-08101
connective tissue8.28e-07375


Overrepresented TFBS (DNA) motifs on this co-expression clusterSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysisSummary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner

link to source dataset

data


No analysis results for this cluster

Relative expression of the co-expression clusterSummary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.
Analyst:NA

link to data source
data


This analysis result is provided for C0 - C305 clusters.