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{{Coexpression_clusters
{{Coexpression_clusters
|full_id=C1580_acute_Neutrophils_Mallassezderived_migratory_Smooth_Preadipocyte_small
|full_id=C1580_acute_Neutrophils_Mallassezderived_migratory_Smooth_Preadipocyte_small
|gostat_on_coexpression_clusters=GO:0007190!adenylate cyclase activation!0.00508261705718434!10487$GO:0031281!positive regulation of cyclase activity!0.00508261705718434!10487$GO:0045762!positive regulation of adenylate cyclase activity!0.00508261705718434!10487$GO:0051349!positive regulation of lyase activity!0.00508261705718434!10487$GO:0007163!establishment and/or maintenance of cell polarity!0.00508261705718434!10487$GO:0007189!G-protein signaling, adenylate cyclase activating pathway!0.00508261705718434!10487$GO:0045761!regulation of adenylate cyclase activity!0.00508261705718434!10487$GO:0031279!regulation of cyclase activity!0.00508261705718434!10487$GO:0051339!regulation of lyase activity!0.00508261705718434!10487$GO:0007188!G-protein signaling, coupled to cAMP nucleotide second messenger!0.00861404579172152!10487$GO:0019933!cAMP-mediated signaling!0.00861404579172152!10487$GO:0007187!G-protein signaling, coupled to cyclic nucleotide second messenger!0.010221087049063!10487$GO:0019935!cyclic-nucleotide-mediated signaling!0.010221087049063!10487$GO:0043085!positive regulation of catalytic activity!0.0194591624475058!10487$GO:0019932!second-messenger-mediated signaling!0.0194591624475058!10487$GO:0003779!actin binding!0.0289225113492157!10487$GO:0032989!cellular structure morphogenesis!0.0289225113492157!10487$GO:0000902!cell morphogenesis!0.0289225113492157!10487$GO:0008092!cytoskeletal protein binding!0.03294624985282!10487$GO:0050790!regulation of catalytic activity!0.03294624985282!10487$GO:0065009!regulation of a molecular function!0.0339611230639136!10487$GO:0007010!cytoskeleton organization and biogenesis!0.0339611230639136!10487$GO:0009653!anatomical structure morphogenesis!0.0495791930950809!10487
|id=C1580
|id=C1580
}}
}}

Revision as of 17:35, 18 May 2012


Full id: C1580_acute_Neutrophils_Mallassezderived_migratory_Smooth_Preadipocyte_small



Phase1 CAGE Peaks

Hg19::chr10:44101729..44101736,-p1@CAP1P2
Hg19::chr1:40506327..40506338,+p5@CAP1
Hg19::chr1:40506344..40506355,+p3@CAP1
Hg19::chr1:40506371..40506382,+p2@CAP1
Hg19::chr1:40506393..40506453,+p1@CAP1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0007190adenylate cyclase activation0.00508261705718434
GO:0031281positive regulation of cyclase activity0.00508261705718434
GO:0045762positive regulation of adenylate cyclase activity0.00508261705718434
GO:0051349positive regulation of lyase activity0.00508261705718434
GO:0007163establishment and/or maintenance of cell polarity0.00508261705718434
GO:0007189G-protein signaling, adenylate cyclase activating pathway0.00508261705718434
GO:0045761regulation of adenylate cyclase activity0.00508261705718434
GO:0031279regulation of cyclase activity0.00508261705718434
GO:0051339regulation of lyase activity0.00508261705718434
GO:0007188G-protein signaling, coupled to cAMP nucleotide second messenger0.00861404579172152
GO:0019933cAMP-mediated signaling0.00861404579172152
GO:0007187G-protein signaling, coupled to cyclic nucleotide second messenger0.010221087049063
GO:0019935cyclic-nucleotide-mediated signaling0.010221087049063
GO:0043085positive regulation of catalytic activity0.0194591624475058
GO:0019932second-messenger-mediated signaling0.0194591624475058
GO:0003779actin binding0.0289225113492157
GO:0032989cellular structure morphogenesis0.0289225113492157
GO:0000902cell morphogenesis0.0289225113492157
GO:0008092cytoskeletal protein binding0.03294624985282
GO:0050790regulation of catalytic activity0.03294624985282
GO:0065009regulation of a molecular function0.0339611230639136
GO:0007010cytoskeleton organization and biogenesis0.0339611230639136
GO:0009653anatomical structure morphogenesis0.0495791930950809



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.