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Coexpression cluster:C1600

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Full id: C1600_blood_Whole_optic_spinal_locus_globus_thalamus



Phase1 CAGE Peaks

  Short description
Hg19::chr10:92922581..92922624,+ p5@PCGF5
Hg19::chr10:92922625..92922667,+ p6@PCGF5
Hg19::chr12:861717..861770,+ p1@WNK1
Hg19::chr5:61602025..61602053,+ p2@KIF2A
Hg19::chr5:61602055..61602083,+ p3@KIF2A


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression clusterSummary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner

link to source dataset
data


GO IDGO nameFDR corrected p-value
GO:0005813centrosome0.00275378218751093
GO:0005815microtubule organizing center0.00275378218751093
GO:0015630microtubule cytoskeleton0.0226534454319709



Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset

cell_data
uberon_data


Cell Type
Ontology termp-valuen
lymphoid lineage restricted progenitor cell2.03e-0952
lymphocyte4.39e-0953
common lymphoid progenitor4.39e-0953
Uber Anatomy
Ontology termp-valuen
adult organism1.44e-50115
neural tube5.36e-2657
neural rod5.36e-2657
future spinal cord5.36e-2657
neural keel5.36e-2657
anterior neural tube3.60e-2242
regional part of forebrain1.07e-2141
forebrain1.07e-2141
future forebrain1.07e-2141
central nervous system9.47e-2182
regional part of brain3.98e-2059
regional part of nervous system1.02e-1994
nervous system1.02e-1994
brain1.68e-1969
future brain1.68e-1969
gray matter3.90e-1834
brain grey matter3.90e-1834
telencephalon6.18e-1834
regional part of telencephalon1.83e-1733
cerebral hemisphere1.01e-1632
neural plate1.48e-1486
presumptive neural plate1.48e-1486
regional part of cerebral cortex5.27e-1422
neurectoderm2.19e-1390
cerebral cortex7.00e-1325
pallium7.00e-1325
neocortex8.82e-1320
anterior region of body1.02e-11129
craniocervical region1.02e-11129
pre-chordal neural plate2.35e-1161
head3.36e-10123
ectoderm-derived structure1.17e-08169
blood2.90e-0815
haemolymphatic fluid2.90e-0815
organism substance2.90e-0815
ectoderm3.73e-08173
presumptive ectoderm3.73e-08173
nucleus of brain8.43e-079
neural nucleus8.43e-079


Overrepresented TFBS (DNA) motifs on this co-expression clusterSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysisSummary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner

link to source dataset

data


No analysis results for this cluster

Relative expression of the co-expression clusterSummary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.
Analyst:NA

link to data source
data


This analysis result is provided for C0 - C305 clusters.