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Difference between revisions of "Coexpression cluster:C1655"

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|ontology_enrichment_disease=DOID:305!2.40e-07!106
 
|ontology_enrichment_disease=DOID:305!2.40e-07!106
 
|ontology_enrichment_uberon=UBERON:0002049!9.41e-17!79;UBERON:0007798!9.41e-17!79;UBERON:0000490!2.71e-15!138;UBERON:0000055!1.05e-14!69;UBERON:0001637!3.76e-13!42;UBERON:0003509!3.76e-13!42;UBERON:0004572!3.76e-13!42;UBERON:0001981!2.06e-12!60;UBERON:0007500!2.06e-12!60;UBERON:0004537!2.06e-12!60;UBERON:0006965!2.06e-12!60;UBERON:0004535!3.76e-12!110;UBERON:0004573!1.22e-11!33;UBERON:0004571!1.22e-11!33;UBERON:0001009!1.65e-11!113;UBERON:0004872!1.70e-11!84;UBERON:0001134!9.04e-11!61;UBERON:0002036!9.04e-11!61;UBERON:0003082!9.04e-11!61;UBERON:0002385!2.43e-10!63;UBERON:0001015!2.43e-10!63;UBERON:0000383!2.43e-10!63;UBERON:0003914!3.32e-10!118;UBERON:0000947!4.11e-10!21;UBERON:0010191!4.11e-10!21;UBERON:0004290!5.13e-09!70;UBERON:0000914!1.02e-08!83;UBERON:0002329!1.02e-08!83;UBERON:0003077!1.02e-08!83;UBERON:0003059!1.02e-08!83;UBERON:0007282!1.02e-08!83;UBERON:0009618!1.02e-08!83;UBERON:0007285!1.02e-08!83;UBERON:0000487!3.66e-08!22;UBERON:0006914!4.40e-08!25;UBERON:0000486!6.46e-08!82
 
|ontology_enrichment_uberon=UBERON:0002049!9.41e-17!79;UBERON:0007798!9.41e-17!79;UBERON:0000490!2.71e-15!138;UBERON:0000055!1.05e-14!69;UBERON:0001637!3.76e-13!42;UBERON:0003509!3.76e-13!42;UBERON:0004572!3.76e-13!42;UBERON:0001981!2.06e-12!60;UBERON:0007500!2.06e-12!60;UBERON:0004537!2.06e-12!60;UBERON:0006965!2.06e-12!60;UBERON:0004535!3.76e-12!110;UBERON:0004573!1.22e-11!33;UBERON:0004571!1.22e-11!33;UBERON:0001009!1.65e-11!113;UBERON:0004872!1.70e-11!84;UBERON:0001134!9.04e-11!61;UBERON:0002036!9.04e-11!61;UBERON:0003082!9.04e-11!61;UBERON:0002385!2.43e-10!63;UBERON:0001015!2.43e-10!63;UBERON:0000383!2.43e-10!63;UBERON:0003914!3.32e-10!118;UBERON:0000947!4.11e-10!21;UBERON:0010191!4.11e-10!21;UBERON:0004290!5.13e-09!70;UBERON:0000914!1.02e-08!83;UBERON:0002329!1.02e-08!83;UBERON:0003077!1.02e-08!83;UBERON:0003059!1.02e-08!83;UBERON:0007282!1.02e-08!83;UBERON:0009618!1.02e-08!83;UBERON:0007285!1.02e-08!83;UBERON:0000487!3.66e-08!22;UBERON:0006914!4.40e-08!25;UBERON:0000486!6.46e-08!82
 +
|tfbs_overrepresentation=0.23317,0.0958562,0.877965,0.078254,0.310241,0.43203,0.0706464,0.5903,0.0539364,0.0424746,0.221396,0.346629,0.294377,0.201017,0.235304,0.101024,0.223746,0.158251,0.0865245,0.173528,0.29418,0.211047,0.13286,0.153106,0.0683222,0.332688,0.324018,0.146582,0.227906,0.150721,0.31768,0.182756,0.0298713,0.322378,0.108398,0.136785,0.856615,0.070583,0.192426,0.108683,0.155571,0.0406818,0.222325,0.287476,0.193292,0.0596699,0.0625547,0.28382,0.0169745,0.193726,0.243359,0.0886583,0.114185,0.150136,0.308837,0.0632035,0.172598,0.328738,0.127101,0.169687,0.0485674,0.236408,0.174369,0.123348,0.0892839,0.0827236,0.515105,0.0980005,0.139298,0.262613,0.547889,0.110232,0.143944,0.190944,0.012429,0.0283664,0.155593,0.0717582,0.0613084,0.0120583,0.154245,0.348799,0.0698251,0.183986,0.436695,0.38341,0.104918,0.323505,0.790836,0.102375,0.138802,0.0812726,0.153861,0.0777027,0.138224,0.184264,0.769004,0.242703,0.149747,0.413729,0.0939617,0.416542,0.225088,0.0610111,0.337778,0.0672793,0.109136,0.00541199,0.228612,0.407248,0.285407,0.0560173,0.23661,0.0293017,0.162943,0.0556189,0.0336673,0.0926302,0.220791,0.13579,0.262107,0.331577,0.222452,0.138843,0.164723,0.277102,0.146529,0.0245339,0.136609,0.214614,0.0973103,0.121587,0.0935301,0.0376876,0.200735,0.173595,0.105753,0.0905147,0.0544577,0.0065834,0.037671,0.203496,0.316207,0.246229,0.779726,0.112838,0.159217,0.1364,0.0640569,0.193163,0.311509,0.227801,0.282656,0.0439093,0.070163,0.188135,0.121467,0.350865,0.0846706,0.0555742,0.349932,0.153706,0.186743,0.23397,0.412853,0.183121,0.065826,0.203135,0.0663482,0.463935,0.281162,0.218835,0.646289,0.0885874,0.129639,0.145577,0.22277,0.284267,0.27935,0.0586816,0.250461,0.195671,0.0452583,0.185103,0.11983,0.190123,0.286036,0.0660586,0.134265,0.272191,0.172119,0.292239,0.196376,0.351465,0.18064,0.0772176,0.126988,0.0984435,0.110187,0.176022,0.144361,0.0986228,0.0508565,0.0989516,0.21691,0.393782,0.412989,0.240045,0.319604,0.279218,0.0752697,0.167805,0.193654,0.180992,0.464566,0.265567,0.258402,0.162511,0.102771,0.165687,0.225173,0.540012,0.246322,0.253699,0.120044,0.201982,0.220536,0.139142,0.0987108,0.09782,0.754769,0.554981,0.0687568,0.124225,0.1547,0.150448,0.0774663,0.398789,0.257365,0.331711,0.285222,0.511,0.158559,0.134615,0.186192,0.217494,0.132125,0.179065,0.00824338,0.187334,0.250769,0.289141,0.289982,0.157983,0.158078,0.251693,0.172268,0.313249,0.113261,0.766691,0.00528762,0.274448,0.25718,0.204241,0.0568578,0.131428,0.131579,0.148683,0.188945,0.122666,0.419402,0.103245,0.387442,0.627158,0.14011,0.0626022,0.2074,0.769028,0.875285,0.921608,0.814323,0.748392,0.944588,0.935701,0.493893,0.808889,0.396701,0.626645,0.541514,0.460217,0.675971,0.487888,0.568246,0.486439,0.720623,0.796904,0.410803,0.43779,0.579996,0.569955,0.766049,0.780281,0.292173,0.528152,0.284119,0.601223,0.176507,0.488132,0.336705,0.604733,0.545464,0.645432,0.824163,0.714193,0.706516,0.537972,0.591562,0.668584,0.385794,0.417358,0.450485,0.665656,0.470142,0.344006,0.688397,0.785741,0.426591,0.467379,0.762263,0.437202,0.628658,0.761311,0.592924,0.438692,0.660225,0.619033,0.541742,0.762222,0.790857,0.285074,0.870229,0.943261,0.899362,0.101555,0.362164,0.289863,0.507647,0.721501,0.409489,0.80581,0.688223,0.120962,0.707862,0.379008,0.423719,0.655494,0.256985,0.109234,0.11883,0.0463546,0.779806,0.909149,0.766165,0.588284,0.843506,0.732646,0.737273,0.628596,0.337121,0.464864,0.861932,0.0740433,0.121457,0.351733,0.826323,0.773103,0.687274,0.441154,0.503865,0.294103,0.43388,0.483295,0.852766,0.418989,0.935814,0.606622,0.350461,0.495024,0.307173,0.246694,0.752605,0.598317,0.666615,0.597346,0.702113,0.961692,0.493489,0.229501,0.230597,0.555864,0.544572,0.627794,0.641833,0.383956,0.241286,0.0764074,0.217887,0.393543,0.214395,0.158849,0.732038,0.439833,0.427746,0.504398,0.456725,0.455709,0.784142,0.688249,0.708682,0.427794,0.398041,0.524026,0.347879,0.58021,0.593219,0.529253,0.64728,0.903142,0.319495,0.711229,0.827435,0.616333,0.407113,0.498776,0.738012,0.423517,0.224914,0.636791,0.706243,0.251608,0.365107,0.539805,0.356278,0.295455,0.144104,0.0972855,0.710825,0.80526,0.508875,0.725283,0.512109,0.658411,0.578577,0.818493,0.809533,0.469232,0.113555,0.0910724,0.299839,0.126587,0.0940929,0.22877,0.343849,0.315824,0.622796,0.621499,0.29873,0.179502,0.43406,0.0715061,0.452515,0.201779,0.214491,0.171725,0.412647,0.102448,0.550877,0.029672,0.453305,0.421335,0.561724,0.0762646,0.266371,0.183582,0.168118,0.145381,0.140277,0.251925,0.172066,0.0720324,0.00647589,0.19738,0.0228128,0.32541,0.301472,0.507714,0.0818982,0.134306,0.108669,0.284804,0.178494,0.338195,0.490571,0.304235,0.210475,0.294266,0.0790025,0.310539,0.580279,0.203728,0.275452,0.288155,0.265827,0.141761,0.153627,0.0186891,0.342497,0.171961,0.415228,0.00800917,0.272406,0.223952,0.327153,0.0496113,0.20949,0.0730994,0.0857377,0.323267,0.24204,0.129414,0.157037,0.252398,0.197279,0.146467,0.0912686,0.425114,0.7034,0.218241,0.0242146,0.10708,0.327369,0.339826,0.12998,0.123097,0.254847,0.300809,0.0898207,0.126545,0.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}}
 
}}

Revision as of 08:31, 8 August 2012


Full id: C1655_large_mesothelioma_Fibroblast_giant_oral_mesenchymal_mucinous



Phase1 CAGE Peaks

  Short description
Hg19::chr12:104674502..104674520,- p5@ENST00000549807
Hg19::chr12:104674521..104674536,- p4@ENST00000549807
Hg19::chr12:104674543..104674573,- p2@ENST00000549807
Hg19::chr12:104674575..104674595,- p3@ENST00000549807
Hg19::chr12:104674604..104674628,- p1@ENST00000549807


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression clusterSummary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner

link to source dataset
data


No GOStat results

Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset

cell_data
uberon_data
disease_data


Uber Anatomy
Ontology termp-valuen
vasculature9.41e-1779
vascular system9.41e-1779
unilaminar epithelium2.71e-15138
vessel1.05e-1469
artery3.76e-1342
arterial blood vessel3.76e-1342
arterial system3.76e-1342
blood vessel2.06e-1260
epithelial tube open at both ends2.06e-1260
blood vasculature2.06e-1260
vascular cord2.06e-1260
cardiovascular system3.76e-12110
systemic artery1.22e-1133
systemic arterial system1.22e-1133
circulatory system1.65e-11113
splanchnic layer of lateral plate mesoderm1.70e-1184
skeletal muscle tissue9.04e-1161
striated muscle tissue9.04e-1161
myotome9.04e-1161
muscle tissue2.43e-1063
musculature2.43e-1063
musculature of body2.43e-1063
epithelial tube3.32e-10118
aorta4.11e-1021
aortic system4.11e-1021
dermomyotome5.13e-0970
somite1.02e-0883
paraxial mesoderm1.02e-0883
presomitic mesoderm1.02e-0883
presumptive segmental plate1.02e-0883
trunk paraxial mesoderm1.02e-0883
presumptive paraxial mesoderm1.02e-0883
simple squamous epithelium3.66e-0822
squamous epithelium4.40e-0825
multilaminar epithelium6.46e-0882
Disease
Ontology termp-valuen
carcinoma2.40e-07106


Overrepresented TFBS (DNA) motifs on this co-expression clusterSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysisSummary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner

link to source dataset

data


No analysis results for this cluster

Relative expression of the co-expression clusterSummary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.
Analyst:NA

link to data source
data


This analysis result is provided for C0 - C305 clusters.