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{{Coexpression_clusters
{{Coexpression_clusters
|full_id=C2145_Mesenchymal_Alveolar_Renal_Placental_nonsmall_Bronchial_left
|full_id=C2145_Mesenchymal_Alveolar_Renal_Placental_nonsmall_Bronchial_left
|gostat_on_coexpression_clusters=GO:0005739!mitochondrion!0.00246685015740525!64978;6182;1537$GO:0045155!electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity!0.0085656256290494!1537$GO:0006390!transcription from mitochondrial promoter!0.0142747820013017!6182$GO:0044429!mitochondrial part!0.0214058702371865!6182;1537$GO:0000315!organellar large ribosomal subunit!0.0214058702371865!6182$GO:0005762!mitochondrial large ribosomal subunit!0.0214058702371865!6182$GO:0005840!ribosome!0.0255028847072952!64978;6182$GO:0044444!cytoplasmic part!0.0299280631346191!64978;6182;1537$GO:0030529!ribonucleoprotein complex!0.0354431211698454!64978;6182$GO:0000313!organellar ribosome!0.0396560987964519!6182$GO:0005761!mitochondrial ribosome!0.0396560987964519!6182
|id=C2145
|id=C2145
}}
}}

Revision as of 17:36, 18 May 2012


Full id: C2145_Mesenchymal_Alveolar_Renal_Placental_nonsmall_Bronchial_left



Phase1 CAGE Peaks

Hg19::chr11:62439136..62439162,+p1@C11orf83
Hg19::chr17:73900954..73901003,-p1@MRPL38
Hg19::chr17:79670440..79670524,+p1@MRPL12
p1@SLC25A10
Hg19::chr8:145149957..145150006,+p1@CYC1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0005739mitochondrion0.00246685015740525
GO:0045155electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity0.0085656256290494
GO:0006390transcription from mitochondrial promoter0.0142747820013017
GO:0044429mitochondrial part0.0214058702371865
GO:0000315organellar large ribosomal subunit0.0214058702371865
GO:0005762mitochondrial large ribosomal subunit0.0214058702371865
GO:0005840ribosome0.0255028847072952
GO:0044444cytoplasmic part0.0299280631346191
GO:0030529ribonucleoprotein complex0.0354431211698454
GO:0000313organellar ribosome0.0396560987964519
GO:0005761mitochondrial ribosome0.0396560987964519



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.