Personal tools

Coexpression cluster:C2180

From FANTOM5_SSTAR

Revision as of 17:36, 18 May 2012 by Autoedit (talk | contribs)
Jump to: navigation, search
The printable version is no longer supported and may have rendering errors. Please update your browser bookmarks and please use the default browser print function instead.


Full id: C2180_Eosinophils_CD14_Neutrophils_CD19_Natural_Basophils_CD4



Phase1 CAGE Peaks

Hg19::chr12:105501983..105502018,-p@chr12:105501983..105502018
-
Hg19::chr14:24711806..24711861,-p1@TINF2
Hg19::chr15:45003504..45003582,-p1@PATL2
Hg19::chr16:72127670..72127755,+p2@DHX38


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0042162telomeric DNA binding0.0150498688801005
GO:0007004telomere maintenance via telomerase0.0150498688801005
GO:0004004ATP-dependent RNA helicase activity0.0150498688801005
GO:0008186RNA-dependent ATPase activity0.0150498688801005
GO:0032200telomere organization and biogenesis0.0150498688801005
GO:0000723telomere maintenance0.0150498688801005
GO:0003724RNA helicase activity0.0150498688801005
GO:0000781chromosome, telomeric region0.0150498688801005
GO:0006278RNA-dependent DNA replication0.0226427060366972
GO:0000375RNA splicing, via transesterification reactions0.0226427060366972
GO:0000398nuclear mRNA splicing, via spliceosome0.0226427060366972
GO:0000377RNA splicing, via transesterification reactions with bulged adenosine as nucleophile0.0226427060366972
GO:0005681spliceosome0.0414611412249278



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.