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Coexpression cluster:C2276


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Full id: C2276_anaplastic_pituitary_locus_skeletal_tongue_diaphragm_neuroblastoma

Phase1 CAGE Peaks

  Short description
Hg19::chr14:101202516..101202528,+ p@chr14:101202516..101202528
Hg19::chr14:101202697..101202709,+ p@chr14:101202697..101202709
Hg19::chr14:101202716..101202736,+ p@chr14:101202716..101202736
Hg19::chr4:72052646..72052664,+ p5@SLC4A4

Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset

No results for this coexpression

Enriched Gene Ontology terms on this co-expression clusterSummary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner

link to source dataset

No GOStat results

Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset


Uber Anatomy
Ontology termp-valuen
regional part of nervous system5.90e-2394
nervous system5.90e-2394
central nervous system1.67e-2182
adult organism2.36e-21115
neural tube8.40e-2057
neural rod8.40e-2057
future spinal cord8.40e-2057
neural keel8.40e-2057
regional part of brain9.08e-1859
future brain7.84e-1669
regional part of forebrain5.11e-1541
future forebrain5.11e-1541
gray matter8.03e-1534
brain grey matter8.03e-1534
anterior neural tube2.21e-1442
regional part of telencephalon9.15e-1433
cerebral hemisphere4.54e-1332
neural plate1.42e-1286
presumptive neural plate1.42e-1286
cerebral cortex5.77e-1025
ectoderm-derived structure6.88e-10169
presumptive ectoderm1.67e-09173
pre-chordal neural plate4.02e-0961
regional part of cerebral cortex4.58e-0922
anterior region of body1.65e-08129
craniocervical region1.65e-08129

Overrepresented TFBS (DNA) motifs on this co-expression clusterSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs

Jaspar motifs

Novel motifs

JASPAR motifs



ENCODE TF ChIP-seq peak enrichment analysisSummary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner

link to source dataset


(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)


Relative expression of the co-expression clusterSummary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.

link to data source

This analysis result is provided for C0 - C305 clusters.