Personal tools

Coexpression cluster:C2355


Revision as of 06:04, 12 September 2012 by Autoedit (talk | contribs)
Jump to: navigation, search

Full id: C2355_Reticulocytes_chronic_acute_CD34_skeletal_Skeletal_leukemia

Phase1 CAGE Peaks

  Short description
Hg19::chr15:91445275..91445289,+ p28@MAN2A2
Hg19::chr1:3689325..3689369,+ p2@LOC388588
Hg19::chr2:190446738..190446765,- p3@SLC40A1
Hg19::chr9:20382446..20382493,- p4@MLLT3

Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset

No results for this coexpression

Enriched Gene Ontology terms on this co-expression clusterSummary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner

link to source dataset

GO IDGO nameFDR corrected p-value
GO:0004572mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity0.0185441379597977
GO:0005381iron ion transmembrane transporter activity0.0278129317154168
GO:0004559alpha-mannosidase activity0.0308996186091742
GO:0006013mannose metabolic process0.0347569542511018
GO:0015924mannosyl-oligosaccharide mannosidase activity0.0463153233814627
GO:0046915transition metal ion transmembrane transporter activity0.0463153233814627
GO:0015923mannosidase activity0.0463153233814627
GO:0015082di-, tri-valent inorganic cation transmembrane transporter activity0.0479684279760137
GO:0055072iron ion homeostasis0.0479684279760137
GO:0006879cellular iron ion homeostasis0.0479684279760137
GO:0006826iron ion transport0.0479684279760137

Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset


Uber Anatomy
Ontology termp-valuen
adult organism2.87e-14115
Ontology termp-valuen
myeloid leukemia6.20e-0931

Overrepresented TFBS (DNA) motifs on this co-expression clusterSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs

Jaspar motifs

Novel motifs

JASPAR motifs



ENCODE TF ChIP-seq peak enrichment analysisSummary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner

link to source dataset


(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)


Relative expression of the co-expression clusterSummary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.

link to data source

This analysis result is provided for C0 - C305 clusters.