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|ontology_enrichment_disease=DOID:162!2.09e-47!235;DOID:14566!8.20e-46!239;DOID:0050686!6.57e-27!137;DOID:2531!1.29e-26!51;DOID:0060083!1.29e-26!51;DOID:1240!2.62e-21!39;DOID:0050687!9.66e-21!143;DOID:8692!9.97e-17!31;DOID:305!1.87e-16!106;DOID:0060058!7.51e-07!10
 
|ontology_enrichment_disease=DOID:162!2.09e-47!235;DOID:14566!8.20e-46!239;DOID:0050686!6.57e-27!137;DOID:2531!1.29e-26!51;DOID:0060083!1.29e-26!51;DOID:1240!2.62e-21!39;DOID:0050687!9.66e-21!143;DOID:8692!9.97e-17!31;DOID:305!1.87e-16!106;DOID:0060058!7.51e-07!10
 
|ontology_enrichment_uberon=
 
|ontology_enrichment_uberon=
 +
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}}
 
}}

Revision as of 09:15, 8 August 2012


Full id: C2388_granulocyte_non_Hodgkin_Burkitt_acute_Reticulocytes_embryonic



Phase1 CAGE Peaks

  Short description
Hg19::chr16:72698834..72698913,- p@chr16:72698834..72698913
-
Hg19::chr1:93646238..93646298,+ p1@CCDC18
Hg19::chr3:121264813..121264846,- p1@POLQ
Hg19::chr3:121264848..121264859,- p2@POLQ


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression clusterSummary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner

link to source dataset
data


GO IDGO nameFDR corrected p-value
GO:0003887DNA-directed DNA polymerase activity0.0288472860002355
GO:0003684damaged DNA binding0.0288472860002355



Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset

cell_data

disease_data


Cell Type
Ontology termp-valuen
lymphocyte of B lineage1.99e-0824
pro-B cell1.99e-0824
hematopoietic stem cell9.02e-07172
angioblastic mesenchymal cell9.02e-07172
Disease
Ontology termp-valuen
cancer2.09e-47235
disease of cellular proliferation8.20e-46239
organ system cancer6.57e-27137
hematologic cancer1.29e-2651
immune system cancer1.29e-2651
leukemia2.62e-2139
cell type cancer9.66e-21143
myeloid leukemia9.97e-1731
carcinoma1.87e-16106
lymphoma7.51e-0710


Overrepresented TFBS (DNA) motifs on this co-expression clusterSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysisSummary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner

link to source dataset

data


No analysis results for this cluster

Relative expression of the co-expression clusterSummary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.
Analyst:NA

link to data source
data


This analysis result is provided for C0 - C305 clusters.