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Coexpression cluster:C254: Difference between revisions

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|gostat_on_coexpression_clusters=GO:0043012!regulation of fusion of sperm to egg plasma membrane!0.0376730967742162!79400$GO:0010155!regulation of proton transport!0.0376730967742162!79400$GO:0015252!hydrogen ion channel activity!0.0376730967742162!79400$GO:0016175!superoxide-generating NADPH oxidase activity!0.0376730967742162!79400
|gostat_on_coexpression_clusters=GO:0043012!regulation of fusion of sperm to egg plasma membrane!0.0376730967742162!79400$GO:0010155!regulation of proton transport!0.0376730967742162!79400$GO:0015252!hydrogen ion channel activity!0.0376730967742162!79400$GO:0016175!superoxide-generating NADPH oxidase activity!0.0376730967742162!79400
|id=C254
|id=C254
|ontology_enrichment_celltype=CL:0000055!1.31e-20!180;CL:0000222!2.12e-18!119;CL:0000220!1.46e-15!246;CL:0002321!9.42e-15!248;CL:0000183!1.06e-12!59;CL:0000680!8.58e-12!57;CL:0000056!8.58e-12!57;CL:0000355!8.58e-12!57;CL:0000548!1.17e-11!679;CL:0000004!1.17e-11!679;CL:0000255!1.17e-11!679;CL:0000012!4.55e-11!682;CL:0000187!5.83e-11!54;CL:0002371!1.21e-10!591;CL:0000144!4.78e-10!625;CL:0000057!1.48e-09!75;CL:0000192!8.68e-09!42;CL:0000514!8.68e-09!42;CL:0000393!1.20e-08!60;CL:0000211!1.20e-08!60;CL:0000003!5.58e-08!722;CL:0000359!1.86e-07!32;CL:0000213!2.82e-07!57;CL:0000215!2.82e-07!57;CL:0002139!5.34e-07!24
|ontology_enrichment_celltype=
|ontology_enrichment_disease=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0002049!5.94e-16!79;UBERON:0007798!5.94e-16!79;UBERON:0004535!2.45e-12!110;UBERON:0000055!3.30e-12!69;UBERON:0005256!3.40e-12!143;UBERON:0000914!4.86e-12!83;UBERON:0002329!4.86e-12!83;UBERON:0003077!4.86e-12!83;UBERON:0003059!4.86e-12!83;UBERON:0007282!4.86e-12!83;UBERON:0009618!4.86e-12!83;UBERON:0007285!4.86e-12!83;UBERON:0002100!6.16e-12!216;UBERON:0000490!7.40e-12!138;UBERON:0000486!9.31e-12!82;UBERON:0001009!1.92e-11!113;UBERON:0004290!1.14e-10!70;UBERON:0001981!1.89e-10!60;UBERON:0007500!1.89e-10!60;UBERON:0004537!1.89e-10!60;UBERON:0006965!1.89e-10!60;UBERON:0001637!6.23e-10!42;UBERON:0003509!6.23e-10!42;UBERON:0004572!6.23e-10!42;UBERON:0003914!1.95e-09!118;UBERON:0003104!2.05e-09!238;UBERON:0009142!2.05e-09!238;UBERON:0001134!3.95e-09!61;UBERON:0002036!3.95e-09!61;UBERON:0003082!3.95e-09!61;UBERON:0004573!4.56e-09!33;UBERON:0004571!4.56e-09!33;UBERON:0004872!8.59e-09!84;UBERON:0002385!2.37e-08!63;UBERON:0001015!2.37e-08!63;UBERON:0000383!2.37e-08!63;UBERON:0000475!4.45e-07!365;UBERON:0000119!6.19e-07!312
|ontology_enrichment_uberon=UBERON:0002367!2.25e-19!11;UBERON:0010147!2.25e-19!11;UBERON:0009846!2.25e-19!11;UBERON:0003353!2.25e-19!11;UBERON:0004902!2.25e-19!11;UBERON:0003820!2.25e-19!11;UBERON:0009847!2.25e-19!11;UBERON:0003937!6.76e-18!12;UBERON:0005399!6.76e-18!12;UBERON:0000162!1.43e-15!14;UBERON:0001353!1.43e-15!14;UBERON:0000163!1.43e-15!14;UBERON:0006866!1.43e-15!14;UBERON:0000164!1.43e-15!14;UBERON:0000931!1.43e-15!14;UBERON:0004122!1.22e-14!15;UBERON:0001046!6.95e-12!19;UBERON:0003101!1.80e-10!22;UBERON:0000079!1.80e-10!22;UBERON:0003064!1.52e-08!28;UBERON:0000077!2.67e-08!29;UBERON:0000161!5.81e-07!36;UBERON:0005153!8.21e-07!37
|tf_chipseq_enrich=ZZZ3#26009;3:14.083130143249:0.00130203389673015:0.0087224578666196
|tf_chipseq_enrich=ZZZ3#26009;3:14.083130143249:0.00130203389673015:0.0087224578666196
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4,0.152164,0.800925,0.162814,0.617091,0.0515006,0.625815,0.515788,0.449866,0.490354,0.875085,0.825363,0.335151,0.21009,0.961944,0.984733,0.020416,0.932191,0.79163,0.495702,0.648483,0.952578,0.891507,0.135652,0.000221957,0.585743,0.389411,0.997489,0.929667,0.490123,0.788967,0.617948,0.741106,0.130724,0.128011,0.694278,0.218925,0.616575,0.837435,0.978523,0.38939,0.959993,0.426062,0.261362,0.050552,0.13961,0.12158,0.0955983,0.047313,0.794816,0.950078,0.0150827,0.561238,0.816348,0.782061,0.436534,0.745944,0.859941,0.903616,0.690656,0.975995,0.0901554,0.0137026,0.831328,0.0584275,0.0246479,0.385441,0.812061,0.741133,0.444791,0.73026,0.316484,0.435046,0.0110662,0.241071,0.92878,0.00175766,0.0322696,0.120951,0.864395,0.635055,0.201643,0.998043,0.656175,0.635914,0.0893966,0.715742,0.986546,0.0739231,0.459867,0.664929,0.232368,0.810715,0.996422,0.980379,0.00133258,0.579793,0.332053,0.311733,0.577417,0.819659,0.0462715,0.737111,0.548145,0.862646,0.710253,0.633338,0.774373,0.479593,0.435174,0.542877,0.610222,0.610595,0.0870914,0.831048,0.292189,4.03297e-05,0.632393,0.940789,0.0475528,0.353195,0.770675,0.167956,0.984796,0.838218,0.509932,0.960394,0.41438,0.768033,0.00544176,0.157302,0.293491,0.999451,0.027801,0.718689,0.805792,0.652216,0.929298,0.937677,0.824787,0.32227,0.825331,0.164112,0.918659,0.449253,0.370681,0.130593,0.884032,0.774508,0.679054,0.0180991,0.868898,0.0662054,0.837177,0.241203,0.596012,0.361077,0.92381,0.265871,0.395214,0.84441,0.334093,0.356027,0.380716,0.220685,0.123215,0.955202,0.284784,0.763828,0.139303,0.327806,0.7595,0.857129,0.644955,0.992014,0.964574,0.921092,0.291427,0.999862,0.893572,0.464625,0.99393,0.689117,0.175259,0.0380237,0.571176,0.890518,0.558654,0.398645,0.6535,0.916329,0.649292,0.387392,0.470837,0.220543,0.320526,0.0554304,0.876821,0.00203726,0.908957,0.407892,0.0215323,0.493312,0.271522,0.000472015,0.699601,0.831652,0.0136985,0.0545032,0.620371,0.998706,0.636945,0.0290802,0.567866,0.215551,0.00587366,0.0983858,0.961693,0.179156,0.132821,0.193063,0.6099,0.927034,0.000532976,0.317576,0.0123651,0.0795366,0.0347429,0.424107,0.201046,0.56875,0.467277,0.0768511,0.667029,0.351957,0.271189,0.492982,0.0504854,0.695395,0.680629,0.688544,0.770705,0.936296,0.715413,0.942469,0.898118,0.185023,0.00703566,0.0458273,0.391049,0.0083795,0.12136,0.000134651,0.550637,0.924984,0.679114,0.820669,0.198751,0.0408299,0.586076,0.289577,0.371255,0.00226556,0.744143,0.88235,0.442306,0.207945,0.660809,0.0432956,0.534306,0.000209572,0.0732559,0.544991,0.40856,0.874039,0.000416269,0.379795,0.943487,0.00831362,0.423426,0.433873,0.211985,0.000108375,0.903353,0.00132171,0.000732622,0.153534,0.921266,0.965785,0.0947993,0.0860462,0.772397,0.119872,0.326498,0.635412,0.0482129,0.0327474,0.933838,0.536014,0.013176,0.00200968,0.145227,0.50038,0.0930157,0.979093,0.181885,0.901022,0.873501,0.0006317,0.10354,0.738546,0.284978,0.688861,0.392492,0.429946,0.0493027,0.196772,0.0797089,0.0121895,0.72247,0.310599,0.248676,0.0983014,0.251586,0.00162825,0.318442,0.699746,0.37235,0.309002,0.10163,0.717203,0.340304,0.0804858,0.208384,0.50039,0.458471,0.16508,0.972731,0.131049,0.0184212,0.630871,0.832126,0.037469,0.0213062,0.323989,0.00490713,0.889486,0.940687,0.445993,0.548524,0.640372,0.748105,0.644163,0.101151,0.441789,0.692824,6.91125e-06,0.68755,0.362096,0.158627,0.951006,0.156445,0.582607,0.248717,0.756661,0.476568,0.818009,0.813672,0.229121,0.959901,0.135058,0.557532,0.426522,0.965316,0.879898,0.985644,0.00473546,0.712764,0.875504,3.2732e-05,0.519125,0.466667,0.0766147,0.522853,0.430674,0.495888,0.894767,0.849876,0.811772,0.0117849,0.781409,0.689227,0.561086,0.214251,0.799474,0.331951,0.75812,0.967744,0.150209,0.280858,0.454672,0.354444,0.934782,0.821078,0.00487531,0.0306116,0.598028,0.547321,0.613886,0.188527,0.315532,0.0706428,0.371099,0.526998,0.580771,0.647942,0.917851,0.337817,0.610273,0.0135342,0.8951,0.96313,0.434927,0.0568729,0.568165,0.139364,0.525164,0.240513,0.390397,0.968677,0.460048,0.720941,0.574165,0.150487,0.195495,0.914776,0.36234,0.122709,0.162268,0.361281,0.876996,0.627091,0.00142815,0.960431,0.332665,0.255268,0.319,0.00871178,0.552328,0.908239,0.033646,0.260838,0.106708,0.842281,0.0087433,0.895881,0.875002,0.059509,0.601592,0.180904,0.33943,0.853231,0.608051,0.609235,0.150062,0.748639,0.506774,0.608967,0.782337,0.150436,0.767118,0.0679967,0.829043,0.288408,0.763384,0.523808,0.675999,0.890316,0.674376,0.290424,0.688599,0.740339,0.0102743,0.584507,0.535555,0.69213,0.473769,0.470826,0.234939,0.544158,0.148764,0.0673848,0.0340669,0.732268,0.890579,0.241648,0.183806,0.446493,0.0206366,0.95856,0.425243,0.668493,0.270713,0.0357874,0.347691,0.103161,0.521859,0.513049,0.835922,0.230917,0.618464,0.130424,0.624203,0.15801,0.3103,0.972761,0.206251,0.666969,0.221853,0.0042973,0.432822,0.8118,0.990909,0.930931,0.0076138,0.819748,0.0691245,0.00286608,0.219764,0.563392,0.175926,0.132434,0.447664,0.272174,0.012524,0.962731,0.945466,0.235582,0.128621,0.550835,0.238075
}}
}}

Revision as of 14:08, 19 October 2012


Full id: C254_prostate_rhabdomyosarcoma_seminal_Fibroblast_transitionalcell_Smooth_Iris



Phase1 CAGE Peaks

Hg19::chr10:33624520..33624578,-p@chr10:33624520..33624578
-
Hg19::chr10:38146468..38146475,-p12@ZNF248
Hg19::chr10:38146482..38146507,-p4@ZNF248
Hg19::chr10:4808729..4808734,-p@chr10:4808729..4808734
-
Hg19::chr11:1221057..1221104,+p1@uc009ycs.1
Hg19::chr11:66583418..66583427,+p6@C11orf80
Hg19::chr12:52679734..52679755,-p@chr12:52679734..52679755
-
Hg19::chr13:66882589..66882629,+p@chr13:66882589..66882629
+
Hg19::chr14:62393999..62394005,+p@chr14:62393999..62394005
+
Hg19::chr14:62583348..62583354,+p3@FLJ43390
Hg19::chr15:69339407..69339410,+p3@NOX5
Hg19::chr15:74220458..74220472,-p11@LOC100287616
Hg19::chr15:74220487..74220499,-p9@LOC100287616
Hg19::chr15:74220519..74220531,-p8@LOC100287616
Hg19::chr15:74220536..74220564,-p3@LOC100287616
Hg19::chr15:74220590..74220602,-p15@LOC100287616
Hg19::chr15:74220651..74220670,-p5@LOC100287616
Hg19::chr17:46806016..46806029,-p5@HOXB13
Hg19::chr17:46806373..46806386,-p6@HOXB13
Hg19::chr17:46806404..46806415,-p7@HOXB13
Hg19::chr17:46806554..46806558,-p9@HOXB13
Hg19::chr17:49141793..49141801,-p@chr17:49141793..49141801
-
Hg19::chr1:85395365..85395368,-p6@MCOLN2
Hg19::chr20:24115408..24115418,+p@chr20:24115408..24115418
+
Hg19::chr20:58410917..58410928,+p12@PHACTR3
Hg19::chr20:58411263..58411271,+p34@PHACTR3
Hg19::chr21:46331846..46331872,-p29@ITGB2
Hg19::chr22:39410287..39410302,+p2@APOBEC3C
Hg19::chr2:189992577..189992580,-p@chr2:189992577..189992580
-
Hg19::chr2:36806022..36806034,-p20@FEZ2
Hg19::chr3:108160535..108160548,-p@chr3:108160535..108160548
-
Hg19::chr3:146464294..146464304,+p@chr3:146464294..146464304
+
Hg19::chr4:69614262..69614265,-p@chr4:69614262..69614265
-
Hg19::chr5:147297683..147297729,-p@chr5:147297683..147297729
-
Hg19::chr5:151055872..151055921,-p14@SPARC
Hg19::chr6:47010258..47010273,-p5@GPR110
Hg19::chr6:47010286..47010292,-p11@GPR110
Hg19::chr6:47010305..47010311,-p8@GPR110
Hg19::chr7:103086717..103086724,+p@chr7:103086717..103086724
+
Hg19::chr7:103086740..103086747,+p@chr7:103086740..103086747
+
Hg19::chr7:103310094..103310097,+p@chr7:103310094..103310097
+
Hg19::chr7:31855776..31855807,-p@chr7:31855776..31855807
-
Hg19::chr7:48251843..48251884,+p@chr7:48251843..48251884
+
Hg19::chr8:38687332..38687338,+p@chr8:38687332..38687338
+
Hg19::chr9:123788118..123788127,-p@chr9:123788118..123788127
-
Hg19::chr9:35753022..35753030,-p4@CU674847
Hg19::chr9:35753038..35753047,-p2@CU674847
Hg19::chr9:35753063..35753064,-p5@CU674847
Hg19::chr9:35754222..35754237,-p3@MSMP
Hg19::chr9:35754253..35754279,-p1@MSMP
Hg19::chr9:35754350..35754382,-p4@MSMP


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0043012regulation of fusion of sperm to egg plasma membrane0.0376730967742162
GO:0010155regulation of proton transport0.0376730967742162
GO:0015252hydrogen ion channel activity0.0376730967742162
GO:0016175superoxide-generating NADPH oxidase activity0.0376730967742162



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
ZZZ3#26009314.0831301432490.001302033896730150.0087224578666196



Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

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