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Coexpression cluster:C2877


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Full id: C2877_CD14_Eosinophils_neuroectodermal_CD8_cord_CD4_Natural

Phase1 CAGE Peaks

  Short description
Hg19::chr7:130645970..130645981,- p@chr7:130645970..130645981
Hg19::chr7:130645982..130645997,- p@chr7:130645982..130645997
Hg19::chr7:130645999..130646023,- p@chr7:130645999..130646023
Hg19::chr7:130646084..130646098,- p@chr7:130646084..130646098

Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset

No results for this coexpression

Enriched Gene Ontology terms on this co-expression clusterSummary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner

link to source dataset

No GOStat results

Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset


Cell Type
Ontology termp-valuen
hematopoietic stem cell1.06e-28172
angioblastic mesenchymal cell1.06e-28172
nongranular leukocyte4.57e-28119
hematopoietic cell6.31e-28182
hematopoietic oligopotent progenitor cell6.02e-27165
hematopoietic multipotent progenitor cell6.02e-27165
hematopoietic lineage restricted progenitor cell3.76e-22124
mesenchymal cell3.58e-20358
motile cell5.27e-19390
connective tissue cell1.10e-18365
CD14-positive, CD16-negative classical monocyte2.77e-1742
common lymphoid progenitor1.70e-1653
lymphoid lineage restricted progenitor cell4.38e-1652
classical monocyte2.51e-1445
multi fate stem cell9.88e-13430
somatic stem cell1.62e-12436
myeloid leukocyte9.47e-1276
myeloid cell1.04e-11112
common myeloid progenitor1.04e-11112
stem cell1.27e-11444
macrophage dendritic cell progenitor5.50e-1165
monopoietic cell8.76e-1163
native cell2.84e-10722
T cell2.91e-1025
pro-T cell2.91e-1025
mature alpha-beta T cell1.85e-0818
alpha-beta T cell1.85e-0818
immature T cell1.85e-0818
mature T cell1.85e-0818
immature alpha-beta T cell1.85e-0818
granulocyte monocyte progenitor cell4.21e-0871
somatic cell5.44e-08591
myeloid lineage restricted progenitor cell9.98e-0870
animal cell8.82e-07679
eukaryotic cell8.82e-07679
Uber Anatomy
Ontology termp-valuen
connective tissue4.35e-20375
hematopoietic system4.82e-12102
blood island4.82e-12102
hemolymphoid system6.73e-10112
skeletal element8.05e-10101
skeletal system8.05e-10101
bone element1.15e-0986
bone marrow6.75e-0980

Overrepresented TFBS (DNA) motifs on this co-expression clusterSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs

Jaspar motifs

Novel motifs

JASPAR motifs



ENCODE TF ChIP-seq peak enrichment analysisSummary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner

link to source dataset


No analysis results for this cluster

Relative expression of the co-expression clusterSummary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.

link to data source

This analysis result is provided for C0 - C305 clusters.