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{{Coexpression_clusters
 
{{Coexpression_clusters
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|coexpression_dpi_cluster_scores_median=0.0362496447385107,0,0,0,0.160456854061196,0,0,0,0,0,0,0,0.09199543660556,0,0,0,0,0,0,0,0,0,0,0.052541902481501,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0434875120355909,0.0182814710679588,0.444668647227221,0.118846070556646,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0241110376195271,0,0.0537578863413185,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0191212414416402,0.0858541854836475,0.11650049142629,0.0398626459945077,0,0.0767353931304631,0,0,0.119254163581544,0.051055482450413,0.0238698307237727,0.0409115770312979,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0901171382917238,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.200225029120878,0.301628187878816,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.023077989779793,0.0785711816082655,0.0791857269139835,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.140194803500337,0,0.08223381854984,0.053716938525557,0,0,0.0323887863409804,0,0.031142358737545,0.0354918406012271,0.0478254915108506,0,0.0477460562445518,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0495726269590695,0,0,0,0,0,0,0,0,0.070988575821274,0,0.0310094911974069,0.0751493992397825,0.121759826693598,0.0294059092864159,0,0.0355844555194764,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.23033305409191,0.11292814946238,0.103995002545457,0,0,0,0,0,0.0394544993028877,0,0,0,0,0,0,0,0,0.0204283766509788,0,0,0,0,0,0,0,0.118394496259328,0,0,0,0,0,0,0,0,0,0,0.0562266902389565,0,0,0,0.0160978224214165,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.035372572826539,0,0,0,0,0.0141638297223524,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.19331600339248,0,0,0,0.0141195453442412,0,0,0,0,0,0,0,0,0,0.0323699351672233,0.027983230928169,0,0,0,0.0248994672777727,0,0,0.0679131845393035,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0499379825215864,0,0,0,0,0,0,0,0,0,0,0,0.0485748203103998,0.141541643597484,0,0,0,0,0,0,0,0.0130819689967123,0.507778475324302,0,0,0,0,0,0,0.0567225833435015,0,0,0,0,0,0.0447476819101155,0,0.0627463460232421,0.0299435435391435,0.0600554709333225,0,0.058722806456058,0,0,0,0,0,0,0,0,0,0,0,0.064101977765766,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.245554207256309,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.03976037701639,0,0,0,0,0.0290415862703977,0.0325050538702846,0,0,0,0,0,0,0,0,0.0441798658901723,0,0,0,0,0,0.0400629026399716,0,0,0,0,0,0.0874964475451495,0,0,0.093153451727105,0,0,0,0,0,0,0,0.0138323107379372,0,0,0.059293116754279,0,0,0,0,0,0.0695959753493367,0,0,0,0,0,0,0,0,0.0461258594617195,0.077069968711861,0,0,0,0,0,0,0,0,0.0583019496296905,0,0.0859671683977995,0,0,0,0,0.0845465357680757,0,0,0,0,0,0,0.0389215882764182,0,0,0.0635287757415635,0,0,0,0,0,0,0,0,0,0,0.0142838961131921,0,0,0.120771999708326,0,0.0780664995445025,0,0,0,0.0403092142030732,0.520005736910818,0.585784246831543,0.47642380872439,0.527467111816534,0.654739528050949,0,0,0,0,0,0,0,0.0492506742011634,0,0.078491538131073,0,0.0399623790051892,0.042317914903657,0.0623597393457245,0,0,0,0,0,0,0,0,0,0
 
|full_id=C2922_testis_testicular_medulloblastoma_nasal_Mallassezderived_breast_heart
 
|full_id=C2922_testis_testicular_medulloblastoma_nasal_Mallassezderived_breast_heart
 
|gostat_on_coexpression_clusters=GO:0007128!meiotic prophase I!0.00618101538826815!55124$GO:0051324!prophase!0.00618101538826815!55124$GO:0007127!meiosis I!0.0194186137591271!55124$GO:0051327!M phase of meiotic cell cycle!0.0208780317236321!55124$GO:0007126!meiosis!0.0208780317236321!55124$GO:0051321!meiotic cell cycle!0.0208780317236321!55124$GO:0007283!spermatogenesis!0.0466578980278243!55124$GO:0048232!male gamete generation!0.0466578980278243!55124
 
|gostat_on_coexpression_clusters=GO:0007128!meiotic prophase I!0.00618101538826815!55124$GO:0051324!prophase!0.00618101538826815!55124$GO:0007127!meiosis I!0.0194186137591271!55124$GO:0051327!M phase of meiotic cell cycle!0.0208780317236321!55124$GO:0007126!meiosis!0.0208780317236321!55124$GO:0051321!meiotic cell cycle!0.0208780317236321!55124$GO:0007283!spermatogenesis!0.0466578980278243!55124$GO:0048232!male gamete generation!0.0466578980278243!55124

Revision as of 06:43, 12 September 2012


Full id: C2922_testis_testicular_medulloblastoma_nasal_Mallassezderived_breast_heart



Phase1 CAGE Peaks

  Short description
Hg19::chr8:22132822..22132844,+ p2@PIWIL2
Hg19::chr8:22132847..22132876,+ p1@PIWIL2
Hg19::chr8:22132882..22132891,+ p6@PIWIL2
Hg19::chrX:114524245..114524256,+ p2@LUZP4


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression clusterSummary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner

link to source dataset
data


GO IDGO nameFDR corrected p-value
GO:0007128meiotic prophase I0.00618101538826815
GO:0051324prophase0.00618101538826815
GO:0007127meiosis I0.0194186137591271
GO:0051327M phase of meiotic cell cycle0.0208780317236321
GO:0007126meiosis0.0208780317236321
GO:0051321meiotic cell cycle0.0208780317236321
GO:0007283spermatogenesis0.0466578980278243
GO:0048232male gamete generation0.0466578980278243



Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset

cell_data
uberon_data


Cell Type
Ontology termp-valuen
cell of skeletal muscle8.83e-079
Uber Anatomy
Ontology termp-valuen
adult organism1.44e-09115
ectoderm-derived structure2.46e-07169
organism subdivision5.64e-07365
ectoderm7.80e-07173
presumptive ectoderm7.80e-07173
anterior region of body7.82e-07129
craniocervical region7.82e-07129


Overrepresented TFBS (DNA) motifs on this co-expression clusterSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysisSummary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner

link to source dataset

data


(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
NFYA#4800313.81918552487290.0006132411806734510.00509031121191818
NFYB#4801312.56984494015230.000811456397697350.00619274349427209
SP2#6668319.61514787038350.0002171004269245340.00248724785954052



Relative expression of the co-expression clusterSummary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.
Analyst:NA

link to data source
data


This analysis result is provided for C0 - C305 clusters.