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Coexpression cluster:C3718


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Full id: C3718_CD14_Mast_Natural_Eosinophils_Basophils_CD8_CD19

Phase1 CAGE Peaks

  Short description
Hg19::chr18:3448390..3448411,+ p14@TGIF1
Hg19::chr18:3448422..3448439,+ p11@TGIF1
Hg19::chr18:3448730..3448744,+ p@chr18:3448730..3448744

Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset

No results for this coexpression

Enriched Gene Ontology terms on this co-expression clusterSummary: Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter.
Analyst: Erik Arner

link to source dataset

No GOStat results

Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset


Cell Type
Ontology termp-valuen
classical monocyte1.65e-2645
CD14-positive, CD16-negative classical monocyte1.13e-2542
myeloid leukocyte2.76e-2276
granulocyte monocyte progenitor cell5.89e-2171
myeloid lineage restricted progenitor cell7.13e-2170
macrophage dendritic cell progenitor6.94e-2065
monopoietic cell4.19e-1963
hematopoietic lineage restricted progenitor cell7.64e-18124
myeloid cell3.09e-17112
common myeloid progenitor3.09e-17112
hematopoietic stem cell3.92e-17172
angioblastic mesenchymal cell3.92e-17172
nongranular leukocyte4.63e-16119
stem cell5.46e-16444
hematopoietic oligopotent progenitor cell1.10e-15165
hematopoietic multipotent progenitor cell1.10e-15165
animal cell1.29e-15679
eukaryotic cell1.29e-15679
native cell3.96e-15722
multi fate stem cell9.68e-15430
hematopoietic cell1.08e-14182
somatic stem cell2.50e-14436
mesenchymal cell8.38e-14358
connective tissue cell2.23e-13365
motile cell5.88e-12390
somatic cell3.91e-11591
Uber Anatomy
Ontology termp-valuen
bone marrow5.32e-1980
bone element2.94e-1786
skeletal element8.15e-13101
skeletal system8.15e-13101
connective tissue1.23e-12375
hematopoietic system5.04e-12102
blood island5.04e-12102
immune system1.64e-11115
musculoskeletal system1.41e-09167
lateral plate mesoderm3.28e-09216
hemolymphoid system8.45e-09112

Overrepresented TFBS (DNA) motifs on this co-expression clusterSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs

Jaspar motifs

Novel motifs

JASPAR motifs



ENCODE TF ChIP-seq peak enrichment analysisSummary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained.
Analyst: Erik Arner

link to source dataset


No analysis results for this cluster

Relative expression of the co-expression clusterSummary:Co-expression clusters are compared against FANTOM5 samples to obtain relative expression.

link to data source

This analysis result is provided for C0 - C305 clusters.