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|ontology_enrichment_disease=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0005631!6.13e-12!14;UBERON:0000158!6.13e-12!14;UBERON:0004923!5.62e-11!57;UBERON:0002097!4.17e-09!40;UBERON:0002199!4.41e-09!45;UBERON:0002416!4.41e-09!45;UBERON:0003102!4.90e-09!95;UBERON:0003124!3.90e-07!7;UBERON:0004871!3.91e-07!8
|ontology_enrichment_uberon=UBERON:0005631!6.13e-12!14;UBERON:0000158!6.13e-12!14;UBERON:0004923!5.62e-11!57;UBERON:0002097!4.17e-09!40;UBERON:0002199!4.41e-09!45;UBERON:0002416!4.41e-09!45;UBERON:0003102!4.90e-09!95;UBERON:0003124!3.90e-07!7;UBERON:0004871!3.91e-07!8
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}}
}}

Revision as of 19:27, 8 August 2012


Full id: C3801_placenta_Fibroblast_Smooth_mesothelioma_chorionic_Olfactory_epidermoid



Phase1 CAGE Peaks

Hg19::chr19:43689230..43689259,+p@chr19:43689230..43689259
+
Hg19::chr19:43690649..43690663,-p2@PSG5
Hg19::chr19:43690679..43690695,-p1@PSG5


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
fibroblast9.60e-2175
non-terminally differentiated cell1.23e-17180
preadipocyte9.18e-1212
animal cell6.28e-11679
eukaryotic cell6.28e-11679
skin fibroblast1.54e-1023
mesothelial cell4.58e-0819
somatic cell3.03e-07591
native cell7.40e-07722
smooth muscle cell8.62e-0742
smooth muscle myoblast8.62e-0742
Uber Anatomy
Ontology termp-valuen
extraembryonic membrane6.13e-1214
membranous layer6.13e-1214
organ component layer5.62e-1157
skin of body4.17e-0940
integument4.41e-0945
integumental system4.41e-0945
surface structure4.90e-0995
chorion3.90e-077
somatic layer of lateral plate mesoderm3.91e-078


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.