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Coexpression cluster:C4101

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Full id: C4101_CD14_Eosinophils_mature_placenta_chorionic_immature_Smooth



Phase1 CAGE Peaks

Hg19::chr22:38598042..38598052,+p4@MAFF
Hg19::chr22:38598057..38598071,+p3@MAFF
Hg19::chr22:38598086..38598105,+p1@MAFF


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
vessel5.74e-1769
blood vessel2.36e-1560
epithelial tube open at both ends2.36e-1560
blood vasculature2.36e-1560
vascular cord2.36e-1560
mesoderm1.01e-14448
mesoderm-derived structure1.01e-14448
presumptive mesoderm1.01e-14448
vasculature1.84e-1479
vascular system1.84e-1479
artery5.33e-1442
arterial blood vessel5.33e-1442
arterial system5.33e-1442
splanchnic layer of lateral plate mesoderm1.01e-1384
lateral plate mesoderm1.38e-12216
systemic artery5.67e-1233
systemic arterial system5.67e-1233
epithelial tube6.10e-12118
anatomical system3.20e-11625
anatomical group4.45e-11626
cardiovascular system6.14e-10110
circulatory system1.23e-09113
multi-cellular organism3.61e-09659
musculoskeletal system6.51e-09167
germ layer4.40e-07604
embryonic tissue4.40e-07604
presumptive structure4.40e-07604
epiblast (generic)4.40e-07604
embryonic structure5.15e-07605
developing anatomical structure5.15e-07605
aorta8.44e-0721
aortic system8.44e-0721


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.