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Coexpression cluster:C4355: Difference between revisions

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|ontology_enrichment_disease=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0002049!6.55e-26!79;UBERON:0007798!6.55e-26!79;UBERON:0003081!9.48e-25!216;UBERON:0004535!5.72e-24!110;UBERON:0001009!2.60e-23!113;UBERON:0000055!3.45e-22!69;UBERON:0001981!1.58e-20!60;UBERON:0007500!1.58e-20!60;UBERON:0004537!1.58e-20!60;UBERON:0006965!1.58e-20!60;UBERON:0004872!1.85e-20!84;UBERON:0003914!2.49e-20!118;UBERON:0001637!3.10e-19!42;UBERON:0003509!3.10e-19!42;UBERON:0004572!3.10e-19!42;UBERON:0000914!8.90e-17!83;UBERON:0002329!8.90e-17!83;UBERON:0003077!8.90e-17!83;UBERON:0003059!8.90e-17!83;UBERON:0007282!8.90e-17!83;UBERON:0009618!8.90e-17!83;UBERON:0007285!8.90e-17!83;UBERON:0002204!1.22e-16!167;UBERON:0004290!3.62e-16!70;UBERON:0005256!4.70e-16!143;UBERON:0000486!1.28e-15!82;UBERON:0000926!4.02e-15!448;UBERON:0004120!4.02e-15!448;UBERON:0006603!4.02e-15!448;UBERON:0004573!6.06e-15!33;UBERON:0004571!6.06e-15!33;UBERON:0001134!8.01e-15!61;UBERON:0002036!8.01e-15!61;UBERON:0003082!8.01e-15!61;UBERON:0002385!1.43e-14!63;UBERON:0001015!1.43e-14!63;UBERON:0000383!1.43e-14!63;UBERON:0000490!3.29e-14!138;UBERON:0002100!2.18e-09!216;UBERON:0000947!7.36e-09!21;UBERON:0010191!7.36e-09!21;UBERON:0000487!4.17e-08!22;UBERON:0001986!5.14e-08!18;UBERON:0004638!5.14e-08!18;UBERON:0004852!5.14e-08!18;UBERON:0000353!6.25e-08!17;UBERON:0004211!1.98e-07!16;UBERON:0001285!1.98e-07!16;UBERON:0007684!1.98e-07!16;UBERON:0003220!1.98e-07!16;UBERON:0004208!1.98e-07!16;UBERON:0006555!3.69e-07!17;UBERON:0005103!3.69e-07!17;UBERON:0000083!3.69e-07!17;UBERON:0009201!3.69e-07!17;UBERON:0004819!3.69e-07!17;UBERON:0006553!3.69e-07!17;UBERON:0003074!3.69e-07!17;UBERON:0003060!3.69e-07!17
|ontology_enrichment_uberon=UBERON:0002049!6.55e-26!79;UBERON:0007798!6.55e-26!79;UBERON:0003081!9.48e-25!216;UBERON:0004535!5.72e-24!110;UBERON:0001009!2.60e-23!113;UBERON:0000055!3.45e-22!69;UBERON:0001981!1.58e-20!60;UBERON:0007500!1.58e-20!60;UBERON:0004537!1.58e-20!60;UBERON:0006965!1.58e-20!60;UBERON:0004872!1.85e-20!84;UBERON:0003914!2.49e-20!118;UBERON:0001637!3.10e-19!42;UBERON:0003509!3.10e-19!42;UBERON:0004572!3.10e-19!42;UBERON:0000914!8.90e-17!83;UBERON:0002329!8.90e-17!83;UBERON:0003077!8.90e-17!83;UBERON:0003059!8.90e-17!83;UBERON:0007282!8.90e-17!83;UBERON:0009618!8.90e-17!83;UBERON:0007285!8.90e-17!83;UBERON:0002204!1.22e-16!167;UBERON:0004290!3.62e-16!70;UBERON:0005256!4.70e-16!143;UBERON:0000486!1.28e-15!82;UBERON:0000926!4.02e-15!448;UBERON:0004120!4.02e-15!448;UBERON:0006603!4.02e-15!448;UBERON:0004573!6.06e-15!33;UBERON:0004571!6.06e-15!33;UBERON:0001134!8.01e-15!61;UBERON:0002036!8.01e-15!61;UBERON:0003082!8.01e-15!61;UBERON:0002385!1.43e-14!63;UBERON:0001015!1.43e-14!63;UBERON:0000383!1.43e-14!63;UBERON:0000490!3.29e-14!138;UBERON:0002100!2.18e-09!216;UBERON:0000947!7.36e-09!21;UBERON:0010191!7.36e-09!21;UBERON:0000487!4.17e-08!22;UBERON:0001986!5.14e-08!18;UBERON:0004638!5.14e-08!18;UBERON:0004852!5.14e-08!18;UBERON:0000353!6.25e-08!17;UBERON:0004211!1.98e-07!16;UBERON:0001285!1.98e-07!16;UBERON:0007684!1.98e-07!16;UBERON:0003220!1.98e-07!16;UBERON:0004208!1.98e-07!16;UBERON:0006555!3.69e-07!17;UBERON:0005103!3.69e-07!17;UBERON:0000083!3.69e-07!17;UBERON:0009201!3.69e-07!17;UBERON:0004819!3.69e-07!17;UBERON:0006553!3.69e-07!17;UBERON:0003074!3.69e-07!17;UBERON:0003060!3.69e-07!17
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}}
}}

Revision as of 19:57, 8 August 2012


Full id: C4355_Smooth_CD14_Alveolar_Astrocyte_Meningeal_Fibroblast_Renal



Phase1 CAGE Peaks

Hg19::chr4:10118348..10118395,-p1@WDR1
Hg19::chr4:10118405..10118430,-p2@WDR1
Hg19::chr4:10118443..10118454,-p4@WDR1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
somatic cell6.77e-45591
animal cell1.29e-32679
eukaryotic cell1.29e-32679
mesodermal cell1.64e-27119
non-terminally differentiated cell4.92e-25180
native cell5.00e-23722
embryonic cell6.48e-19248
contractile cell1.27e-1859
smooth muscle cell1.69e-1742
smooth muscle myoblast1.69e-1742
muscle precursor cell1.08e-1657
myoblast1.08e-1657
multi-potent skeletal muscle stem cell1.08e-1657
multi fate stem cell1.26e-16430
muscle cell1.58e-1654
somatic stem cell1.65e-16436
vascular associated smooth muscle cell4.26e-1632
stem cell2.36e-15444
electrically responsive cell5.63e-1460
electrically active cell5.63e-1460
fibroblast1.22e-1075
endothelial cell1.39e-1035
meso-epithelial cell3.11e-1044
lining cell1.66e-0957
barrier cell1.66e-0957
endothelial cell of vascular tree2.83e-0824
blood vessel endothelial cell5.14e-0818
embryonic blood vessel endothelial progenitor cell5.14e-0818
epithelial cell of nephron1.98e-0716
Uber Anatomy
Ontology termp-valuen
vasculature6.55e-2679
vascular system6.55e-2679
lateral plate mesoderm9.48e-25216
cardiovascular system5.72e-24110
circulatory system2.60e-23113
vessel3.45e-2269
blood vessel1.58e-2060
epithelial tube open at both ends1.58e-2060
blood vasculature1.58e-2060
vascular cord1.58e-2060
splanchnic layer of lateral plate mesoderm1.85e-2084
epithelial tube2.49e-20118
artery3.10e-1942
arterial blood vessel3.10e-1942
arterial system3.10e-1942
somite8.90e-1783
paraxial mesoderm8.90e-1783
presomitic mesoderm8.90e-1783
presumptive segmental plate8.90e-1783
trunk paraxial mesoderm8.90e-1783
presumptive paraxial mesoderm8.90e-1783
musculoskeletal system1.22e-16167
dermomyotome3.62e-1670
trunk mesenchyme4.70e-16143
multilaminar epithelium1.28e-1582
mesoderm4.02e-15448
mesoderm-derived structure4.02e-15448
presumptive mesoderm4.02e-15448
systemic artery6.06e-1533
systemic arterial system6.06e-1533
skeletal muscle tissue8.01e-1561
striated muscle tissue8.01e-1561
myotome8.01e-1561
muscle tissue1.43e-1463
musculature1.43e-1463
musculature of body1.43e-1463
unilaminar epithelium3.29e-14138
trunk2.18e-09216
aorta7.36e-0921
aortic system7.36e-0921
simple squamous epithelium4.17e-0822
endothelium5.14e-0818
blood vessel endothelium5.14e-0818
cardiovascular system endothelium5.14e-0818
parenchyma6.25e-0817
nephron epithelium1.98e-0716
nephron1.98e-0716
uriniferous tubule1.98e-0716
metanephric mesenchyme1.98e-0716
nephrogenic mesenchyme1.98e-0716
excretory tube3.69e-0717
mesonephric epithelium3.69e-0717
mesonephric tubule3.69e-0717
nephric duct3.69e-0717
kidney epithelium3.69e-0717
renal duct3.69e-0717
mesonephric duct3.69e-0717
pronephric duct3.69e-0717


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.