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Coexpression cluster:C933

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Full id: C933_skeletal_heart_left_penis_Cardiac_Preadipocyte_tongue



Phase1 CAGE Peaks

Hg19::chr1:78354243..78354293,+p2@NEXN
Hg19::chr1:78354297..78354320,+p1@NEXN
Hg19::chr1:78354330..78354366,+p3@NEXN
Hg19::chr1:78381736..78381749,+p@chr1:78381736..78381749
+
Hg19::chr1:78383815..78383829,+p12@NEXN
Hg19::chr1:78390864..78390882,+p@chr1:78390864..78390882
+
Hg19::chr1:78392094..78392114,+p5@NEXN
Hg19::chr1:78398956..78398980,+p6@NEXN
Hg19::chr1:78401567..78401585,+p@chr1:78401567..78401585
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
somite4.70e-1883
paraxial mesoderm4.70e-1883
presomitic mesoderm4.70e-1883
presumptive segmental plate4.70e-1883
trunk paraxial mesoderm4.70e-1883
presumptive paraxial mesoderm4.70e-1883
organism subdivision4.62e-16365
muscle tissue7.56e-1663
musculature7.56e-1663
musculature of body7.56e-1663
multi-tissue structure1.95e-15347
dermomyotome2.63e-1570
skeletal muscle tissue4.30e-1561
striated muscle tissue4.30e-1561
myotome4.30e-1561
trunk mesenchyme9.56e-15143
multi-cellular organism1.52e-14659
multilaminar epithelium1.04e-1382
mesenchyme7.57e-12238
entire embryonic mesenchyme7.57e-12238
trunk2.45e-11216
anatomical system7.32e-11625
anatomical group1.37e-10626
surface structure2.31e-1095
circulatory system1.18e-09113
primary circulatory organ3.35e-0927
cardiovascular system1.32e-08110
splanchnic layer of lateral plate mesoderm3.39e-0884
anatomical cluster3.81e-08286
cell layer4.88e-08312
unilaminar epithelium5.75e-08138
epithelium8.06e-08309
heart1.16e-0724
primitive heart tube1.16e-0724
primary heart field1.16e-0724
anterior lateral plate mesoderm1.16e-0724
heart tube1.16e-0724
heart primordium1.16e-0724
cardiac mesoderm1.16e-0724
cardiogenic plate1.16e-0724
heart rudiment1.16e-0724
compound organ1.60e-0769
embryo4.73e-07612
adult organism8.05e-07115
embryonic structure9.25e-07605
developing anatomical structure9.25e-07605


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.