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{{f5samples
{{f5samples
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|DRA_sample_Accession=CAGE@SAMD00005206
|accession_numbers=CAGE;DRX007873;DRR008745;DRZ000170;DRZ001555;DRZ011520;DRZ012905
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|ancestors_in_cell_lineage_facet=
|ancestors_in_cell_lineage_facet=
|ancestors_in_disease_facet=
|ancestors_in_disease_facet=
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100669
|comment=
|comment=
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|def=
|
|
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Line 35: Line 40:
|fonse_treatment_closure=
|fonse_treatment_closure=
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|has_quality=
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/embryonic%2520pancreas%2520cell%2520line%253a1C3D3.CNhs11732.10605-108F2.hg19.nobarcode.bam
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/embryonic%2520pancreas%2520cell%2520line%253a1C3D3.CNhs11732.10605-108F2.hg19.ctss.bed.gz
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/embryonic%2520pancreas%2520cell%2520line%253a1C3D3.CNhs11732.10605-108F2.hg19.nobarcode.rdna.fa.gz
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/embryonic%2520pancreas%2520cell%2520line%253a1C3D3.CNhs11732.10605-108F2.hg38.nobarcode.bam
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|id=FF:10605-108F2
|id=FF:10605-108F2
|is_a=EFO:0002091;;FF:0000003;;FF:0000210;;FF:0100669;;UBERON:0001264
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|library_id=CNhs11732
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|microRNAs=
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|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10605
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10605
|name=embryonic pancreas cell line:1C3D3
|name=embryonic pancreas cell line:1C3D3
|namespace=FANTOM5
|namespace=FANTOM5
Line 42: Line 59:
|profile_cagescan=,,,
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|profile_hcage=CNhs11732,LSID819,release009,COMPLETED
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|refex=http://refex.dbcls.jp/genelist.php?lang
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|rna_box=108
|rna_box=108
|rna_catalog_number=
|rna_catalog_number=
Line 57: Line 77:
|rna_weight_ug=18.19417
|rna_weight_ug=18.19417
|sample_age=19 week embryo
|sample_age=19 week embryo
|sample_category=cell lines
|sample_cell_catalog=RCB0796
|sample_cell_catalog=RCB0796
|sample_cell_line=1C3D3
|sample_cell_line=1C3D3
Line 69: Line 90:
|sample_ethnicity=J
|sample_ethnicity=J
|sample_experimental_condition=
|sample_experimental_condition=
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.77790223012464e-247!GO:0043226;organelle;1.60968718522483e-205!GO:0043231;intracellular membrane-bound organelle;3.57592846735739e-205!GO:0043229;intracellular organelle;3.8493662124164e-205!GO:0043227;membrane-bound organelle;4.96440631156462e-205!GO:0005737;cytoplasm;3.10317017835421e-175!GO:0044422;organelle part;9.57646636546742e-139!GO:0044446;intracellular organelle part;2.89014163529354e-137!GO:0044444;cytoplasmic part;1.92891108183943e-122!GO:0032991;macromolecular complex;3.88415977090374e-103!GO:0044237;cellular metabolic process;7.51438494513905e-95!GO:0044238;primary metabolic process;2.97797143033394e-93!GO:0005634;nucleus;3.39924008051649e-92!GO:0030529;ribonucleoprotein complex;3.44664843825827e-92!GO:0043170;macromolecule metabolic process;8.24869292067929e-92!GO:0003723;RNA binding;4.31543432884409e-82!GO:0044428;nuclear part;7.47051133881762e-81!GO:0043233;organelle lumen;8.77799280648777e-77!GO:0031974;membrane-enclosed lumen;8.77799280648777e-77!GO:0005515;protein binding;2.34246366969241e-68!GO:0005739;mitochondrion;1.11025130008986e-66!GO:0043283;biopolymer metabolic process;2.80306512310613e-58!GO:0006412;translation;4.94196738135474e-57!GO:0006396;RNA processing;1.19323949936492e-55!GO:0005840;ribosome;2.94122913097199e-54!GO:0010467;gene expression;3.58459267429003e-53!GO:0019538;protein metabolic process;1.0549836742524e-52!GO:0043234;protein complex;8.52311211109555e-51!GO:0016043;cellular component organization and biogenesis;2.3952834039643e-50!GO:0031981;nuclear lumen;2.72341374498494e-49!GO:0044260;cellular macromolecule metabolic process;1.66898319210884e-48!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.78870869237486e-48!GO:0044267;cellular protein metabolic process;3.15657272657134e-48!GO:0003735;structural constituent of ribosome;2.22240768387195e-47!GO:0031090;organelle membrane;1.27238178183129e-46!GO:0033036;macromolecule localization;1.26044863639329e-44!GO:0015031;protein transport;2.92386343282385e-44!GO:0044249;cellular biosynthetic process;4.34596778685581e-42!GO:0009059;macromolecule biosynthetic process;5.3925680924012e-42!GO:0044429;mitochondrial part;5.85368934991497e-42!GO:0016071;mRNA metabolic process;2.59034361538068e-41!GO:0033279;ribosomal subunit;4.25366443555795e-41!GO:0009058;biosynthetic process;6.83195742027072e-41!GO:0008104;protein localization;7.58916977697367e-41!GO:0045184;establishment of protein localization;1.14741529039974e-40!GO:0031967;organelle envelope;1.8113905767446e-40!GO:0031975;envelope;2.36157255464668e-40!GO:0008380;RNA splicing;2.91392967765886e-38!GO:0005829;cytosol;3.49686811424803e-36!GO:0006397;mRNA processing;3.56110473050453e-35!GO:0046907;intracellular transport;7.70100534355527e-35!GO:0022613;ribonucleoprotein complex biogenesis and assembly;6.93826557968302e-34!GO:0043228;non-membrane-bound organelle;9.17701045368619e-34!GO:0043232;intracellular non-membrane-bound organelle;9.17701045368619e-34!GO:0006996;organelle organization and biogenesis;1.04203837719433e-32!GO:0003676;nucleic acid binding;4.11956942762016e-31!GO:0065003;macromolecular complex assembly;1.41936119119903e-30!GO:0000166;nucleotide binding;3.01871168375033e-30!GO:0006259;DNA metabolic process;6.70899849415793e-30!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.526608095786e-29!GO:0005654;nucleoplasm;1.44683667168868e-28!GO:0006886;intracellular protein transport;1.54683477167006e-28!GO:0005681;spliceosome;1.96541408537371e-27!GO:0022607;cellular component assembly;2.14578930033561e-26!GO:0005740;mitochondrial envelope;2.1865927198775e-26!GO:0019866;organelle inner membrane;2.83819553388927e-26!GO:0016462;pyrophosphatase activity;4.78514371176002e-25!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;5.43705631289212e-25!GO:0016070;RNA metabolic process;6.04579927329721e-25!GO:0051649;establishment of cellular localization;6.08237411812341e-25!GO:0016817;hydrolase activity, acting on acid anhydrides;8.10177814727678e-25!GO:0031966;mitochondrial membrane;1.09830406806137e-24!GO:0051641;cellular localization;1.25104625571044e-24!GO:0017111;nucleoside-triphosphatase activity;1.28999065879289e-24!GO:0005743;mitochondrial inner membrane;2.07589667846486e-24!GO:0044451;nucleoplasm part;1.52890301378054e-23!GO:0005730;nucleolus;2.52089079000344e-23!GO:0044445;cytosolic part;1.17983429689676e-22!GO:0015934;large ribosomal subunit;6.716508734117e-22!GO:0032553;ribonucleotide binding;9.12948281488935e-22!GO:0032555;purine ribonucleotide binding;9.12948281488935e-22!GO:0017076;purine nucleotide binding;1.65415951293529e-21!GO:0006119;oxidative phosphorylation;4.57974092038519e-21!GO:0007049;cell cycle;1.0219500489e-20!GO:0006512;ubiquitin cycle;1.95694555274782e-20!GO:0015935;small ribosomal subunit;3.05659900928075e-20!GO:0016874;ligase activity;5.47954213703138e-20!GO:0006457;protein folding;6.00551777417037e-20!GO:0044455;mitochondrial membrane part;6.67459538363373e-19!GO:0022618;protein-RNA complex assembly;6.75198245448602e-19!GO:0008134;transcription factor binding;9.67980087429098e-19!GO:0012505;endomembrane system;1.12099485070009e-18!GO:0031980;mitochondrial lumen;1.38694059623137e-18!GO:0005759;mitochondrial matrix;1.38694059623137e-18!GO:0043285;biopolymer catabolic process;2.80296262179983e-18!GO:0044265;cellular macromolecule catabolic process;3.07249667242085e-18!GO:0051603;proteolysis involved in cellular protein catabolic process;6.34041956643201e-18!GO:0005524;ATP binding;7.7457468466652e-18!GO:0019941;modification-dependent protein catabolic process;1.20857608323669e-17!GO:0043632;modification-dependent macromolecule catabolic process;1.20857608323669e-17!GO:0032559;adenyl ribonucleotide binding;1.59151404141401e-17!GO:0044257;cellular protein catabolic process;1.96155079289025e-17!GO:0006511;ubiquitin-dependent protein catabolic process;2.51041023155079e-17!GO:0030554;adenyl nucleotide binding;3.80409815412811e-17!GO:0043412;biopolymer modification;4.35916947942732e-17!GO:0006974;response to DNA damage stimulus;8.65319127516705e-17!GO:0048770;pigment granule;1.03240900107646e-16!GO:0042470;melanosome;1.03240900107646e-16!GO:0009057;macromolecule catabolic process;1.35509878150166e-16!GO:0008135;translation factor activity, nucleic acid binding;2.21548806383482e-16!GO:0030163;protein catabolic process;5.69557832016982e-16!GO:0005746;mitochondrial respiratory chain;7.20903234610627e-16!GO:0022402;cell cycle process;8.26413041580414e-16!GO:0042254;ribosome biogenesis and assembly;8.50924737581067e-16!GO:0006366;transcription from RNA polymerase II promoter;1.2774933055842e-15!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.57941160891878e-15!GO:0006605;protein targeting;1.79658684940781e-15!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;1.8445419115506e-15!GO:0005761;mitochondrial ribosome;1.9168408778105e-15!GO:0000313;organellar ribosome;1.9168408778105e-15!GO:0000502;proteasome complex (sensu Eukaryota);2.16354052953617e-15!GO:0006464;protein modification process;7.90123457030585e-15!GO:0048193;Golgi vesicle transport;9.05523076234556e-15!GO:0005635;nuclear envelope;1.29209497100512e-14!GO:0050136;NADH dehydrogenase (quinone) activity;1.33027057478787e-14!GO:0003954;NADH dehydrogenase activity;1.33027057478787e-14!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.33027057478787e-14!GO:0051186;cofactor metabolic process;1.78110728965523e-14!GO:0006281;DNA repair;1.94925607737929e-14!GO:0051082;unfolded protein binding;2.47878986201645e-14!GO:0016887;ATPase activity;2.8609892206101e-14!GO:0031965;nuclear membrane;3.19706234655487e-14!GO:0044453;nuclear membrane part;3.72191196651088e-14!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);8.02806208116984e-14!GO:0000398;nuclear mRNA splicing, via spliceosome;8.38257087590774e-14!GO:0000375;RNA splicing, via transesterification reactions;8.38257087590774e-14!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;8.38257087590774e-14!GO:0042623;ATPase activity, coupled;9.71792413288209e-14!GO:0005783;endoplasmic reticulum;4.30724430512717e-13!GO:0043687;post-translational protein modification;5.04746683134163e-13!GO:0003712;transcription cofactor activity;6.51616467442376e-13!GO:0016192;vesicle-mediated transport;7.26756647128869e-13!GO:0042775;organelle ATP synthesis coupled electron transport;8.90904264507842e-13!GO:0042773;ATP synthesis coupled electron transport;8.90904264507842e-13!GO:0016604;nuclear body;9.1620672229309e-13!GO:0030964;NADH dehydrogenase complex (quinone);9.18777580591967e-13!GO:0045271;respiratory chain complex I;9.18777580591967e-13!GO:0005747;mitochondrial respiratory chain complex I;9.18777580591967e-13!GO:0006913;nucleocytoplasmic transport;9.72636832016614e-13!GO:0044248;cellular catabolic process;1.01548566239222e-12!GO:0006399;tRNA metabolic process;1.11432064128845e-12!GO:0005643;nuclear pore;1.44100661699085e-12!GO:0005794;Golgi apparatus;1.65212522969549e-12!GO:0005694;chromosome;1.67447049432254e-12!GO:0000278;mitotic cell cycle;1.89845297346939e-12!GO:0051169;nuclear transport;2.03917895684065e-12!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;2.77663468270697e-12!GO:0006260;DNA replication;3.82756995101749e-12!GO:0003743;translation initiation factor activity;3.8426616458127e-12!GO:0004386;helicase activity;4.65835215628728e-12!GO:0012501;programmed cell death;5.37483447015425e-12!GO:0044432;endoplasmic reticulum part;6.25674628649224e-12!GO:0006915;apoptosis;1.2628207783894e-11!GO:0051276;chromosome organization and biogenesis;1.33823852677051e-11!GO:0006732;coenzyme metabolic process;1.46568107096449e-11!GO:0008026;ATP-dependent helicase activity;1.68905034260654e-11!GO:0006413;translational initiation;2.11188749207755e-11!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;3.8372424905247e-11!GO:0006446;regulation of translational initiation;5.06481456423248e-11!GO:0009719;response to endogenous stimulus;5.38051081417185e-11!GO:0050794;regulation of cellular process;7.18354457709261e-11!GO:0008219;cell death;7.20817516627216e-11!GO:0016265;death;7.20817516627216e-11!GO:0016879;ligase activity, forming carbon-nitrogen bonds;8.08865334617131e-11!GO:0006403;RNA localization;1.67558094838687e-10!GO:0008639;small protein conjugating enzyme activity;1.86330192868825e-10!GO:0044427;chromosomal part;2.02979211816286e-10!GO:0051726;regulation of cell cycle;2.16301226642889e-10!GO:0050657;nucleic acid transport;2.28991754536812e-10!GO:0051236;establishment of RNA localization;2.28991754536812e-10!GO:0050658;RNA transport;2.28991754536812e-10!GO:0006364;rRNA processing;2.30513032705143e-10!GO:0046930;pore complex;2.45204338853801e-10!GO:0000074;regulation of progression through cell cycle;3.39639344440974e-10!GO:0004842;ubiquitin-protein ligase activity;3.45318139354255e-10!GO:0005793;ER-Golgi intermediate compartment;5.16156911370581e-10!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;6.05015266635321e-10!GO:0004812;aminoacyl-tRNA ligase activity;6.05015266635321e-10!GO:0016875;ligase activity, forming carbon-oxygen bonds;6.05015266635321e-10!GO:0016072;rRNA metabolic process;6.54516703454028e-10!GO:0065002;intracellular protein transport across a membrane;6.94183217951346e-10!GO:0016607;nuclear speck;7.24538765359054e-10!GO:0019787;small conjugating protein ligase activity;8.6262859921954e-10!GO:0017038;protein import;9.59578643008569e-10!GO:0006325;establishment and/or maintenance of chromatin architecture;1.16895642378238e-09!GO:0043038;amino acid activation;1.44706158919023e-09!GO:0006418;tRNA aminoacylation for protein translation;1.44706158919023e-09!GO:0043039;tRNA aminoacylation;1.44706158919023e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.9985177431632e-09!GO:0009259;ribonucleotide metabolic process;2.38799882401155e-09!GO:0016881;acid-amino acid ligase activity;2.54490065837576e-09!GO:0006461;protein complex assembly;3.13714351714894e-09!GO:0006163;purine nucleotide metabolic process;3.43345568923817e-09!GO:0005768;endosome;3.72846728138364e-09!GO:0008565;protein transporter activity;4.17977969668136e-09!GO:0006323;DNA packaging;4.34004195861664e-09!GO:0022403;cell cycle phase;4.5895614774006e-09!GO:0000087;M phase of mitotic cell cycle;4.8468384186635e-09!GO:0051246;regulation of protein metabolic process;4.9827784535049e-09!GO:0051301;cell division;5.1736040081437e-09!GO:0048523;negative regulation of cellular process;6.71159398013431e-09!GO:0030532;small nuclear ribonucleoprotein complex;8.0302862345368e-09!GO:0042175;nuclear envelope-endoplasmic reticulum network;8.95147636305238e-09!GO:0007067;mitosis;9.02710645247502e-09!GO:0006164;purine nucleotide biosynthetic process;9.94719321057189e-09!GO:0009260;ribonucleotide biosynthetic process;1.29896271320641e-08!GO:0003924;GTPase activity;1.43112961571007e-08!GO:0009150;purine ribonucleotide metabolic process;1.44642317996426e-08!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.56462850115754e-08!GO:0051028;mRNA transport;1.85546496835249e-08!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;2.62652443582907e-08!GO:0005789;endoplasmic reticulum membrane;2.72569466492138e-08!GO:0051188;cofactor biosynthetic process;3.23432733507638e-08!GO:0006357;regulation of transcription from RNA polymerase II promoter;3.68204758439914e-08!GO:0007005;mitochondrion organization and biogenesis;3.88461352511253e-08!GO:0009152;purine ribonucleotide biosynthetic process;4.13639160287071e-08!GO:0016740;transferase activity;5.33003035246703e-08!GO:0009055;electron carrier activity;7.57034319597201e-08!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;8.44255903297487e-08!GO:0048519;negative regulation of biological process;8.66425398799215e-08!GO:0015986;ATP synthesis coupled proton transport;1.05003290297946e-07!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.05003290297946e-07!GO:0050789;regulation of biological process;1.08974798794359e-07!GO:0015630;microtubule cytoskeleton;1.17500110038378e-07!GO:0006888;ER to Golgi vesicle-mediated transport;1.5025599510435e-07!GO:0009199;ribonucleoside triphosphate metabolic process;1.61501381735917e-07!GO:0019829;cation-transporting ATPase activity;1.91303843731199e-07!GO:0043067;regulation of programmed cell death;1.95536280549524e-07!GO:0009060;aerobic respiration;2.03412313764753e-07!GO:0042981;regulation of apoptosis;2.32676231848723e-07!GO:0009141;nucleoside triphosphate metabolic process;2.59779521924992e-07!GO:0009142;nucleoside triphosphate biosynthetic process;2.76168322718122e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;2.76168322718122e-07!GO:0016563;transcription activator activity;2.80146222840468e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;3.15386767650024e-07!GO:0009144;purine nucleoside triphosphate metabolic process;3.15386767650024e-07!GO:0000279;M phase;3.79519154851787e-07!GO:0000245;spliceosome assembly;3.84920884141108e-07!GO:0051170;nuclear import;3.96331020527539e-07!GO:0043566;structure-specific DNA binding;5.1451589394883e-07!GO:0016779;nucleotidyltransferase activity;5.17204841481236e-07!GO:0016568;chromatin modification;5.38902153001656e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;5.6041332609469e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;5.6041332609469e-07!GO:0009056;catabolic process;5.84172241028966e-07!GO:0032446;protein modification by small protein conjugation;6.09249608215392e-07!GO:0003713;transcription coactivator activity;6.54583690467563e-07!GO:0005667;transcription factor complex;7.03395818378156e-07!GO:0046034;ATP metabolic process;7.9569713680126e-07!GO:0006606;protein import into nucleus;8.37175058457787e-07!GO:0016567;protein ubiquitination;9.02320233237124e-07!GO:0006793;phosphorus metabolic process;9.62693859224855e-07!GO:0006796;phosphate metabolic process;9.62693859224855e-07!GO:0003724;RNA helicase activity;1.01363960188239e-06!GO:0009108;coenzyme biosynthetic process;1.01609231387433e-06!GO:0006754;ATP biosynthetic process;1.06926152830121e-06!GO:0006753;nucleoside phosphate metabolic process;1.06926152830121e-06!GO:0065004;protein-DNA complex assembly;1.12713378972991e-06!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;1.16024086743736e-06!GO:0007249;I-kappaB kinase/NF-kappaB cascade;1.22535628019708e-06!GO:0019222;regulation of metabolic process;1.24329165613462e-06!GO:0045259;proton-transporting ATP synthase complex;1.34367678225378e-06!GO:0000785;chromatin;1.53817541297276e-06!GO:0005813;centrosome;1.68959360885894e-06!GO:0016787;hydrolase activity;1.72273039805463e-06!GO:0005525;GTP binding;1.75085864199713e-06!GO:0031988;membrane-bound vesicle;1.82557340259985e-06!GO:0006261;DNA-dependent DNA replication;2.0637270198638e-06!GO:0016023;cytoplasmic membrane-bound vesicle;2.06442881550559e-06!GO:0016564;transcription repressor activity;2.14867059399777e-06!GO:0045333;cellular respiration;2.33604248255206e-06!GO:0005815;microtubule organizing center;2.41013172585766e-06!GO:0015078;hydrogen ion transmembrane transporter activity;2.41590604346073e-06!GO:0003899;DNA-directed RNA polymerase activity;2.54342319766473e-06!GO:0043623;cellular protein complex assembly;2.56445709368865e-06!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;2.72541433985582e-06!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;2.74694155175653e-06!GO:0044440;endosomal part;2.87725325018433e-06!GO:0010008;endosome membrane;2.87725325018433e-06!GO:0016469;proton-transporting two-sector ATPase complex;3.2086075973549e-06!GO:0005839;proteasome core complex (sensu Eukaryota);3.52622224084898e-06!GO:0005762;mitochondrial large ribosomal subunit;3.60690681853248e-06!GO:0000315;organellar large ribosomal subunit;3.60690681853248e-06!GO:0006752;group transfer coenzyme metabolic process;3.67576941113308e-06!GO:0044431;Golgi apparatus part;4.25794789417024e-06!GO:0043069;negative regulation of programmed cell death;4.66901198942858e-06!GO:0000151;ubiquitin ligase complex;4.94592177484775e-06!GO:0005770;late endosome;5.23431817117782e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;5.26632296623026e-06!GO:0016772;transferase activity, transferring phosphorus-containing groups;5.43562976226768e-06!GO:0051427;hormone receptor binding;5.67931146729138e-06!GO:0003714;transcription corepressor activity;5.8826114008406e-06!GO:0006333;chromatin assembly or disassembly;7.93489902750111e-06!GO:0006099;tricarboxylic acid cycle;9.00744339492661e-06!GO:0046356;acetyl-CoA catabolic process;9.00744339492661e-06!GO:0003697;single-stranded DNA binding;9.21179422113623e-06!GO:0008654;phospholipid biosynthetic process;1.00210421814176e-05!GO:0030120;vesicle coat;1.05040147859634e-05!GO:0030662;coated vesicle membrane;1.05040147859634e-05!GO:0031324;negative regulation of cellular metabolic process;1.1005286979682e-05!GO:0043066;negative regulation of apoptosis;1.10306348586143e-05!GO:0045786;negative regulation of progression through cell cycle;1.16452959508101e-05!GO:0035257;nuclear hormone receptor binding;1.28722905992073e-05!GO:0006084;acetyl-CoA metabolic process;1.31167571387452e-05!GO:0009117;nucleotide metabolic process;1.60690958246729e-05!GO:0005788;endoplasmic reticulum lumen;1.64963254792123e-05!GO:0006916;anti-apoptosis;1.74368711014446e-05!GO:0016310;phosphorylation;1.90287956151428e-05!GO:0004298;threonine endopeptidase activity;2.12654763339134e-05!GO:0032561;guanyl ribonucleotide binding;2.19100011482855e-05!GO:0019001;guanyl nucleotide binding;2.19100011482855e-05!GO:0031982;vesicle;2.25556395797802e-05!GO:0048475;coated membrane;2.4404224653571e-05!GO:0030117;membrane coat;2.4404224653571e-05!GO:0009109;coenzyme catabolic process;2.86408697217157e-05!GO:0031410;cytoplasmic vesicle;2.95301241697928e-05!GO:0006613;cotranslational protein targeting to membrane;3.10467039052904e-05!GO:0051187;cofactor catabolic process;3.12563070964737e-05!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;3.12563070964737e-05!GO:0005769;early endosome;3.13269176869673e-05!GO:0008186;RNA-dependent ATPase activity;3.39637951929474e-05!GO:0000314;organellar small ribosomal subunit;3.50455455391344e-05!GO:0005763;mitochondrial small ribosomal subunit;3.50455455391344e-05!GO:0048522;positive regulation of cellular process;3.70925608832923e-05!GO:0009892;negative regulation of metabolic process;3.91889631111241e-05!GO:0043021;ribonucleoprotein binding;4.10529994952944e-05!GO:0016853;isomerase activity;6.87665938057797e-05!GO:0044452;nucleolar part;6.89195899560552e-05!GO:0015077;monovalent inorganic cation transmembrane transporter activity;7.158254244603e-05!GO:0045045;secretory pathway;8.05184313537016e-05!GO:0051168;nuclear export;9.24933572059374e-05!GO:0008033;tRNA processing;0.000109512084871451!GO:0004004;ATP-dependent RNA helicase activity;0.000113461833155851!GO:0005819;spindle;0.000113640945280267!GO:0005048;signal sequence binding;0.000123920964942611!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000124329905536463!GO:0016481;negative regulation of transcription;0.000134183974960994!GO:0045454;cell redox homeostasis;0.000134225788942976!GO:0048471;perinuclear region of cytoplasm;0.000146628171558464!GO:0000139;Golgi membrane;0.000152734395590004!GO:0045893;positive regulation of transcription, DNA-dependent;0.000152734395590004!GO:0065007;biological regulation;0.000165013290666604!GO:0007243;protein kinase cascade;0.000181990907678765!GO:0019899;enzyme binding;0.000184350629476091!GO:0031252;leading edge;0.000227651578001471!GO:0031323;regulation of cellular metabolic process;0.000235235178599393!GO:0007264;small GTPase mediated signal transduction;0.000243765284066911!GO:0003690;double-stranded DNA binding;0.000250060009463264!GO:0051329;interphase of mitotic cell cycle;0.000250060009463264!GO:0045941;positive regulation of transcription;0.000250060009463264!GO:0006350;transcription;0.000267631046682501!GO:0030880;RNA polymerase complex;0.000274756582347491!GO:0006414;translational elongation;0.000291186299224145!GO:0005773;vacuole;0.000292435049786346!GO:0016859;cis-trans isomerase activity;0.000298070698684613!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.000335810628512569!GO:0051325;interphase;0.000364746354367953!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000367230278043986!GO:0030867;rough endoplasmic reticulum membrane;0.000367230278043986!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000410883042910632!GO:0005885;Arp2/3 protein complex;0.000429553571493096!GO:0006383;transcription from RNA polymerase III promoter;0.000459973898421698!GO:0051052;regulation of DNA metabolic process;0.000483592902560743!GO:0046474;glycerophospholipid biosynthetic process;0.000542960633662412!GO:0000049;tRNA binding;0.000591213978389092!GO:0016363;nuclear matrix;0.000616972478384764!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000616972478384764!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000628275680268815!GO:0004674;protein serine/threonine kinase activity;0.000638956450518335!GO:0043681;protein import into mitochondrion;0.000641805856640167!GO:0005798;Golgi-associated vesicle;0.000653556245047493!GO:0046467;membrane lipid biosynthetic process;0.000653556245047493!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.000653556245047493!GO:0015399;primary active transmembrane transporter activity;0.000653556245047493!GO:0006839;mitochondrial transport;0.000653556245047493!GO:0004576;oligosaccharyl transferase activity;0.000689574327181501!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00069970911153521!GO:0000428;DNA-directed RNA polymerase complex;0.00069970911153521!GO:0033116;ER-Golgi intermediate compartment membrane;0.000721983804649299!GO:0006402;mRNA catabolic process;0.000727947621973274!GO:0003729;mRNA binding;0.000731886793563133!GO:0019843;rRNA binding;0.000757103796141997!GO:0008250;oligosaccharyl transferase complex;0.000759665741071835!GO:0015980;energy derivation by oxidation of organic compounds;0.000769550078472139!GO:0006334;nucleosome assembly;0.000813811597950516!GO:0000059;protein import into nucleus, docking;0.000840496987616926!GO:0030036;actin cytoskeleton organization and biogenesis;0.000847515808265819!GO:0031072;heat shock protein binding;0.000878248095938332!GO:0006891;intra-Golgi vesicle-mediated transport;0.000932278519926506!GO:0065009;regulation of a molecular function;0.000962259047012943!GO:0006626;protein targeting to mitochondrion;0.000988915685898875!GO:0006401;RNA catabolic process;0.00107257326233611!GO:0008361;regulation of cell size;0.00111749348726989!GO:0008094;DNA-dependent ATPase activity;0.00113881947635466!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00119140689802042!GO:0051087;chaperone binding;0.00119810063186772!GO:0046489;phosphoinositide biosynthetic process;0.00121988861534153!GO:0003682;chromatin binding;0.00125746704485978!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.00125846979295002!GO:0006612;protein targeting to membrane;0.00126108096604989!GO:0048487;beta-tubulin binding;0.00131061361531606!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.00133202033997487!GO:0005657;replication fork;0.0013423509886928!GO:0006417;regulation of translation;0.00134358564204374!GO:0016741;transferase activity, transferring one-carbon groups;0.0013550396913688!GO:0000323;lytic vacuole;0.0014257260586628!GO:0005764;lysosome;0.0014257260586628!GO:0010468;regulation of gene expression;0.00155207907651136!GO:0008139;nuclear localization sequence binding;0.00159717694852567!GO:0051789;response to protein stimulus;0.00168619165229735!GO:0006986;response to unfolded protein;0.00168619165229735!GO:0051252;regulation of RNA metabolic process;0.00175862300222573!GO:0001558;regulation of cell growth;0.00179949184961072!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00180072276428063!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00180072276428063!GO:0007010;cytoskeleton organization and biogenesis;0.00180262597119896!GO:0006302;double-strand break repair;0.00187621211898067!GO:0031497;chromatin assembly;0.00191437419877126!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00194906067128494!GO:0005874;microtubule;0.00195272916323802!GO:0006352;transcription initiation;0.0019658918054332!GO:0009165;nucleotide biosynthetic process;0.0019679817832431!GO:0042802;identical protein binding;0.00197913989026301!GO:0007051;spindle organization and biogenesis;0.00199202527800948!GO:0016049;cell growth;0.00199868396383737!GO:0008168;methyltransferase activity;0.00202181236215357!GO:0019867;outer membrane;0.00209775759538127!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00210753677154379!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00210753677154379!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00210753677154379!GO:0005684;U2-dependent spliceosome;0.00220072496636359!GO:0003702;RNA polymerase II transcription factor activity;0.00233812762443002!GO:0003711;transcription elongation regulator activity;0.00254297273885876!GO:0015631;tubulin binding;0.00254297273885876!GO:0003678;DNA helicase activity;0.00254297273885876!GO:0016197;endosome transport;0.00267345174569944!GO:0016272;prefoldin complex;0.00269641599860554!GO:0035258;steroid hormone receptor binding;0.00285142424921647!GO:0032940;secretion by cell;0.00309411005630267!GO:0000775;chromosome, pericentric region;0.00318850503584863!GO:0048518;positive regulation of biological process;0.00326971429040799!GO:0006818;hydrogen transport;0.00331773505065863!GO:0031968;organelle outer membrane;0.0034161406849845!GO:0003684;damaged DNA binding;0.00343001321892929!GO:0048500;signal recognition particle;0.00347072508455778!GO:0032508;DNA duplex unwinding;0.0034784932231197!GO:0032392;DNA geometric change;0.0034784932231197!GO:0006091;generation of precursor metabolites and energy;0.0034793471169695!GO:0043284;biopolymer biosynthetic process;0.00350179206185054!GO:0018196;peptidyl-asparagine modification;0.00352741365385262!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.00352741365385262!GO:0031326;regulation of cellular biosynthetic process;0.0035436810217501!GO:0043492;ATPase activity, coupled to movement of substances;0.00365046715993258!GO:0006405;RNA export from nucleus;0.00371027397677554!GO:0015992;proton transport;0.00377723102939749!GO:0030029;actin filament-based process;0.00378452003466172!GO:0006289;nucleotide-excision repair;0.00380917785304602!GO:0003746;translation elongation factor activity;0.00386996962349498!GO:0031625;ubiquitin protein ligase binding;0.00396697846448924!GO:0006497;protein amino acid lipidation;0.00399820010255057!GO:0006284;base-excision repair;0.00422256123693875!GO:0006892;post-Golgi vesicle-mediated transport;0.00483519928303837!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00495762302598683!GO:0009889;regulation of biosynthetic process;0.00498052417254403!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00498052417254403!GO:0000075;cell cycle checkpoint;0.0050668841449199!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.00524979560562889!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00539915343338389!GO:0006310;DNA recombination;0.00542925771171927!GO:0030521;androgen receptor signaling pathway;0.00544275926890632!GO:0043488;regulation of mRNA stability;0.00580847323995721!GO:0043487;regulation of RNA stability;0.00580847323995721!GO:0008022;protein C-terminus binding;0.00602894542703913!GO:0043022;ribosome binding;0.00623782619176285!GO:0030132;clathrin coat of coated pit;0.00629636387284877!GO:0051101;regulation of DNA binding;0.00629636387284877!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00636612283665739!GO:0006595;polyamine metabolic process;0.00639306030515939!GO:0007006;mitochondrial membrane organization and biogenesis;0.0068737281049344!GO:0032200;telomere organization and biogenesis;0.00687828535850574!GO:0000723;telomere maintenance;0.00687828535850574!GO:0031901;early endosome membrane;0.0070921459240731!GO:0005791;rough endoplasmic reticulum;0.00710917060090593!GO:0016251;general RNA polymerase II transcription factor activity;0.00713529452917731!GO:0006611;protein export from nucleus;0.00717038816996669!GO:0008312;7S RNA binding;0.00717038816996669!GO:0033673;negative regulation of kinase activity;0.0072879138069525!GO:0006469;negative regulation of protein kinase activity;0.0072879138069525!GO:0048468;cell development;0.00756336729593412!GO:0030134;ER to Golgi transport vesicle;0.00839942248493471!GO:0045892;negative regulation of transcription, DNA-dependent;0.00841183926404662!GO:0017166;vinculin binding;0.00844421464727263!GO:0031902;late endosome membrane;0.00849542070160528!GO:0005741;mitochondrial outer membrane;0.00849664611508701!GO:0006672;ceramide metabolic process;0.00853771026562948!GO:0046966;thyroid hormone receptor binding;0.00855474282654387!GO:0005637;nuclear inner membrane;0.00869089694845143!GO:0032774;RNA biosynthetic process;0.00871430424387653!GO:0000776;kinetochore;0.00887721370686857!GO:0006275;regulation of DNA replication;0.00887724812345647!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.00894815323782809!GO:0046483;heterocycle metabolic process;0.00896802598810042!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00915862956846261!GO:0006351;transcription, DNA-dependent;0.00971421637298327!GO:0006268;DNA unwinding during replication;0.0099624039376554!GO:0005905;coated pit;0.0101740764037138!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0101905592475351!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0101986949696864!GO:0045047;protein targeting to ER;0.0101986949696864!GO:0030176;integral to endoplasmic reticulum membrane;0.0102574603612967!GO:0007050;cell cycle arrest;0.010646660633332!GO:0006607;NLS-bearing substrate import into nucleus;0.0108503520101152!GO:0008047;enzyme activator activity;0.0109593330639461!GO:0005832;chaperonin-containing T-complex;0.0110008218188136!GO:0051348;negative regulation of transferase activity;0.0110195540928338!GO:0040008;regulation of growth;0.0112095608258081!GO:0000339;RNA cap binding;0.0115031043154235!GO:0046822;regulation of nucleocytoplasmic transport;0.0116215903650034!GO:0008632;apoptotic program;0.0116215903650034!GO:0046983;protein dimerization activity;0.0120603518534826!GO:0022890;inorganic cation transmembrane transporter activity;0.0122710042906276!GO:0046519;sphingoid metabolic process;0.0124404943159857!GO:0006506;GPI anchor biosynthetic process;0.0125621367828286!GO:0030133;transport vesicle;0.0125621367828286!GO:0016791;phosphoric monoester hydrolase activity;0.0125621367828286!GO:0051098;regulation of binding;0.012739234126907!GO:0000287;magnesium ion binding;0.0128192933925609!GO:0008287;protein serine/threonine phosphatase complex;0.0132369830828321!GO:0004527;exonuclease activity;0.0132444836841337!GO:0000082;G1/S transition of mitotic cell cycle;0.0132853986221239!GO:0030518;steroid hormone receptor signaling pathway;0.0134543360412127!GO:0009893;positive regulation of metabolic process;0.0136968452964613!GO:0006376;mRNA splice site selection;0.0137582413966723!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0137582413966723!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0138375690404664!GO:0042158;lipoprotein biosynthetic process;0.0138658110899288!GO:0004518;nuclease activity;0.0139033012372611!GO:0016311;dephosphorylation;0.0139922193939535!GO:0006505;GPI anchor metabolic process;0.014377380500188!GO:0043624;cellular protein complex disassembly;0.0152402334514978!GO:0016044;membrane organization and biogenesis;0.0152402334514978!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.0158210623990092!GO:0009967;positive regulation of signal transduction;0.0162486641947181!GO:0030127;COPII vesicle coat;0.0164322656739733!GO:0012507;ER to Golgi transport vesicle membrane;0.0164322656739733!GO:0050681;androgen receptor binding;0.0164524586611855!GO:0016491;oxidoreductase activity;0.0165775959144554!GO:0030658;transport vesicle membrane;0.0165816782345791!GO:0004532;exoribonuclease activity;0.0167960552740335!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0167960552740335!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0170107522700073!GO:0015002;heme-copper terminal oxidase activity;0.0170107522700073!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0170107522700073!GO:0004129;cytochrome-c oxidase activity;0.0170107522700073!GO:0006144;purine base metabolic process;0.0170182598330405!GO:0050662;coenzyme binding;0.017392224640115!GO:0008234;cysteine-type peptidase activity;0.017392497867834!GO:0007030;Golgi organization and biogenesis;0.0182585578027635!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0183242928949646!GO:0007040;lysosome organization and biogenesis;0.018368588947289!GO:0007088;regulation of mitosis;0.0188112253285337!GO:0004722;protein serine/threonine phosphatase activity;0.0188898944181067!GO:0030663;COPI coated vesicle membrane;0.0190457847404993!GO:0030126;COPI vesicle coat;0.0190457847404993!GO:0007242;intracellular signaling cascade;0.0194841848874464!GO:0051539;4 iron, 4 sulfur cluster binding;0.0196104815269507!GO:0030027;lamellipodium;0.0198639302407252!GO:0009451;RNA modification;0.0199988017046909!GO:0006650;glycerophospholipid metabolic process;0.0210327308988881!GO:0009116;nucleoside metabolic process;0.0215749616815907!GO:0030118;clathrin coat;0.0217020915252353!GO:0000781;chromosome, telomeric region;0.0217020915252353!GO:0000922;spindle pole;0.0221725533168812!GO:0006740;NADPH regeneration;0.0222780625266865!GO:0006098;pentose-phosphate shunt;0.0222780625266865!GO:0030137;COPI-coated vesicle;0.0223453599716642!GO:0009112;nucleobase metabolic process;0.0224735247367539!GO:0005732;small nucleolar ribonucleoprotein complex;0.0228384713124235!GO:0008017;microtubule binding;0.0235786825779298!GO:0022406;membrane docking;0.0242491667275218!GO:0048278;vesicle docking;0.0242491667275218!GO:0031529;ruffle organization and biogenesis;0.0243131822644428!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0243800708273692!GO:0032984;macromolecular complex disassembly;0.0244746472680642!GO:0006338;chromatin remodeling;0.0245039025317101!GO:0031970;organelle envelope lumen;0.0246440771651968!GO:0009303;rRNA transcription;0.0248209704338333!GO:0022415;viral reproductive process;0.0248350995189062!GO:0008637;apoptotic mitochondrial changes;0.0251090680018108!GO:0005869;dynactin complex;0.0251423587630228!GO:0007004;telomere maintenance via telomerase;0.0252068028194488!GO:0031124;mRNA 3'-end processing;0.0258723992427609!GO:0007052;mitotic spindle organization and biogenesis;0.026257807026731!GO:0004721;phosphoprotein phosphatase activity;0.0263494875852663!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.0263910903628857!GO:0007265;Ras protein signal transduction;0.0264853328767351!GO:0030660;Golgi-associated vesicle membrane;0.026587626099715!GO:0030659;cytoplasmic vesicle membrane;0.026587626099715!GO:0032507;maintenance of cellular protein localization;0.0271996988807732!GO:0003725;double-stranded RNA binding;0.0272196555954841!GO:0035035;histone acetyltransferase binding;0.0272448193725987!GO:0050790;regulation of catalytic activity;0.0276598769797362!GO:0005862;muscle thin filament tropomyosin;0.0282894783460963!GO:0008629;induction of apoptosis by intracellular signals;0.0289501391441424!GO:0050178;phenylpyruvate tautomerase activity;0.0291370524417267!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.0293624051736205!GO:0043065;positive regulation of apoptosis;0.0293922602795663!GO:0005758;mitochondrial intermembrane space;0.0295235513513286!GO:0000178;exosome (RNase complex);0.0295235513513286!GO:0007041;lysosomal transport;0.0299187482218146!GO:0006950;response to stress;0.0300054581831071!GO:0007034;vacuolar transport;0.0302029527185256!GO:0019783;small conjugating protein-specific protease activity;0.0306274927569015!GO:0051540;metal cluster binding;0.0313483914652134!GO:0051536;iron-sulfur cluster binding;0.0313483914652134!GO:0005853;eukaryotic translation elongation factor 1 complex;0.0318224405239377!GO:0009124;nucleoside monophosphate biosynthetic process;0.0320317704528543!GO:0009123;nucleoside monophosphate metabolic process;0.0320317704528543!GO:0045792;negative regulation of cell size;0.0322605707963157!GO:0044433;cytoplasmic vesicle part;0.0323438638230644!GO:0006541;glutamine metabolic process;0.0324160509402535!GO:0005669;transcription factor TFIID complex;0.0327636240177796!GO:0030503;regulation of cell redox homeostasis;0.0329240716681974!GO:0016301;kinase activity;0.0333043872639004!GO:0000123;histone acetyltransferase complex;0.033571718138361!GO:0008538;proteasome activator activity;0.0343987329690199!GO:0001726;ruffle;0.0345584390235094!GO:0016407;acetyltransferase activity;0.0347402481126609!GO:0051128;regulation of cellular component organization and biogenesis;0.0353815192118828!GO:0031461;cullin-RING ubiquitin ligase complex;0.0357452248804937!GO:0045944;positive regulation of transcription from RNA polymerase II promoter;0.0358527953937287!GO:0004680;casein kinase activity;0.0359534455186916!GO:0043068;positive regulation of programmed cell death;0.036520582500159!GO:0043241;protein complex disassembly;0.0366854670064986!GO:0045449;regulation of transcription;0.0368219924852539!GO:0008610;lipid biosynthetic process;0.0370320716353484!GO:0044262;cellular carbohydrate metabolic process;0.0371917511039446!GO:0016126;sterol biosynthetic process;0.0372728969634698!GO:0008097;5S rRNA binding;0.0373383089190248!GO:0006904;vesicle docking during exocytosis;0.037428925758049!GO:0050811;GABA receptor binding;0.037428925758049!GO:0000096;sulfur amino acid metabolic process;0.0374923867252523!GO:0006458;'de novo' protein folding;0.0374923867252523!GO:0051084;'de novo' posttranslational protein folding;0.0374923867252523!GO:0043189;H4/H2A histone acetyltransferase complex;0.0378042364656866!GO:0006354;RNA elongation;0.0379993712158595!GO:0004177;aminopeptidase activity;0.0380223759836825!GO:0006984;ER-nuclear signaling pathway;0.0383388063058854!GO:0051287;NAD binding;0.0383388063058854!GO:0008092;cytoskeletal protein binding;0.0386536737991054!GO:0006360;transcription from RNA polymerase I promoter;0.0387050520946038!GO:0005774;vacuolar membrane;0.0388864002155996!GO:0042770;DNA damage response, signal transduction;0.0388864002155996!GO:0043433;negative regulation of transcription factor activity;0.0390137437531382!GO:0007017;microtubule-based process;0.0390137437531382!GO:0045185;maintenance of protein localization;0.0390137437531382!GO:0030308;negative regulation of cell growth;0.0394358884503977!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0395786976046517!GO:0031325;positive regulation of cellular metabolic process;0.0395786976046517!GO:0000786;nucleosome;0.0395786976046517!GO:0007033;vacuole organization and biogenesis;0.0395786976046517!GO:0047485;protein N-terminus binding;0.0407760070891353!GO:0030041;actin filament polymerization;0.0410471444269804!GO:0004843;ubiquitin-specific protease activity;0.041355900780099!GO:0051045;negative regulation of membrane protein ectodomain proteolysis;0.0417327462762983!GO:0051043;regulation of membrane protein ectodomain proteolysis;0.0417327462762983!GO:0004003;ATP-dependent DNA helicase activity;0.0417327462762983!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.0422483149178515!GO:0007021;tubulin folding;0.0422483149178515!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0423231386783549!GO:0043407;negative regulation of MAP kinase activity;0.042716587456519!GO:0006778;porphyrin metabolic process;0.042716587456519!GO:0033013;tetrapyrrole metabolic process;0.042716587456519!GO:0030384;phosphoinositide metabolic process;0.0427215076415126!GO:0048144;fibroblast proliferation;0.0428112148545001!GO:0048145;regulation of fibroblast proliferation;0.0428112148545001!GO:0046112;nucleobase biosynthetic process;0.0428482574529492!GO:0032906;transforming growth factor-beta2 production;0.0429001055149293!GO:0032909;regulation of transforming growth factor-beta2 production;0.0429001055149293!GO:0030522;intracellular receptor-mediated signaling pathway;0.0429236195673311!GO:0016790;thiolester hydrolase activity;0.0429902562553814!GO:0032259;methylation;0.0430128084074487!GO:0008180;signalosome;0.0434931740548916!GO:0006695;cholesterol biosynthetic process;0.0435138322053238!GO:0012506;vesicle membrane;0.0435825457999951!GO:0007093;mitotic cell cycle checkpoint;0.0441512321499916!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0446603951986986!GO:0048037;cofactor binding;0.0461435421435199!GO:0019206;nucleoside kinase activity;0.0463011349448227!GO:0031123;RNA 3'-end processing;0.0463011349448227!GO:0030911;TPR domain binding;0.0465507085320169!GO:0006520;amino acid metabolic process;0.0466478988308081!GO:0006278;RNA-dependent DNA replication;0.0469542968191288!GO:0051651;maintenance of cellular localization;0.0470644541883175!GO:0005876;spindle microtubule;0.048396669849294!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0484716387337655!GO:0005784;translocon complex;0.0488478466027955!GO:0005096;GTPase activator activity;0.0488478466027955!GO:0006400;tRNA modification;0.0493990047564875
|sample_id=10605
|sample_id=10605
|sample_note=
|sample_note=
Line 76: Line 98:
|sample_tissue=pancreas
|sample_tissue=pancreas
|top_motifs=FOXQ1:1.54459981527;PAX8:1.45506634335;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.40712202769;AIRE:1.39584197241;ONECUT1,2:1.39430490845;bHLH_family:1.15132533595;HES1:1.13289131545;POU1F1:0.857624543612;NKX2-2,8:0.836058067713;PAX1,9:0.726050056738;TEF:0.720153625458;ARID5B:0.651894750508;HOX{A6,A7,B6,B7}:0.586385682177;POU6F1:0.572940008774;PPARG:0.534872416862;ALX1:0.530781363729;FOX{I1,J2}:0.528420995239;RORA:0.514868136631;PITX1..3:0.489218646632;PAX3,7:0.417042051898;ZFP161:0.411535442984;ADNP_IRX_SIX_ZHX:0.394736961461;PAX4:0.386525479967;BPTF:0.384682651804;NRF1:0.369205735254;NFE2L2:0.35428982357;NFIX:0.340572167685;YY1:0.336493470761;GTF2A1,2:0.330833008024;CDC5L:0.329635033236;ZBTB16:0.301411830407;PRRX1,2:0.294205632352;ZNF143:0.292692884459;CEBPA,B_DDIT3:0.292409477593;FOS_FOS{B,L1}_JUN{B,D}:0.288716569718;PBX1:0.267429648775;MYB:0.257840993848;HOX{A4,D4}:0.257075821906;GLI1..3:0.25400785985;AHR_ARNT_ARNT2:0.245349143505;VSX1,2:0.242684125564;ELK1,4_GABP{A,B1}:0.241424323439;NFE2:0.231185323417;EGR1..3:0.200929230991;RFX1:0.194916688362;HOX{A5,B5}:0.194013587564;HOXA9_MEIS1:0.156943351117;RXR{A,B,G}:0.156482404429;TLX1..3_NFIC{dimer}:0.144460263525;TEAD1:0.136454592241;TFAP2B:0.133678410199;TP53:0.130230452843;BACH2:0.129228466184;SP1:0.113755178471;STAT5{A,B}:0.111192680784;E2F1..5:0.110242824394;FOX{D1,D2}:0.100981643021;XCPE1{core}:0.0981840487818;NFKB1_REL_RELA:0.0963353133825;HIC1:0.0937883853746;REST:0.0790155482217;UFEwm:0.0529296163779;FOSL2:0.0525940819744;HNF1A:0.04990587913;FOXP1:0.0477942476161;NANOG:0.0427829998121;ZIC1..3:0.0421014107689;LMO2:0.0373867085264;ATF4:0.0174830990065;NR5A1,2:0.0122031718658;CDX1,2,4:0.0104189816852;CUX2:0.0086723965042;ZNF423:0.00651932021975;NR3C1:-0.0127869435271;LEF1_TCF7_TCF7L1,2:-0.0172069172034;TBX4,5:-0.0298671974877;ZBTB6:-0.0319600162821;NFE2L1:-0.0373430308586;FOXA2:-0.0520869194271;EVI1:-0.0646703671002;TFAP2{A,C}:-0.0744031666484;FOXD3:-0.0796641248663;FOX{F1,F2,J1}:-0.0812975679604;SOX17:-0.0862975941333;ZNF148:-0.0904256084697;TFDP1:-0.0936119402806;POU2F1..3:-0.1063544797;NKX2-1,4:-0.107377346893;RBPJ:-0.110338456192;ALX4:-0.112230021804;NKX6-1,2:-0.121762082241;POU3F1..4:-0.122248915868;TOPORS:-0.123247927809;CRX:-0.128532061447;SOX5:-0.134487639671;PAX5:-0.136436908081;PDX1:-0.13836938986;IKZF2:-0.141919569585;MYOD1:-0.146009418608;SNAI1..3:-0.146438111362;FOXM1:-0.151084352454;HNF4A_NR2F1,2:-0.15279030363;BREu{core}:-0.176915374991;NKX3-2:-0.177879634169;T:-0.180849047475;ATF2:-0.193210685171;ELF1,2,4:-0.193545683926;HLF:-0.201088975441;NR1H4:-0.212168199295;ZNF384:-0.213034944452;NFIL3:-0.217785364021;ZEB1:-0.220812623891;EBF1:-0.22158725574;HSF1,2:-0.22234133777;PATZ1:-0.224780918901;HBP1_HMGB_SSRP1_UBTF:-0.24532977899;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.246257715418;NKX3-1:-0.248798433752;ESRRA:-0.256232263163;RFX2..5_RFXANK_RFXAP:-0.264476469249;MEF2{A,B,C,D}:-0.265601712389;POU5F1:-0.267013504627;HMGA1,2:-0.269410808816;ETS1,2:-0.271630857149;GATA6:-0.275161770612;EN1,2:-0.275740751456;DMAP1_NCOR{1,2}_SMARC:-0.278777372446;MED-1{core}:-0.286735599366;PAX2:-0.290076458386;ESR1:-0.305066235078;IKZF1:-0.30541283067;RXRA_VDR{dimer}:-0.311447980474;SRF:-0.324887439239;SOX2:-0.327189082826;FOXL1:-0.333379901896;ATF5_CREB3:-0.334288826558;SPIB:-0.342788491863;STAT2,4,6:-0.349883344141;IRF7:-0.357647864256;PRDM1:-0.362083149515;MYBL2:-0.371321942241;SOX{8,9,10}:-0.376058850919;NFY{A,B,C}:-0.377565144882;LHX3,4:-0.388646024114;OCT4_SOX2{dimer}:-0.391868605251;GTF2I:-0.410030072814;GFI1B:-0.438230602045;CREB1:-0.438943599491;SPI1:-0.446697746173;TAL1_TCF{3,4,12}:-0.450857753416;GZF1:-0.464446488737;MTF1:-0.467946951193;NFATC1..3:-0.478778140226;NHLH1,2:-0.522992381909;RUNX1..3:-0.526777960393;TFCP2:-0.537902843151;NR6A1:-0.572872201101;MTE{core}:-0.574106801219;JUN:-0.616910927165;IRF1,2:-0.661901019854;FOXN1:-0.685264535692;MYFfamily:-0.686345350824;HIF1A:-0.712970017231;SMAD1..7,9:-0.725936832689;MAZ:-0.73290979899;FOXO1,3,4:-0.736263657814;XBP1:-0.741851091355;AR:-0.746837535132;KLF4:-0.751182650786;STAT1,3:-0.771451074684;RREB1:-0.77440655871;DBP:-0.787685124009;GATA4:-0.806995806043;GFI1:-0.815672618203;TLX2:-0.816563544526;PAX6:-0.830650929839;TFAP4:-0.835600056056;NKX2-3_NKX2-5:-0.838642874282;ATF6:-0.853656494345;SPZ1:-0.860626005595;HAND1,2:-0.868595442021;MZF1:-0.916868840853;TBP:-0.97031842527;FOXP3:-0.995282915884;SREBF1,2:-1.00698148826;GCM1,2:-1.06526298851;HMX1:-1.06982806663;EP300:-1.10182610362;MAFB:-1.15110898082;ZNF238:-1.26412345929;NANOG{mouse}:-1.32799405421;TGIF1:-1.39941397783
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|xref=
}}
}}

Revision as of 19:32, 10 August 2017

Name:embryonic pancreas cell line:1C3D3
Species:Human (Homo sapiens)
Library ID:CNhs11732
Sample type:cell lines
Genomic View: UCSC
RefEX:Specific genes
CAGEd-oPOSSUM:link
Additional information
Sample information
strainNA
tissuepancreas
dev stageNA
sexunknown
age19 week embryo
cell typeunclassifiable
cell line1C3D3
companyRIKEN Bioresource centre
collaborationYukio Nakamura (RIKEN BRC)
External link for information[{{{sample_info_link}}} {{{sample_info_link}}}]
RNA information
lot numberNA
catalog numberNA
sample typetotal RNA
extraction protocol (Details)OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0

CAGE Accession numbers
MethodSample accession id
CAGE  SAMD00005206
Library accession numbers

Library idMethodExp. accession idRun accession id
CNhs11732 CAGE DRX007873 DRR008745
Accession ID Hg19

Library idBAMCTSS
CNhs11732 DRZ000170 DRZ001555
Accession ID Hg38

Library idBAMCTSS
CNhs11732 DRZ011520 DRZ012905
Download raw sequence, BAM & CTSS
Hg19
FastaBAMCTSS
downloaddownloaddonwload
Hg38
BAMCTSS
downloaddonwload


Relative expression to median (log10)


Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.



Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data

Coexpression clusterscore
C0-CD14-Eosinophils-Neutrophils-Basophils-CD34-immature-Peripheral0
C1-testis-epididymis-embryonic-medulla-pituitary-trachea-caudate0
C10-occipital-temporal-parietal-brain-duodenum-Neurons-Neural0
C100-rhabdomyosarcoma-gastric-pineal-Wilms-cervical-mesodermal-endometrial0
C101-small-cerebellum-maxillary-colon-parietal-epididymis-merkel0
C102-neuroblastoma-testicular-pituitary-carcinosarcoma-rectum-acantholytic-iPS0
C103-CD4-CD8-Natural-Peripheral-Whole-Neutrophils-Basophils0
C104-Mast-Basophils-immature-CD14-CD34-eye-Natural0
C105-heart-skeletal-occipital-hippocampus-acute-Sebocyte-penis0.0156
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C89-small-retinoblastoma-medulloblastoma-iPS-acantholytic-eye-bronchogenic0
C9-skeletal-diaphragm-tongue-throat-penis-heart-left0
C90-neuroectodermal-peripheral-neuroepithelioma-neuroblastoma-carcinoid-parietal-putamen0
C91-Fibroblast-Smooth-mesenchymal-Mesothelial-Small-Preadipocyte-Hair0
C92-CD14CD16-CD14-Eosinophils-Basophils-Neutrophils-Macrophage-Whole0
C93-chronic-acute-leukemia-acantholytic-medulloblastoma-testis-papillotubular0
C94-smallcell-adrenal-lung-nonsmall-small-somatostatinoma-teratocarcinoma0
C95-lung-aorta-trachea-penis-Alveolar-throat-endometrioid0
C96-non-acute-tonsil-spleen-Burkitt-lymphoma-appendix0
C97-small-smallcell-gastrointestinal-argyrophil-putamen-duodenum-brain0
C98-CD8-Natural-Basophils-blood-CD4-Peripheral-Whole0
C99-hairy-mycosis-submaxillary-salivary-cord-kidney-parotid0



Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data



TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample


JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs11732

Jaspar motifP-value
MA0002.20.519
MA0003.10.605
MA0004.10.0431
MA0006.10.919
MA0007.10.0993
MA0009.10.69
MA0014.10.25
MA0017.10.963
MA0018.20.111
MA0019.10.994
MA0024.10.934
MA0025.10.342
MA0027.10.635
MA0028.10.00944
MA0029.10.363
MA0030.10.0957
MA0031.10.589
MA0035.20.152
MA0038.10.185
MA0039.20.0132
MA0040.10.389
MA0041.10.501
MA0042.10.825
MA0043.10.137
MA0046.10.655
MA0047.20.153
MA0048.10.00643
MA0050.13.55894e-5
MA0051.10.504
MA0052.10.449
MA0055.13.9696e-5
MA0057.10.799
MA0058.10.203
MA0059.10.0385
MA0060.10.023
MA0061.10.31
MA0062.20.229
MA0065.20.0138
MA0066.10.964
MA0067.10.409
MA0068.10.0218
MA0069.10.824
MA0070.10.91
MA0071.10.153
MA0072.10.633
MA0073.10.696
MA0074.10.823
MA0076.10.14
MA0077.10.231
MA0078.10.56
MA0079.20.983
MA0080.21.414e-5
MA0081.10.196
MA0083.10.17
MA0084.10.749
MA0087.10.941
MA0088.10.044
MA0090.10.409
MA0091.10.0218
MA0092.10.0657
MA0093.10.041
MA0099.21.89421e-6
MA0100.10.987
MA0101.10.0199
MA0102.20.0395
MA0103.10.348
MA0104.20.00717
MA0105.10.944
MA0106.10.83
MA0107.10.128
MA0108.23.59254e-4
MA0111.10.385
MA0112.20.926
MA0113.10.433
MA0114.10.0378
MA0115.10.483
MA0116.10.451
MA0117.10.0647
MA0119.10.167
MA0122.10.367
MA0124.10.177
MA0125.10.558
MA0131.10.329
MA0135.10.0751
MA0136.10.00624
MA0137.20.125
MA0138.20.813
MA0139.10.0777
MA0140.10.0977
MA0141.10.129
MA0142.10.0538
MA0143.10.897
MA0144.10.559
MA0145.10.302
MA0146.10.519
MA0147.17.01999e-4
MA0148.10.0173
MA0149.10.0152
MA0150.10.583
MA0152.10.619
MA0153.10.48
MA0154.10.428
MA0155.10.394
MA0156.10.798
MA0157.10.672
MA0159.10.0515
MA0160.10.682
MA0162.10.746
MA0163.10.892
MA0164.10.203
MA0258.10.865
MA0259.10.0627



FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs11732

Novel motifP-value
10.579
100.292
1000.278
1010.891
1020.128
1030.121
1040.449
1050.891
1060.00278
1070.564
1080.869
1090.0174
110.547
1100.719
1110.114
1120.446
1130.0437
1140.646
1150.871
1160.845
1170.0779
1180.342
1190.0845
120.287
1200.163
1210.493
1220.948
1230.363
1240.237
1250.768
1260.667
1270.716
1280.0382
1290.219
130.114
1300.673
1310.105
1320.677
1330.109
1340.0438
1350.0191
1360.118
1370.334
1380.583
1390.542
140.715
1400.74
1410.829
1420.266
1430.458
1440.914
1450.136
1460.697
1470.054
1480.68
1490.11
150.0264
1500.978
1510.991
1520.817
1530.438
1540.506
1550.179
1560.598
1570.866
1580.129
1590.225
160.854
1600.831
1610.295
1620.802
1630.588
1640.611
1650.536
1660.324
1670.145
1680.985
1690.573
170.47
180.779
190.179
20.0436
200.00712
210.256
220.503
230.465
240.873
250.195
260.409
270.106
280.554
290.694
30.43
300.131
310.336
320.085
330.937
340.642
350.706
360.0852
370.642
380.497
390.846
40.988
400.0278
410.247
420.174
430.782
440.909
450.675
460.696
470.623
480.454
490.729
50.713
500.175
510.857
520.0316
530.341
540.909
550.448
560.416
570.251
580.518
590.143
60.536
600.0982
610.042
620.226
630.286
640.661
650.936
660.122
670.298
680.887
690.569
70.591
700.0593
710.85
720.104
730.618
740.472
750.199
760.0726
770.739
780.8
790.648
80.608
800.642
810.0985
820.504
830.572
840.791
850.834
860.437
870.103
880.822
890.0333
90.399
900.145
910.128
920.413
930.0195
940.631
950.147
960.272
970.761
980.371
990.229



de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br> library id: CNhs11732


FANTOM5 (FF) ontology


Direct parent terms


Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data

UBERON: Anatomy
0000468 (multi-cellular organism)
0000922 (embryo)
0001264 (pancreas)
0002100 (trunk)
0000466 (immaterial anatomical entity)
0002075 (viscus)
0000062 (organ)
0000475 (organism subdivision)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0002553 (anatomical cavity)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0002323 (body cavity)
0005177 (trunk region element)
0000464 (anatomical space)
0004458 (body cavity or lining)
0000949 (endocrine system)

FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100669 (embryonic cell line sample)

Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
NA