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{{f5samples
{{f5samples
|id=FF:10766-110F1
|DRA_sample_Accession=CAGE@SAMD00004724
|name=chronic myelogenous leukemia (CML) cell line:MEG-A2
|accession_numbers=CAGE;DRX007854;DRR008726;DRZ000151;DRZ001536;DRZ011501;DRZ012886
|sample_id=10766
|ancestors_in_anatomy_facet=
|rna_tube_id=110F1
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000255
|rna_box=110
|ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:2531,DOID:14566,DOID:0060083,DOID:1240,DOID:8692,DOID:8552
|rna_position=F1
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100737,FF:0101035,FF:0100740
|sample_cell_lot=
|comment=
|sample_cell_catalog=ifo50478
|created_by=
|sample_company=JAPAN HEALTH SCIENCES FOUNDATION - Health Science Research Resources Bank
|creation_date=
|rna_lot_number=
|data_phase=2
|rna_catalog_number=
|datafreeze_phase=2
|sample_species=Human (Homo sapiens)
|def=
|sample_strain=
|expression_enrichment_score=chr3:128212033..128212051,-!p1@GATA2!2.64!432.15!GATA2;;chrX:48644984..48645005,+!p1@GATA1!2.27!184.33!GATA1;;chr12:54694758..54694805,-!p1@NFE2!2.21!193.80!NFE2;;chr6:135502501..135502546,+!p1@MYB!2.21!191.64!MYB;;chr19:12998003..12998021,-!p1@KLF1!2.06!115.02!KLF1;;chr12:54694807..54694832,-!p3@NFE2!1.99!95.90!NFE2;;chr9:135854091..135854159,+!p1@GFI1B!1.94!86.76!GFI1B;;chr3:128206762..128206781,-!p2@GATA2!1.81!378.63!GATA2;;chr19:13213511..13213545,-!p2@LYL1!1.78!63.49!LYL1;;chr6:135502408..135502459,+!p2@MYB!1.70!56.35!MYB;;chr5:134369905..134369972,-!p1@PITX1!1.55!52.52!PITX1;;chr21:39870339..39870443,-!p1@ERG!1.55!34.41!ERG;;chr6:135502472..135502489,+!p3@MYB!1.54!33.74!MYB;;chr12:54785074..54785122,-!p2@ZNF385A!1.53!50.36!ZNF385A;;chr5:134369879..134369898,-!p2@PITX1!1.50!30.42!PITX1;;chr10:94449703..94449718,+!p1@HHEX!1.46!104.38!HHEX;;chr11:47400045..47400060,-!p6@SPI1!1.42!25.43!SPI1;;chr9:20382446..20382493,-!p4@MLLT3!1.41!24.43!MLLT3;;chr7:50344289..50344323,+!p1@IKZF1!1.39!23.27!IKZF1;;chr12:54785054..54785072,-!p4@ZNF385A!1.38!26.26!ZNF385A;;chr11:47400078..47400106,-!p1@SPI1!1.38!23.10!SPI1;;chr11:47399996..47400014,-!p4@SPI1!1.38!22.94!SPI1;;chr11:47399947..47399961,-!p3@SPI1!1.36!21.94!SPI1;;chr7:137620650..137620677,-!p3@CREB3L2!1.33!20.28!CREB3L2;;chr19:13213399..13213414,-!p6@LYL1!1.30!18.95!LYL1;;chr20:50159198..50159299,-!p1@NFATC2!1.29!27.09!NFATC2;;chr1:47695003..47695042,-!p2@TAL1!1.27!17.62!TAL1;;chr17:40441354..40441410,+!p2@STAT5A!1.27!17.62!STAT5A;;chr11:47400032..47400043,-!p5@SPI1!1.26!17.29!SPI1;;chr8:37963466..37963506,+!p3@ASH2L!1.25!21.11!ASH2L;;chr12:54689532..54689551,-!p4@NFE2!1.25!16.79!NFE2;;chr1:47691303..47691319,-!p5@TAL1!1.24!16.45!TAL1;;chr7:137620684..137620711,-!p4@CREB3L2!1.24!16.29!CREB3L2;;chr2:68592406..68592424,+!p1@PLEK!1.23!15.79!PLEK;;chrY:21906594..21906622,-!p1@KDM5D!1.22!15.62!KDM5D;;chr12:54694653..54694672,-!p2@NFE2!1.22!15.62!NFE2;;chr19:13213555..13213568,-!p5@LYL1!1.21!15.29!LYL1;;chr1:47697881..47697910,-!p4@TAL1!1.21!15.13!TAL1;;chr19:33793430..33793447,-!p1@CEBPA!1.17!57.34!CEBPA;;chr4:109089095..109089144,-!p6@LEF1!1.13!12.63!LEF1;;chr21:36421535..36421610,-!p2@RUNX1!1.12!43.22!RUNX1;;chr10:94449675..94449694,+!p2@HHEX!1.12!32.74!HHEX;;chrX:48644976..48644983,+!p2@GATA1!1.12!12.13!GATA1;;chr7:50344251..50344288,+!p3@IKZF1!1.11!11.97!IKZF1;;chr4:109088940..109089037,-!p4@LEF1!1.10!11.47!LEF1;;chr2:145277640..145277771,-!p1@ZEB2!1.08!147.76!ZEB2;;chr7:63505799..63505904,+!p1@ZNF727!1.08!11.14!ZNF727;;chr19:22817119..22817145,+!p1@ZNF492!1.07!17.95!ZNF492;;chr6:144385698..144385742,-!p2@PLAGL1!1.07!12.96!PLAGL1;;chr7:115670804..115670825,-!p1@TFEC!1.05!10.14!TFEC;;chr19:13213465..13213478,-!p7@LYL1!1.04!9.97!LYL1;;chr8:60031619..60031676,-!p1@TOX!1.03!21.28!TOX;;chr17:38020392..38020477,-!p1@IKZF3!1.03!9.64!IKZF3;;chr7:50343634..50343717,+!p2@IKZF1!1.02!9.47!IKZF1;;chr17:40440481..40440550,+!p1@STAT5A!1.01!68.31!STAT5A;;chr18:22932080..22932170,-!p1@ZNF521!1.00!39.39!ZNF521;;chrX:48645010..48645015,+!p3@GATA1!0.99!8.81!GATA1;;chr5:88178983..88179012,-!p1@MEF2C!0.97!65.82!MEF2C;;chr8:28748099..28748141,+!p2@HMBOX1!0.97!26.43!HMBOX1;;chr1:47697539..47697573,-!p3@TAL1!0.95!7.98!TAL1;;chr2:214013461..214013517,-!p6@IKZF2!0.95!7.81!IKZF2;;chr13:41593425..41593480,-!p1@ELF1!0.94!50.53!ELF1;;chr12:54691711..54691725,-!p7@NFE2!0.90!6.98!NFE2;;chr1:61548069..61548102,+!p3@NFIA!0.89!16.95!NFIA;;chr6:135513595..135513617,+!p4@MYB!0.89!6.81!MYB;;chr12:54689552..54689574,-!p6@NFE2!0.88!6.65!NFE2;;chr9:135854074..135854089,+!p2@GFI1B!0.88!6.65!GFI1B;;chr20:61051039..61051057,-!p1@GATA5!0.88!6.65!GATA5;;chr3:141747459..141747475,-!p1@TFDP2!0.87!56.01!TFDP2;;chr1:92951607..92951661,-!p1@GFI1!0.87!6.48!GFI1;;chr12:54694738..54694749,-!p5@NFE2!0.86!6.32!NFE2;;chr4:87857474..87857489,+!p7@AFF1!0.85!10.97!AFF1;;chr11:32457103..32457123,-!p3@WT1!0.85!6.15!WT1;;chr8:145669791..145669834,-!p1@TONSL!0.84!17.78!TONSL;;chr3:157823517..157823562,-!p1@SHOX2!0.83!6.15!SHOX2;;chr1:61548225..61548299,+!p1@NFIA!0.82!78.78!NFIA;;chr4:4291837..4291859,-!p2@LYAR!0.82!19.28!LYAR;;chr3:63953435..63953499,+!p1@ATXN7!0.82!5.65!ATXN7;;chr5:88179017..88179046,-!p2@MEF2C!0.81!23.60!MEF2C;;chr19:11959532..11959593,+!p1@ZNF439!0.81!22.60!ZNF439;;chr8:28748157..28748175,+!p3@HMBOX1!0.81!6.81!HMBOX1;;chr19:57183114..57183145,-!p1@ZNF835!0.81!6.15!ZNF835;;chr7:35293685..35293718,-!p1@TBX20!0.81!5.48!TBX20;;chr8:128748308..128748324,+!p2@MYC!0.80!158.57!MYC;;chr6:7107999..7108031,+!p2@RREB1!0.80!30.42!RREB1;;chr6:15246200..15246214,+!p2@JARID2!0.79!15.13!JARID2;;chr13:36871902..36872023,-!p1@CCDC169-SOHLH2,p1@CCDC169,p1@SOHLH2!0.78!11.63!SOHLH2;;chr14:75988771..75988826,+!p1@BATF!0.78!6.81!BATF;;chr11:47399920..47399931,-!p7@SPI1!0.78!4.99!SPI1;;chr6:144329384..144329405,-!p1@PLAGL1!0.76!60.67!PLAGL1;;chr11:130184311..130184362,-!p4@ZBTB44!0.76!8.98!ZBTB44;;chr15:96875657..96875760,+!p14@NR2F2!0.76!8.31!NR2F2;;chr12:54778471..54778528,-!p1@ZNF385A!0.76!4.82!ZNF385A;;chr4:87928413..87928433,+!p3@AFF1!0.75!31.75!AFF1;;chrX:131623044..131623089,-!p1@MBNL3!0.75!21.11!MBNL3;;chr15:67391010..67391046,+!p13@SMAD3!0.75!4.65!SMAD3;;chr4:109089290..109089320,-!p14@LEF1!0.75!4.65!LEF1;;chr11:62369108..62369183,-!p3@MTA2!0.73!62.99!MTA2;;chr16:68119324..68119364,+!p1@NFATC3!0.73!21.61!NFATC3;;chr4:87857433..87857472,+!p9@AFF1!0.73!8.31!AFF1;;chr4:87857491..87857519,+!p10@AFF1!0.73!6.32!AFF1;;chr12:54691726..54691738,-!p9@NFE2!0.73!4.32!NFE2;;chr19:11998584..11998649,+!p1@ZNF69!0.72!20.94!ZNF69;;chr6:20402102..20402152,+!p1@E2F3!0.72!19.11!E2F3;;chr19:12203100..12203132,+!p1@ZNF788!0.72!9.31!ZNF788;;chr6:126240463..126240489,+!p6@NCOA7!0.72!4.82!NCOA7;;chr16:88519669..88519726,+!p1@ZFPM1!0.71!42.38!ZFPM1;;chr3:128207349..128207386,-!p3@GATA2!0.71!4.16!GATA2;;chr3:141747950..141748004,-!p7@TFDP2!0.71!4.16!TFDP2;;chr19:45579725..45579743,-!p1@ZNF296!0.70!20.11!ZNF296;;chr8:65493017..65493035,+!p4@BHLHE22!0.70!3.99!BHLHE22;;chr19:13213662..13213686,-!p1@LYL1!0.69!6.15!LYL1;;chr19:21950332..21950356,-!p2@ZNF100!0.68!8.81!ZNF100;;chr8:60031809..60031835,-!p4@TOX!0.68!4.99!TOX;;chr2:60781201..60781258,-!p3@BCL11A!0.68!3.82!BCL11A;;chr17:40440446..40440464,+!p5@STAT5A!0.68!3.82!STAT5A;;chr11:32457075..32457095,-!p1@WT1!0.68!3.82!WT1;;chr21:30671690..30671762,+!p2@BACH1!0.67!14.13!BACH1;;chr11:130184470..130184533,-!p2@ZBTB44!0.67!11.14!ZBTB44;;chr6:15401104..15401166,+!p5@JARID2!0.67!3.66!JARID2;;chrY:2803415..2803468,+!p1@ZFY!0.67!3.66!ZFY;;chr4:109088130..109088163,-!p13@LEF1!0.67!3.66!LEF1;;chr8:128748470..128748487,+!p1@MYC!0.66!460.74!MYC;;chr6:134274354..134274371,+!p1@TBPL1!0.66!111.03!TBPL1;;chr20:42295713..42295738,+!p2@MYBL2!0.66!24.27!MYBL2;;chr16:68119440..68119480,+!p4@NFATC3!0.66!6.32!NFATC3;;chr17:40428359..40428462,-!p1@STAT5B!0.65!51.53!STAT5B;;chr3:69788576..69788648,+!p1@MITF!0.65!21.44!MITF;;chr19:20011744..20011770,+!p1@ZNF93!0.65!15.29!ZNF93;;chr6:144329500..144329526,-!p4@PLAGL1!0.65!8.98!PLAGL1;;chr8:60031682..60031710,-!p2@TOX!0.65!5.98!TOX;;chr8:65492915..65492932,+!p1@BHLHE22!0.65!3.49!BHLHE22;;chr19:13213496..13213501,-!p10@LYL1!0.65!3.49!LYL1;;chr11:47400062..47400077,-!p2@SPI1!0.65!3.49!SPI1;;chr1:47696918..47696935,-!p6@TAL1!0.65!3.49!TAL1;;chr21:36260980..36261011,-!p1@RUNX1!0.64!114.35!RUNX1;;chr1:47779762..47779827,-!p1@STIL,p1@TAL1!0.64!17.62!TAL1;;chr15:41913690..41913753,+!p2@MGA!0.64!8.98!MGA;;chr2:185463247..185463263,+!p1@ZNF804A!0.64!6.48!ZNF804A;;chr8:60031762..60031803,-!p3@TOX!0.64!5.15!TOX;;chr17:46622205..46622218,-!p3@HOXB2!0.64!3.99!HOXB2;;chr2:43453734..43453751,-!p1@ZFP36L2!0.63!413.87!ZFP36L2;;chr1:202777535..202777556,-!p1@KDM5B!0.63!129.48!KDM5B;;chr19:23433144..23433204,-!p1@ZNF724P!0.63!17.12!ZNF724P;;chr7:128577972..128578047,+!p1@IRF5!0.63!5.48!IRF5;;chr16:88519743..88519754,+!p2@ZFPM1!0.63!3.66!ZFPM1;;chr21:40177892..40177903,+!p2@ETS2!0.62!14.79!ETS2;;chr4:109089901..109089930,-!p3@LEF1!0.62!3.16!LEF1;;chr5:88180342..88180365,-!p10@MEF2C!0.62!3.16!MEF2C;;chr11:128563948..128564003,+!p1@FLI1!0.61!44.05!FLI1;;chr12:57504975..57505019,-!p2@STAT6!0.61!14.79!STAT6;;chr19:52956798..52956843,+!p1@ZNF578!0.61!6.81!ZNF578;;chr20:62462566..62462631,-!p1@ZBTB46!0.61!6.48!ZBTB46;;chr3:44626446..44626477,+!p1@ZNF660!0.61!6.15!ZNF660;;chr11:65686952..65686975,+!p5@DRAP1!0.60!19.78!DRAP1;;chr2:60780753..60780800,-!p1@BCL11A!0.60!17.45!BCL11A;;chr21:36262032..36262062,-!p5@RUNX1!0.60!8.98!RUNX1;;chr2:192015701..192015743,-!p1@STAT4!0.60!4.32!STAT4;;chr11:19262486..19262512,-!p4@E2F8!0.60!3.82!E2F8;;chr2:68592394..68592405,+!p2@PLEK!0.60!2.99!PLEK;;chr20:42295745..42295765,+!p1@MYBL2!0.59!58.17!MYBL2;;chr12:11802547..11802560,+!p5@ETV6!0.59!4.32!ETV6;;chr6:85473156..85473210,-!p2@TBX18!0.59!3.66!TBX18;;chr19:45579762..45579772,-!p2@ZNF296!0.59!3.32!ZNF296;;chr6:157099198..157099221,+!p3@ARID1B!0.58!10.80!ARID1B;;chr7:27135591..27135658,-!p1@HOXA1!0.58!5.98!HOXA1;;chr6:144329531..144329546,-!p5@PLAGL1!0.58!4.82!PLAGL1;;chrX:84499081..84499115,+!p2@ZNF711!0.58!4.49!ZNF711;;chr11:19263160..19263176,-!p1@E2F8!0.58!3.49!E2F8;;chr12:54778351..54778378,-!p6@ZNF385A!0.58!2.83!ZNF385A;;chr2:185463521..185463557,+!p3@ZNF804A!0.58!2.83!ZNF804A;;chr2:214014959..214015006,-!p4@IKZF2!0.58!2.83!IKZF2;;chr2:242556900..242556916,-!p6@THAP4!0.58!2.83!THAP4;;chr9:135854058..135854072,+!p3@GFI1B!0.58!2.83!GFI1B;;chr6:15246261..15246312,+!p1@JARID2!0.57!82.77!JARID2;;chr2:239148671..239148686,-!p1@HES6!0.57!11.97!HES6;;chr6:144289132..144289134,-!p3@PLAGL1!0.57!7.31!PLAGL1;;chr10:94449649..94449664,+!p3@HHEX!0.57!4.32!HHEX;;chr1:27022164..27022220,+!p2@ARID1A!0.56!23.93!ARID1A;;chr19:47538560..47538591,+!p2@NPAS1!0.56!2.66!NPAS1;;chr11:19262421..19262455,-!p3@E2F8!0.56!2.66!E2F8;;chr8:37963511..37963523,+!p4@ASH2L!0.56!2.66!ASH2L;;chrY:21906761..21906810,-!p2@KDM5D!0.56!2.66!KDM5D;;chr1:226595741..226595818,-!p1@PARP1!0.55!166.21!PARP1;;chr11:65687362..65687436,+!p3@DRAP1!0.55!14.29!DRAP1;;chr15:37390850..37390909,-!p3@MEIS2!0.55!5.65!MEIS2;;chr6:126240442..126240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|sample_dev_stage=
|ffid_belonging_in_development=CL:0000049,CL:0000134
|sample_tissue=blood
|sample_donor(cell lot)=
|sample_sex=male
|sample_age=20
|sample_ethnicity=unknown
|rna_rin=
|rna_od260/230=2.11
|rna_od260/280=2.14
|sample_cell_type=myeloid progenitor cell
|sample_cell_line=MEG-A2
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest)
|sample_experimental_condition=
|sample_disease=chronic myelogenous leukemia (CML)
|rna_sample_type=total RNA
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0
|rna_weight_ug=31.9842
|rna_concentration=0.71076
|sample_note=
|profile_hcage=CNhs11865,LSID830,release010,COMPLETED
|profile_cagescan=,,,
|profile_srnaseq=,,,
|profile_rnaseq=,,,
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000004,CL:0000012,CL:0000034,CL:0000037,CL:0000048,CL:0000049,CL:0000063,CL:0000134,CL:0000144,CL:0000219,CL:0000255,CL:0000548,CL:0000566,CL:0000723,CL:0000763,CL:0000837,CL:0000988,CL:0002032,CL:0002320,CL:0002371
|ancestors_in_anatomy_facet=UBERON:0000061,UBERON:0000465,UBERON:0000479,UBERON:0001062,UBERON:0002384
|ancestors_in_disease_facet=DOID:0050686,DOID:0060083,DOID:1240,DOID:14566,DOID:162,DOID:2531,DOID:4,DOID:8552,DOID:8692
|sample_description=
|fonse_cell_line=FF:0101035
|fonse_cell_line=FF:0101035
|fonse_cell_line_closure=FF:0101035
|fonse_cell_line_closure=FF:0101035
Line 66: Line 40:
|fonse_treatment=
|fonse_treatment=
|fonse_treatment_closure=
|fonse_treatment_closure=
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|rna_box=110
|rna_catalog_number=
|rna_concentration=0.71076
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0
|rna_lot_number=
|rna_od260/230=2.11
|rna_od260/280=2.14
|rna_position=F1
|rna_rin=
|rna_sample_type=total RNA
|rna_tube_id=110F1
|rna_weight_ug=31.9842
|sample_age=20
|sample_category=cell lines
|sample_cell_catalog=ifo50478
|sample_cell_line=MEG-A2
|sample_cell_lot=
|sample_cell_type=myeloid progenitor cell
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest)
|sample_company=JAPAN HEALTH SCIENCES FOUNDATION - Health Science Research Resources Bank
|sample_description=
|sample_dev_stage=
|sample_disease=chronic myelogenous leukemia (CML)
|sample_donor(cell lot)=
|sample_ethnicity=unknown
|sample_experimental_condition=
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;2.72953891144559e-284!GO:0043227;membrane-bound organelle;3.36780856579285e-240!GO:0043231;intracellular membrane-bound organelle;1.73767795876189e-239!GO:0043226;organelle;2.44965966419513e-229!GO:0043229;intracellular organelle;2.91587823439628e-228!GO:0005737;cytoplasm;2.01771939721719e-178!GO:0044422;organelle part;1.79401303042191e-157!GO:0044446;intracellular organelle part;1.77780359467136e-155!GO:0044237;cellular metabolic process;3.37274050855418e-128!GO:0044444;cytoplasmic part;3.45257715028467e-127!GO:0044238;primary metabolic process;4.91223940635436e-122!GO:0005634;nucleus;5.32312129081456e-117!GO:0043170;macromolecule metabolic process;2.31697973925447e-112!GO:0032991;macromolecular complex;1.05316502891168e-110!GO:0030529;ribonucleoprotein complex;2.38462887172331e-95!GO:0044428;nuclear part;4.75753059075216e-94!GO:0043233;organelle lumen;7.63446662729945e-92!GO:0031974;membrane-enclosed lumen;7.63446662729945e-92!GO:0003723;RNA binding;7.76218792685921e-85!GO:0005739;mitochondrion;2.02392745662285e-79!GO:0043283;biopolymer metabolic process;1.42312418894515e-69!GO:0010467;gene expression;3.07603821153524e-64!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;7.38041873976639e-63!GO:0005515;protein binding;2.2444778246167e-60!GO:0006396;RNA processing;3.80859530154427e-60!GO:0006412;translation;3.59813092486869e-58!GO:0031981;nuclear lumen;6.6450674942709e-58!GO:0043234;protein complex;1.87345311841662e-55!GO:0005840;ribosome;1.09335335351004e-54!GO:0044429;mitochondrial part;6.90011819455994e-54!GO:0019538;protein metabolic process;3.58612176403587e-53!GO:0009058;biosynthetic process;1.9105489755667e-51!GO:0044249;cellular biosynthetic process;1.31272717547672e-48!GO:0031967;organelle envelope;1.49382155248562e-48!GO:0031090;organelle membrane;2.10172524056873e-48!GO:0031975;envelope;3.93319283297412e-48!GO:0044267;cellular protein metabolic process;5.36617062009921e-48!GO:0016071;mRNA metabolic process;8.93019813153756e-48!GO:0003735;structural constituent of ribosome;1.41604479052728e-47!GO:0044260;cellular macromolecule metabolic process;3.22551001850813e-47!GO:0009059;macromolecule biosynthetic process;1.09388403798144e-46!GO:0003676;nucleic acid binding;2.60746873768887e-45!GO:0033036;macromolecule localization;5.33627467861073e-45!GO:0008380;RNA splicing;1.38804720323546e-42!GO:0015031;protein transport;7.47914527858732e-42!GO:0005829;cytosol;9.08981654444044e-42!GO:0006259;DNA metabolic process;2.0672192237606e-41!GO:0006397;mRNA processing;2.0672192237606e-41!GO:0016043;cellular component organization and biogenesis;2.32129338545992e-41!GO:0033279;ribosomal subunit;2.65112152443056e-41!GO:0008104;protein localization;2.13110189230085e-40!GO:0045184;establishment of protein localization;9.60246623389116e-40!GO:0065003;macromolecular complex assembly;3.66027676041748e-38!GO:0006996;organelle organization and biogenesis;2.21183797645432e-37!GO:0005654;nucleoplasm;4.04708719200336e-37!GO:0022613;ribonucleoprotein complex biogenesis and assembly;4.5448251156783e-37!GO:0046907;intracellular transport;4.1968339452521e-34!GO:0016070;RNA metabolic process;9.32083647014892e-34!GO:0005740;mitochondrial envelope;1.11637006844305e-32!GO:0043228;non-membrane-bound organelle;1.677478291703e-32!GO:0043232;intracellular non-membrane-bound organelle;1.677478291703e-32!GO:0022607;cellular component assembly;1.74091308221447e-32!GO:0019866;organelle inner membrane;8.80629641173219e-32!GO:0005681;spliceosome;2.86644401709729e-31!GO:0000166;nucleotide binding;4.65055913568816e-31!GO:0031966;mitochondrial membrane;1.58956722762885e-30!GO:0005830;cytosolic ribosome (sensu Eukaryota);7.02079342479345e-30!GO:0044445;cytosolic part;1.92388354294274e-29!GO:0007049;cell cycle;2.30768913139833e-29!GO:0044451;nucleoplasm part;3.62141363202313e-29!GO:0005743;mitochondrial inner membrane;4.41007274069823e-29!GO:0006886;intracellular protein transport;3.13250465328533e-28!GO:0051649;establishment of cellular localization;1.43609069230302e-26!GO:0031980;mitochondrial lumen;1.5923799743061e-26!GO:0005759;mitochondrial matrix;1.5923799743061e-26!GO:0051641;cellular localization;3.83333227734534e-26!GO:0006974;response to DNA damage stimulus;3.84752893037919e-23!GO:0016874;ligase activity;1.55703895451824e-22!GO:0022402;cell cycle process;2.09657323337374e-22!GO:0006119;oxidative phosphorylation;3.52078960374958e-22!GO:0032553;ribonucleotide binding;4.0364627805211e-22!GO:0032555;purine ribonucleotide binding;4.0364627805211e-22!GO:0015935;small ribosomal subunit;4.99739857017306e-22!GO:0000278;mitotic cell cycle;7.15857980213866e-22!GO:0005694;chromosome;9.94793778178818e-22!GO:0016462;pyrophosphatase activity;2.88710979971722e-21!GO:0005730;nucleolus;2.88710979971722e-21!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;3.56059186244798e-21!GO:0006281;DNA repair;3.93467118028738e-21!GO:0017076;purine nucleotide binding;4.56642343184235e-21!GO:0016817;hydrolase activity, acting on acid anhydrides;5.26801847450849e-21!GO:0044455;mitochondrial membrane part;8.30512916427805e-21!GO:0022618;protein-RNA complex assembly;8.57435407038938e-21!GO:0051276;chromosome organization and biogenesis;1.0425371917931e-20!GO:0005524;ATP binding;1.59257373057523e-20!GO:0015934;large ribosomal subunit;2.02378317210448e-20!GO:0032559;adenyl ribonucleotide binding;2.06935626708028e-20!GO:0017111;nucleoside-triphosphatase activity;2.52705928220045e-20!GO:0030554;adenyl nucleotide binding;4.32934052503418e-19!GO:0006512;ubiquitin cycle;4.80577165069887e-19!GO:0044427;chromosomal part;6.28665403444969e-19!GO:0012505;endomembrane system;7.62408340817851e-19!GO:0006457;protein folding;1.07719048619498e-18!GO:0044265;cellular macromolecule catabolic process;3.3876959078838e-18!GO:0022403;cell cycle phase;1.03110409844497e-17!GO:0008135;translation factor activity, nucleic acid binding;3.39456757690607e-17!GO:0005746;mitochondrial respiratory chain;4.86737653068116e-17!GO:0051186;cofactor metabolic process;6.91708891045518e-17!GO:0042254;ribosome biogenesis and assembly;8.15699429322113e-17!GO:0005635;nuclear envelope;1.06210954814739e-16!GO:0006325;establishment and/or maintenance of chromatin architecture;1.08729579739299e-16!GO:0048770;pigment granule;1.5004831089501e-16!GO:0042470;melanosome;1.5004831089501e-16!GO:0000087;M phase of mitotic cell cycle;2.88541784350224e-16!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);4.0329602139086e-16!GO:0016604;nuclear body;5.06359299246256e-16!GO:0006260;DNA replication;5.59219786821042e-16!GO:0008134;transcription factor binding;5.97723868761262e-16!GO:0007067;mitosis;6.20563864159016e-16!GO:0006323;DNA packaging;6.87068709492755e-16!GO:0006511;ubiquitin-dependent protein catabolic process;6.88471205246158e-16!GO:0044248;cellular catabolic process;7.02312459394089e-16!GO:0031965;nuclear membrane;7.12690457327592e-16!GO:0005761;mitochondrial ribosome;7.64722066140852e-16!GO:0000313;organellar ribosome;7.64722066140852e-16!GO:0043285;biopolymer catabolic process;7.7468270512505e-16!GO:0051603;proteolysis involved in cellular protein catabolic process;7.88204312204178e-16!GO:0019941;modification-dependent protein catabolic process;8.03114893485927e-16!GO:0043632;modification-dependent macromolecule catabolic process;8.03114893485927e-16!GO:0009719;response to endogenous stimulus;8.03114893485927e-16!GO:0016887;ATPase activity;1.18808206816347e-15!GO:0000398;nuclear mRNA splicing, via spliceosome;1.39053539503696e-15!GO:0000375;RNA splicing, via transesterification reactions;1.39053539503696e-15!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;1.39053539503696e-15!GO:0051301;cell division;1.46100871317204e-15!GO:0044453;nuclear membrane part;1.71064210729638e-15!GO:0043412;biopolymer modification;1.79974941744542e-15!GO:0050136;NADH dehydrogenase (quinone) activity;1.93031410349896e-15!GO:0003954;NADH dehydrogenase activity;1.93031410349896e-15!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.93031410349896e-15!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;2.04211896342255e-15!GO:0044257;cellular protein catabolic process;2.11303369692885e-15!GO:0042623;ATPase activity, coupled;5.34440268121495e-15!GO:0009057;macromolecule catabolic process;6.21568688837954e-15!GO:0000279;M phase;2.06255272294098e-14!GO:0000502;proteasome complex (sensu Eukaryota);2.10363692754367e-14!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);4.36738582506558e-14!GO:0006605;protein targeting;7.74554742512652e-14!GO:0006464;protein modification process;1.93579489350819e-13!GO:0003743;translation initiation factor activity;2.0234399730446e-13!GO:0042775;organelle ATP synthesis coupled electron transport;2.09982124510401e-13!GO:0042773;ATP synthesis coupled electron transport;2.09982124510401e-13!GO:0004386;helicase activity;2.23191982935362e-13!GO:0005643;nuclear pore;2.23387238965739e-13!GO:0030964;NADH dehydrogenase complex (quinone);2.35852517341111e-13!GO:0045271;respiratory chain complex I;2.35852517341111e-13!GO:0005747;mitochondrial respiratory chain complex I;2.35852517341111e-13!GO:0050657;nucleic acid transport;2.63566811282962e-13!GO:0051236;establishment of RNA localization;2.63566811282962e-13!GO:0050658;RNA transport;2.63566811282962e-13!GO:0006915;apoptosis;3.47346665162868e-13!GO:0051082;unfolded protein binding;3.63597614378509e-13!GO:0012501;programmed cell death;3.73149472242808e-13!GO:0006403;RNA localization;4.51766981280927e-13!GO:0006413;translational initiation;5.87699698519644e-13!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;8.34828701689851e-13!GO:0006399;tRNA metabolic process;9.63583911721205e-13!GO:0006732;coenzyme metabolic process;1.14201226185948e-12!GO:0016607;nuclear speck;2.1478586359868e-12!GO:0048193;Golgi vesicle transport;2.2093434297369e-12!GO:0008219;cell death;2.38711752696517e-12!GO:0016265;death;2.38711752696517e-12!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;3.03117702173479e-12!GO:0030163;protein catabolic process;3.16507883840429e-12!GO:0050794;regulation of cellular process;3.54701491010355e-12!GO:0065004;protein-DNA complex assembly;4.05146597371343e-12!GO:0016192;vesicle-mediated transport;6.19012284034671e-12!GO:0044432;endoplasmic reticulum part;1.04556291909399e-11!GO:0006364;rRNA processing;1.37751105592533e-11!GO:0043687;post-translational protein modification;1.39176163634474e-11!GO:0051188;cofactor biosynthetic process;1.44331692329119e-11!GO:0005783;endoplasmic reticulum;1.79994435294399e-11!GO:0008026;ATP-dependent helicase activity;2.25390309303618e-11!GO:0016072;rRNA metabolic process;2.58632488035193e-11!GO:0065002;intracellular protein transport across a membrane;2.7614350784097e-11!GO:0051028;mRNA transport;2.92788416704309e-11!GO:0051726;regulation of cell cycle;3.33461077661583e-11!GO:0016568;chromatin modification;3.36497919947745e-11!GO:0006913;nucleocytoplasmic transport;3.8926387956218e-11!GO:0000074;regulation of progression through cell cycle;3.94929130316565e-11!GO:0006446;regulation of translational initiation;4.19531971866323e-11!GO:0046930;pore complex;4.30503482966156e-11!GO:0000785;chromatin;4.62042470596628e-11!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;6.28871640249837e-11!GO:0051169;nuclear transport;7.70716422020519e-11!GO:0003712;transcription cofactor activity;7.87548746877013e-11!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;1.64937693313366e-10!GO:0004812;aminoacyl-tRNA ligase activity;1.64937693313366e-10!GO:0016875;ligase activity, forming carbon-oxygen bonds;1.64937693313366e-10!GO:0006333;chromatin assembly or disassembly;1.8961857942039e-10!GO:0006461;protein complex assembly;2.37362673770812e-10!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;2.52340244358013e-10!GO:0016740;transferase activity;2.98009658548302e-10!GO:0019222;regulation of metabolic process;4.17074723492246e-10!GO:0043038;amino acid activation;4.17334017552793e-10!GO:0006418;tRNA aminoacylation for protein translation;4.17334017552793e-10!GO:0043039;tRNA aminoacylation;4.17334017552793e-10!GO:0005794;Golgi apparatus;5.31961843326809e-10!GO:0008565;protein transporter activity;6.97401253233371e-10!GO:0006163;purine nucleotide metabolic process;6.97401253233371e-10!GO:0006164;purine nucleotide biosynthetic process;1.13536618596269e-09!GO:0009259;ribonucleotide metabolic process;1.19502365337273e-09!GO:0016779;nucleotidyltransferase activity;1.50749556574343e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;2.21090462786303e-09!GO:0006366;transcription from RNA polymerase II promoter;2.83452695330392e-09!GO:0008639;small protein conjugating enzyme activity;4.50074062590835e-09!GO:0009260;ribonucleotide biosynthetic process;5.01346047991952e-09!GO:0042175;nuclear envelope-endoplasmic reticulum network;5.56288939831309e-09!GO:0009150;purine ribonucleotide metabolic process;5.89936127508799e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;6.02960066957161e-09!GO:0009056;catabolic process;6.60752529649782e-09!GO:0050789;regulation of biological process;6.96680672154727e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;8.32816768392001e-09!GO:0009152;purine ribonucleotide biosynthetic process;9.65178497445021e-09!GO:0030532;small nuclear ribonucleoprotein complex;1.01752936329547e-08!GO:0004842;ubiquitin-protein ligase activity;1.04047463962648e-08!GO:0005789;endoplasmic reticulum membrane;1.05263933251653e-08!GO:0003697;single-stranded DNA binding;1.08288695682131e-08!GO:0009060;aerobic respiration;1.08288695682131e-08!GO:0017038;protein import;1.52847431201592e-08!GO:0016787;hydrolase activity;1.81634709580131e-08!GO:0015986;ATP synthesis coupled proton transport;3.10376670694408e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;3.10376670694408e-08!GO:0019787;small conjugating protein ligase activity;3.61553684650749e-08!GO:0043566;structure-specific DNA binding;4.22143461351563e-08!GO:0019829;cation-transporting ATPase activity;4.48662535150034e-08!GO:0009108;coenzyme biosynthetic process;6.17266526441217e-08!GO:0006261;DNA-dependent DNA replication;8.09438823122182e-08!GO:0031323;regulation of cellular metabolic process;8.4020321365439e-08!GO:0005819;spindle;9.09439769638581e-08!GO:0006334;nucleosome assembly;1.26456036656292e-07!GO:0015078;hydrogen ion transmembrane transporter activity;1.27238991239804e-07!GO:0006793;phosphorus metabolic process;1.30037019488568e-07!GO:0006796;phosphate metabolic process;1.30037019488568e-07!GO:0009142;nucleoside triphosphate biosynthetic process;1.43884389567537e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.43884389567537e-07!GO:0005793;ER-Golgi intermediate compartment;1.44033054829867e-07!GO:0000775;chromosome, pericentric region;1.48999457773352e-07!GO:0007005;mitochondrion organization and biogenesis;1.49047167760755e-07!GO:0051246;regulation of protein metabolic process;1.55405717041897e-07!GO:0009055;electron carrier activity;1.67365407978731e-07!GO:0042981;regulation of apoptosis;1.70786000135439e-07!GO:0016881;acid-amino acid ligase activity;1.72004210501657e-07!GO:0006350;transcription;1.94765491729555e-07!GO:0009199;ribonucleoside triphosphate metabolic process;1.99442114849328e-07!GO:0009141;nucleoside triphosphate metabolic process;2.16298874906305e-07!GO:0003713;transcription coactivator activity;2.28223362524671e-07!GO:0045333;cellular respiration;2.28223362524671e-07!GO:0031497;chromatin assembly;2.28223362524671e-07!GO:0043067;regulation of programmed cell death;2.31948623167657e-07!GO:0048475;coated membrane;2.39615731147702e-07!GO:0030117;membrane coat;2.39615731147702e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;2.414500658308e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;2.414500658308e-07!GO:0000245;spliceosome assembly;2.96209749650868e-07!GO:0006754;ATP biosynthetic process;3.0697209529906e-07!GO:0006753;nucleoside phosphate metabolic process;3.0697209529906e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;3.3265738587522e-07!GO:0009144;purine nucleoside triphosphate metabolic process;3.3265738587522e-07!GO:0051329;interphase of mitotic cell cycle;3.64544096788262e-07!GO:0015630;microtubule cytoskeleton;4.29420736320564e-07!GO:0016310;phosphorylation;4.43062414520198e-07!GO:0005768;endosome;4.98925009614163e-07!GO:0003899;DNA-directed RNA polymerase activity;5.0649857759679e-07!GO:0006099;tricarboxylic acid cycle;6.27320971607427e-07!GO:0046356;acetyl-CoA catabolic process;6.27320971607427e-07!GO:0046034;ATP metabolic process;6.44154582535622e-07!GO:0045259;proton-transporting ATP synthase complex;7.01441840546545e-07!GO:0031202;RNA splicing factor activity, transesterification mechanism;8.35959632445483e-07!GO:0051325;interphase;8.68628077398764e-07!GO:0006084;acetyl-CoA metabolic process;1.10185656239517e-06!GO:0032446;protein modification by small protein conjugation;1.24637713862269e-06!GO:0016469;proton-transporting two-sector ATPase complex;1.27508883876522e-06!GO:0005813;centrosome;1.60280241508145e-06!GO:0005667;transcription factor complex;1.61925077712479e-06!GO:0006888;ER to Golgi vesicle-mediated transport;2.21017462480888e-06!GO:0005815;microtubule organizing center;2.21696650456504e-06!GO:0016567;protein ubiquitination;2.23026007516156e-06!GO:0006082;organic acid metabolic process;2.3836975585772e-06!GO:0019752;carboxylic acid metabolic process;2.39751342024435e-06!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;2.5241965024298e-06!GO:0010468;regulation of gene expression;2.65376838695686e-06!GO:0016563;transcription activator activity;3.22186822890844e-06!GO:0005762;mitochondrial large ribosomal subunit;3.78289902753511e-06!GO:0000315;organellar large ribosomal subunit;3.78289902753511e-06!GO:0006752;group transfer coenzyme metabolic process;3.90869973720229e-06!GO:0005839;proteasome core complex (sensu Eukaryota);4.05460544564745e-06!GO:0030120;vesicle coat;4.07437587277915e-06!GO:0030662;coated vesicle membrane;4.07437587277915e-06!GO:0000151;ubiquitin ligase complex;5.10164118208524e-06!GO:0048523;negative regulation of cellular process;5.55727441741451e-06!GO:0008654;phospholipid biosynthetic process;5.85122926264563e-06!GO:0016772;transferase activity, transferring phosphorus-containing groups;6.1203649012657e-06!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;6.63500579523974e-06!GO:0008094;DNA-dependent ATPase activity;7.05327354235651e-06!GO:0003724;RNA helicase activity;7.84459106162826e-06!GO:0000075;cell cycle checkpoint;8.25733608503496e-06!GO:0005657;replication fork;8.5195491109676e-06!GO:0051168;nuclear export;8.73072942187476e-06!GO:0009109;coenzyme catabolic process;9.12243531053054e-06!GO:0044452;nucleolar part;9.26575413639235e-06!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;9.49001480339072e-06!GO:0043069;negative regulation of programmed cell death;9.58431558815493e-06!GO:0006302;double-strand break repair;9.6617926585713e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;1.00937902710397e-05!GO:0043066;negative regulation of apoptosis;1.13577555816405e-05!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.1407766061138e-05!GO:0032774;RNA biosynthetic process;1.26845159843827e-05!GO:0008610;lipid biosynthetic process;1.41325888018239e-05!GO:0006613;cotranslational protein targeting to membrane;1.46021370090424e-05!GO:0051170;nuclear import;1.61653060138924e-05!GO:0006401;RNA catabolic process;1.61801000389675e-05!GO:0065007;biological regulation;1.63207384056272e-05!GO:0004298;threonine endopeptidase activity;1.6547966847771e-05!GO:0016363;nuclear matrix;1.67584797943918e-05!GO:0006351;transcription, DNA-dependent;1.70370079154505e-05!GO:0008270;zinc ion binding;1.87580026372858e-05!GO:0003677;DNA binding;1.91067939631592e-05!GO:0051187;cofactor catabolic process;1.91374946195786e-05!GO:0009117;nucleotide metabolic process;2.83072177490798e-05!GO:0006606;protein import into nucleus;2.88847196193217e-05!GO:0003729;mRNA binding;2.93431635548578e-05!GO:0005770;late endosome;3.04451230752997e-05!GO:0006402;mRNA catabolic process;3.47243533344979e-05!GO:0006310;DNA recombination;3.50481447210837e-05!GO:0007249;I-kappaB kinase/NF-kappaB cascade;3.51793027964833e-05!GO:0006916;anti-apoptosis;3.63539210931018e-05!GO:0051427;hormone receptor binding;3.86121044825076e-05!GO:0006352;transcription initiation;3.90149016955817e-05!GO:0031988;membrane-bound vesicle;4.62948477185594e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;5.200147998142e-05!GO:0016853;isomerase activity;5.90085402905573e-05!GO:0007051;spindle organization and biogenesis;6.15724676356185e-05!GO:0043623;cellular protein complex assembly;6.15724676356185e-05!GO:0000314;organellar small ribosomal subunit;7.13379200363561e-05!GO:0005763;mitochondrial small ribosomal subunit;7.13379200363561e-05!GO:0031982;vesicle;7.32951828998534e-05!GO:0003690;double-stranded DNA binding;7.38851199414019e-05!GO:0048519;negative regulation of biological process;7.38851199414019e-05!GO:0035257;nuclear hormone receptor binding;7.4160298500139e-05!GO:0044431;Golgi apparatus part;7.92381624558446e-05!GO:0004527;exonuclease activity;8.51470503584176e-05!GO:0046914;transition metal ion binding;8.87915257426944e-05!GO:0016491;oxidoreductase activity;9.40173445711866e-05!GO:0043021;ribonucleoprotein binding;0.000100652188852645!GO:0046483;heterocycle metabolic process;0.000129331577831156!GO:0005773;vacuole;0.000136212134812945!GO:0016023;cytoplasmic membrane-bound vesicle;0.000144577297993407!GO:0019899;enzyme binding;0.000146596212264519!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.000151707412884272!GO:0045786;negative regulation of progression through cell cycle;0.000159019986936555!GO:0003678;DNA helicase activity;0.000165879947219858!GO:0016741;transferase activity, transferring one-carbon groups;0.000171261491051599!GO:0006779;porphyrin biosynthetic process;0.000171261491051599!GO:0033014;tetrapyrrole biosynthetic process;0.000171261491051599!GO:0031968;organelle outer membrane;0.000171789025181569!GO:0008168;methyltransferase activity;0.000177567410140127!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000186208266151326!GO:0030880;RNA polymerase complex;0.000192691937997975!GO:0006612;protein targeting to membrane;0.000198315863200089!GO:0005798;Golgi-associated vesicle;0.00020215562036648!GO:0000776;kinetochore;0.000205770665198989!GO:0043681;protein import into mitochondrion;0.00020900183048843!GO:0019867;outer membrane;0.000214948335836445!GO:0006839;mitochondrial transport;0.00021526033112969!GO:0008033;tRNA processing;0.000216575854861025!GO:0005741;mitochondrial outer membrane;0.00022636632231111!GO:0016859;cis-trans isomerase activity;0.000230905862577096!GO:0005525;GTP binding;0.000240381445744128!GO:0045449;regulation of transcription;0.00024388727394018!GO:0006383;transcription from RNA polymerase III promoter;0.000247502279807989!GO:0006338;chromatin remodeling;0.000259942736705873!GO:0044440;endosomal part;0.000259942736705873!GO:0010008;endosome membrane;0.000259942736705873!GO:0003684;damaged DNA binding;0.000261892586406325!GO:0003682;chromatin binding;0.000278856651958018!GO:0006091;generation of precursor metabolites and energy;0.000280048987899472!GO:0045045;secretory pathway;0.000292025294600693!GO:0031410;cytoplasmic vesicle;0.000297556301110783!GO:0005788;endoplasmic reticulum lumen;0.000310164050803202!GO:0006950;response to stress;0.000310164050803202!GO:0000323;lytic vacuole;0.000312649089960955!GO:0005764;lysosome;0.000312649089960955!GO:0019843;rRNA binding;0.000317608491546396!GO:0007059;chromosome segregation;0.000337317182847873!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000345339378157448!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000355678917889877!GO:0006405;RNA export from nucleus;0.00036100857176176!GO:0004518;nuclease activity;0.000362532493964038!GO:0005885;Arp2/3 protein complex;0.00036694042213051!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.00036694042213051!GO:0015399;primary active transmembrane transporter activity;0.00036694042213051!GO:0006520;amino acid metabolic process;0.000391406141339233!GO:0000059;protein import into nucleus, docking;0.000398315679361392!GO:0006626;protein targeting to mitochondrion;0.000398564100670001!GO:0006778;porphyrin metabolic process;0.000411308101062388!GO:0033013;tetrapyrrole metabolic process;0.000411308101062388!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00041978464282455!GO:0000428;DNA-directed RNA polymerase complex;0.00041978464282455!GO:0008186;RNA-dependent ATPase activity;0.00041978464282455!GO:0003924;GTPase activity;0.000447492202758977!GO:0006414;translational elongation;0.000462787815959696!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000481388857686137!GO:0022890;inorganic cation transmembrane transporter activity;0.000491886674927842!GO:0032508;DNA duplex unwinding;0.000497581489599212!GO:0032392;DNA geometric change;0.000497581489599212!GO:0006783;heme biosynthetic process;0.000508950354215404!GO:0044255;cellular lipid metabolic process;0.000511893142902095!GO:0016281;eukaryotic translation initiation factor 4F complex;0.000511893142902095!GO:0031072;heat shock protein binding;0.000511893142902095!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.000511893142902095!GO:0006650;glycerophospholipid metabolic process;0.000550960820934446!GO:0065009;regulation of a molecular function;0.000552376181166772!GO:0007243;protein kinase cascade;0.000554497409950439!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.000591039589263473!GO:0030118;clathrin coat;0.000592762727969095!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000607721623849821!GO:0000786;nucleosome;0.000617488018839112!GO:0007006;mitochondrial membrane organization and biogenesis;0.000667979351934509!GO:0046474;glycerophospholipid biosynthetic process;0.000670252243833148!GO:0045454;cell redox homeostasis;0.000756199905368846!GO:0048471;perinuclear region of cytoplasm;0.000758264719831292!GO:0007088;regulation of mitosis;0.000783407161291304!GO:0005769;early endosome;0.000825196352547941!GO:0006268;DNA unwinding during replication;0.000832145346228327!GO:0000049;tRNA binding;0.000833373538340834!GO:0005637;nuclear inner membrane;0.000877588488033075!GO:0015992;proton transport;0.000882875881419482!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000940899541771537!GO:0007093;mitotic cell cycle checkpoint;0.000946361582721!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000961515348370582!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000961515348370582!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000961515348370582!GO:0051052;regulation of DNA metabolic process;0.00097208658956831!GO:0006818;hydrogen transport;0.00104310715427519!GO:0051252;regulation of RNA metabolic process;0.00107712468684317!GO:0006417;regulation of translation;0.00111299150944329!GO:0000139;Golgi membrane;0.00114763539478318!GO:0046467;membrane lipid biosynthetic process;0.00114763539478318!GO:0009165;nucleotide biosynthetic process;0.00115178501442053!GO:0004004;ATP-dependent RNA helicase activity;0.00118710165678972!GO:0031324;negative regulation of cellular metabolic process;0.00119087396981996!GO:0051920;peroxiredoxin activity;0.00123334651762022!GO:0042168;heme metabolic process;0.00132344428093078!GO:0016251;general RNA polymerase II transcription factor activity;0.00143676357193943!GO:0008047;enzyme activator activity;0.00148242055400195!GO:0030521;androgen receptor signaling pathway;0.00148745344300403!GO:0000922;spindle pole;0.00149799353175059!GO:0016197;endosome transport;0.00150378195322542!GO:0005684;U2-dependent spliceosome;0.0015324467166543!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00155680598178689!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00155680598178689!GO:0000082;G1/S transition of mitotic cell cycle;0.00156909062336115!GO:0032561;guanyl ribonucleotide binding;0.00158600300448404!GO:0019001;guanyl nucleotide binding;0.00158600300448404!GO:0006633;fatty acid biosynthetic process;0.00167180598993019!GO:0003714;transcription corepressor activity;0.00167180598993019!GO:0008234;cysteine-type peptidase activity;0.00168247375244309!GO:0032940;secretion by cell;0.00170456591644604!GO:0030384;phosphoinositide metabolic process;0.00171339069422558!GO:0006355;regulation of transcription, DNA-dependent;0.00173778360268829!GO:0008632;apoptotic program;0.00177300502706653!GO:0043492;ATPase activity, coupled to movement of substances;0.00183343785464259!GO:0005048;signal sequence binding;0.00192941611741518!GO:0015631;tubulin binding;0.00194356595090756!GO:0048500;signal recognition particle;0.00197881002926675!GO:0047485;protein N-terminus binding;0.00207804582789489!GO:0000096;sulfur amino acid metabolic process;0.0023582420016767!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00235828225970668!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0023710357425428!GO:0007052;mitotic spindle organization and biogenesis;0.00242410086529118!GO:0030867;rough endoplasmic reticulum membrane;0.00251627122717493!GO:0046394;carboxylic acid biosynthetic process;0.00256059756246061!GO:0016053;organic acid biosynthetic process;0.00256059756246061!GO:0042393;histone binding;0.0026114541036869!GO:0006284;base-excision repair;0.00264765628946311!GO:0006643;membrane lipid metabolic process;0.00267528022335804!GO:0043488;regulation of mRNA stability;0.00281849079549328!GO:0043487;regulation of RNA stability;0.00281849079549328!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.0028267566282056!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00289244714756764!GO:0005669;transcription factor TFIID complex;0.00295103801047829!GO:0003711;transcription elongation regulator activity;0.00305239058908145!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00307526635389914!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00318682306268578!GO:0016564;transcription repressor activity;0.00332370762212486!GO:0009081;branched chain family amino acid metabolic process;0.00344907252037941!GO:0030658;transport vesicle membrane;0.0034705937385977!GO:0007264;small GTPase mediated signal transduction;0.00350335957875661!GO:0006979;response to oxidative stress;0.00355450866180377!GO:0006519;amino acid and derivative metabolic process;0.00356219995618085!GO:0006891;intra-Golgi vesicle-mediated transport;0.00357947264466786!GO:0015980;energy derivation by oxidation of organic compounds;0.00370742654731944!GO:0030218;erythrocyte differentiation;0.00383586026428619!GO:0016126;sterol biosynthetic process;0.00397140147415855!GO:0006595;polyamine metabolic process;0.0040755502370686!GO:0004576;oligosaccharyl transferase activity;0.00409791635320938!GO:0046489;phosphoinositide biosynthetic process;0.00428842417557719!GO:0032984;macromolecular complex disassembly;0.00441803249919078!GO:0006367;transcription initiation from RNA polymerase II promoter;0.00450398496310195!GO:0030119;AP-type membrane coat adaptor complex;0.00453440472335386!GO:0008276;protein methyltransferase activity;0.00453440472335386!GO:0050790;regulation of catalytic activity;0.00454850702690938!GO:0031252;leading edge;0.00461355134117281!GO:0008312;7S RNA binding;0.00463220229235323!GO:0009892;negative regulation of metabolic process;0.00470672834348584!GO:0006730;one-carbon compound metabolic process;0.00472397141444289!GO:0051287;NAD binding;0.00476016036541747!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00479498495625412!GO:0016584;nucleosome positioning;0.00486121876418499!GO:0042802;identical protein binding;0.00489729104252276!GO:0005791;rough endoplasmic reticulum;0.00495687984754995!GO:0016481;negative regulation of transcription;0.00517278397281753!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00517697288918701!GO:0045047;protein targeting to ER;0.00517697288918701!GO:0006270;DNA replication initiation;0.00522258294549401!GO:0031124;mRNA 3'-end processing;0.00528312174710794!GO:0032259;methylation;0.00536039145530854!GO:0015036;disulfide oxidoreductase activity;0.00539763659648456!GO:0006289;nucleotide-excision repair;0.00546470883963101!GO:0018193;peptidyl-amino acid modification;0.00555757303611738!GO:0043414;biopolymer methylation;0.00561128700494071!GO:0005876;spindle microtubule;0.00575588455959994!GO:0051087;chaperone binding;0.00591006673184141!GO:0008250;oligosaccharyl transferase complex;0.0059126565588368!GO:0006144;purine base metabolic process;0.0059751634388455!GO:0006644;phospholipid metabolic process;0.00597613041120185!GO:0043241;protein complex disassembly;0.00609458460569272!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00632074299680057!GO:0016746;transferase activity, transferring acyl groups;0.00632518812069464!GO:0016747;transferase activity, transferring groups other than amino-acyl groups;0.00638122122769337!GO:0030131;clathrin adaptor complex;0.00639951032347341!GO:0030518;steroid hormone receptor signaling pathway;0.00641961403475242!GO:0031326;regulation of cellular biosynthetic process;0.00672786741319903!GO:0046456;icosanoid biosynthetic process;0.00692128473380879!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.00692128473380879!GO:0006695;cholesterol biosynthetic process;0.00706544543734589!GO:0008415;acyltransferase activity;0.007211959162325!GO:0000178;exosome (RNase complex);0.00740964682672313!GO:0019372;lipoxygenase pathway;0.00796265450476831!GO:0008139;nuclear localization sequence binding;0.00810606256603628!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.00811856332877032!GO:0035258;steroid hormone receptor binding;0.00822481091025361!GO:0016408;C-acyltransferase activity;0.00833330813379261!GO:0048487;beta-tubulin binding;0.00839162013345345!GO:0051789;response to protein stimulus;0.00839162013345345!GO:0006986;response to unfolded protein;0.00839162013345345!GO:0006611;protein export from nucleus;0.00867786786770733!GO:0016272;prefoldin complex;0.00873514720498487!GO:0006631;fatty acid metabolic process;0.00879587512511169!GO:0009112;nucleobase metabolic process;0.00881019421640112!GO:0008408;3'-5' exonuclease activity;0.0088701275631538!GO:0030660;Golgi-associated vesicle membrane;0.00895155142315686!GO:0032200;telomere organization and biogenesis;0.00895689733943582!GO:0000723;telomere maintenance;0.00895689733943582!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00929917198852051!GO:0003746;translation elongation factor activity;0.00941910553138528!GO:0043596;nuclear replication fork;0.00951578041817843!GO:0005096;GTPase activator activity;0.0095229908814547!GO:0030134;ER to Golgi transport vesicle;0.00952946300263152!GO:0000725;recombinational repair;0.00957633659805734!GO:0000724;double-strand break repair via homologous recombination;0.00957633659805734!GO:0030663;COPI coated vesicle membrane;0.00963762184923635!GO:0030126;COPI vesicle coat;0.00963762184923635!GO:0043624;cellular protein complex disassembly;0.00980005787151033!GO:0022415;viral reproductive process;0.00981341370610557!GO:0030176;integral to endoplasmic reticulum membrane;0.00981716036116535!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00981716036116535!GO:0015002;heme-copper terminal oxidase activity;0.00981716036116535!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00981716036116535!GO:0004129;cytochrome-c oxidase activity;0.00981716036116535!GO:0051540;metal cluster binding;0.00995782748485087!GO:0051536;iron-sulfur cluster binding;0.00995782748485087!GO:0043284;biopolymer biosynthetic process;0.00998913179783614!GO:0022411;cellular component disassembly;0.0102239088257338!GO:0004674;protein serine/threonine kinase activity;0.0113808831026513!GO:0043022;ribosome binding;0.0114703784460279!GO:0005758;mitochondrial intermembrane space;0.0117120292076964!GO:0006807;nitrogen compound metabolic process;0.0119940692252762!GO:0005832;chaperonin-containing T-complex;0.0120930420575439!GO:0006376;mRNA splice site selection;0.0122007577298123!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0122007577298123!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0122007577298123!GO:0009967;positive regulation of signal transduction;0.0122007577298123!GO:0033116;ER-Golgi intermediate compartment membrane;0.0129634499910849!GO:0019079;viral genome replication;0.0135669648644508!GO:0000118;histone deacetylase complex;0.0135669648644508!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0137548662394556!GO:0006892;post-Golgi vesicle-mediated transport;0.0139181539940649!GO:0030127;COPII vesicle coat;0.0140372858840943!GO:0012507;ER to Golgi transport vesicle membrane;0.0140372858840943!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0142786379282927!GO:0031570;DNA integrity checkpoint;0.0142941306401078!GO:0007021;tubulin folding;0.0143254827205422!GO:0005874;microtubule;0.0143561300606493!GO:0042158;lipoprotein biosynthetic process;0.0143686674372391!GO:0009308;amine metabolic process;0.0144379097413399!GO:0030137;COPI-coated vesicle;0.0148377124676072!GO:0006406;mRNA export from nucleus;0.0149627512642829!GO:0016407;acetyltransferase activity;0.0150997072070695!GO:0044438;microbody part;0.0151015253065287!GO:0044439;peroxisomal part;0.0151015253065287!GO:0018196;peptidyl-asparagine modification;0.015523306270593!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.015523306270593!GO:0031123;RNA 3'-end processing;0.0156437656996358!GO:0009889;regulation of biosynthetic process;0.0157091061135227!GO:0004177;aminopeptidase activity;0.0159410339599533!GO:0045947;negative regulation of translational initiation;0.0160087681606281!GO:0004003;ATP-dependent DNA helicase activity;0.0160087681606281!GO:0007050;cell cycle arrest;0.0160467085415908!GO:0050662;coenzyme binding;0.0162702720443118!GO:0006672;ceramide metabolic process;0.0165123999239458!GO:0006378;mRNA polyadenylation;0.0167130027168574!GO:0000792;heterochromatin;0.0167890132605259!GO:0000339;RNA cap binding;0.0169536844126939!GO:0008637;apoptotic mitochondrial changes;0.0170022347527625!GO:0043189;H4/H2A histone acetyltransferase complex;0.0174614956089229!GO:0032039;integrator complex;0.0175740605523838!GO:0048037;cofactor binding;0.0176862546584786!GO:0009083;branched chain family amino acid catabolic process;0.0177911116258149!GO:0000819;sister chromatid segregation;0.0178634712984709!GO:0006629;lipid metabolic process;0.0179618621019196!GO:0016790;thiolester hydrolase activity;0.0183964219610005!GO:0030695;GTPase regulator activity;0.0186221962967875!GO:0044262;cellular carbohydrate metabolic process;0.0186221962967875!GO:0006607;NLS-bearing substrate import into nucleus;0.0186221962967875!GO:0000287;magnesium ion binding;0.0187367463824062!GO:0005774;vacuolar membrane;0.0188635666252039!GO:0046966;thyroid hormone receptor binding;0.0192912652755764!GO:0030522;intracellular receptor-mediated signaling pathway;0.0195391645257629!GO:0007040;lysosome organization and biogenesis;0.0198744669924333!GO:0030508;thiol-disulfide exchange intermediate activity;0.0199029442439509!GO:0009451;RNA modification;0.0200523428522395!GO:0035267;NuA4 histone acetyltransferase complex;0.0202664330035174!GO:0046519;sphingoid metabolic process;0.0209077340375596!GO:0016585;chromatin remodeling complex;0.0209316242723888!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0214856057637348!GO:0031903;microbody membrane;0.0214856057637348!GO:0005778;peroxisomal membrane;0.0214856057637348!GO:0004532;exoribonuclease activity;0.021503568859103!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.021503568859103!GO:0006497;protein amino acid lipidation;0.0216491947361483!GO:0003725;double-stranded RNA binding;0.0217509046321669!GO:0006275;regulation of DNA replication;0.0218580828769476!GO:0030132;clathrin coat of coated pit;0.0221909896106052!GO:0031902;late endosome membrane;0.0222684885056565!GO:0040029;regulation of gene expression, epigenetic;0.0223238190577953!GO:0051539;4 iron, 4 sulfur cluster binding;0.0224071290631943!GO:0000726;non-recombinational repair;0.022684182582165!GO:0000070;mitotic sister chromatid segregation;0.0226860581878318!GO:0009066;aspartate family amino acid metabolic process;0.0227189843513536!GO:0045815;positive regulation of gene expression, epigenetic;0.0229565401933029!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0231353098592705!GO:0007010;cytoskeleton organization and biogenesis;0.0233047406584202!GO:0003857;3-hydroxyacyl-CoA dehydrogenase activity;0.0233047406584202!GO:0031625;ubiquitin protein ligase binding;0.0239112177825654!GO:0031970;organelle envelope lumen;0.0239963746746406!GO:0006220;pyrimidine nucleotide metabolic process;0.0240269778542107!GO:0019783;small conjugating protein-specific protease activity;0.0244455046833884!GO:0022406;membrane docking;0.0244455046833884!GO:0048278;vesicle docking;0.0244455046833884!GO:0008097;5S rRNA binding;0.0246269219816035!GO:0009067;aspartate family amino acid biosynthetic process;0.0247339699716264!GO:0000097;sulfur amino acid biosynthetic process;0.0249293285002028!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0251708863827321!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0251887619568666!GO:0051053;negative regulation of DNA metabolic process;0.0253233477902896!GO:0007265;Ras protein signal transduction;0.0253233477902896!GO:0000123;histone acetyltransferase complex;0.0253233477902896!GO:0030133;transport vesicle;0.0255084615672667!GO:0001726;ruffle;0.0256808051609433!GO:0007017;microtubule-based process;0.0259682943211413!GO:0032787;monocarboxylic acid metabolic process;0.0259751433411221!GO:0008287;protein serine/threonine phosphatase complex;0.0261977427155825!GO:0007242;intracellular signaling cascade;0.0262031923871788!GO:0016605;PML body;0.0265001421452117!GO:0008144;drug binding;0.0265031462298194!GO:0043601;nuclear replisome;0.0267685162214124!GO:0030894;replisome;0.0267685162214124!GO:0006506;GPI anchor biosynthetic process;0.0269937131767415!GO:0008017;microtubule binding;0.0270622556416635!GO:0004843;ubiquitin-specific protease activity;0.0270622556416635!GO:0000228;nuclear chromosome;0.0271027480071816!GO:0009303;rRNA transcription;0.0272947323809325!GO:0000910;cytokinesis;0.0276046779886293!GO:0050178;phenylpyruvate tautomerase activity;0.0278391291965953!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0285005232135493!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0289441957229029!GO:0030496;midbody;0.0294379191267758!GO:0006100;tricarboxylic acid cycle intermediate metabolic process;0.0305643185589877!GO:0043065;positive regulation of apoptosis;0.0309540400908846!GO:0006917;induction of apoptosis;0.0310940915711739!GO:0008213;protein amino acid alkylation;0.0310940915711739!GO:0006479;protein amino acid methylation;0.0310940915711739!GO:0006509;membrane protein ectodomain proteolysis;0.0325678224260657!GO:0033619;membrane protein proteolysis;0.0325678224260657!GO:0016835;carbon-oxygen lyase activity;0.0326777329036172!GO:0006596;polyamine biosynthetic process;0.0327292580165431!GO:0009124;nucleoside monophosphate biosynthetic process;0.0327292580165431!GO:0009123;nucleoside monophosphate metabolic process;0.0327292580165431!GO:0005869;dynactin complex;0.0327581989243273!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0327581989243273!GO:0006555;methionine metabolic process;0.0330207348429772!GO:0044450;microtubule organizing center part;0.0330227168695337!GO:0012506;vesicle membrane;0.0334153172151923!GO:0004300;enoyl-CoA hydratase activity;0.0334762616575584!GO:0030036;actin cytoskeleton organization and biogenesis;0.0334995273931411!GO:0006118;electron transport;0.0334995273931411!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0337449178391335!GO:0005765;lysosomal membrane;0.0337453490707526!GO:0006733;oxidoreduction coenzyme metabolic process;0.0337894865040054!GO:0042809;vitamin D receptor binding;0.0339436724921478!GO:0046128;purine ribonucleoside metabolic process;0.0339576355889153!GO:0042278;purine nucleoside metabolic process;0.0339576355889153!GO:0043068;positive regulation of programmed cell death;0.0340229692166101!GO:0031577;spindle checkpoint;0.0340972619115977!GO:0050681;androgen receptor binding;0.0345283604658863!GO:0031371;ubiquitin conjugating enzyme complex;0.0351414385252977!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.0351414385252977!GO:0006904;vesicle docking during exocytosis;0.0351820044480972!GO:0004428;inositol or phosphatidylinositol kinase activity;0.0351820044480972!GO:0005095;GTPase inhibitor activity;0.0352451111189871!GO:0012502;induction of programmed cell death;0.0352585267782757!GO:0000077;DNA damage checkpoint;0.035663392652416!GO:0004239;methionyl aminopeptidase activity;0.0359020246348678!GO:0048146;positive regulation of fibroblast proliferation;0.0359020246348678!GO:0006740;NADPH regeneration;0.0359731119614752!GO:0006098;pentose-phosphate shunt;0.0359731119614752!GO:0030125;clathrin vesicle coat;0.0361989945139995!GO:0030665;clathrin coated vesicle membrane;0.0361989945139995!GO:0007033;vacuole organization and biogenesis;0.0363182346598982!GO:0005652;nuclear lamina;0.0364217715310699!GO:0048144;fibroblast proliferation;0.0364217715310699!GO:0048145;regulation of fibroblast proliferation;0.0364217715310699!GO:0032287;myelin maintenance in the peripheral nervous system;0.0364217715310699!GO:0032838;cell projection cytoplasm;0.0364217715310699!GO:0033081;regulation of T cell differentiation in the thymus;0.0364217715310699!GO:0043217;myelin maintenance;0.0364217715310699!GO:0060087;relaxation of vascular smooth muscle;0.0364217715310699!GO:0032839;dendrite cytoplasm;0.0364217715310699!GO:0005784;translocon complex;0.0364809580479865!GO:0044437;vacuolar part;0.036792295671386!GO:0003887;DNA-directed DNA polymerase activity;0.0372058870812418!GO:0000152;nuclear ubiquitin ligase complex;0.0374086973134313!GO:0006360;transcription from RNA polymerase I promoter;0.0386751717835987!GO:0051338;regulation of transferase activity;0.0387568019270986!GO:0006505;GPI anchor metabolic process;0.0389064786860725!GO:0048522;positive regulation of cellular process;0.0389064786860725!GO:0003702;RNA polymerase II transcription factor activity;0.0391039507221237!GO:0030911;TPR domain binding;0.0393718494079327!GO:0004221;ubiquitin thiolesterase activity;0.0402525822492239!GO:0051235;maintenance of localization;0.0402817326403591!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0407601069914035!GO:0001784;phosphotyrosine binding;0.041632729270472!GO:0008180;signalosome;0.0416425590687305!GO:0000303;response to superoxide;0.0416425590687305!GO:0005521;lamin binding;0.0429613153332381!GO:0008652;amino acid biosynthetic process;0.0429613153332381!GO:0006007;glucose catabolic process;0.0430617189765999!GO:0016180;snRNA processing;0.0430983061441581!GO:0016073;snRNA metabolic process;0.0430983061441581!GO:0046588;negative regulation of calcium-dependent cell-cell adhesion;0.0435816193630272!GO:0046586;regulation of calcium-dependent cell-cell adhesion;0.0435816193630272!GO:0000209;protein polyubiquitination;0.0436326760883254!GO:0019206;nucleoside kinase activity;0.0441954690281555!GO:0006516;glycoprotein catabolic process;0.0444464166593689!GO:0007259;JAK-STAT cascade;0.0444464166593689!GO:0003756;protein disulfide isomerase activity;0.0445625516695435!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0445625516695435!GO:0006458;'de novo' protein folding;0.0446043851910519!GO:0051084;'de novo' posttranslational protein folding;0.0446043851910519!GO:0019377;glycolipid catabolic process;0.0446372405761536!GO:0017134;fibroblast growth factor binding;0.0447310554958498!GO:0016125;sterol metabolic process;0.0451057596008646!GO:0006301;postreplication repair;0.0452421572170915!GO:0042054;histone methyltransferase activity;0.0455826840144227!GO:0004523;ribonuclease H activity;0.0456235000749359!GO:0001516;prostaglandin biosynthetic process;0.0456865303454886!GO:0046457;prostanoid biosynthetic process;0.0456865303454886!GO:0030659;cytoplasmic vesicle membrane;0.0456865303454886!GO:0043549;regulation of kinase activity;0.0464775139652341!GO:0000781;chromosome, telomeric region;0.0466243651902451!GO:0005083;small GTPase regulator activity;0.0471394924383533!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0471488466546985!GO:0045039;protein import into mitochondrial inner membrane;0.0471488466546985!GO:0030041;actin filament polymerization;0.0490900671742249!GO:0060090;molecular adaptor activity;0.0495399375358433!GO:0046983;protein dimerization activity;0.0497627078257935
|sample_id=10766
|sample_note=
|sample_sex=male
|sample_species=Human (Homo sapiens)
|sample_strain=
|sample_tissue=blood
|top_motifs=GATA6:4.17008204007;RXR{A,B,G}_{NR1H2,PPAR}dimers:2.11985678087;MYB:1.8229187037;STAT5{A,B}:1.3485278103;ALX1:1.23365072813;IKZF2:1.1833228366;E2F1..5:1.1404376186;NR5A1,2:1.09104721728;BREu{core}:1.08418574388;ELF1,2,4:1.00925362292;NR6A1:1.00417466035;PAX6:0.965771252341;CRX:0.950687652493;bHLH_family:0.901762542753;PITX1..3:0.893101520166;YY1:0.890751223367;HOXA9_MEIS1:0.83146512954;PPARG:0.825172925548;POU3F1..4:0.81591769758;RORA:0.799328233738;ZNF143:0.778639436352;ZNF148:0.746208288411;EN1,2:0.740655917451;FOX{I1,J2}:0.739629718269;ELK1,4_GABP{A,B1}:0.735761971361;STAT1,3:0.733781937881;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.713435361619;CUX2:0.657750030999;POU2F1..3:0.654127298104;TLX2:0.642480551395;SPIB:0.639925784554;PAX8:0.599874306156;ZBTB16:0.596779010562;TOPORS:0.569358070754;PBX1:0.551987996454;SPI1:0.531111245927;RUNX1..3:0.464159473392;OCT4_SOX2{dimer}:0.420091969446;ETS1,2:0.4022903416;RBPJ:0.391642665344;PRRX1,2:0.371766385087;POU1F1:0.37039609928;NFY{A,B,C}:0.360961355022;NANOG{mouse}:0.358382841743;HES1:0.352842432834;HAND1,2:0.347030275771;SOX{8,9,10}:0.340002609232;HOX{A6,A7,B6,B7}:0.329783663568;FOXP1:0.295420471598;POU6F1:0.259346112191;TFDP1:0.232455966168;ONECUT1,2:0.22772545984;EVI1:0.226181447259;DMAP1_NCOR{1,2}_SMARC:0.215036304484;AR:0.205314575373;PAX4:0.188755375865;NKX2-3_NKX2-5:0.124551303494;NRF1:0.112993994541;HBP1_HMGB_SSRP1_UBTF:0.108790339798;FOXP3:0.0978834142508;NKX2-1,4:0.0808062399783;NANOG:0.0687734739105;PAX3,7:0.0662871089819;SMAD1..7,9:0.0660631330437;TEF:0.0528653115693;ADNP_IRX_SIX_ZHX:0.0129342631123;HNF4A_NR2F1,2:-0.0158433775217;GCM1,2:-0.015903064967;HOX{A5,B5}:-0.0282114708134;FOXN1:-0.0416884716618;T:-0.0565625622892;NKX3-1:-0.0744377138446;AIRE:-0.0758475051455;ZFP161:-0.085724248341;SOX17:-0.0935918374209;SNAI1..3:-0.0973873094046;REST:-0.104307817642;NKX2-2,8:-0.115206731583;AHR_ARNT_ARNT2:-0.122736552986;NHLH1,2:-0.130942090443;MTF1:-0.135615197408;ARID5B:-0.169820906053;CDX1,2,4:-0.177802093314;POU5F1:-0.180066676891;NFKB1_REL_RELA:-0.186413328532;FOXQ1:-0.204231007463;PAX2:-0.205454792895;NFIX:-0.207905991706;RXR{A,B,G}:-0.219495244138;GZF1:-0.239170469863;LHX3,4:-0.246863084892;BPTF:-0.248524044166;MYOD1:-0.252345833791;ZEB1:-0.263817019503;HNF1A:-0.271616090151;TGIF1:-0.290244273285;ATF5_CREB3:-0.295353606129;XBP1:-0.298356667212;RXRA_VDR{dimer}:-0.302067776835;FOXM1:-0.310132540408;ZNF423:-0.317482966966;FOX{F1,F2,J1}:-0.318337424439;NFE2:-0.326260354293;NKX6-1,2:-0.327455176944;DBP:-0.332808310058;KLF4:-0.336795561653;ZNF384:-0.355158142999;SREBF1,2:-0.376041298048;HIF1A:-0.415300799414;NR1H4:-0.42343840308;VSX1,2:-0.441926067205;TFAP4:-0.450362456071;RFX2..5_RFXANK_RFXAP:-0.456441592357;HSF1,2:-0.45678667255;TFAP2{A,C}:-0.470876930399;CREB1:-0.475812134975;HOX{A4,D4}:-0.495341119867;FOXD3:-0.507589551409;NFIL3:-0.507899477935;IRF1,2:-0.507901719326;SOX5:-0.514852161168;STAT2,4,6:-0.533487534411;ZBTB6:-0.565673517939;PDX1:-0.570848202687;BACH2:-0.572843184925;TFAP2B:-0.580989844182;EGR1..3:-0.58396181601;NFE2L1:-0.618460815642;FOS_FOS{B,L1}_JUN{B,D}:-0.619888877399;MED-1{core}:-0.630764014512;MYBL2:-0.644423150302;MEF2{A,B,C,D}:-0.651759458001;ATF4:-0.657344269118;FOXA2:-0.662185042001;ESR1:-0.669375225616;MYFfamily:-0.671418825629;MTE{core}:-0.685203081295;UFEwm:-0.685331875697;IRF7:-0.690108087302;GTF2I:-0.697175159655;CDC5L:-0.6983559116;SRF:-0.710974336342;HIC1:-0.723207187603;GFI1:-0.729478386922;NKX3-2:-0.73238514344;LEF1_TCF7_TCF7L1,2:-0.74154383171;TBX4,5:-0.766875889781;EBF1:-0.76713577769;HLF:-0.781457753325;NFE2L2:-0.806907397277;XCPE1{core}:-0.812020817978;CEBPA,B_DDIT3:-0.814769726589;FOSL2:-0.825951912995;HMGA1,2:-0.826435039764;GLI1..3:-0.831632090337;ESRRA:-0.841217237677;RREB1:-0.844191963421;RFX1:-0.856098007956;HMX1:-0.86217214087;IKZF1:-0.87132436389;PAX1,9:-0.874832039592;MZF1:-0.895483548983;EP300:-0.900581541622;FOXO1,3,4:-0.916407580159;FOX{D1,D2}:-0.938278065473;ZNF238:-0.938500782657;GTF2A1,2:-0.938747252679;LMO2:-0.948288473254;PAX5:-0.95742837798;PATZ1:-0.963507220345;NFATC1..3:-0.968313341115;TBP:-0.970656639069;GATA4:-0.982267465051;ATF2:-1.02183051599;TP53:-1.02184345469;TLX1..3_NFIC{dimer}:-1.07771658239;SOX2:-1.09356756968;ATF6:-1.10776394353;TEAD1:-1.12277580345;ZIC1..3:-1.12868566854;PRDM1:-1.14709999165;GFI1B:-1.17131141218;FOXL1:-1.17319088905;SP1:-1.2230279638;TAL1_TCF{3,4,12}:-1.23673648197;SPZ1:-1.25087629097;MAZ:-1.2794761358;ALX4:-1.28019059225;MAFB:-1.36626832486;NR3C1:-1.37562528425;TFCP2:-1.59034965965;JUN:-1.67375157407
|xref=
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10766-110F1;search_select_hide=table117:FF:10766-110F1
}}
}}

Latest revision as of 15:03, 3 June 2020

Name:chronic myelogenous leukemia (CML) cell line:MEG-A2
Species:Human (Homo sapiens)
Library ID:CNhs11865
Sample type:cell lines
Genomic View: UCSC
RefEX:Specific genes
CAGEd-oPOSSUM:link
ZENBU report :link
Additional information
Sample information
strainNA
tissueblood
dev stageNA
sexmale
age20
cell typemyeloid progenitor cell
cell lineMEG-A2
companyJAPAN HEALTH SCIENCES FOUNDATION - Health Science Research Resources Bank
collaborationFANTOM5 OSC CORE (contact: Al Forrest)
External link for information[{{{sample_info_link}}} {{{sample_info_link}}}]
RNA information
lot numberNA
catalog numberNA
sample typetotal RNA
extraction protocol (Details)OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0

CAGE Accession numbers
MethodSample accession id
CAGE  SAMD00004724
Library accession numbers

Library idMethodExp. accession idRun accession id
CNhs11865 CAGE DRX007854 DRR008726
Accession ID Hg19

Library idBAMCTSS
CNhs11865 DRZ000151 DRZ001536
Accession ID Hg38

Library idBAMCTSS
CNhs11865 DRZ011501 DRZ012886
Download raw sequence, BAM & CTSS
Hg19
FastaBAMCTSS
downloaddownloaddonwload
Hg38
BAMCTSS
downloaddonwload


Relative expression to median (log10)


Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.



Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data

Coexpression clusterscore
C0-CD14-Eosinophils-Neutrophils-Basophils-CD34-immature-Peripheral0
C1-testis-epididymis-embryonic-medulla-pituitary-trachea-caudate0
C10-occipital-temporal-parietal-brain-duodenum-Neurons-Neural0
C100-rhabdomyosarcoma-gastric-pineal-Wilms-cervical-mesodermal-endometrial0
C101-small-cerebellum-maxillary-colon-parietal-epididymis-merkel0
C102-neuroblastoma-testicular-pituitary-carcinosarcoma-rectum-acantholytic-iPS0
C103-CD4-CD8-Natural-Peripheral-Whole-Neutrophils-Basophils0
C104-Mast-Basophils-immature-CD14-CD34-eye-Natural0
C105-heart-skeletal-occipital-hippocampus-acute-Sebocyte-penis0.158
C106-Hep2-epitheloid-placenta-cervical-rectal-anaplastic-glassy0
C107-Neutrophils-CD14-Eosinophils-Monocytederived-Whole-Peripheral-blood0
C108-breast-hepatoblastoma-MCF7-parotid-salivary-submaxillary-prostate0
C109-Reticulocytes-non-acute-Hodgkin-Burkitt-retinoblastoma-lymphoma0.464
C11-cerebellum-medulla-pons-parietal-occipital-middle-medial0
C110-leukemia-chronic-Eosinophils-acute-Whole-CD34-Lymphatic0
C111-medulla-lung-trachea-testis-caudate-epididymis-throat0
C112-gastric-pancreas-temporal-duodenum-small-extraskeletal-adrenal0
C113-thyroid-throat-lung-lymph-small-colon-trachea0
C114-teratocarcinoma-medulloblastoma-carcinosarcoma-iPS-anaplastic-acute-neuroblastoma0
C115-pituitary-Neural-caudate-putamen-amygdala-medulla-hippocampus0
C116-myeloma-xeroderma-tonsil-CD19-spleen-lymph-trachea0
C117-serous-clear-kidney-neuroectodermal-mesothelioma-endometrial-Intestinal0
C118-cerebellum-parietal-occipital-medial-middle-frontal-insula0
C119-CD4-CD8-Natural-Neutrophils-CD14-Peripheral-CD190
C12-Mast-Basophils-immature-chorionic-mature-CD14-Eosinophils0
C120-immature-salivary-tongue-skin-cervical-CD14-CD340
C121-NK-Natural-CD8-CD4-anaplastic-chronic-B0
C122-chronic-Reticulocytes-skeletal-leukemia-acute-colon-Tracheal0
C123-CD19-Natural-CD8-CD4-CD14-Peripheral-Basophils0
C124-small-temporal-duodenum-colon-gall-signet-Hepatocyte0
C125-mucinous-alveolar-mesothelioma-Smooth-lung-CD14-Nucleus0
C126-gastrointestinal-argyrophil-smallcell-merkel-bile-insula-brain0
C127-maxillary-small-hepatoblastoma-hepatocellular-alveolar-colon-argyrophil0
C128-testicular-choriocarcinoma-H9-teratocarcinoma-pancreatic-iPS-HES3GFP0
C129-liver-Hepatocyte-colon-duodenum-temporal-testicular-small0
C13-Neutrophils-Eosinophils-CD14-Monocytederived-Whole-Peripheral-CD40
C130-iPS-HES3GFP-H9-teratocarcinoma-testicular-colon-Alveolar0
C131-lung-trachea-Alveolar-thyroid-umbilical-throat-skin0
C132-acute-small-Dendritic-Macrophage-CD14-Neutrophils-Monocytederived0
C133-signet-gall-small-kidney-colon-ductal-adenocarcinoma0
C134-skeletal-diaphragm-tongue-throat-Skeletal-skin-penis0
C135-neuroblastoma-retinoblastoma-carcinoid-choriocarcinoma-testicular-acute-rectum0
C136-Wilms-extraskeletal-anaplastic-rhabdomyosarcoma-cholangiocellular-nonsmall-neuroectodermal0
C137-large-ductal-melanoma-cervical-Endothelial-Smooth-chronic0
C138-diffuse-Burkitt-lymphangiectasia-lymphoma-acute-CD19-pineal0
C139-astrocytoma-skin-salivary-gall-serous-Mallassezderived-renal0
C14-Whole-blood-Reticulocytes-liver-Neutrophils-Eosinophils-spleen0
C140-Renal-Endothelial-Hepatic-Lymphatic-heart-lung-spleen0
C141-Hodgkin-acute-thymus-chronic-vein-CD4-B0
C142-Preadipocyte-Fibroblast-hepatic-Ewing-Adipocyte-Olfactory-Hair0
C143-Monocytederived-CD14-Macrophage-Dendritic-Basophils-CD14CD16-Osteoblast0
C144-CD4-tonsil-NK-appendix-CD8-splenic-mycosis0
C145-neuroblastoma-peripheral-neuroectodermal-neuroepithelioma-carcinoid-adult-extraskeletal0
C146-lymphangiectasia-lymphoma-gall-lymph-tonsil-gastric-transitionalcell0
C147-Neutrophils-Eosinophils-CD4-CD14-CD8-Natural-Peripheral0
C148-kidney-small-epididymis-pancreas-serous-duodenum-temporal0
C149-occipital-medial-brain-amygdala-parietal-cerebral-cerebellum0
C15-anaplastic-small-skeletal-neuroblastoma-parietal-temporal-tongue0
C150-merkel-carcinoid-nonsmall-gastrointestinal-argyrophil-pineal-small0
C151-CD14-Natural-Basophils-CD8-Eosinophils-CD4-Mast0
C152-peripheral-neuroectodermal-neuroepithelioma-neuroblastoma-testicular-carcinoid-lung0
C153-rhabdomyosarcoma-liposarcoma-pancreatic-somatostatinoma-Reticulocytes-lymphoma-testicular0
C154-adenocarcinoma-Mesenchymal-Cardiac-small-sacrococcigeal-Smooth-Prostate0
C155-pituitary-placenta-nonsmall-cervical-smallcell-choriocarcinoma-epitheloid0
C156-plasma-splenic-hereditary-B-large-xeroderma-b0
C157-testicular-H9-testis-iPS-teratocarcinoma-colon-trachea0
C158-adrenal-gastric-temporal-parietal-duodenum-caudate-putamen0
C159-choriocarcinoma-pancreatic-placenta-chorionic-testicular-bronchioalveolar-seminal0
C16-medial-amygdala-occipital-parietal-olfactory-putamen-brain0
C160-medulla-Hepatocyte-retina-corpus-liver-pineal-cerebral0
C161-mesothelioma-Mesothelial-acute-mesenchymal-extraskeletal-renal-placenta0
C162-spinal-locus-medulla-substantia-thalamus-globus-diencephalon0
C163-Skeletal-skeletal-Pericytes-Hepatic-rhabdomyosarcoma-throat-mesenchymal0
C164-signet-corpus-optic-mucinous-substantia-salivary-choriocarcinoma0
C165-epithelioid-Adipocyte-mesothelioma-myxofibrosarcoma-lung-gastric-Mesothelial0
C166-Macrophage-Monocytederived-Dendritic-adipose-lymph-CD14-lung0
C167-Basophils-Mast-Eosinophils-Neutrophils-Peripheral-Whole-CD40
C168-Mast-CD14-immature-Basophils-Eosinophils-CD34-Peripheral0
C169-hereditary-adult-gall-lymphangiectasia-chronic-b-choriocarcinoma0
C17-Mast-CD14-Monocytederived-Lymphatic-Smooth-mesenchymal-Macrophage0
C170-epitheloid-cervical-Hep2-keratoacanthoma-adult-neuroblastoma-signet0
C171-merkel-neuroblastoma-pineal-retinoblastoma-carcinoid-small-eye0
C172-chorionic-skeletal-tongue-amniotic-liver-gastrointestinal-Pericytes0
C173-Adipocyte-mature-skin-left-Hepatocyte-Osteoblast-adipose0
C174-CD14-Neutrophils-Smooth-mesothelioma-embryonic-Monocytederived-Eosinophils0
C175-Eosinophils-Neutrophils-CD4-Basophils-CD19-CD8-Natural0
C176-Eosinophils-Neutrophils-Mast-CD14-CD4-Basophils-CD190.0265
C177-melanoma-Melanocyte-mesenchymal-retina-Mallassezderived-Gingival-squamous0
C178-spleen-liver-Hepatocyte-b-lymph-vein-thymus0
C179-CD19-Peripheral-lymphoma-blood-lymph-spleen-tonsil0
C18-CD4-CD8-thymus-Whole-Peripheral-Natural-blood0
C180-skeletal-heart-Hepatocyte-acute-occipital-hippocampus-middle0.157
C181-liposarcoma-somatostatinoma-neuroblastoma-mesothelioma-nonsmall-small-Alveolar0
C182-renal-mature-mesothelioma-lung-Mammary-Adipocyte-acute0
C183-acute-non-CD34-diffuse-CD133-myeloma-Burkitt0
C184-somatostatinoma-smallcell-nonsmall-small-gastrointestinal-pineal-thyroid0
C185-small-adrenal-gastric-Mesenchymal-acute-HES3GFP-testis0
C186-squamous-papillotubular-large-Tracheal-oral-Small-epidermoid0
C187-migratory-immature-Dendritic-CD19-CD14-Monocytederived-Macrophage0
C188-left-heart-tongue-skeletal-Skeletal-diaphragm-throat0
C189-b-splenic-tonsil-CD19-lymph-appendix-spleen0
C19-embryonic-testis-cord-chronic-CD14-NK-mesothelioma0
C190-colon-small-rectum-duodenum-appendix-temporal-oral0
C191-leiomyoblastoma-Mast-parietal-acute-bone-neuroepithelioma-embryonic0
C192-Neutrophils-CD14-Peripheral-Eosinophils-CD8-Natural-CD40
C193-Mesenchymal-Adipocyte-mature-Cardiac-heart-CD14CD16-CD140
C194-MCF7-breast-prostate-Intestinal-diffuse-Wilms-Alveolar0
C195-Small-Gingival-Bronchial-Smooth-mesenchymal-Urothelial-Tracheal0
C196-testicular-iPS-H9-teratocarcinoma-HES3GFP-choriocarcinoma-endometrial0
C197-tongue-esophagus-tonsil-salivary-cervix-nasal-Gingival0
C198-Mesenchymal-Hair-Hepatic-Fibroblast-Smooth-tenocyte-Pericytes0
C199-glioblastoma-B-osteosarcoma-Fibroblast-heart-rhabdomyosarcoma-myxofibrosarcoma0
C2-Eosinophils-Neutrophils-CD14-Whole-Basophils-Peripheral-Mast0
C20-heart-left-skeletal-diaphragm-tongue-umbilical-throat0
C200-seminal-Cardiac-Smooth-Hair-submaxillary-Neutrophils-mixed-0.0181
C201-colon-small-adenocarcinoma-duodenum-temporal-signet-gall0
C202-salivary-skin-penis-tongue-uterus-cervical-immature0
C203-acute-NK-chronic-CD133-lymphoma-immature-Dendritic0
C204-Smooth-nasal-CD4-CD19-CD8-CD14-CD340
C205-mycosis-cord-hairy-xeroderma-CD4-B-b0
C206-melanoma-somatostatinoma-nonsmall-small-neuroblastoma-smallcell-pituitary0
C207-Corneal-Keratinocyte-Esophageal-Mammary-Bronchial-Urothelial-Sebocyte0
C208-skin-amniotic-papillotubular-salivary-umbilical-Alveolar-serous0
C209-acute-myelodysplastic-CD34-granulocyte-CD133-liver-spleen0
C21-cord-mycosis-hairy-xeroderma-adult-CD4-anaplastic0
C210-Burkitt-lymphoma-appendix-acute-diffuse-CD19-tonsil0
C211-small-Hepatocyte-liver-colon-temporal-duodenum-kidney0
C212-chronic-acute-Whole-Reticulocytes-leukemia-blood-CD340.667
C213-CD14-Natural-CD8-CD4-Basophils-Eosinophils-Peripheral0
C214-Neurons-Neural-duodenum-temporal-occipital-parietal-brain0
C215-chronic-acute-peripheral-Hepatocyte-osteosarcoma-NK-immature0
C216-osteosarcoma-Smooth-Mesenchymal-large-neuroectodermal-acute-CD340
C217-carcinoid-neuroectodermal-mature-mesodermal-colon-acute-occipital0
C218-tonsil-lymph-CD19-spleen-colon-appendix-salivary0
C219-nasal-Basophils-amniotic-Melanocyte-CD14-Osteoblast-duodenum0
C22-CD4-CD8-Natural-Basophils-CD14-Peripheral-CD190
C220-Adipocyte-mature-left-breast-skin-liver-adipose0
C221-alveolar-Osteoblast-Myoblast-mesenchymal-liposarcoma-Smooth-hepatocellular0
C222-Melanocyte-Tracheal-Neutrophils-seminal-Smooth-Hair-Chondrocyte-0.0125
C223-Chondrocyte-basal-renal-Fibroblast-Smooth-spindle-Synoviocyte0
C224-clear-serous-pleomorphic-choriocarcinoma-mesothelioma-amniotic-renal0
C225-ductal-alveolar-giant-prostate-salivary-squamous-Tracheal0
C226-Corneal-Keratinocyte-Esophageal-Urothelial-Mammary-Bronchial-Tracheal0
C227-chorionic-amniotic-Mesenchymal-Placental-gastric-diaphragm-tongue0
C228-colon-Intestinal-Prostate-hepatoblastoma-hepatocellular-testis-adult0
C229-Mesenchymal-CD4-Melanocyte-acute-skeletal-left-heart0.0668
C23-CD4-CD8-Natural-Peripheral-Basophils-CD19-CD140
C230-aorta-normal-heart-penis-osteosarcoma-basal-lung0
C231-Mesothelial-mesenchymal-mesothelioma-Fibroblast-Preadipocyte-leiomyoma-mycosis0
C232-teratocarcinoma-HES3GFP-H9-iPS-testicular-neuroblastoma-cerebellum0
C233-uterus-cervix-ovary-epididymis-colon-rectum-MCF70
C234-oral-epidermoid-malignant-cervical-ductal-lung-keratoacanthoma0
C235-Intestinal-Prostate-liver-colon-small-kidney-pancreas0
C236-CD14-Neutrophils-Monocytederived-renal-Eosinophils-testis-mesothelioma0
C237-acute-breast-testicular-hepatoblastoma-chronic-argyrophil-Bronchial0.0344
C238-stomach-gall-breast-duodenum-temporal-MCF7-smallcell0
C239-CD4-lymphangiectasia-CD8-NK-mycosis-Renal-hairy0
C24-pineal-eye-retina-retinoblastoma-medulloblastoma-small-cerebral0
C240-Adipocyte-Preadipocyte-Osteoblast-Chondrocyte-tenocyte-Synoviocyte-mesenchymal0
C241-Reticulocytes-chronic-Tracheal-Hodgkin-Endothelial-Hair-thymus0.463
C242-acute-Chondrocyte-myelodysplastic-granulocyte-biphenotypic-Fibroblast-stomach0
C243-Chondrocyte-trachea-Synoviocyte-mesodermal-renal-Fibroblast-Ewing0
C244-CD14-Monocytederived-Hepatocyte-heart-Neutrophils-acute-Macrophage0
C245-prostate-penis-salivary-esophagus-kidney-Neutrophils-Pancreatic0
C246-Neutrophils-Eosinophils-Whole-CD14-CD14CD16-Basophils-migratory0.267
C247-pons-locus-medulla-spinal-paracentral-medial-occipital0
C248-iPS-Aortic-Hep2-amygdala-acute-medial-Myoblast0
C249-nonsmall-small-smallcell-occipital-somatostatinoma-maxillary-medial0
C25-small-colon-temporal-duodenum-liver-Hepatocyte-gall0
C250-Mast-Neutrophils-CD14-Eosinophils-CD8-Peripheral-CD40
C251-gall-tonsil-trachea-CD14-salivary-throat-tongue0
C252-hepatic-Olfactory-sacrococcigeal-leiomyoma-normal-Synoviocyte-glioblastoma0
C253-spleen-rhabdomyosarcoma-Hepatocyte-small-uterus-liver-rectum0
C254-prostate-rhabdomyosarcoma-seminal-Fibroblast-transitionalcell-Smooth-Iris0
C255-Wilms-leiomyoblastoma-kidney-adrenal-MCF7-epithelioid-Mast0
C256-occipital-caudate-amygdala-medial-thalamus-hippocampus-medulla0
C257-pineal-insula-frontal-occipital-temporal-medial-paracentral0
C258-hepatoblastoma-hepatocellular-signet-colon-Intestinal-Prostate-gastric0
C259-Preadipocyte-Adipocyte-Fibroblast-Chondrocyte-tenocyte-normal-Ewing0
C26-Eosinophils-Neutrophils-CD14-CD14CD16-Basophils-Monocytederived-Whole0
C260-acute-chronic-Natural-NK-Basophils-biphenotypic-blood0
C261-locus-medial-parietal-pons-diencephalon-olfactory-spinal0
C262-breast-MCF7-skeletal-Reticulocytes-mucinous-hepatoblastoma-Wilms0
C263-cervical-keratoacanthoma-tongue-skin-esophagus-throat-tonsil0
C264-giant-keratoacanthoma-colon-fibrosarcoma-HES3GFP-Hep2-acute0
C265-CD4-Eosinophils-CD14-Natural-CD19-Basophils-CD80
C266-acute-chronic-leukemia-small-choriocarcinoma-hepatoma-Mast0
C267-pancreatic-placenta-choriocarcinoma-testicular-teratocarcinoma-chorionic-clear0
C268-Mallassezderived-Urothelial-Gingival-Small-Bronchial-Tracheal-Prostate0
C269-Basophils-Mast-Eosinophils-mature-CD14-chorionic-CD40
C27-pancreas-temporal-duodenum-salivary-ductus-umbilical-lung0
C270-CD4-Fibroblast-acute-iPS-Aortic-CD34-Smooth0
C271-pineal-spinal-locus-globus-medulla-thalamus-cerebellum0
C272-CD19-CD4-CD8-Whole-Peripheral-lymph-tonsil0
C273-Neutrophils-CD14-Eosinophils-Monocytederived-CD4-Natural-Mast0
C274-CD14-Mast-immature-Basophils-mature-vagina-Hepatocyte0
C275-pons-medulla-cerebellum-locus-thalamus-diencephalon-spinal0
C276-mesothelioma-kidney-renal-small-clear-cerebellum-Renal0
C277-mesothelioma-epithelioid-thyroid-extraskeletal-alveolar-glioblastoma-adenocarcinoma0
C278-amygdala-hippocampus-insula-medial-putamen-temporal-olfactory0
C279-parietal-cerebellum-occipital-temporal-middle-duodenum-medial0
C28-thymus-acute-vein-Hodgkin-chronic-throat-Dendritic0
C280-Mast-Natural-CD19-CD8-Eosinophils-CD34-CD40
C281-Hodgkin-Reticulocytes-chronic-NK-acute-retinoblastoma-small0.393
C282-acute-B-tonsil-CD19-submaxillary-lymph-throat0
C283-tenocyte-Chondrocyte-mesenchymal-Macrophage-pleomorphic-Synoviocyte-cholangiocellular0
C284-parietal-occipital-medial-temporal-olfactory-locus-hippocampus0
C285-cervical-Hep2-small-colon-temporal-duodenum-bronchogenic0
C286-cerebellum-occipital-optic-parietal-globus-caudate-medial0
C287-Hepatocyte-Chondrocyte-Adipocyte-Synoviocyte-liver-tenocyte-mesenchymal0
C288-Chondrocyte-Renal-Pericytes-Fibroblast-aorta-Smooth-Meningeal0
C289-chorionic-skeletal-heart-Mast-amniotic-granulosa-left0
C29-mature-adipose-Adipocyte-breast-Lymphatic-vein-heart0
C290-Eosinophils-CD14-Basophils-Mast-CD4-CD8-immature0
C291-spinal-substantia-retina-medulla-tongue-skeletal-trachea0
C292-Mesenchymal-skin-umbilical-Adipocyte-mesenchymal-Chondrocyte-skeletal0
C293-CD14-CD14CD16-Basophils-Peripheral-immature-Eosinophils-CD340
C294-CD14-Macrophage-Monocytederived-CD14CD16-Neutrophils-Basophils-Peripheral0.0668
C295-Fibroblast-Smooth-Myoblast-Chondrocyte-hepatic-Synoviocyte-Preadipocyte0
C296-gall-small-mesothelioma-acute-bronchioalveolar-epidermoid-mixed0
C297-Eosinophils-CD4-Basophils-Natural-Neutrophils-CD8-Peripheral0
C298-small-optic-substantia-thalamus-diencephalon-globus-occipital0
C299-CD14CD16-Eosinophils-Neutrophils-CD14-Whole-Basophils-blood0.0668
C3-occipital-temporal-insula-medial-postcentral-frontal-amygdala0
C30-thyroid-throat-mesothelioma-mucinous-trachea-chorionic-mesenchymal0
C300-CD4-CD8-NK-Natural-blood-mycosis-Basophils0
C301-Smooth-mesenchymal-Endothelial-Hepatic-basal-hepatic-chorionic0
C302-acute-peripheral-Neutrophils-NK-myelodysplastic-CD34-carcinoid0
C303-CD14-Basophils-Peripheral-Eosinophils-CD14CD16-Neutrophils-Whole0
C305-heart-skeletal-smooth-left-bladder-penis-esophagus0
C31-skeletal-tongue-diaphragm-throat-penis-skin-trachea0
C32-middle-occipital-parietal-hippocampus-amygdala-medial-olfactory0
C33-Reticulocytes-liver-Whole-blood-chronic-acute-spleen0
C34-placenta-chorionic-choriocarcinoma-mesothelioma-Wilms-Smooth-bile0
C35-caudate-putamen-diencephalon-nucleus-globus-thalamus-insula0
C36-B-b-splenic-plasma-xeroderma-adrenal-Burkitt0
C37-salivary-submaxillary-parotid-seminal-tongue-ductus-trachea0
C38-extraskeletal-rhabdomyosarcoma-adrenal-rectal-mesothelioma-lung-Wilms0
C39-epididymis-ductus-seminal-testis-acute-thyroid-CD1330
C4-optic-corpus-substantia-medulla-spinal-thalamus-globus0
C40-eye-retina-Lens-pineal-tongue-retinoblastoma-small0
C41-retina-eye-medulla-Retinal-medulloblastoma-kidney-pineal0
C42-small-lung-maxillary-pharyngeal-Mesenchymal-Wilms-colon0
C43-ductus-seminal-duodenum-temporal-gall-prostate-bladder0
C44-Dendritic-CD19-CD133-granulocyte-acute-thymus-immature0
C45-testicular-choriocarcinoma-H9-teratocarcinoma-Wilms-pancreatic-iPS0
C46-acute-Hodgkin-thymus-CD8-chronic-CD4-merkel0
C47-CD19-Burkitt-acute-xeroderma-tonsil-lymphoma-appendix0
C48-smooth-bladder-esophagus-colon-penis-aorta-uterus0
C49-H9-iPS-testicular-HES3GFP-teratocarcinoma-hepatoblastoma-choriocarcinoma0
C5-Hepatocyte-liver-hepatocellular-Intestinal-kidney-small-pancreas0
C50-chorionic-placenta-amniotic-migratory-smallcell-chronic-choriocarcinoma0
C51-kidney-mesothelioma-renal-signet-gall-lung-pancreas0
C52-adult-NK-chronic-cord-testis-embryonic-myeloma0
C53-medulloblastoma-pineal-retinoblastoma-small-retina-eye-pituitary0
C54-Dendritic-Macrophage-Monocytederived-CD14-leiomyoma-adipose-immature0
C55-hepatocellular-Intestinal-liver-Prostate-fibrosarcoma-Hepatocyte-hepatoblastoma0
C56-heart-left-umbilical-skeletal-penis-diaphragm-tongue0
C57-Neutrophils-Eosinophils-Whole-CD4-CD8-CD19-Natural0.216
C58-Melanocyte-melanoma-retina-Retinal-eye-migratory-H90
C59-Smooth-Fibroblast-Mesenchymal-tenocyte-Ewing-skin-hepatic0
C6-CD14-Eosinophils-Basophils-Peripheral-CD34-Natural-immature0
C60-esophagus-tonsil-throat-tongue-uterus-cervix-cervical0
C61-migratory-Dendritic-immature-Macrophage-xeroderma-cord-b0
C62-Burkitt-tonsil-CD19-submaxillary-spleen-salivary-lymph0
C63-neuroectodermal-neuroblastoma-carcinoid-peripheral-chronic-neuroepithelioma-acute0
C64-Mast-chronic-acute-immature-chorionic-Basophils-Dendritic0
C65-CD14-Eosinophils-Monocytederived-Basophils-immature-Macrophage-Neutrophils0
C66-cerebellum-middle-occipital-parietal-medial-amygdala-hippocampus0
C67-CD14-Monocytederived-Macrophage-dura-Dendritic-spleen-lung0
C68-amniotic-chorionic-Placental-salivary-placenta-tongue-mesothelioma0
C69-anaplastic-CD14-cord-hairy-mycosis-adult-NK0
C7-CD14-Eosinophils-Neutrophils-Smooth-Basophils-Macrophage-Mast0
C70-parotid-submaxillary-salivary-throat-trachea-aorta-tongue0
C71-Monocytederived-Macrophage-CD14-Dendritic-Osteoblast-leiomyoma-Prostate0
C72-skeletal-tongue-throat-heart-diaphragm-penis-left0
C73-pineal-eye-retina-caudate-cerebellum-left-parietal0
C74-splenic-B-b-plasma-xeroderma-lymphoma-hairy0
C75-Eosinophils-Natural-CD8-Basophils-CD14-CD4-Peripheral0
C76-argyrophil-gastrointestinal-temporal-duodenum-neuroblastoma-merkel-smallcell0
C77-Saos2-osteosarcoma-Neutrophils-Natural-Chondrocyte-Basophils-CD80
C78-lymphoma-plasma-tonsil-appendix-lymph-seminal-trachea0
C79-chorionic-Chondrocyte-Cardiac-Smooth-Fibroblast-Preadipocyte-Mesenchymal0
C8-Natural-CD8-Basophils-CD4-CD14-Peripheral-CD340
C80-immature-migratory-CD14-Dendritic-splenic-cord-Mast0
C81-trachea-salivary-throat-aorta-eye-submaxillary-parotid0
C82-Basophils-CD14-Eosinophils-Natural-Peripheral-immature-CD340
C83-choriocarcinoma-pancreatic-placenta-chorionic-HES3GFP-testicular-amniotic0
C84-choriocarcinoma-pancreatic-Wilms-Mallassezderived-thymus-salivary-colon0
C85-neuroblastoma-carcinoid-retinoblastoma-small-pineal-rhabdomyosarcoma-medulloblastoma0
C86-colon-carcinoid-small-neuroectodermal-giant-large-neuroepithelioma0
C87-retinoblastoma-left-nonsmall-heart-small-diaphragm-bronchogenic0
C88-Melanocyte-melanoma-Macrophage-Mesenchymal-migratory-Dendritic-Monocytederived0
C89-small-retinoblastoma-medulloblastoma-iPS-acantholytic-eye-bronchogenic0
C9-skeletal-diaphragm-tongue-throat-penis-heart-left0
C90-neuroectodermal-peripheral-neuroepithelioma-neuroblastoma-carcinoid-parietal-putamen0
C91-Fibroblast-Smooth-mesenchymal-Mesothelial-Small-Preadipocyte-Hair0
C92-CD14CD16-CD14-Eosinophils-Basophils-Neutrophils-Macrophage-Whole0
C93-chronic-acute-leukemia-acantholytic-medulloblastoma-testis-papillotubular0
C94-smallcell-adrenal-lung-nonsmall-small-somatostatinoma-teratocarcinoma0
C95-lung-aorta-trachea-penis-Alveolar-throat-endometrioid0
C96-non-acute-tonsil-spleen-Burkitt-lymphoma-appendix0
C97-small-smallcell-gastrointestinal-argyrophil-putamen-duodenum-brain0
C98-CD8-Natural-Basophils-blood-CD4-Peripheral-Whole0
C99-hairy-mycosis-submaxillary-salivary-cord-kidney-parotid0



Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data



TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample


JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs11865

Jaspar motifP-value
MA0002.20.0468
MA0003.10.639
MA0004.10.0265
MA0006.10.347
MA0007.10.374
MA0009.10.119
MA0014.10.377
MA0017.10.021
MA0018.26.34631e-4
MA0019.10.252
MA0024.14.09819e-5
MA0025.10.162
MA0027.10.309
MA0028.13.64506e-8
MA0029.10.00348
MA0030.10.328
MA0031.10.815
MA0035.21.07742e-26
MA0038.10.00478
MA0039.20.807
MA0040.10.0519
MA0041.10.588
MA0042.10.723
MA0043.10.00863
MA0046.10.378
MA0047.20.24
MA0048.10.296
MA0050.10.688
MA0051.10.433
MA0052.17.41457e-6
MA0055.10.0431
MA0057.10.383
MA0058.10.036
MA0059.10.00136
MA0060.10.111
MA0061.10.893
MA0062.21.2231e-12
MA0065.20.0114
MA0066.10.993
MA0067.10.819
MA0068.10.114
MA0069.10.198
MA0070.10.997
MA0071.10.051
MA0072.10.551
MA0073.10.492
MA0074.10.459
MA0076.11.43931e-7
MA0077.10.317
MA0078.10.72
MA0079.20.974
MA0080.22.39504e-8
MA0081.10.00858
MA0083.10.00494
MA0084.10.36
MA0087.10.145
MA0088.10.00209
MA0090.10.00113
MA0091.10.761
MA0092.10.939
MA0093.10.0371
MA0099.24.30153e-7
MA0100.11.24685e-4
MA0101.10.358
MA0102.20.152
MA0103.10.551
MA0104.21.4395e-4
MA0105.10.153
MA0106.10.924
MA0107.10.0652
MA0108.24.56464e-7
MA0111.10.167
MA0112.20.235
MA0113.10.836
MA0114.10.0374
MA0115.10.12
MA0116.10.00657
MA0117.10.497
MA0119.10.839
MA0122.10.534
MA0124.10.366
MA0125.10.25
MA0131.10.521
MA0135.10.994
MA0136.13.49565e-9
MA0137.20.523
MA0138.20.766
MA0139.10.971
MA0140.11.38422e-33
MA0141.10.161
MA0142.10.532
MA0143.10.319
MA0144.10.955
MA0145.10.475
MA0146.10.024
MA0147.13.53317e-5
MA0148.10.0616
MA0149.10.0444
MA0150.10.348
MA0152.10.192
MA0153.10.0443
MA0154.10.363
MA0155.10.933
MA0156.11.69085e-8
MA0157.10.93
MA0159.10.512
MA0160.10.0354
MA0162.10.849
MA0163.16.05192e-12
MA0164.10.819
MA0258.10.209
MA0259.10.0682



FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs11865

Novel motifP-value
10.0686
100.0158
1000.66
1010.668
1020.374
1030.184
1040.673
1050.575
1060.976
1070.828
1080.581
1090.0125
110.0487
1100.396
1110.0318
1120.399
1130.581
1140.134
1150.135
1160.103
1170.0442
1180.132
1190.355
120.774
1200.59
1210.7
1220.937
1230.00784
1240.576
1250.0738
1260.544
1270.0865
1280.887
1290.721
130.00524
1300.565
1310.38
1320.659
1330.0449
1340.67
1350.396
1360.0588
1370.939
1380.951
1390.6
140.741
1400.505
1410.293
1420.434
1430.142
1440.692
1450.731
1460.801
1470.0513
1480.956
1490.167
150.235
1500.812
1510.816
1520.677
1530.842
1540.816
1550.0715
1560.819
1570.442
1580.601
1590.0968
160.957
1600.432
1610.287
1620.873
1630.284
1640.0938
1650.438
1660.163
1670.456
1680.861
1690.548
170.97
180.203
190.923
20.515
200.222
210.343
220.656
230.017
240.37
250.322
260.0938
270.948
280.738
290.0185
30.174
300.00941
310.368
320.0143
330.408
340.758
350.663
360.0335
370.271
380.364
390.42
40.294
400.315
410.345
420.396
430.62
440.791
450.686
460.321
470.0539
480.13
490.263
50.919
500.662
510.532
520.764
530.267
540.549
550.198
560.868
570.207
580.159
590.639
60.409
600.558
610.151
620.309
630.614
640.234
650.807
660.0264
670.992
680.123
690.824
70.0494
700.984
710.168
720.433
730.398
740.322
750.0118
760.161
770.376
780.00288
790.00635
80.134
800.49
810.553
820.33
830.576
840.591
850.0353
860.913
870.0219
880.198
890.687
90.93
900.0905
910.753
920.62
930.834
940.7
950.00407
960.635
970.448
980.0465
990.469



de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br> library id: CNhs11865


FANTOM5 (FF) ontology


Direct parent terms


Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data

CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000255 (eukaryotic cell)

DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
2531 (hematologic cancer)
14566 (disease of cellular proliferation)
0060083 (immune system cancer)
1240 (leukemia)
8692 (myeloid leukemia)
8552 (chronic myeloid leukemia)

FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100737 (leukemia cell line sample)
0101035 (hematopoietic cell line sample)
0100740 (myeloid leukemia cell line sample)

Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)