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{{f5samples
{{f5samples
|id=FF:10801-110I9
|DRA_sample_Accession=CAGE@SAMD00005470
|name=chronic myeloblastic leukemia (CML) cell line:KCL-22
|accession_numbers=CAGE;DRX007853;DRR008725;DRZ000150;DRZ001535;DRZ011500;DRZ012885
|sample_id=10801
|ancestors_in_anatomy_facet=
|rna_tube_id=110I9
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000255
|rna_box=110
|ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:2531,DOID:14566,DOID:0060083,DOID:1240,DOID:1036,DOID:8692
|rna_position=I9
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100737,FF:0102580,FF:0101035,FF:0100740,FF:0104137
|sample_cell_lot=
|comment=
|sample_cell_catalog=jcrb1317
|created_by=
|sample_company=JAPAN HEALTH SCIENCES FOUNDATION - Health Science Research Resources Bank
|creation_date=
|rna_lot_number=
|data_phase=2
|rna_catalog_number=
|datafreeze_phase=2
|sample_species=Human (Homo sapiens)
|def=
|sample_strain=
|expression_enrichment_score=chr3:128212033..128212051,-!p1@GATA2!2.78!595.11!GATA2;;chr2:219849012..219849065,-!p1@FEV!2.42!260.27!FEV;;chr8:116673894..116673913,-!p12@TRPS1!2.02!103.76!TRPS1;;chr12:54694758..54694805,-!p1@NFE2!1.90!94.19!NFE2;;chr6:135502501..135502546,+!p1@MYB!1.86!84.46!MYB;;chr2:219849175..219849187,-!p4@FEV!1.82!64.36!FEV;;chr21:39870339..39870443,-!p1@ERG!1.79!61.22!ERG;;chr9:135854091..135854159,+!p1@GFI1B!1.77!57.77!GFI1B;;chr2:68592406..68592424,+!p1@PLEK!1.72!51.02!PLEK;;chr12:54694807..54694832,-!p3@NFE2!1.67!46.00!NFE2;;chr19:13213511..13213545,-!p2@LYL1!1.62!43.80!LYL1;;chr6:135502408..135502459,+!p2@MYB!1.61!46.15!MYB;;chr8:60031619..60031676,-!p1@TOX!1.59!79.12!TOX;;chr11:47400078..47400106,-!p1@SPI1!1.56!35.48!SPI1;;chr11:113930425..113930471,+!p1@ZBTB16!1.55!48.51!ZBTB16;;chr7:50344289..50344323,+!p1@IKZF1!1.55!34.38!IKZF1;;chrX:2418949..2419024,-!p1@DHRSX,p1@ZBED1!1.52!32.02!ZBED1;;chr8:116681108..116681120,-!p9@TRPS1!1.51!39.09!TRPS1;;chr1:25291475..25291511,-!p2@RUNX3!1.49!29.83!RUNX3;;chr7:115670804..115670825,-!p1@TFEC!1.46!27.63!TFEC;;chr3:128206762..128206781,-!p2@GATA2!1.37!134.22!GATA2;;chr19:33793430..33793447,-!p1@CEBPA!1.35!88.38!CEBPA;;chr8:116680833..116680881,-!p7@TRPS1!1.32!30.30!TRPS1;;chr1:92951607..92951661,-!p1@GFI1!1.32!20.09!GFI1;;chr9:20382446..20382493,-!p4@MLLT3!1.31!19.47!MLLT3;;chr8:60031934..60031986,-!p6@TOX!1.30!19.15!TOX;;chr5:88178983..88179012,-!p1@MEF2C!1.28!135.16!MEF2C;;chr20:62680984..62680999,-!p1@SOX18!1.27!23.39!SOX18;;chr8:116681123..116681143,-!p4@TRPS1!1.26!32.97!TRPS1;;chr11:47399947..47399961,-!p3@SPI1!1.24!16.33!SPI1;;chr13:72441315..72441454,-!p1@DACH1!1.23!32.02!DACH1;;chr6:135502472..135502489,+!p3@MYB!1.20!14.91!MYB;;chr3:18486354..18486377,-!p2@SATB1!1.18!17.58!SATB1;;chr11:47399996..47400014,-!p4@SPI1!1.18!14.13!SPI1;;chr8:60031682..60031710,-!p2@TOX!1.17!22.45!TOX;;chr8:128747846..128747860,+!p15@MYC!1.17!13.81!MYC;;chr7:50343634..50343717,+!p2@IKZF1!1.16!13.50!IKZF1;;chr8:116681409..116681431,-!p2@TRPS1!1.15!35.79!TRPS1;;chr2:219849078..219849085,-!p10@FEV!1.15!13.19!FEV;;chr14:75988771..75988826,+!p1@BATF!1.14!17.11!BATF;;chr1:47697539..47697573,-!p3@TAL1!1.14!12.72!TAL1;;chr18:77155922..77155939,+!p1@NFATC1!1.09!30.93!NFATC1;;chr8:60031762..60031803,-!p3@TOX!1.09!16.33!TOX;;chr2:60780607..60780624,-!p2@BCL11A!1.08!34.22!BCL11A;;chr8:60031809..60031835,-!p4@TOX!1.08!13.97!TOX;;chr21:36421535..36421610,-!p2@RUNX1!1.07!39.09!RUNX1;;chr4:109090075..109090095,-!p2@LEF1!1.07!10.83!LEF1;;chr8:60031840..60031869,-!p5@TOX!1.07!10.83!TOX;;chr6:100061724..100061753,+!p1@PRDM13!1.06!10.52!PRDM13;;chr10:131762504..131762555,-!p1@EBF3!1.06!10.36!EBF3;;chr7:44143925..44143970,+!p1@AEBP1!1.05!227.46!AEBP1;;chr10:94449703..94449718,+!p1@HHEX!1.05!39.56!HHEX;;chr7:44143978..44143989,+!p2@AEBP1!1.05!18.68!AEBP1;;chr19:13213662..13213686,-!p1@LYL1!1.05!15.38!LYL1;;chr7:137620650..137620677,-!p3@CREB3L2!1.04!9.89!CREB3L2;;chr7:50344251..50344288,+!p3@IKZF1!1.04!9.89!IKZF1;;chr8:145669791..145669834,-!p1@TONSL!1.02!27.63!TONSL;;chr11:47400032..47400043,-!p5@SPI1!1.01!9.26!SPI1;;chr12:11802547..11802560,+!p5@ETV6!1.00!12.56!ETV6;;chrX:48644984..48645005,+!p1@GATA1!1.00!9.10!GATA1;;chr1:47695003..47695042,-!p2@TAL1!0.98!8.48!TAL1;;chr2:145277640..145277771,-!p1@ZEB2!0.97!115.54!ZEB2;;chr12:54694738..54694749,-!p5@NFE2!0.97!8.32!NFE2;;chr20:31350184..31350200,+!p1@DNMT3B!0.96!17.11!DNMT3B;;chr11:113930291..113930339,+!p2@ZBTB16!0.96!13.66!ZBTB16;;chr2:219849897..219849928,-!p2@FEV!0.95!7.85!FEV;;chr13:41593425..41593480,-!p1@ELF1!0.94!50.39!ELF1;;chr7:44143997..44144008,+!p3@AEBP1!0.94!9.89!AEBP1;;chr14:23588242..23588262,-!p1@CEBPE!0.94!7.69!CEBPE;;chr11:128563948..128564003,+!p1@FLI1!0.91!89.32!FLI1;;chr9:2015335..2015370,+!p1@SMARCA2!0.90!89.32!SMARCA2;;chr11:47400045..47400060,-!p6@SPI1!0.90!6.91!SPI1;;chr12:54694653..54694672,-!p2@NFE2!0.90!6.91!NFE2;;chr19:13213555..13213568,-!p5@LYL1!0.90!6.91!LYL1;;chr11:113930401..113930422,+!p3@ZBTB16!0.89!6.75!ZBTB16;;chr1:25256756..25256774,-!p1@RUNX3!0.88!12.87!RUNX3;;chr17:79881332..79881348,-!p3@MAFG!0.87!9.58!MAFG;;chr1:221052994..221053008,+!p6@HLX!0.87!7.69!HLX;;chr11:47400062..47400077,-!p2@SPI1!0.87!6.44!SPI1;;chr10:94449675..94449694,+!p2@HHEX!0.86!17.42!HHEX;;chr2:102091566..102091581,-!p1@RFX8!0.86!6.28!RFX8;;chr8:116680215..116680245,-!p6@TRPS1!0.85!9.89!TRPS1;;chr8:128748308..128748324,+!p2@MYC!0.84!177.07!MYC;;chr11:32457075..32457095,-!p1@WT1!0.84!5.97!WT1;;chr8:22550982..22550999,-!p1@EGR3!0.83!17.27!EGR3;;chr11:61520075..61520136,+!p1@C11orf9!0.83!12.72!C11orf9;;chr19:13213465..13213478,-!p7@LYL1!0.83!5.81!LYL1;;chr6:20402102..20402152,+!p1@E2F3!0.82!24.33!E2F3;;chr7:128577972..128578047,+!p1@IRF5!0.82!9.10!IRF5;;chr1:158985493..158985535,+!p4@IFI16!0.82!8.79!IFI16;;chr7:137620684..137620711,-!p4@CREB3L2!0.82!5.65!CREB3L2;;chr20:42295745..42295765,+!p1@MYBL2!0.81!95.44!MYBL2;;chr16:68119324..68119364,+!p1@NFATC3!0.81!26.37!NFATC3;;chr16:29819446..29819471,+!p9@MAZ!0.81!17.27!MAZ;;chr2:219849213..219849224,-!p6@FEV!0.81!5.49!FEV;;chr10:31288398..31288455,-!p2@ZNF438!0.80!6.28!ZNF438;;chr2:219849008..219849011,-!p13@FEV!0.80!5.34!FEV;;chr2:68592394..68592405,+!p2@PLEK!0.80!5.34!PLEK;;chr1:47691303..47691319,-!p5@TAL1!0.80!5.34!TAL1;;chr19:22817119..22817145,+!p1@ZNF492!0.79!9.10!ZNF492;;chr1:205649614..205649663,-!p1@SLC45A3,p5@ELK4!0.79!8.95!ELK4;;chr17:42295682..42295731,-!p17@UBTF!0.79!5.18!UBTF;;chr9:124976328..124976372,-!p2@LHX6!0.79!5.18!LHX6;;chr19:45579725..45579743,-!p1@ZNF296!0.78!24.49!ZNF296;;chr4:109089901..109089930,-!p3@LEF1!0.78!5.02!LEF1;;chr20:50159198..50159299,-!p1@NFATC2!0.77!7.38!NFATC2;;chr6:15401104..15401166,+!p5@JARID2!0.77!4.87!JARID2;;chr7:50348268..50348366,+!p4@IKZF1!0.77!4.87!IKZF1;;chr2:219849805..219849819,-!p3@FEV!0.77!4.87!FEV;;chr6:144329500..144329526,-!p4@PLAGL1!0.76!11.93!PLAGL1;;chr2:185463247..185463263,+!p1@ZNF804A!0.76!8.95!ZNF804A;;chr17:42295777..42295816,-!p7@UBTF!0.76!5.81!UBTF;;chr1:47696918..47696935,-!p6@TAL1!0.76!4.71!TAL1;;chr6:144385698..144385742,-!p2@PLAGL1!0.75!5.81!PLAGL1;;chr11:47279504..47279563,+!p1@NR1H3!0.74!10.99!NR1H3;;chr11:32457103..32457123,-!p3@WT1!0.74!4.55!WT1;;chr19:13213399..13213414,-!p6@LYL1!0.74!4.55!LYL1;;chr4:113437332..113437337,-!p1@NEUROG2!0.74!4.55!NEUROG2;;chr1:158979686..158979745,+!p1@IFI16!0.73!159.33!IFI16;;chr19:52074502..52074587,+!p1@ZNF175!0.73!17.27!ZNF175;;chr13:72441074..72441172,-!p2@DACH1!0.73!4.40!DACH1;;chr6:144329384..144329405,-!p1@PLAGL1!0.72!55.57!PLAGL1;;chr1:247171316..247171336,-!p3@ZNF695!0.72!6.59!ZNF695;;chr5:88179017..88179046,-!p2@MEF2C!0.71!18.37!MEF2C;;chr2:66662249..66662267,+!p2@MEIS1!0.71!17.74!MEIS1;;chr1:47697439..47697457,-!p9@TAL1!0.71!4.08!TAL1;;chr14:75988831..75988847,+!p2@BATF!0.71!4.08!BATF;;chr2:60780753..60780800,-!p1@BCL11A!0.70!22.45!BCL11A;;chr21:36260980..36261011,-!p1@RUNX1!0.69!130.14!RUNX1;;chr3:141747459..141747475,-!p1@TFDP2!0.69!36.73!TFDP2;;chr6:15246200..15246214,+!p2@JARID2!0.69!11.93!JARID2;;chr9:2015306..2015323,+!p3@SMARCA2!0.69!11.30!SMARCA2;;chr1:221052733..221052749,+!p2@HLX!0.69!5.34!HLX;;chr17:46622205..46622218,-!p3@HOXB2!0.69!4.55!HOXB2;;chr6:100061760..100061774,+!p2@PRDM13!0.69!3.92!PRDM13;;chr6:21593973..21593988,+!p1@SOX4!0.68!157.77!SOX4;;chr20:42295713..42295738,+!p2@MYBL2!0.68!25.59!MYBL2;;chr2:66662281..66662308,+!p1@MEIS1!0.68!14.60!MEIS1;;chr19:45579762..45579772,-!p2@ZNF296!0.68!4.24!ZNF296;;chr11:113930477..113930488,+!p4@ZBTB16!0.68!3.77!ZBTB16;;chr12:54778471..54778528,-!p1@ZNF385A!0.68!3.77!ZNF385A;;chr19:23299814..23299844,+!p1@ZNF730!0.67!4.71!ZNF730;;chr8:116681686..116681699,-!p23@TRPS1!0.66!3.61!TRPS1;;chr3:128207349..128207386,-!p3@GATA2!0.66!3.61!GATA2;;chr8:128747661..128747703,+!p6@MYC!0.65!4.87!MYC;;chr6:135513595..135513617,+!p4@MYB!0.65!3.45!MYB;;chr4:109087445..109087463,-!p1@LEF1!0.65!3.45!LEF1;;chr17:40440481..40440550,+!p1@STAT5A!0.64!28.57!STAT5A;;chr19:21265028..21265052,+!p2@ZNF714!0.64!6.59!ZNF714;;chr1:221052776..221052799,+!p1@HLX!0.64!6.59!HLX;;chrX:66763856..66763896,+!p1@AR!0.64!5.18!AR;;chr22:29196547..29196563,-!p2@XBP1!0.63!144.74!XBP1;;chr15:57210961..57211012,+!p3@TCF12!0.63!11.93!TCF12;;chr19:35455110..35455149,-!p1@ZNF792!0.63!7.06!ZNF792;;chr17:46622229..46622257,-!p6@HOXB2!0.63!3.92!HOXB2;;chr19:57352087..57352102,-!p1@PEG3,p1@ZIM2!0.63!3.30!PEG3;;chr8:60031563..60031574,-!p7@TOX!0.63!3.30!TOX;;chr19:45971246..45971265,+!p1@FOSB!0.62!71.43!FOSB;;chr8:128747757..128747800,+!p7@MYC!0.62!4.55!MYC;;chr2:185463521..185463557,+!p3@ZNF804A!0.62!3.14!ZNF804A;;chr4:109089436..109089456,-!p22@LEF1!0.62!3.14!LEF1;;chr9:135854168..135854179,+!p5@GFI1B!0.62!3.14!GFI1B;;chr17:48072574..48072597,-!p1@DLX3!0.62!3.14!DLX3;;chr1:156470515..156470542,-!p2@MEF2D!0.61!18.99!MEF2D;;chr17:41277372..41277418,-!p1@BRCA1!0.61!13.03!BRCA1;;chr5:138647473..138647476,+!p6@MATR3!0.61!8.79!MATR3;;chr13:36871902..36872023,-!p1@CCDC169-SOHLH2,p1@CCDC169,p1@SOHLH2!0.61!7.54!SOHLH2;;chr1:247171347..247171366,-!p2@ZNF695!0.61!6.28!ZNF695;;chr8:116681247..116681261,-!p8@TRPS1!0.60!4.08!TRPS1;;chr6:28304275..28304282,-!p7@ZNF323!0.60!2.98!ZNF323;;chr21:36421147..36421193,-!p10@RUNX1!0.60!2.98!RUNX1;;chr3:63953435..63953499,+!p1@ATXN7!0.60!2.98!ATXN7;;chr4:109088940..109089037,-!p4@LEF1!0.60!2.98!LEF1;;chr9:117150254..117150271,-!p1@AKNA!0.59!9.10!AKNA;;chr10:35484053..35484076,+!p1@CREM!0.59!8.32!CREM;;chr6:144329531..144329546,-!p5@PLAGL1!0.59!5.02!PLAGL1;;chr5:138609782..138609826,+!p5@MATR3!0.58!22.29!MATR3;;chr8:116681150..116681164,-!p5@TRPS1!0.58!6.12!TRPS1;;chr2:60778035..60778060,-!p4@BCL11A!0.58!3.45!BCL11A;;chr7:44143738..44143760,+!p4@AEBP1!0.58!3.30!AEBP1;;chr7:115670792..115670797,-!p2@TFEC!0.58!2.83!TFEC;;chr8:116681878..116681893,-!p15@TRPS1!0.58!2.83!TRPS1;;chr2:60781201..60781258,-!p3@BCL11A!0.58!2.83!BCL11A;;chr4:57522598..57522664,-!p3@HOPX!0.58!2.83!HOPX;;chr4:57522674..57522699,-!p5@HOPX!0.58!2.83!HOPX;;chr1:158985457..158985468,+!p12@IFI16!0.58!2.83!IFI16;;chr21:36421347..36421380,-!p8@RUNX1!0.58!2.83!RUNX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|sample_dev_stage=
|ffid_belonging_in_development=CL:0000049,CL:0000134
|sample_tissue=blood
|sample_donor(cell lot)=
|sample_sex=female
|sample_age=28
|sample_ethnicity=J
|rna_rin=
|rna_od260/230=2.11
|rna_od260/280=2.07
|sample_cell_type=granulocyte monocyte progenitor cell
|sample_cell_line=KCL-22
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest)
|sample_experimental_condition=
|sample_disease=chronic myeloblastic leukemia (CML)
|rna_sample_type=total RNA
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0
|rna_weight_ug=20.88153
|rna_concentration=0.77339
|sample_note=
|profile_hcage=CNhs11886,LSID830,release010,COMPLETED
|profile_cagescan=,,,
|profile_srnaseq=,,,
|profile_rnaseq=,,,
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000004,CL:0000012,CL:0000034,CL:0000037,CL:0000048,CL:0000049,CL:0000063,CL:0000134,CL:0000144,CL:0000219,CL:0000255,CL:0000548,CL:0000566,CL:0000723,CL:0000763,CL:0000837,CL:0000988,CL:0002032,CL:0002320,CL:0002371
|ancestors_in_anatomy_facet=UBERON:0000061,UBERON:0000465,UBERON:0000479,UBERON:0001062,UBERON:0002384
|ancestors_in_disease_facet=DOID:0050686,DOID:0060083,DOID:1036,DOID:1240,DOID:14566,DOID:162,DOID:2531,DOID:4,DOID:8692
|sample_description=
|fonse_cell_line=FF:0101035
|fonse_cell_line=FF:0101035
|fonse_cell_line_closure=FF:0101035
|fonse_cell_line_closure=FF:0101035
Line 66: Line 40:
|fonse_treatment=
|fonse_treatment=
|fonse_treatment_closure=
|fonse_treatment_closure=
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|name=chronic myeloblastic leukemia (CML) cell line:KCL-22
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|rna_box=110
|rna_catalog_number=
|rna_concentration=0.77339
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0
|rna_lot_number=
|rna_od260/230=2.11
|rna_od260/280=2.07
|rna_position=I9
|rna_rin=
|rna_sample_type=total RNA
|rna_tube_id=110I9
|rna_weight_ug=20.88153
|sample_age=28
|sample_category=cell lines
|sample_cell_catalog=jcrb1317
|sample_cell_line=KCL-22
|sample_cell_lot=
|sample_cell_type=granulocyte monocyte progenitor cell
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest)
|sample_company=JAPAN HEALTH SCIENCES FOUNDATION - Health Science Research Resources Bank
|sample_description=
|sample_dev_stage=
|sample_disease=chronic myeloblastic leukemia (CML)
|sample_donor(cell lot)=
|sample_ethnicity=J
|sample_experimental_condition=
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;5.87990559079812e-246!GO:0043227;membrane-bound organelle;5.25778696900095e-218!GO:0043231;intracellular membrane-bound organelle;1.12176620976705e-217!GO:0043226;organelle;2.4731007432217e-203!GO:0043229;intracellular organelle;7.25465093448755e-203!GO:0005737;cytoplasm;6.63637024685857e-167!GO:0044422;organelle part;1.90712780375646e-151!GO:0044446;intracellular organelle part;8.5950460184614e-150!GO:0044444;cytoplasmic part;6.89836815964827e-122!GO:0044237;cellular metabolic process;6.29319540324883e-116!GO:0032991;macromolecular complex;9.76215724380027e-113!GO:0044238;primary metabolic process;1.31481198260758e-112!GO:0043170;macromolecule metabolic process;3.61821376947868e-104!GO:0005634;nucleus;6.48522535030857e-100!GO:0030529;ribonucleoprotein complex;7.73462406706473e-98!GO:0043233;organelle lumen;4.33134130626999e-92!GO:0031974;membrane-enclosed lumen;4.33134130626999e-92!GO:0044428;nuclear part;5.1982275625457e-92!GO:0003723;RNA binding;1.66916303526576e-81!GO:0005739;mitochondrion;1.12502788539934e-79!GO:0005515;protein binding;3.54691657443712e-68!GO:0043283;biopolymer metabolic process;2.93845739575174e-64!GO:0006396;RNA processing;1.23946807540316e-60!GO:0006412;translation;9.71968821421262e-60!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;7.63830207930306e-58!GO:0010467;gene expression;2.91593661233502e-57!GO:0005840;ribosome;5.32717141803102e-57!GO:0031981;nuclear lumen;1.5014735256947e-56!GO:0043234;protein complex;4.00580284507308e-56!GO:0044429;mitochondrial part;2.25165243235476e-55!GO:0019538;protein metabolic process;5.16054128536682e-53!GO:0003735;structural constituent of ribosome;6.8082065937027e-50!GO:0044249;cellular biosynthetic process;1.25976160588988e-49!GO:0009058;biosynthetic process;1.79130263908223e-49!GO:0031967;organelle envelope;4.76225398619852e-49!GO:0031975;envelope;1.22601702365446e-48!GO:0016071;mRNA metabolic process;4.020443647166e-48!GO:0044267;cellular protein metabolic process;1.82189325665976e-47!GO:0044260;cellular macromolecule metabolic process;3.82788528154928e-47!GO:0031090;organelle membrane;5.9627359474099e-46!GO:0009059;macromolecule biosynthetic process;1.9640316140777e-45!GO:0008380;RNA splicing;3.19976811248988e-43!GO:0033279;ribosomal subunit;5.15285764439325e-42!GO:0016043;cellular component organization and biogenesis;7.67786895649001e-42!GO:0033036;macromolecule localization;1.18623597072776e-41!GO:0006259;DNA metabolic process;1.3404622410516e-41!GO:0006397;mRNA processing;2.06771919296616e-41!GO:0015031;protein transport;1.00698392881932e-40!GO:0005829;cytosol;9.15218026613037e-38!GO:0045184;establishment of protein localization;1.17171030013586e-37!GO:0008104;protein localization;2.26703699939368e-37!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.08987804882844e-36!GO:0065003;macromolecular complex assembly;3.42752993176669e-36!GO:0046907;intracellular transport;1.0593134241558e-35!GO:0005654;nucleoplasm;7.04634859389345e-35!GO:0003676;nucleic acid binding;2.18412200695248e-34!GO:0005740;mitochondrial envelope;3.19482558077364e-34!GO:0006996;organelle organization and biogenesis;9.58141760791288e-34!GO:0019866;organelle inner membrane;1.14983936374402e-32!GO:0007049;cell cycle;1.82180451184086e-32!GO:0031966;mitochondrial membrane;9.22731297515712e-32!GO:0022607;cellular component assembly;2.56105446427553e-31!GO:0006886;intracellular protein transport;4.83378016712262e-31!GO:0005681;spliceosome;6.38247477738977e-31!GO:0043228;non-membrane-bound organelle;1.34046307009563e-29!GO:0043232;intracellular non-membrane-bound organelle;1.34046307009563e-29!GO:0005743;mitochondrial inner membrane;1.80526925695527e-29!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.98713082877659e-29!GO:0000166;nucleotide binding;3.01077516866133e-29!GO:0016070;RNA metabolic process;3.1334183174874e-27!GO:0044451;nucleoplasm part;9.05749851292513e-27!GO:0022402;cell cycle process;7.90198392261746e-26!GO:0051649;establishment of cellular localization;3.13177725842645e-25!GO:0031980;mitochondrial lumen;5.50079403397038e-25!GO:0005759;mitochondrial matrix;5.50079403397038e-25!GO:0006974;response to DNA damage stimulus;5.50079403397038e-25!GO:0051641;cellular localization;1.45306382168311e-24!GO:0006119;oxidative phosphorylation;2.26604123491297e-24!GO:0044455;mitochondrial membrane part;2.34597744073315e-24!GO:0044445;cytosolic part;3.48900668766672e-24!GO:0000278;mitotic cell cycle;1.48682307724968e-23!GO:0005730;nucleolus;3.86357401694845e-23!GO:0016462;pyrophosphatase activity;6.59638399615999e-23!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;7.5272797096891e-23!GO:0016817;hydrolase activity, acting on acid anhydrides;1.08717661713343e-22!GO:0006281;DNA repair;8.1298359738442e-22!GO:0017111;nucleoside-triphosphatase activity;8.70179631271162e-22!GO:0015935;small ribosomal subunit;9.43659628161215e-22!GO:0015934;large ribosomal subunit;1.95464806559129e-21!GO:0005694;chromosome;3.37448638009334e-21!GO:0032553;ribonucleotide binding;2.21593510882807e-20!GO:0032555;purine ribonucleotide binding;2.21593510882807e-20!GO:0017076;purine nucleotide binding;5.96612862019817e-20!GO:0051276;chromosome organization and biogenesis;6.07642041473942e-20!GO:0022618;protein-RNA complex assembly;1.21372115798958e-19!GO:0016874;ligase activity;2.73240421141171e-19!GO:0005524;ATP binding;4.58345609991188e-19!GO:0005746;mitochondrial respiratory chain;1.05564035036431e-18!GO:0032559;adenyl ribonucleotide binding;1.253790096059e-18!GO:0044427;chromosomal part;1.35927804235571e-18!GO:0044265;cellular macromolecule catabolic process;1.50652596337505e-18!GO:0006457;protein folding;1.86681048215564e-18!GO:0006512;ubiquitin cycle;2.7102307652076e-18!GO:0000087;M phase of mitotic cell cycle;3.79565478371373e-18!GO:0030554;adenyl nucleotide binding;5.64981685051615e-18!GO:0022403;cell cycle phase;5.72765394395638e-18!GO:0009719;response to endogenous stimulus;8.26894874644495e-18!GO:0007067;mitosis;1.07662385296631e-17!GO:0042254;ribosome biogenesis and assembly;1.38767964171779e-17!GO:0048770;pigment granule;4.73724058110423e-17!GO:0042470;melanosome;4.73724058110423e-17!GO:0043412;biopolymer modification;5.53740327926074e-17!GO:0006605;protein targeting;5.74104787110864e-17!GO:0005761;mitochondrial ribosome;5.74104787110864e-17!GO:0000313;organellar ribosome;5.74104787110864e-17!GO:0050136;NADH dehydrogenase (quinone) activity;7.80169814142024e-17!GO:0003954;NADH dehydrogenase activity;7.80169814142024e-17!GO:0008137;NADH dehydrogenase (ubiquinone) activity;7.80169814142024e-17!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;1.1159021831738e-16!GO:0051301;cell division;1.23467349581375e-16!GO:0051186;cofactor metabolic process;1.4197816900105e-16!GO:0006260;DNA replication;1.74676560525201e-16!GO:0043285;biopolymer catabolic process;2.22113199896994e-16!GO:0012505;endomembrane system;2.83136696997948e-16!GO:0008134;transcription factor binding;3.61170104826289e-16!GO:0000398;nuclear mRNA splicing, via spliceosome;3.86496119677409e-16!GO:0000375;RNA splicing, via transesterification reactions;3.86496119677409e-16!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;3.86496119677409e-16!GO:0006325;establishment and/or maintenance of chromatin architecture;3.9228892141953e-16!GO:0009057;macromolecule catabolic process;4.43548841247778e-16!GO:0044248;cellular catabolic process;6.18390638469789e-16!GO:0000502;proteasome complex (sensu Eukaryota);8.59995122920389e-16!GO:0016887;ATPase activity;1.02111076996869e-15!GO:0044453;nuclear membrane part;1.22416443024228e-15!GO:0005635;nuclear envelope;1.4225751513814e-15!GO:0006323;DNA packaging;1.6943686730516e-15!GO:0042623;ATPase activity, coupled;2.24823784782385e-15!GO:0012501;programmed cell death;3.31728851197846e-15!GO:0006915;apoptosis;3.31728851197846e-15!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);4.58483748755515e-15!GO:0008135;translation factor activity, nucleic acid binding;4.6579802260375e-15!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);7.72414607200859e-15!GO:0031965;nuclear membrane;7.76880731387556e-15!GO:0030964;NADH dehydrogenase complex (quinone);8.34993646194555e-15!GO:0045271;respiratory chain complex I;8.34993646194555e-15!GO:0005747;mitochondrial respiratory chain complex I;8.34993646194555e-15!GO:0042775;organelle ATP synthesis coupled electron transport;8.34993646194555e-15!GO:0042773;ATP synthesis coupled electron transport;8.34993646194555e-15!GO:0016604;nuclear body;9.18507730861922e-15!GO:0051726;regulation of cell cycle;9.43584580711806e-15!GO:0006464;protein modification process;1.30898164390613e-14!GO:0051603;proteolysis involved in cellular protein catabolic process;1.95095582973602e-14!GO:0006511;ubiquitin-dependent protein catabolic process;2.12666144089337e-14!GO:0000279;M phase;2.17154127144428e-14!GO:0019941;modification-dependent protein catabolic process;2.30885059653019e-14!GO:0043632;modification-dependent macromolecule catabolic process;2.30885059653019e-14!GO:0006732;coenzyme metabolic process;2.59322987647601e-14!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;2.61874573724665e-14!GO:0000074;regulation of progression through cell cycle;2.91209389485135e-14!GO:0044257;cellular protein catabolic process;3.76049963675866e-14!GO:0005783;endoplasmic reticulum;4.16472427287875e-14!GO:0044432;endoplasmic reticulum part;1.31542043588519e-13!GO:0006913;nucleocytoplasmic transport;1.43739668245726e-13!GO:0008219;cell death;1.79691931699252e-13!GO:0016265;death;1.79691931699252e-13!GO:0043687;post-translational protein modification;3.97770314925609e-13!GO:0051169;nuclear transport;4.23202222090066e-13!GO:0005643;nuclear pore;5.03909212965909e-13!GO:0050657;nucleic acid transport;5.39335414837837e-13!GO:0051236;establishment of RNA localization;5.39335414837837e-13!GO:0050658;RNA transport;5.39335414837837e-13!GO:0065002;intracellular protein transport across a membrane;5.92947017016296e-13!GO:0006399;tRNA metabolic process;6.29129536868843e-13!GO:0006403;RNA localization;8.1150343978683e-13!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.25472630698646e-12!GO:0006413;translational initiation;4.03386052845849e-12!GO:0003743;translation initiation factor activity;4.52787547434031e-12!GO:0030163;protein catabolic process;4.95986132227646e-12!GO:0051082;unfolded protein binding;5.11745846655922e-12!GO:0009259;ribonucleotide metabolic process;5.55183591898042e-12!GO:0004386;helicase activity;6.30240838574119e-12!GO:0006364;rRNA processing;7.71178495313683e-12!GO:0006163;purine nucleotide metabolic process;8.92087313471732e-12!GO:0000785;chromatin;9.20310846783643e-12!GO:0016072;rRNA metabolic process;1.32122305928645e-11!GO:0006446;regulation of translational initiation;1.40041983415161e-11!GO:0065004;protein-DNA complex assembly;1.71853250569086e-11!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;2.0702065517841e-11!GO:0016568;chromatin modification;2.23706593787292e-11!GO:0008565;protein transporter activity;2.29768967769679e-11!GO:0016607;nuclear speck;2.58958922951562e-11!GO:0006164;purine nucleotide biosynthetic process;2.65074392242234e-11!GO:0046930;pore complex;5.87388420290812e-11!GO:0051028;mRNA transport;6.08390583407284e-11!GO:0017038;protein import;6.91895851789013e-11!GO:0009260;ribonucleotide biosynthetic process;7.27521813952591e-11!GO:0008026;ATP-dependent helicase activity;8.12496412724588e-11!GO:0006366;transcription from RNA polymerase II promoter;9.69174511532835e-11!GO:0009150;purine ribonucleotide metabolic process;1.01396305792638e-10!GO:0016740;transferase activity;1.17209144316273e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.78300702655541e-10!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.79152997508367e-10!GO:0006333;chromatin assembly or disassembly;1.87436522394796e-10!GO:0050794;regulation of cellular process;2.51111621616369e-10!GO:0048193;Golgi vesicle transport;2.61595162980362e-10!GO:0009152;purine ribonucleotide biosynthetic process;3.08261465364901e-10!GO:0003712;transcription cofactor activity;3.39423178552927e-10!GO:0006461;protein complex assembly;4.6898799699982e-10!GO:0016192;vesicle-mediated transport;4.82185170711168e-10!GO:0042175;nuclear envelope-endoplasmic reticulum network;5.27169889268024e-10!GO:0006793;phosphorus metabolic process;5.27169889268024e-10!GO:0006796;phosphate metabolic process;5.27169889268024e-10!GO:0051188;cofactor biosynthetic process;5.59301898848983e-10!GO:0030532;small nuclear ribonucleoprotein complex;6.28774409423786e-10!GO:0005789;endoplasmic reticulum membrane;1.11566785140212e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;1.20914618058054e-09!GO:0042981;regulation of apoptosis;1.23745819063552e-09!GO:0009055;electron carrier activity;1.3042511721597e-09!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;1.48601692829092e-09!GO:0004812;aminoacyl-tRNA ligase activity;1.48601692829092e-09!GO:0016875;ligase activity, forming carbon-oxygen bonds;1.48601692829092e-09!GO:0043067;regulation of programmed cell death;1.89053036967182e-09!GO:0019829;cation-transporting ATPase activity;2.40780940599004e-09!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;2.49311127394098e-09!GO:0009056;catabolic process;2.73011172997797e-09!GO:0051246;regulation of protein metabolic process;3.36049477947887e-09!GO:0043038;amino acid activation;3.38155479738949e-09!GO:0006418;tRNA aminoacylation for protein translation;3.38155479738949e-09!GO:0043039;tRNA aminoacylation;3.38155479738949e-09!GO:0009199;ribonucleoside triphosphate metabolic process;3.69363526597692e-09!GO:0009141;nucleoside triphosphate metabolic process;4.26115419872842e-09!GO:0009142;nucleoside triphosphate biosynthetic process;4.88594259646e-09!GO:0009201;ribonucleoside triphosphate biosynthetic process;4.88594259646e-09!GO:0009060;aerobic respiration;4.97446428443379e-09!GO:0007005;mitochondrion organization and biogenesis;5.00541316136234e-09!GO:0015986;ATP synthesis coupled proton transport;6.10232981984914e-09!GO:0015985;energy coupled proton transport, down electrochemical gradient;6.10232981984914e-09!GO:0009205;purine ribonucleoside triphosphate metabolic process;6.94269308614212e-09!GO:0009144;purine nucleoside triphosphate metabolic process;6.94269308614212e-09!GO:0016779;nucleotidyltransferase activity;8.01777191089711e-09!GO:0048523;negative regulation of cellular process;8.93345825443737e-09!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;9.41795068638271e-09!GO:0009145;purine nucleoside triphosphate biosynthetic process;9.41795068638271e-09!GO:0008639;small protein conjugating enzyme activity;9.66324284307974e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;1.50882007616475e-08!GO:0006261;DNA-dependent DNA replication;1.81301180197358e-08!GO:0004842;ubiquitin-protein ligase activity;2.15115462540146e-08!GO:0019787;small conjugating protein ligase activity;2.27513680217646e-08!GO:0009108;coenzyme biosynthetic process;2.3717752059496e-08!GO:0045333;cellular respiration;3.1449522698713e-08!GO:0043566;structure-specific DNA binding;3.35842063170148e-08!GO:0005793;ER-Golgi intermediate compartment;5.13452063065691e-08!GO:0016310;phosphorylation;5.31656289167407e-08!GO:0051170;nuclear import;6.70456692871137e-08!GO:0005794;Golgi apparatus;7.06677043216355e-08!GO:0046034;ATP metabolic process;7.71741602200147e-08!GO:0003899;DNA-directed RNA polymerase activity;7.71741602200147e-08!GO:0016787;hydrolase activity;7.98578114086244e-08!GO:0006754;ATP biosynthetic process;8.24976680761384e-08!GO:0006753;nucleoside phosphate metabolic process;8.24976680761384e-08!GO:0009117;nucleotide metabolic process;1.35195601687366e-07!GO:0019222;regulation of metabolic process;1.42514488390182e-07!GO:0006334;nucleosome assembly;1.50593324261366e-07!GO:0005819;spindle;1.5327519944608e-07!GO:0006606;protein import into nucleus;1.62998935707641e-07!GO:0006099;tricarboxylic acid cycle;1.68115808963504e-07!GO:0046356;acetyl-CoA catabolic process;1.68115808963504e-07!GO:0015078;hydrogen ion transmembrane transporter activity;1.73890359913473e-07!GO:0043069;negative regulation of programmed cell death;1.80341314023438e-07!GO:0003697;single-stranded DNA binding;1.92433715725053e-07!GO:0016469;proton-transporting two-sector ATPase complex;2.0331417446592e-07!GO:0043066;negative regulation of apoptosis;2.07098057874789e-07!GO:0050789;regulation of biological process;2.445667285479e-07!GO:0006752;group transfer coenzyme metabolic process;2.9109153597515e-07!GO:0031497;chromatin assembly;3.04832897503599e-07!GO:0006084;acetyl-CoA metabolic process;3.17562809186341e-07!GO:0006916;anti-apoptosis;3.2192125798737e-07!GO:0007249;I-kappaB kinase/NF-kappaB cascade;3.35158414189732e-07!GO:0000245;spliceosome assembly;3.45512027397803e-07!GO:0016881;acid-amino acid ligase activity;3.59788370357728e-07!GO:0048519;negative regulation of biological process;3.81054426926334e-07!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;4.21733596385494e-07!GO:0005667;transcription factor complex;4.78392390424964e-07!GO:0051329;interphase of mitotic cell cycle;4.98225887678544e-07!GO:0045259;proton-transporting ATP synthase complex;5.13766692707969e-07!GO:0003713;transcription coactivator activity;7.23830078308879e-07!GO:0051325;interphase;8.014476946224e-07!GO:0005839;proteasome core complex (sensu Eukaryota);8.10026089560265e-07!GO:0045786;negative regulation of progression through cell cycle;9.9810902275088e-07!GO:0009109;coenzyme catabolic process;1.22787052849181e-06!GO:0032446;protein modification by small protein conjugation;1.337818569333e-06!GO:0048475;coated membrane;1.59604741285745e-06!GO:0030117;membrane coat;1.59604741285745e-06!GO:0000775;chromosome, pericentric region;1.66982358237483e-06!GO:0000075;cell cycle checkpoint;2.17077938567988e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;2.31881341244855e-06!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;2.40376148338088e-06!GO:0016567;protein ubiquitination;2.97295826909314e-06!GO:0015630;microtubule cytoskeleton;3.24982854070893e-06!GO:0005762;mitochondrial large ribosomal subunit;3.25358267915363e-06!GO:0000315;organellar large ribosomal subunit;3.25358267915363e-06!GO:0004298;threonine endopeptidase activity;3.26950376688413e-06!GO:0005768;endosome;3.27540752931745e-06!GO:0051427;hormone receptor binding;3.50597856557988e-06!GO:0016491;oxidoreductase activity;4.16828766375787e-06!GO:0003724;RNA helicase activity;5.2008808043542e-06!GO:0006613;cotranslational protein targeting to membrane;5.63378888395392e-06!GO:0006888;ER to Golgi vesicle-mediated transport;5.9165815713264e-06!GO:0016563;transcription activator activity;6.42412725213591e-06!GO:0051187;cofactor catabolic process;6.55889436237684e-06!GO:0005788;endoplasmic reticulum lumen;6.7476613464269e-06!GO:0044452;nucleolar part;6.99948142959898e-06!GO:0035257;nuclear hormone receptor binding;7.33770703385357e-06!GO:0016772;transferase activity, transferring phosphorus-containing groups;7.78481456953249e-06!GO:0007051;spindle organization and biogenesis;8.35618612680991e-06!GO:0008094;DNA-dependent ATPase activity;8.43095113398247e-06!GO:0006401;RNA catabolic process;8.82468609806764e-06!GO:0000151;ubiquitin ligase complex;9.36690707640368e-06!GO:0016741;transferase activity, transferring one-carbon groups;9.5976622926036e-06!GO:0006950;response to stress;9.68876325200553e-06!GO:0008168;methyltransferase activity;9.85864977870667e-06!GO:0005815;microtubule organizing center;1.20529498013625e-05!GO:0006302;double-strand break repair;1.36771476007158e-05!GO:0051168;nuclear export;1.38743930599738e-05!GO:0005773;vacuole;1.4001208068026e-05!GO:0030880;RNA polymerase complex;1.44474170568633e-05!GO:0008654;phospholipid biosynthetic process;1.49966741949412e-05!GO:0000314;organellar small ribosomal subunit;1.56487064982999e-05!GO:0005763;mitochondrial small ribosomal subunit;1.56487064982999e-05!GO:0031323;regulation of cellular metabolic process;1.68046267532697e-05!GO:0006839;mitochondrial transport;1.7348821640119e-05!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;1.76865463399369e-05!GO:0016853;isomerase activity;1.86497735312961e-05!GO:0005813;centrosome;1.92709129482791e-05!GO:0043623;cellular protein complex assembly;1.94070502057458e-05!GO:0031324;negative regulation of cellular metabolic process;1.9798856398907e-05!GO:0006352;transcription initiation;1.98860927206474e-05!GO:0005657;replication fork;2.11513687773041e-05!GO:0000323;lytic vacuole;2.17082495881565e-05!GO:0005764;lysosome;2.17082495881565e-05!GO:0015077;monovalent inorganic cation transmembrane transporter activity;2.30630769603494e-05!GO:0006383;transcription from RNA polymerase III promoter;2.39997153959631e-05!GO:0045454;cell redox homeostasis;2.98981038575579e-05!GO:0016363;nuclear matrix;3.11830039305869e-05!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;3.30078670803875e-05!GO:0015399;primary active transmembrane transporter activity;3.30078670803875e-05!GO:0019752;carboxylic acid metabolic process;3.35828601759954e-05!GO:0009165;nucleotide biosynthetic process;3.45875611806686e-05!GO:0007243;protein kinase cascade;3.46460631911853e-05!GO:0055029;nuclear DNA-directed RNA polymerase complex;3.62034940234302e-05!GO:0000428;DNA-directed RNA polymerase complex;3.62034940234302e-05!GO:0006082;organic acid metabolic process;3.91126669073081e-05!GO:0043021;ribonucleoprotein binding;4.1995527213449e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;4.34805344247562e-05!GO:0030120;vesicle coat;4.66200934639952e-05!GO:0030662;coated vesicle membrane;4.66200934639952e-05!GO:0008033;tRNA processing;5.12266980762825e-05!GO:0003690;double-stranded DNA binding;5.55884612542065e-05!GO:0005770;late endosome;5.58362816505296e-05!GO:0006091;generation of precursor metabolites and energy;5.66107962955479e-05!GO:0006310;DNA recombination;6.07183332854676e-05!GO:0006626;protein targeting to mitochondrion;6.22036573473547e-05!GO:0031968;organelle outer membrane;6.36764221008439e-05!GO:0003678;DNA helicase activity;6.49179324869449e-05!GO:0003684;damaged DNA binding;6.55868515964258e-05!GO:0016564;transcription repressor activity;6.56210570073392e-05!GO:0019867;outer membrane;7.03366728576361e-05!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;7.32639211112744e-05!GO:0003924;GTPase activity;8.68543942060756e-05!GO:0019899;enzyme binding;9.5484096990252e-05!GO:0005741;mitochondrial outer membrane;0.000103859320662461!GO:0006350;transcription;0.000120282353759639!GO:0006414;translational elongation;0.000120404335889914!GO:0004527;exonuclease activity;0.000124142611561842!GO:0043681;protein import into mitochondrion;0.000124871837133673!GO:0006402;mRNA catabolic process;0.000132472535164932!GO:0003729;mRNA binding;0.000142921454902339!GO:0005525;GTP binding;0.000145263826508967!GO:0000059;protein import into nucleus, docking;0.00015446959842126!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00016291329914195!GO:0006520;amino acid metabolic process;0.000164837107984802!GO:0007088;regulation of mitosis;0.000173512500722147!GO:0000786;nucleosome;0.000173823634841733!GO:0065007;biological regulation;0.000186024477985835!GO:0030867;rough endoplasmic reticulum membrane;0.00019285562465147!GO:0008186;RNA-dependent ATPase activity;0.00019983936080464!GO:0006417;regulation of translation;0.000201271726435961!GO:0031988;membrane-bound vesicle;0.000223770690691076!GO:0005885;Arp2/3 protein complex;0.000223770690691076!GO:0007059;chromosome segregation;0.000236114673817649!GO:0009892;negative regulation of metabolic process;0.00026503959596771!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.000267667031317387!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000287572072441901!GO:0005798;Golgi-associated vesicle;0.000288849519977356!GO:0006612;protein targeting to membrane;0.000311728503176914!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000330354291298139!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.000342393643205741!GO:0005637;nuclear inner membrane;0.000400448428481985!GO:0015992;proton transport;0.000406992881159216!GO:0006818;hydrogen transport;0.000427352436712704!GO:0015980;energy derivation by oxidation of organic compounds;0.000428726648323947!GO:0000082;G1/S transition of mitotic cell cycle;0.000432171106816974!GO:0044440;endosomal part;0.0004328174251061!GO:0010008;endosome membrane;0.0004328174251061!GO:0016023;cytoplasmic membrane-bound vesicle;0.000437794393171612!GO:0046483;heterocycle metabolic process;0.000450691497956542!GO:0043492;ATPase activity, coupled to movement of substances;0.000458895184280052!GO:0007006;mitochondrial membrane organization and biogenesis;0.000466312174387606!GO:0065009;regulation of a molecular function;0.000467139478864451!GO:0000776;kinetochore;0.000476417306060045!GO:0010468;regulation of gene expression;0.000486054878782099!GO:0016481;negative regulation of transcription;0.000490703929415435!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.000492259507684223!GO:0031982;vesicle;0.000502974333852908!GO:0016251;general RNA polymerase II transcription factor activity;0.000509703385706493!GO:0046474;glycerophospholipid biosynthetic process;0.000509703385706493!GO:0004518;nuclease activity;0.000522611075485132!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000523755003223216!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000540500029147705!GO:0004004;ATP-dependent RNA helicase activity;0.000584099213522373!GO:0051052;regulation of DNA metabolic process;0.000602011152165261!GO:0016281;eukaryotic translation initiation factor 4F complex;0.000606271758330805!GO:0003682;chromatin binding;0.000671421932749328!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000722588119031841!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00079661608000565!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00079661608000565!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00079661608000565!GO:0051920;peroxiredoxin activity;0.000892970268026344!GO:0008632;apoptotic program;0.000948363034407777!GO:0007093;mitotic cell cycle checkpoint;0.000986493833108724!GO:0006367;transcription initiation from RNA polymerase II promoter;0.000986674742443054!GO:0005684;U2-dependent spliceosome;0.000997124016654338!GO:0006405;RNA export from nucleus;0.00104314202241921!GO:0031410;cytoplasmic vesicle;0.00108386042928688!GO:0006519;amino acid and derivative metabolic process;0.00111737618659191!GO:0044262;cellular carbohydrate metabolic process;0.00114428049960578!GO:0031326;regulation of cellular biosynthetic process;0.00116465908389594!GO:0051087;chaperone binding;0.00121699182626205!GO:0005769;early endosome;0.00130169806829212!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.00132028518756952!GO:0046489;phosphoinositide biosynthetic process;0.00133566466818651!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00139131698699208!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00139131698699208!GO:0032508;DNA duplex unwinding;0.00139131698699208!GO:0032392;DNA geometric change;0.00139131698699208!GO:0000049;tRNA binding;0.00143560052803793!GO:0030119;AP-type membrane coat adaptor complex;0.0015337764158292!GO:0048500;signal recognition particle;0.00157186783053036!GO:0000287;magnesium ion binding;0.00170644134749079!GO:0007052;mitotic spindle organization and biogenesis;0.00177866601338692!GO:0016859;cis-trans isomerase activity;0.00182783492651106!GO:0030118;clathrin coat;0.00183617666839651!GO:0044431;Golgi apparatus part;0.00187934536431991!GO:0051252;regulation of RNA metabolic process;0.00193121294246831!GO:0009112;nucleobase metabolic process;0.0019621426286689!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0019621426286689!GO:0032561;guanyl ribonucleotide binding;0.00203945240325394!GO:0019001;guanyl nucleotide binding;0.00203945240325394!GO:0022890;inorganic cation transmembrane transporter activity;0.00204331717493935!GO:0003714;transcription corepressor activity;0.00206966094407344!GO:0046467;membrane lipid biosynthetic process;0.00207320699378367!GO:0007050;cell cycle arrest;0.00208122862081794!GO:0005048;signal sequence binding;0.00220494896722324!GO:0030521;androgen receptor signaling pathway;0.00238599017130084!GO:0015036;disulfide oxidoreductase activity;0.0025800220504938!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00258619071333055!GO:0008312;7S RNA binding;0.00260002493550782!GO:0006270;DNA replication initiation;0.00263232116709486!GO:0030131;clathrin adaptor complex;0.00264038325124558!GO:0004576;oligosaccharyl transferase activity;0.00264038325124558!GO:0042802;identical protein binding;0.00271110891729075!GO:0006268;DNA unwinding during replication;0.00272904432932185!GO:0008610;lipid biosynthetic process;0.00276052638223794!GO:0043065;positive regulation of apoptosis;0.00281091158857638!GO:0006611;protein export from nucleus;0.00284616833069218!GO:0009889;regulation of biosynthetic process;0.00285621841804629!GO:0047485;protein N-terminus binding;0.00291286070957946!GO:0030384;phosphoinositide metabolic process;0.00294481249809459!GO:0009967;positive regulation of signal transduction;0.00311087995009935!GO:0006338;chromatin remodeling;0.00312273223897581!GO:0031072;heat shock protein binding;0.00313242089225255!GO:0043068;positive regulation of programmed cell death;0.00332118174699392!GO:0035258;steroid hormone receptor binding;0.00334293410766676!GO:0004674;protein serine/threonine kinase activity;0.00340694155157628!GO:0051539;4 iron, 4 sulfur cluster binding;0.00348516062928315!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.00349271756398133!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00351205717845966!GO:0045047;protein targeting to ER;0.00351205717845966!GO:0000922;spindle pole;0.00351205717845966!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00352560396969152!GO:0006595;polyamine metabolic process;0.00355054828162901!GO:0008047;enzyme activator activity;0.00358811853722164!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.00369418047868254!GO:0006650;glycerophospholipid metabolic process;0.00378767524113602!GO:0003711;transcription elongation regulator activity;0.00399345234795727!GO:0032259;methylation;0.00402443191476871!GO:0032200;telomere organization and biogenesis;0.00413420883913223!GO:0000723;telomere maintenance;0.00413420883913223!GO:0031124;mRNA 3'-end processing;0.00414476827956457!GO:0043284;biopolymer biosynthetic process;0.00432878831332844!GO:0043488;regulation of mRNA stability;0.00436487878848729!GO:0043487;regulation of RNA stability;0.00436487878848729!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00436515694617413!GO:0030518;steroid hormone receptor signaling pathway;0.00437708052764886!GO:0005774;vacuolar membrane;0.00439805396180397!GO:0009116;nucleoside metabolic process;0.00440838541541065!GO:0008287;protein serine/threonine phosphatase complex;0.00465000031323031!GO:0032774;RNA biosynthetic process;0.00470833058732444!GO:0043414;biopolymer methylation;0.00474291942455364!GO:0008250;oligosaccharyl transferase complex;0.00476763144017248!GO:0006144;purine base metabolic process;0.00478970563901732!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0049945691121784!GO:0019843;rRNA binding;0.00505427153751465!GO:0005758;mitochondrial intermembrane space;0.00518648588300031!GO:0005791;rough endoplasmic reticulum;0.00534781998802448!GO:0006351;transcription, DNA-dependent;0.00554606725111034!GO:0030176;integral to endoplasmic reticulum membrane;0.00559354260293721!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00562937136657746!GO:0048522;positive regulation of cellular process;0.00572133595022538!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00585788911533207!GO:0000096;sulfur amino acid metabolic process;0.00594142243765806!GO:0004003;ATP-dependent DNA helicase activity;0.00597805507234229!GO:0000792;heterochromatin;0.00615791273506489!GO:0000178;exosome (RNase complex);0.00628053774187864!GO:0006284;base-excision repair;0.00644575126262959!GO:0051540;metal cluster binding;0.00650638792251408!GO:0051536;iron-sulfur cluster binding;0.00650638792251408!GO:0016272;prefoldin complex;0.00664237676325482!GO:0006275;regulation of DNA replication;0.00682766444146997!GO:0003725;double-stranded RNA binding;0.00711899630619872!GO:0042393;histone binding;0.00723531173028901!GO:0006807;nitrogen compound metabolic process;0.0073597628428098!GO:0003677;DNA binding;0.00746408633238111!GO:0004177;aminopeptidase activity;0.0075845703083842!GO:0008276;protein methyltransferase activity;0.0075845703083842!GO:0008408;3'-5' exonuclease activity;0.00759313268323731!GO:0000339;RNA cap binding;0.00759313268323731!GO:0009451;RNA modification;0.00759313268323731!GO:0033116;ER-Golgi intermediate compartment membrane;0.00777772303016899!GO:0006917;induction of apoptosis;0.0080081593152831!GO:0005669;transcription factor TFIID complex;0.00835279014571417!GO:0015631;tubulin binding;0.00884531024976142!GO:0004532;exoribonuclease activity;0.00884676191475677!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.00884676191475677!GO:0048487;beta-tubulin binding;0.00897644544088529!GO:0009308;amine metabolic process;0.00927536094066099!GO:0006740;NADPH regeneration;0.00935211449196847!GO:0006098;pentose-phosphate shunt;0.00935211449196847!GO:0009303;rRNA transcription;0.00935211449196847!GO:0006730;one-carbon compound metabolic process;0.00935211449196847!GO:0009124;nucleoside monophosphate biosynthetic process;0.00935211449196847!GO:0009123;nucleoside monophosphate metabolic process;0.00935211449196847!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00935211449196847!GO:0015002;heme-copper terminal oxidase activity;0.00935211449196847!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00935211449196847!GO:0004129;cytochrome-c oxidase activity;0.00935211449196847!GO:0031252;leading edge;0.00935211449196847!GO:0043022;ribosome binding;0.00939310115248878!GO:0007242;intracellular signaling cascade;0.00940647590413452!GO:0006220;pyrimidine nucleotide metabolic process;0.00944168000962942!GO:0006289;nucleotide-excision repair;0.00948469269768907!GO:0016311;dephosphorylation;0.00965224775962542!GO:0006891;intra-Golgi vesicle-mediated transport;0.00974142080024793!GO:0050662;coenzyme binding;0.00975737702483026!GO:0030522;intracellular receptor-mediated signaling pathway;0.00982190753582145!GO:0009081;branched chain family amino acid metabolic process;0.00994466045917197!GO:0044437;vacuolar part;0.0099855405874638!GO:0050790;regulation of catalytic activity;0.0101178849387916!GO:0006509;membrane protein ectodomain proteolysis;0.0101530716961327!GO:0033619;membrane protein proteolysis;0.0101530716961327!GO:0005832;chaperonin-containing T-complex;0.0101832558826476!GO:0012502;induction of programmed cell death;0.0102207984265606!GO:0004722;protein serine/threonine phosphatase activity;0.010429531313297!GO:0022415;viral reproductive process;0.0106981131577345!GO:0030041;actin filament polymerization;0.0107200654608716!GO:0031970;organelle envelope lumen;0.0108978648302215!GO:0005765;lysosomal membrane;0.0110319153611242!GO:0006506;GPI anchor biosynthetic process;0.01120208468705!GO:0030663;COPI coated vesicle membrane;0.0116416585344817!GO:0030126;COPI vesicle coat;0.0116416585344817!GO:0046128;purine ribonucleoside metabolic process;0.0116692532735492!GO:0042278;purine nucleoside metabolic process;0.0116692532735492!GO:0031123;RNA 3'-end processing;0.0117390989316888!GO:0045892;negative regulation of transcription, DNA-dependent;0.0117614412156371!GO:0007264;small GTPase mediated signal transduction;0.0118984788575815!GO:0006378;mRNA polyadenylation;0.0119200852187689!GO:0008139;nuclear localization sequence binding;0.0121279452070271!GO:0032984;macromolecular complex disassembly;0.0124118746548644!GO:0018196;peptidyl-asparagine modification;0.0125831247963872!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0125831247963872!GO:0005876;spindle microtubule;0.0128052276049754!GO:0051287;NAD binding;0.0130839093887056!GO:0051789;response to protein stimulus;0.0131624655498269!GO:0006986;response to unfolded protein;0.0131624655498269!GO:0003756;protein disulfide isomerase activity;0.0133250808496145!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0133250808496145!GO:0000139;Golgi membrane;0.0133424649753084!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0134133979073111!GO:0045045;secretory pathway;0.0136785246719286!GO:0016584;nucleosome positioning;0.0137098332152557!GO:0007040;lysosome organization and biogenesis;0.0139745910282583!GO:0008637;apoptotic mitochondrial changes;0.0140250730314851!GO:0030145;manganese ion binding;0.0140361266015218!GO:0046983;protein dimerization activity;0.0140361266015218!GO:0016407;acetyltransferase activity;0.0140542439290249!GO:0007021;tubulin folding;0.0142071624258565!GO:0006695;cholesterol biosynthetic process;0.0142343151274304!GO:0030658;transport vesicle membrane;0.0142684407096629!GO:0043189;H4/H2A histone acetyltransferase complex;0.0144587454329204!GO:0035267;NuA4 histone acetyltransferase complex;0.0147172262466182!GO:0046822;regulation of nucleocytoplasmic transport;0.0148668094458756!GO:0030134;ER to Golgi transport vesicle;0.0149056989786822!GO:0022411;cellular component disassembly;0.0152785596027887!GO:0006497;protein amino acid lipidation;0.0152951467256802!GO:0006672;ceramide metabolic process;0.0155283802203564!GO:0006376;mRNA splice site selection;0.0156375013866472!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0156375013866472!GO:0006607;NLS-bearing substrate import into nucleus;0.0156375013866472!GO:0018193;peptidyl-amino acid modification;0.0157867342285811!GO:0016126;sterol biosynthetic process;0.0158925317691816!GO:0006505;GPI anchor metabolic process;0.016052520259322!GO:0016044;membrane organization and biogenesis;0.0161563282313167!GO:0046966;thyroid hormone receptor binding;0.0161563282313167!GO:0031570;DNA integrity checkpoint;0.016193337967322!GO:0032039;integrator complex;0.0162450899556096!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0171227858745208!GO:0046112;nucleobase biosynthetic process;0.0175480594114576!GO:0003746;translation elongation factor activity;0.0176073744924053!GO:0016860;intramolecular oxidoreductase activity;0.0176341460944804!GO:0000725;recombinational repair;0.0178435391270234!GO:0000724;double-strand break repair via homologous recombination;0.0178435391270234!GO:0048471;perinuclear region of cytoplasm;0.0180606720613352!GO:0009161;ribonucleoside monophosphate metabolic process;0.018296679367368!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.018296679367368!GO:0033673;negative regulation of kinase activity;0.018363566410284!GO:0006469;negative regulation of protein kinase activity;0.018363566410284!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0186644793273034!GO:0016605;PML body;0.0186868674009856!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0187208396209912!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0187266267087687!GO:0019318;hexose metabolic process;0.0188471699903044!GO:0000726;non-recombinational repair;0.0190695621355938!GO:0005996;monosaccharide metabolic process;0.0194589357622071!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.0196617877873704!GO:0000123;histone acetyltransferase complex;0.0197219760836792!GO:0051348;negative regulation of transferase activity;0.0199601470037872!GO:0005869;dynactin complex;0.0199601470037872!GO:0006007;glucose catabolic process;0.0201224062080697!GO:0048037;cofactor binding;0.0203871611703993!GO:0000118;histone deacetylase complex;0.0204476226941859!GO:0043241;protein complex disassembly;0.0205521319724201!GO:0045449;regulation of transcription;0.0209472640512919!GO:0006979;response to oxidative stress;0.0209919670936565!GO:0040029;regulation of gene expression, epigenetic;0.0210822800548675!GO:0016408;C-acyltransferase activity;0.0211152735395754!GO:0030137;COPI-coated vesicle;0.0212223316748023!GO:0043596;nuclear replication fork;0.0216232085553536!GO:0030127;COPII vesicle coat;0.0216620236428732!GO:0012507;ER to Golgi transport vesicle membrane;0.0216620236428732!GO:0006733;oxidoreduction coenzyme metabolic process;0.0222318271486464!GO:0008320;protein transmembrane transporter activity;0.0228822970374709!GO:0007033;vacuole organization and biogenesis;0.0229090135818778!GO:0000097;sulfur amino acid biosynthetic process;0.0229726759695233!GO:0050178;phenylpyruvate tautomerase activity;0.0233424277474174!GO:0051053;negative regulation of DNA metabolic process;0.0239279306641288!GO:0007017;microtubule-based process;0.0239279306641288!GO:0008213;protein amino acid alkylation;0.0239279306641288!GO:0006479;protein amino acid methylation;0.0239279306641288!GO:0008180;signalosome;0.0239678847598914!GO:0016791;phosphoric monoester hydrolase activity;0.0239678847598914!GO:0008629;induction of apoptosis by intracellular signals;0.0241655115391267!GO:0006118;electron transport;0.0241655115391267!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.024502056181453!GO:0000819;sister chromatid segregation;0.0245276132487245!GO:0003887;DNA-directed DNA polymerase activity;0.0245681324407854!GO:0030660;Golgi-associated vesicle membrane;0.0246187601054837!GO:0060090;molecular adaptor activity;0.0247000237488433!GO:0007004;telomere maintenance via telomerase;0.0248407240452752!GO:0046426;negative regulation of JAK-STAT cascade;0.025300380695465!GO:0042770;DNA damage response, signal transduction;0.0256632530000409!GO:0000228;nuclear chromosome;0.0263321267814303!GO:0030132;clathrin coat of coated pit;0.0266334534079184!GO:0003702;RNA polymerase II transcription factor activity;0.0272252219072072!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0281767047092446!GO:0008538;proteasome activator activity;0.0282607797202686!GO:0000781;chromosome, telomeric region;0.0284176893276937!GO:0006596;polyamine biosynthetic process;0.0284837224024051!GO:0009083;branched chain family amino acid catabolic process;0.028498350804659!GO:0000152;nuclear ubiquitin ligase complex;0.0287529873909893!GO:0005744;mitochondrial inner membrane presequence translocase complex;0.0287762031441748!GO:0031371;ubiquitin conjugating enzyme complex;0.0287974871286359!GO:0005874;microtubule;0.0287974871286359!GO:0005652;nuclear lamina;0.0287974871286359!GO:0046365;monosaccharide catabolic process;0.0287974871286359!GO:0043624;cellular protein complex disassembly;0.0287974871286359!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.0287974871286359!GO:0033367;protein localization in mast cell secretory granule;0.0287974871286359!GO:0033365;protein localization in organelle;0.0287974871286359!GO:0033371;T cell secretory granule organization and biogenesis;0.0287974871286359!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.0287974871286359!GO:0033375;protease localization in T cell secretory granule;0.0287974871286359!GO:0042629;mast cell granule;0.0287974871286359!GO:0033377;maintenance of protein localization in T cell secretory granule;0.0287974871286359!GO:0033364;mast cell secretory granule organization and biogenesis;0.0287974871286359!GO:0033380;granzyme B localization in T cell secretory granule;0.0287974871286359!GO:0033379;maintenance of protease localization in T cell secretory granule;0.0287974871286359!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.0287974871286359!GO:0033368;protease localization in mast cell secretory granule;0.0287974871286359!GO:0033366;protein localization in secretory granule;0.0287974871286359!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.0287974871286359!GO:0033374;protein localization in T cell secretory granule;0.0287974871286359!GO:0016197;endosome transport;0.0288403471528156!GO:0007259;JAK-STAT cascade;0.0292113061448291!GO:0000070;mitotic sister chromatid segregation;0.0294410500601618!GO:0030984;kininogen binding;0.029602274045713!GO:0004213;cathepsin B activity;0.029602274045713!GO:0005096;GTPase activator activity;0.0308389971080286!GO:0031577;spindle checkpoint;0.0308389971080286!GO:0030508;thiol-disulfide exchange intermediate activity;0.0311713508388292!GO:0030433;ER-associated protein catabolic process;0.0314132215047252!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0314132215047252!GO:0019206;nucleoside kinase activity;0.0318128944467744!GO:0051235;maintenance of localization;0.0319803922190294!GO:0005784;translocon complex;0.0329219341445335!GO:0004540;ribonuclease activity;0.033027939849336!GO:0008415;acyltransferase activity;0.0331655376016396!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0332125431298432!GO:0000175;3'-5'-exoribonuclease activity;0.0340975083870369!GO:0008017;microtubule binding;0.0340985197610843!GO:0008170;N-methyltransferase activity;0.0341006818829131!GO:0006360;transcription from RNA polymerase I promoter;0.034815304479153!GO:0048518;positive regulation of biological process;0.0351088212569524!GO:0042158;lipoprotein biosynthetic process;0.0353012854867889!GO:0000910;cytokinesis;0.0353944385677027!GO:0050681;androgen receptor binding;0.0354439282306949!GO:0008652;amino acid biosynthetic process;0.0356759277071435!GO:0006470;protein amino acid dephosphorylation;0.0356862325367894!GO:0016747;transferase activity, transferring groups other than amino-acyl groups;0.0359498653125431!GO:0032940;secretion by cell;0.0371001106874148!GO:0006400;tRNA modification;0.0374506977236002!GO:0000159;protein phosphatase type 2A complex;0.0377423398349758!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0378538748009088!GO:0000077;DNA damage checkpoint;0.0379448152988031!GO:0005092;GDP-dissociation inhibitor activity;0.0380051333854095!GO:0004748;ribonucleoside-diphosphate reductase activity;0.038192918346347!GO:0016728;oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor;0.038192918346347!GO:0009119;ribonucleoside metabolic process;0.0382073052520511!GO:0032981;mitochondrial respiratory chain complex I assembly;0.038221058531576!GO:0010257;NADH dehydrogenase complex assembly;0.038221058531576!GO:0033108;mitochondrial respiratory chain complex assembly;0.038221058531576!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.038524722139712!GO:0045039;protein import into mitochondrial inner membrane;0.038524722139712!GO:0045947;negative regulation of translational initiation;0.0391594658907577!GO:0031625;ubiquitin protein ligase binding;0.0400714937729635!GO:0051098;regulation of binding;0.0402820129472354!GO:0008097;5S rRNA binding;0.0404455273233554!GO:0006779;porphyrin biosynthetic process;0.0409009366625756!GO:0033014;tetrapyrrole biosynthetic process;0.0409009366625756!GO:0006739;NADP metabolic process;0.0409009366625756!GO:0031902;late endosome membrane;0.0412546611059789!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0413867112406514!GO:0006278;RNA-dependent DNA replication;0.0415182645451101!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0419564369701388!GO:0009396;folic acid and derivative biosynthetic process;0.0419564369701388!GO:0030911;TPR domain binding;0.0422467208846066!GO:0016180;snRNA processing;0.0422467208846066!GO:0016073;snRNA metabolic process;0.0422467208846066!GO:0016746;transferase activity, transferring acyl groups;0.0422467208846066!GO:0046164;alcohol catabolic process;0.0423486865290664!GO:0008022;protein C-terminus binding;0.0427951070501542!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.0429054921654427!GO:0009127;purine nucleoside monophosphate biosynthetic process;0.0430658856398586!GO:0009167;purine ribonucleoside monophosphate metabolic process;0.0430658856398586!GO:0009126;purine nucleoside monophosphate metabolic process;0.0430658856398586!GO:0009168;purine ribonucleoside monophosphate biosynthetic process;0.0430658856398586!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0433103927296646!GO:0022884;macromolecule transmembrane transporter activity;0.0433984393540855!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.0433984393540855!GO:0030133;transport vesicle;0.0433984393540855!GO:0019320;hexose catabolic process;0.0435222842591067!GO:0042532;negative regulation of tyrosine phosphorylation of STAT protein;0.0437138703389199!GO:0042518;negative regulation of tyrosine phosphorylation of Stat3 protein;0.0437138703389199!GO:0050732;negative regulation of peptidyl-tyrosine phosphorylation;0.0437138703389199!GO:0006892;post-Golgi vesicle-mediated transport;0.0443764983482544!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.0450983639731865!GO:0008601;protein phosphatase type 2A regulator activity;0.045181881685186!GO:0032507;maintenance of cellular protein localization;0.0452186331078588!GO:0015923;mannosidase activity;0.0465179349775416!GO:0000303;response to superoxide;0.0467542566814674!GO:0008536;Ran GTPase binding;0.0471756975013153!GO:0000790;nuclear chromatin;0.0472170153770386!GO:0045815;positive regulation of gene expression, epigenetic;0.0472289120299338!GO:0005975;carbohydrate metabolic process;0.0474857348597004!GO:0008361;regulation of cell size;0.0475490525155757!GO:0000209;protein polyubiquitination;0.0484919724867038!GO:0005666;DNA-directed RNA polymerase III complex;0.0486500882611047!GO:0004448;isocitrate dehydrogenase activity;0.0488153829003689!GO:0046588;negative regulation of calcium-dependent cell-cell adhesion;0.0493257054221554!GO:0046586;regulation of calcium-dependent cell-cell adhesion;0.0493257054221554!GO:0008624;induction of apoptosis by extracellular signals;0.0497175656806267!GO:0006406;mRNA export from nucleus;0.0498686484874706
|sample_id=10801
|sample_note=
|sample_sex=female
|sample_species=Human (Homo sapiens)
|sample_strain=
|sample_tissue=blood
|top_motifs=RXR{A,B,G}_{NR1H2,PPAR}dimers:1.82251741506;ALX1:1.60046636006;MYB:1.51014496864;GATA6:1.43803514315;POU3F1..4:1.28503625799;RUNX1..3:1.213120772;E2F1..5:1.21270208545;ELF1,2,4:1.16621426064;FOX{I1,J2}:1.15370540865;ZBTB16:1.12347628545;NANOG{mouse}:0.9711915973;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.966690243268;NR5A1,2:0.89284687112;YY1:0.863561841387;PITX1..3:0.860690574659;DMAP1_NCOR{1,2}_SMARC:0.850816457601;POU2F1..3:0.816732653207;SPIB:0.77378353677;TEF:0.734746148279;AIRE:0.722730542083;HES1:0.721295822781;ZNF143:0.698637444873;ETS1,2:0.615351258622;HIF1A:0.592431969204;AR:0.570063825336;SPI1:0.563996537351;NFY{A,B,C}:0.543808010815;FOXP1:0.538830977117;NKX3-1:0.536056065364;IKZF2:0.530129460393;ELK1,4_GABP{A,B1}:0.522952470666;CUX2:0.453742475924;bHLH_family:0.43367396961;CREB1:0.400400532791;FOXD3:0.397752213684;BREu{core}:0.391219678878;NKX2-1,4:0.376380344731;CDX1,2,4:0.371909629664;TOPORS:0.334131636326;PRRX1,2:0.332742614445;POU1F1:0.330770842885;PAX6:0.323813378461;NRF1:0.32318119253;FOXQ1:0.277955507292;STAT1,3:0.277833929788;GCM1,2:0.26778530128;SOX17:0.257731071984;NKX2-3_NKX2-5:0.255499404095;PBX1:0.25201174212;PPARG:0.245287436818;FOXP3:0.228221739608;STAT5{A,B}:0.220984368216;GATA4:0.172592864189;PAX2:0.141444977409;PAX8:0.137724851541;DBP:0.12018232416;NKX2-2,8:0.0919340980318;NFIL3:0.0902555244316;FOXN1:0.0895532984825;ARID5B:0.0816344714589;HAND1,2:0.0603174581204;ONECUT1,2:0.0462368444714;HOXA9_MEIS1:0.0382713105365;MYOD1:0.0337364461919;SOX{8,9,10}:0.0101509197323;CRX:-0.00391005044479;HOX{A4,D4}:-0.022012680457;PAX3,7:-0.0427272595286;NFE2L1:-0.0598213806858;ATF5_CREB3:-0.0615839026237;RORA:-0.0803613540933;HBP1_HMGB_SSRP1_UBTF:-0.0908567417381;HNF1A:-0.0997422439477;PDX1:-0.101734363276;TFAP4:-0.103722224939;HNF4A_NR2F1,2:-0.106563930207;AHR_ARNT_ARNT2:-0.110251915713;NFATC1..3:-0.121807631722;EVI1:-0.131043571233;ZNF384:-0.138701070062;VSX1,2:-0.140139691502;RBPJ:-0.152868927786;RFX2..5_RFXANK_RFXAP:-0.157059223126;NFE2L2:-0.159671516247;EP300:-0.160159258928;NR6A1:-0.172371084788;POU6F1:-0.177303477776;ESRRA:-0.181618864913;RXR{A,B,G}:-0.182677756012;ZIC1..3:-0.187397279154;REST:-0.189613781293;ZNF423:-0.202408318313;PAX1,9:-0.20291396558;MEF2{A,B,C,D}:-0.204399140993;STAT2,4,6:-0.215907128487;XBP1:-0.221466436297;TFDP1:-0.226765638858;HIC1:-0.230755132874;EN1,2:-0.235537151711;OCT4_SOX2{dimer}:-0.239204558564;LHX3,4:-0.245197704973;FOXA2:-0.252041569267;NFE2:-0.261906367665;NKX6-1,2:-0.272474057484;NANOG:-0.278122872767;TLX2:-0.288280215231;LEF1_TCF7_TCF7L1,2:-0.306300598808;ZNF238:-0.307954507353;ZNF148:-0.324099356463;PRDM1:-0.334894264269;FOX{F1,F2,J1}:-0.342571104643;BACH2:-0.347379075933;CEBPA,B_DDIT3:-0.351479246087;NFKB1_REL_RELA:-0.35782869466;ZFP161:-0.386486896318;PAX5:-0.397311326406;MYBL2:-0.397645094876;FOS_FOS{B,L1}_JUN{B,D}:-0.413240179849;HOX{A5,B5}:-0.432326807757;SNAI1..3:-0.454131774082;RREB1:-0.454909435578;SRF:-0.48264364189;SOX2:-0.49245714354;IRF1,2:-0.515505873305;UFEwm:-0.516729819273;ESR1:-0.522356656917;ATF4:-0.530387331267;KLF4:-0.532666472161;ZEB1:-0.535864704517;PAX4:-0.554237778102;POU5F1:-0.564997746952;MTF1:-0.574423640037;HLF:-0.602330331494;TGIF1:-0.611049812653;FOSL2:-0.617941820386;TAL1_TCF{3,4,12}:-0.62457168657;NHLH1,2:-0.628158392045;RXRA_VDR{dimer}:-0.633356090203;EGR1..3:-0.636845038752;SOX5:-0.638218159445;MZF1:-0.645810159016;TBP:-0.655876705993;GTF2A1,2:-0.660220663225;EBF1:-0.664419812861;TFAP2B:-0.671757277043;FOXM1:-0.690317886884;MYFfamily:-0.692204577524;SMAD1..7,9:-0.701281053061;IKZF1:-0.702550177049;HOX{A6,A7,B6,B7}:-0.707840175875;ZBTB6:-0.716885654245;ALX4:-0.72618240043;GLI1..3:-0.729999151786;GTF2I:-0.734200933851;BPTF:-0.736894653883;RFX1:-0.753023977136;SREBF1,2:-0.767400270442;GFI1:-0.770944631481;ATF6:-0.79910706202;XCPE1{core}:-0.818890445892;FOXL1:-0.819384273494;HMGA1,2:-0.819854195907;CDC5L:-0.825588256869;IRF7:-0.842641904338;GZF1:-0.84465591674;NKX3-2:-0.851717157953;PATZ1:-0.913572050871;MED-1{core}:-0.933091844688;SP1:-0.933177078332;TFAP2{A,C}:-0.934960090768;TEAD1:-0.940771069636;FOXO1,3,4:-0.993288645396;HMX1:-0.99676301474;HSF1,2:-1.01557322137;T:-1.01820601853;MAZ:-1.03692846654;FOX{D1,D2}:-1.05657447464;TP53:-1.07590686961;MTE{core}:-1.08449087795;TLX1..3_NFIC{dimer}:-1.10982025127;JUN:-1.13761981831;SPZ1:-1.18209274696;LMO2:-1.22103563472;ATF2:-1.26064109372;ADNP_IRX_SIX_ZHX:-1.44259635166;TBX4,5:-1.4993766992;NFIX:-1.52252587581;GFI1B:-1.64015411173;MAFB:-1.65717290087;NR3C1:-1.67203595255;TFCP2:-1.68455065825;NR1H4:-1.72050204635
|xref=
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10801-110I9;search_select_hide=table117:FF:10801-110I9
}}
}}

Latest revision as of 15:05, 3 June 2020

Name:chronic myeloblastic leukemia (CML) cell line:KCL-22
Species:Human (Homo sapiens)
Library ID:CNhs11886
Sample type:cell lines
Genomic View: UCSC
RefEX:Specific genes
CAGEd-oPOSSUM:link
ZENBU report :link
Additional information
Sample information
strainNA
tissueblood
dev stageNA
sexfemale
age28
cell typegranulocyte monocyte progenitor cell
cell lineKCL-22
companyJAPAN HEALTH SCIENCES FOUNDATION - Health Science Research Resources Bank
collaborationFANTOM5 OSC CORE (contact: Al Forrest)
External link for information[{{{sample_info_link}}} {{{sample_info_link}}}]
RNA information
lot numberNA
catalog numberNA
sample typetotal RNA
extraction protocol (Details)OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0

CAGE Accession numbers
MethodSample accession id
CAGE  SAMD00005470
Library accession numbers

Library idMethodExp. accession idRun accession id
CNhs11886 CAGE DRX007853 DRR008725
Accession ID Hg19

Library idBAMCTSS
CNhs11886 DRZ000150 DRZ001535
Accession ID Hg38

Library idBAMCTSS
CNhs11886 DRZ011500 DRZ012885
Download raw sequence, BAM & CTSS
Hg19
FastaBAMCTSS
downloaddownloaddonwload
Hg38
BAMCTSS
downloaddonwload


Relative expression to median (log10)


Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.



Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data

Coexpression clusterscore
C0-CD14-Eosinophils-Neutrophils-Basophils-CD34-immature-Peripheral0
C1-testis-epididymis-embryonic-medulla-pituitary-trachea-caudate0
C10-occipital-temporal-parietal-brain-duodenum-Neurons-Neural0
C100-rhabdomyosarcoma-gastric-pineal-Wilms-cervical-mesodermal-endometrial0
C101-small-cerebellum-maxillary-colon-parietal-epididymis-merkel0
C102-neuroblastoma-testicular-pituitary-carcinosarcoma-rectum-acantholytic-iPS0
C103-CD4-CD8-Natural-Peripheral-Whole-Neutrophils-Basophils0
C104-Mast-Basophils-immature-CD14-CD34-eye-Natural0
C105-heart-skeletal-occipital-hippocampus-acute-Sebocyte-penis0.147
C106-Hep2-epitheloid-placenta-cervical-rectal-anaplastic-glassy0
C107-Neutrophils-CD14-Eosinophils-Monocytederived-Whole-Peripheral-blood0
C108-breast-hepatoblastoma-MCF7-parotid-salivary-submaxillary-prostate0
C109-Reticulocytes-non-acute-Hodgkin-Burkitt-retinoblastoma-lymphoma0.481
C11-cerebellum-medulla-pons-parietal-occipital-middle-medial0
C110-leukemia-chronic-Eosinophils-acute-Whole-CD34-Lymphatic0
C111-medulla-lung-trachea-testis-caudate-epididymis-throat0
C112-gastric-pancreas-temporal-duodenum-small-extraskeletal-adrenal0
C113-thyroid-throat-lung-lymph-small-colon-trachea0
C114-teratocarcinoma-medulloblastoma-carcinosarcoma-iPS-anaplastic-acute-neuroblastoma0
C115-pituitary-Neural-caudate-putamen-amygdala-medulla-hippocampus0
C116-myeloma-xeroderma-tonsil-CD19-spleen-lymph-trachea0
C117-serous-clear-kidney-neuroectodermal-mesothelioma-endometrial-Intestinal0
C118-cerebellum-parietal-occipital-medial-middle-frontal-insula0
C119-CD4-CD8-Natural-Neutrophils-CD14-Peripheral-CD190
C12-Mast-Basophils-immature-chorionic-mature-CD14-Eosinophils0
C120-immature-salivary-tongue-skin-cervical-CD14-CD340
C121-NK-Natural-CD8-CD4-anaplastic-chronic-B0
C122-chronic-Reticulocytes-skeletal-leukemia-acute-colon-Tracheal0
C123-CD19-Natural-CD8-CD4-CD14-Peripheral-Basophils0
C124-small-temporal-duodenum-colon-gall-signet-Hepatocyte0
C125-mucinous-alveolar-mesothelioma-Smooth-lung-CD14-Nucleus0
C126-gastrointestinal-argyrophil-smallcell-merkel-bile-insula-brain0
C127-maxillary-small-hepatoblastoma-hepatocellular-alveolar-colon-argyrophil0
C128-testicular-choriocarcinoma-H9-teratocarcinoma-pancreatic-iPS-HES3GFP0
C129-liver-Hepatocyte-colon-duodenum-temporal-testicular-small0
C13-Neutrophils-Eosinophils-CD14-Monocytederived-Whole-Peripheral-CD40
C130-iPS-HES3GFP-H9-teratocarcinoma-testicular-colon-Alveolar0
C131-lung-trachea-Alveolar-thyroid-umbilical-throat-skin0
C132-acute-small-Dendritic-Macrophage-CD14-Neutrophils-Monocytederived0
C133-signet-gall-small-kidney-colon-ductal-adenocarcinoma0
C134-skeletal-diaphragm-tongue-throat-Skeletal-skin-penis0
C135-neuroblastoma-retinoblastoma-carcinoid-choriocarcinoma-testicular-acute-rectum0
C136-Wilms-extraskeletal-anaplastic-rhabdomyosarcoma-cholangiocellular-nonsmall-neuroectodermal0
C137-large-ductal-melanoma-cervical-Endothelial-Smooth-chronic0
C138-diffuse-Burkitt-lymphangiectasia-lymphoma-acute-CD19-pineal0
C139-astrocytoma-skin-salivary-gall-serous-Mallassezderived-renal0
C14-Whole-blood-Reticulocytes-liver-Neutrophils-Eosinophils-spleen0
C140-Renal-Endothelial-Hepatic-Lymphatic-heart-lung-spleen0
C141-Hodgkin-acute-thymus-chronic-vein-CD4-B0
C142-Preadipocyte-Fibroblast-hepatic-Ewing-Adipocyte-Olfactory-Hair0
C143-Monocytederived-CD14-Macrophage-Dendritic-Basophils-CD14CD16-Osteoblast0
C144-CD4-tonsil-NK-appendix-CD8-splenic-mycosis0
C145-neuroblastoma-peripheral-neuroectodermal-neuroepithelioma-carcinoid-adult-extraskeletal0
C146-lymphangiectasia-lymphoma-gall-lymph-tonsil-gastric-transitionalcell0
C147-Neutrophils-Eosinophils-CD4-CD14-CD8-Natural-Peripheral0
C148-kidney-small-epididymis-pancreas-serous-duodenum-temporal0
C149-occipital-medial-brain-amygdala-parietal-cerebral-cerebellum0
C15-anaplastic-small-skeletal-neuroblastoma-parietal-temporal-tongue0
C150-merkel-carcinoid-nonsmall-gastrointestinal-argyrophil-pineal-small0
C151-CD14-Natural-Basophils-CD8-Eosinophils-CD4-Mast0
C152-peripheral-neuroectodermal-neuroepithelioma-neuroblastoma-testicular-carcinoid-lung0
C153-rhabdomyosarcoma-liposarcoma-pancreatic-somatostatinoma-Reticulocytes-lymphoma-testicular0
C154-adenocarcinoma-Mesenchymal-Cardiac-small-sacrococcigeal-Smooth-Prostate0
C155-pituitary-placenta-nonsmall-cervical-smallcell-choriocarcinoma-epitheloid0
C156-plasma-splenic-hereditary-B-large-xeroderma-b0
C157-testicular-H9-testis-iPS-teratocarcinoma-colon-trachea0
C158-adrenal-gastric-temporal-parietal-duodenum-caudate-putamen0
C159-choriocarcinoma-pancreatic-placenta-chorionic-testicular-bronchioalveolar-seminal0
C16-medial-amygdala-occipital-parietal-olfactory-putamen-brain0
C160-medulla-Hepatocyte-retina-corpus-liver-pineal-cerebral0
C161-mesothelioma-Mesothelial-acute-mesenchymal-extraskeletal-renal-placenta0
C162-spinal-locus-medulla-substantia-thalamus-globus-diencephalon0
C163-Skeletal-skeletal-Pericytes-Hepatic-rhabdomyosarcoma-throat-mesenchymal0
C164-signet-corpus-optic-mucinous-substantia-salivary-choriocarcinoma0
C165-epithelioid-Adipocyte-mesothelioma-myxofibrosarcoma-lung-gastric-Mesothelial0
C166-Macrophage-Monocytederived-Dendritic-adipose-lymph-CD14-lung0
C167-Basophils-Mast-Eosinophils-Neutrophils-Peripheral-Whole-CD40
C168-Mast-CD14-immature-Basophils-Eosinophils-CD34-Peripheral0
C169-hereditary-adult-gall-lymphangiectasia-chronic-b-choriocarcinoma0
C17-Mast-CD14-Monocytederived-Lymphatic-Smooth-mesenchymal-Macrophage0
C170-epitheloid-cervical-Hep2-keratoacanthoma-adult-neuroblastoma-signet0
C171-merkel-neuroblastoma-pineal-retinoblastoma-carcinoid-small-eye0
C172-chorionic-skeletal-tongue-amniotic-liver-gastrointestinal-Pericytes0
C173-Adipocyte-mature-skin-left-Hepatocyte-Osteoblast-adipose0
C174-CD14-Neutrophils-Smooth-mesothelioma-embryonic-Monocytederived-Eosinophils0
C175-Eosinophils-Neutrophils-CD4-Basophils-CD19-CD8-Natural0
C176-Eosinophils-Neutrophils-Mast-CD14-CD4-Basophils-CD19-0.0391
C177-melanoma-Melanocyte-mesenchymal-retina-Mallassezderived-Gingival-squamous0
C178-spleen-liver-Hepatocyte-b-lymph-vein-thymus0
C179-CD19-Peripheral-lymphoma-blood-lymph-spleen-tonsil0
C18-CD4-CD8-thymus-Whole-Peripheral-Natural-blood0
C180-skeletal-heart-Hepatocyte-acute-occipital-hippocampus-middle-0.0551
C181-liposarcoma-somatostatinoma-neuroblastoma-mesothelioma-nonsmall-small-Alveolar0
C182-renal-mature-mesothelioma-lung-Mammary-Adipocyte-acute0
C183-acute-non-CD34-diffuse-CD133-myeloma-Burkitt0
C184-somatostatinoma-smallcell-nonsmall-small-gastrointestinal-pineal-thyroid0
C185-small-adrenal-gastric-Mesenchymal-acute-HES3GFP-testis0
C186-squamous-papillotubular-large-Tracheal-oral-Small-epidermoid0
C187-migratory-immature-Dendritic-CD19-CD14-Monocytederived-Macrophage0
C188-left-heart-tongue-skeletal-Skeletal-diaphragm-throat0
C189-b-splenic-tonsil-CD19-lymph-appendix-spleen0
C19-embryonic-testis-cord-chronic-CD14-NK-mesothelioma0
C190-colon-small-rectum-duodenum-appendix-temporal-oral0
C191-leiomyoblastoma-Mast-parietal-acute-bone-neuroepithelioma-embryonic0
C192-Neutrophils-CD14-Peripheral-Eosinophils-CD8-Natural-CD40
C193-Mesenchymal-Adipocyte-mature-Cardiac-heart-CD14CD16-CD140
C194-MCF7-breast-prostate-Intestinal-diffuse-Wilms-Alveolar0
C195-Small-Gingival-Bronchial-Smooth-mesenchymal-Urothelial-Tracheal0
C196-testicular-iPS-H9-teratocarcinoma-HES3GFP-choriocarcinoma-endometrial0
C197-tongue-esophagus-tonsil-salivary-cervix-nasal-Gingival0
C198-Mesenchymal-Hair-Hepatic-Fibroblast-Smooth-tenocyte-Pericytes0
C199-glioblastoma-B-osteosarcoma-Fibroblast-heart-rhabdomyosarcoma-myxofibrosarcoma0
C2-Eosinophils-Neutrophils-CD14-Whole-Basophils-Peripheral-Mast0
C20-heart-left-skeletal-diaphragm-tongue-umbilical-throat0
C200-seminal-Cardiac-Smooth-Hair-submaxillary-Neutrophils-mixed-0.0862
C201-colon-small-adenocarcinoma-duodenum-temporal-signet-gall0
C202-salivary-skin-penis-tongue-uterus-cervical-immature0
C203-acute-NK-chronic-CD133-lymphoma-immature-Dendritic0
C204-Smooth-nasal-CD4-CD19-CD8-CD14-CD340
C205-mycosis-cord-hairy-xeroderma-CD4-B-b0
C206-melanoma-somatostatinoma-nonsmall-small-neuroblastoma-smallcell-pituitary0
C207-Corneal-Keratinocyte-Esophageal-Mammary-Bronchial-Urothelial-Sebocyte0
C208-skin-amniotic-papillotubular-salivary-umbilical-Alveolar-serous0
C209-acute-myelodysplastic-CD34-granulocyte-CD133-liver-spleen0
C21-cord-mycosis-hairy-xeroderma-adult-CD4-anaplastic0
C210-Burkitt-lymphoma-appendix-acute-diffuse-CD19-tonsil0
C211-small-Hepatocyte-liver-colon-temporal-duodenum-kidney0
C212-chronic-acute-Whole-Reticulocytes-leukemia-blood-CD340
C213-CD14-Natural-CD8-CD4-Basophils-Eosinophils-Peripheral0
C214-Neurons-Neural-duodenum-temporal-occipital-parietal-brain0
C215-chronic-acute-peripheral-Hepatocyte-osteosarcoma-NK-immature0.991
C216-osteosarcoma-Smooth-Mesenchymal-large-neuroectodermal-acute-CD340
C217-carcinoid-neuroectodermal-mature-mesodermal-colon-acute-occipital0
C218-tonsil-lymph-CD19-spleen-colon-appendix-salivary0
C219-nasal-Basophils-amniotic-Melanocyte-CD14-Osteoblast-duodenum0
C22-CD4-CD8-Natural-Basophils-CD14-Peripheral-CD190
C220-Adipocyte-mature-left-breast-skin-liver-adipose0
C221-alveolar-Osteoblast-Myoblast-mesenchymal-liposarcoma-Smooth-hepatocellular0
C222-Melanocyte-Tracheal-Neutrophils-seminal-Smooth-Hair-Chondrocyte-0.0266
C223-Chondrocyte-basal-renal-Fibroblast-Smooth-spindle-Synoviocyte0
C224-clear-serous-pleomorphic-choriocarcinoma-mesothelioma-amniotic-renal0
C225-ductal-alveolar-giant-prostate-salivary-squamous-Tracheal0
C226-Corneal-Keratinocyte-Esophageal-Urothelial-Mammary-Bronchial-Tracheal0
C227-chorionic-amniotic-Mesenchymal-Placental-gastric-diaphragm-tongue0
C228-colon-Intestinal-Prostate-hepatoblastoma-hepatocellular-testis-adult0
C229-Mesenchymal-CD4-Melanocyte-acute-skeletal-left-heart0.0633
C23-CD4-CD8-Natural-Peripheral-Basophils-CD19-CD140
C230-aorta-normal-heart-penis-osteosarcoma-basal-lung0
C231-Mesothelial-mesenchymal-mesothelioma-Fibroblast-Preadipocyte-leiomyoma-mycosis0
C232-teratocarcinoma-HES3GFP-H9-iPS-testicular-neuroblastoma-cerebellum0
C233-uterus-cervix-ovary-epididymis-colon-rectum-MCF70
C234-oral-epidermoid-malignant-cervical-ductal-lung-keratoacanthoma0
C235-Intestinal-Prostate-liver-colon-small-kidney-pancreas0
C236-CD14-Neutrophils-Monocytederived-renal-Eosinophils-testis-mesothelioma0
C237-acute-breast-testicular-hepatoblastoma-chronic-argyrophil-Bronchial0
C238-stomach-gall-breast-duodenum-temporal-MCF7-smallcell0
C239-CD4-lymphangiectasia-CD8-NK-mycosis-Renal-hairy0
C24-pineal-eye-retina-retinoblastoma-medulloblastoma-small-cerebral0
C240-Adipocyte-Preadipocyte-Osteoblast-Chondrocyte-tenocyte-Synoviocyte-mesenchymal0
C241-Reticulocytes-chronic-Tracheal-Hodgkin-Endothelial-Hair-thymus0.552
C242-acute-Chondrocyte-myelodysplastic-granulocyte-biphenotypic-Fibroblast-stomach0
C243-Chondrocyte-trachea-Synoviocyte-mesodermal-renal-Fibroblast-Ewing0
C244-CD14-Monocytederived-Hepatocyte-heart-Neutrophils-acute-Macrophage0
C245-prostate-penis-salivary-esophagus-kidney-Neutrophils-Pancreatic0
C246-Neutrophils-Eosinophils-Whole-CD14-CD14CD16-Basophils-migratory0.283
C247-pons-locus-medulla-spinal-paracentral-medial-occipital0
C248-iPS-Aortic-Hep2-amygdala-acute-medial-Myoblast0
C249-nonsmall-small-smallcell-occipital-somatostatinoma-maxillary-medial0
C25-small-colon-temporal-duodenum-liver-Hepatocyte-gall0
C250-Mast-Neutrophils-CD14-Eosinophils-CD8-Peripheral-CD40
C251-gall-tonsil-trachea-CD14-salivary-throat-tongue0
C252-hepatic-Olfactory-sacrococcigeal-leiomyoma-normal-Synoviocyte-glioblastoma0
C253-spleen-rhabdomyosarcoma-Hepatocyte-small-uterus-liver-rectum0
C254-prostate-rhabdomyosarcoma-seminal-Fibroblast-transitionalcell-Smooth-Iris0
C255-Wilms-leiomyoblastoma-kidney-adrenal-MCF7-epithelioid-Mast0
C256-occipital-caudate-amygdala-medial-thalamus-hippocampus-medulla0
C257-pineal-insula-frontal-occipital-temporal-medial-paracentral0
C258-hepatoblastoma-hepatocellular-signet-colon-Intestinal-Prostate-gastric0
C259-Preadipocyte-Adipocyte-Fibroblast-Chondrocyte-tenocyte-normal-Ewing0
C26-Eosinophils-Neutrophils-CD14-CD14CD16-Basophils-Monocytederived-Whole0
C260-acute-chronic-Natural-NK-Basophils-biphenotypic-blood0
C261-locus-medial-parietal-pons-diencephalon-olfactory-spinal0
C262-breast-MCF7-skeletal-Reticulocytes-mucinous-hepatoblastoma-Wilms0
C263-cervical-keratoacanthoma-tongue-skin-esophagus-throat-tonsil0
C264-giant-keratoacanthoma-colon-fibrosarcoma-HES3GFP-Hep2-acute0
C265-CD4-Eosinophils-CD14-Natural-CD19-Basophils-CD80
C266-acute-chronic-leukemia-small-choriocarcinoma-hepatoma-Mast0
C267-pancreatic-placenta-choriocarcinoma-testicular-teratocarcinoma-chorionic-clear0
C268-Mallassezderived-Urothelial-Gingival-Small-Bronchial-Tracheal-Prostate0
C269-Basophils-Mast-Eosinophils-mature-CD14-chorionic-CD40
C27-pancreas-temporal-duodenum-salivary-ductus-umbilical-lung0
C270-CD4-Fibroblast-acute-iPS-Aortic-CD34-Smooth0.0159
C271-pineal-spinal-locus-globus-medulla-thalamus-cerebellum0
C272-CD19-CD4-CD8-Whole-Peripheral-lymph-tonsil0
C273-Neutrophils-CD14-Eosinophils-Monocytederived-CD4-Natural-Mast0
C274-CD14-Mast-immature-Basophils-mature-vagina-Hepatocyte0
C275-pons-medulla-cerebellum-locus-thalamus-diencephalon-spinal0
C276-mesothelioma-kidney-renal-small-clear-cerebellum-Renal0
C277-mesothelioma-epithelioid-thyroid-extraskeletal-alveolar-glioblastoma-adenocarcinoma0
C278-amygdala-hippocampus-insula-medial-putamen-temporal-olfactory0
C279-parietal-cerebellum-occipital-temporal-middle-duodenum-medial0
C28-thymus-acute-vein-Hodgkin-chronic-throat-Dendritic0
C280-Mast-Natural-CD19-CD8-Eosinophils-CD34-CD40.0633
C281-Hodgkin-Reticulocytes-chronic-NK-acute-retinoblastoma-small0.428
C282-acute-B-tonsil-CD19-submaxillary-lymph-throat0
C283-tenocyte-Chondrocyte-mesenchymal-Macrophage-pleomorphic-Synoviocyte-cholangiocellular0
C284-parietal-occipital-medial-temporal-olfactory-locus-hippocampus0
C285-cervical-Hep2-small-colon-temporal-duodenum-bronchogenic0
C286-cerebellum-occipital-optic-parietal-globus-caudate-medial0
C287-Hepatocyte-Chondrocyte-Adipocyte-Synoviocyte-liver-tenocyte-mesenchymal0
C288-Chondrocyte-Renal-Pericytes-Fibroblast-aorta-Smooth-Meningeal0
C289-chorionic-skeletal-heart-Mast-amniotic-granulosa-left0
C29-mature-adipose-Adipocyte-breast-Lymphatic-vein-heart0
C290-Eosinophils-CD14-Basophils-Mast-CD4-CD8-immature0.012
C291-spinal-substantia-retina-medulla-tongue-skeletal-trachea0
C292-Mesenchymal-skin-umbilical-Adipocyte-mesenchymal-Chondrocyte-skeletal0
C293-CD14-CD14CD16-Basophils-Peripheral-immature-Eosinophils-CD340
C294-CD14-Macrophage-Monocytederived-CD14CD16-Neutrophils-Basophils-Peripheral0.0633
C295-Fibroblast-Smooth-Myoblast-Chondrocyte-hepatic-Synoviocyte-Preadipocyte0
C296-gall-small-mesothelioma-acute-bronchioalveolar-epidermoid-mixed0
C297-Eosinophils-CD4-Basophils-Natural-Neutrophils-CD8-Peripheral0.0127
C298-small-optic-substantia-thalamus-diencephalon-globus-occipital0
C299-CD14CD16-Eosinophils-Neutrophils-CD14-Whole-Basophils-blood0.0633
C3-occipital-temporal-insula-medial-postcentral-frontal-amygdala0
C30-thyroid-throat-mesothelioma-mucinous-trachea-chorionic-mesenchymal0
C300-CD4-CD8-NK-Natural-blood-mycosis-Basophils0
C301-Smooth-mesenchymal-Endothelial-Hepatic-basal-hepatic-chorionic0
C302-acute-peripheral-Neutrophils-NK-myelodysplastic-CD34-carcinoid0
C303-CD14-Basophils-Peripheral-Eosinophils-CD14CD16-Neutrophils-Whole0
C305-heart-skeletal-smooth-left-bladder-penis-esophagus0
C31-skeletal-tongue-diaphragm-throat-penis-skin-trachea0
C32-middle-occipital-parietal-hippocampus-amygdala-medial-olfactory0
C33-Reticulocytes-liver-Whole-blood-chronic-acute-spleen0
C34-placenta-chorionic-choriocarcinoma-mesothelioma-Wilms-Smooth-bile0
C35-caudate-putamen-diencephalon-nucleus-globus-thalamus-insula0
C36-B-b-splenic-plasma-xeroderma-adrenal-Burkitt0
C37-salivary-submaxillary-parotid-seminal-tongue-ductus-trachea0
C38-extraskeletal-rhabdomyosarcoma-adrenal-rectal-mesothelioma-lung-Wilms0
C39-epididymis-ductus-seminal-testis-acute-thyroid-CD1330
C4-optic-corpus-substantia-medulla-spinal-thalamus-globus0
C40-eye-retina-Lens-pineal-tongue-retinoblastoma-small0
C41-retina-eye-medulla-Retinal-medulloblastoma-kidney-pineal0
C42-small-lung-maxillary-pharyngeal-Mesenchymal-Wilms-colon0
C43-ductus-seminal-duodenum-temporal-gall-prostate-bladder0
C44-Dendritic-CD19-CD133-granulocyte-acute-thymus-immature0
C45-testicular-choriocarcinoma-H9-teratocarcinoma-Wilms-pancreatic-iPS0
C46-acute-Hodgkin-thymus-CD8-chronic-CD4-merkel0
C47-CD19-Burkitt-acute-xeroderma-tonsil-lymphoma-appendix0
C48-smooth-bladder-esophagus-colon-penis-aorta-uterus0
C49-H9-iPS-testicular-HES3GFP-teratocarcinoma-hepatoblastoma-choriocarcinoma0
C5-Hepatocyte-liver-hepatocellular-Intestinal-kidney-small-pancreas0
C50-chorionic-placenta-amniotic-migratory-smallcell-chronic-choriocarcinoma0
C51-kidney-mesothelioma-renal-signet-gall-lung-pancreas0
C52-adult-NK-chronic-cord-testis-embryonic-myeloma0
C53-medulloblastoma-pineal-retinoblastoma-small-retina-eye-pituitary0
C54-Dendritic-Macrophage-Monocytederived-CD14-leiomyoma-adipose-immature0
C55-hepatocellular-Intestinal-liver-Prostate-fibrosarcoma-Hepatocyte-hepatoblastoma0
C56-heart-left-umbilical-skeletal-penis-diaphragm-tongue0
C57-Neutrophils-Eosinophils-Whole-CD4-CD8-CD19-Natural0.212
C58-Melanocyte-melanoma-retina-Retinal-eye-migratory-H90
C59-Smooth-Fibroblast-Mesenchymal-tenocyte-Ewing-skin-hepatic0
C6-CD14-Eosinophils-Basophils-Peripheral-CD34-Natural-immature0
C60-esophagus-tonsil-throat-tongue-uterus-cervix-cervical0
C61-migratory-Dendritic-immature-Macrophage-xeroderma-cord-b0
C62-Burkitt-tonsil-CD19-submaxillary-spleen-salivary-lymph0
C63-neuroectodermal-neuroblastoma-carcinoid-peripheral-chronic-neuroepithelioma-acute0
C64-Mast-chronic-acute-immature-chorionic-Basophils-Dendritic0
C65-CD14-Eosinophils-Monocytederived-Basophils-immature-Macrophage-Neutrophils0
C66-cerebellum-middle-occipital-parietal-medial-amygdala-hippocampus0
C67-CD14-Monocytederived-Macrophage-dura-Dendritic-spleen-lung0
C68-amniotic-chorionic-Placental-salivary-placenta-tongue-mesothelioma0
C69-anaplastic-CD14-cord-hairy-mycosis-adult-NK0
C7-CD14-Eosinophils-Neutrophils-Smooth-Basophils-Macrophage-Mast0
C70-parotid-submaxillary-salivary-throat-trachea-aorta-tongue0
C71-Monocytederived-Macrophage-CD14-Dendritic-Osteoblast-leiomyoma-Prostate0
C72-skeletal-tongue-throat-heart-diaphragm-penis-left0
C73-pineal-eye-retina-caudate-cerebellum-left-parietal0
C74-splenic-B-b-plasma-xeroderma-lymphoma-hairy0
C75-Eosinophils-Natural-CD8-Basophils-CD14-CD4-Peripheral0
C76-argyrophil-gastrointestinal-temporal-duodenum-neuroblastoma-merkel-smallcell0
C77-Saos2-osteosarcoma-Neutrophils-Natural-Chondrocyte-Basophils-CD80
C78-lymphoma-plasma-tonsil-appendix-lymph-seminal-trachea0
C79-chorionic-Chondrocyte-Cardiac-Smooth-Fibroblast-Preadipocyte-Mesenchymal0
C8-Natural-CD8-Basophils-CD4-CD14-Peripheral-CD340
C80-immature-migratory-CD14-Dendritic-splenic-cord-Mast0
C81-trachea-salivary-throat-aorta-eye-submaxillary-parotid0
C82-Basophils-CD14-Eosinophils-Natural-Peripheral-immature-CD340
C83-choriocarcinoma-pancreatic-placenta-chorionic-HES3GFP-testicular-amniotic0
C84-choriocarcinoma-pancreatic-Wilms-Mallassezderived-thymus-salivary-colon0
C85-neuroblastoma-carcinoid-retinoblastoma-small-pineal-rhabdomyosarcoma-medulloblastoma0
C86-colon-carcinoid-small-neuroectodermal-giant-large-neuroepithelioma0
C87-retinoblastoma-left-nonsmall-heart-small-diaphragm-bronchogenic0
C88-Melanocyte-melanoma-Macrophage-Mesenchymal-migratory-Dendritic-Monocytederived0
C89-small-retinoblastoma-medulloblastoma-iPS-acantholytic-eye-bronchogenic0
C9-skeletal-diaphragm-tongue-throat-penis-heart-left0
C90-neuroectodermal-peripheral-neuroepithelioma-neuroblastoma-carcinoid-parietal-putamen0
C91-Fibroblast-Smooth-mesenchymal-Mesothelial-Small-Preadipocyte-Hair0
C92-CD14CD16-CD14-Eosinophils-Basophils-Neutrophils-Macrophage-Whole0
C93-chronic-acute-leukemia-acantholytic-medulloblastoma-testis-papillotubular0
C94-smallcell-adrenal-lung-nonsmall-small-somatostatinoma-teratocarcinoma0
C95-lung-aorta-trachea-penis-Alveolar-throat-endometrioid0
C96-non-acute-tonsil-spleen-Burkitt-lymphoma-appendix0
C97-small-smallcell-gastrointestinal-argyrophil-putamen-duodenum-brain0
C98-CD8-Natural-Basophils-blood-CD4-Peripheral-Whole0
C99-hairy-mycosis-submaxillary-salivary-cord-kidney-parotid0



Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data



TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample


JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs11886

Jaspar motifP-value
MA0002.27.49377e-5
MA0003.10.658
MA0004.10.036
MA0006.10.17
MA0007.10.179
MA0009.10.409
MA0014.10.67
MA0017.10.026
MA0018.20.0121
MA0019.10.0342
MA0024.16.46613e-5
MA0025.10.0994
MA0027.10.263
MA0028.14.14704e-5
MA0029.10.301
MA0030.10.0555
MA0031.10.124
MA0035.20.00603
MA0038.13.62458e-4
MA0039.20.372
MA0040.10.527
MA0041.10.158
MA0042.10.391
MA0043.10.0128
MA0046.10.514
MA0047.20.0754
MA0048.10.0952
MA0050.10.18
MA0051.10.0698
MA0052.10.117
MA0055.10.00826
MA0057.10.287
MA0058.10.0226
MA0059.12.13901e-5
MA0060.10.0388
MA0061.10.616
MA0062.21.28291e-9
MA0065.20.00412
MA0066.10.702
MA0067.10.897
MA0068.10.774
MA0069.10.124
MA0070.10.807
MA0071.10.162
MA0072.10.529
MA0073.10.426
MA0074.10.997
MA0076.11.35297e-4
MA0077.10.111
MA0078.10.988
MA0079.20.578
MA0080.22.80547e-10
MA0081.10.0153
MA0083.10.0791
MA0084.10.674
MA0087.10.354
MA0088.19.11423e-4
MA0090.16.59444e-4
MA0091.10.67
MA0092.10.889
MA0093.10.0279
MA0099.20.00701
MA0100.10.00334
MA0101.10.306
MA0102.20.652
MA0103.10.584
MA0104.23.5745e-5
MA0105.10.207
MA0106.10.378
MA0107.10.0189
MA0108.25.53959e-6
MA0111.10.724
MA0112.20.384
MA0113.10.985
MA0114.10.131
MA0115.10.146
MA0116.11.2672e-4
MA0117.10.872
MA0119.10.282
MA0122.10.519
MA0124.10.766
MA0125.10.848
MA0131.10.0811
MA0135.10.728
MA0136.12.15417e-15
MA0137.20.227
MA0138.20.714
MA0139.10.108
MA0140.10.00167
MA0141.10.0261
MA0142.10.409
MA0143.10.757
MA0144.10.385
MA0145.10.188
MA0146.10.00213
MA0147.11.16615e-6
MA0148.10.0293
MA0149.10.0481
MA0150.10.948
MA0152.10.92
MA0153.10.099
MA0154.10.077
MA0155.10.94
MA0156.11.92247e-12
MA0157.10.896
MA0159.10.962
MA0160.10.012
MA0162.10.624
MA0163.13.02869e-13
MA0164.10.806
MA0258.10.183
MA0259.10.0163



FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs11886

Novel motifP-value
10.14
100.00648
1000.58
1010.737
1020.404
1030.83
1040.804
1050.966
1060.68
1070.837
1080.501
1090.0793
110.0515
1100.118
1110.0802
1120.586
1130.987
1140.0376
1150.807
1160.197
1170.0133
1180.0319
1190.897
120.886
1200.274
1210.833
1220.843
1230.00771
1240.466
1250.24
1260.493
1270.0801
1280.465
1290.695
130.00211
1300.795
1310.389
1320.622
1330.622
1340.917
1350.596
1360.204
1370.459
1380.279
1390.978
140.891
1400.333
1410.114
1420.482
1430.212
1440.295
1450.206
1460.623
1470.00872
1480.0601
1490.221
150.255
1500.705
1510.79
1520.663
1530.595
1540.892
1550.0387
1560.27
1570.167
1580.869
1590.364
160.397
1600.386
1610.18
1620.455
1630.999
1640.111
1650.527
1660.0499
1670.173
1680.107
1690.0307
170.858
180.206
190.923
20.568
200.218
210.302
220.387
230.0428
240.184
250.144
260.0237
270.816
280.853
290.12
30.144
300.1
310.187
320.00978
330.502
340.749
350.659
360.0653
370.251
380.41
390.212
40.284
400.347
410.86
420.259
430.607
440.0218
450.42
460.0739
470.0299
480.00765
490.249
50.757
500.955
510.655
520.0973
530.123
540.975
550.109
560.95
570.035
580.13
590.469
60.333
600.777
610.0437
620.158
630.554
640.136
650.761
660.0533
670.471
680.908
690.871
70.0395
700.882
710.0317
720.683
730.179
740.654
750.0101
760.0648
770.844
780.0722
790.393
80.0556
800.0787
810.646
820.981
830.398
840.339
850.232
860.783
870.127
880.446
890.625
90.749
900.496
910.666
920.281
930.438
940.935
950.00306
960.367
970.281
980.219
990.557



de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br> library id: CNhs11886


FANTOM5 (FF) ontology


Direct parent terms


Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data

CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000255 (eukaryotic cell)

DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
2531 (hematologic cancer)
14566 (disease of cellular proliferation)
0060083 (immune system cancer)
1240 (leukemia)
1036 (chronic leukemia)
8692 (myeloid leukemia)

FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100737 (leukemia cell line sample)
0102580 (chronic myeloid leukemia cell line sample)
0101035 (hematopoietic cell line sample)
0100740 (myeloid leukemia cell line sample)
0104137 (KCL-22 cell sample)

Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)