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{{f5samples
{{f5samples
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Line 35: Line 41:
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|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11841
|name=serous adenocarcinoma cell line:SK-OV-3-R, biol_rep1
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Line 42: Line 60:
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Line 57: Line 78:
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Line 69: Line 91:
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|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;5.86168898791834e-252!GO:0043226;organelle;1.8161103532722e-205!GO:0043229;intracellular organelle;6.20737499427044e-205!GO:0043231;intracellular membrane-bound organelle;3.73220307005751e-203!GO:0043227;membrane-bound organelle;5.31950443558496e-203!GO:0005737;cytoplasm;1.40664962876165e-179!GO:0044422;organelle part;5.86439567615042e-167!GO:0044446;intracellular organelle part;2.9032657268385e-165!GO:0044444;cytoplasmic part;8.10774786161652e-128!GO:0032991;macromolecular complex;1.06727245538111e-118!GO:0030529;ribonucleoprotein complex;5.06897936400334e-95!GO:0044237;cellular metabolic process;8.9998052362761e-95!GO:0044238;primary metabolic process;3.95856589057402e-92!GO:0043170;macromolecule metabolic process;9.82995714304757e-89!GO:0005634;nucleus;1.93824141377235e-86!GO:0044428;nuclear part;1.35140401369863e-80!GO:0043233;organelle lumen;4.8968098597049e-76!GO:0031974;membrane-enclosed lumen;4.8968098597049e-76!GO:0003723;RNA binding;3.23671337436973e-70!GO:0005739;mitochondrion;5.74743527753386e-70!GO:0005515;protein binding;1.13327755091308e-69!GO:0043234;protein complex;1.40598994740803e-61!GO:0005840;ribosome;4.05639200822435e-57!GO:0031090;organelle membrane;4.35826838796791e-54!GO:0006412;translation;1.84488857281703e-53!GO:0043283;biopolymer metabolic process;1.48949930340671e-51!GO:0016043;cellular component organization and biogenesis;6.95668954473761e-51!GO:0006396;RNA processing;7.69885936795419e-51!GO:0003735;structural constituent of ribosome;3.23673235504901e-50!GO:0019538;protein metabolic process;1.53017797667495e-49!GO:0031981;nuclear lumen;6.13316580278792e-47!GO:0044429;mitochondrial part;8.0895187106479e-47!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.34986660057012e-45!GO:0010467;gene expression;1.07267136543268e-44!GO:0044260;cellular macromolecule metabolic process;7.18160458555214e-44!GO:0044267;cellular protein metabolic process;1.80189796345385e-43!GO:0015031;protein transport;1.02476619309886e-42!GO:0031967;organelle envelope;1.53293413344941e-42!GO:0031975;envelope;1.75807660599436e-42!GO:0033036;macromolecule localization;3.33029416232691e-42!GO:0044249;cellular biosynthetic process;4.34701678309743e-42!GO:0033279;ribosomal subunit;4.69767013651248e-42!GO:0043228;non-membrane-bound organelle;9.4563686533328e-42!GO:0043232;intracellular non-membrane-bound organelle;9.4563686533328e-42!GO:0009058;biosynthetic process;2.76278663283192e-41!GO:0009059;macromolecule biosynthetic process;4.17956234623993e-40!GO:0005829;cytosol;2.60621643337695e-39!GO:0045184;establishment of protein localization;4.73906621158698e-39!GO:0016071;mRNA metabolic process;6.29322698925849e-39!GO:0008104;protein localization;2.06718253243276e-38!GO:0006996;organelle organization and biogenesis;1.15532614672312e-37!GO:0008380;RNA splicing;1.32112079672067e-37!GO:0046907;intracellular transport;2.7907247352046e-36!GO:0065003;macromolecular complex assembly;3.19666415805426e-35!GO:0006397;mRNA processing;7.50118502075684e-35!GO:0006259;DNA metabolic process;9.76301357587173e-34!GO:0022613;ribonucleoprotein complex biogenesis and assembly;6.10197646890337e-33!GO:0022607;cellular component assembly;8.21305490777977e-31!GO:0006886;intracellular protein transport;1.18989172944409e-29!GO:0005830;cytosolic ribosome (sensu Eukaryota);3.00361938488042e-29!GO:0005740;mitochondrial envelope;3.27956168264956e-29!GO:0019866;organelle inner membrane;2.148055334436e-28!GO:0005681;spliceosome;5.40133989657255e-28!GO:0031966;mitochondrial membrane;8.02843751981604e-28!GO:0005654;nucleoplasm;1.03191457764911e-27!GO:0003676;nucleic acid binding;1.45612070404805e-26!GO:0007049;cell cycle;4.09162547330979e-26!GO:0005743;mitochondrial inner membrane;9.12597234729497e-26!GO:0051641;cellular localization;5.51106532029366e-24!GO:0051649;establishment of cellular localization;8.77405565446977e-24!GO:0016462;pyrophosphatase activity;1.87183182865782e-23!GO:0000166;nucleotide binding;2.52952319142188e-23!GO:0012505;endomembrane system;3.05202564860958e-23!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;3.87752415214825e-23!GO:0016817;hydrolase activity, acting on acid anhydrides;6.45009243454126e-23!GO:0017111;nucleoside-triphosphatase activity;1.79061229665635e-22!GO:0044445;cytosolic part;2.48221853007393e-22!GO:0044451;nucleoplasm part;3.31560592007881e-22!GO:0015934;large ribosomal subunit;3.32785050892332e-22!GO:0006119;oxidative phosphorylation;1.35542286710514e-21!GO:0005694;chromosome;6.0119426765521e-21!GO:0006457;protein folding;6.0119426765521e-21!GO:0015935;small ribosomal subunit;6.87965245906297e-21!GO:0044455;mitochondrial membrane part;6.96901488689768e-21!GO:0000278;mitotic cell cycle;7.15125808329251e-21!GO:0016070;RNA metabolic process;3.203599020341e-20!GO:0031980;mitochondrial lumen;3.77014849996807e-20!GO:0005759;mitochondrial matrix;3.77014849996807e-20!GO:0044427;chromosomal part;6.98719307172054e-20!GO:0022618;protein-RNA complex assembly;8.08736914999976e-20!GO:0005730;nucleolus;1.11093772697741e-19!GO:0022402;cell cycle process;3.17832494943696e-19!GO:0006974;response to DNA damage stimulus;3.38872798260094e-18!GO:0000502;proteasome complex (sensu Eukaryota);4.52367948591963e-18!GO:0016874;ligase activity;1.48845188391864e-17!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;1.50302259560486e-17!GO:0005761;mitochondrial ribosome;2.56757206306678e-17!GO:0000313;organellar ribosome;2.56757206306678e-17!GO:0000087;M phase of mitotic cell cycle;3.39046162153511e-17!GO:0007067;mitosis;6.51612973255259e-17!GO:0051186;cofactor metabolic process;7.0535871700499e-17!GO:0032553;ribonucleotide binding;1.18619238570703e-16!GO:0032555;purine ribonucleotide binding;1.18619238570703e-16!GO:0005783;endoplasmic reticulum;1.18996097728788e-16!GO:0050136;NADH dehydrogenase (quinone) activity;1.68661274707482e-16!GO:0003954;NADH dehydrogenase activity;1.68661274707482e-16!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.68661274707482e-16!GO:0017076;purine nucleotide binding;1.96617584600164e-16!GO:0006512;ubiquitin cycle;2.05686117723327e-16!GO:0008135;translation factor activity, nucleic acid binding;4.73001471946991e-16!GO:0051276;chromosome organization and biogenesis;5.91660906180002e-16!GO:0051082;unfolded protein binding;9.28261405892192e-16!GO:0043285;biopolymer catabolic process;9.87942513984855e-16!GO:0044265;cellular macromolecule catabolic process;9.96407715930764e-16!GO:0044432;endoplasmic reticulum part;1.01514012101164e-15!GO:0005746;mitochondrial respiratory chain;1.02820561573747e-15!GO:0022403;cell cycle phase;2.54645231596499e-15!GO:0006605;protein targeting;2.82368178524985e-15!GO:0006281;DNA repair;2.85027966889926e-15!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);3.68679395936113e-15!GO:0006260;DNA replication;6.74902723131911e-15!GO:0009057;macromolecule catabolic process;1.17188105432322e-14!GO:0005524;ATP binding;1.23949637019976e-14!GO:0008134;transcription factor binding;1.27413520082699e-14!GO:0005794;Golgi apparatus;1.55506442825231e-14!GO:0032559;adenyl ribonucleotide binding;1.96069728808588e-14!GO:0048770;pigment granule;2.44559487637605e-14!GO:0042470;melanosome;2.44559487637605e-14!GO:0030964;NADH dehydrogenase complex (quinone);2.97172628599864e-14!GO:0045271;respiratory chain complex I;2.97172628599864e-14!GO:0005747;mitochondrial respiratory chain complex I;2.97172628599864e-14!GO:0051301;cell division;3.5606750071093e-14!GO:0031965;nuclear membrane;3.69166428962335e-14!GO:0000398;nuclear mRNA splicing, via spliceosome;3.69364355320566e-14!GO:0000375;RNA splicing, via transesterification reactions;3.69364355320566e-14!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;3.69364355320566e-14!GO:0005635;nuclear envelope;4.0319631400282e-14!GO:0051603;proteolysis involved in cellular protein catabolic process;4.6298617595705e-14!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);4.6298617595705e-14!GO:0030554;adenyl nucleotide binding;4.67347173123356e-14!GO:0044453;nuclear membrane part;6.91724872246094e-14!GO:0044257;cellular protein catabolic process;7.62161033084497e-14!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;9.19142063082863e-14!GO:0019941;modification-dependent protein catabolic process;9.46216604220496e-14!GO:0043632;modification-dependent macromolecule catabolic process;9.46216604220496e-14!GO:0042254;ribosome biogenesis and assembly;9.81804821110288e-14!GO:0006511;ubiquitin-dependent protein catabolic process;1.03133132011383e-13!GO:0000279;M phase;1.26761689239229e-13!GO:0016887;ATPase activity;1.41475400479084e-13!GO:0006732;coenzyme metabolic process;2.47254201456351e-13!GO:0003743;translation initiation factor activity;4.5113439708644e-13!GO:0030163;protein catabolic process;4.69822599650476e-13!GO:0006325;establishment and/or maintenance of chromatin architecture;4.69822599650476e-13!GO:0048193;Golgi vesicle transport;4.8082200474381e-13!GO:0006413;translational initiation;5.84776157061725e-13!GO:0042623;ATPase activity, coupled;6.50225592840132e-13!GO:0044248;cellular catabolic process;8.16754102853468e-13!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.17672293147748e-12!GO:0065004;protein-DNA complex assembly;1.30787334298221e-12!GO:0009719;response to endogenous stimulus;1.37057444527818e-12!GO:0000785;chromatin;1.51819523105527e-12!GO:0006323;DNA packaging;1.53836631127715e-12!GO:0042175;nuclear envelope-endoplasmic reticulum network;2.62091381070753e-12!GO:0042775;organelle ATP synthesis coupled electron transport;3.68151703321635e-12!GO:0042773;ATP synthesis coupled electron transport;3.68151703321635e-12!GO:0005789;endoplasmic reticulum membrane;7.05234721950682e-12!GO:0043412;biopolymer modification;9.68038498722696e-12!GO:0006399;tRNA metabolic process;1.75308988728685e-11!GO:0015630;microtubule cytoskeleton;1.94932347799653e-11!GO:0009055;electron carrier activity;2.73605252033674e-11!GO:0006333;chromatin assembly or disassembly;2.82976264895025e-11!GO:0005643;nuclear pore;2.96123038672299e-11!GO:0006446;regulation of translational initiation;3.80293507566404e-11!GO:0006913;nucleocytoplasmic transport;3.85145763908156e-11!GO:0006334;nucleosome assembly;4.59001776728848e-11!GO:0051169;nuclear transport;9.87689082589218e-11!GO:0003712;transcription cofactor activity;2.41541813893938e-10!GO:0016192;vesicle-mediated transport;2.47829466883938e-10!GO:0009259;ribonucleotide metabolic process;2.87909833823121e-10!GO:0006464;protein modification process;3.53577278379585e-10!GO:0065002;intracellular protein transport across a membrane;4.11456757282376e-10!GO:0008565;protein transporter activity;4.52331155265324e-10!GO:0006163;purine nucleotide metabolic process;5.43572759071946e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;7.21173600482036e-10!GO:0006403;RNA localization;7.3733694951727e-10!GO:0051188;cofactor biosynthetic process;7.42471890642151e-10!GO:0031497;chromatin assembly;7.78699219667682e-10!GO:0008639;small protein conjugating enzyme activity;9.48082132734321e-10!GO:0016604;nuclear body;1.31952629941301e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;1.3386435332477e-09!GO:0005793;ER-Golgi intermediate compartment;1.36734673676335e-09!GO:0004842;ubiquitin-protein ligase activity;1.48920311022464e-09!GO:0050657;nucleic acid transport;1.49416376181582e-09!GO:0051236;establishment of RNA localization;1.49416376181582e-09!GO:0050658;RNA transport;1.49416376181582e-09!GO:0019787;small conjugating protein ligase activity;1.54235489004253e-09!GO:0043687;post-translational protein modification;1.84040929486377e-09!GO:0006164;purine nucleotide biosynthetic process;2.13639844969991e-09!GO:0009150;purine ribonucleotide metabolic process;2.56591597598589e-09!GO:0006366;transcription from RNA polymerase II promoter;2.65415605061437e-09!GO:0046930;pore complex;2.90384099669578e-09!GO:0000074;regulation of progression through cell cycle;3.30663052480938e-09!GO:0009260;ribonucleotide biosynthetic process;3.34332296937276e-09!GO:0012501;programmed cell death;3.38356243840598e-09!GO:0051726;regulation of cell cycle;3.78746310827303e-09!GO:0030532;small nuclear ribonucleoprotein complex;3.97951761804116e-09!GO:0004386;helicase activity;4.20796776509849e-09!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;5.82078285450085e-09!GO:0006915;apoptosis;6.89842962358103e-09!GO:0009141;nucleoside triphosphate metabolic process;9.44897467107371e-09!GO:0006364;rRNA processing;9.81418154837501e-09!GO:0017038;protein import;9.81418154837501e-09!GO:0009152;purine ribonucleotide biosynthetic process;1.01412036987508e-08!GO:0015986;ATP synthesis coupled proton transport;1.01939107136223e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.01939107136223e-08!GO:0005768;endosome;1.02748652976003e-08!GO:0009199;ribonucleoside triphosphate metabolic process;1.0997355095051e-08!GO:0016879;ligase activity, forming carbon-nitrogen bonds;1.14800337161685e-08!GO:0016072;rRNA metabolic process;1.64821591130848e-08!GO:0009205;purine ribonucleoside triphosphate metabolic process;2.10928384827272e-08!GO:0009144;purine nucleoside triphosphate metabolic process;2.10928384827272e-08!GO:0009142;nucleoside triphosphate biosynthetic process;2.10967466681362e-08!GO:0009201;ribonucleoside triphosphate biosynthetic process;2.10967466681362e-08!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;2.12030085816796e-08!GO:0004812;aminoacyl-tRNA ligase activity;2.12030085816796e-08!GO:0016875;ligase activity, forming carbon-oxygen bonds;2.12030085816796e-08!GO:0008026;ATP-dependent helicase activity;2.63636824304966e-08!GO:0006461;protein complex assembly;2.81037353379735e-08!GO:0007005;mitochondrion organization and biogenesis;2.98692142366003e-08!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;4.09683431204246e-08!GO:0009145;purine nucleoside triphosphate biosynthetic process;4.09683431204246e-08!GO:0008219;cell death;4.09683431204246e-08!GO:0016265;death;4.09683431204246e-08!GO:0019829;cation-transporting ATPase activity;4.15267503144818e-08!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;4.42314803258813e-08!GO:0043038;amino acid activation;4.43453604654545e-08!GO:0006418;tRNA aminoacylation for protein translation;4.43453604654545e-08!GO:0043039;tRNA aminoacylation;4.43453604654545e-08!GO:0005667;transcription factor complex;5.40638582037231e-08!GO:0009108;coenzyme biosynthetic process;6.38895702758675e-08!GO:0046034;ATP metabolic process;6.53800773315748e-08!GO:0005839;proteasome core complex (sensu Eukaryota);8.36745753511142e-08!GO:0051028;mRNA transport;8.42709507348906e-08!GO:0006888;ER to Golgi vesicle-mediated transport;8.68973723040971e-08!GO:0006754;ATP biosynthetic process;9.44411448148066e-08!GO:0006753;nucleoside phosphate metabolic process;9.44411448148066e-08!GO:0016607;nuclear speck;9.45242938743254e-08!GO:0016881;acid-amino acid ligase activity;9.48102519185675e-08!GO:0009117;nucleotide metabolic process;1.11692993243823e-07!GO:0005813;centrosome;1.553046765485e-07!GO:0005819;spindle;1.90045090466566e-07!GO:0009056;catabolic process;2.00370859532153e-07!GO:0048523;negative regulation of cellular process;2.73434413735828e-07!GO:0000786;nucleosome;2.84997666626052e-07!GO:0032446;protein modification by small protein conjugation;2.99118764267015e-07!GO:0005815;microtubule organizing center;3.8310505517757e-07!GO:0003924;GTPase activity;3.85741478793944e-07!GO:0044431;Golgi apparatus part;4.35723836819615e-07!GO:0050794;regulation of cellular process;4.446037222464e-07!GO:0043069;negative regulation of programmed cell death;4.48056073423941e-07!GO:0004298;threonine endopeptidase activity;4.91766963284257e-07!GO:0030120;vesicle coat;5.40018500595639e-07!GO:0030662;coated vesicle membrane;5.40018500595639e-07!GO:0016787;hydrolase activity;5.70241145527451e-07!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;6.114040236465e-07!GO:0045259;proton-transporting ATP synthase complex;6.24014157655107e-07!GO:0016567;protein ubiquitination;6.41542608429136e-07!GO:0016740;transferase activity;6.41542608429136e-07!GO:0000775;chromosome, pericentric region;7.18476259188163e-07!GO:0016779;nucleotidyltransferase activity;9.16749398097228e-07!GO:0000245;spliceosome assembly;9.23890336652209e-07!GO:0043566;structure-specific DNA binding;9.91806612765136e-07!GO:0006752;group transfer coenzyme metabolic process;1.07970098162199e-06!GO:0006099;tricarboxylic acid cycle;1.10396253146428e-06!GO:0046356;acetyl-CoA catabolic process;1.10396253146428e-06!GO:0016563;transcription activator activity;1.17778957434273e-06!GO:0043066;negative regulation of apoptosis;1.20582535446689e-06!GO:0048475;coated membrane;1.65216379062497e-06!GO:0030117;membrane coat;1.65216379062497e-06!GO:0016469;proton-transporting two-sector ATPase complex;1.70233445344739e-06!GO:0006084;acetyl-CoA metabolic process;1.77853597950152e-06!GO:0051246;regulation of protein metabolic process;1.77853597950152e-06!GO:0016491;oxidoreductase activity;1.84657365059169e-06!GO:0006916;anti-apoptosis;1.86915164866675e-06!GO:0005762;mitochondrial large ribosomal subunit;2.48037630684674e-06!GO:0000315;organellar large ribosomal subunit;2.48037630684674e-06!GO:0015078;hydrogen ion transmembrane transporter activity;3.04674520471599e-06!GO:0044440;endosomal part;3.25107781056392e-06!GO:0010008;endosome membrane;3.25107781056392e-06!GO:0009060;aerobic respiration;3.42961953902925e-06!GO:0051187;cofactor catabolic process;3.75313464816204e-06!GO:0016568;chromatin modification;4.51435602154678e-06!GO:0006261;DNA-dependent DNA replication;4.57389915619937e-06!GO:0048519;negative regulation of biological process;4.59076025484782e-06!GO:0006091;generation of precursor metabolites and energy;4.67054756203505e-06!GO:0003724;RNA helicase activity;5.35096538337148e-06!GO:0051170;nuclear import;5.77971554667801e-06!GO:0005657;replication fork;6.13864957158068e-06!GO:0031324;negative regulation of cellular metabolic process;7.50395368426807e-06!GO:0043067;regulation of programmed cell death;7.802728898074e-06!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;9.02662745863808e-06!GO:0007051;spindle organization and biogenesis;9.14679850943392e-06!GO:0003899;DNA-directed RNA polymerase activity;9.78757230550548e-06!GO:0008654;phospholipid biosynthetic process;9.79272110163136e-06!GO:0042981;regulation of apoptosis;1.12334722488111e-05!GO:0009109;coenzyme catabolic process;1.12619397907463e-05!GO:0000314;organellar small ribosomal subunit;1.2292529219046e-05!GO:0005763;mitochondrial small ribosomal subunit;1.2292529219046e-05!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.3136400445805e-05!GO:0043623;cellular protein complex assembly;1.39656008676209e-05!GO:0000151;ubiquitin ligase complex;1.47204989895706e-05!GO:0005769;early endosome;1.52720740466854e-05!GO:0006613;cotranslational protein targeting to membrane;1.60700738659998e-05!GO:0006606;protein import into nucleus;1.64495938775946e-05!GO:0003713;transcription coactivator activity;1.78485364937148e-05!GO:0045333;cellular respiration;2.25272227005462e-05!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;2.59829043670167e-05!GO:0005788;endoplasmic reticulum lumen;2.62046908482702e-05!GO:0000139;Golgi membrane;2.68980968282588e-05!GO:0006793;phosphorus metabolic process;2.77246793304762e-05!GO:0006796;phosphate metabolic process;2.77246793304762e-05!GO:0043021;ribonucleoprotein binding;2.87197126308794e-05!GO:0051427;hormone receptor binding;2.96057019247599e-05!GO:0003697;single-stranded DNA binding;3.09847258660303e-05!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;3.82530956812182e-05!GO:0015399;primary active transmembrane transporter activity;3.82530956812182e-05!GO:0003714;transcription corepressor activity;4.42787639662617e-05!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;4.92199852118867e-05!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;4.92199852118867e-05!GO:0051329;interphase of mitotic cell cycle;5.58762413948665e-05!GO:0016564;transcription repressor activity;5.68223343181465e-05!GO:0005852;eukaryotic translation initiation factor 3 complex;5.76007306932865e-05!GO:0007010;cytoskeleton organization and biogenesis;6.276531710745e-05!GO:0005798;Golgi-associated vesicle;6.83746206032557e-05!GO:0035257;nuclear hormone receptor binding;6.88053084231904e-05!GO:0007249;I-kappaB kinase/NF-kappaB cascade;6.88705924703909e-05!GO:0015077;monovalent inorganic cation transmembrane transporter activity;7.51396163867368e-05!GO:0005874;microtubule;7.68226833629209e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;8.04535965923704e-05!GO:0051168;nuclear export;8.56954454060821e-05!GO:0030867;rough endoplasmic reticulum membrane;8.82195657486558e-05!GO:0009892;negative regulation of metabolic process;9.51426901927129e-05!GO:0051325;interphase;9.67402936357549e-05!GO:0009165;nucleotide biosynthetic process;9.71773173357112e-05!GO:0019222;regulation of metabolic process;9.95776382055644e-05!GO:0016310;phosphorylation;0.00011246658067779!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000123269602840641!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.000129879889730697!GO:0005770;late endosome;0.000130875388808691!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.00013157789591626!GO:0008033;tRNA processing;0.000139003224259477!GO:0045454;cell redox homeostasis;0.000146641046385646!GO:0005525;GTP binding;0.000146702483330871!GO:0006626;protein targeting to mitochondrion;0.000147100268939234!GO:0033116;ER-Golgi intermediate compartment membrane;0.000199238354850142!GO:0000776;kinetochore;0.000201439285469992!GO:0043681;protein import into mitochondrion;0.000206934300642733!GO:0006612;protein targeting to membrane;0.000217092070246354!GO:0031252;leading edge;0.000221919134527758!GO:0046474;glycerophospholipid biosynthetic process;0.000223290330944872!GO:0046489;phosphoinositide biosynthetic process;0.000240937735072203!GO:0006383;transcription from RNA polymerase III promoter;0.000248061412798966!GO:0031072;heat shock protein binding;0.000249645787430911!GO:0048471;perinuclear region of cytoplasm;0.000251375058986318!GO:0003684;damaged DNA binding;0.00025273024928397!GO:0008186;RNA-dependent ATPase activity;0.000253664919030019!GO:0000075;cell cycle checkpoint;0.000273291495426406!GO:0008094;DNA-dependent ATPase activity;0.000273330575308042!GO:0016853;isomerase activity;0.000311635184853978!GO:0006302;double-strand break repair;0.000312262021798149!GO:0046483;heterocycle metabolic process;0.000313848060219123!GO:0044452;nucleolar part;0.000330289246073245!GO:0050789;regulation of biological process;0.000339411816834337!GO:0005885;Arp2/3 protein complex;0.00035253685968299!GO:0008250;oligosaccharyl transferase complex;0.000367325940719345!GO:0005048;signal sequence binding;0.000428857714052029!GO:0003690;double-stranded DNA binding;0.0004696058228263!GO:0016481;negative regulation of transcription;0.000470264571319497!GO:0031968;organelle outer membrane;0.000474482975120805!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.00048997374609369!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.000498432402745686!GO:0031988;membrane-bound vesicle;0.000498432402745686!GO:0019867;outer membrane;0.000510320232800696!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.000535611002760429!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000572630169638772!GO:0003729;mRNA binding;0.000572630169638772!GO:0051789;response to protein stimulus;0.000576951255604032!GO:0006986;response to unfolded protein;0.000576951255604032!GO:0016023;cytoplasmic membrane-bound vesicle;0.000604249200965979!GO:0016859;cis-trans isomerase activity;0.000675829407268319!GO:0000059;protein import into nucleus, docking;0.000686644358032729!GO:0004004;ATP-dependent RNA helicase activity;0.000695581556322649!GO:0006414;translational elongation;0.000706929901842831!GO:0007088;regulation of mitosis;0.000779871770369341!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0007822626437481!GO:0006839;mitochondrial transport;0.000809437598624458!GO:0051920;peroxiredoxin activity;0.000851234013610023!GO:0004576;oligosaccharyl transferase activity;0.000857876127726056!GO:0006352;transcription initiation;0.000919433744920822!GO:0019843;rRNA binding;0.000939750387434882!GO:0030176;integral to endoplasmic reticulum membrane;0.000963991690004689!GO:0005637;nuclear inner membrane;0.00108941754517226!GO:0005905;coated pit;0.00110820858967177!GO:0005741;mitochondrial outer membrane;0.00117341620918519!GO:0009112;nucleobase metabolic process;0.0012271269022717!GO:0051540;metal cluster binding;0.00122886698901697!GO:0051536;iron-sulfur cluster binding;0.00122886698901697!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00123277165468054!GO:0051252;regulation of RNA metabolic process;0.0012416714111085!GO:0043492;ATPase activity, coupled to movement of substances;0.00124168267819778!GO:0016272;prefoldin complex;0.00141765281866603!GO:0006497;protein amino acid lipidation;0.00143718318721651!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.00150252416694461!GO:0032561;guanyl ribonucleotide binding;0.00150252416694461!GO:0019001;guanyl nucleotide binding;0.00150252416694461!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00154639805144574!GO:0018196;peptidyl-asparagine modification;0.00155092088519012!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.00155092088519012!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00158939607086335!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00158939607086335!GO:0045786;negative regulation of progression through cell cycle;0.00162070350736323!GO:0006506;GPI anchor biosynthetic process;0.00165275835545399!GO:0005773;vacuole;0.00175977316891612!GO:0044262;cellular carbohydrate metabolic process;0.00181718020579485!GO:0051087;chaperone binding;0.00185546624264605!GO:0019899;enzyme binding;0.00190784763223654!GO:0005684;U2-dependent spliceosome;0.00191851674152478!GO:0006402;mRNA catabolic process;0.00192785483162458!GO:0030521;androgen receptor signaling pathway;0.00192785483162458!GO:0043284;biopolymer biosynthetic process;0.0020059140756812!GO:0006401;RNA catabolic process;0.0020719479367043!GO:0007093;mitotic cell cycle checkpoint;0.00209773124526437!GO:0042802;identical protein binding;0.00214399159757237!GO:0007006;mitochondrial membrane organization and biogenesis;0.00220608614150885!GO:0016363;nuclear matrix;0.00222112038646874!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00226180081647113!GO:0015980;energy derivation by oxidation of organic compounds;0.00231762405327348!GO:0048500;signal recognition particle;0.00242221602501834!GO:0030880;RNA polymerase complex;0.00244262861888445!GO:0048522;positive regulation of cellular process;0.00244912957308291!GO:0051052;regulation of DNA metabolic process;0.00269925525930612!GO:0006505;GPI anchor metabolic process;0.00278598838110279!GO:0007017;microtubule-based process;0.00289522316378088!GO:0005791;rough endoplasmic reticulum;0.0030108894775681!GO:0003711;transcription elongation regulator activity;0.00312660371945842!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00325116754638333!GO:0015631;tubulin binding;0.00326044044983219!GO:0030658;transport vesicle membrane;0.00334354745028547!GO:0006891;intra-Golgi vesicle-mediated transport;0.00334354745028547!GO:0031323;regulation of cellular metabolic process;0.00337068504924233!GO:0030384;phosphoinositide metabolic process;0.00341324602394212!GO:0007243;protein kinase cascade;0.00344313989933544!GO:0030132;clathrin coat of coated pit;0.00345275428101715!GO:0007059;chromosome segregation;0.00345743010347595!GO:0007052;mitotic spindle organization and biogenesis;0.00355162713093212!GO:0035258;steroid hormone receptor binding;0.00366506962698126!GO:0030036;actin cytoskeleton organization and biogenesis;0.00367199341748949!GO:0030663;COPI coated vesicle membrane;0.00369623802036923!GO:0030126;COPI vesicle coat;0.00369623802036923!GO:0031901;early endosome membrane;0.00369927983527191!GO:0065009;regulation of a molecular function;0.00369985459006818!GO:0016251;general RNA polymerase II transcription factor activity;0.00399088544471271!GO:0003682;chromatin binding;0.00408060379557838!GO:0008092;cytoskeletal protein binding;0.00413367270152909!GO:0006310;DNA recombination;0.00440637917145256!GO:0008139;nuclear localization sequence binding;0.00440921512559217!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00461513254139321!GO:0015002;heme-copper terminal oxidase activity;0.00461513254139321!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00461513254139321!GO:0004129;cytochrome-c oxidase activity;0.00461513254139321!GO:0046467;membrane lipid biosynthetic process;0.00461513254139321!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00463920170701038!GO:0003702;RNA polymerase II transcription factor activity;0.00468503376378231!GO:0032508;DNA duplex unwinding;0.00500423027925358!GO:0032392;DNA geometric change;0.00500423027925358!GO:0042158;lipoprotein biosynthetic process;0.00513879873718798!GO:0051539;4 iron, 4 sulfur cluster binding;0.0051630027865938!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00548270225935108!GO:0000428;DNA-directed RNA polymerase complex;0.00548270225935108!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00556216215376626!GO:0043488;regulation of mRNA stability;0.00556216215376626!GO:0043487;regulation of RNA stability;0.00556216215376626!GO:0016044;membrane organization and biogenesis;0.00556216215376626!GO:0017166;vinculin binding;0.0055832066533039!GO:0008320;protein transmembrane transporter activity;0.00558573138559019!GO:0030137;COPI-coated vesicle;0.00564539163821807!GO:0006650;glycerophospholipid metabolic process;0.00586897659070755!GO:0030118;clathrin coat;0.00599301228258064!GO:0016197;endosome transport;0.00608885138677277!GO:0030660;Golgi-associated vesicle membrane;0.00608885138677277!GO:0000323;lytic vacuole;0.00614107274975556!GO:0005764;lysosome;0.00614107274975556!GO:0022884;macromolecule transmembrane transporter activity;0.00617051212739137!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.00617051212739137!GO:0006405;RNA export from nucleus;0.00623034554508594!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0062380264496291!GO:0045047;protein targeting to ER;0.0062380264496291!GO:0006818;hydrogen transport;0.00624056279147282!GO:0015992;proton transport;0.00629387375421082!GO:0008312;7S RNA binding;0.00635238718678954!GO:0006268;DNA unwinding during replication;0.00641080066820218!GO:0006778;porphyrin metabolic process;0.00696439370772672!GO:0033013;tetrapyrrole metabolic process;0.00696439370772672!GO:0003678;DNA helicase activity;0.00723479789523843!GO:0005876;spindle microtubule;0.00723479789523843!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.00724480126042035!GO:0000339;RNA cap binding;0.0073110254443066!GO:0031982;vesicle;0.00742306809506398!GO:0043022;ribosome binding;0.00750159743598023!GO:0008180;signalosome;0.00775779085513026!GO:0030659;cytoplasmic vesicle membrane;0.00786366250990079!GO:0006611;protein export from nucleus;0.00848075678999057!GO:0009116;nucleoside metabolic process;0.00865354639885809!GO:0006118;electron transport;0.00937084836876907!GO:0006350;transcription;0.00961132745331418!GO:0030027;lamellipodium;0.00972382282451409!GO:0030134;ER to Golgi transport vesicle;0.00980531392019745!GO:0043596;nuclear replication fork;0.00980531392019745!GO:0031410;cytoplasmic vesicle;0.00982030082545637!GO:0000792;heterochromatin;0.00984534901320531!GO:0008168;methyltransferase activity;0.00994414874308498!GO:0031124;mRNA 3'-end processing;0.0100846843904047!GO:0050681;androgen receptor binding;0.0106380375831922!GO:0016741;transferase activity, transferring one-carbon groups;0.0106437071924653!GO:0050662;coenzyme binding;0.0106968855650273!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0107100939434025!GO:0005869;dynactin complex;0.0110432947947915!GO:0030119;AP-type membrane coat adaptor complex;0.0117584918968285!GO:0048487;beta-tubulin binding;0.0120617696367552!GO:0006144;purine base metabolic process;0.0124221998040481!GO:0005832;chaperonin-containing T-complex;0.0127065332489338!GO:0007021;tubulin folding;0.0128698693748467!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0130789366067769!GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;0.0134938452416159!GO:0006378;mRNA polyadenylation;0.0139112295114456!GO:0004527;exonuclease activity;0.0144304496770585!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.0144924230462854!GO:0006733;oxidoreduction coenzyme metabolic process;0.0144933911857511!GO:0006595;polyamine metabolic process;0.0146294863390572!GO:0006213;pyrimidine nucleoside metabolic process;0.0146380588829473!GO:0006740;NADPH regeneration;0.0147059508547806!GO:0006098;pentose-phosphate shunt;0.0147059508547806!GO:0003746;translation elongation factor activity;0.0148978654073259!GO:0042168;heme metabolic process;0.015040189429794!GO:0022890;inorganic cation transmembrane transporter activity;0.015040189429794!GO:0000228;nuclear chromosome;0.015116632303439!GO:0030032;lamellipodium biogenesis;0.0151402974944388!GO:0009303;rRNA transcription;0.0151780466896396!GO:0030029;actin filament-based process;0.0153053362742376!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0154435372023916!GO:0006950;response to stress;0.0156162508061778!GO:0045941;positive regulation of transcription;0.0162871002047682!GO:0005669;transcription factor TFIID complex;0.0163303428391312!GO:0009967;positive regulation of signal transduction;0.01647583651769!GO:0008637;apoptotic mitochondrial changes;0.0167353631861772!GO:0000209;protein polyubiquitination;0.0167353631861772!GO:0008610;lipid biosynthetic process;0.0167353631861772!GO:0030125;clathrin vesicle coat;0.0167913815908984!GO:0030665;clathrin coated vesicle membrane;0.0167913815908984!GO:0030127;COPII vesicle coat;0.0169827326025977!GO:0012507;ER to Golgi transport vesicle membrane;0.0169827326025977!GO:0006509;membrane protein ectodomain proteolysis;0.017469957029216!GO:0033619;membrane protein proteolysis;0.017469957029216!GO:0004674;protein serine/threonine kinase activity;0.0175761165245552!GO:0043624;cellular protein complex disassembly;0.0175761165245552!GO:0019752;carboxylic acid metabolic process;0.0176612987350593!GO:0005862;muscle thin filament tropomyosin;0.0179008668868507!GO:0030133;transport vesicle;0.0179864261659996!GO:0004177;aminopeptidase activity;0.0180875896970349!GO:0005875;microtubule associated complex;0.018194241184259!GO:0030518;steroid hormone receptor signaling pathway;0.018445976514387!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0188706668759556!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0194818344062142!GO:0045892;negative regulation of transcription, DNA-dependent;0.0195364839222479!GO:0004680;casein kinase activity;0.0198333105611542!GO:0045045;secretory pathway;0.0198515738054548!GO:0006275;regulation of DNA replication;0.0202587800605797!GO:0000082;G1/S transition of mitotic cell cycle;0.0203078897219177!GO:0031902;late endosome membrane;0.0209828085587471!GO:0008022;protein C-terminus binding;0.021158592529718!GO:0048144;fibroblast proliferation;0.021158592529718!GO:0048145;regulation of fibroblast proliferation;0.021158592529718!GO:0006779;porphyrin biosynthetic process;0.0211760779157622!GO:0033014;tetrapyrrole biosynthetic process;0.0211760779157622!GO:0006354;RNA elongation;0.0212493950244452!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0215388214745198!GO:0000049;tRNA binding;0.0218758983056092!GO:0046519;sphingoid metabolic process;0.0219647812809134!GO:0046966;thyroid hormone receptor binding;0.0219647812809134!GO:0032200;telomere organization and biogenesis;0.0220655138025158!GO:0000723;telomere maintenance;0.0220655138025158!GO:0006518;peptide metabolic process;0.0222293811947555!GO:0043189;H4/H2A histone acetyltransferase complex;0.0223119170827127!GO:0048146;positive regulation of fibroblast proliferation;0.0229017740931695!GO:0006082;organic acid metabolic process;0.0232263321690921!GO:0007034;vacuolar transport;0.0236064685108692!GO:0031123;RNA 3'-end processing;0.0237531472500266!GO:0032984;macromolecular complex disassembly;0.0237531472500266!GO:0044433;cytoplasmic vesicle part;0.0237531472500266!GO:0030131;clathrin adaptor complex;0.0239668094736758!GO:0016584;nucleosome positioning;0.0239668094736758!GO:0008361;regulation of cell size;0.0244524478555214!GO:0051098;regulation of binding;0.0258003038469387!GO:0045893;positive regulation of transcription, DNA-dependent;0.026148306559995!GO:0019206;nucleoside kinase activity;0.026242851279413!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0263950322919013!GO:0010257;NADH dehydrogenase complex assembly;0.0263950322919013!GO:0033108;mitochondrial respiratory chain complex assembly;0.0263950322919013!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.0264231381890846!GO:0035267;NuA4 histone acetyltransferase complex;0.0266144148602947!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0268549419089797!GO:0043601;nuclear replisome;0.0268549419089797!GO:0030894;replisome;0.0268549419089797!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.026874755681239!GO:0031529;ruffle organization and biogenesis;0.0269055493638699!GO:0031227;intrinsic to endoplasmic reticulum membrane;0.0273536055225774!GO:0043154;negative regulation of caspase activity;0.0280104487798007!GO:0000781;chromosome, telomeric region;0.0281833940082853!GO:0031371;ubiquitin conjugating enzyme complex;0.0283150417237298!GO:0016628;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;0.0287384116357!GO:0000123;histone acetyltransferase complex;0.0290601466017953!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0298912120942294!GO:0016049;cell growth;0.0299803906222221!GO:0006417;regulation of translation;0.0300812889712092!GO:0006376;mRNA splice site selection;0.0300812889712092!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0300812889712092!GO:0006289;nucleotide-excision repair;0.0301517211213585!GO:0005758;mitochondrial intermembrane space;0.030201423785153!GO:0000118;histone deacetylase complex;0.030755362153032!GO:0008632;apoptotic program;0.0310393859011737!GO:0065007;biological regulation;0.0311354335800285!GO:0000070;mitotic sister chromatid segregation;0.0312836188218303!GO:0008017;microtubule binding;0.0315534788584705!GO:0012506;vesicle membrane;0.0315534788584705!GO:0008538;proteasome activator activity;0.0316567648532787!GO:0009119;ribonucleoside metabolic process;0.0320673304589471!GO:0046983;protein dimerization activity;0.0323863102054769!GO:0006767;water-soluble vitamin metabolic process;0.0323977105654479!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.0327819734301753!GO:0008601;protein phosphatase type 2A regulator activity;0.0334865665937293!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0337406301340252!GO:0003923;GPI-anchor transamidase activity;0.0338848986237755!GO:0016255;attachment of GPI anchor to protein;0.0338848986237755!GO:0042765;GPI-anchor transamidase complex;0.0338848986237755!GO:0031625;ubiquitin protein ligase binding;0.0339207280698262!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0342381160586118!GO:0045039;protein import into mitochondrial inner membrane;0.0342381160586118!GO:0006360;transcription from RNA polymerase I promoter;0.0342938703244065!GO:0006892;post-Golgi vesicle-mediated transport;0.034451699191053!GO:0042393;histone binding;0.0346451439554483!GO:0010468;regulation of gene expression;0.0350030635948491!GO:0006672;ceramide metabolic process;0.0354592393554254!GO:0001558;regulation of cell growth;0.0355683931237658!GO:0000725;recombinational repair;0.0356213297778255!GO:0000724;double-strand break repair via homologous recombination;0.0356213297778255!GO:0005732;small nucleolar ribonucleoprotein complex;0.035886951064851!GO:0001726;ruffle;0.036265121334288!GO:0031418;L-ascorbic acid binding;0.036423214584859!GO:0005663;DNA replication factor C complex;0.0368533693804258!GO:0007004;telomere maintenance via telomerase;0.0368856441383143!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0369185770444749!GO:0042769;DNA damage response, detection of DNA damage;0.03718132270625!GO:0000922;spindle pole;0.0373916324048!GO:0031970;organelle envelope lumen;0.0377660093944877!GO:0006739;NADP metabolic process;0.0381008069105887!GO:0022411;cellular component disassembly;0.038312723360383!GO:0006607;NLS-bearing substrate import into nucleus;0.0383874318271338!GO:0030508;thiol-disulfide exchange intermediate activity;0.0386160822572737!GO:0008536;Ran GTPase binding;0.0390514466647291!GO:0016126;sterol biosynthetic process;0.0394074083174292!GO:0043241;protein complex disassembly;0.0394074083174292!GO:0051101;regulation of DNA binding;0.0394074083174292!GO:0000819;sister chromatid segregation;0.0397627699324602!GO:0003857;3-hydroxyacyl-CoA dehydrogenase activity;0.0397757835855999!GO:0008234;cysteine-type peptidase activity;0.0397757835855999!GO:0005744;mitochondrial inner membrane presequence translocase complex;0.0397757835855999!GO:0048468;cell development;0.0401380256268664!GO:0006284;base-excision repair;0.0412563528157515!GO:0022415;viral reproductive process;0.041320409933211!GO:0005652;nuclear lamina;0.0414393512676068!GO:0000790;nuclear chromatin;0.0414419001397568!GO:0005784;translocon complex;0.0415204101345857!GO:0030911;TPR domain binding;0.0418366672990435!GO:0004518;nuclease activity;0.042508400404916!GO:0004532;exoribonuclease activity;0.0425180354950485!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0425180354950485!GO:0050178;phenylpyruvate tautomerase activity;0.042778355256097!GO:0006783;heme biosynthetic process;0.0430972243422718!GO:0000096;sulfur amino acid metabolic process;0.0435064104427309!GO:0030503;regulation of cell redox homeostasis;0.0442046986763953!GO:0022406;membrane docking;0.0442138004791351!GO:0048278;vesicle docking;0.0442138004791351!GO:0006007;glucose catabolic process;0.0447611236158822!GO:0005881;cytoplasmic microtubule;0.044956809377493!GO:0031543;peptidyl-proline dioxygenase activity;0.0459413974702855!GO:0006904;vesicle docking during exocytosis;0.046682346550339!GO:0000726;non-recombinational repair;0.047055970761683!GO:0006914;autophagy;0.0471194437718527!GO:0030865;cortical cytoskeleton organization and biogenesis;0.0471194437718527!GO:0003756;protein disulfide isomerase activity;0.0473711593577609!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0473711593577609!GO:0048037;cofactor binding;0.0474028833024174!GO:0000178;exosome (RNase complex);0.047777323329997!GO:0004003;ATP-dependent DNA helicase activity;0.0480181967178173!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.0489647309891967!GO:0005774;vacuolar membrane;0.0490301568818682!GO:0043631;RNA polyadenylation;0.049418768211393!GO:0006100;tricarboxylic acid cycle intermediate metabolic process;0.0499635489872451
|sample_id=11841
|sample_id=11841
|sample_note=
|sample_note=
Line 76: Line 99:
|sample_tissue=bone marrow
|sample_tissue=bone marrow
|top_motifs=PAX8:1.73901801661;ALX1:1.62949051499;FOXQ1:1.26610144315;HOX{A5,B5}:1.21814442657;ALX4:1.20975265995;PAX4:1.00735172986;NR6A1:0.962560655534;ZBTB16:0.873332111361;LHX3,4:0.804309310324;HOXA9_MEIS1:0.796572472344;NR1H4:0.780790896369;E2F1..5:0.756086698421;ONECUT1,2:0.707460704918;DBP:0.673180063133;POU1F1:0.667448823005;BACH2:0.663428846586;UFEwm:0.648598272183;FOXD3:0.63821344851;AIRE:0.623761871977;HOX{A4,D4}:0.587955858541;NKX3-1:0.568123609586;ADNP_IRX_SIX_ZHX:0.54033928455;RFX1:0.532353300333;MYB:0.515475345926;NFE2L2:0.499721855291;STAT1,3:0.493385256088;EVI1:0.482576091829;FOX{I1,J2}:0.473940323016;POU2F1..3:0.433006042772;GCM1,2:0.353825991763;POU3F1..4:0.32243185435;FOXL1:0.321285481889;ZNF143:0.305692760104;FOS_FOS{B,L1}_JUN{B,D}:0.294589054493;FOSL2:0.282669046853;TEF:0.27494582656;HNF1A:0.250437442148;ARID5B:0.237827563491;NFIL3:0.234593568466;IKZF2:0.219531591441;PRRX1,2:0.217587280507;NKX3-2:0.208112667646;NFE2:0.198845224182;GFI1:0.194473378573;NR3C1:0.179174249644;XCPE1{core}:0.15524515372;NFE2L1:0.152367086567;STAT5{A,B}:0.147512408144;TBP:0.131891391783;POU5F1:0.131829592922;T:0.127662185173;NFY{A,B,C}:0.123622225005;RFX2..5_RFXANK_RFXAP:0.109718577823;SMAD1..7,9:0.109170496484;NRF1:0.0993927470136;SOX2:0.0865715315309;CDC5L:0.069640628356;PBX1:0.0691130592137;TEAD1:0.0600886790667;TFDP1:0.0540113428517;MYOD1:0.0431008932328;TLX1..3_NFIC{dimer}:-0.0177530526175;ZIC1..3:-0.0183127248505;OCT4_SOX2{dimer}:-0.0208380387995;PITX1..3:-0.0233049142112;HES1:-0.0280996158722;GFI1B:-0.0281169240267;ZNF384:-0.0402464580062;CUX2:-0.0455561990988;STAT2,4,6:-0.0651645961775;HSF1,2:-0.0693742676963;EN1,2:-0.0698278798478;PAX3,7:-0.0923735404155;CDX1,2,4:-0.0957713423659;ZNF148:-0.100361771242;RXRA_VDR{dimer}:-0.103740342979;AR:-0.108124416508;ZNF238:-0.110304923903;TP53:-0.119220295029;ZEB1:-0.12492742443;FOXP3:-0.144376897523;NKX2-3_NKX2-5:-0.171680448343;SOX{8,9,10}:-0.176154934551;TBX4,5:-0.179863170097;HNF4A_NR2F1,2:-0.180487775413;IKZF1:-0.185577950295;XBP1:-0.19311386938;PAX6:-0.198144498553;ZBTB6:-0.211347924311;GTF2A1,2:-0.225427500234;ZFP161:-0.229349373201;YY1:-0.243732975137;NFKB1_REL_RELA:-0.248070927988;BREu{core}:-0.250861725552;PDX1:-0.252249672236;VSX1,2:-0.253938311874;ELK1,4_GABP{A,B1}:-0.256092857198;NR5A1,2:-0.256681979401;MYBL2:-0.263934435621;LEF1_TCF7_TCF7L1,2:-0.26709940999;SOX17:-0.272153812394;DMAP1_NCOR{1,2}_SMARC:-0.278543749614;GATA6:-0.281595055573;PPARG:-0.288905587233;HAND1,2:-0.291715037117;NANOG:-0.295132097142;NKX6-1,2:-0.305390522224;PAX1,9:-0.30959896824;HMX1:-0.319501802023;SNAI1..3:-0.328911302784;RUNX1..3:-0.362189633865;HIC1:-0.36914398029;NHLH1,2:-0.371333742511;HLF:-0.37404948954;POU6F1:-0.386489958952;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.398576379339;FOX{F1,F2,J1}:-0.406522813958;LMO2:-0.429675244235;ETS1,2:-0.431707589255;SPIB:-0.433525176784;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.437676573749;ELF1,2,4:-0.441497308045;EP300:-0.442157899982;GTF2I:-0.443956791316;MEF2{A,B,C,D}:-0.447752044194;bHLH_family:-0.45087535845;NANOG{mouse}:-0.451539917811;NKX2-1,4:-0.45339226756;FOXN1:-0.463142647711;AHR_ARNT_ARNT2:-0.475237628009;RORA:-0.480941166192;TAL1_TCF{3,4,12}:-0.486697587134;TFCP2:-0.494586797873;CREB1:-0.495771859847;MZF1:-0.503745609141;HMGA1,2:-0.504082254364;ATF5_CREB3:-0.506626905363;JUN:-0.515329472402;MYFfamily:-0.53524934921;HBP1_HMGB_SSRP1_UBTF:-0.539178278155;KLF4:-0.541184169973;PAX2:-0.548894622886;ESRRA:-0.556463610611;BPTF:-0.557048524651;GZF1:-0.561871246807;MED-1{core}:-0.584667213882;REST:-0.587818801792;SPI1:-0.604231099189;MTE{core}:-0.604731578918;NFATC1..3:-0.610981325656;IRF7:-0.615281616964;TOPORS:-0.618091590239;CEBPA,B_DDIT3:-0.647383693354;EBF1:-0.656235027942;PRDM1:-0.657868341975;TFAP4:-0.658797969846;SRF:-0.672176873004;SPZ1:-0.672369363371;FOXA2:-0.688647124086;RBPJ:-0.691072569684;NKX2-2,8:-0.704736600528;FOXM1:-0.706340360555;PAX5:-0.72871352303;ATF4:-0.745413071305;FOXP1:-0.75165371396;GATA4:-0.753758000311;EGR1..3:-0.777711186252;CRX:-0.779381270682;GLI1..3:-0.795519649807;IRF1,2:-0.796193492351;SP1:-0.806348075662;NFIX:-0.816692535203;RXR{A,B,G}:-0.833028401264;TFAP2B:-0.867057871204;SOX5:-0.878063992861;ZNF423:-0.903734464625;ATF6:-0.935528811931;MAZ:-0.94766324468;RREB1:-0.951917628102;HIF1A:-1.02715363858;ESR1:-1.05562779264;ATF2:-1.1165507393;TFAP2{A,C}:-1.13264301498;TLX2:-1.20105992107;MTF1:-1.23124082766;FOX{D1,D2}:-1.26263733195;HOX{A6,A7,B6,B7}:-1.27529330368;MAFB:-1.30406479291;TGIF1:-1.44507195908;PATZ1:-1.51431524149;SREBF1,2:-1.63761978356;FOXO1,3,4:-2.09140797006
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|xref=
}}
}}

Revision as of 21:19, 10 August 2017

Name:serous adenocarcinoma cell line:SK-OV-3-R, biol_rep1
Species:Human (Homo sapiens)
Library ID:CNhs13099
Sample type:cell lines
Genomic View: UCSC
RefEX:Specific genes
CAGEd-oPOSSUM:link
Additional information
Sample information
strainNA
tissuebone marrow
dev stageNA
sexNA
ageNA
cell typemesenchymal precursor cell
cell lineNA
companyNA
collaborationClaudio Schneider LNCIB
External link for information[{{{sample_info_link}}} {{{sample_info_link}}}]
RNA information
lot numberNA
catalog numberNA
sample typetotal RNA
extraction protocol (Details)OP-RNA-extraction-totalRNA-TRIzol-ethanol-v1.0

CAGE Accession numbers
MethodSample accession id
CAGE  SAMD00005412
Library accession numbers

Library idMethodExp. accession idRun accession id
CNhs13099 CAGE DRX008000 DRR008872
Accession ID Hg19

Library idBAMCTSS
CNhs13099 DRZ000297 DRZ001682
Accession ID Hg38

Library idBAMCTSS
CNhs13099 DRZ011647 DRZ013032
Download raw sequence, BAM & CTSS
Hg19
FastaBAMCTSS
downloaddownloaddonwload
Hg38
BAMCTSS
downloaddonwload


Relative expression to median (log10)


Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.



Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data

Coexpression clusterscore
C0-CD14-Eosinophils-Neutrophils-Basophils-CD34-immature-Peripheral0
C1-testis-epididymis-embryonic-medulla-pituitary-trachea-caudate0
C10-occipital-temporal-parietal-brain-duodenum-Neurons-Neural0
C100-rhabdomyosarcoma-gastric-pineal-Wilms-cervical-mesodermal-endometrial0
C101-small-cerebellum-maxillary-colon-parietal-epididymis-merkel0
C102-neuroblastoma-testicular-pituitary-carcinosarcoma-rectum-acantholytic-iPS0
C103-CD4-CD8-Natural-Peripheral-Whole-Neutrophils-Basophils0
C104-Mast-Basophils-immature-CD14-CD34-eye-Natural0
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C88-Melanocyte-melanoma-Macrophage-Mesenchymal-migratory-Dendritic-Monocytederived0
C89-small-retinoblastoma-medulloblastoma-iPS-acantholytic-eye-bronchogenic0
C9-skeletal-diaphragm-tongue-throat-penis-heart-left0
C90-neuroectodermal-peripheral-neuroepithelioma-neuroblastoma-carcinoid-parietal-putamen0
C91-Fibroblast-Smooth-mesenchymal-Mesothelial-Small-Preadipocyte-Hair0
C92-CD14CD16-CD14-Eosinophils-Basophils-Neutrophils-Macrophage-Whole0
C93-chronic-acute-leukemia-acantholytic-medulloblastoma-testis-papillotubular0
C94-smallcell-adrenal-lung-nonsmall-small-somatostatinoma-teratocarcinoma0
C95-lung-aorta-trachea-penis-Alveolar-throat-endometrioid0
C96-non-acute-tonsil-spleen-Burkitt-lymphoma-appendix0
C97-small-smallcell-gastrointestinal-argyrophil-putamen-duodenum-brain0
C98-CD8-Natural-Basophils-blood-CD4-Peripheral-Whole0
C99-hairy-mycosis-submaxillary-salivary-cord-kidney-parotid0



Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data



TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample


JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs13099

Jaspar motifP-value
MA0002.20.199
MA0003.10.138
MA0004.10.548
MA0006.10.274
MA0007.10.0327
MA0009.10.938
MA0014.10.0434
MA0017.10.463
MA0018.20.00573
MA0019.10.849
MA0024.10.257
MA0025.10.264
MA0027.10.639
MA0028.10.791
MA0029.10.385
MA0030.10.0994
MA0031.10.357
MA0035.20.874
MA0038.10.811
MA0039.20.196
MA0040.10.468
MA0041.10.646
MA0042.10.875
MA0043.13.49847e-4
MA0046.10.158
MA0047.20.259
MA0048.10.524
MA0050.12.29659e-6
MA0051.10.0152
MA0052.10.00985
MA0055.10.261
MA0057.10.432
MA0058.10.193
MA0059.10.243
MA0060.10.00196
MA0061.10.459
MA0062.20.465
MA0065.20.0594
MA0066.10.111
MA0067.10.0154
MA0068.15.65768e-4
MA0069.10.792
MA0070.10.934
MA0071.10.31
MA0072.10.676
MA0073.10.482
MA0074.10.328
MA0076.10.446
MA0077.10.3
MA0078.10.221
MA0079.20.159
MA0080.28.18792e-5
MA0081.10.0511
MA0083.10.852
MA0084.10.917
MA0087.10.245
MA0088.10.0128
MA0090.10.829
MA0091.10.963
MA0092.10.509
MA0093.10.418
MA0099.23.76571e-13
MA0100.10.256
MA0101.10.5
MA0102.20.0651
MA0103.10.273
MA0104.20.922
MA0105.12.96607e-5
MA0106.10.0696
MA0107.10.63
MA0108.20.411
MA0111.10.348
MA0112.20.0121
MA0113.10.723
MA0114.10.325
MA0115.10.723
MA0116.13.89612e-4
MA0117.10.555
MA0119.10.0218
MA0122.10.72
MA0124.10.479
MA0125.10.758
MA0131.10.683
MA0135.10.154
MA0136.19.4705e-4
MA0137.20.877
MA0138.20.375
MA0139.10.236
MA0140.10.915
MA0141.10.0198
MA0142.10.284
MA0143.10.42
MA0144.10.621
MA0145.10.485
MA0146.10.948
MA0147.10.401
MA0148.10.841
MA0149.10.0206
MA0150.10.0388
MA0152.10.0724
MA0153.10.0916
MA0154.10.0753
MA0155.10.908
MA0156.10.0192
MA0157.10.914
MA0159.10.0911
MA0160.10.366
MA0162.10.127
MA0163.10.00218
MA0164.10.785
MA0258.10.0601
MA0259.10.236



FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs13099

Novel motifP-value
10.00923
100.109
1000.0303
1010.385
1020.845
1030.157
1040.735
1050.783
1060.427
1070.572
1080.659
1090.0663
110.126
1100.239
1110.358
1120.229
1130.421
1140.158
1150.646
1160.552
1170.137
1180.54
1190.334
120.627
1200.0527
1210.479
1220.9
1231
1240.0128
1250.113
1260.672
1270.521
1280.86
1290.317
130.106
1300.827
1310.249
1320.14
1330.0176
1340.544
1350.084
1360.64
1370.811
1380.337
1390.843
140.906
1400.184
1410.155
1420.678
1430.00472
1440.529
1450.57
1460.832
1470.151
1480.421
1490.433
150.0144
1500.538
1510.564
1520.316
1530.87
1540.998
1550.687
1560.0388
1570.593
1580.376
1590.252
160.109
1600.156
1610.604
1620.37
1630.484
1640.231
1650.696
1660.563
1670.0511
1680.749
1690.097
170.633
180.1
190.563
20.806
200.91
210.918
220.665
230.317
240.213
250.27
260.0193
270.507
280.929
290.11
30.13
300.947
310.864
320.924
330.0152
340.176
350.388
360.0223
370.164
380.411
390.686
40.144
400.027
410.849
420.176
430.176
440.0805
450.717
460.021
470.132
480.142
490.103
50.168
500.881
510.682
520.818
530.629
540.88
550.581
560.32
570.172
580.815
590.374
60.656
600.522
610.366
620.278
630.352
640.114
650.818
661.66553e-4
670.612
680.712
690.408
70.21
700.525
710.0558
720.988
730.871
740.397
750.23
760.611
770.378
780.453
790.826
80.0187
800.947
810.172
820.351
830.0303
840.618
850.45
860.359
870.239
880.785
890.2
90.991
900.516
910.317
920.794
930.407
940.0308
950.714
960.57
970.792
980.162
990.312



de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br> library id: CNhs13099


FANTOM5 (FF) ontology


Direct parent terms


Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data

CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0002320 (connective tissue cell)
0000066 (epithelial cell)
0002371 (somatic cell)
0000499 (stromal cell)
0000255 (eukaryotic cell)
0002076 (endo-epithelial cell)
0002149 (epithelial cell of uterus)
0002255 (stromal cell of endometrium)

DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
14566 (disease of cellular proliferation)
0050687 (cell type cancer)
193 (reproductive organ cancer)
305 (carcinoma)
120 (female reproductive organ cancer)
299 (adenocarcinoma)
3001 (female reproductive endometrioid cancer)

UBERON: Anatomy
0000468 (multi-cellular organism)
0000995 (uterus)
0002384 (connective tissue)
0003134 (female reproductive organ)
0000479 (tissue)
0005156 (reproductive structure)
0000062 (organ)
0004120 (mesoderm-derived structure)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000990 (reproductive system)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0003133 (reproductive organ)
0003975 (internal female genitalia)
0004175 (internal genitalia)
0010317 (germ layer / neural crest derived structure)
0003100 (female organism)
0000474 (female reproductive system)

FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0103803 (serous adenocarcinoma cell line sample)
0100297 (carcinoma cell line sample)
0101120 (epithelial cell line sample)
0100167 (adenocarcinoma cell line sample)
0100658 (uterine adenocarcinoma cell sample)
0101555 (endometrial cancer cell line sample)

Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)
CL:0000223 (endodermal cell)
UBERON:0002532 (epiblast (generic))
UBERON:0006603 (presumptive mesoderm)
UBERON:0005795 (embryonic uterus)
UBERON:0010316 (germ layer / neural crest)