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{{f5samples
{{f5samples
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|comment=A2  T0
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|fonse_treatment_closure=EFO:0000369,FF:0000332,FF:0000593,FF:12760-136B6
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|id=FF:12760-136B6
|id=FF:12760-136B6
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|name=Saos-2 osteosarcoma treated with ascorbic acid and BGP to induce calcification, 00hr00min, biol_rep2 (A2 T0)
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|name=Saos-2 osteosarcoma treated with ascorbic acid and BGP to induce calcification
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|rna_box=136
|rna_box=136
|rna_catalog_number=
|rna_catalog_number=
Line 56: Line 82:
|rna_tube_id=136B6
|rna_tube_id=136B6
|rna_weight_ug=10.87
|rna_weight_ug=10.87
|rnaseq_library_id=SRhi10065.GTGGCC
|sample_age=
|sample_age=
|sample_category=time courses
|sample_cell_catalog=
|sample_cell_catalog=
|sample_cell_line=Saos-2
|sample_cell_line=Saos-2
Line 69: Line 97:
|sample_ethnicity=
|sample_ethnicity=
|sample_experimental_condition=Saos-2 osteosarcoma treated with ascorbic acid and BGP to induce calcification
|sample_experimental_condition=Saos-2 osteosarcoma treated with ascorbic acid and BGP to induce calcification
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;3.28694854971549e-289!GO:0043226;organelle;4.55799438036546e-247!GO:0043229;intracellular organelle;1.51910849448168e-246!GO:0043231;intracellular membrane-bound organelle;1.540327395663e-243!GO:0043227;membrane-bound organelle;1.540327395663e-243!GO:0005737;cytoplasm;5.97455140668863e-169!GO:0044422;organelle part;2.02082234488925e-166!GO:0044446;intracellular organelle part;9.2919371132238e-165!GO:0005634;nucleus;3.18514691800628e-130!GO:0032991;macromolecular complex;2.43051316862708e-116!GO:0044444;cytoplasmic part;2.53376665628659e-111!GO:0044238;primary metabolic process;5.77511957358522e-110!GO:0044237;cellular metabolic process;8.47586104293998e-108!GO:0043170;macromolecule metabolic process;1.14222502357186e-106!GO:0044428;nuclear part;1.48948710950534e-92!GO:0030529;ribonucleoprotein complex;1.4934947369715e-88!GO:0043233;organelle lumen;4.46312781104785e-82!GO:0031974;membrane-enclosed lumen;4.46312781104785e-82!GO:0005515;protein binding;1.52915125167532e-79!GO:0003723;RNA binding;1.74147471337705e-79!GO:0043283;biopolymer metabolic process;4.65607516866328e-77!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.60848852208944e-70!GO:0010467;gene expression;8.65529582359981e-65!GO:0016043;cellular component organization and biogenesis;3.59886917512644e-62!GO:0043234;protein complex;2.00853304322572e-61!GO:0005739;mitochondrion;1.76139743535489e-60!GO:0006396;RNA processing;2.7742703581868e-57!GO:0031981;nuclear lumen;6.27610248792197e-55!GO:0005840;ribosome;1.70604964936301e-49!GO:0003676;nucleic acid binding;5.04149021080839e-49!GO:0031090;organelle membrane;3.62808577933967e-47!GO:0043228;non-membrane-bound organelle;8.8203711621096e-47!GO:0043232;intracellular non-membrane-bound organelle;8.8203711621096e-47!GO:0006412;translation;1.43631643636517e-46!GO:0006259;DNA metabolic process;3.63203434367302e-46!GO:0016071;mRNA metabolic process;4.50099320316619e-45!GO:0006996;organelle organization and biogenesis;1.33576330682121e-44!GO:0031967;organelle envelope;1.61865512841243e-43!GO:0044429;mitochondrial part;2.01959798629044e-43!GO:0031975;envelope;3.15299395919372e-43!GO:0003735;structural constituent of ribosome;5.60960820193793e-43!GO:0019538;protein metabolic process;1.30341333093444e-41!GO:0033036;macromolecule localization;3.45365358937381e-41!GO:0008380;RNA splicing;3.49873318457093e-41!GO:0015031;protein transport;1.8251850511993e-40!GO:0046907;intracellular transport;8.11827030727768e-40!GO:0006397;mRNA processing;3.65080145917402e-39!GO:0007049;cell cycle;9.85133074277446e-39!GO:0016070;RNA metabolic process;2.90285952062406e-37!GO:0044260;cellular macromolecule metabolic process;5.93627817593588e-37!GO:0008104;protein localization;9.48423761769523e-37!GO:0065003;macromolecular complex assembly;1.51009753520195e-36!GO:0005654;nucleoplasm;2.38156150220733e-36!GO:0044267;cellular protein metabolic process;5.22172150098194e-36!GO:0033279;ribosomal subunit;1.11706240480883e-35!GO:0045184;establishment of protein localization;1.23947734380328e-35!GO:0044249;cellular biosynthetic process;7.34952866050993e-35!GO:0009058;biosynthetic process;2.70955478161496e-34!GO:0009059;macromolecule biosynthetic process;1.38923558985738e-33!GO:0005829;cytosol;5.51285386636798e-32!GO:0022613;ribonucleoprotein complex biogenesis and assembly;6.79202743665389e-32!GO:0022607;cellular component assembly;7.77941342917352e-32!GO:0000166;nucleotide binding;4.39703138834241e-31!GO:0006886;intracellular protein transport;5.14151712064538e-31!GO:0005694;chromosome;1.86009596917789e-29!GO:0044451;nucleoplasm part;3.05927900586139e-29!GO:0005681;spliceosome;3.32749162896498e-29!GO:0005740;mitochondrial envelope;1.24527532968341e-28!GO:0022402;cell cycle process;4.18282068168511e-28!GO:0031966;mitochondrial membrane;1.64223729799826e-27!GO:0000278;mitotic cell cycle;3.07440743144052e-27!GO:0019866;organelle inner membrane;8.6849185992983e-27!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.71090104089194e-26!GO:0051649;establishment of cellular localization;6.32521126008145e-26!GO:0044427;chromosomal part;1.57167435082967e-25!GO:0051641;cellular localization;1.71975444865858e-25!GO:0006974;response to DNA damage stimulus;3.21234722040044e-25!GO:0005743;mitochondrial inner membrane;4.28450806677266e-24!GO:0051276;chromosome organization and biogenesis;1.57280653716184e-23!GO:0016462;pyrophosphatase activity;1.86790223782093e-23!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;1.96489670396804e-23!GO:0016817;hydrolase activity, acting on acid anhydrides;2.68672807150096e-23!GO:0022403;cell cycle phase;8.58659534832165e-23!GO:0017111;nucleoside-triphosphatase activity;1.06772424459817e-22!GO:0032553;ribonucleotide binding;1.93170224840816e-22!GO:0032555;purine ribonucleotide binding;1.93170224840816e-22!GO:0006512;ubiquitin cycle;3.71325323538782e-22!GO:0006281;DNA repair;3.77379818814485e-22!GO:0000087;M phase of mitotic cell cycle;1.15941847500156e-21!GO:0007067;mitosis;1.88733444099507e-21!GO:0051301;cell division;2.6521076986977e-21!GO:0017076;purine nucleotide binding;4.62160170451529e-21!GO:0006119;oxidative phosphorylation;9.30675484978087e-21!GO:0044445;cytosolic part;1.26001299469652e-20!GO:0016874;ligase activity;1.39539439241131e-20!GO:0044455;mitochondrial membrane part;2.77844527694538e-20!GO:0005524;ATP binding;7.43169924718948e-20!GO:0051603;proteolysis involved in cellular protein catabolic process;7.59009691122394e-20!GO:0032559;adenyl ribonucleotide binding;1.24213618981377e-19!GO:0019941;modification-dependent protein catabolic process;1.42632331335903e-19!GO:0043632;modification-dependent macromolecule catabolic process;1.42632331335903e-19!GO:0044257;cellular protein catabolic process;3.37065557828667e-19!GO:0012505;endomembrane system;3.42360788180526e-19!GO:0006511;ubiquitin-dependent protein catabolic process;3.42431227980293e-19!GO:0006260;DNA replication;4.14526633076943e-19!GO:0000279;M phase;7.56897136998941e-19!GO:0044265;cellular macromolecule catabolic process;8.91351197690225e-19!GO:0015935;small ribosomal subunit;1.1647638952784e-18!GO:0006325;establishment and/or maintenance of chromatin architecture;2.27614952073356e-18!GO:0022618;protein-RNA complex assembly;3.43807216747644e-18!GO:0015934;large ribosomal subunit;3.5936179037724e-18!GO:0030554;adenyl nucleotide binding;4.8932890897999e-18!GO:0005730;nucleolus;5.5903262032497e-18!GO:0006323;DNA packaging;1.15691738787962e-17!GO:0031980;mitochondrial lumen;1.26680592981436e-17!GO:0005759;mitochondrial matrix;1.26680592981436e-17!GO:0043285;biopolymer catabolic process;1.68230441959073e-17!GO:0006457;protein folding;4.02544886960225e-17!GO:0008134;transcription factor binding;5.12983405927795e-17!GO:0006605;protein targeting;1.28136025814414e-16!GO:0031965;nuclear membrane;1.65778663635559e-16!GO:0000502;proteasome complex (sensu Eukaryota);2.14806259145997e-16!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;2.45743128496523e-16!GO:0005746;mitochondrial respiratory chain;3.14221497500521e-16!GO:0008135;translation factor activity, nucleic acid binding;3.22378945208601e-16!GO:0009719;response to endogenous stimulus;3.31949423115792e-16!GO:0048770;pigment granule;6.77536468935606e-16!GO:0042470;melanosome;6.77536468935606e-16!GO:0000398;nuclear mRNA splicing, via spliceosome;9.02243364053677e-16!GO:0000375;RNA splicing, via transesterification reactions;9.02243364053677e-16!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;9.02243364053677e-16!GO:0005635;nuclear envelope;1.69652650487683e-15!GO:0009057;macromolecule catabolic process;1.72457172840029e-15!GO:0030163;protein catabolic process;1.94087149387666e-15!GO:0050136;NADH dehydrogenase (quinone) activity;2.75100667744017e-15!GO:0003954;NADH dehydrogenase activity;2.75100667744017e-15!GO:0008137;NADH dehydrogenase (ubiquinone) activity;2.75100667744017e-15!GO:0043412;biopolymer modification;8.93174860047254e-15!GO:0042254;ribosome biogenesis and assembly;1.20779909300506e-14!GO:0016604;nuclear body;1.39584263476954e-14!GO:0044453;nuclear membrane part;1.54375358793344e-14!GO:0016887;ATPase activity;3.22850774935061e-14!GO:0005783;endoplasmic reticulum;4.19894183212463e-14!GO:0006913;nucleocytoplasmic transport;4.2676027051242e-14!GO:0015630;microtubule cytoskeleton;4.31268632901896e-14!GO:0048193;Golgi vesicle transport;5.23084587316966e-14!GO:0044248;cellular catabolic process;6.1121850494293e-14!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);6.8474436766998e-14!GO:0050794;regulation of cellular process;8.45890253586517e-14!GO:0006333;chromatin assembly or disassembly;1.1295644517657e-13!GO:0051169;nuclear transport;1.36605859100105e-13!GO:0000074;regulation of progression through cell cycle;1.47519210438022e-13!GO:0051726;regulation of cell cycle;1.6037292548523e-13!GO:0000785;chromatin;1.6931461718553e-13!GO:0042623;ATPase activity, coupled;2.43595584813202e-13!GO:0044432;endoplasmic reticulum part;3.54998712173949e-13!GO:0005761;mitochondrial ribosome;3.92203400245416e-13!GO:0000313;organellar ribosome;3.92203400245416e-13!GO:0030964;NADH dehydrogenase complex (quinone);4.0914525642437e-13!GO:0045271;respiratory chain complex I;4.0914525642437e-13!GO:0005747;mitochondrial respiratory chain complex I;4.0914525642437e-13!GO:0042775;organelle ATP synthesis coupled electron transport;5.01720203382082e-13!GO:0042773;ATP synthesis coupled electron transport;5.01720203382082e-13!GO:0006464;protein modification process;6.26636824984645e-13!GO:0006366;transcription from RNA polymerase II promoter;6.45107331853773e-13!GO:0004386;helicase activity;6.74583408590786e-13!GO:0019222;regulation of metabolic process;7.31642652428053e-13!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);8.24503487626087e-13!GO:0005794;Golgi apparatus;9.56959072386128e-13!GO:0065004;protein-DNA complex assembly;9.829563260163e-13!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;1.21749693813153e-12!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.82315182809111e-12!GO:0051186;cofactor metabolic process;2.05704436356866e-12!GO:0043687;post-translational protein modification;2.1832127844012e-12!GO:0051082;unfolded protein binding;2.36267884584308e-12!GO:0005643;nuclear pore;4.24865829004457e-12!GO:0050657;nucleic acid transport;4.78646371046261e-12!GO:0051236;establishment of RNA localization;4.78646371046261e-12!GO:0050658;RNA transport;4.78646371046261e-12!GO:0006403;RNA localization;5.44460700847652e-12!GO:0003743;translation initiation factor activity;1.05360139130574e-11!GO:0006399;tRNA metabolic process;1.12860801815745e-11!GO:0000775;chromosome, pericentric region;1.31017954995919e-11!GO:0016568;chromatin modification;1.45621632730531e-11!GO:0016607;nuclear speck;2.11624095362214e-11!GO:0016192;vesicle-mediated transport;3.71030695457219e-11!GO:0006261;DNA-dependent DNA replication;4.0589669147499e-11!GO:0008639;small protein conjugating enzyme activity;5.17798940044533e-11!GO:0065002;intracellular protein transport across a membrane;5.58832208499218e-11!GO:0008026;ATP-dependent helicase activity;8.87758793123053e-11!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.50878673316495e-10!GO:0004842;ubiquitin-protein ligase activity;1.54839567496786e-10!GO:0017038;protein import;1.95647297123487e-10!GO:0006413;translational initiation;2.0702342631548e-10!GO:0016879;ligase activity, forming carbon-nitrogen bonds;2.69783872727777e-10!GO:0006350;transcription;3.03183280968166e-10!GO:0006364;rRNA processing;3.24369415450391e-10!GO:0031323;regulation of cellular metabolic process;4.18099360552459e-10!GO:0005819;spindle;4.6419545583612e-10!GO:0006732;coenzyme metabolic process;5.3641425538899e-10!GO:0051028;mRNA transport;5.68682441256881e-10!GO:0019787;small conjugating protein ligase activity;6.51501691794872e-10!GO:0003712;transcription cofactor activity;7.06950973145364e-10!GO:0006461;protein complex assembly;7.45560562585253e-10!GO:0006446;regulation of translational initiation;9.15230240831447e-10!GO:0046930;pore complex;9.42848165591729e-10!GO:0016072;rRNA metabolic process;1.0593102890603e-09!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.1578929310767e-09!GO:0006334;nucleosome assembly;1.34369974278833e-09!GO:0030532;small nuclear ribonucleoprotein complex;1.46717239680413e-09!GO:0031497;chromatin assembly;1.99545395706887e-09!GO:0016881;acid-amino acid ligase activity;2.00108573148198e-09!GO:0009055;electron carrier activity;2.27730540377647e-09!GO:0008565;protein transporter activity;2.55823444384195e-09!GO:0003697;single-stranded DNA binding;2.9168035364368e-09!GO:0050789;regulation of biological process;2.95140318620169e-09!GO:0005789;endoplasmic reticulum membrane;3.24678198190578e-09!GO:0005667;transcription factor complex;4.11682269962031e-09!GO:0051329;interphase of mitotic cell cycle;4.18392128125119e-09!GO:0006163;purine nucleotide metabolic process;4.41062075711104e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;4.57794533710451e-09!GO:0009259;ribonucleotide metabolic process;4.93202498685794e-09!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;6.5772467547516e-09!GO:0004812;aminoacyl-tRNA ligase activity;6.5772467547516e-09!GO:0016875;ligase activity, forming carbon-oxygen bonds;6.5772467547516e-09!GO:0043566;structure-specific DNA binding;1.02175851516045e-08!GO:0005793;ER-Golgi intermediate compartment;1.46894743839349e-08!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.61935446195371e-08!GO:0005813;centrosome;1.68230755504949e-08!GO:0051325;interphase;1.89972753205835e-08!GO:0000075;cell cycle checkpoint;2.2979851105016e-08!GO:0031324;negative regulation of cellular metabolic process;2.2979851105016e-08!GO:0043038;amino acid activation;2.42320941333034e-08!GO:0006418;tRNA aminoacylation for protein translation;2.42320941333034e-08!GO:0043039;tRNA aminoacylation;2.42320941333034e-08!GO:0032446;protein modification by small protein conjugation;2.4713333793727e-08!GO:0009150;purine ribonucleotide metabolic process;3.36723916442769e-08!GO:0016567;protein ubiquitination;3.44852017166371e-08!GO:0010468;regulation of gene expression;3.44852017166371e-08!GO:0016740;transferase activity;3.67921623597495e-08!GO:0006164;purine nucleotide biosynthetic process;3.68167610571826e-08!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;4.15841748684294e-08!GO:0005815;microtubule organizing center;4.84989934974475e-08!GO:0032774;RNA biosynthetic process;4.97284536729921e-08!GO:0007051;spindle organization and biogenesis;5.71223022686257e-08!GO:0051170;nuclear import;5.73554079878612e-08!GO:0016779;nucleotidyltransferase activity;6.71654744735602e-08!GO:0006351;transcription, DNA-dependent;7.69387012393987e-08!GO:0048523;negative regulation of cellular process;7.70225869744334e-08!GO:0009260;ribonucleotide biosynthetic process;8.00057845546978e-08!GO:0009141;nucleoside triphosphate metabolic process;9.67707955270681e-08!GO:0003677;DNA binding;9.75449051160509e-08!GO:0006606;protein import into nucleus;1.06750687170581e-07!GO:0009199;ribonucleoside triphosphate metabolic process;1.28148797704264e-07!GO:0000245;spliceosome assembly;1.33027486736404e-07!GO:0009060;aerobic respiration;1.40333669640351e-07!GO:0012501;programmed cell death;1.74929546325518e-07!GO:0048475;coated membrane;1.93956905105364e-07!GO:0030117;membrane coat;1.93956905105364e-07!GO:0006888;ER to Golgi vesicle-mediated transport;2.39864876438801e-07!GO:0003682;chromatin binding;2.39864876438801e-07!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.44582903857802e-07!GO:0006915;apoptosis;2.48041163735461e-07!GO:0015986;ATP synthesis coupled proton transport;2.56182332566992e-07!GO:0015985;energy coupled proton transport, down electrochemical gradient;2.56182332566992e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;2.58093564311209e-07!GO:0009144;purine nucleoside triphosphate metabolic process;2.58093564311209e-07!GO:0009152;purine ribonucleotide biosynthetic process;2.75781189349039e-07!GO:0000151;ubiquitin ligase complex;3.1887308741062e-07!GO:0046034;ATP metabolic process;3.20340687165145e-07!GO:0009056;catabolic process;3.29094359197512e-07!GO:0009892;negative regulation of metabolic process;3.35747049059914e-07!GO:0030120;vesicle coat;3.65935967375506e-07!GO:0030662;coated vesicle membrane;3.65935967375506e-07!GO:0005657;replication fork;4.07572450456211e-07!GO:0044431;Golgi apparatus part;5.0143611069889e-07!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;5.5578936928606e-07!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;5.66106218612316e-07!GO:0045786;negative regulation of progression through cell cycle;6.88621809302342e-07!GO:0016772;transferase activity, transferring phosphorus-containing groups;7.16547510283133e-07!GO:0045333;cellular respiration;7.60743698911481e-07!GO:0031202;RNA splicing factor activity, transesterification mechanism;8.2347839513164e-07!GO:0003924;GTPase activity;8.62435622979438e-07!GO:0045449;regulation of transcription;8.84977994277027e-07!GO:0005874;microtubule;1.10652129770367e-06!GO:0009142;nucleoside triphosphate biosynthetic process;1.15654876568647e-06!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.15654876568647e-06!GO:0006793;phosphorus metabolic process;1.17523563265173e-06!GO:0006796;phosphate metabolic process;1.17523563265173e-06!GO:0019829;cation-transporting ATPase activity;1.26595739698235e-06!GO:0051188;cofactor biosynthetic process;1.55658198640809e-06!GO:0008219;cell death;1.62734650305368e-06!GO:0016265;death;1.62734650305368e-06!GO:0045259;proton-transporting ATP synthase complex;1.70142344803987e-06!GO:0008094;DNA-dependent ATPase activity;1.71849906328542e-06!GO:0007005;mitochondrion organization and biogenesis;1.73838230675445e-06!GO:0005839;proteasome core complex (sensu Eukaryota);2.08066214847613e-06!GO:0006099;tricarboxylic acid cycle;2.13496946590705e-06!GO:0046356;acetyl-CoA catabolic process;2.13496946590705e-06!GO:0043623;cellular protein complex assembly;2.23714493598405e-06!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;2.33802834324656e-06!GO:0009145;purine nucleoside triphosphate biosynthetic process;2.33802834324656e-06!GO:0015078;hydrogen ion transmembrane transporter activity;2.44768089786988e-06!GO:0006357;regulation of transcription from RNA polymerase II promoter;2.4548087983343e-06!GO:0005768;endosome;2.50182625752576e-06!GO:0006754;ATP biosynthetic process;2.5864361182003e-06!GO:0006753;nucleoside phosphate metabolic process;2.5864361182003e-06!GO:0007059;chromosome segregation;3.16985006723138e-06!GO:0016481;negative regulation of transcription;3.29151390631035e-06!GO:0016310;phosphorylation;3.35346880652322e-06!GO:0005798;Golgi-associated vesicle;3.43308359234134e-06!GO:0016469;proton-transporting two-sector ATPase complex;3.52329703306605e-06!GO:0003899;DNA-directed RNA polymerase activity;3.80441558069472e-06!GO:0051246;regulation of protein metabolic process;4.14418128738328e-06!GO:0005788;endoplasmic reticulum lumen;4.18580527859299e-06!GO:0051427;hormone receptor binding;4.2016430129478e-06!GO:0004298;threonine endopeptidase activity;5.1925122797697e-06!GO:0007010;cytoskeleton organization and biogenesis;6.15700685955517e-06!GO:0048519;negative regulation of biological process;6.39115777711764e-06!GO:0006084;acetyl-CoA metabolic process;7.20264218609182e-06!GO:0006752;group transfer coenzyme metabolic process;8.1118950259405e-06!GO:0003724;RNA helicase activity;8.30486857491183e-06!GO:0016563;transcription activator activity;8.7425623979571e-06!GO:0006302;double-strand break repair;9.85172973987625e-06!GO:0009109;coenzyme catabolic process;1.0500391591033e-05!GO:0035257;nuclear hormone receptor binding;1.0500391591033e-05!GO:0006355;regulation of transcription, DNA-dependent;1.09077509990583e-05!GO:0006613;cotranslational protein targeting to membrane;1.25126379174304e-05!GO:0009117;nucleotide metabolic process;1.29698483762233e-05!GO:0030867;rough endoplasmic reticulum membrane;1.31697157623256e-05!GO:0009108;coenzyme biosynthetic process;1.32860346316068e-05!GO:0051052;regulation of DNA metabolic process;1.32860346316068e-05!GO:0051168;nuclear export;1.34693137354709e-05!GO:0051187;cofactor catabolic process;1.38230146309326e-05!GO:0016363;nuclear matrix;1.48180262414549e-05!GO:0000776;kinetochore;2.20344467667781e-05!GO:0003713;transcription coactivator activity;2.27446508327961e-05!GO:0005905;coated pit;2.50278447754684e-05!GO:0016564;transcription repressor activity;2.95441736679056e-05!GO:0006414;translational elongation;3.13009509064853e-05!GO:0005762;mitochondrial large ribosomal subunit;3.81035042347236e-05!GO:0000315;organellar large ribosomal subunit;3.81035042347236e-05!GO:0019899;enzyme binding;4.20589214502106e-05!GO:0015980;energy derivation by oxidation of organic compounds;4.58166078546793e-05!GO:0000139;Golgi membrane;4.60027091288915e-05!GO:0000082;G1/S transition of mitotic cell cycle;4.65624059999719e-05!GO:0043284;biopolymer biosynthetic process;4.86921747231878e-05!GO:0008654;phospholipid biosynthetic process;5.01423700051138e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;5.95491875370672e-05!GO:0007017;microtubule-based process;6.2067278038757e-05!GO:0007093;mitotic cell cycle checkpoint;6.91741076881631e-05!GO:0007088;regulation of mitosis;7.38280867258296e-05!GO:0006383;transcription from RNA polymerase III promoter;7.44981226820521e-05!GO:0015631;tubulin binding;9.04086056748506e-05!GO:0003714;transcription corepressor activity;9.45500517290821e-05!GO:0005525;GTP binding;0.000100326529885469!GO:0015077;monovalent inorganic cation transmembrane transporter activity;0.000100983072890227!GO:0044452;nucleolar part;0.000106377673047733!GO:0008033;tRNA processing;0.000129242395861014!GO:0065007;biological regulation;0.000135594484869921!GO:0003729;mRNA binding;0.000146261736708244!GO:0008022;protein C-terminus binding;0.000162030416477488!GO:0005791;rough endoplasmic reticulum;0.000170107446437829!GO:0000059;protein import into nucleus, docking;0.000174633884916287!GO:0016853;isomerase activity;0.000184117040388465!GO:0000786;nucleosome;0.000187908766046412!GO:0043021;ribonucleoprotein binding;0.000188367290742959!GO:0007052;mitotic spindle organization and biogenesis;0.000203755722272363!GO:0000228;nuclear chromosome;0.000207674434343014!GO:0006310;DNA recombination;0.000228706078146463!GO:0045454;cell redox homeostasis;0.000235535672796544!GO:0031968;organelle outer membrane;0.000235535672796544!GO:0016787;hydrolase activity;0.000255342732501783!GO:0044440;endosomal part;0.000258647727194555!GO:0010008;endosome membrane;0.000258647727194555!GO:0031988;membrane-bound vesicle;0.00026881342888863!GO:0003684;damaged DNA binding;0.000291255459632833!GO:0006612;protein targeting to membrane;0.000292579478063134!GO:0031252;leading edge;0.000342813596815498!GO:0003690;double-stranded DNA binding;0.000349993178128809!GO:0031072;heat shock protein binding;0.000350058815089573!GO:0005770;late endosome;0.000351060981791997!GO:0019867;outer membrane;0.000359394113524529!GO:0006275;regulation of DNA replication;0.000368702021316885!GO:0016023;cytoplasmic membrane-bound vesicle;0.000373613476300447!GO:0008186;RNA-dependent ATPase activity;0.000390235970852205!GO:0006338;chromatin remodeling;0.000417339367421852!GO:0005741;mitochondrial outer membrane;0.000418702968516754!GO:0000314;organellar small ribosomal subunit;0.000418702968516754!GO:0005763;mitochondrial small ribosomal subunit;0.000418702968516754!GO:0005769;early endosome;0.000428588293640633!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000430515679121159!GO:0006352;transcription initiation;0.000431732122716391!GO:0051789;response to protein stimulus;0.000442212560228687!GO:0006986;response to unfolded protein;0.000442212560228687!GO:0008092;cytoskeletal protein binding;0.000508851018850229!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.000508851018850229!GO:0006402;mRNA catabolic process;0.000509815937032797!GO:0006839;mitochondrial transport;0.000539011271749095!GO:0003678;DNA helicase activity;0.000549049251387083!GO:0005885;Arp2/3 protein complex;0.000581841361214507!GO:0005684;U2-dependent spliceosome;0.000581841361214507!GO:0016859;cis-trans isomerase activity;0.000613445999690938!GO:0004674;protein serine/threonine kinase activity;0.000624012319253433!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000640354661050225!GO:0005637;nuclear inner membrane;0.000648718982712159!GO:0032561;guanyl ribonucleotide binding;0.000671370816065047!GO:0019001;guanyl nucleotide binding;0.000671370816065047!GO:0030118;clathrin coat;0.000678369477562435!GO:0033116;ER-Golgi intermediate compartment membrane;0.000688877238825932!GO:0005876;spindle microtubule;0.000701767927460244!GO:0007050;cell cycle arrest;0.000750037152019522!GO:0008250;oligosaccharyl transferase complex;0.000770892637558853!GO:0000049;tRNA binding;0.00082488243990108!GO:0004527;exonuclease activity;0.000893152660802063!GO:0016126;sterol biosynthetic process;0.000911691374746162!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00097527705379498!GO:0042981;regulation of apoptosis;0.00101019765698621!GO:0019783;small conjugating protein-specific protease activity;0.00101205910358936!GO:0031982;vesicle;0.00102200707410696!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.00104540405412844!GO:0030658;transport vesicle membrane;0.00108727665904752!GO:0004004;ATP-dependent RNA helicase activity;0.00108727665904752!GO:0043067;regulation of programmed cell death;0.00108727665904752!GO:0004576;oligosaccharyl transferase activity;0.00111607617406215!GO:0003702;RNA polymerase II transcription factor activity;0.00115237775539864!GO:0046474;glycerophospholipid biosynthetic process;0.00116575879959215!GO:0030880;RNA polymerase complex;0.00117697281218017!GO:0004843;ubiquitin-specific protease activity;0.00119459879832908!GO:0005048;signal sequence binding;0.0012226785504591!GO:0000922;spindle pole;0.00125146064816188!GO:0016741;transferase activity, transferring one-carbon groups;0.00129597099428088!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.00129597099428088!GO:0032508;DNA duplex unwinding;0.00130343718972342!GO:0032392;DNA geometric change;0.00130343718972342!GO:0030133;transport vesicle;0.00135017695080428!GO:0031124;mRNA 3'-end processing;0.00136498212957221!GO:0003746;translation elongation factor activity;0.00137103084747887!GO:0046489;phosphoinositide biosynthetic process;0.00139652620066047!GO:0016790;thiolester hydrolase activity;0.00139907335112519!GO:0006611;protein export from nucleus;0.00140221121117793!GO:0030176;integral to endoplasmic reticulum membrane;0.00140905170503414!GO:0048471;perinuclear region of cytoplasm;0.00152271273303837!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00152387756241922!GO:0045892;negative regulation of transcription, DNA-dependent;0.0015404383108977!GO:0008168;methyltransferase activity;0.0015404383108977!GO:0048500;signal recognition particle;0.00154543375549562!GO:0031410;cytoplasmic vesicle;0.00162671830689016!GO:0051101;regulation of DNA binding;0.00166281761163086!GO:0008361;regulation of cell size;0.00167461036545921!GO:0043596;nuclear replication fork;0.00169661460804177!GO:0043069;negative regulation of programmed cell death;0.00179063947195562!GO:0000819;sister chromatid segregation;0.00180011651405536!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.00184213514626364!GO:0030660;Golgi-associated vesicle membrane;0.00189659504792877!GO:0016049;cell growth;0.00193081222759867!GO:0004221;ubiquitin thiolesterase activity;0.00196076495902073!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00209139738310876!GO:0006268;DNA unwinding during replication;0.00209723283960458!GO:0006270;DNA replication initiation;0.00211832803179054!GO:0006401;RNA catabolic process;0.0021234552313854!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00225721821724329!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00225721821724329!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00225721821724329!GO:0000070;mitotic sister chromatid segregation;0.0023722785010124!GO:0043681;protein import into mitochondrion;0.0025382836395799!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00254089013854522!GO:0043066;negative regulation of apoptosis;0.002606840087342!GO:0008312;7S RNA binding;0.00260890930737023!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00261122684252053!GO:0000428;DNA-directed RNA polymerase complex;0.00261122684252053!GO:0018196;peptidyl-asparagine modification;0.0026818656361645!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0026818656361645!GO:0035258;steroid hormone receptor binding;0.00279231378236524!GO:0006626;protein targeting to mitochondrion;0.0027942148487772!GO:0006695;cholesterol biosynthetic process;0.00279841613444736!GO:0007006;mitochondrial membrane organization and biogenesis;0.00279841613444736!GO:0006916;anti-apoptosis;0.00294801155364585!GO:0051252;regulation of RNA metabolic process;0.00299044664884508!GO:0000792;heterochromatin;0.00305052705993642!GO:0006892;post-Golgi vesicle-mediated transport;0.00311624785882811!GO:0030036;actin cytoskeleton organization and biogenesis;0.00314978069190404!GO:0030521;androgen receptor signaling pathway;0.00314978069190404!GO:0000910;cytokinesis;0.00317219794849817!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00320733421151677!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00320733421151677!GO:0006891;intra-Golgi vesicle-mediated transport;0.00321524429801163!GO:0009165;nucleotide biosynthetic process;0.00327282811183989!GO:0048487;beta-tubulin binding;0.00346477389857631!GO:0042393;histone binding;0.00346826960620863!GO:0006144;purine base metabolic process;0.00353873068064223!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00354968516510485!GO:0000287;magnesium ion binding;0.00356700565364763!GO:0030132;clathrin coat of coated pit;0.00368647670811344!GO:0006405;RNA export from nucleus;0.00387455994762171!GO:0001558;regulation of cell growth;0.00393313054707082!GO:0008017;microtubule binding;0.00402323996693129!GO:0051287;NAD binding;0.00440633783630289!GO:0043601;nuclear replisome;0.00440633783630289!GO:0030894;replisome;0.00440633783630289!GO:0008139;nuclear localization sequence binding;0.00442996664941745!GO:0016251;general RNA polymerase II transcription factor activity;0.00444275173172462!GO:0009112;nucleobase metabolic process;0.00446258837771168!GO:0030134;ER to Golgi transport vesicle;0.00455594319145808!GO:0051539;4 iron, 4 sulfur cluster binding;0.00487685377102623!GO:0031123;RNA 3'-end processing;0.00497826706469402!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.00497826706469402!GO:0046966;thyroid hormone receptor binding;0.00498029679482395!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00498029679482395!GO:0045047;protein targeting to ER;0.00498029679482395!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00498799050469039!GO:0030663;COPI coated vesicle membrane;0.00498799050469039!GO:0030126;COPI vesicle coat;0.00498799050469039!GO:0042802;identical protein binding;0.00531646998325519!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00541556188492312!GO:0046483;heterocycle metabolic process;0.00545487845988077!GO:0045936;negative regulation of phosphate metabolic process;0.00581253095798207!GO:0045893;positive regulation of transcription, DNA-dependent;0.0060738425555444!GO:0051098;regulation of binding;0.00621894087124485!GO:0000178;exosome (RNase complex);0.00634680196716566!GO:0006595;polyamine metabolic process;0.00663131894138992!GO:0051540;metal cluster binding;0.00667458349236198!GO:0051536;iron-sulfur cluster binding;0.00667458349236198!GO:0031570;DNA integrity checkpoint;0.00683715535961837!GO:0044454;nuclear chromosome part;0.00698229296550128!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;0.00726339676318834!GO:0045045;secretory pathway;0.00727446286914848!GO:0005669;transcription factor TFIID complex;0.00769809759202626!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.00785597845500854!GO:0046822;regulation of nucleocytoplasmic transport;0.00810247133428746!GO:0043130;ubiquitin binding;0.00814579698890095!GO:0032182;small conjugating protein binding;0.00814579698890095!GO:0006607;NLS-bearing substrate import into nucleus;0.00816143125281143!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.00825659556052083!GO:0015399;primary active transmembrane transporter activity;0.00825659556052083!GO:0006284;base-excision repair;0.00825873163767254!GO:0009303;rRNA transcription;0.008502898204543!GO:0030127;COPII vesicle coat;0.00851025734164933!GO:0012507;ER to Golgi transport vesicle membrane;0.00851025734164933!GO:0051087;chaperone binding;0.00855031717102063!GO:0003711;transcription elongation regulator activity;0.00862485205289291!GO:0005832;chaperonin-containing T-complex;0.00872695755724516!GO:0016197;endosome transport;0.0087428860041003!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00878142672988354!GO:0019206;nucleoside kinase activity;0.0091381786105751!GO:0006378;mRNA polyadenylation;0.00917794327486867!GO:0051920;peroxiredoxin activity;0.00925730338413397!GO:0007346;regulation of progression through mitotic cell cycle;0.00946973612845304!GO:0030518;steroid hormone receptor signaling pathway;0.00950461882127474!GO:0000725;recombinational repair;0.00951377061936693!GO:0000724;double-strand break repair via homologous recombination;0.00951377061936693!GO:0042770;DNA damage response, signal transduction;0.00996943007331736!GO:0046467;membrane lipid biosynthetic process;0.0100503370736013!GO:0005853;eukaryotic translation elongation factor 1 complex;0.0101244910680176!GO:0006818;hydrogen transport;0.0102945380442195!GO:0006506;GPI anchor biosynthetic process;0.0103887313132901!GO:0016272;prefoldin complex;0.0104147254302087!GO:0008286;insulin receptor signaling pathway;0.0104558373112492!GO:0030119;AP-type membrane coat adaptor complex;0.0105064002603708!GO:0016301;kinase activity;0.0105345206542075!GO:0006091;generation of precursor metabolites and energy;0.0107754688789784!GO:0015992;proton transport;0.0108147747122505!GO:0005862;muscle thin filament tropomyosin;0.0109603333680409!GO:0003923;GPI-anchor transamidase activity;0.0109626191788174!GO:0016255;attachment of GPI anchor to protein;0.0109626191788174!GO:0042765;GPI-anchor transamidase complex;0.0109626191788174!GO:0008276;protein methyltransferase activity;0.0109836455667574!GO:0030384;phosphoinositide metabolic process;0.0109836455667574!GO:0046112;nucleobase biosynthetic process;0.011293983665302!GO:0016044;membrane organization and biogenesis;0.0113760737553793!GO:0016584;nucleosome positioning;0.0114475653741591!GO:0006505;GPI anchor metabolic process;0.0117027410771823!GO:0030027;lamellipodium;0.0118019209971384!GO:0005773;vacuole;0.0118593638403358!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;0.0120211849229372!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.0120552671587781!GO:0006650;glycerophospholipid metabolic process;0.0120552671587781!GO:0019843;rRNA binding;0.0121237926102388!GO:0008097;5S rRNA binding;0.0121761598871788!GO:0044262;cellular carbohydrate metabolic process;0.0121778100903227!GO:0030137;COPI-coated vesicle;0.0124704647145037!GO:0043189;H4/H2A histone acetyltransferase complex;0.0127046877320364!GO:0009116;nucleoside metabolic process;0.012750486749243!GO:0016491;oxidoreductase activity;0.0128722558741934!GO:0006497;protein amino acid lipidation;0.0129241157530451!GO:0030029;actin filament-based process;0.0129655380290305!GO:0006367;transcription initiation from RNA polymerase II promoter;0.013074386199275!GO:0008287;protein serine/threonine phosphatase complex;0.0132094849817716!GO:0030131;clathrin adaptor complex;0.0132094849817716!GO:0030125;clathrin vesicle coat;0.013374512097658!GO:0030665;clathrin coated vesicle membrane;0.013374512097658!GO:0004003;ATP-dependent DNA helicase activity;0.0135398476691354!GO:0004518;nuclease activity;0.013811667608227!GO:0042326;negative regulation of phosphorylation;0.0138476178056601!GO:0016579;protein deubiquitination;0.01443826732216!GO:0000339;RNA cap binding;0.0144821080136284!GO:0035267;NuA4 histone acetyltransferase complex;0.014665117565878!GO:0006376;mRNA splice site selection;0.0147773377775973!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0147773377775973!GO:0008180;signalosome;0.0149714279884281!GO:0051053;negative regulation of DNA metabolic process;0.0150945062392948!GO:0005875;microtubule associated complex;0.0151283539887501!GO:0007264;small GTPase mediated signal transduction;0.0157707371651003!GO:0008408;3'-5' exonuclease activity;0.0157884951799888!GO:0016585;chromatin remodeling complex;0.0161523838685804!GO:0000123;histone acetyltransferase complex;0.0162016123869507!GO:0030496;midbody;0.0165815833827749!GO:0000152;nuclear ubiquitin ligase complex;0.0165815833827749!GO:0043022;ribosome binding;0.0170400970962397!GO:0004532;exoribonuclease activity;0.0171054988684292!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0171054988684292!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.0185058767592778!GO:0000086;G2/M transition of mitotic cell cycle;0.0189054610610939!GO:0000793;condensed chromosome;0.0193537494528862!GO:0045941;positive regulation of transcription;0.0199764614209726!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0201341691055603!GO:0005869;dynactin complex;0.0205151558005303!GO:0005663;DNA replication factor C complex;0.0207008001290762!GO:0031577;spindle checkpoint;0.0207563838593643!GO:0043488;regulation of mRNA stability;0.0207997074642031!GO:0043487;regulation of RNA stability;0.0207997074642031!GO:0008536;Ran GTPase binding;0.0209019373393885!GO:0032507;maintenance of cellular protein localization;0.0211326599000149!GO:0005652;nuclear lamina;0.0211832366946428!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0215542388749365!GO:0015002;heme-copper terminal oxidase activity;0.0215542388749365!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0215542388749365!GO:0004129;cytochrome-c oxidase activity;0.0215542388749365!GO:0008270;zinc ion binding;0.0222786627314892!GO:0008610;lipid biosynthetic process;0.0223452959966909!GO:0043624;cellular protein complex disassembly;0.0225338712901331!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0234121767688398!GO:0007021;tubulin folding;0.0234356709428479!GO:0051059;NF-kappaB binding;0.0234544584582235!GO:0017166;vinculin binding;0.0237745222307048!GO:0040029;regulation of gene expression, epigenetic;0.0240288632531731!GO:0000084;S phase of mitotic cell cycle;0.0240506629126848!GO:0065009;regulation of a molecular function;0.0246107250727544!GO:0050681;androgen receptor binding;0.0248735962959204!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0249378881962017!GO:0046426;negative regulation of JAK-STAT cascade;0.0249484870299213!GO:0008538;proteasome activator activity;0.0256318237058602!GO:0000077;DNA damage checkpoint;0.0261581503571042!GO:0000118;histone deacetylase complex;0.0265714226876211!GO:0003756;protein disulfide isomerase activity;0.0267039518255956!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0267039518255956!GO:0032984;macromolecular complex disassembly;0.0270310573010235!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0271856410949984!GO:0030140;trans-Golgi network transport vesicle;0.0273714476284073!GO:0051320;S phase;0.0280028625228336!GO:0050178;phenylpyruvate tautomerase activity;0.0286097625307571!GO:0031625;ubiquitin protein ligase binding;0.0286851474285816!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0287146742273518!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.0289202546413618!GO:0042791;5S class rRNA transcription;0.0293671161096896!GO:0000127;transcription factor TFIIIC complex;0.0293671161096896!GO:0042797;tRNA transcription from RNA polymerase III promoter;0.0293671161096896!GO:0003887;DNA-directed DNA polymerase activity;0.0294766931392146!GO:0006289;nucleotide-excision repair;0.0295194451687116!GO:0006672;ceramide metabolic process;0.0298419101353921!GO:0001832;blastocyst growth;0.0301644100250192!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.0303353293593091!GO:0046128;purine ribonucleoside metabolic process;0.0311900730721931!GO:0042278;purine nucleoside metabolic process;0.0311900730721931!GO:0043241;protein complex disassembly;0.0319155135885224!GO:0000209;protein polyubiquitination;0.0319155135885224!GO:0009113;purine base biosynthetic process;0.031936346692941!GO:0000726;non-recombinational repair;0.0323501781949238!GO:0043433;negative regulation of transcription factor activity;0.0324949751000473!GO:0009304;tRNA transcription;0.0326534045049741!GO:0005784;translocon complex;0.0337364756176763!GO:0006301;postreplication repair;0.0337364756176763!GO:0042158;lipoprotein biosynthetic process;0.0338238148955476!GO:0044438;microbody part;0.0338238148955476!GO:0044439;peroxisomal part;0.0338238148955476!GO:0008234;cysteine-type peptidase activity;0.0344807336244703!GO:0000323;lytic vacuole;0.0347923718445276!GO:0005764;lysosome;0.0347923718445276!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0347923718445276!GO:0010257;NADH dehydrogenase complex assembly;0.0347923718445276!GO:0033108;mitochondrial respiratory chain complex assembly;0.0347923718445276!GO:0005856;cytoskeleton;0.0349745741579842!GO:0030145;manganese ion binding;0.0350815896928773!GO:0008475;procollagen-lysine 5-dioxygenase activity;0.0357373279641504!GO:0043492;ATPase activity, coupled to movement of substances;0.0357373279641504!GO:0003857;3-hydroxyacyl-CoA dehydrogenase activity;0.0388508099741711!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.0393131587677241!GO:0008156;negative regulation of DNA replication;0.0396514984733224!GO:0030508;thiol-disulfide exchange intermediate activity;0.0398359092591832!GO:0016408;C-acyltransferase activity;0.0405458516337983!GO:0022411;cellular component disassembly;0.0407518307673279!GO:0043631;RNA polyadenylation;0.0411073486345849!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.0413425680289407!GO:0005938;cell cortex;0.0417879907150168!GO:0051651;maintenance of cellular localization;0.0417879907150168!GO:0045792;negative regulation of cell size;0.0419459562339257!GO:0030149;sphingolipid catabolic process;0.0419843447932641!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0423753479445844!GO:0031227;intrinsic to endoplasmic reticulum membrane;0.0426719877871099!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0432835180951405!GO:0004347;glucose-6-phosphate isomerase activity;0.0435703752017853!GO:0022890;inorganic cation transmembrane transporter activity;0.0437295523251831!GO:0019752;carboxylic acid metabolic process;0.0457514691022339!GO:0006740;NADPH regeneration;0.0458709897956408!GO:0006098;pentose-phosphate shunt;0.0458709897956408!GO:0003725;double-stranded RNA binding;0.0460912288610529!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0460912288610529!GO:0009451;RNA modification;0.0466456435736822!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.0467023929886431!GO:0005881;cytoplasmic microtubule;0.0470935908323723!GO:0051656;establishment of organelle localization;0.0472587066846579!GO:0031903;microbody membrane;0.0474100810014687!GO:0005778;peroxisomal membrane;0.0474100810014687!GO:0042026;protein refolding;0.0474100810014687!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0478473017220752!GO:0004185;serine carboxypeptidase activity;0.0488818512653832!GO:0030320;cellular monovalent inorganic anion homeostasis;0.0488818512653832!GO:0055083;monovalent inorganic anion homeostasis;0.0488818512653832!GO:0055064;chloride ion homeostasis;0.0488818512653832!GO:0030644;cellular chloride ion homeostasis;0.0488818512653832!GO:0005758;mitochondrial intermembrane space;0.048968356060306!GO:0031371;ubiquitin conjugating enzyme complex;0.0491108267445326!GO:0031301;integral to organelle membrane;0.0495962592094914!GO:0030308;negative regulation of cell growth;0.0497669432463015
|sample_id=12760
|sample_id=12760
|sample_note=
|sample_note=
Line 75: Line 104:
|sample_strain=
|sample_strain=
|sample_tissue=
|sample_tissue=
|time= 00hr00min
|timecourse=Saos_calcification
|top_motifs=PDX1:2.71420605908;TFDP1:2.09281133555;VSX1,2:1.83718861584;HOX{A4,D4}:1.63537506329;NFY{A,B,C}:1.59149270321;NKX2-3_NKX2-5:1.58792111239;E2F1..5:1.52684168045;NRF1:1.3753150316;NKX3-1:1.34059693162;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.32624644011;ZNF384:1.2095071455;PITX1..3:1.20271536682;ZNF143:1.17966996568;POU1F1:1.17778368796;PRRX1,2:1.09385797379;HIC1:1.08892499643;TOPORS:1.03092838818;EVI1:1.01097659789;EN1,2:1.00742457964;NFIX:0.972374942907;NKX6-1,2:0.968265473944;BREu{core}:0.938339873335;YY1:0.899682378467;GFI1:0.861869750318;CDC5L:0.788583213401;MEF2{A,B,C,D}:0.774645394712;RXR{A,B,G}:0.77330885815;PAX8:0.754509997334;SOX17:0.743772641805;NKX2-1,4:0.73549613734;FOXQ1:0.728222681513;IKZF2:0.727151044681;HIF1A:0.711209255189;PAX6:0.695058448762;PAX3,7:0.680968263199;FOXD3:0.67984146901;CUX2:0.672975236211;HES1:0.653863009287;MZF1:0.628806908873;T:0.576098790214;PAX1,9:0.566936470776;NR1H4:0.555955401983;PAX4:0.552787649793;PAX2:0.523328669091;MYB:0.517014026961;ZFP161:0.511782631308;FOXM1:0.502196647674;TFAP2B:0.477166298001;RREB1:0.455530948378;AIRE:0.452118800326;ZNF423:0.448463120228;FOXA2:0.435984968897;SOX{8,9,10}:0.408954208165;ATF4:0.405997098471;SP1:0.396419255216;PBX1:0.394849321674;LHX3,4:0.391959174708;XCPE1{core}:0.388009822123;ZBTB16:0.385702323615;STAT5{A,B}:0.3826276238;CDX1,2,4:0.373895080199;NFE2L2:0.373784615645;TEF:0.370197603629;TEAD1:0.366614791962;AHR_ARNT_ARNT2:0.362517816927;FOXP1:0.361302811122;NR3C1:0.348588782154;POU3F1..4:0.314760916496;UFEwm:0.303996537454;ELK1,4_GABP{A,B1}:0.30310082923;NR5A1,2:0.302962748798;TGIF1:0.277426404623;NANOG:0.276690802098;POU6F1:0.254360179761;PATZ1:0.251351329059;LEF1_TCF7_TCF7L1,2:0.243785999939;EGR1..3:0.198420927826;PRDM1:0.192616196806;NR6A1:0.190630432021;GTF2I:0.189542199632;ONECUT1,2:0.18663055944;ZIC1..3:0.186217168203;ESR1:0.167519114696;KLF4:0.162543737955;ATF6:0.156330187004;JUN:0.145483329583;FOX{F1,F2,J1}:0.127049447291;RUNX1..3:0.116632158526;SREBF1,2:0.114687441601;STAT1,3:0.100194229964;MYBL2:0.0955178803421;GATA4:0.0756370600894;ZBTB6:0.0649386532856;ATF5_CREB3:0.0391913874369;CREB1:0.0170768887022;NFE2L1:0.00881544892719;OCT4_SOX2{dimer}:-0.00222430644259;MED-1{core}:-0.0191878841013;TBX4,5:-0.0263206906881;MTE{core}:-0.0322340085668;HOX{A5,B5}:-0.035462173424;GTF2A1,2:-0.048043655742;IKZF1:-0.0597883433338;ARID5B:-0.0616627365095;DBP:-0.0658243752017;FOXP3:-0.0690026415995;FOXN1:-0.0824887675871;RBPJ:-0.0899549926312;HNF1A:-0.100009552996;MYFfamily:-0.106097904704;XBP1:-0.111152623675;RFX1:-0.117728018216;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.131146841899;ESRRA:-0.134057550846;GFI1B:-0.142566574794;NFE2:-0.149557398446;MAZ:-0.149602927613;TFAP4:-0.156859125014;ALX4:-0.170449065604;GZF1:-0.174503961031;EBF1:-0.174904538908;HNF4A_NR2F1,2:-0.186254107878;FOXL1:-0.188243834325;BACH2:-0.20937490508;REST:-0.231874870267;CRX:-0.232483979801;bHLH_family:-0.243604141438;GLI1..3:-0.25001179718;RFX2..5_RFXANK_RFXAP:-0.251212190166;POU5F1:-0.252662923945;AR:-0.253557370791;FOSL2:-0.25914869082;IRF7:-0.26501547727;FOX{I1,J2}:-0.269469045817;RORA:-0.27364469387;GCM1,2:-0.286776307585;FOS_FOS{B,L1}_JUN{B,D}:-0.29695576459;DMAP1_NCOR{1,2}_SMARC:-0.297622434664;SOX5:-0.317105082548;NKX3-2:-0.317966003168;GATA6:-0.324678985752;ZNF238:-0.335830355222;TFCP2:-0.338932359204;ADNP_IRX_SIX_ZHX:-0.358987514919;HLF:-0.372716919453;TLX1..3_NFIC{dimer}:-0.374701937201;TFAP2{A,C}:-0.378815608946;HOXA9_MEIS1:-0.390481382785;SOX2:-0.416625805828;NHLH1,2:-0.438955543125;ELF1,2,4:-0.445177084925;SMAD1..7,9:-0.4597195042;RXRA_VDR{dimer}:-0.468785979958;NFIL3:-0.476457314082;TP53:-0.489444098372;NFKB1_REL_RELA:-0.49608558489;PAX5:-0.502853326236;SRF:-0.503967982841;MTF1:-0.520002021062;MYOD1:-0.527148276108;ZNF148:-0.528019029815;TAL1_TCF{3,4,12}:-0.52862483224;IRF1,2:-0.535958409356;SNAI1..3:-0.543362110545;SPIB:-0.549783666409;MAFB:-0.557412843889;SPI1:-0.570350067031;BPTF:-0.587047182847;SPZ1:-0.61447061436;LMO2:-0.653079078502;ZEB1:-0.653748487161;HAND1,2:-0.668497142314;POU2F1..3:-0.670762286279;ATF2:-0.705760257722;NKX2-2,8:-0.741962221432;ALX1:-0.751608902648;HMGA1,2:-0.770391221143;ETS1,2:-0.779958781901;NANOG{mouse}:-0.817700339313;PPARG:-0.819028518297;HMX1:-0.85176513836;FOX{D1,D2}:-0.86349801592;CEBPA,B_DDIT3:-0.876610061171;HOX{A6,A7,B6,B7}:-0.91385263909;STAT2,4,6:-0.955940557821;HBP1_HMGB_SSRP1_UBTF:-1.05558553167;FOXO1,3,4:-1.22625889201;HSF1,2:-1.2319651436;TBP:-1.25287166499;NFATC1..3:-1.26722244612;EP300:-1.33588564296;TLX2:-1.37007261095
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|xref=
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:12760-136B6;search_select_hide=table117:FF:12760-136B6
}}
}}

Latest revision as of 18:44, 4 June 2020

Name:Saos-2 osteosarcoma treated with ascorbic acid and BGP to induce calcification
Species:Human (Homo sapiens)
Library ID:CNhs12859
Sample type:time courses
Genomic View: UCSC
RefEX:Specific genes
CAGEd-oPOSSUM:link
ZENBU report :link
Additional information
Sample information
strainNA
tissueNA
dev stageNA
sexfemale
ageNA
cell typeosteoblast
cell lineSaos-2
companyNA
collaborationKim Summers (Roslin Institute)
External link for information[{{{sample_info_link}}} {{{sample_info_link}}}]
RNA information
lot numberNA
catalog numberNA
sample typeNA
extraction protocol (Details)OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0

CAGE Accession numbers
MethodSample accession id
CAGE  SAMD00004881
Library accession numbers

Library idMethodExp. accession idRun accession id
CNhs12859 CAGE DRX008601 DRR009473
Accession ID Hg19

Library idBAMCTSS
CNhs12859 DRZ000898 DRZ002283
Accession ID Hg38

Library idBAMCTSS
CNhs12859 DRZ012248 DRZ013633
Download raw sequence, BAM & CTSS
Hg19
FastaBAMCTSS
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Hg38
BAMCTSS
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RNA-Seq Accession numbers
MethodSample accession id
sRNA-Seq  SAMD00004881
Library accession numbers

Library idMethodExp. accession idRun accession id
SRhi10065.GTGGCC sRNA-Seq DRX037313 DRR041679
Accession ID Hg19

Library idBAMCTSS
SRhi10065.GTGGCC DRZ007321


Relative expression to median (log10)


Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.



Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data

Coexpression clusterscore
C0-CD14-Eosinophils-Neutrophils-Basophils-CD34-immature-Peripheral0
C1-testis-epididymis-embryonic-medulla-pituitary-trachea-caudate0
C10-occipital-temporal-parietal-brain-duodenum-Neurons-Neural0
C100-rhabdomyosarcoma-gastric-pineal-Wilms-cervical-mesodermal-endometrial0
C101-small-cerebellum-maxillary-colon-parietal-epididymis-merkel0
C102-neuroblastoma-testicular-pituitary-carcinosarcoma-rectum-acantholytic-iPS0
C103-CD4-CD8-Natural-Peripheral-Whole-Neutrophils-Basophils0
C104-Mast-Basophils-immature-CD14-CD34-eye-Natural0
C105-heart-skeletal-occipital-hippocampus-acute-Sebocyte-penis0.147
C106-Hep2-epitheloid-placenta-cervical-rectal-anaplastic-glassy0
C107-Neutrophils-CD14-Eosinophils-Monocytederived-Whole-Peripheral-blood0
C108-breast-hepatoblastoma-MCF7-parotid-salivary-submaxillary-prostate0
C109-Reticulocytes-non-acute-Hodgkin-Burkitt-retinoblastoma-lymphoma0.586
C11-cerebellum-medulla-pons-parietal-occipital-middle-medial0
C110-leukemia-chronic-Eosinophils-acute-Whole-CD34-Lymphatic0
C111-medulla-lung-trachea-testis-caudate-epididymis-throat0
C112-gastric-pancreas-temporal-duodenum-small-extraskeletal-adrenal0
C113-thyroid-throat-lung-lymph-small-colon-trachea0
C114-teratocarcinoma-medulloblastoma-carcinosarcoma-iPS-anaplastic-acute-neuroblastoma0
C115-pituitary-Neural-caudate-putamen-amygdala-medulla-hippocampus0
C116-myeloma-xeroderma-tonsil-CD19-spleen-lymph-trachea0
C117-serous-clear-kidney-neuroectodermal-mesothelioma-endometrial-Intestinal0
C118-cerebellum-parietal-occipital-medial-middle-frontal-insula0
C119-CD4-CD8-Natural-Neutrophils-CD14-Peripheral-CD190.0381
C12-Mast-Basophils-immature-chorionic-mature-CD14-Eosinophils0
C120-immature-salivary-tongue-skin-cervical-CD14-CD340
C121-NK-Natural-CD8-CD4-anaplastic-chronic-B0
C122-chronic-Reticulocytes-skeletal-leukemia-acute-colon-Tracheal0
C123-CD19-Natural-CD8-CD4-CD14-Peripheral-Basophils0
C124-small-temporal-duodenum-colon-gall-signet-Hepatocyte0
C125-mucinous-alveolar-mesothelioma-Smooth-lung-CD14-Nucleus0
C126-gastrointestinal-argyrophil-smallcell-merkel-bile-insula-brain0
C127-maxillary-small-hepatoblastoma-hepatocellular-alveolar-colon-argyrophil0
C128-testicular-choriocarcinoma-H9-teratocarcinoma-pancreatic-iPS-HES3GFP0
C129-liver-Hepatocyte-colon-duodenum-temporal-testicular-small0
C13-Neutrophils-Eosinophils-CD14-Monocytederived-Whole-Peripheral-CD40
C130-iPS-HES3GFP-H9-teratocarcinoma-testicular-colon-Alveolar0
C131-lung-trachea-Alveolar-thyroid-umbilical-throat-skin0
C132-acute-small-Dendritic-Macrophage-CD14-Neutrophils-Monocytederived0
C133-signet-gall-small-kidney-colon-ductal-adenocarcinoma0
C134-skeletal-diaphragm-tongue-throat-Skeletal-skin-penis0
C135-neuroblastoma-retinoblastoma-carcinoid-choriocarcinoma-testicular-acute-rectum0
C136-Wilms-extraskeletal-anaplastic-rhabdomyosarcoma-cholangiocellular-nonsmall-neuroectodermal0
C137-large-ductal-melanoma-cervical-Endothelial-Smooth-chronic0
C138-diffuse-Burkitt-lymphangiectasia-lymphoma-acute-CD19-pineal0
C139-astrocytoma-skin-salivary-gall-serous-Mallassezderived-renal0
C14-Whole-blood-Reticulocytes-liver-Neutrophils-Eosinophils-spleen0
C140-Renal-Endothelial-Hepatic-Lymphatic-heart-lung-spleen0
C141-Hodgkin-acute-thymus-chronic-vein-CD4-B0
C142-Preadipocyte-Fibroblast-hepatic-Ewing-Adipocyte-Olfactory-Hair0
C143-Monocytederived-CD14-Macrophage-Dendritic-Basophils-CD14CD16-Osteoblast0
C144-CD4-tonsil-NK-appendix-CD8-splenic-mycosis0
C145-neuroblastoma-peripheral-neuroectodermal-neuroepithelioma-carcinoid-adult-extraskeletal0
C146-lymphangiectasia-lymphoma-gall-lymph-tonsil-gastric-transitionalcell0
C147-Neutrophils-Eosinophils-CD4-CD14-CD8-Natural-Peripheral0
C148-kidney-small-epididymis-pancreas-serous-duodenum-temporal0
C149-occipital-medial-brain-amygdala-parietal-cerebral-cerebellum0
C15-anaplastic-small-skeletal-neuroblastoma-parietal-temporal-tongue0
C150-merkel-carcinoid-nonsmall-gastrointestinal-argyrophil-pineal-small0
C151-CD14-Natural-Basophils-CD8-Eosinophils-CD4-Mast0
C152-peripheral-neuroectodermal-neuroepithelioma-neuroblastoma-testicular-carcinoid-lung0
C153-rhabdomyosarcoma-liposarcoma-pancreatic-somatostatinoma-Reticulocytes-lymphoma-testicular0
C154-adenocarcinoma-Mesenchymal-Cardiac-small-sacrococcigeal-Smooth-Prostate0
C155-pituitary-placenta-nonsmall-cervical-smallcell-choriocarcinoma-epitheloid0
C156-plasma-splenic-hereditary-B-large-xeroderma-b0
C157-testicular-H9-testis-iPS-teratocarcinoma-colon-trachea0
C158-adrenal-gastric-temporal-parietal-duodenum-caudate-putamen0
C159-choriocarcinoma-pancreatic-placenta-chorionic-testicular-bronchioalveolar-seminal0
C16-medial-amygdala-occipital-parietal-olfactory-putamen-brain0
C160-medulla-Hepatocyte-retina-corpus-liver-pineal-cerebral0
C161-mesothelioma-Mesothelial-acute-mesenchymal-extraskeletal-renal-placenta0
C162-spinal-locus-medulla-substantia-thalamus-globus-diencephalon0
C163-Skeletal-skeletal-Pericytes-Hepatic-rhabdomyosarcoma-throat-mesenchymal0
C164-signet-corpus-optic-mucinous-substantia-salivary-choriocarcinoma0
C165-epithelioid-Adipocyte-mesothelioma-myxofibrosarcoma-lung-gastric-Mesothelial0
C166-Macrophage-Monocytederived-Dendritic-adipose-lymph-CD14-lung0
C167-Basophils-Mast-Eosinophils-Neutrophils-Peripheral-Whole-CD40
C168-Mast-CD14-immature-Basophils-Eosinophils-CD34-Peripheral0
C169-hereditary-adult-gall-lymphangiectasia-chronic-b-choriocarcinoma0
C17-Mast-CD14-Monocytederived-Lymphatic-Smooth-mesenchymal-Macrophage0
C170-epitheloid-cervical-Hep2-keratoacanthoma-adult-neuroblastoma-signet0
C171-merkel-neuroblastoma-pineal-retinoblastoma-carcinoid-small-eye0
C172-chorionic-skeletal-tongue-amniotic-liver-gastrointestinal-Pericytes0
C173-Adipocyte-mature-skin-left-Hepatocyte-Osteoblast-adipose0
C174-CD14-Neutrophils-Smooth-mesothelioma-embryonic-Monocytederived-Eosinophils0
C175-Eosinophils-Neutrophils-CD4-Basophils-CD19-CD8-Natural0
C176-Eosinophils-Neutrophils-Mast-CD14-CD4-Basophils-CD19-0.0103
C177-melanoma-Melanocyte-mesenchymal-retina-Mallassezderived-Gingival-squamous0
C178-spleen-liver-Hepatocyte-b-lymph-vein-thymus0
C179-CD19-Peripheral-lymphoma-blood-lymph-spleen-tonsil0
C18-CD4-CD8-thymus-Whole-Peripheral-Natural-blood0
C180-skeletal-heart-Hepatocyte-acute-occipital-hippocampus-middle0.0164
C181-liposarcoma-somatostatinoma-neuroblastoma-mesothelioma-nonsmall-small-Alveolar0
C182-renal-mature-mesothelioma-lung-Mammary-Adipocyte-acute0
C183-acute-non-CD34-diffuse-CD133-myeloma-Burkitt0
C184-somatostatinoma-smallcell-nonsmall-small-gastrointestinal-pineal-thyroid0
C185-small-adrenal-gastric-Mesenchymal-acute-HES3GFP-testis0
C186-squamous-papillotubular-large-Tracheal-oral-Small-epidermoid0
C187-migratory-immature-Dendritic-CD19-CD14-Monocytederived-Macrophage0
C188-left-heart-tongue-skeletal-Skeletal-diaphragm-throat0
C189-b-splenic-tonsil-CD19-lymph-appendix-spleen0
C19-embryonic-testis-cord-chronic-CD14-NK-mesothelioma0
C190-colon-small-rectum-duodenum-appendix-temporal-oral0
C191-leiomyoblastoma-Mast-parietal-acute-bone-neuroepithelioma-embryonic0
C192-Neutrophils-CD14-Peripheral-Eosinophils-CD8-Natural-CD40
C193-Mesenchymal-Adipocyte-mature-Cardiac-heart-CD14CD16-CD140
C194-MCF7-breast-prostate-Intestinal-diffuse-Wilms-Alveolar0
C195-Small-Gingival-Bronchial-Smooth-mesenchymal-Urothelial-Tracheal0
C196-testicular-iPS-H9-teratocarcinoma-HES3GFP-choriocarcinoma-endometrial0
C197-tongue-esophagus-tonsil-salivary-cervix-nasal-Gingival0
C198-Mesenchymal-Hair-Hepatic-Fibroblast-Smooth-tenocyte-Pericytes0.0843
C199-glioblastoma-B-osteosarcoma-Fibroblast-heart-rhabdomyosarcoma-myxofibrosarcoma0
C2-Eosinophils-Neutrophils-CD14-Whole-Basophils-Peripheral-Mast0
C20-heart-left-skeletal-diaphragm-tongue-umbilical-throat0
C200-seminal-Cardiac-Smooth-Hair-submaxillary-Neutrophils-mixed-0.0982
C201-colon-small-adenocarcinoma-duodenum-temporal-signet-gall0
C202-salivary-skin-penis-tongue-uterus-cervical-immature0
C203-acute-NK-chronic-CD133-lymphoma-immature-Dendritic0
C204-Smooth-nasal-CD4-CD19-CD8-CD14-CD340
C205-mycosis-cord-hairy-xeroderma-CD4-B-b0
C206-melanoma-somatostatinoma-nonsmall-small-neuroblastoma-smallcell-pituitary0
C207-Corneal-Keratinocyte-Esophageal-Mammary-Bronchial-Urothelial-Sebocyte0
C208-skin-amniotic-papillotubular-salivary-umbilical-Alveolar-serous0
C209-acute-myelodysplastic-CD34-granulocyte-CD133-liver-spleen0
C21-cord-mycosis-hairy-xeroderma-adult-CD4-anaplastic0
C210-Burkitt-lymphoma-appendix-acute-diffuse-CD19-tonsil0
C211-small-Hepatocyte-liver-colon-temporal-duodenum-kidney0
C212-chronic-acute-Whole-Reticulocytes-leukemia-blood-CD340
C213-CD14-Natural-CD8-CD4-Basophils-Eosinophils-Peripheral0
C214-Neurons-Neural-duodenum-temporal-occipital-parietal-brain0
C215-chronic-acute-peripheral-Hepatocyte-osteosarcoma-NK-immature0
C216-osteosarcoma-Smooth-Mesenchymal-large-neuroectodermal-acute-CD340.073
C217-carcinoid-neuroectodermal-mature-mesodermal-colon-acute-occipital0
C218-tonsil-lymph-CD19-spleen-colon-appendix-salivary0
C219-nasal-Basophils-amniotic-Melanocyte-CD14-Osteoblast-duodenum0
C22-CD4-CD8-Natural-Basophils-CD14-Peripheral-CD190
C220-Adipocyte-mature-left-breast-skin-liver-adipose0
C221-alveolar-Osteoblast-Myoblast-mesenchymal-liposarcoma-Smooth-hepatocellular0
C222-Melanocyte-Tracheal-Neutrophils-seminal-Smooth-Hair-Chondrocyte-0.144
C223-Chondrocyte-basal-renal-Fibroblast-Smooth-spindle-Synoviocyte0
C224-clear-serous-pleomorphic-choriocarcinoma-mesothelioma-amniotic-renal0
C225-ductal-alveolar-giant-prostate-salivary-squamous-Tracheal0
C226-Corneal-Keratinocyte-Esophageal-Urothelial-Mammary-Bronchial-Tracheal0
C227-chorionic-amniotic-Mesenchymal-Placental-gastric-diaphragm-tongue0
C228-colon-Intestinal-Prostate-hepatoblastoma-hepatocellular-testis-adult0
C229-Mesenchymal-CD4-Melanocyte-acute-skeletal-left-heart0
C23-CD4-CD8-Natural-Peripheral-Basophils-CD19-CD140
C230-aorta-normal-heart-penis-osteosarcoma-basal-lung0
C231-Mesothelial-mesenchymal-mesothelioma-Fibroblast-Preadipocyte-leiomyoma-mycosis0
C232-teratocarcinoma-HES3GFP-H9-iPS-testicular-neuroblastoma-cerebellum0
C233-uterus-cervix-ovary-epididymis-colon-rectum-MCF70
C234-oral-epidermoid-malignant-cervical-ductal-lung-keratoacanthoma0
C235-Intestinal-Prostate-liver-colon-small-kidney-pancreas0
C236-CD14-Neutrophils-Monocytederived-renal-Eosinophils-testis-mesothelioma0
C237-acute-breast-testicular-hepatoblastoma-chronic-argyrophil-Bronchial0
C238-stomach-gall-breast-duodenum-temporal-MCF7-smallcell0
C239-CD4-lymphangiectasia-CD8-NK-mycosis-Renal-hairy0
C24-pineal-eye-retina-retinoblastoma-medulloblastoma-small-cerebral0
C240-Adipocyte-Preadipocyte-Osteoblast-Chondrocyte-tenocyte-Synoviocyte-mesenchymal0
C241-Reticulocytes-chronic-Tracheal-Hodgkin-Endothelial-Hair-thymus0.438
C242-acute-Chondrocyte-myelodysplastic-granulocyte-biphenotypic-Fibroblast-stomach0
C243-Chondrocyte-trachea-Synoviocyte-mesodermal-renal-Fibroblast-Ewing0
C244-CD14-Monocytederived-Hepatocyte-heart-Neutrophils-acute-Macrophage0
C245-prostate-penis-salivary-esophagus-kidney-Neutrophils-Pancreatic0
C246-Neutrophils-Eosinophils-Whole-CD14-CD14CD16-Basophils-migratory0
C247-pons-locus-medulla-spinal-paracentral-medial-occipital0
C248-iPS-Aortic-Hep2-amygdala-acute-medial-Myoblast0
C249-nonsmall-small-smallcell-occipital-somatostatinoma-maxillary-medial0
C25-small-colon-temporal-duodenum-liver-Hepatocyte-gall0
C250-Mast-Neutrophils-CD14-Eosinophils-CD8-Peripheral-CD40
C251-gall-tonsil-trachea-CD14-salivary-throat-tongue0
C252-hepatic-Olfactory-sacrococcigeal-leiomyoma-normal-Synoviocyte-glioblastoma0
C253-spleen-rhabdomyosarcoma-Hepatocyte-small-uterus-liver-rectum0
C254-prostate-rhabdomyosarcoma-seminal-Fibroblast-transitionalcell-Smooth-Iris0
C255-Wilms-leiomyoblastoma-kidney-adrenal-MCF7-epithelioid-Mast0
C256-occipital-caudate-amygdala-medial-thalamus-hippocampus-medulla0
C257-pineal-insula-frontal-occipital-temporal-medial-paracentral0
C258-hepatoblastoma-hepatocellular-signet-colon-Intestinal-Prostate-gastric0
C259-Preadipocyte-Adipocyte-Fibroblast-Chondrocyte-tenocyte-normal-Ewing0.105
C26-Eosinophils-Neutrophils-CD14-CD14CD16-Basophils-Monocytederived-Whole0
C260-acute-chronic-Natural-NK-Basophils-biphenotypic-blood0
C261-locus-medial-parietal-pons-diencephalon-olfactory-spinal0
C262-breast-MCF7-skeletal-Reticulocytes-mucinous-hepatoblastoma-Wilms0
C263-cervical-keratoacanthoma-tongue-skin-esophagus-throat-tonsil0
C264-giant-keratoacanthoma-colon-fibrosarcoma-HES3GFP-Hep2-acute0
C265-CD4-Eosinophils-CD14-Natural-CD19-Basophils-CD80
C266-acute-chronic-leukemia-small-choriocarcinoma-hepatoma-Mast0
C267-pancreatic-placenta-choriocarcinoma-testicular-teratocarcinoma-chorionic-clear0
C268-Mallassezderived-Urothelial-Gingival-Small-Bronchial-Tracheal-Prostate0
C269-Basophils-Mast-Eosinophils-mature-CD14-chorionic-CD40
C27-pancreas-temporal-duodenum-salivary-ductus-umbilical-lung0
C270-CD4-Fibroblast-acute-iPS-Aortic-CD34-Smooth0
C271-pineal-spinal-locus-globus-medulla-thalamus-cerebellum0
C272-CD19-CD4-CD8-Whole-Peripheral-lymph-tonsil0
C273-Neutrophils-CD14-Eosinophils-Monocytederived-CD4-Natural-Mast0.0381
C274-CD14-Mast-immature-Basophils-mature-vagina-Hepatocyte0
C275-pons-medulla-cerebellum-locus-thalamus-diencephalon-spinal0
C276-mesothelioma-kidney-renal-small-clear-cerebellum-Renal0
C277-mesothelioma-epithelioid-thyroid-extraskeletal-alveolar-glioblastoma-adenocarcinoma0
C278-amygdala-hippocampus-insula-medial-putamen-temporal-olfactory0
C279-parietal-cerebellum-occipital-temporal-middle-duodenum-medial0
C28-thymus-acute-vein-Hodgkin-chronic-throat-Dendritic0
C280-Mast-Natural-CD19-CD8-Eosinophils-CD34-CD40
C281-Hodgkin-Reticulocytes-chronic-NK-acute-retinoblastoma-small0.583
C282-acute-B-tonsil-CD19-submaxillary-lymph-throat0
C283-tenocyte-Chondrocyte-mesenchymal-Macrophage-pleomorphic-Synoviocyte-cholangiocellular0
C284-parietal-occipital-medial-temporal-olfactory-locus-hippocampus0
C285-cervical-Hep2-small-colon-temporal-duodenum-bronchogenic0
C286-cerebellum-occipital-optic-parietal-globus-caudate-medial0.105
C287-Hepatocyte-Chondrocyte-Adipocyte-Synoviocyte-liver-tenocyte-mesenchymal0
C288-Chondrocyte-Renal-Pericytes-Fibroblast-aorta-Smooth-Meningeal0
C289-chorionic-skeletal-heart-Mast-amniotic-granulosa-left0
C29-mature-adipose-Adipocyte-breast-Lymphatic-vein-heart0
C290-Eosinophils-CD14-Basophils-Mast-CD4-CD8-immature0
C291-spinal-substantia-retina-medulla-tongue-skeletal-trachea0
C292-Mesenchymal-skin-umbilical-Adipocyte-mesenchymal-Chondrocyte-skeletal0
C293-CD14-CD14CD16-Basophils-Peripheral-immature-Eosinophils-CD340
C294-CD14-Macrophage-Monocytederived-CD14CD16-Neutrophils-Basophils-Peripheral0
C295-Fibroblast-Smooth-Myoblast-Chondrocyte-hepatic-Synoviocyte-Preadipocyte0
C296-gall-small-mesothelioma-acute-bronchioalveolar-epidermoid-mixed0
C297-Eosinophils-CD4-Basophils-Natural-Neutrophils-CD8-Peripheral0
C298-small-optic-substantia-thalamus-diencephalon-globus-occipital0
C299-CD14CD16-Eosinophils-Neutrophils-CD14-Whole-Basophils-blood0
C3-occipital-temporal-insula-medial-postcentral-frontal-amygdala0
C30-thyroid-throat-mesothelioma-mucinous-trachea-chorionic-mesenchymal0
C300-CD4-CD8-NK-Natural-blood-mycosis-Basophils0
C301-Smooth-mesenchymal-Endothelial-Hepatic-basal-hepatic-chorionic0
C302-acute-peripheral-Neutrophils-NK-myelodysplastic-CD34-carcinoid0
C303-CD14-Basophils-Peripheral-Eosinophils-CD14CD16-Neutrophils-Whole0
C305-heart-skeletal-smooth-left-bladder-penis-esophagus0
C31-skeletal-tongue-diaphragm-throat-penis-skin-trachea0
C32-middle-occipital-parietal-hippocampus-amygdala-medial-olfactory0
C33-Reticulocytes-liver-Whole-blood-chronic-acute-spleen0
C34-placenta-chorionic-choriocarcinoma-mesothelioma-Wilms-Smooth-bile0
C35-caudate-putamen-diencephalon-nucleus-globus-thalamus-insula0
C36-B-b-splenic-plasma-xeroderma-adrenal-Burkitt0
C37-salivary-submaxillary-parotid-seminal-tongue-ductus-trachea0
C38-extraskeletal-rhabdomyosarcoma-adrenal-rectal-mesothelioma-lung-Wilms0
C39-epididymis-ductus-seminal-testis-acute-thyroid-CD1330
C4-optic-corpus-substantia-medulla-spinal-thalamus-globus0
C40-eye-retina-Lens-pineal-tongue-retinoblastoma-small0
C41-retina-eye-medulla-Retinal-medulloblastoma-kidney-pineal0
C42-small-lung-maxillary-pharyngeal-Mesenchymal-Wilms-colon0
C43-ductus-seminal-duodenum-temporal-gall-prostate-bladder0
C44-Dendritic-CD19-CD133-granulocyte-acute-thymus-immature0
C45-testicular-choriocarcinoma-H9-teratocarcinoma-Wilms-pancreatic-iPS0
C46-acute-Hodgkin-thymus-CD8-chronic-CD4-merkel0
C47-CD19-Burkitt-acute-xeroderma-tonsil-lymphoma-appendix0
C48-smooth-bladder-esophagus-colon-penis-aorta-uterus0
C49-H9-iPS-testicular-HES3GFP-teratocarcinoma-hepatoblastoma-choriocarcinoma0
C5-Hepatocyte-liver-hepatocellular-Intestinal-kidney-small-pancreas0
C50-chorionic-placenta-amniotic-migratory-smallcell-chronic-choriocarcinoma0
C51-kidney-mesothelioma-renal-signet-gall-lung-pancreas0
C52-adult-NK-chronic-cord-testis-embryonic-myeloma0
C53-medulloblastoma-pineal-retinoblastoma-small-retina-eye-pituitary0
C54-Dendritic-Macrophage-Monocytederived-CD14-leiomyoma-adipose-immature0
C55-hepatocellular-Intestinal-liver-Prostate-fibrosarcoma-Hepatocyte-hepatoblastoma0
C56-heart-left-umbilical-skeletal-penis-diaphragm-tongue0
C57-Neutrophils-Eosinophils-Whole-CD4-CD8-CD19-Natural0
C58-Melanocyte-melanoma-retina-Retinal-eye-migratory-H90
C59-Smooth-Fibroblast-Mesenchymal-tenocyte-Ewing-skin-hepatic0.073
C6-CD14-Eosinophils-Basophils-Peripheral-CD34-Natural-immature0
C60-esophagus-tonsil-throat-tongue-uterus-cervix-cervical0
C61-migratory-Dendritic-immature-Macrophage-xeroderma-cord-b0
C62-Burkitt-tonsil-CD19-submaxillary-spleen-salivary-lymph0
C63-neuroectodermal-neuroblastoma-carcinoid-peripheral-chronic-neuroepithelioma-acute0
C64-Mast-chronic-acute-immature-chorionic-Basophils-Dendritic0
C65-CD14-Eosinophils-Monocytederived-Basophils-immature-Macrophage-Neutrophils0
C66-cerebellum-middle-occipital-parietal-medial-amygdala-hippocampus0
C67-CD14-Monocytederived-Macrophage-dura-Dendritic-spleen-lung0
C68-amniotic-chorionic-Placental-salivary-placenta-tongue-mesothelioma0
C69-anaplastic-CD14-cord-hairy-mycosis-adult-NK0
C7-CD14-Eosinophils-Neutrophils-Smooth-Basophils-Macrophage-Mast0
C70-parotid-submaxillary-salivary-throat-trachea-aorta-tongue0
C71-Monocytederived-Macrophage-CD14-Dendritic-Osteoblast-leiomyoma-Prostate0
C72-skeletal-tongue-throat-heart-diaphragm-penis-left0
C73-pineal-eye-retina-caudate-cerebellum-left-parietal0
C74-splenic-B-b-plasma-xeroderma-lymphoma-hairy0
C75-Eosinophils-Natural-CD8-Basophils-CD14-CD4-Peripheral0
C76-argyrophil-gastrointestinal-temporal-duodenum-neuroblastoma-merkel-smallcell0
C77-Saos2-osteosarcoma-Neutrophils-Natural-Chondrocyte-Basophils-CD80.604
C78-lymphoma-plasma-tonsil-appendix-lymph-seminal-trachea0
C79-chorionic-Chondrocyte-Cardiac-Smooth-Fibroblast-Preadipocyte-Mesenchymal0
C8-Natural-CD8-Basophils-CD4-CD14-Peripheral-CD340
C80-immature-migratory-CD14-Dendritic-splenic-cord-Mast0
C81-trachea-salivary-throat-aorta-eye-submaxillary-parotid0
C82-Basophils-CD14-Eosinophils-Natural-Peripheral-immature-CD340
C83-choriocarcinoma-pancreatic-placenta-chorionic-HES3GFP-testicular-amniotic0
C84-choriocarcinoma-pancreatic-Wilms-Mallassezderived-thymus-salivary-colon0
C85-neuroblastoma-carcinoid-retinoblastoma-small-pineal-rhabdomyosarcoma-medulloblastoma0
C86-colon-carcinoid-small-neuroectodermal-giant-large-neuroepithelioma0
C87-retinoblastoma-left-nonsmall-heart-small-diaphragm-bronchogenic0
C88-Melanocyte-melanoma-Macrophage-Mesenchymal-migratory-Dendritic-Monocytederived0
C89-small-retinoblastoma-medulloblastoma-iPS-acantholytic-eye-bronchogenic0
C9-skeletal-diaphragm-tongue-throat-penis-heart-left0
C90-neuroectodermal-peripheral-neuroepithelioma-neuroblastoma-carcinoid-parietal-putamen0
C91-Fibroblast-Smooth-mesenchymal-Mesothelial-Small-Preadipocyte-Hair0
C92-CD14CD16-CD14-Eosinophils-Basophils-Neutrophils-Macrophage-Whole0
C93-chronic-acute-leukemia-acantholytic-medulloblastoma-testis-papillotubular0
C94-smallcell-adrenal-lung-nonsmall-small-somatostatinoma-teratocarcinoma0
C95-lung-aorta-trachea-penis-Alveolar-throat-endometrioid0
C96-non-acute-tonsil-spleen-Burkitt-lymphoma-appendix0
C97-small-smallcell-gastrointestinal-argyrophil-putamen-duodenum-brain0
C98-CD8-Natural-Basophils-blood-CD4-Peripheral-Whole0
C99-hairy-mycosis-submaxillary-salivary-cord-kidney-parotid0



Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data



TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample


JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs12859

Jaspar motifP-value
MA0002.20.318
MA0003.10.205
MA0004.10.651
MA0006.10.478
MA0007.10.555
MA0009.10.465
MA0014.10.488
MA0017.10.0027
MA0018.20.0175
MA0019.10.67
MA0024.12.98201e-6
MA0025.10.893
MA0027.10.431
MA0028.10.511
MA0029.10.928
MA0030.10.58
MA0031.10.291
MA0035.20.165
MA0038.10.00588
MA0039.20.562
MA0040.10.112
MA0041.10.0299
MA0042.10.212
MA0043.10.971
MA0046.10.658
MA0047.20.0992
MA0048.10.152
MA0050.10.011
MA0051.10.169
MA0052.10.0015
MA0055.10.145
MA0057.10.48
MA0058.10.606
MA0059.10.957
MA0060.14.2783e-12
MA0061.10.0152
MA0062.20.92
MA0065.20.00402
MA0066.10.178
MA0067.10.393
MA0068.10.976
MA0069.10.726
MA0070.10.00941
MA0071.10.543
MA0072.10.752
MA0073.10.622
MA0074.10.523
MA0076.10.49
MA0077.10.12
MA0078.10.954
MA0079.20.55
MA0080.22.61347e-11
MA0081.10.0219
MA0083.10.275
MA0084.10.561
MA0087.10.38
MA0088.10.63
MA0090.10.763
MA0091.10.133
MA0092.10.13
MA0093.10.516
MA0099.21.69684e-6
MA0100.10.351
MA0101.10.0289
MA0102.20.00211
MA0103.10.0359
MA0104.20.459
MA0105.10.00324
MA0106.10.106
MA0107.10.00511
MA0108.20.189
MA0111.10.989
MA0112.20.00101
MA0113.10.677
MA0114.10.0759
MA0115.10.597
MA0116.10.012
MA0117.10.478
MA0119.10.0926
MA0122.10.347
MA0124.10.647
MA0125.10.0282
MA0131.10.393
MA0135.10.275
MA0136.18.40873e-12
MA0137.20.0483
MA0138.20.0759
MA0139.10.2
MA0140.10.125
MA0141.10.38
MA0142.10.21
MA0143.10.869
MA0144.10.0515
MA0145.10.064
MA0146.10.137
MA0147.10.52
MA0148.10.0375
MA0149.10.988
MA0150.10.0872
MA0152.10.392
MA0153.10.15
MA0154.10.0209
MA0155.10.35
MA0156.19.8592e-4
MA0157.10.0537
MA0159.10.0141
MA0160.10.205
MA0162.10.135
MA0163.14.57296e-4
MA0164.10.973
MA0258.10.0256
MA0259.10.329



FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs12859

Novel motifP-value
10.325
100.897
1000.529
1010.55
1020.521
1030.0305
1040.647
1050.219
1066.49749e-4
1070.0406
1080.957
1090.14
110.114
1100.325
1110.274
1120.072
1130.249
1140.0272
1150.81
1160.916
1170.674
1180.43
1190.0549
120.933
1200.974
1210.605
1220.523
1230.152
1240.177
1250.0938
1260.274
1270.744
1280.00775
1290.248
130.419
1300.0548
1310.243
1320.22
1330.301
1340.793
1350.119
1360.392
1370.183
1380.869
1390.00134
140.308
1400.554
1410.648
1420.843
1430.0132
1440.656
1450.067
1460.266
1470.907
1480.111
1490.097
150.318
1500.727
1510.152
1520.0354
1530.147
1540.692
1550.441
1560.594
1570.418
1580.454
1590.623
160.333
1600.439
1610.716
1620.872
1630.856
1640.684
1650.221
1660.536
1670.186
1680.163
1690.0306
170.214
180.192
190.162
20.286
200.291
210.993
220.199
230.0185
240.965
250.81
260.662
270.0442
280.963
290.668
30.0784
300.467
310.621
320.412
330.424
340.357
350.257
360.208
370.125
380.284
390.208
40.71
400.313
410.201
420.181
430.139
440.255
450.121
460.231
470.268
480.449
490.158
50.256
500.368
510.619
520.215
530.43
540.373
550.0632
560.419
570.908
580.13
590.304
60.661
600.0404
610.989
620.0758
630.142
640.491
650.0316
660.233
670.901
680.706
690.975
70.538
700.00903
710.251
720.0683
730.0748
740.213
750.539
760.462
770.137
780.564
790.0752
80.39
800.0582
810.428
820.0405
830.356
840.56
850.00242
860.417
870.907
880.274
890.0282
90.228
900.295
910.484
920.0831
930.525
940.0407
950.38
960.216
970.647
980.292
990.485



de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br> library id: CNhs12859


FANTOM5 (FF) ontology


Direct parent terms


Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data

CL: Cell type
0000000 (cell), 0000000 (cell)
0000055 (non-terminally differentiated cell)
0000003 (native cell)
0000548 (animal cell)
0002320 (connective tissue cell)
0002371 (somatic cell)
0000255 (eukaryotic cell)
0000062 (osteoblast)

UBERON: Anatomy
0000468 (multi-cellular organism)
0001474 (bone element)
0002384 (connective tissue)
0000479 (tissue)
0000062 (organ)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0004765 (skeletal element)
0002204 (musculoskeletal system)
0001434 (skeletal system)

FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0000350 (experimentally modified sample)
0000344 (0 minute sample)
0000332 (calcification induced with ascorbate and BPG sample)
0100971 (SAOS-2 cell sample)
0100385 (bone cancer cell line sample)
0100407 (osteosarcoma cell line sample)
0000593 (human Saos2 osteosarcoma cell line 0min after induction of calcification with ascorbate and BPG sample)

Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)
CL:0000335 (mesenchyme condensation cell)