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MCL coexpression mm9:1072

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Phase1 CAGE Peaks

 Short description
Mm9::chr11:45669851..45669893,+p@chr11:45669851..45669893
+
Mm9::chr14:75576396..75576412,+p9@Lcp1
Mm9::chr17:24302011..24302034,-p@chr17:24302011..24302034
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Mm9::chr7:52358439..52358450,-p@chr7:52358439..52358450
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Mm9::chr7:52358454..52358468,-p@chr7:52358454..52358468
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Mm9::chr9:108028873..108028890,-p@chr9:108028873..108028890
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Mm9::chr9:62686574..62686623,+p1@Cln6


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0042802identical protein binding0.00657390157114121
GO:0031987locomotion during locomotory behavior0.00657390157114121
GO:0001891phagocytic cup0.00657390157114121
GO:0045851pH reduction0.00657390157114121
GO:0051452cellular pH reduction0.00657390157114121
GO:0051453regulation of cellular pH0.00657390157114121
GO:0007042lysosomal lumen acidification0.00657390157114121
GO:0030641cellular hydrogen ion homeostasis0.00862777307470345
GO:0045862positive regulation of proteolysis0.0115024368688939
GO:0019864IgG binding0.0115024368688939
GO:0030004cellular monovalent inorganic cation homeostasis0.013143481366302
GO:0055067monovalent inorganic cation homeostasis0.013143481366302
GO:0001573ganglioside metabolic process0.013143481366302
GO:0005788endoplasmic reticulum lumen0.013143481366302
GO:0019865immunoglobulin binding0.0137998992205248
GO:0006687glycosphingolipid metabolic process0.0143741073271484
GO:0030162regulation of proteolysis0.0166073491042501
GO:0051017actin filament bundle formation0.0166073491042501
GO:0007040lysosome organization and biogenesis0.0174702955590397
GO:0042612MHC class I protein complex0.0174702955590397
GO:0006664glycolipid metabolic process0.0174702955590397
GO:0006885regulation of pH0.0174702955590397
GO:0006022aminoglycan metabolic process0.0174702955590397
GO:0030203glycosaminoglycan metabolic process0.0174702955590397
GO:0007033vacuole organization and biogenesis0.0174702955590397
GO:0006672ceramide metabolic process0.0195774227074295
GO:0005884actin filament0.0195774227074295
GO:0051015actin filament binding0.0196979418924547
GO:0046519sphingoid metabolic process0.0198100625757227
GO:0042611MHC protein complex0.0206794381373428
GO:0001726ruffle0.0251910804746685
GO:0007015actin filament organization0.0287009797667726
GO:0006665sphingolipid metabolic process0.0292196113910994
GO:0032403protein complex binding0.0330742153113077
GO:0019882antigen processing and presentation0.0373584336140453
GO:0006996organelle organization and biogenesis0.0396637116983314
GO:0008203cholesterol metabolic process0.0396637116983314
GO:0016125sterol metabolic process0.0417293940792968
GO:0051247positive regulation of protein metabolic process0.0417293940792968
GO:0031252leading edge0.0435394367539968
GO:0044432endoplasmic reticulum part0.0447033451764874



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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